EP1186891A1 - Holder for microtiterplate - Google Patents

Holder for microtiterplate Download PDF

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Publication number
EP1186891A1
EP1186891A1 EP00119174A EP00119174A EP1186891A1 EP 1186891 A1 EP1186891 A1 EP 1186891A1 EP 00119174 A EP00119174 A EP 00119174A EP 00119174 A EP00119174 A EP 00119174A EP 1186891 A1 EP1186891 A1 EP 1186891A1
Authority
EP
European Patent Office
Prior art keywords
carrier
carrier according
joint
plate
carrier plate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP00119174A
Other languages
German (de)
French (fr)
Other versions
EP1186891B1 (en
Inventor
Alfred Geiger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecan Trading AG
Original Assignee
Tecan Trading AG
Tecan Schweiz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE50013235T priority Critical patent/DE50013235D1/en
Application filed by Tecan Trading AG, Tecan Schweiz AG filed Critical Tecan Trading AG
Priority to AT00119174T priority patent/ATE334398T1/en
Priority to EP00119174A priority patent/EP1186891B1/en
Priority to PCT/EP2001/009950 priority patent/WO2002021145A1/en
Priority to US10/362,257 priority patent/US7054001B2/en
Priority to JP2002524713A priority patent/JP2004508556A/en
Priority to AU2001285913A priority patent/AU2001285913A1/en
Publication of EP1186891A1 publication Critical patent/EP1186891A1/en
Application granted granted Critical
Publication of EP1186891B1 publication Critical patent/EP1186891B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates

Definitions

  • the invention relates to a carrier for a Microtiter plate or the like.
  • Such carriers become Recording and transporting microtiter plates, as in Workstations for the handling and processing of Liquid samples, e.g. B. used for pipetting, used.
  • Carriers for microtiter plates are known in which the Carrier plate is firmly mounted on the base. At a Microtiter plate with many and correspondingly small ones, cavities can only be lightened by assembly or Manufacturing tolerances caused skew one exact and reliable processing of the samples no longer be ensured. For example, with targeted Liquid discharge into the cavities is not excluded that some of them will be missed.
  • the invention is based on the object Specify generic carrier, which also when used of very many and very small cavities Microtiter plates, as are increasingly common today, one reliable and exact processing of the liquid samples allowed.
  • the Carrier according to the invention enables in particular the reliable automatic processing of standard microtiter plates with 48 ⁇ 32 cavities.
  • a work station has (FIG. 1) a table 1 which has a plurality of parallel carriages 2 (one in FIG. 1 is one of which shown in longitudinal section) with several each Carriers 3, each carrying a microtiter plate 4, are longitudinally displaceable. Is above the table 1 can be raised and lowered, and laterally, d. H. across to A manipulator 5 is displaceable in the longitudinal direction of the carriage 2 suspended, also, can also be raised and lowered, a Pipetting head 6. The manipulator 5 can be loaded and Unload a microtiter plate 4 from a carrier 3 lift the carriage 2, move it sideways and on one Carrier of another sled or in another place lower the table 1.
  • a carrier with a Microtiter plate by longitudinally shifting the corresponding one Slide 2 under the pipetting head 6, so can the same can be lowered to the microtiter plate and Sample liquid into the wells of the microtiter plate dispense or aspirate from the same reagents.
  • the carriage 2 has (Fig. 2, 3) a carrier profile 7, which is provided on one side with idlers 8 by means of which the carriage 2 can be moved on the table 1 is supported and on the other side with guide rollers 9 with a guide rail attached to the table 1 10 intervene.
  • the guide rail 10 and the guide rollers 9 are also anchored to table 1 Cover profile 11 protected.
  • the carrier 3 has (Fig. 2) Base, which is designed as a rectangular platen 12 and is attached to the carrier profile 7. In a middle The opening of the same is a cup-shaped, open at the top Joint socket 13 made of metal, e.g. B. aluminum with a circular central opening 14 attached.
  • the joint head 16 has a vertically continuous central bore 17, which is through a Underside molded on the same, one tubular nozzle 18, with lateral play through the Opening 14 of the socket 13 protrudes, continues.
  • the connector 18 carries one near its lower end annular stop 19, on which a as a clamping ring 20th made of an elastic material, preferably plastic such as z.
  • a clamping ring 20th made of an elastic material, preferably plastic such as z.
  • B. Polypropylene formed clamping part is supported.
  • the clamping ring 20 lies with a spherical zone-shaped part its top tired of the correspondingly shaped Outer surface of the socket socket 13. He is from one surround its outer side 21, which can be clamped by means of a locking screw 22.
  • the joint head 16 lies loosely in the joint socket 13, so that the support plate 15 over a Solid angle range, the limits of which are defined by the outside of the Stutzen 18 and the edge of the opening 14 in the Joint socket 13 are determined, is freely rotatable, the Pivotal point at the top of the carrier plate 15 lies in the center of the same.
  • the carrier plate 15 is thus in particular about a vertical axis through the Center rotatable and around any, z. B. in the longitudinal direction or transverse direction at the level of the top of the Carrier plate 15 axes can be tilted.
  • the clamping ring 20 presses against the outside of the socket 13 between the same and the joint head 16 is clamped.
  • the joint is therefore determined and the spatial orientation of the Carrier plate 15 with respect to the support plate 12 and thus also the carriage 2 fixed. That of the socket 13 and the ball joint formed 16 thus allows a Adjustment of the carrier plate 15 to exactly one another Components such as B. the manipulator 5 and especially the Pipetting head 6 coordinated position by clamping the Bride 21 can be fixed by means of the locking screw 22.
  • the carrier plate 15 has (see FIGS. 4, 5) on the top two corners arranged in opposite corners Centering stops on which along a connecting them Diagonals can be moved outwards so that they are always the same distance from the center of rotation of the Carrier plate 15 have coincident center.
  • the centering stops consist of two downwards conically narrowing centering heads 23 which are transverse to said diagonal are spaced apart.
  • the opposite movement is (see Fig. 6a) by an the underside of the carrier plate 15 attached coupling controlled, which comprises a clutch lever 24 which around one running through the center of the carrier plate 15 vertical axis is rotatably connected to the same, and two diagonally displaceable by guide pins 25 same mounted slide 26a, b, each with Driver pins 27a, b in diametrically opposite on Clutch lever 24 engage recesses.
  • a clutch lever 24 which around one running through the center of the carrier plate 15 vertical axis is rotatably connected to the same, and two diagonally displaceable by guide pins 25 same mounted slide 26a, b, each with Driver pins 27a, b in diametrically opposite on Clutch lever 24 engage recesses.
  • On the outer ends of the slides 26a, b support the Centering heads 23, which through slots 28 in the Carrier plate 15 projecting shafts 29 are attached to them.
  • the clutch lever 24 sits on a vertical shaft 30, the upper end of which is centered on the underside of the carrier plate 15 is rotatably attached and which in the further by Bore 17 (Fig. 2) in the joint head 16 and nozzle 18 out is.
  • Fig. 7a carries the shaft 30 as an actuating part Actuating lever 31 with a free first arm 32 and one second arm 33, on which one on the support plate 12th anchored coil spring 34 attacks.

