EP1268067A1 - Pipette provided with sampled volume adjusting means - Google Patents

Pipette provided with sampled volume adjusting means

Info

Publication number
EP1268067A1
EP1268067A1 EP01921520A EP01921520A EP1268067A1 EP 1268067 A1 EP1268067 A1 EP 1268067A1 EP 01921520 A EP01921520 A EP 01921520A EP 01921520 A EP01921520 A EP 01921520A EP 1268067 A1 EP1268067 A1 EP 1268067A1
Authority
EP
European Patent Office
Prior art keywords
pipette
adjustment
pipette according
locking element
axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP01921520A
Other languages
German (de)
French (fr)
Other versions
EP1268067B1 (en
Inventor
François VIOT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilson SAS
Original Assignee
Gilson Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilson Inc filed Critical Gilson Inc
Priority to DK01921520T priority Critical patent/DK1268067T3/en
Publication of EP1268067A1 publication Critical patent/EP1268067A1/en
Application granted granted Critical
Publication of EP1268067B1 publication Critical patent/EP1268067B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED

Definitions

  • sampling pipette provided with means for adjusting the volume to be sampled
  • the invention relates to liquid sampling pipettes.
  • a sampling pipette comprising a wheel accessible through a window of the body of the pipette to adjust the volume of liquid to be pipetted. This volume is also indicated on a display.
  • This pipette has many advantages. The knob does not protrude from the body of the pipette and is therefore unlikely to be actuated unintentionally.
  • the wheel is braked in its operation by a friction assembly which further reduces the risk of disruption.
  • a friction assembly which further reduces the risk of disruption.
  • it is desirable to improve it further. Indeed, there remains a low risk of accidental disruption of the volume to be pipetted by an involuntary operation of the wheel.
  • An object of the invention is to provide a pipette of a different type but also avoiding untimely adjustment.
  • a sampling pipette comprising means for adjusting a volume of liquid to be sampled comprising at least one adjustment control member, the pipette comprising a movable blocking element between an inactive position in which it renders the adjustment means unsuitable for adjustment and an active position in which it renders the adjustment means suitable for adjustment, the locking element being the adjustment control member.
  • pipette according to the invention allows the use to perform by means of the single locking element all the successive operations relating to the adjustment, for example unlocking, volume adjustment and locking.
  • the invention may also have at least any one of the following characteristics: - the blocking element is movable by sliding between the two positions; - The locking element is arranged to be directly actuated from one to the other of the two positions by a user;
  • the blocking element extends inside a pipette body
  • the pipette is arranged so that the blocking element is capable of transmitting an adjustment movement to a member of the adjustment means in the active position, and is incapable of this transmission in the inactive position;
  • the pipette is arranged so that the blocking element is capable of transmitting a movement from one to the other of two members of the adjustment means other than the blocking element in the active position and is incapable of this transmission. in the inactive position;
  • the adjustment means comprise two members arranged to be in mutual engagement when the blocking element is in the active position and to be disengaged from each other when the blocking element is in the inactive position;
  • the pipette has two adjustment control members
  • the pipette includes a sampling control button forming an adjustment control member
  • the pipette includes means for returning the blocking element to the inactive position
  • the pipette includes means for holding the blocking element in the active position against the return means; the pipette is arranged so that the blocking element is capable of passing from the active position of the inactive position with crossing a hard point, and vice versa, and
  • the adjustment means comprise a drive member and a receiver member capable of being driven by the drive member by means of a link by complementary shape, one of the drive and receiver members being deformable so as to interrupt the link when 'it is subjected to a stress of intensity greater than a predetermined intensity.
  • FIG. 2 is a perspective view of part of the pipette adjustment mechanism of Figure 1;
  • - Figure 3 is an enlarged view of the mechanism of Figure 2;
  • FIG. 4 is an axial sectional view of the mechanism of Figure 2;
  • FIG. 5 is a perspective view of a sub-part of the mechanism of Figure 2;
  • FIG. 6 is an elevational view of the sub-part of Figure 5;
  • FIG. 7 is a perspective view of the dog clutch and the trainer of the mechanism of Figure 4;
  • - Figures 8 to 11 are four partial views in axial section showing different stages of the cooperation of the adjustment knob and the coupler of the mechanism of FIG. 4;
  • FIG. 12 is a cross-sectional view of the sub-part of Figure 6 along the plane XII-XII;
  • - Figure 13 is an exploded sectional view of certain elements of Figure 12;
  • FIG. 14 is a sectional view of the adjusting screw alone
  • Figure 19 is a view similar to Figure 12 showing an alternative embodiment of the invention.
  • sampling pipette is of the same type as that of document FR-2 696 110. Reference will therefore be made to this document for certain details of the pipette already known from this document. Only certain aspects of the volume control mechanism will be described here in detail.
  • the pipette 2 conventionally comprises a body 2 serving as a handle to be grasped by the hand of the user.
  • the pipette comprises a piston (not shown) movable to slide along a longitudinal axis 10 of the pipette in a lower cavity of the pipette in order to draw therein a volume of liquid to be withdrawn or to expel it from this cavity.
  • the displacement of the piston is controlled in particular by means of a control rod 4 of axis 10 connected in the lower part to the piston by parts of a known type and not illustrated.
  • This rod 4 is surmounted at its upper end by a push button 6 rigidly fixed to the rod, which the user can operate with the thumb of the hand holding the pipette.
  • the pipette includes a return spring capable of replacing the piston and the rod in the upper part at the end of their downward stroke for expelling the liquid, and a purge spring adding its effect to that of the preceding spring when the stroke piston continues down for a purge stroke.
  • the volume to be pipetted during a normal full stroke of the piston, excluding the purge stroke, can be controlled by means of an adjustment button 8 in the form of a ring and of push button 6. These two buttons are mounted for rotation around the longitudinal axis 10 of the pipette. A rotation of one or other of these buttons causes the rotation of an adjustment screw 5 coaxial with the rod 4 around its axis 10. The way in which the rotation of the screw 5 causes the variation of the volume to be pipetted is known and will not be described. We will now describe in detail the upper part of the adjustment mechanism.
  • the pipette comprises a coupler 12 mounted to slide on the rod 4 but fixed in rotation relative to the latter.
  • the coupler has a central upper orifice having three radial engaging tabs 14 in three longitudinal grooves 16 of the rod 4. This orifice is formed by an upper washer 18 of the coupler.
  • the coupler has three arms 20 extending downward parallel to the axis 10 from the washer 18. Each arm 20 is generally flattened in the direction radial to the axis 10 and has on its face 22 opposite the axis a relief 24 elongated in the circumferential direction to the axis 10.
  • the adjustment knob 8 is movable sliding along axis 10 and rotating about this axis.
  • the button 8 has an essentially cylindrical shape with an axis 10.
  • the external face 26 of this button is accessible to the user for its operation through windows of the body. To this end, it includes gripping reliefs.
  • the button 8 Near its upper circular edge, the button 8 has three forks 30 extending e r projecting radially towards the axis. These forks have a female “U” shape open in the direction of the axis, of shape complementary to the profile of the arms 20 and receiving the latter respectively.
  • the button 8 is fixed in rotation to the coupler 12 but is not fixed there in sliding.
  • the button 8 can occupy on the one hand a low position, or inactive position, or locked position, and on the other hand a high or active or unlocked position. These two positions are independent of the angular position of the button 8 around the axis.
  • the button switches from one to the other position by sliding along the axis.
  • the coupler 12 comprises an annular spring 26 of axis 1C urging the arms 20 radially on their internal face so as to tend to distance them radially from the axis.
  • the arms 20 are received in the forks but not the reliefs 24. It is the same in the high position, as illustrated in FIG. 11.
  • the reliefs 24 pass through the forks and cause the temporary bending of the arms 20 in the radial direction. This passage produces an audible click and constitutes a hard point during the maneuver which manifests for the user the change of high or low position.
  • the reliefs 24 hold the button in the high position against the return spring, unless the user acts otherwise.
  • the pipette comprises a dog clutch 32 of general cylindird ⁇ que shape having an external annular peripheral rib 34 at about half height.
  • the button 8 comprises two cylindrical pieces 8a and 8b, lower and upper, force-fitted externally on the dog clutch 32 and in axial support on the rib 34.
  • the button 8 is rigidly fixed to the dog clutch.
  • the sliding sleeve has on its outer surface, illustrated in detail in FIG 1 r reliefs co-operating with complementary reliefs button to make these rigid bonds.
  • the craoot 32 has a toothing 36 extending near the upper boron, projecting radially from its internal face in the direction of the axis.
  • the pipette comprises a driver 38 having an upper part 40 of cylindrical shape provided with several teeth 42, for example two in number, extending near its upper edge, projecting radially from its external face in a direction opposite to the axis . These two teeth are capable of engaging with the teeth 36 of the dog clutch when they extend at the same height as the latter along the axis 10.
  • the driver 38 can be made movable relative to the adjustment screw 5. It extends directly opposite the latter radially. Unlike the adjusting screw 5 which is movable in a helical movement around the axis 10, the driver 38 is fixed to slide along the axis 10 relative to the body of the pipette.
  • the coach 38 has two main legs 48 and two legs secondary 50 extending parallel: to the axis 10 downwards from the upper part 40.
  • the secondary legs 50 have a cylinder sector shape with an axis 10. They alternate around the axis with the legs main 48.
  • the main tabs 48 have a cylindrical external face and have a flat internal surface projecting radially from which extends a rib 52 profiled parallel to the axis 10 and of rectangular section.
  • the driver 38 includes a spring 54 externally encircling the four tabs 48, 50 and housed in an external notch thereof.
  • the spring tends to bring the tabs radially from the axis.
  • the adjusting screw 5 is hollow and traversed longitudinally by the control rod 4. These two parts are completely independent in their relative movement.
  • the adjusting screw 5 has a generally circular shape of revolution. However, more specifically, it has two flats 56 parallel to each other and to the axis 10 and opposite on either side of this axis. These flats extend over a middle portion 58 of the screw extending above a threaded lower portion 60 of the screw used for adjusting the volume. These flats 56 are joined to each other by arcs of a circle 61.
  • the adjusting screw also has two longitudinal pins 6 o parallel to the axis 10, extending to the edge of the respective flats so as to present a stop when circumferentially traversing the external face of the screw 5 from the flats, but also so as to present an arc of a circle not forming a stop from the cylindrical zones 61.
  • the two pins 62 are not symmetrical to each other with respect to the axis 10 but are so with respect to a median plane of the screw parallel to the two flats. In addition, the two pins 62 do not extend exactly in coincidence with regard to their position along the axis 10. They overlap over a certain section. But one of the lugs extends higher than the other while the latter extends downwards more than the first. Also, the two lugs are in partial overlap along the axis 10. The longitudinal position of the second lug, normally hidden in FIG. 6, has however been indicated by the line 56.
  • the driver 38 can be coupled to the screw 5 in rotation, or uncoupled from the latter.
  • the driver When it is coupled, as in FIGS. 12 and 15, the driver is located at a level with the screw on which the two lugs 62 overlap.
  • the secondary tabs 48 are in abutment on the cylindrical zones 61 of which they match the form. They make surface-to-surface contact with them.
  • the ribs 52 are in radial abutment on the flats 56 and in abutment on the respective lugs 62.
  • the spring 54 keeps the four tabs resting on the screw 5 and in particular maintains the grip of the ribs on the pins. Consequently, a rotary movement of the driver 38 can be transmitted to the adjustment screw 5.
  • the low, inactive, locked position of the button is illustrated in FIGS. 1, 3 and 4.
  • the arms 20 are engaged with the button 8.
  • the rod 4 is therefore secured in rotation of the button 8.
  • the teeth 36 of the dog clutch are out of engagement with the teeth 42 of the driver 38.
  • No movement of the knob 8 therefore causes the driver 38 or the screw 5 to rotate.
  • This position button 8 low therefore deactivates the adjustment means.
  • the volume to be pipetted cannot therefore be changed voluntarily or involuntarily.
  • the words “locked” or “locked” written on the external face 26 of the button 8 appear in the window intended for the user.
  • a direct stress on the button 8 or on the rotary button 6 exerted by the user is therefore transmitted by the teeth 36, 42 to the 'coach 38, then to the adjusting screw 5 insofar as the latter is not already at the end of its travel for the desired direction of adjustment.
  • the user again slides the button 8 in the low position to prevent inadvertent adjustment.
  • FIG. 19 illustrates an alternative embodiment in which the analogous elements have numerical references increased by 100.
  • the rod 104 has not been illustrated.
  • the ribs 152 have a “V” profile with rounded tip.
  • the flats 156 are replaced by grooves 156 with a “V” profile of the same angle as that of the ribs to allow the driving of the screw 105 by the driver 138.
  • the respective grooves widen. by accentuating the inclination of one of their two faces. This face forms a ramp.
  • the pipette is arranged so that, when the end position is reached, the spring clamping force is insufficient to hold the ribs 152 in the grooves 156.
  • the ramp then causes the ribs to exit from the grooves and the spacing of the main legs 148, so that the driver no longer drives the screw and continues to rotate alone.
  • the pipette may include electronic display means (for example with liquid crystal) of a parameter relating to the operation of the pipette.
  • these means may permanently indicate the locked or unlocked state of the button 8.

