EP1210583A4 - Procedes in situ de mesure de la liberation d'une substance a partir d'une forme posologique - Google Patents

Procedes in situ de mesure de la liberation d'une substance a partir d'une forme posologique

Info

Publication number
EP1210583A4
EP1210583A4 EP00961420A EP00961420A EP1210583A4 EP 1210583 A4 EP1210583 A4 EP 1210583A4 EP 00961420 A EP00961420 A EP 00961420A EP 00961420 A EP00961420 A EP 00961420A EP 1210583 A4 EP1210583 A4 EP 1210583A4
Authority
EP
European Patent Office
Prior art keywords
substance
release
measuring
dosage form
situ methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00961420A
Other languages
German (de)
English (en)
Other versions
EP1210583A1 (fr
Inventor
Philip Palermo
Kevin C Bynum
John Pocreva
Bud Pine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delphian Technology Inc
Original Assignee
Delphian Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delphian Technology Inc filed Critical Delphian Technology Inc
Publication of EP1210583A1 publication Critical patent/EP1210583A1/fr
Publication of EP1210583A4 publication Critical patent/EP1210583A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/42Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G01J3/433Modulation spectrometry; Derivative spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • G01N21/8507Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/006Dissolution of tablets or the like
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • G01N2021/651Cuvettes therefore
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • G01N21/8507Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • G01N2021/8514Probe photometers, i.e. with optical measuring part dipped into fluid sample with immersed mirror
    • G01N2021/8521Probe photometers, i.e. with optical measuring part dipped into fluid sample with immersed mirror with a combination mirror cell-cuvette
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • G01N21/8507Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • G01N2021/8528Immerged light conductor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP00961420A 1999-08-30 2000-08-30 Procedes in situ de mesure de la liberation d'une substance a partir d'une forme posologique Withdrawn EP1210583A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15144399P 1999-08-30 1999-08-30
US151443P 1999-08-30
PCT/US2000/023800 WO2001016582A1 (fr) 1999-08-30 2000-08-30 Procedes in situ de mesure de la liberation d'une substance a partir d'une forme posologique

Publications (2)

Publication Number Publication Date
EP1210583A1 EP1210583A1 (fr) 2002-06-05
EP1210583A4 true EP1210583A4 (fr) 2004-08-11

Family

ID=22538787

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00961420A Withdrawn EP1210583A4 (fr) 1999-08-30 2000-08-30 Procedes in situ de mesure de la liberation d'une substance a partir d'une forme posologique

Country Status (5)

