EP1292279A4 - Verwendung von glatiramer acetat (copolymer 1) zur behandlung von störungen des zentralen nervensystems - Google Patents
Verwendung von glatiramer acetat (copolymer 1) zur behandlung von störungen des zentralen nervensystemsInfo
- Publication number
- EP1292279A4 EP1292279A4 EP01941973A EP01941973A EP1292279A4 EP 1292279 A4 EP1292279 A4 EP 1292279A4 EP 01941973 A EP01941973 A EP 01941973A EP 01941973 A EP01941973 A EP 01941973A EP 1292279 A4 EP1292279 A4 EP 1292279A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- copolymer
- treatment
- nervous system
- central nervous
- system disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58752300A | 2000-06-05 | 2000-06-05 | |
US587523 | 2000-06-05 | ||
PCT/US2001/018248 WO2001093828A1 (en) | 2000-06-05 | 2001-06-05 | The use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1292279A1 EP1292279A1 (de) | 2003-03-19 |
EP1292279A4 true EP1292279A4 (de) | 2005-01-12 |
Family
ID=24350145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01941973A Withdrawn EP1292279A4 (de) | 2000-06-05 | 2001-06-05 | Verwendung von glatiramer acetat (copolymer 1) zur behandlung von störungen des zentralen nervensystems |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1292279A4 (de) |
JP (1) | JP2003535118A (de) |
AU (2) | AU7528001A (de) |
CA (1) | CA2411536A1 (de) |
HU (1) | HUP0302333A3 (de) |
IL (1) | IL153236A0 (de) |
PL (1) | PL363431A1 (de) |
WO (1) | WO2001093828A1 (de) |
ZA (1) | ZA200210084B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000005250A1 (en) | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
ES2527760T3 (es) | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
US6800287B2 (en) | 1998-09-25 | 2004-10-05 | Yeda Research And Development Co., Ltd. | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
ZA200206457B (en) | 2000-02-18 | 2003-08-13 | Yeda Res & Dev | Oral, nasal and pulmonary dosage formulations of copolymer 1. |
US20020077278A1 (en) | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
US7429374B2 (en) | 2001-12-04 | 2008-09-30 | Teva Pharmaceutical Industries, Ltd. | Process for the measurement of the potency of glatiramer acetate |
SI1797109T1 (sl) | 2004-09-09 | 2016-07-29 | Yeda Research And Development Co., Ltd. | Zmesi polipeptidov, sestavki, ki jih vsebujejo, in postopki za njihovo pripravo ter njihove uporabe |
KR20170123354A (ko) | 2009-08-20 | 2017-11-07 | 에다 리서치 앤드 디벨럽먼트 컴퍼니 리미티드 | 글라티라머 아세테이트를 포함하는 약제 |
USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
US8759302B2 (en) | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
JP2013541010A (ja) | 2010-10-11 | 2013-11-07 | テバ ファーマシューティカル インダストリーズ リミティド | グラチラマーアセテートに対する臨床的な反応の予測可能なバイオマーカーとしてのサイトカインバイオマーカー |
TW201326399A (zh) | 2011-10-10 | 2013-07-01 | Teva Pharma | 用於預測對格拉替雷(glatiramer)醋酸鹽之臨床反應之單核苷酸多型性之判定 |
TW201420111A (zh) | 2012-10-10 | 2014-06-01 | Teva Pharma | 對格拉默醋酸鹽(glatiramer acetate)之臨床反應具預測性之生物標記 |
UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
WO2016029920A1 (en) | 2014-08-29 | 2016-03-03 | Aarhus Universitet | Positively charged co-polymers for use as antimicrobial agents |
US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
CN106924175B (zh) * | 2015-12-29 | 2020-07-03 | 深圳翰宇药业股份有限公司 | 一种治疗多发性硬化症的药物组合物 |
US11058720B2 (en) | 2016-05-20 | 2021-07-13 | Cedars-Sinai Medical Center | Methods of treating or preventing alzheimer's disease and associated conditions |
CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995031990A1 (en) * | 1994-05-24 | 1995-11-30 | Yeda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
WO2001052878A2 (en) * | 2000-01-20 | 2001-07-26 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
WO2001093893A2 (en) * | 2000-06-07 | 2001-12-13 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9411292D0 (en) * | 1994-06-06 | 1994-07-27 | Teva Pharma | Pharmaceuticals compositions |
US5665764A (en) * | 1995-06-02 | 1997-09-09 | Warner-Lambert Company | Tricyclic inhibitors of matrix metalloproteinases |
IL119989A0 (en) * | 1997-01-10 | 1997-04-15 | Yeda Res & Dev | Pharmaceutical compositions for oral treatment of multiple sclerosis |
-
2001
- 2001-06-05 EP EP01941973A patent/EP1292279A4/de not_active Withdrawn
- 2001-06-05 PL PL01363431A patent/PL363431A1/xx not_active Application Discontinuation
- 2001-06-05 HU HU0302333A patent/HUP0302333A3/hu unknown
- 2001-06-05 AU AU7528001A patent/AU7528001A/xx active Pending
- 2001-06-05 AU AU2001275280A patent/AU2001275280B2/en not_active Ceased
- 2001-06-05 JP JP2002501401A patent/JP2003535118A/ja active Pending
- 2001-06-05 IL IL15323601A patent/IL153236A0/xx unknown
- 2001-06-05 CA CA002411536A patent/CA2411536A1/en not_active Abandoned
- 2001-06-05 WO PCT/US2001/018248 patent/WO2001093828A1/en not_active Application Discontinuation
-
2002
- 2002-12-12 ZA ZA200210084A patent/ZA200210084B/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995031990A1 (en) * | 1994-05-24 | 1995-11-30 | Yeda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
WO2001052878A2 (en) * | 2000-01-20 | 2001-07-26 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
WO2001093893A2 (en) * | 2000-06-07 | 2001-12-13 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
Non-Patent Citations (4)
Title |
---|
AHARONI R ET AL: "COP 1 SPECIFIC SUPPRESSOR CELLS INHIBIT EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS INDUCED BY EITHER MOUSE SPINAL CORD HOMOGENATE ORPROTEOLIPID PROTEIN PEPTIDE 139-151", NEUROLOGY, LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, US, vol. 48, no. 3, SUPPL 2, 12 April 1997 (1997-04-12), pages A422, XP001029141, ISSN: 0028-3878 * |
AHARONI R ET AL: "COPOLYMER 1 INDUCES T CELLS OF THE T HELPER TYPE 2 THAT CROSSREACT WITH MYELIN BASIC PROTEIN AND SUPPRESS EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 94, September 1997 (1997-09-01), pages 10821 - 10826, XP002918836, ISSN: 0027-8424 * |
See also references of WO0193828A1 * |
TEVA ET AL: "COPOLYMER-1 GLATIRAMER ACETATE COPAXONE(R) AGENT FOR MULTIPLE SCLEROSIS", DRUGS OF THE FUTURE, BARCELONA, ES, vol. 23, no. 2, 1998, pages 213 - 214, XP001029138, ISSN: 0377-8282 * |
Also Published As
Publication number | Publication date |
---|---|
HUP0302333A3 (en) | 2005-07-28 |
ZA200210084B (en) | 2003-12-12 |
HUP0302333A2 (hu) | 2003-11-28 |
CA2411536A1 (en) | 2001-12-13 |
JP2003535118A (ja) | 2003-11-25 |
WO2001093828A1 (en) | 2001-12-13 |
PL363431A1 (en) | 2004-11-15 |
IL153236A0 (en) | 2003-07-06 |
AU7528001A (en) | 2001-12-17 |
EP1292279A1 (de) | 2003-03-19 |
AU2001275280B2 (en) | 2006-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030102 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20041126 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20070127 |