Abstract

The sampling pipette includes means for adjusting the volume of liquid to be taken. It includes a locking element that is movable between an inactive position in which it makes the adjustment means unsuitable for performing adjustment and an active position in which it makes the adjustment means suitable for performing adjustment.

Description

«Pipette de prélèvemen t munie de moyens de réglage du vol ume à prél ever» L'invention concerne les pipettes de prélèvement de liquide. "Sampling pipette provided with means for adjusting the volume to be sampled" The invention relates to liquid sampling pipettes.
On connaît, par exemple du document FR-2 696 110, une pipette de prélèvement comprenant une mollette accessible à travers une fenêtre du corps de la pipette pour régler le volume de liquide a pipeter. Ce volume est par ailleurs indiqué sur un afficheur. Cette pipette présente de nombreux avantages. La mollette ne fait pas saillie hors du corps de la pipette et est donc peu susceptible d'être actionnée involontairement.We know, for example from document FR-2 696 110, a sampling pipette comprising a wheel accessible through a window of the body of the pipette to adjust the volume of liquid to be pipetted. This volume is also indicated on a display. This pipette has many advantages. The knob does not protrude from the body of the pipette and is therefore unlikely to be actuated unintentionally.
De plus, la mollette est freinée dans sa manœuvre par un assemblage à friction qui réduit encore les risques de dérèglement. Toutefois, il est souhaitable de la perfectionner encore. En effet, il demeure un faible risque de dérèglement accidentel du volume à pipeter par une manœuvre involontaire de la molette.In addition, the wheel is braked in its operation by a friction assembly which further reduces the risk of disruption. However, it is desirable to improve it further. Indeed, there remains a low risk of accidental disruption of the volume to be pipetted by an involuntary operation of the wheel.
On souhaite donc éliminer tout risque de dérèglement accidentel du volume a pipeter. Le document US-5 849 248 divulgue une pipette comprenant un élément de blocage mobile entre une position inactive dans laquelle il rend les moyens de réglage inaptes au réglage et une position active dans laquelle il les y rend aptes. Cet élément s'étend a proximité du bouton de réglage du volume. Aucun déréglage intempestif du volume a pipetter n'est donc plus à craindre.We therefore wish to eliminate any risk of accidental disruption of the volume to be pipetted. Document US Pat. No. 5,849,248 discloses a pipette comprising a movable blocking element between an inactive position in which it makes the adjustment means unsuitable for adjustment and an active position in which it makes them suitable for it. This element extends near the volume control knob. No untimely adjustment of the volume to be pipetted is therefore no longer to be feared.
Un but de l'invention est de fournir une pipette d'un type différent mais évitant elle aussi le deréglage intempestif. En vue de la réalisation de ce but, on prévoit selon l'invention une pipette de prélèvement comportant des moyens de réglage d'un volume de liquide à prélever comprenant au moins un organe de commande de réglage, la pipette comprenant un élément de blocage mobile entre une position inactive dans laquelle il rend les moyens de réglage inaptes au réglage et une position active dans laquelle il rend les moyens de réglage aptes au réglage, l'élément de blocage étant l'organe de commande de réglage.An object of the invention is to provide a pipette of a different type but also avoiding untimely adjustment. In order to achieve this goal, there is provided according to the invention a sampling pipette comprising means for adjusting a volume of liquid to be sampled comprising at least one adjustment control member, the pipette comprising a movable blocking element between an inactive position in which it renders the adjustment means unsuitable for adjustment and an active position in which it renders the adjustment means suitable for adjustment, the locking element being the adjustment control member.
Ainsi, lorsque l'élément de blocage est en position inactive, aucun dérèglement accidentel du volume à pipeter n'est possible. De plus, cette élimination des risques de dérèglement permet en retour de supprimer ou de réduire le freinage à friction de la mollette, ce qui rend sa manœuvre plus facile lors d'un réglage volontaire. Cette suppression est d'autant plus agréable qu' il pouvait arriver avec la pipette antérieure du document FR-2 696 110 que le gant du manipulateur se coince entre la mollette et le corps de la pipette lors de l' actionnement de la mollette. Cet inconvénient peut donc être lui aussi éliminé.Thus, when the blocking element is in the inactive position, no accidental adjustment of the volume to be pipetted is possible. In addition, this elimination of the risk of disruption allows in return to remove or reduce the friction braking of the wheel, which makes it easier to maneuver during voluntary adjustment. This deletion is all the more pleasant since it could happen with the front pipette of document FR-2 696 110 that the glove of the manipulator gets stuck between the wheel and the body of the pipette during the actuation of the wheel. This drawback can therefore also be eliminated.
De plus, la pipette selon l'invention permet à l'utilisation d'effectuer au moyen du seul élément de blocage toutes les opérations successives relatives au réglage, par exemple déverrouillage, réglage du volume et verrouillage.In addition, the pipette according to the invention allows the use to perform by means of the single locking element all the successive operations relating to the adjustment, for example unlocking, volume adjustment and locking.
L' invention pourra en outre présenter au moins l'une quelconque des caractéristiques suivantes : - l'élément de blocage est mobile à coulissement entre les deux positions ; - l'élément de blocage est agencé pour être directement actionné de l'une à l'autre des deux positions par un utilisateur ;The invention may also have at least any one of the following characteristics: - the blocking element is movable by sliding between the two positions; - The locking element is arranged to be directly actuated from one to the other of the two positions by a user;
- l'élément de blocage s'étend a l'intérieur d'un corps de la pipette- the blocking element extends inside a pipette body
- la pipette est agencée de sorte que l'élément de blocage est apte à transmettre un mouvement de réglage à un organe des moyens de réglage en position active, et est inapte à cette transmission en position inactive ;- The pipette is arranged so that the blocking element is capable of transmitting an adjustment movement to a member of the adjustment means in the active position, and is incapable of this transmission in the inactive position;
- la pipette est agencée de sorte que l'élément de blocage est apte à transmettre un mouvement de l'un a l'autre de deux organes des moyens de réglage autres que l'élément de blocage en position active et est inapte à cette transmission en position inactive ;- The pipette is arranged so that the blocking element is capable of transmitting a movement from one to the other of two members of the adjustment means other than the blocking element in the active position and is incapable of this transmission. in the inactive position;
- le mouvement est une rotation ; les moyens de réglage comprennent deux organes agencés pour être en crabotage mutuel lorsque l'élément de blocage est en position active et pour être désengagés l'un de l'autre lorsque l'élément de blocage est en position inactive ;- the movement is a rotation; the adjustment means comprise two members arranged to be in mutual engagement when the blocking element is in the active position and to be disengaged from each other when the blocking element is in the inactive position;
- la pipette comporte deux organes de commande de réglage ;- The pipette has two adjustment control members;
- la pipette comporte un bouton de commande de prélèvement formant un organe de commande de réglage ;- The pipette includes a sampling control button forming an adjustment control member;
- la pipette comporte des moyens de rappel de l'élément de blocage dans la position inactive ;- The pipette includes means for returning the blocking element to the inactive position;
- la pipette comporte des moyens pour maintenir l'élément de blocage dans la position active a 1' encontre des moyens de rappel ; la pipette est agencée de sorte que l'élément de blocage est apte à passer de la position active d la position inactive avec franchissement d'un point dur, et inversement, et- The pipette includes means for holding the blocking element in the active position against the return means; the pipette is arranged so that the blocking element is capable of passing from the active position of the inactive position with crossing a hard point, and vice versa, and
- les moyens de réglage comportent un organe moteur et un organe récepteur apte à être entraîné par l'organe moteur au moyen d'une liaison par complémentarité de forme, l'un des organes moteur et récepteur étant deformable de façon à interrompre la liaison lorsqu'il est soumis à une sollicitation d'intensité supérieure a une intensité prédéterminée. D'autres caractéristiques et avantages de l'invention apparaîtront encore dans la description suivante d'un mode préféré de réalisation et d'une variante donnés à titre d'exemples non limitatifs. Aux dessins annexés : - la figure 1 est une vue partielle en coupe axiale d'une pipette selon un mode préféré de réalisation de 1' invention ;the adjustment means comprise a drive member and a receiver member capable of being driven by the drive member by means of a link by complementary shape, one of the drive and receiver members being deformable so as to interrupt the link when 'it is subjected to a stress of intensity greater than a predetermined intensity. Other characteristics and advantages of the invention will become apparent in the following description of a preferred embodiment and of a variant given by way of nonlimiting examples. In the accompanying drawings: - Figure 1 is a partial view in axial section of a pipette according to a preferred embodiment of one invention;