Abstract

Support comprises a base and a support plate (15) which is connected to the base via a hinge so that it can tilt. Preferred Features: The tilting axis lies at the height of the support plate. The support plate is able to tilt independently and can rotate over a space angle region. The hinge is formed as a socket joint with a socket (13) and a head (16). The socket joint comprises a clamping part connected to the head and lies on the outer side of the socket.

Description

Technisches GebietTechnical field

Die Erfindung betrifft einen Träger für eine Mikrotiterplatte o. dgl.. Derartige Träger werden zur Aufnahme und zum Transport von Mikrotiterplatten, wie sie in Arbeitsstationen zur Handhabung und Bearbeitung von Flüssigkeitsproben, z. B. zum Pipettieren verwendet werden, eingesetzt.The invention relates to a carrier for a Microtiter plate or the like. Such carriers become Recording and transporting microtiter plates, as in Workstations for the handling and processing of Liquid samples, e.g. B. used for pipetting, used.

Stand der TechnikState of the art

Es sind Träger für Mikrotiterplatten bekannt, bei denen die Trägerplatte fest auf der Basis montiert ist. Bei einer Mikrotiterplatte mit vielen und entsprechend kleinen Kavitäten kann jedoch bei auch nur leichter durch Montage-oder Fertigungstoleranzen verursachter Schrägstellung eine exakte und zuverlässige Bearbeitung der Proben nicht mehr sichergestellt werden. So kann etwa bei gezielter Flüssigkeitsabgabe in die Kavitäten nicht ausgeschlossen werden, dass einzelne derselben verfehlt werden.Carriers for microtiter plates are known in which the Carrier plate is firmly mounted on the base. At a Microtiter plate with many and correspondingly small ones However, cavities can only be lightened by assembly or Manufacturing tolerances caused skew one exact and reliable processing of the samples no longer be ensured. For example, with targeted Liquid discharge into the cavities is not excluded that some of them will be missed.

Darstellung der ErfindungPresentation of the invention

Der Erfindung liegt die Aufgabe zu Grunde, einen gattungsgemässen Träger anzugeben, der auch bei Verwendung von sehr viele und sehr kleine Kavitäten aufweisenden Mikrotiterplatten, wie sie heute zunehmend üblich sind, eine zuverlässige und exakte Bearbeitung der Flüssigkeitsproben erlaubt. The invention is based on the object Specify generic carrier, which also when used of very many and very small cavities Microtiter plates, as are increasingly common today, one reliable and exact processing of the liquid samples allowed.

Dies wird durch eine Ausbildung des Trägers erreicht, die eine Einstellung der räumlichen Ausrichtung der die Mikrotiterplatte aufnehmenden Trägerplatte gestattet, so dass allfällige Abweichungen derselben von einer Sollausrichtung korrigiert werden können. Der erfindungsgemässe Träger ermöglicht insbesondere die zuverlässige automatische Bearbeitung von Norm-Mikrotiterplatten mit 48×32 Kavitäten.This is achieved by training the wearer who an adjustment of the spatial orientation of the Carrier plate receiving microtiter plate allowed, so that any deviations from the same Target alignment can be corrected. The Carrier according to the invention enables in particular the reliable automatic processing of standard microtiter plates with 48 × 32 cavities.

Kurze Beschreibung der ZeichnungenBrief description of the drawings

Im folgenden wird die Erfindung anhand von Figuren, welche lediglich ein Ausführungsbeispiel darstellen, näher erläutert. Es zeigen

