EP1230394A4 - Vektortransduktion hematopoietischer stammzellen mittels lentivirus - Google Patents
Vektortransduktion hematopoietischer stammzellen mittels lentivirusInfo
- Publication number
- EP1230394A4 EP1230394A4 EP00978485A EP00978485A EP1230394A4 EP 1230394 A4 EP1230394 A4 EP 1230394A4 EP 00978485 A EP00978485 A EP 00978485A EP 00978485 A EP00978485 A EP 00978485A EP 1230394 A4 EP1230394 A4 EP 1230394A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- stem cells
- hematopoietic stem
- lentiviral vector
- vector transduction
- transduction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16045—Special targeting system for viral vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16462599P | 1999-11-10 | 1999-11-10 | |
US164625P | 1999-11-10 | ||
PCT/US2000/030882 WO2001034843A1 (en) | 1999-11-10 | 2000-11-10 | Lentiviral vector transduction of hematopoietic stem cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1230394A1 EP1230394A1 (de) | 2002-08-14 |
EP1230394A4 true EP1230394A4 (de) | 2002-12-18 |
Family
ID=22595350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00978485A Withdrawn EP1230394A4 (de) | 1999-11-10 | 2000-11-10 | Vektortransduktion hematopoietischer stammzellen mittels lentivirus |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1230394A4 (de) |
JP (1) | JP2003517301A (de) |
AU (1) | AU784988B2 (de) |
CA (1) | CA2391129A1 (de) |
WO (1) | WO2001034843A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7575924B2 (en) | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
IL160132A0 (en) | 2001-08-02 | 2004-06-20 | Inst Clayton De La Rech | Methods and compositions relating to improved lentiviral vector production systems |
EP1438075A4 (de) | 2001-10-02 | 2006-04-19 | Inst Clayton De La Rech | Verfahren und zusammensetzungen in verbindung mit lentiviralen vektoren mit begrenzter expression und ihre anwendungen |
DE60331297D1 (de) | 2002-03-07 | 2010-04-01 | Univ Delaware | Verfahren zur verstärkung der oligonucleotid-vermittelten nucleinsäuresequenzänderung unter verwendung von zusammensetzungen mit einem hydroxyharnstoff |
SG190997A1 (en) | 2010-12-09 | 2013-07-31 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
EP2661489A4 (de) * | 2011-01-03 | 2014-09-10 | Bluebird Bio Inc | Verfahren zur verstärkung der abgabe gen-transduzierter zellen |
UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
DK3129470T3 (da) | 2014-04-07 | 2021-07-05 | Novartis Ag | Behandling af cancer ved anvendelse af anti-CD19-kimær antigenreceptor |
WO2015183885A1 (en) * | 2014-05-27 | 2015-12-03 | Dana-Farber Cancer Institute, Inc. | Methods and compositions for perturbing gene expression in hematopoietic stem cell lineages in vivo |
HUE059218T2 (hu) | 2015-04-08 | 2022-11-28 | Novartis Ag | CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel |
CN110114077A (zh) * | 2016-09-13 | 2019-08-09 | 中央研究院 | 藉移植增加寿命及/或治疗细胞增殖疾病的方法 |
TW202340473A (zh) | 2016-10-07 | 2023-10-16 | 瑞士商諾華公司 | 利用嵌合抗原受體之癌症治療 |
US11597917B2 (en) | 2017-07-06 | 2023-03-07 | The Medical College Of Wisconsin, Inc. | In vitro and in vivo enrichment strategy targeting lymphocytes derived from vector transduced HSCs for therapy of disorders |
-
2000
- 2000-11-10 JP JP2001536768A patent/JP2003517301A/ja active Pending
- 2000-11-10 CA CA002391129A patent/CA2391129A1/en not_active Abandoned
- 2000-11-10 EP EP00978485A patent/EP1230394A4/de not_active Withdrawn
- 2000-11-10 AU AU15944/01A patent/AU784988B2/en not_active Expired - Fee Related
- 2000-11-10 WO PCT/US2000/030882 patent/WO2001034843A1/en not_active Application Discontinuation
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO0134843A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1230394A1 (de) | 2002-08-14 |
CA2391129A1 (en) | 2001-05-17 |
WO2001034843A1 (en) | 2001-05-17 |
AU1594401A (en) | 2001-06-06 |
AU784988B2 (en) | 2006-08-17 |
JP2003517301A (ja) | 2003-05-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020610 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20021107 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 12N 15/11 A, 7C 12N 15/63 B, 7C 12N 15/85 B, 7C 12N 15/86 B, 7C 12Q 1/68 B, 7A 61K 48/00 B, 7A 61K 35/00 B, 7C 07H 21/04 B |
|
17Q | First examination report despatched |
Effective date: 20040524 |
|
17Q | First examination report despatched |
Effective date: 20040524 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20070116 |