- la figure 2 est une vue en perspective d'une partie du mécanisme de réglage de la pipette de la figure 1 ; - la figure 3 est une vue à plus grande échelle du mécanisme de la figure 2 ;- Figure 2 is a perspective view of part of the pipette adjustment mechanism of Figure 1; - Figure 3 is an enlarged view of the mechanism of Figure 2;
- la figure 4 est une vue en section axiale du mécanisme de la figure 2 ;- Figure 4 is an axial sectional view of the mechanism of Figure 2;
- la figure 5 est une vue en perspective d'une sous- partie du mécanisme de la figure 2 ;- Figure 5 is a perspective view of a sub-part of the mechanism of Figure 2;
- la figure 6 est une vue en élévation de la sous- partie de la figure 5 ;- Figure 6 is an elevational view of the sub-part of Figure 5;
- la figure 7 est une vue en perspective du crabot et de l'entraîneur du mécanisme de la figure 4 ; - les figures 8 à 11 sont quatre vues partielles en coupe axiale montrant différentes étapes de la coopération du bouton de réglage et du coupleur du mécanisme de la figure 4 ;- Figure 7 is a perspective view of the dog clutch and the trainer of the mechanism of Figure 4; - Figures 8 to 11 are four partial views in axial section showing different stages of the cooperation of the adjustment knob and the coupler of the mechanism of FIG. 4;
- la figure 12 est une vue en coupe transversale de la sous-partie de la figure 6 suivant le plan XII-XII ; - la figure 13 est une vue en coupe éclatée de certains éléments de la figure 12 ;- Figure 12 is a cross-sectional view of the sub-part of Figure 6 along the plane XII-XII; - Figure 13 is an exploded sectional view of certain elements of Figure 12;
- la figure 14 est une vue en coupe de la vis de réglage seule ;- Figure 14 is a sectional view of the adjusting screw alone;
- les figures 15 à 18 illustrent différentes étapes de la coopération des éléments de la figure 12 ; et- Figures 15 to 18 illustrate different stages of the cooperation of the elements of Figure 12; and
- la figure 19 est une vue analogue à la figure 12 montrant une variante de réalisation de l'invention.- Figure 19 is a view similar to Figure 12 showing an alternative embodiment of the invention.
La pipette de prélèvement selon le présent mode de réalisation de l'invention est du même type que celle du document FR-2 696 110. On se référera donc à ce document pour certains détails de la pipette déjà connus de ce document. On ne décrira ici en détail que certains aspects du mécanisme de réglage du volume.The sampling pipette according to the present embodiment of the invention is of the same type as that of document FR-2 696 110. Reference will therefore be made to this document for certain details of the pipette already known from this document. Only certain aspects of the volume control mechanism will be described here in detail.
La pipette 2 comprend classiquement un corps 2 servant de poignée à saisir par la main de l'utilisateur. La pipette comporte un piston non illustré mobile à coulissement suivant un axe longitudinal 10 de la pipette dans une cavité inférieure de la pipette afin d'aspirer dans celle-ci un volume de liquide à prélever ou de l'expulser hors de cette cavité. Le déplacement du piston est commande notamment au moyen d'une tige de commande 4 d'axe 10 reliée en partie inférieure au piston par des pièces d'un type connu et non illustrées. Cette tige 4 est surmontée à son extrémité supérieure par un bouton poussoir 6 rigidement fixé à la tige, que l'utilisateur peut actionner avec le pouce de la main tenant la pipette. Ainsi le piston s'abaisse et remonte en fonction du même mouvement du bouton. La pipette comporte un ressort de rappel apte a replacer le piston et la tige en partie haute à la fin de leur course vers le bas pour l'expulsion du liquide, et un ressort de purge ajoutant son effet a celui du précèdent ressort lorsque la course du piston se poursuit vers le bas pour une course de purge.The pipette 2 conventionally comprises a body 2 serving as a handle to be grasped by the hand of the user. The pipette comprises a piston (not shown) movable to slide along a longitudinal axis 10 of the pipette in a lower cavity of the pipette in order to draw therein a volume of liquid to be withdrawn or to expel it from this cavity. The displacement of the piston is controlled in particular by means of a control rod 4 of axis 10 connected in the lower part to the piston by parts of a known type and not illustrated. This rod 4 is surmounted at its upper end by a push button 6 rigidly fixed to the rod, which the user can operate with the thumb of the hand holding the pipette. Thus the piston lowers and goes up according to the same movement of the button. The pipette includes a return spring capable of replacing the piston and the rod in the upper part at the end of their downward stroke for expelling the liquid, and a purge spring adding its effect to that of the preceding spring when the stroke piston continues down for a purge stroke.
Le volume a pipeter durant une course normale complète du piston, hors course de purge, peut être régie au moyen d'un bouton de réglage 8 en forme de bague et du bouton-poussoir 6. Ces deux boutons sont montes a rotation autour de l'axe longitudinal 10 de la pipette. Une rotation de l'un ou l'autre de ces boutons provoque la rotation d'une vis de réglage 5 coaxiale a la tige 4 autour de son axe 10. La façon dont la rotation de la vis 5 entraîne la variation du volume a pipeter est connue et ne sera pas décrite. On va maintenant décrire en détail la partie supérieure du mécanisme de réglage.The volume to be pipetted during a normal full stroke of the piston, excluding the purge stroke, can be controlled by means of an adjustment button 8 in the form of a ring and of push button 6. These two buttons are mounted for rotation around the longitudinal axis 10 of the pipette. A rotation of one or other of these buttons causes the rotation of an adjustment screw 5 coaxial with the rod 4 around its axis 10. The way in which the rotation of the screw 5 causes the variation of the volume to be pipetted is known and will not be described. We will now describe in detail the upper part of the adjustment mechanism.
Toutes les pièces qui vont maintenant être décrites ont l'axe 10 pour axe de symétrie, saut indication contraire.All the parts which will now be described have axis 10 as the axis of symmetry, jump otherwise indicated.
En référence aux figures 1 a 4, la pipette comporte un coupleur 12 monte a coulissement sur la tige 4 mais fixe en rotation par rapport a celle-ci A cette fin, le coupleur présente un orifice supérieur central présentant trois pattes 14 radiales s' engageant dans trois gorges longitudinales 16 de la tige 4. Cet orifice est forme par une rondelle supérieure 18 du coupleur. Le coupleur comporte trois bras 20 s' étendant vers le bas parallèlement a l'axe 10 a partir de la rondelle 18. Chaque bras 20 est globalement aplati suivant la direction radiale à l'axe 10 et présente sur sa face 22 opposée à l'axe un relief 24 allongé suivant la direction circonférentielle à l'axe 10. Le bouton de réglage 8 est mobile à coulissement suivant l'axe 10 et à rotation autour de cet axe. Il présente une forme essentiellement cylindrique d' axe 10. La face externe 26 de ce bouton est accessible a l'utilisateur pour sa manœuvre à travers des fenêtres du corps. Elle comporte à cette fin des reliefs de préhension. Près de son bord circulaire supérieur, le bouton 8 comporte trois fourches 30 s' étendant er saillie radiale en direction de l'axe. Ces fourches présentent une forme femelle en « U » ouverte en direction de l'axe, de forme complémentaire au profil des bras 20 et recevant ceux-ci respectivement.With reference to FIGS. 1 to 4, the pipette comprises a coupler 12 mounted to slide on the rod 4 but fixed in rotation relative to the latter. To this end, the coupler has a central upper orifice having three radial engaging tabs 14 in three longitudinal grooves 16 of the rod 4. This orifice is formed by an upper washer 18 of the coupler. The coupler has three arms 20 extending downward parallel to the axis 10 from the washer 18. Each arm 20 is generally flattened in the direction radial to the axis 10 and has on its face 22 opposite the axis a relief 24 elongated in the circumferential direction to the axis 10. The adjustment knob 8 is movable sliding along axis 10 and rotating about this axis. It has an essentially cylindrical shape with an axis 10. The external face 26 of this button is accessible to the user for its operation through windows of the body. To this end, it includes gripping reliefs. Near its upper circular edge, the button 8 has three forks 30 extending e r projecting radially towards the axis. These forks have a female “U” shape open in the direction of the axis, of shape complementary to the profile of the arms 20 and receiving the latter respectively.
Il découle de cet agencement que le bouton 8 est fixé en rotation au coupleur 12 mais n' y est pas fixe en coulissement. Le bouton 8 peut occuper d'une part une position basse, ou position inactive, ou position verrouillée, et d'autre part une position haute ou active ou déverrouillée. Ces deux positions sent indépendantes de la position angulaire du bouton 8 autour de l'axe. Le bouton passe de l'une à l'autre position par coulissement suivant l'axe. Le coupleur 12 comporte un ressort annulaire 26 d'axe 1C sollicitant radialement les bras 20 sur leur face interne pour tendre à les éloigner radialement de l'axe.It follows from this arrangement that the button 8 is fixed in rotation to the coupler 12 but is not fixed there in sliding. The button 8 can occupy on the one hand a low position, or inactive position, or locked position, and on the other hand a high or active or unlocked position. These two positions are independent of the angular position of the button 8 around the axis. The button switches from one to the other position by sliding along the axis. The coupler 12 comprises an annular spring 26 of axis 1C urging the arms 20 radially on their internal face so as to tend to distance them radially from the axis.
