EP1189625A1 - Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c) - Google Patents

Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c)

Info

Publication number
EP1189625A1
EP1189625A1 EP00938727A EP00938727A EP1189625A1 EP 1189625 A1 EP1189625 A1 EP 1189625A1 EP 00938727 A EP00938727 A EP 00938727A EP 00938727 A EP00938727 A EP 00938727A EP 1189625 A1 EP1189625 A1 EP 1189625A1
Authority
EP
European Patent Office
Prior art keywords
surfactant
seq
pharmaceutical preparation
surfactant protein
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00938727A
Other languages
English (en)
French (fr)
Inventor
Ernst Sturm
Ulrich Kilian
Dietrich Häfner
Paul-Georg Germann
Klaus Eistetter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Priority to EP00938727A priority Critical patent/EP1189625A1/de
Publication of EP1189625A1 publication Critical patent/EP1189625A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
EP00938727A 1999-06-11 2000-06-02 Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c) Withdrawn EP1189625A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP00938727A EP1189625A1 (de) 1999-06-11 2000-06-02 Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP99111385 1999-06-11
EP99111385 1999-06-11
PCT/EP2000/005032 WO2000076535A1 (en) 1999-06-11 2000-06-02 Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
EP00938727A EP1189625A1 (de) 1999-06-11 2000-06-02 Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c)

Publications (1)

Publication Number Publication Date
EP1189625A1 true EP1189625A1 (de) 2002-03-27

Family

ID=8238344

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00938727A Withdrawn EP1189625A1 (de) 1999-06-11 2000-06-02 Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c)

Country Status (5)

Country Link
EP (1) EP1189625A1 (de)
JP (1) JP2003501481A (de)
AU (1) AU5400000A (de)
CA (1) CA2372558A1 (de)
WO (1) WO2000076535A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003522138A (ja) * 2000-02-11 2003-07-22 アルタナ ファルマ アクチエンゲゼルシャフト 慢性肺疾患の予防および治療のための肺表面活性剤の新規使用
JP2005500349A (ja) * 2001-08-01 2005-01-06 アルタナ　ファルマ　アクチエンゲゼルシャフト 呼吸症候群のための選択的ｃｏｘ−２インヒビターと肺表面活性物質の組合せ物
AU2003302740A1 (en) * 2002-12-09 2004-07-14 Children's Hospital Medical Center Methods of diagnosis and treatment of interstitial lung disease
US8124588B2 (en) 2003-12-18 2012-02-28 Justus Liebig Universität Giessen Chimeric plasminogen activators and their pharmaceutical use
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
EP1997502A1 (de) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Rekonstituierte Tenside mit verbesserten Eigenschaften
US8399406B2 (en) 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
KR102395835B1 (ko) 2016-08-24 2022-05-10 키에시 파르마슈티시 엣스. 피. 에이. 재구성된 폐 계면활성제 조성물을 포함하는 안정한 약제학적 제제

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質
US6013619A (en) * 1988-01-06 2000-01-11 The Scripps Research Institute Pulmonary surfactants and therapeutic uses, including pulmonary lavage
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
DE4434629C1 (de) * 1994-09-28 1996-06-27 Byk Gulden Lomberg Chem Fab Zusammensetzungen zur Behandlung von IRDS und ARDS
US6315983B1 (en) * 1996-01-24 2001-11-13 Byk Gulden Lomberg Chemische Fabrik Gmbh Process for the production of powdered pulmonary surfactant preparations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0076535A1 *

Also Published As

Publication number Publication date
WO2000076535A1 (en) 2000-12-21
AU5400000A (en) 2001-01-02
JP2003501481A (ja) 2003-01-14
CA2372558A1 (en) 2000-12-21

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