Fig. 1
eine Seitenansicht einer Arbeitsstation mit erfindungsgemässen Trägern,
Fig. 2
vergrössert einen Schnitt ungefähr längs II-II in Fig. 1 durch einen erfindungsgemässen Träger mit verriegelter Mikrotiterplatte und seine Verankerung an der Arbeitsstation - im Bereich der Trägerplatte folgt der Schnitt II-II in Fig. 4,
Fig. 3
einen Schnitt längs III-III in Fig. 2 durch den erfindungsgemässen Träger bei verriegelter Mikrotiterplatte,
Fig. 4
eine Draufsicht auf den erfindungsgemässen Träger mit verriegelter Mikrotiterplatte,
Fig. 5
einen Teilschnitt längs V-V in Fig. 4 durch den erfindungsgemässen Träger mit verriegelter Mikrotiterplatte,
Fig. 6a
einen Schnitt längs VI-VI in Fig. 2 durch den erfindungsgemässen Träger bei verriegelter Mikrotiterplatte,
Fig. 6b
einen Schnitt durch den erfindungsgemässen Träger enstsprechend Fig. 6a, aber bei entriegelter Mikrotiterplatte,
Fig. 7a
eine Unteransicht des erfindungsgemässen Trägers bei verriegelter Mikrotiterplatte,
Fig. 7b
eine Unteransicht des erfindungsgemässen Trägers entsprechend Fig. 7a, aber bei entriegelter Mikrotiterplatte.
In the following, the invention is explained in more detail with reference to figures, which only represent an exemplary embodiment. Show it
Fig. 1
a side view of a work station with supports according to the invention,
Fig. 2
1 enlarges a section approximately along II-II in FIG. 1 through a carrier according to the invention with a locked microtiter plate and anchoring it at the work station - in the region of the carrier plate, section II-II follows in FIG. 4,
Fig. 3
3 shows a section along III-III in FIG. 2 through the carrier according to the invention with the microtiter plate locked,
Fig. 4
2 shows a top view of the carrier according to the invention with a locked microtiter plate,
Fig. 5
4 shows a partial section along the VV in FIG. 4 through the carrier according to the invention with a locked microtiter plate,
Fig. 6a
3 shows a section along VI-VI in FIG. 2 through the carrier according to the invention with the microtiter plate locked,
Fig. 6b
6a shows a section through the carrier according to the invention, but with the microtiter plate unlocked,
Fig. 7a
2 shows a bottom view of the carrier according to the invention with the microtiter plate locked,
Fig. 7b
a bottom view of the carrier according to the invention according to Fig. 7a, but with unlocked microtiter plate.

Wege zur Ausführung der ErfindungWays of Carrying Out the Invention

Eine Arbeitsstation weist (Fig. 1) einen Tisch 1 auf, auf welchem mehrere parallele Schlitten 2 (in Fig. 1 ist einer davon längsgeschnitten dargestellt) mit jeweils mehreren Trägern 3, die jeweils eine Mikrotiterplatte 4 tragen, längsverschieblich gelagert sind. Oberhalb des Tisches 1 ist heb- und senkbar sowie seitlich, d. h. quer zur Längsrichtung der Schlitten 2 verschiebbar ein Manipulator 5 aufgehängt, ausserdem, ebenfalls heb- und senkbar, ein Pipettierkopf 6. Der Manipulator 5 kann an einer Be- und Entladestelle eine Mikrotiterplatte 4 von einem Träger 3 auf dem Schlitten 2 abheben, seitlich verschieben und auf einem Träger eines anderen Schlittens oder an einer anderen Stelle des Tisches 1 absetzen. Wird ein Träger mit einer Mikrotiterplatte durch Längsverschiebung des entsprechenden Schlittens 2 unter den Pipettierkopf 6 geschoben, so kann derselbe zur Mikrotiterplatte abgesenkt werden und Probenflüssigkeit in die Kavitäten der Mikrotiterplatte abgeben oder auch aus denselben Reagenzien ansaugen.A work station has (FIG. 1) a table 1 which has a plurality of parallel carriages 2 (one in FIG. 1 is one of which shown in longitudinal section) with several each Carriers 3, each carrying a microtiter plate 4, are longitudinally displaceable. Is above the table 1 can be raised and lowered, and laterally, d. H. across to A manipulator 5 is displaceable in the longitudinal direction of the carriage 2 suspended, also, can also be raised and lowered, a Pipetting head 6. The manipulator 5 can be loaded and Unload a microtiter plate 4 from a carrier 3 lift the carriage 2, move it sideways and on one Carrier of another sled or in another place lower the table 1. If a carrier with a Microtiter plate by longitudinally shifting the corresponding one Slide 2 under the pipetting head 6, so can the same can be lowered to the microtiter plate and Sample liquid into the wells of the microtiter plate dispense or aspirate from the same reagents.

Der Schlitten 2 weist (Fig. 2, 3) ein Trägerprofil 7 auf, welches auf der einen Seite mit Tragrollen 8 versehen ist, mittels welcher der Schlitten 2 auf dem Tisch 1 verschiebbar abgestützt ist und auf der anderen Seite mit Führungsrollen 9, die mit einer auf dem Tisch 1 befestigten Führungsschiene 10 eingreifen. Die Führungsschiene 10 und die Führungsrollen 9 sind durch ein ebenfalls am Tisch 1 verankertes Abdeckprofil 11 geschützt. Der Träger 3 hat (Fig. 2) eine Basis, welche als rechteckige Auflageplatte 12 ausgebildet und am Trägerprofil 7 befestigt ist. In einer mittigen Oeffnung derselben ist eine nach oben offene schalenförmige Gelenkspfanne 13 aus Metall, z. B. Aluminium mit einer kreisförmigen mittigen Oeffnung 14 angebracht.The carriage 2 has (Fig. 2, 3) a carrier profile 7, which is provided on one side with idlers 8 by means of which the carriage 2 can be moved on the table 1 is supported and on the other side with guide rollers 9 with a guide rail attached to the table 1 10 intervene. The guide rail 10 and the guide rollers 9 are also anchored to table 1 Cover profile 11 protected. The carrier 3 has (Fig. 2) Base, which is designed as a rectangular platen 12 and is attached to the carrier profile 7. In a middle The opening of the same is a cup-shaped, open at the top Joint socket 13 made of metal, e.g. B. aluminum with a circular central opening 14 attached.

