EP1297157A2 - Regulation d'une enzyme du type protease mastocytaire humaine 6 - Google Patents

Regulation d'une enzyme du type protease mastocytaire humaine 6

Info

Publication number
EP1297157A2
EP1297157A2 EP01951617A EP01951617A EP1297157A2 EP 1297157 A2 EP1297157 A2 EP 1297157A2 EP 01951617 A EP01951617 A EP 01951617A EP 01951617 A EP01951617 A EP 01951617A EP 1297157 A2 EP1297157 A2 EP 1297157A2
Authority
EP
European Patent Office
Prior art keywords
enzyme
mast cell
polypeptide
cell protease
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP01951617A
Other languages
German (de)
English (en)
Inventor
Yonghong Xiao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of EP1297157A2 publication Critical patent/EP1297157A2/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Selon l'invention, les réactifs qui régulent l'activité d'une enzyme du type protéase mastocytaire humaine 6 et les réactifs qui se lient aux produits génétiques d'une enzyme du type protéase mastocytaire humaine 6 peuvent être utilisés pour réguler l'activité d'une enzyme du type protéase mastocytaire humaine 6. Cette régulation est particulièrement utile pour traiter la métastase de cellules malignes, l'angiogenèse tumorale, les inflammations telles que l'asthme, l'athérosclérose, les affections neurodégénératives et les infections pathogènes.
EP01951617A 2000-06-23 2001-06-21 Regulation d'une enzyme du type protease mastocytaire humaine 6 Ceased EP1297157A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21358900P 2000-06-23 2000-06-23
US213589P 2000-06-23
PCT/EP2001/007002 WO2001098340A2 (fr) 2000-06-23 2001-06-21 Regulation d'une enzyme du type protease mastocytaire humaine 6

Publications (1)

Publication Number Publication Date
EP1297157A2 true EP1297157A2 (fr) 2003-04-02

Family

ID=22795691

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01951617A Ceased EP1297157A2 (fr) 2000-06-23 2001-06-21 Regulation d'une enzyme du type protease mastocytaire humaine 6

Country Status (3)

Country Link
EP (1) EP1297157A2 (fr)
AU (1) AU2001272497A1 (fr)
WO (1) WO2001098340A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106667A2 (fr) * 2002-06-12 2003-12-24 Bayer Healthcare Ag Regulation d'une serine protease de type subtilase humaine
JP5189082B2 (ja) 2006-05-25 2013-04-24 バイエル・ファルマ・アクチェンゲゼルシャフト 二量体分子複合体
RU2471497C2 (ru) 2007-09-12 2013-01-10 Новартис Аг Мутантные антигены gas57 и антитела против gas57
WO2009081274A2 (fr) 2007-12-21 2009-07-02 Novartis Ag Formes mutantes de la streptolysine o
CA2749367A1 (fr) 2009-01-12 2010-07-15 Novartis Ag Antigenes a domaines cna_b dans des vaccins contre des bacteries a gram positif

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998033812A1 (fr) * 1997-02-05 1998-08-06 Brigham And Women's Hospital, Inc. Inhibiteurs peptidiques des proteases de mastocytes
US6274366B1 (en) * 1998-05-15 2001-08-14 Promega Corporation Enzymatically-active recombinant human β-tryptase and method of making same
WO2001070978A2 (fr) * 2000-03-20 2001-09-27 Curagen Corporation Nouveaux polypeptides et acides nucleiques codant ces polypeptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0198340A3 *

Also Published As

Publication number Publication date
WO2001098340A2 (fr) 2001-12-27
AU2001272497A1 (en) 2002-01-02
WO2001098340A3 (fr) 2002-06-06

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Legal Events

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