EP1200054A1 - Aerosol lichtschutzformulierung - Google Patents

Aerosol lichtschutzformulierung

Info

Publication number
EP1200054A1
EP1200054A1 EP00947462A EP00947462A EP1200054A1 EP 1200054 A1 EP1200054 A1 EP 1200054A1 EP 00947462 A EP00947462 A EP 00947462A EP 00947462 A EP00947462 A EP 00947462A EP 1200054 A1 EP1200054 A1 EP 1200054A1
Authority
EP
European Patent Office
Prior art keywords
composition
mixtures
group
present
stabilizer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00947462A
Other languages
English (en)
French (fr)
Inventor
Thomas Russo
Joseph Hourihan
James Sanogueira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Playtex Products LLC
Original Assignee
Playtex Products LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Playtex Products LLC filed Critical Playtex Products LLC
Publication of EP1200054A1 publication Critical patent/EP1200054A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/046Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

  • the present invention relates to sunscreens. More particularly, the present invention relates to sunscreen compositions dispensed in the form of an aerosol product that foams.
  • Sunscreen compositions are applied to the skin to protect the skin from the sun's ultraviolet rays that can lead to erythema, a reddening of the skin also known as sunburn.
  • Sunlight or ultraviolet radiation in the UV-B range has a wavelength of 290nm to 320nm and is known to be the primary cause of sunburn.
  • Ultraviolet rays at a wavelength of 320nm to 400nm, known as UV-A radiation produces tanning of the skin. However, in the process of doing so, the UV-A rays can damage or harm the skin.
  • Another long-term effect is premature aging of the skin. This condition is characterized by skin that is wrinkled, cracked and has lost its elasticity.
  • sunscreens are typically formulated with the goal of inhibiting skin damage from the sun's rays.
  • the sunscreen composition filters or blocks the harmful UV-A and UV-B rays that can damage and harm the skin. It is believed that sunscreen agents accomplish this by absorbing the UV-A and/or UV-B rays.
  • sunscreen compositions are oil and water emulsions.
  • the UV-absorbing compounds are typically incorporated into the oil phase.
  • Sunscreens may also include physical or inorganic metal oxides that block the sun's rays. Titanium dioxide and zinc oxide are commonly used for this purpose.
  • SPF sun protection factor
  • a third consideration is product feel and how well the product spreads over the skin. Typically, consumers want a product that feels smooth and silky and be applied in a smooth continuous film over the skin. Another factor is the shelf life of the product, which is determined by the chemical and physical stability of the sunscreen composition.
  • product form will also play a part since there is a variety of choices such as lotions, gels, creams, sprays, and aerosols that are available. Form preference could ultimately determine whether the consumer decides to purchase the product.
  • the unique product forms can be appealing to many consumers who are looking for something different.
  • Sunscreens that are made in the form of an aerosol are not commonplace, particularly, aerosols that deliver the product as a foam.
  • the present invention in brief summary, is a sunscreen composition that is dispensed as an aerosol product.
  • the composition contains a sunscreen agent, an emulsifier, a foam builder/stabilizer, a counterion, and a propellant.
  • the sunscreen composition also contains an emollient, a humectant, a preservative/antioxidant, and water.
  • the ratio of the foam builder/stabilizer to counterion must be about 1 :4 to about 5:1.2. More preferably, the ratio is about 1 :1 to about 5:1.
  • the present invention is a sunscreen composition in the form of an aerosol comprising a sunscreen agent, an emulsifier, a foam builder/stabilizer, a counterion, and a propellant.
  • sunscreen agents that can be used in the present invention must be capable of absorbing or blocking the harmful effects of ultraviolet radiation. In addition, they must be non-toxic and non-irritating when applied to the skin. Suitable sunscreen agents include, for example, para- aminobenzoic acid (PABA), benzophenone-1 , benzophenone-2, benzophenone-3, benzophenone-4, benzophenone-6, benzophenone-8, benzophenone-12, methoxycinnamate, ethyl dihydroxypropyl-PABA, glyceryl PABA, homosalate, methyl anthranilate, octocrylene, octyl dimethyl PABA, octyl methoxycinnamate, octyl salicylate, PABA, 2- phenylbenzimidazole-5-sulphonic acid, triethanolamine salicylate, 3-(4- methylbenzylidene)-camphor, red petrolatum, and mixtures thereof.
  • PABA para-
  • the sunscreen agents may be present in an amount about 1 wt.% to about 40 wt.% of the total weight of the composition of the present invention.
  • the total amount of sunscreen agents in the composition will depend upon the sun protection factor (SPF) desired. Normally, the higher the SPF, the greater the total amount of sunscreen agents.
  • the sunscreen agents are included at about 4 wt.% to about 30 wt.%.
  • An emulsifier is an essential component of the present invention.
  • An emulsifier enables two or more immiscible liquids to be combined homogeneously, while increasing the viscosity of the composition.
  • Emulsifiers that may be used in the present invention include sorbitan oleate, sorbitan sesquioleate, sorbitan isostearate, sorbitan trioleate, polyglyceryl-3- diisostearate, polyglycerol esters of oleic/isostearic acid, polyglyceryl-6 hexaricinolate, polyglyceryl-4-oleate, polygylceryl-4 oleate/PEG-8 propylene glycol cocoate, oleamide DEA, sodium glyceryl oleate phosphate, hydrogenated vegetable glycerides phosphate and mixtures thereof.
  • one or more synthetic polymers may be used as an emulsifier.
  • PVP Eicosene copolymer acrylat.es/C-io-C30 alkyl acrylate crosspolymer, acrylates/steareth-20 methacrylate copolymer, PEG-22/dodecyl glycol copolymer, PEG-45/dodecyl glycol copolymer, and mixtures thereof.
  • the preferred emulsifiers are PVP Eicosene copolymer, acrylates/C 10 -C 3 o alkyl acrylate crosspolymer, PEG-20 sorbitan isostearate, sorbitan isostearate, and mixtures thereof.
  • the one or more emulsifiers are present in a total amount about 0.01 wt.% to about 15 wt.% of the total weight of the composition of the present invention.
  • about 0.1 wt.% to about 3 wt.% of emulsifiers are used.
  • the composition of the present invention must include a foam builder/stabilizer.
  • the preferred foam builder/stabilizer is cetyl phosphate, DEA cetyl phosphate, TEA myristate, TEA stearate, magnesium stearate, sodium stearate, potassium laurate, potassium ricinoleate, sodium cocoate, sodium tallowate, potassium castorate, sodium oleate, and mixtures thereof.