Eine ebenfalls ungefähr rechteckige Trägerplatte 15, die die Mikrotiterplatte 4 trägt, weist an ihrer Unterseite einen Gelenkskopf 16 aus Kunststoff, z. B. Polyoxymethylen auf, welcher satt in der Gelenkspfanne 13 liegt, derart, dass ein kugelzonenförmiger Teil seiner Aussenfläche an der entsprechend geformten Innenfläche der Gelenkspfanne 13 anliegt. Der Gelenkskopf 16 weist eine vertikal durchgehende mittige Bohrung 17 auf, welche sich durch einen an der Unterseite angeformten Fortsatz desselben, einen rohrförmigen Stutzen 18, der mit seitlichem Spiel durch die Oeffnung 14 der Gelenkspfanne 13 ragt, fortsetzt.An approximately rectangular carrier plate 15, which the Bears microtiter plate 4, has on its underside Rod end 16 made of plastic, e.g. B. polyoxymethylene, which is full in the socket 13, such that a spherical part of its outer surface on the correspondingly shaped inner surface of the socket 13 is applied. The joint head 16 has a vertically continuous central bore 17, which is through a Underside molded on the same, one tubular nozzle 18, with lateral play through the Opening 14 of the socket 13 protrudes, continues.

Der Stutzen 18 trägt nahe seinem unteren Ende einen ringförmigen Anschlag 19, auf welchem ein als Klemmring 20 aus einem elastischen Material, vorzugsweise Kunststoff wie z. B. Polypropylen ausgebildetes Klemmteil abgestützt ist. Der Klemmring 20 liegt mit einem kugelzonenförmigen Teil seiner Oberseite satt an der entsprechend geformten Aussenfläche der Gelenkspfanne 13 an. Er ist von einer an seiner Aussenseite anliegenden Bride 21 umgeben, welche mittels einer Feststellschraube 22 spannbar ist.The connector 18 carries one near its lower end annular stop 19, on which a as a clamping ring 20th made of an elastic material, preferably plastic such as z. B. Polypropylene formed clamping part is supported. The clamping ring 20 lies with a spherical zone-shaped part its top tired of the correspondingly shaped Outer surface of the socket socket 13. He is from one surround its outer side 21, which can be clamped by means of a locking screw 22.

Bei gelockerter Bride 21 liegt der Gelenkskopf 16 lose in der Gelenkspfanne 13, so dass die Trägerplatte 15 über einen Raumwinkelbereich, dessen Grenzen durch die Aussenseite des Stutzens 18 und den Rand der Oeffnung 14 in der Gelenkspfanne 13 bestimmt sind, frei drehbar ist, wobei der Drehpunkt auf der Höhe der Oberseite der Trägerplatte 15 liegt, und zwar im Mittelpunkt derselben. Die Trägerplatte 15 ist damit insbesondere um eine vertikale Achse durch den Mittelpunkt drehbar und um beliebige, z. B. in Längsrichtung oder Querrichtung auf der Höhe der Oberseite der Trägerplatte 15 verlaufende Achsen kippbar.When the clamp 21 is loosened, the joint head 16 lies loosely in the joint socket 13, so that the support plate 15 over a Solid angle range, the limits of which are defined by the outside of the Stutzen 18 and the edge of the opening 14 in the Joint socket 13 are determined, is freely rotatable, the Pivotal point at the top of the carrier plate 15 lies in the center of the same. The carrier plate 15 is thus in particular about a vertical axis through the Center rotatable and around any, z. B. in the longitudinal direction or transverse direction at the level of the top of the Carrier plate 15 axes can be tilted.

Bei gespannter Bride 21 dagegen drückt der Klemmring 20 gegen die Aussenseite der Gelenkspfanne 13, die zwischen demselben und dem Gelenkskopf 16 geklemmt wird. Das Gelenk ist mithin festgestellt und die räumliche Ausrichtung der Trägerplatte 15 bezüglich der Auflageplatte 12 und damit auch des Schlittens 2 fix. Das von der Gelenkspfanne 13 und dem Gelenkskopf 16 gebildete Kugelgelenk erlaubt also eine Einstellung der Trägerplatte 15 auf eine genau auf andere Komponenten wie z. B. den Manipulator 5 und vor allem den Pipettierkopf 6 abgestimmte Lage, die durch Spannen der Bride 21 mittels der Feststellschraube 22 fixierbar ist.When the clamp 21 is tensioned, however, the clamping ring 20 presses against the outside of the socket 13 between the same and the joint head 16 is clamped. The joint is therefore determined and the spatial orientation of the Carrier plate 15 with respect to the support plate 12 and thus also the carriage 2 fixed. That of the socket 13 and the ball joint formed 16 thus allows a Adjustment of the carrier plate 15 to exactly one another Components such as B. the manipulator 5 and especially the Pipetting head 6 coordinated position by clamping the Bride 21 can be fixed by means of the locking screw 22.

Die Trägerplatte 15 weist (s. a. Fig. 4, 5) an der Oberseite zwei in einander gegenüberliegenden Ecken angeordnete Zentrieranschläge auf, welche längs einer sie verbindenden Diagonale gegengleich nach aussen verschiebbar sind, so dass sie stets gleichen Abstand vom mit dem Drehpunkt der Trägerplatte 15 zusammenfallenden Mittelpunkt haben. Jeder der Zentrieranschläge besteht aus zwei sich nach unten konisch verengenden Zentrierköpfen 23, welche quer zur besagten Diagonale voneinander beabstandet sind.The carrier plate 15 has (see FIGS. 4, 5) on the top two corners arranged in opposite corners Centering stops on which along a connecting them Diagonals can be moved outwards so that they are always the same distance from the center of rotation of the Carrier plate 15 have coincident center. Everyone The centering stops consist of two downwards conically narrowing centering heads 23 which are transverse to said diagonal are spaced apart.