En position basse, comme illustré aux figures 1-4 et 8, les bras 20 sont reçus dans les fourches mais pas les reliefs 24. Il en est de même en position haute, comme illustré à la figure 11. Au cours du mouvement de passage de l'une à l'autre position, illustre aux figures 8 à 11, les reliefs 24 passent dans les fourches et provoquent la flexion temporaire des bras 20 en direction radiale. Ce passage produit un clic sonore et constitue un point dur lors de la manœuvre qui manifestent pour l'utilisateur le changement de position haute ou basse. De plus, les reliefs 24 maintiennent le bouton en position haute a l' encontre du ressort de rappel, sauf action contraire de l'utilisateur.In the low position, as illustrated in FIGS. 1-4 and 8, the arms 20 are received in the forks but not the reliefs 24. It is the same in the high position, as illustrated in FIG. 11. During the movement of passage from one to the other position, illustrated in FIGS. 8 to 11, the reliefs 24 pass through the forks and cause the temporary bending of the arms 20 in the radial direction. This passage produces an audible click and constitutes a hard point during the maneuver which manifests for the user the change of high or low position. In addition, the reliefs 24 hold the button in the high position against the return spring, unless the user acts otherwise.
En référence aux figures 1, 4 et 7, la pipette comporte un crabot 32 de forme générale cylirdπque présentant une nervure périphérique annulaire externe 34 à mi-hauteur environ. Le bouton 8 comporte deux pièces cylindriques 8a et 8b inférieure et supérieure emmanchées à force extérieurement sur le crabot 32 et en appui axial sur la nervure 34. Le bouton 8 est rigidement fixé au crabot. Le crabot présente sur sa face externe, illustrée en détail sur la figure 1 r des reliefs coopérant avec des reliefs complémentaires du bouton pour assurer ces liaisons rigides. Le craoot 32 comporte une denture 36 s' étendant près αe sor borα supérieur, en saillie radiale de sa face interne en direction de l'axe. La pipette comporte un entraîneur 38 présentant une partie supérieure 40 de forme cylindrique munie αe plusieurs dents 42, par exemple au nombre de deux, s' étendant près de son bord supérieur, en saillie radiale de sa face externe en direction opposée a l'axe. Ces deux dents sont aptes a venir en prise avec la denture 36 du crabot lorsqu'elles s'étendent a la même hauteur que celle-ci le long de l'axe 10. L'entraîneur 38 peut être rendu mobile par rapport à la vis de réglage 5. Il s'étend directement en regard de celle-ci radialement. Contrairement à la vis de réglage 5 qui est mobile suivant un mouvement hélicoïdal autour de l'axe 10, l'entraîneur 38 est fixe à coulissement suivant l'axe 10 par rapport au corps de la pipette. Il est bloqué à cette fin en partie supérieure par une entretoise 44 et en partie inférieure par une pièce 46 illustrées à la figure 1. En référence notamment aux figures 5, 6 et 12, l'entraîneur 38 comporte deux pattes principales 48 et deux pattes secondaires 50 s' étendant parallèlement: a l'axe 10 vers le bas à partir de la partie supérieure 40. Les pattes secondaires 50 ont une forme en secteur de cylindre d'axe 10. Elles sont alternées autour de l'axe avec les pattes principales 48. Les pattes principales 48 ont une face externe cylindrique et présentent une face interne plane en saillie radiale de laquelle s'étend une nervure 52 profilée parallèlement à l'axe 10 et à section rectangulaire. L'entraîneur 38 comporte un ressort 54 encerclant extérieurement les quatre pattes 48, 50 et logé dans une encoche externe de celles-ci. Le ressort tend à rapprocher les pattes radialement de l'axe. La vis de réglage 5 est creuse et traversée longitudinalement par la tige de commande 4. Ces deux pièces sont totalement indépendantes dans leur mouvement relatif. La vis de réglage 5 a une forme générale circulaire de révolution. Toutefois, plus précisément, elle présente deux méplats 56 parallèles l'un à l'autre et à l'axe 10 et opposés de part et d'autre de cet axe. Ces méplats s'étendent sur une portion médiane 58 de la vis s' étendant au-dessus d'une portion inférieure filetée 60 de la vis servant au réglage du volume. Ces méplats 56 sont joints l'un à l'autre par des arcs de cercle 61. La vis de réglage présente en outre deux ergots longitudinaux 6 o parallèles à l'axe 10, s' étendant au bord des méplats respectifs de façon à présenter une butée lorsqu'on parcourt circonférentiellement la face externe de la vis 5 à partir des méplats, mais aussi de façon a présenter un arc de cercle ne formant pas une butée a partir des zones cylindriques 61.Referring to Figures 1, 4 and 7, the pipette comprises a dog clutch 32 of general cylindirdπque shape having an external annular peripheral rib 34 at about half height. The button 8 comprises two cylindrical pieces 8a and 8b, lower and upper, force-fitted externally on the dog clutch 32 and in axial support on the rib 34. The button 8 is rigidly fixed to the dog clutch. The sliding sleeve has on its outer surface, illustrated in detail in FIG 1 r reliefs co-operating with complementary reliefs button to make these rigid bonds. The craoot 32 has a toothing 36 extending near the upper boron, projecting radially from its internal face in the direction of the axis. The pipette comprises a driver 38 having an upper part 40 of cylindrical shape provided with several teeth 42, for example two in number, extending near its upper edge, projecting radially from its external face in a direction opposite to the axis . These two teeth are capable of engaging with the teeth 36 of the dog clutch when they extend at the same height as the latter along the axis 10. The driver 38 can be made movable relative to the adjustment screw 5. It extends directly opposite the latter radially. Unlike the adjusting screw 5 which is movable in a helical movement around the axis 10, the driver 38 is fixed to slide along the axis 10 relative to the body of the pipette. It is blocked for this purpose in the upper part by a spacer 44 and in the lower part by a part 46 illustrated in Figure 1. With particular reference to Figures 5, 6 and 12, the coach 38 has two main legs 48 and two legs secondary 50 extending parallel: to the axis 10 downwards from the upper part 40. The secondary legs 50 have a cylinder sector shape with an axis 10. They alternate around the axis with the legs main 48. The main tabs 48 have a cylindrical external face and have a flat internal surface projecting radially from which extends a rib 52 profiled parallel to the axis 10 and of rectangular section. The driver 38 includes a spring 54 externally encircling the four tabs 48, 50 and housed in an external notch thereof. The spring tends to bring the tabs radially from the axis. The adjusting screw 5 is hollow and traversed longitudinally by the control rod 4. These two parts are completely independent in their relative movement. The adjusting screw 5 has a generally circular shape of revolution. However, more specifically, it has two flats 56 parallel to each other and to the axis 10 and opposite on either side of this axis. These flats extend over a middle portion 58 of the screw extending above a threaded lower portion 60 of the screw used for adjusting the volume. These flats 56 are joined to each other by arcs of a circle 61. The adjusting screw also has two longitudinal pins 6 o parallel to the axis 10, extending to the edge of the respective flats so as to present a stop when circumferentially traversing the external face of the screw 5 from the flats, but also so as to present an arc of a circle not forming a stop from the cylindrical zones 61.
Les deux ergots 62 ne sont pas symétriques l'un de l'autre par rapport à l'axe 10 mais le sont par rapport à un plan médian de la vis parallèle aux deux méplats. De plus, les deux ergots 62 ne s'étendent pas exactement en coïncidence en ce qui concerne leur position le long de l'axe 10. Ils se chevauchent sur un certain tronçon. Mais l'un des ergots s'étend plus haut que l'autre alors que ce dernier s'étend vers le bas davantage que le premier. Aussi, les deux ergots sont- ils en chevauchement partiel le long de l'axe 10. La position longitudinale du deuxième ergot, normalement caché sur la figure 6, a toutefois été indiquée par le trait 56. L'entraîneur 38 peut être couplé à la vis 5 en rotation, ou désaccouplé de celle-ci.The two pins 62 are not symmetrical to each other with respect to the axis 10 but are so with respect to a median plane of the screw parallel to the two flats. In addition, the two pins 62 do not extend exactly in coincidence with regard to their position along the axis 10. They overlap over a certain section. But one of the lugs extends higher than the other while the latter extends downwards more than the first. Also, the two lugs are in partial overlap along the axis 10. The longitudinal position of the second lug, normally hidden in FIG. 6, has however been indicated by the line 56. The driver 38 can be coupled to the screw 5 in rotation, or uncoupled from the latter.
Lorsqu'il est couplé, comme sur les figures 12 et 15, l'entraîneur est situé à un niveau de la vis sur lequel se chevauchent les deux ergots 62. Les pattes secondaires 48 sont en appui sur les zones cylindriques 61 dont elles épousent la forme. Elles réalisent avec celles-ci un contact surface contre surface. Les nervures 52 sont en appui radial sur les méplats 56 et en butée sur les ergots 62 respectifs. Le ressort 54 maintient les quatre pattes en appui sur la vis 5 et notamment maintient la prise des nervures sur les ergots. Par conséquent, un mouvement à rotation de l'entraîneur 38 peut être transmis à la vis de réglage 5. Comme l'entraîneur est fixe à coulissement le long de l'axe à la différence de la vis 5, cette rotation produit le coulissement de la vis le long de l'axe, la vis ayant un mouvement hélicoïdal. Les deux pièces sont ainsi couplées à rotation autour de l'axe au moyen de forces de friction et surtout au moyen des ergots et nervures. La transmission du couple a donc lieu même en présence d'un fort couple résistant. Les ergots 62 sont positionnés de sorte qu'au voisinage de chaque position de fin de course haute et basse de la vis de réglage 5, l'ergot qui assure la transmission du mouvement en direction de cette butée s'interrompt, comme illustré sur les figures 14 a 18. Dès lors, sur toute la plage de mouvement restant a parcourir jusqu'à atteindre la position de butée, la transmission du couple ne se fait plus que grâce aux forces de friction des pattes sur la vis. Dans ces conditions, cette transmission n'a lieu que si l'intensité des forces de liaison, et donc l' intensité du couple résistant, est inférieure à une valeur prédéterminée fonction du ressort 