Country Link
EP (1) EP1210583A4 (fr)
JP (1) JP2003508748A (fr)
AU (1) AU7337500A (fr)
CA (1) CA2383906A1 (fr)
WO (1) WO2001016582A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077616A1 (fr) * 2001-03-27 2002-10-03 Euro-Celtique, S.A. Dispositif a cristal atr
US7620576B1 (en) 2003-01-21 2009-11-17 Trading Technologies International, Inc. Method and apparatus for providing order queue information
US7024955B2 (en) 2003-03-01 2006-04-11 Symyx Technologies, Inc. Methods and systems for dissolution testing
US7809628B1 (en) 2003-05-30 2010-10-05 Trading Technologies International Inc. System and method for estimating order position
JP2005172779A (ja) * 2003-12-10 2005-06-30 Semiconductor Res Found 電磁波を照射してバクテリア、ウィルスおよび毒性物質を測定する方法および装置
GB0524225D0 (en) * 2005-11-29 2006-01-04 Amersham Biosciences Ab Methods and apparatus for detecting and measuring the concentration of a substance in a solution
JP2009063335A (ja) * 2007-09-05 2009-03-26 Fujifilm Corp 生理活性物質と被験物質との相互作用の測定方法
RU2505798C2 (ru) 2008-04-04 2014-01-27 Колгейт-Палмолив Компани Анализ субстратов, на которые нанесены агенты
JP2009075134A (ja) * 2009-01-05 2009-04-09 Junichi Nishizawa 細菌又は毒性物質の同定装置
JP5773914B2 (ja) * 2011-03-11 2015-09-02 ディステック,インコーポレーテッド 中央制御されたモジュール式のモーター式試験
CN102721796A (zh) * 2012-06-27 2012-10-10 浙江省中医药研究院 一种模拟药物局部释药行为的实验装置及其应用
JP6635363B2 (ja) * 2014-10-24 2020-01-22 京都府公立大学法人 腫瘍部位の判別のための方法、腫瘍部位の判別装置
WO2016079797A1 (fr) * 2014-11-18 2016-05-26 日本メクトロン株式会社 Sonde de mesure de concentration en ligne et système de mesure de concentration
CN109975274B (zh) * 2019-04-16 2024-01-23 北京科技大学 一种高炉铁水硅含量在线快速检测装置
US20230384158A1 (en) * 2020-10-26 2023-11-30 Sony Group Corporation Information processing device, information processing method, and program
CN112816446B (zh) * 2020-12-24 2022-02-01 四川长虹电器股份有限公司 一种基于荧光光谱检测荧光轮粉体衰变的方法
CA3223357A1 (fr) * 2021-07-12 2023-01-19 Brigitte Elisa Anna Burm Quantification de substance amelioree dans des melanges complexes
CN117783459B (zh) * 2024-02-28 2024-05-07 沈阳科惠生物医药科技有限公司 一种药物的溶出曲线测定方法及系统

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5070874A (en) * 1990-01-30 1991-12-10 Biocontrol Technology, Inc. Non-invasive determination of glucose concentration in body of patients
WO1997046860A2 (fr) * 1996-06-04 1997-12-11 Euro-Celtique, S.A. Ameliorations apportees a des systemes de detection et a des procedes de prediction de la courbe de dissolution d'un medicament d'une forme galenique pharmaceutique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335438A (en) * 1980-04-17 1982-06-15 Smolen Victor F Method and apparatus for automatic dissolution testing of products
US4740709A (en) * 1986-04-10 1988-04-26 The United States Of America As Represented By The Department Of Health And Human Services Method of sensing fluid properties independent of bubble concentrations
EP0746750B1 (fr) * 1994-02-25 1998-06-03 Distek Inc. Appareil pour mesurer la dissolution
US5679954A (en) * 1994-11-14 1997-10-21 Soloman; Sabrie Non-destructive identification of tablet and tablet dissolution by means of infared spectroscopy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5070874A (en) * 1990-01-30 1991-12-10 Biocontrol Technology, Inc. Non-invasive determination of glucose concentration in body of patients
WO1997046860A2 (fr) * 1996-06-04 1997-12-11 Euro-Celtique, S.A. Ameliorations apportees a des systemes de detection et a des procedes de prediction de la courbe de dissolution d'un medicament d'une forme galenique pharmaceutique

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CANETE F ET AL: "LIQUID-LIQUID EXTRACTION IN CONTINUOUS FLOW SYSTEMS WITHOUT PHASE SEPARATION", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 60, no. 21, 1 November 1988 (1988-11-01), pages 2354 - 2355, XP000024604, ISSN: 0003-2700 *
See also references of WO0116582A1 *

Also Published As

Publication number Publication date
WO2001016582A1 (fr) 2001-03-08
AU7337500A (en) 2001-03-26
CA2383906A1 (fr) 2001-03-08
JP2003508748A (ja) 2003-03-04
EP1210583A1 (fr) 2002-06-05
WO2001016582A9 (fr) 2002-09-12

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20020304

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: DELPHIAN TECHNOLOGY INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20040624

RIC1 Information provided on ipc code assigned before grant

Ipc: 7G 01J 3/433 B

Ipc: 7G 01N 13/00 B

Ipc: 7G 01N 33/15 B

Ipc: 7G 01N 21/63 A

17Q First examination report despatched

Effective date: 20080602

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20081213