Die gegengleiche Bewegung wird (s. Fig. 6a) durch eine an der Unterseite der Trägerplatte 15 angebrachte Kupplung gesteuert, welche einen Kupplungshebel 24 umfasst, der um eine durch den Mittelpunkt der Trägerplatte 15 verlaufende senkrechte Achse drehbar mit derselben verbunden ist, sowie zwei durch Führungsstifte 25 diagonal verschiebbar an derselben gelagerte Schieber 26a,b, die jeweils mit Mitnehmerstiften 27a,b in diametral gegenüberliegend am Kupplungshebel 24 angebrachte Ausnehmungen eingreifen. An ihren äusseren Enden tragen die Schieber 26a,b die Zentrierköpfe 23, die über durch Schlitze 28 in der Trägerplatte 15 ragende Schäfte 29 an ihnen befestigt sind.The opposite movement is (see Fig. 6a) by an the underside of the carrier plate 15 attached coupling controlled, which comprises a clutch lever 24 which around one running through the center of the carrier plate 15 vertical axis is rotatably connected to the same, and two diagonally displaceable by guide pins 25 same mounted slide 26a, b, each with Driver pins 27a, b in diametrically opposite on Clutch lever 24 engage recesses. On the outer ends of the slides 26a, b support the Centering heads 23, which through slots 28 in the Carrier plate 15 projecting shafts 29 are attached to them.

Der Kupplungshebel 24 sitzt an einer senkrechten Welle 30, deren oberes Ende mittig an der Unterseite der Trägerplatte 15 drehbar befestigt ist und welche im weiteren durch die Bohrung 17 (Fig. 2) im Gelenkskopf 16 und Stutzen 18 geführt ist. Unmittelbar anschliessend an das Ende des Stutzens 18 (s. Fig. 7a) trägt die Welle 30 als Betätigungsteil einen Betätigungshebel 31 mit einem freien ersten Arm 32 und einem zweiten Arm 33, an welchem eine an der Auflageplatte 12 verankerte Spiralfeder 34 angreift. Diese übt einen Zug auf den Betätigungshebel 31 aus, der ihn und damit über die Welle 30 auch den Kupplungshebel 24 und die Schieber 26a,b in der Verriegelungsstellung (Fig. 6a, 7a) hält, in der die Zentrieranschläge gegen den Rand der Mikrotiterplatte 4 drücken, wobei zwischen den Stellen, die von den beiden Zentrierköpfen 23 eines Zentrieranschlags berührt werden, jeweils eine Ecke der Mikrotiterplatte 4 liegt. The clutch lever 24 sits on a vertical shaft 30, the upper end of which is centered on the underside of the carrier plate 15 is rotatably attached and which in the further by Bore 17 (Fig. 2) in the joint head 16 and nozzle 18 out is. Immediately following the end of the nozzle 18 (see Fig. 7a) carries the shaft 30 as an actuating part Actuating lever 31 with a free first arm 32 and one second arm 33, on which one on the support plate 12th anchored coil spring 34 attacks. This trains a train the actuating lever 31 from him and thus over the Shaft 30 also the clutch lever 24 and the slider 26a, b holds in the locking position (Fig. 6a, 7a), in which the Centering stops against the edge of the microtiter plate 4 press, being between the positions of the two Centering heads 23 of a centering stop are touched, one corner of the microtiter plate 4 is located.

Wird der Betätigungshebel 31 nun z. B. mittels einer vorschieb- und zurückziehbar am Tisch 1 gelagerten, auf seinen ersten Arm 32 wirkenden Betätigungsrolle 35 oder eines anderen Betätigungselements oder auch -anschlags entgegen der Rückstellkraft der Spiralfeder 34 (in Fig. 7a im Gegenuhrzeigersinn) gedreht, so werden durch gleichsinnige Drehung des Kupplungshebels 24 die Schieber 26a,b nach aussen in eine Entriegelungsstellung (Fig. 6b, 7b) verschoben, in der die Zentrieranschläge mindestens annähernd ihre äussere Grenzstellung annehmen, in der sie vom Rand der Mikrotiterplatte frei sind. Sie sind daher nicht im Weg, wenn nun die Mikrotiterplatte z. B. mittels des Manipulators 5 von der Trägerplatte 15 abgehoben und eine andere Mikrotiterplatte auf derselben abgestellt wird.If the operating lever 31 is now z. B. by means of a advanced and retractable on table 1, on his first arm 32 acting actuating roller 35 or of another actuator or stop against the restoring force of the spiral spring 34 (in Fig. 7a counter-clockwise) are rotated by rotation of the clutch lever 24 in the same direction 26a, b outwards into an unlocking position (FIG. 6b, 7b) in which the centering stops at least approximately assume their outer limit position in which they are free from the edge of the microtiter plate. You are therefore not in the way if the microtiter plate z. B. means of the manipulator 5 lifted from the carrier plate 15 and another microtiter plate is placed on the same.

Sobald die Einwirkung auf den Betätigungshebel 31 aufhört, wird er durch die Rückstellkraft der Spiralfeder 34 in seine Grundstellung zurückgezogen, was eine entsprechende Drehung des Kupplungshebels 24 und ein Zurückschieben der Zentrieranschläge gegen den Mittelpunkt der Trägerplatte 15 hin bewirkt, wobei die auf derselben abgestellte Mikrotiterplatte durch dieselben soweit erforderlich verschoben und gedreht wird, bis die Zentrieranschläge beidseits an die Ränder derselben anstossen und sie vollständig zentriert ist.As soon as the action on the actuating lever 31 ceases, he is in his by the restoring force of the coil spring 34 Home position withdrawn, which is a corresponding rotation of the clutch lever 24 and a push back Centering stops against the center of the support plate 15 out, the one parked on the same Microtiter plate through same if necessary is moved and rotated until the centering stops knock on both sides of the edges of them and them is completely centered.