54. Cette transmission a néanmoins lieu, de sorte que l'utilisateur peut continuer à manœuvrer (indirectement comme on le verra plus loin) l'entraîneur 38 pour entraîner la vis 5. Dès que la vis 5 arrive en fin de course de réglage, le couple résistant devient infiniment grand et interrompt la liaison par les forces de friction. Maigre l'effet de rappel du ressort 54, les pattes principales 48 s'écartent alors pour quitter les méplats et arriver sur les zones 61 pour suivre la forme de la vis et l'entraîneur 38 tourne seul. La vis de réglage 5 n'est donc pratiquement plus sollicitée et reste immobile. Le filet 60 de la vis 5 est donc protège a l'égard des sollicita ions excessives . Si l'utilisateur veut actionner la vis 5 dans l'autre sens a partir de cette position, il lui suffit d'actionner l'entraîneur 38 dans l'autre sens. Avant moins d'un demi-tour, l'une des nervures 52 rencontre l'autre ergot 62 et les deux pièces sont a nouveau liées a rotation dans l'autre sens. Le même fonctionnement a lieu au voisinage de l'autre extrémité de la course de réglage.When it is coupled, as in FIGS. 12 and 15, the driver is located at a level with the screw on which the two lugs 62 overlap. The secondary tabs 48 are in abutment on the cylindrical zones 61 of which they match the form. They make surface-to-surface contact with them. The ribs 52 are in radial abutment on the flats 56 and in abutment on the respective lugs 62. The spring 54 keeps the four tabs resting on the screw 5 and in particular maintains the grip of the ribs on the pins. Consequently, a rotary movement of the driver 38 can be transmitted to the adjustment screw 5. As the driver is fixed to slide along the axis unlike the screw 5, this rotation produces the sliding of the screw along the axis, the screw having a helical movement. The two parts are thus coupled in rotation about the axis by means of friction forces and especially by means of the pins and ribs. Torque transmission therefore takes place even in the presence of a strong resisting torque. The lugs 62 are positioned so that in the vicinity of each upper and lower end position of the adjusting screw 5, the lug which ensures the transmission of the movement towards this stop is interrupted, as illustrated in the FIGS. 14 to 18. Consequently, over the entire range of movement remaining to be traversed until reaching the stop position, the transmission of the torque only takes place thanks to the friction forces of the tabs on the screw. Under these conditions, this transmission takes place only if the intensity of the bonding forces, and therefore the intensity of the resistive torque, is less than a predetermined value depending on the spring 54. This transmission nevertheless takes place, so that the the user can continue to operate (indirectly as will be seen below) the driver 38 to drive the screw 5. As soon as the screw 5 reaches the end of the adjustment stroke, the resisting torque becomes infinitely large and interrupts the connection by friction forces. Meager the return effect of the spring 54, the main legs 48 then move apart to leave the flats and arrive on the zones 61 to follow the shape of the screw and the driver 38 turns alone. The adjusting screw 5 is therefore practically no longer stressed and remains stationary. The thread 60 of the screw 5 is therefore protected against excessive stress. If the user wants to actuate the screw 5 in the other direction from this position, it suffices to actuate the driver 38 in the other direction. Before less than half a turn, one of the ribs 52 meets the other lug 62 and the two parts are again linked in rotation in the other direction. The same operation takes place in the vicinity of the other end of the adjustment stroke.
On va maintenant décrire le fonctionnement du bouton de réglage 8. La position basse, inactive, verrouillée, du bouton est illustrée aux figures 1, 3 et 4. Les bras 20 sont en prise avec le bouton 8. La tige 4 est donc solidaire en rotation du bouton 8. Dans cette position, les dents 36 du crabot sont hors de prise avec les dents 42 de l'entraîneur 38. Aucun mouvement du boutor 8 n'entraîne donc en rotation l'entraîneur 38 ou la vis 5. Cette position basse du bouton 8 inactive donc les moyens de réglage. Le volume a pipeter ne peut donc pas être modifie volontairement ou involontairement. Les mentions « verrouille » ou « locked » inscrites sur la face externe 26 du bouton 8 apparaissent dans la fenêtre a destination de l'utilisateur. Un ressort de rappel 60 illustré à la figure 1 prenant appui axialement vers le haut sur le coupleur 12 et vers le bas sur le bouton 8 sollicite ce dernier pour le maintenir dans cette position basse. Si l'utilisateur souhaite régler le volume, il fait coulisser le bouton 8 vers le haut à l' encontre du ressort 60 de sorte que les fourches 30 franchissant les reliefs 24 produisent un clic et un point dur. Le bouton est alors dans la position supérieure, active, déverrouillée. Il est maintenu dans cette position par les reliefs 24, sauf action contraire de l'utilisateur. Dans cette position, les dents 36 du crabot sont en prise avec les dents 42 de l'entraîneur 38. Une sollicitation directe du bouton 8 ou du bouton 6 à rotation exercée par l'utilisateur est donc transmise par les dents 36, 42 à l'entraîneur 38, puis à la vis de réglage 5 dans la mesure où celle-ci n'est pas déjà en fin de course pour le sens de réglage souhaite. Lorsque le volume de prélèvement souhaité est réglé, l'utilisateur fait à nouveau coulisser le bouton 8 dans la position basse pour empêcher un déréglage intempestif .We will now describe the operation of the adjustment button 8. The low, inactive, locked position of the button is illustrated in FIGS. 1, 3 and 4. The arms 20 are engaged with the button 8. The rod 4 is therefore secured in rotation of the button 8. In this position, the teeth 36 of the dog clutch are out of engagement with the teeth 42 of the driver 38. No movement of the knob 8 therefore causes the driver 38 or the screw 5 to rotate. This position button 8 low therefore deactivates the adjustment means. The volume to be pipetted cannot therefore be changed voluntarily or involuntarily. The words “locked” or “locked” written on the external face 26 of the button 8 appear in the window intended for the user. A spring of reminder 60 illustrated in FIG. 1 bearing axially upwards on the coupler 12 and downwards on the button 8 urges the latter to maintain it in this low position. If the user wishes to adjust the volume, he slides the button 8 upwards against the spring 60 so that the forks 30 crossing the reliefs 24 produce a click and a hard point. The button is then in the upper, active, unlocked position. It is held in this position by the reliefs 24, unless the user decides otherwise. In this position, the teeth 36 of the dog clutch are engaged with the teeth 42 of the driver 38. A direct stress on the button 8 or on the rotary button 6 exerted by the user is therefore transmitted by the teeth 36, 42 to the 'coach 38, then to the adjusting screw 5 insofar as the latter is not already at the end of its travel for the desired direction of adjustment. When the desired sampling volume is adjusted, the user again slides the button 8 in the low position to prevent inadvertent adjustment.
On remarque, dans la pipette qui vient d'être décrite, que le serrage de l'entraîneur 38 sur la vis 5 et donc leur embrayage ou débrayage se font automatiquement et non par l'action directe de l'utilisateur sur ces pièces. De plus, l'utilisateur n'actionne jamais directement la vis de réglage 5.It is noted, in the pipette which has just been described, that the tightening of the driver 38 on the screw 5 and therefore their engagement or disengagement are done automatically and not by the direct action of the user on these parts. In addition, the user never directly actuates the adjusting screw 5.
On pourra prévoir que des deux éléments 5, 38, celui qui est deformable pour interrompre leur liaison est la vis 5. On a illustré à la figure 19 une variante de réalisation dans laquelle les éléments analogues ont des références numériques augmentées de 100. La tige 104 n'a pas été illustrée. Dans cette variante, les nervures 152 ont un profil en « V » à pointe arrondie. Les méplats 156 sont remplacés par des rainures 156 à profil en « V » de même angle que celui des nervures pour permettre l'entraînement de la vis 105 par l'entraîneur 138. Au voisinage des positions de butée, les rainures respectives s'élargissent en accentuant l'inclinaison de l'une de leurs deux faces. Cette face forme une rampe. La pipette est agencée de sorte que, lorsque la position de fin de course est atteinte, la force de serrage du ressort est insuffisante pour maintenir les nervures 152 dans les rainures 156. La rampe provoque alors la sortie des nervures hors des rainures et l'écartement des pattes principales 148, de sorte que l'entraîneur n'entraîne plus la vis et continue à tourner seul.Provision may be made for the two elements 5, 38, the one which is deformable to interrupt their connection is the screw 5. FIG. 19 illustrates an alternative embodiment in which the analogous elements have numerical references increased by 100. The rod 104 has not been illustrated. In this variant, the ribs 152 have a “V” profile with rounded tip. The flats 156 are replaced by grooves 156 with a “V” profile of the same angle as that of the ribs to allow the driving of the screw 105 by the driver 138. In the vicinity of the stop positions, the respective grooves widen. by accentuating the inclination of one of their two faces. This face forms a ramp. The pipette is arranged so that, when the end position is reached, the spring clamping force is insufficient to hold the ribs 152 in the grooves 156. The ramp then causes the ribs to exit from the grooves and the spacing of the main legs 148, so that the driver no longer drives the screw and continues to rotate alone.
La pipette pourra comprendre des moyens électroniques d'affichage (par exemple à cristaux liquides) d'un paramètre relatif au fonctionnement de la pipette. Par exemple, ces moyens pourront indiquer en permanence l'état verrouillé ou déverrouillé du bouton 8. The pipette may include electronic display means (for example with liquid crystal) of a parameter relating to the operation of the pipette. For example, these means may permanently indicate the locked or unlocked state of the button 8.