  • the foam builder/stabilizer in an amount about 0.1 wt.% to about 5 wt.% must be added to the composition of the present invention.
  • the foam builder/stabilizer is present in an amount about 0.1 wt.% to about 3 wt.%.
  • Counterions are in the composition of the present invention to neutralize components such as an emulsifier and a foam builders/stabilizer.
  • Sodium hydroxide, potassium hydroxide, diethanolamine, triethanolamine, aminomethyl propanol, trisodium ethylenediaminetetraacetic acid, and mixtures thereof, are examples of suitable counterions used in the present invention.
  • the preferred counterion is triethanolamine.
  • Counterion is present in an amount about 0.01 wt.% to about 8 wt.% in the composition of the present invention. Preferably, counterion is present in an amount about 1 wt.% to about 5 wt.%.
  • a critical feature of the present invention is the ratio of the foam builder/stabilizer to counterion. To ensure superior foam quality and integrity, the ratio must be about 1 :4 to about 5:1.2. Preferably, the ratio is about 1 :1 to about 5:1.
  • Propellant The propellant must be capable of producing a sufficient pressure for expelling the composition from an aerosol container. Furthermore, the propellant must be non-irritating, non-toxic and compatible with the ingredients used in the composition. Suitable propellants are butane, isobutane, propane, dimethyl ether, dichlorodifluoromethane, tetrafluoromethane, dichlorotetrafluoroethane, chlorodifluoromethane, chlorodifluoroethane, difluoroethane, and mixtures thereof.
  • the preferred propellant of the present invention is a blend of isobutane and propane, commonly known as A-46 propellant.
  • Propellant is present in the range about 3 wt.% to about 15 wt.% of the present invention. Preferably, the propellant is about 5 wt.% to about 9 wt.%.
  • composition of the present invention optionally can have water.
  • Water can be present in an amount up to about 80 wt.%, preferably, from 30 wt.% to 70 wt.% of water.
  • the present composition may additionally contain one or more emollients.
  • An emollient provides a softening or soothing effect on the skin surface and is generally considered safe for topical use. Emollients also help control the rate of evaporation and the tackiness of the composition.
  • Preferred emollients include mineral oil, lanolin oil, coconut oil, cocoa butter, olive oil, aloe extracts, jojoba oils, castor oil, fatty acids such as oleic and stearic, fatty alcohols such as cetyl and hexadecyl (ENJAY), diisopropyl adipate, hydroxybenzoate esters, benzoic acid esters of C 9 -C-1 5 alcohols, isononyl iso-nonanoate, alkanes such as mineral oil, silicones such as dimethyl polysiloxane, ethers such as polyoxypropylene butyl ethers and polyoxypropylene cetyl ethers, and C ⁇ 2 -C 15 alkyl benzoates, and mixtures thereof.
  • the most preferred emollients are hydroxybenzoate esters, aloe vera, C ⁇ 2 -C 15 alkyl benzoates, and mixtures thereof.
  • Emollient is present in an amount about 1 wt.% to about 20 wt.% of the total weight of the composition.
  • the preferred amount of emollient is about 2 wt.% to about 15 wt.%, and most preferrably about 4 wt.% to about 10 wt.%.
  • Humectants A moistening agent, such as a humectant, may be incorporated into the present invention. Suitable humectants include glycerin, polyethylene glycol, polypropylene glycol, sorbitol, PEG-4, and mixtures thereof.
  • One or more humectants are optionally present at about 0.5 wt.% to about 8 wt.% in the present invention. Preferably, about 1 wt.% to about 5 wt.% of humectants may be used.
  • titanium dioxide may be added to the composition of the present invention.
  • This material is generally considered safe for topical use since it is physiologically inert and has a low degree of irritation and toxicity. It functions by reflecting and absorbing sunlight.
  • the titanium dioxide is suspended throughout the composition.
  • composition of the present invention may have about 0.5 wt.% to about 10 wt.% of titanium dioxide. Preferably, there is present about 1 wt.% to about 3 wt.% titanium dioxide.
  • preservatives/antioxidants may be in the present composition.
  • Diazolidinyl urea, iodopropynyl butylcarbamate, vitamin E, vitamin E acetate, vitamin C, butylated hydroxytoluene, methylparaben, and mixtures thereof may be a preservative/antioxidant in the present composition.
  • One or more preservatives/antioxidants may be present in an amount about 0.01 wt.% to about 2 wt.% of the total weight of the present invention. Preferably, one or more preservatives/antioxidants are present in an amount about 0.1 wt.% to about 1 wt.%.
  • the present invention may include a rheological additive, such as magnesium aluminum silicate, hydroxypropyl cellulose, carbomer, cellulose, guar gum, xanthan gum, bentonite, acrylate copolymers, and mixtures thereof.
  • a rheological additive such as magnesium aluminum silicate, hydroxypropyl cellulose, carbomer, cellulose, guar gum, xanthan gum, bentonite, acrylate copolymers, and mixtures thereof.
  • the rheological additive assists in building the viscosity of the present invention.
  • the rheological additive may optionally be present at about 0.05 wt.% to about 5 wt.% in the composition of the present invention.
  • rheological additives Preferably, about 0.1 wt.% to about 2 wt.% of rheological additives are present in the present composition.
  • the sunscreen composition of the present invention may also contain optional additives.
  • optional additives for instance, a fragrance, colorant, plant extract, absorbent, waterproofing agent, and mixtures thereof may be included.
  • the process used to manufacture the present invention must be capable of forming a homogeneous composition that can be sprayed or dispensed from an aerosol can.
  • aerosol products are made by filling a concentrate into a can and then filling the can with propellant under vacuum conditions.
  • the concentrate of the present invention may be prepared by using techniques and methods well known in the art. In general, ingredients are incorporated by mixing and applying heat if necessary, until the concentrate is uniform and homogeneous. If necessary, the concentrate may be homogenized to ensure homogeneity. The concentrate is then placed in an aerosol can which is later filled with propellant.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)
EP00947462A 1999-07-15 2000-07-14 Aerosol lichtschutzformulierung Withdrawn EP1200054A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14426499P 1999-07-15 1999-07-15
US144264P 1999-07-15
PCT/US2000/019459 WO2001005366A1 (en) 1999-07-15 2000-07-14 Sunscreen aerosol composition