BezugszeichenlisteLIST OF REFERENCE NUMBERS

11
Tischtable
22
Schlittencarriage
33
Trägercarrier
44
Mikrotiterplattemicrotiter plate
55
Manipulatormanipulator
66
Pipettierkopf pipetting
77
Trägerprofilcarrier profile
88th
Tragrollesupporting role
99
Führungsrolleleadership
1010
Führungsschieneguide rail
1111
AbdeckprofilCover
1212
Auflageplatteplaten
1313
Gelenkspfannesocket
1414
OeffnungOpening
1515
Trägerplattesupport plate
1616
Gelenkskopfjoint head
1717
Bohrungdrilling
1818
StutzenSupport
1919
Anschlagattack
2020
Klemmringclamping ring
2121
BrideBride
2222
Feststellschraubelocking screw
2323
Zentrierkopfcentering
2424
Kupplungshebelclutch lever
2525
Führungsstiftguide pin
26a,b26a, b
Schieberpusher
27a,b27a, b
Mitnehmerstiftedriving pins
2828
Schlitzslot
2929
Schaftshaft
3030
Wellewave
3131
Betätigungshebelactuating lever
3232
erster Armfirst arm
3333
zweiter Armsecond arm
3434
Spiralfederspiral spring
3535
Betätigungsrolleactuating roll

Claims (17)

Träger für eine Mikrotiterplatte (4) o. dgl., mit einer Basis und einer Trägerplatte (15), dadurch gekennzeichnet, dass die Trägerplatte (15) mit der Basis über ein feststellbares Gelenk beschränkt kippbar verbunden ist.Carrier for a microtiter plate (4) or the like, with a base and a carrier plate (15), characterized in that the carrier plate (15) is connected to the base in a limited tiltable manner via a lockable joint. Träger nach Anspruch 1, dadurch gekennzeichnet, dass die Kippachse jeweils etwa auf der Höhe der Trägerplatte (15) liegt.Carrier according to claim 1, characterized in that the tilt axis lies approximately at the height of the carrier plate (15). Träger nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die Trägerplatte (15) nach zwei verschiedenen Richtungen unabhängig kippbar ist.Carrier according to claim 1 or 2, characterized in that the carrier plate (15) can be tilted independently in two different directions. Träger nach Anspruch 3, dadurch gekennzeichnet, dass die Trägerplatte (15) über einen Raumwinkelbereich drehbar ist.Carrier according to claim 3, characterized in that the carrier plate (15) is rotatable over a solid angle range. Träger nach Anspruch 4, dadurch gekennzeichnet, dass das Gelenk als Kugelgelenk ausgebildet ist mit einer Gelenkspfanne (13) und einem in derselben gelagerten Gelenkskopf (16).Carrier according to claim 4, characterized in that the joint is designed as a ball joint with a joint socket (13) and a joint head (16) mounted in the same. Träger nach Anspruch 5, dadurch gekennzeichnet, dass das Kugelgelenk ein mit dem Gelenkskopf (16) verbundenes Klemmteil umfasst, welches an der Aussenseite der Gelenkspfanne (13) anliegt und zur Feststellung des Gelenks an dieselbe andrückbar ist.Carrier according to claim 5, characterized in that the ball joint comprises a clamping part which is connected to the joint head (16) and which rests on the outside of the joint socket (13) and can be pressed onto the joint socket in order to fix the joint. Träger nach Anspruch 6, dadurch gekennzeichnet, dass das Klemmteil als Klemmring (20) ausgebildet ist, welcher von einer zum Andrücken desselben an die Gelenkspfanne (13) spannbaren Bride (21) umgeben ist.Carrier according to claim 6, characterized in that the clamping part is designed as a clamping ring (20) which is surrounded by a clip (21) which can be tensioned against the joint socket (13). Träger nach Anspruch 6 oder 7, dadurch gekennzeichnet, dass der Gelenkskopf (16) mit der Trägerplatte (15) verbunden ist und einen durch eine Oeffnung (14) in der Gelenkspfanne (13), welche an der Basis verankert ist, geführten Fortsatz aufweist, welcher den Klemmring (20) trägt.Carrier according to Claim 6 or 7, characterized in that the joint head (16) is connected to the carrier plate (15) and has an extension which is guided through an opening (14) in the joint socket (13) which is anchored to the base, which carries the clamping ring (20). Träger nach Anspruch 8, dadurch gekennzeichnet, dass der Fortsatz einen Anschlag (19) trägt, auf welchem der Klemmring (20) sitzt.Carrier according to claim 8, characterized in that the extension carries a stop (19) on which the clamping ring (20) sits. Träger nach einem der Ansprüche 1 bis 9, dadurch gekennzeichnet, dass die Trägerplatte (15) zwei einander auf ihrer Oberseite mit Abstand gegenüberliegende Zentrieranschläge aufweist, welche derart an der Trägerplatte (15) gelagert sind und miteinander in Wirkverbindung stehen, dass sie gegengleich von einem mittig zwischen ihnen liegenden Zentrum weg längs der Trägerplatte (15) verschiebbar sind.Carrier according to one of claims 1 to 9, characterized in that the carrier plate (15) has two centering stops which are spaced apart on their upper side and which are mounted on the carrier plate (15) in such a way and are operatively connected to one another that they are opposed by one in the center between them along the support plate (15) are displaceable. Träger nach Anspruch 10, dadurch gekennzeichnet, dass die Wirkverbindung zwischen den Zentrieranschlägen durch eine unter der Trägerplatte (15) angeordnete Kupplung hergestellt ist, welche einen drehbar an derselben angebrachten Kupplungshebel (24) umfasst sowie zwei längsverschiebbar an derselben geführte Schieber (26a, 26b), welche jeweils einen der Zentrieranschläge tragen und an einander diametral gegenüberliegenden Punkten des Kupplungshebels (24) mit demselben eingreifen. Carrier according to claim 10, characterized in that the operative connection between the centering stops is established by a coupling arranged under the carrier plate (15), which comprises a coupling lever (24) rotatably attached to the same and two slides (26a, 26b) guided longitudinally displaceably on the coupling lever. which each carry one of the centering stops and engage the clutch lever (24) at diametrically opposite points thereof. Träger nach Anspruch 10 oder 11, dadurch gekennzeichnet, dass jeder Zentrieranschlag ein Paar von Zentrierköpfen (23) umfasst, die quer zur Verschiebungsrichtung voneinander beabstandet sind.Carrier according to claim 10 or 11, characterized in that each centering stop comprises a pair of centering heads (23) which are spaced apart from one another transversely to the direction of displacement. Träger nach einem der Ansprüche 10 bis 12, dadurch gekennzeichnet, dass die Zentrieranschläge durch Einwirkung auf ein an der Unterseite des Trägers (3) angeordnetes Betätigungsteil verschiebbar sind.Carrier according to one of Claims 10 to 12, characterized in that the centering stops can be displaced by acting on an actuating part arranged on the underside of the carrier (3). Träger nach einem der Ansprüche 5 bis 9 und Anspruch 13, dadurch gekennzeichnet, dass das Betätigungsteil über eine Welle (30), welche durch das Kugelgelenk geführt ist, mit dem Kupplungshebel (24) verbunden ist.Carrier according to one of claims 5 to 9 and claim 13, characterized in that the actuating part is connected to the coupling lever (24) via a shaft (30) which is guided through the ball joint. Träger nach Anspruch 14, dadurch gekennzeichnet, dass das Betätigungsteil als an der Welle (30) befestigter Betätigungshebel (31) ausgebildet ist.Carrier according to claim 14, characterized in that the actuating part is designed as an actuating lever (31) attached to the shaft (30). Träger nach einem der Ansprüche 10 bis 15, dadurch gekennzeichnet, dass der Verschiebung der Zentrieranschläge vom Zentrum weg eine elastische Rückstellkraft entgegenwirkt.Carrier according to one of claims 10 to 15, characterized in that the displacement of the centering stops counteracts an elastic restoring force away from the center. Träger nach den Ansprüchen 15 und 16, dadurch gekennzeichnet, dass die Rückstellkraft durch eine Feder hergestellt ist, welche am Betätigungshebel (31) angreift.Carrier according to claims 15 and 16, characterized in that the restoring force is produced by a spring which acts on the actuating lever (31).
EP00119174A 2000-09-05 2000-09-05 Holder for microtiterplate Expired - Lifetime EP1186891B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AT00119174T ATE334398T1 (en) 2000-09-05 2000-09-05 CARRIER FOR A MICRO TITRE PLATE
EP00119174A EP1186891B1 (en) 2000-09-05 2000-09-05 Holder for microtiterplate
DE50013235T DE50013235D1 (en) 2000-09-05 2000-09-05 Carrier for a microtiter plate
US10/362,257 US7054001B2 (en) 2000-09-05 2001-08-29 Support for a microtiter plate
PCT/EP2001/009950 WO2002021145A1 (en) 2000-09-05 2001-08-29 Support for a microtiter plate
JP2002524713A JP2004508556A (en) 2000-09-05 2001-08-29 Microtiter plate support
AU2001285913A AU2001285913A1 (en) 2000-09-05 2001-08-29 Support for a microtiter plate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00119174A EP1186891B1 (en) 2000-09-05 2000-09-05 Holder for microtiterplate