Claims

REVENDICATIONS
1. Pipette de prélèvement comportant des moyens de réglage (6, 12, 8, 38, 5) d'un volume de liquide a prélever comprenant au moins un organe de commande de réglage, la pipette comprenant un élément de blocage (8) mobile entre une position inactive dans laquelle il rend les moyens de réglage inaptes au réglage et une position active dans laquelle il rend les moyens de réglage aptes au réglage caractérisée en ce que l'élément de blocage est l'organe de commande de réglage .1. Sampling pipette comprising adjustment means (6, 12, 8, 38, 5) of a volume of liquid to be sampled comprising at least one adjustment control member, the pipette comprising a movable blocking element (8) between an inactive position in which it renders the adjustment means unsuitable for adjustment and an active position in which it renders the adjustment means suitable for adjustment characterized in that the locking element is the adjustment control member.
2. Pipette selon la revendication 1, caractérisée en ce que l'élément de blocage (8) est mobile a coulissement entre les deux positions.2. Pipette according to claim 1, characterized in that the locking element (8) is movable by sliding between the two positions.
3. Pipette selon la revendication 1 ou 2, caractérisée en ce que l'élément de blocage ι8) s' étend à l'intérieur d'un corps de la pipette.3. Pipette according to claim 1 or 2, characterized in that the blocking element ι8) extends inside a body of the pipette.
4. Pipette selon l'une quelconque des revendications 1 à 3, caractérisée en ce qu'elle est agencée de sorte que l'élément de blocage (8) est apte à transmettre un mouvement de réglage a un organe 38; des moyens de réglage en position active, et est inapte à cette transmission en position inactive. 4. Pipette according to any one of claims 1 to 3, characterized in that it is arranged so that the locking element (8) is capable of transmitting an adjustment movement to a member 38; adjustment means in the active position, and is unsuitable for this transmission in the inactive position.
5. Pipette selon l'une quelconque des revendications 1 à 4, caractérisée en ce qu'el±e est agencée de sorte que l'élément de blocage (8) est apte à transmettre un mouvement de l'un (12) à l'autre (38; de deux organes des moyens de réglage autres que l'élément de blocage en position active et est inapte a cette transmission en position inactive. 5. Pipette according to any one of claims 1 to 4, characterized in that el ± e is arranged so that the locking element (8) is capable of transmitting a movement from one (12) to the 'other (38; two organs of the adjusting means other than the locking element in the active position and is unsuitable for this transmission in the inactive position.
6. Pipette selon l'une quelconque des revendications 4 a 5, caractérisée en ce que le mouvement est une rotation.6. Pipette according to any one of claims 4 to 5, characterized in that the movement is a rotation.
7. Pipette selon l'une quelconque des revendications 1 a 6, caractérise en ce que les moyens de réglage comprennent deux organes (8, 38) agences pour être en crabotage mutuel lorsque l'élément de blocage (8) est en position active et pour être desengages l'un de l'autre lorsque l'élément de blocage est en position inactive.7. Pipette according to any one of claims 1 to 6, characterized in that the adjustment means comprise two members (8, 38) agencies to be in mutual engagement when the locking element (8) is in the active position and to be disengaged from each other when the locking element is in the inactive position.
8. Pipette selon l'une quelconque des revendications 1 a 7, caractérisée en ce que la pipette comporte deux organes (6, 8) de commande de réglage.8. Pipette according to any one of claims 1 to 7, characterized in that the pipette comprises two members (6, 8) for adjusting control.
9. Pipette selon l'une quelconque des revendications 1 a 8, caractérisée en ce qu'elle comporte un bouton (6) de commande de prélèvement formant un organe de commande de réglage.9. Pipette according to any one of claims 1 to 8, characterized in that it comprises a button (6) for sampling control forming an adjustment control member.
10. Pipette selon l'une quelconque des revendications 1 a 9, caractérisée en ce qu'elle comporte des moyens de rappel ( 60 "i de l' élément de blocage (8) dans la position inactive.10. A pipette according to any one of claims 1 to 9, characterized in that it comprises return means (60 "i of the n blocking eleme t (8) in the inactive position.
11. Pipette selon la revendication 10, caractérisée en ce qu'elle comporte des moyens (24) pour maintenir l'élément de blocage (p) dar r~ la position active a l'encontre des moyens de rappel (60) .11. Pipette according to claim 10, characterized in that it comprises means (24) for holding the locking element ( p ) dar r ~ the active position against the return means (60).
12. Pipette selon l'une quelconque des revendications 1 a 11, caractérisée en ce qu'elle est agencée de sorte que l'élément de blocage est apte a passer de la position active a la position inactive avec franchissement d'un point dur. 12. Pipette according to any one of claims 1 to 11, characterized in that it is arranged so that the blocking element is capable of passing from the active position to the inactive position with the crossing of a hard point.
13. Pipette selon l'une quelconque des revendications 1 à 12 , caractérisée en ce que les moyens de réglage comportent un organe moteur (38) et un organe récepteur (5) apte à être entraîné par l'organe moteur au moyen d'une liaison par complémentarité de forme, l'un (38) des organes moteur et récepteur étant deformable de façon à interrompre la liaison lorsqu'il est soumis à une sollicitation d'intensité supérieure à une intensité prédéterminée. 13. Pipette according to any one of claims 1 to 12, characterized in that the adjustment means comprise a drive member (38) and a receiver member (5) capable of being driven by the drive member by means of a link by complementarity of form, one (38) of the motor and receiver members being deformable so as to interrupt the link when it is subjected to a stress of intensity greater than a predetermined intensity.
EP01921520A 2000-04-07 2001-04-09 Pipette provided with sampling volume adjusting means Expired - Lifetime EP1268067B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK01921520T DK1268067T3 (en) 2001-04-09 2001-04-09 Liquid withdrawal pipette provided with means for controlling the withdrawal volume