Publications (1)

Publication Number Publication Date
EP1200054A1 true EP1200054A1 (de) 2002-05-02

Family

ID=22507819

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00947462A Withdrawn EP1200054A1 (de) 1999-07-15 2000-07-14 Aerosol lichtschutzformulierung

Country Status (5)

Country Link
EP (1) EP1200054A1 (de)
AU (1) AU6106500A (de)
CA (1) CA2313955A1 (de)
MX (1) MXPA02000457A (de)
WO (1) WO2001005366A1 (de)

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US6551857B2 (en) 1997-04-04 2003-04-22 Elm Technology Corporation Three dimensional structure integrated circuits
EP1411887B1 (de) * 2001-07-31 2009-04-22 MERCK PATENT GmbH Sonnenschutzzusammensetzung
KR20030013945A (ko) * 2001-08-10 2003-02-15 이인혜 분사형 선스크린제의 제조방법
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
EP1594454B8 (de) 2003-02-12 2016-10-12 Stiefel Research Australia Pty Ltd Film-bildender hydroalkoholischer schaum
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
WO2006099687A1 (en) * 2005-03-24 2006-09-28 Ensign Laboratories Pty Ltd Sunscreen aerosol spray
DE102005028388A1 (de) * 2005-06-20 2007-01-04 Wella Ag Produktabgabesystem zum Versprühen von UV-Filtern enthaltenden haar- oder hautkosmetischen Zusammensetzungen
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
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WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
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US8173108B2 (en) 2009-11-04 2012-05-08 Conopco, Inc. Sunscreen composition
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MX2017011630A (es) 2016-09-08 2018-09-25 Foamix Pharmaceuticals Ltd Composiciones y metodos para tratar rosacea y acne.

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Also Published As

Publication number Publication date
CA2313955A1 (en) 2001-01-15
MXPA02000457A (es) 2002-07-30
AU6106500A (en) 2001-02-05
WO2001005366A1 (en) 2001-01-25

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