Publications (2)

Publication Number Publication Date
EP1186891A1 true EP1186891A1 (en) 2002-03-13
EP1186891B1 EP1186891B1 (en) 2006-07-26

Family

ID=8169753

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00119174A Expired - Lifetime EP1186891B1 (en) 2000-09-05 2000-09-05 Holder for microtiterplate

Country Status (7)

Country Link
US (1) US7054001B2 (en)
EP (1) EP1186891B1 (en)
JP (1) JP2004508556A (en)
AT (1) ATE334398T1 (en)
AU (1) AU2001285913A1 (en)
DE (1) DE50013235D1 (en)
WO (1) WO2002021145A1 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10261533A1 (en) * 2002-12-23 2004-07-15 BioChip Technologies GmbH Gesellschaft für Entwicklung und Produktion von Detektionssystemen Holder for slide onto which droplet array is deposited, includes locating stops on long side of slide support surface, used in conjunction with clamping system
DE102004021664A1 (en) * 2004-05-03 2005-12-08 H+P Labortechnik Ag Microtitration plate shaker for e.g. pharmaceutical, chemical or biological research, has locators driven between working- and release positions
WO2009121363A1 (en) * 2008-04-02 2009-10-08 Danmarks Tekniske Universitet Dtu Adjustable chip holder
WO2010106147A1 (en) 2009-03-18 2010-09-23 Quantifoil Instruments Gmbh Positioning device for a sample carrier
WO2011113858A1 (en) 2010-03-18 2011-09-22 Quantifoil Instruments Gmbh Positioning unit for a functional unit
DE102020133424A1 (en) 2020-12-14 2022-06-15 Qinstruments Gmbh LAB UNIT WITH MIXING MECHANISM FOR MIXING MEDIUM ON SLIDE
DE102020133420A1 (en) 2020-12-14 2022-06-15 Qinstruments Gmbh LAB UNIT WITH FIXING MECHANISM FOR FIXING A SLIDE

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7516934B2 (en) * 2006-02-24 2009-04-14 Bio-Rad Laboratories, Inc. Sample plate support of adjustable angular orientation
US8296088B2 (en) * 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
JP2013205383A (en) * 2012-03-29 2013-10-07 Tsubakimoto Chain Co Tube storage system for drug discovery
JP5939720B1 (en) * 2015-03-31 2016-06-22 株式会社椿本チエイン Rack positioning device