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0004473A FR2807343B1 (en) 2000-04-07 2000-04-07 COLLECTION PIPETTE PROVIDED WITH MEANS FOR ADJUSTING THE VOLUME TO BE COLLECTED
FR0004473 2000-04-07
PCT/FR2001/001068 WO2001076748A1 (en) 2000-04-07 2001-04-09 Pipette provided with sampled volume adjusting means

Publications (2)

Publication Number Publication Date
EP1268067A1 true EP1268067A1 (en) 2003-01-02
EP1268067B1 EP1268067B1 (en) 2004-06-30

Family

ID=8848995

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01921520A Expired - Lifetime EP1268067B1 (en) 2000-04-07 2001-04-09 Pipette provided with sampling volume adjusting means

Country Status (15)

Country Link
US (1) US6959616B2 (en)
EP (1) EP1268067B1 (en)
JP (1) JP4728554B2 (en)
KR (1) KR100687591B1 (en)
CN (2) CN1182921C (en)
AT (1) ATE270150T1 (en)
AU (2) AU2001248498B2 (en)
CA (1) CA2404717C (en)
DE (1) DE60104099T2 (en)
ES (1) ES2221894T3 (en)
FR (1) FR2807343B1 (en)
MX (1) MXPA02009882A (en)
PT (1) PT1268067E (en)
RU (1) RU2274489C2 (en)
WO (1) WO2001076748A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6959616B2 (en) 2000-04-07 2005-11-01 Gilson S.A.S. Pipette provided with sampled volume adjusting means
US6994828B2 (en) 2000-04-07 2006-02-07 Gilson S.A.S. Liquid sample pipette with tip ejecting mechanism
US6997067B2 (en) 2000-04-07 2006-02-14 Gilson S.A.S. Liquid sample pipette with detachable ejector
US7264779B2 (en) 2000-04-07 2007-09-04 Gilson S.A.S. Pipette with tip ejector

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE365075T1 (en) * 2003-08-19 2007-07-15 Socorex Isba S A MECHANICAL PISTON PIPETTE
EP1541235A1 (en) * 2003-11-27 2005-06-15 Gilson S.A.S. Method of correcting the display of the volume in a pipette
FR2862888B1 (en) * 2003-11-27 2006-07-07 Gilson Sas METHOD FOR DISPLAYING A VALUE OF A VOLUME OF A LIQUID SAMPLE TO BE TAKEN WITH A PIPETTE, WITH IMPROVED PRECISION
US7976793B2 (en) * 2003-11-27 2011-07-12 Gilson S.A.S. Electronic pipette
FR2867397B1 (en) * 2004-03-09 2006-06-30 Gilson Sas METHOD OF DISPLAYING A VALUE OF A VOLUME OF A LIQUID SAMPLE TO BE TAKEN WITH A PIPETTE, WITH IMPROVED PRECISION
TW200809202A (en) * 2006-08-04 2008-02-16 Arise Biotech Corp Electric micro-quantum injector capable of a real time reaction for push-action of the arms
US7794664B2 (en) 2006-11-16 2010-09-14 Idexx Laboratories, Inc. Pipette tip
PL211690B1 (en) * 2007-11-23 2012-06-29 Pz Htl Społka Akcyjna Pipette with preset volume of collected liquid
DE102008048252A1 (en) * 2008-09-12 2010-04-15 Eppendorf Ag pipetting
FI123652B (en) 2011-10-20 2013-08-30 Thermo Fisher Scientific Oy Lockable pipette
FI125309B (en) * 2012-03-30 2015-08-31 Sartorius Biohit Liquid Handling Oy Steering wheel for pipette
KR102282274B1 (en) * 2015-03-26 2021-07-28 가부시키가이샤 에이 앤 디 Overload prevention mechanism
EP3112026B1 (en) * 2015-06-30 2018-03-14 Sartorius Biohit Liquid Handling Oy Pipette with a tip removal mechanism, a method for removing a tip, and a method for pipetting
CN106586555B (en) * 2016-12-28 2022-03-29 上海原能细胞生物低温设备有限公司 Variable capacity suction device
US10744498B2 (en) * 2017-09-19 2020-08-18 Mettler-Toledo Rainin, LLC Pipette quickset volume adjustment mechanism
FR3080050B1 (en) * 2018-04-17 2020-03-27 Gilson Sas DEVICE FOR LOCKING A VOLUME ADJUSTMENT SCREW FOR A PIPETTING SYSTEM
KR102427246B1 (en) * 2020-09-18 2022-07-29 바디텍메드(주) A mini pipette

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4472E (en) 1904-10-01 1905-08-26 Emile Truel Packing to be applied to piston rods and positioning device
FR4475E (en) 1904-11-15 1905-08-26 Louis Bleriot Lantern holder for automobiles
DE1009969B (en) 1956-02-17 1957-06-06 Montblanc Simplo Gmbh Writing instrument with longitudinally adjustable writing tip holder
US3604267A (en) * 1969-01-15 1971-09-14 Beckman Instruments Inc Sample injection apparatus
US3766785A (en) * 1971-05-17 1973-10-23 Analytical Prod Automatic pipette
US3827305A (en) * 1972-10-24 1974-08-06 R Gilson Adjustable pipette
DE2319175A1 (en) * 1973-04-16 1974-10-31 Oxford Lab DETAIL PISTON PIPETTE
FR2287941A1 (en) * 1974-10-15 1976-05-14 Marteau D Autry Eric DEVICE FOR EJECTING THE REMOVABLE TIP OF A PIPETTE
US4009611A (en) * 1976-05-13 1977-03-01 Oxford Laboratories Inc. Hand-held micropipettor with improved pipette tip ejector
GB1597336A (en) * 1977-06-15 1981-09-03 Sherwood Medical Ind Inc Micropipettors
US4096751A (en) * 1977-06-15 1978-06-27 Oxford Laboratories Inc. Hand-held micropipettor with fluid transfer volume adjustment mechanism
US4369665A (en) * 1978-01-11 1983-01-25 Indicon Inc. Manually holdable automatic pipette
US4164870A (en) * 1978-04-10 1979-08-21 Medical Laboratory Automation, Inc. Pipettes
FI76710B (en) * 1978-09-08 1988-08-31 Osmo Antero Suovaniemi Pipette.
GB2029723B (en) 1978-09-12 1982-12-01 Lee T Adjustable volume pipetting device
FI60138C (en) * 1979-03-23 1981-12-10 Suovaniemi Finnpipette pipette
DE2954504A1 (en) 1979-08-31 1986-09-11 Kommandiittiyhtiö Finnpipette Osmo A. Suovaniemi, Helsinki Pipette with two knobs - one for use in filling operation and other with longer stroke for discharging-operation
US4442722A (en) * 1982-02-23 1984-04-17 Beckman Instruments Inc. Plunger operated pipet
CN1013348B (en) * 1986-10-28 1991-07-31 苏联科学院生物仪器制造科研生产联合公司 Suction tube
JP2648944B2 (en) * 1988-10-20 1997-09-03 東亜医用電子株式会社 Fluid circuit unit
DE3875117D1 (en) * 1988-10-21 1992-11-05 Eppendorf Geraetebau Netheler PIPETTING DEVICE.
AU3092592A (en) 1991-12-13 1993-07-19 John Poulten Limited Pipetter
FI921765A0 (en) 1992-04-21 1992-04-21 Labsystems Oy MED EN SPETSAVLAEGSNARE FOERSEDD PIPETT.
US5320810A (en) * 1992-05-13 1994-06-14 Integrated Instrument Services, Inc. Pipette with an axially stationary volume adjusting wheel
FR2696110B1 (en) * 1992-09-28 1994-12-09 Gilson Medical Electronics Sa Improvement to a pick-up and distribution pole for adjustable volumes of liquids.
DE4339143A1 (en) 1993-11-16 1995-05-18 Jenoptron Ges Fuer Optoelektro Automatic sample dispensing appts.
FR2723700B1 (en) * 1994-08-16 1996-11-15 Marteau D Autry Eric PIPETTE FOR DISPENSING SUCCESSIVE LIQUID VOLUMES
DE9415847U1 (en) 1994-09-30 1994-12-08 Ritter Ralf Repeater pipette
FI951766A0 (en) * 1995-04-12 1995-04-12 Labsystems Oy Faspipett
US5614153A (en) * 1995-05-26 1997-03-25 Rainin Instrument Co., Inc. Pipette tip ejector
US5650124A (en) * 1995-07-24 1997-07-22 Gilson; Warren E. Adjustable pipette
US5849248A (en) * 1996-03-05 1998-12-15 Rainin Instrument Co., Inc. Adjustable volume pipette with improved volume adjustment lock mechanism
US5792424A (en) * 1996-03-05 1998-08-11 Rainin Instrument Co., Inc. Manual pipette with delayed-action home position latch
FI961649A0 (en) * 1996-04-15 1996-04-15 Labsystems Oy Spaerrpipett
US5983733A (en) * 1996-11-15 1999-11-16 Hamilton Company Manual pipette
US5958343A (en) * 1997-12-29 1999-09-28 Astle; Thomas W. Small volume pipettor
US6295880B1 (en) 1999-12-08 2001-10-02 Warren E. Gilson Adjustable pipette
US6532837B1 (en) * 2000-02-03 2003-03-18 Rainin Instrument, Llc Pipette device with tip ejector utilizing stored energy
FR2807343B1 (en) 2000-04-07 2002-12-06 Gilson Sa COLLECTION PIPETTE PROVIDED WITH MEANS FOR ADJUSTING THE VOLUME TO BE COLLECTED
FR2807345B1 (en) 2000-04-07 2002-07-12 Gilson Sa SIMPLIFIED DISASSEMBLY PIPETTE
FR2807342B1 (en) 2000-04-07 2002-07-12 Gilson Sa CONCEAL EJECTOR PIPETTE
FR2807339B1 (en) 2000-04-07 2002-12-13 Gilson Sa PIPETTE FOR TAKING LIQUID SAMPLES WITH ADJUSTABLE EJECTOR
FR2807341B1 (en) 2000-04-07 2002-07-12 Gilson Sa PIPETTE FOR COLLECTING LIQUID SAMPLES WITH REMOVABLE EJECTOR
FR2807340B1 (en) 2000-04-07 2002-12-06 Gilson Sa PIPETTE FOR TAKING LIQUID SAMPLES WITH CONE EJECTOR MECHANISM
FR2807558B1 (en) 2000-04-07 2004-04-02 Gilson Sa PIPETTE FOR SAMPLING PROVIDED WITH MEANS FOR DISPLAYING A PARAMETER OF THE PIPETTE
FIU20010274U0 (en) * 2001-07-06 2001-07-06 Biohit Oyj The suction device
US6532877B1 (en) * 2002-01-22 2003-03-18 Stanrail Corporation Railroad car roof panel and skylight assembly