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826558A (en) * 1972-07-21 1974-07-30 Us Air Force Mechanical rotary tilt stage
EP0301583A2 (en) * 1987-07-31 1989-02-01 Fujirebio Kabushiki Kaisha Automatic immunological analysing apparatus
EP0396115A2 (en) * 1989-05-03 1990-11-07 Abbott Laboratories Method of forming agglutinates in blood samples
EP0625708A2 (en) * 1993-05-17 1994-11-23 Fujirebio Inc. Method and apparatus for indirect agglutination immunoassay
US5592289A (en) * 1995-01-09 1997-01-07 Molecular Dynamics Self-aligning mechanism for positioning analyte receptacles
WO1999015905A1 (en) * 1997-09-24 1999-04-01 Glaxo Group Limited Systems and methods for handling and manipulating multi-well plates
US6037733A (en) * 1996-03-22 2000-03-14 Genmark Automation Robot having multiple degrees of freedom

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012111A (en) * 1975-08-25 1977-03-15 Honeywell Inc. Microscope object slide positioning system
DE3027216A1 (en) * 1980-02-21 1982-02-11 Manfred P. Dr. 7141 Schwieberdingen Zeiser Dental cast making equipment with drill - includes work table for drilling operations, with pneumatically operated clamps acting as centering members
DE3128394C2 (en) * 1981-07-17 1986-02-13 Harald A. Dipl.-Ing. 6800 Mannheim Solmitz Method and device for the adjustable mounting of printing plates in materials testing machines
JPS6126648U (en) * 1984-07-23 1986-02-17 トヨタ自動車株式会社 Indoor mirror mounting structure
WO1986007232A1 (en) * 1985-05-28 1986-12-04 American Telephone & Telegraph Company Apparatus for positioning a circuit panel
US4710031A (en) * 1985-07-31 1987-12-01 Lancraft, Inc. Microtiter plate reader
US5295700A (en) * 1992-04-16 1994-03-22 Dukane Corporation Workpiece support assembly for microrobotic apparatus
US5328019A (en) * 1992-11-25 1994-07-12 Eastman Kodak Company Autoloader for cassettes and/or pallet
DE4302950A1 (en) * 1993-02-03 1994-08-04 Mekra Rangau Plastics Adjustable rearview mirror assembly for motor vehicles
FI954512A0 (en) * 1995-09-22 1995-09-22 Labsystems Oy Plattbaerare

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826558A (en) * 1972-07-21 1974-07-30 Us Air Force Mechanical rotary tilt stage
EP0301583A2 (en) * 1987-07-31 1989-02-01 Fujirebio Kabushiki Kaisha Automatic immunological analysing apparatus
EP0396115A2 (en) * 1989-05-03 1990-11-07 Abbott Laboratories Method of forming agglutinates in blood samples
EP0625708A2 (en) * 1993-05-17 1994-11-23 Fujirebio Inc. Method and apparatus for indirect agglutination immunoassay
US5592289A (en) * 1995-01-09 1997-01-07 Molecular Dynamics Self-aligning mechanism for positioning analyte receptacles
US6037733A (en) * 1996-03-22 2000-03-14 Genmark Automation Robot having multiple degrees of freedom
WO1999015905A1 (en) * 1997-09-24 1999-04-01 Glaxo Group Limited Systems and methods for handling and manipulating multi-well plates

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10261533A1 (en) * 2002-12-23 2004-07-15 BioChip Technologies GmbH Gesellschaft für Entwicklung und Produktion von Detektionssystemen Holder for slide onto which droplet array is deposited, includes locating stops on long side of slide support surface, used in conjunction with clamping system
DE102004021664A1 (en) * 2004-05-03 2005-12-08 H+P Labortechnik Ag Microtitration plate shaker for e.g. pharmaceutical, chemical or biological research, has locators driven between working- and release positions
WO2009121363A1 (en) * 2008-04-02 2009-10-08 Danmarks Tekniske Universitet Dtu Adjustable chip holder
EP2108452A1 (en) * 2008-04-02 2009-10-14 Danmarks Tekniske Universitet (DTU) Adjustable chip holder
US9126200B2 (en) 2009-03-18 2015-09-08 Quantifoil Instruments Gmbh Positioning device for a sample carrier
WO2010106147A1 (en) 2009-03-18 2010-09-23 Quantifoil Instruments Gmbh Positioning device for a sample carrier
DE102009013778A1 (en) 2009-03-18 2010-09-23 Quantifoil Instruments Gmbh Positioning device for a sample carrier
US9132428B2 (en) 2009-03-18 2015-09-15 Quantifoil Instruments Gmbh Positioning device for a sample carrier
DE102009013778B4 (en) * 2009-03-18 2013-08-14 Quantifoil Instruments Gmbh Positioning device for a sample carrier
WO2011113858A1 (en) 2010-03-18 2011-09-22 Quantifoil Instruments Gmbh Positioning unit for a functional unit
DE102010011899B4 (en) * 2010-03-18 2013-11-21 Quantifoil Instruments Gmbh Positioning device for a functional device
US9126162B2 (en) 2010-03-18 2015-09-08 Quantifoil Instruments Gmbh Positioning unit for a functional unit
DE102010011899A1 (en) 2010-03-18 2011-09-22 Quantifoil Instruments Gmbh Positioning device for a functional device
DE102020133424A1 (en) 2020-12-14 2022-06-15 Qinstruments Gmbh LAB UNIT WITH MIXING MECHANISM FOR MIXING MEDIUM ON SLIDE
DE102020133420A1 (en) 2020-12-14 2022-06-15 Qinstruments Gmbh LAB UNIT WITH FIXING MECHANISM FOR FIXING A SLIDE

Also Published As

Publication number Publication date
AU2001285913A1 (en) 2002-03-22
US7054001B2 (en) 2006-05-30
DE50013235D1 (en) 2006-09-07
WO2002021145A1 (en) 2002-03-14
JP2004508556A (en) 2004-03-18
EP1186891B1 (en) 2006-07-26
ATE334398T1 (en) 2006-08-15
US20030174394A1 (en) 2003-09-18

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