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0176748A1 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6959616B2 (en) 2000-04-07 2005-11-01 Gilson S.A.S. Pipette provided with sampled volume adjusting means
US6994828B2 (en) 2000-04-07 2006-02-07 Gilson S.A.S. Liquid sample pipette with tip ejecting mechanism
US6997067B2 (en) 2000-04-07 2006-02-14 Gilson S.A.S. Liquid sample pipette with detachable ejector
US7264779B2 (en) 2000-04-07 2007-09-04 Gilson S.A.S. Pipette with tip ejector

Also Published As

Publication number Publication date
CA2404717C (en) 2009-11-10
DE60104099T2 (en) 2005-06-30
CN1607382A (en) 2005-04-20
FR2807343A1 (en) 2001-10-12
KR100687591B1 (en) 2007-02-28
JP4728554B2 (en) 2011-07-20
US20040035228A1 (en) 2004-02-26
ES2221894T3 (en) 2005-01-16
AU4849801A (en) 2001-10-23
US6959616B2 (en) 2005-11-01
CN1182921C (en) 2005-01-05
KR20020088433A (en) 2002-11-27
CN1422182A (en) 2003-06-04
CN1607382B (en) 2013-03-27
AU2001248498B2 (en) 2005-06-16
RU2274489C2 (en) 2006-04-20
FR2807343B1 (en) 2002-12-06
MXPA02009882A (en) 2004-05-05
DE60104099D1 (en) 2004-08-05
EP1268067B1 (en) 2004-06-30
ATE270150T1 (en) 2004-07-15
PT1268067E (en) 2004-11-30
WO2001076748A1 (en) 2001-10-18
JP2003530551A (en) 2003-10-14
CA2404717A1 (en) 2001-10-18

Similar Documents

Publication Publication Date Title
EP1268067A1 (en) Pipette provided with sampled volume adjusting means
EP2062610B1 (en) Device for inflating a small balloon
WO2008122716A1 (en) Tightening device with swivelling handling arm and applicance including such a device
EP3349901A1 (en) Sampling pipette comprising a control member with double function for ejecting a cone and unlocking the system for volume adjustment
EP2762212A1 (en) Removable stick tip
EP0723086A1 (en) Screw with a separable head and screwing tool for such a screw
FR2594404A1 (en) LEVER DEVICE FOR CHANGING BICYCLE SPEED
FR2807958A1 (en) SLEEVE FOR EXTRACTION TOOL, CORRESPONDING EXTRACTION TOOL, AND CORRESPONDING EXTRACTION METHOD
CH703400A2 (en) Watch case, has bezel, retaining ring and unit to define unstable positions of bezel such that bezel is displaced with respect to ring till bezel is brought back to disassembling position only when bezel is blocked on one unstable position
EP1375072B1 (en) Torque tool, especially wrench, with snap means for adjusting the torque
WO2001076747A1 (en) Pipette with simplified disassembly
FR2885312A1 (en) RATCHET
EP3749456B1 (en) Device for locking a volume adjustment screw for a pipetting system
FR2807344A1 (en) Sampling pipette with mechanism controlling volume extracted has clutch disengaging automatically when subjected to excessive force
FR2705079A1 (en) Operating device for cycle derailleur and brake
FR2536689A1 (en) Screwdriver comprising a mechanism for coupling its shank
EP0978671A1 (en) Parking brake control device combined with the gearbox control lever
EP2631162B1 (en) Sequential gearshift lever for bicycle
CA2542879A1 (en) Mechanical pencil
FR2622481A1 (en) Liquid applicator, in particular for nail varnish
EP1691111B1 (en) Gear change Control device in a transmission of a vehice
EP2349621B1 (en) Bow saw mounting and corresponding bow saw
CH190466A (en) Watch winder.
FR2816862A1 (en) Coupling device of rotating part to tool comprises base body with coupling head and axial groove in which locking component is located
FR2948590A1 (en) ROLLED TOOL WITH IMPROVED INVERSION

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20021026

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GILSON SAS

GRAH Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOS IGRA

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RTI1 Title (correction)

Free format text: PIPETTE PROVIDED WITH SAMPLING VOLUME ADJUSTING MEANS

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20040630

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: MICHELI & CIE INGENIEURS-CONSEILS

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: FRENCH

REF Corresponds to:

Ref document number: 60104099

Country of ref document: DE

Date of ref document: 20040805

Kind code of ref document: P

GBT Gb: translation of ep patent filed (gb section 77(6)(a)/1977)

Effective date: 20040812

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20040930

REG Reference to a national code

Ref country code: DK

Ref legal event code: T3

REG Reference to a national code

Ref country code: PT

Ref legal event code: SC4A

Free format text: AVAILABILITY OF NATIONAL TRANSLATION

Effective date: 20040930

LTIE Lt: invalidation of european patent or patent extension

Effective date: 20040630

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2221894

Country of ref document: ES

Kind code of ref document: T3

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20050409

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20050430

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20050331

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DK

Payment date: 20090415

Year of fee payment: 9

Ref country code: IE

Payment date: 20090421

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: AT

Payment date: 20090416

Year of fee payment: 9

Ref country code: LU

Payment date: 20090414

Year of fee payment: 9

Ref country code: NL

Payment date: 20090415

Year of fee payment: 9

Ref country code: PT

Payment date: 20090402

Year of fee payment: 9

Ref country code: SE

Payment date: 20090416

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 20090415

Year of fee payment: 9

BERE Be: lapsed

Owner name: *GILSON SAS

Effective date: 20100430

REG Reference to a national code

Ref country code: NL

Ref legal event code: V1

Effective date: 20101101

EUG Se: european patent has lapsed
REG Reference to a national code

Ref country code: DK

Ref legal event code: EBP

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100409

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20101101

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100409

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20101011

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100503

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100410

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100409

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FI

Payment date: 20170323

Year of fee payment: 17

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20170420

Year of fee payment: 17

Ref country code: DE

Payment date: 20170412

Year of fee payment: 17

Ref country code: CH

Payment date: 20170424

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20170411

Year of fee payment: 17

Ref country code: ES

Payment date: 20170508

Year of fee payment: 17

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 18

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 60104099

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20180409

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180409

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20181101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180409

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180430

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180409

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20190911

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180410

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20200430

Year of fee payment: 20