EP1178741A2

EP1178741A2 - Smokable product

Info

Publication number: EP1178741A2
Application number: EP99911715A
Authority: EP
Inventors: Werner Rahn; Wolfram Röper; Henning Seidel
Original assignee: HF and PhF Reemtsma GmbH and Co
Current assignee: Reemtsma Cigarettenfabriken GmbH
Priority date: 1999-02-26
Filing date: 1999-02-26
Publication date: 2002-02-13
Also published as: CA2360852A1; JP2003500008A; WO2000049901A2; HUP0203227A2; KR20010108248A; BG105844A; PL353568A1; TR200102488T2; SK12032001A3; EA200100917A1; AU3030799A; TW480157B; NO20014133D0; WO2000049901A3; HRP20010596A2; EE200100445A; NO20014133L; CZ20012899A3; IS6059A; HUP0203227A3

Abstract

The invention relates to smokable products such as filter cigarettes, filter cigarillos or cigars with filters which are provided with a gaseous phase active filter and/or a gaseous phase active cigarette paper and/or one or more other components with a content in gaseous phase active substances that are accessible to the main stream of smoke and to which antioxidant substances have been added.

Description

Smokable product

The present invention relates to smokable products, such as filter cigarettes, filter cigarillos or filtered cigars, which have a gas-phase-active filter and / or gas-phase-active cigarette paper and / or one or more other components accessible to the mainstream smoke with an addition of gas-phase-active substances and with an additive are provided with antioxidant substances.

Different approaches are used to reduce the risk potential of smokable tobacco products. One of the best known is, for example, the design of so-called "light" or "ultra-light" cigarettes. These cigarettes reduce the particle as well as the gas phase of their so-called mainstream smoke and thus its overall risk potential by means of strongly retaining filters in connection with a suitably adapted filter ventilation.

Furthermore, filter systems with deposits of gas-phase-active substances such as activated carbon are known which specifically reduce the gas phase of cigarillos or cigarettes. Such filter cigarettes

CONFIRMATION COPY are described, for example, in DE-PS 41 05 500 Cl or EP-PS 0 558 166 B1.

DE-PS 44 16 101 C2 also discloses smokable tobacco products which contain natural antioxidative substances for reducing the mutagenic potential of tobacco smoke.

None of the previously known, above Proposed solutions, however, show the reduction, possibly even compensation, of the undesired influence of tobacco smoke on the impairment of the microcirculation of the bloodstream.

The distribution of blood in the smallest blood vessels - the microcirculation - is the most important part of the blood circulation. This is where the diffusion of oxygen, nutrients and metabolic products between blood and tissue cells takes place. There are major differences between the microcirculation and the macrocirculation in the arteries and veins: in the smallest blood vessels (capillaries, arterioles and venules), blood cells and blood plasma separate more or less and only reunite in the veins after they have flowed through the microvascular network. The microcirculation is adapted to the requirements of the respective tissue by a series of control mechanisms, its functional state is determined by the flow properties and flow conditions of the blood.

The distribution of blood cells in the microvessels is important both for the "nutrition" of adjacent tissue cells (red blood cells) and for the immune response (white blood cells).

When smoking, the functional state of the microcirculation in the oral mucosa - a representative organ region - and other organs or organ regions is temporarily changed. The first time the oral mucosa comes into contact with tobacco smoke - but also with other substances that are absorbed through the respiratory or nutritional tract - it is particularly powerful Organ region for perception and defense against environmental influences. While smoking a cigarette and a few minutes later, the blood distribution in the microvessels is somewhat restricted, the flow strength in the small blood vessels decreases, and white blood cells appear in the vessels, which temporarily on the Adherent vessel walls (initiation of an immune reaction).

The short-term restrictions of blood distribution and blood flow due to smoking can be compensated for by healthy people through the body's own control mechanisms and are therefore not of particular concern. Even in "normal" daily life, the microcirculation is subject in part. significantly larger fluctuations. The effects of smoking desired by the smoker also include the slight increase in blood pressure caused by the narrowing of the vessels.

The behavior of white blood cells when smoking (i.e. their accumulation and attachment to the walls of the vessel) is a normal reaction of the body's defense system, which perceives cigarette smoke as a disruptive factor. Such immune reactions guarantee the protection of the organism against influences from the outside world. A normal immune system tolerates the acute changes observed in smoking related to white blood cells. When assessing the possible consequences of smoking, the extent and possible subsequent reactions (inflammatory reactions) must be taken into account. It should be an advantage if e.g. a cigarette affects the local microcirculation and immune system as little as possible.

It is therefore an object of the present invention to provide smokable products whose main flow smoke (HSR) and secondary flow smoke (NSR) significantly impair or reduce the microcirculation - especially in the oral mucosa - than it does in conventional products with comparable nicotine and condensate values is the case with simultaneous guarantee of taste acceptance, ie without negatively influencing the taste properties of the products.

The object is achieved according to the invention by a smokable product, e.g. a filter cigarette, a filter cigarillo or a filtered cigar, solved that

a) contains a gas phase active filter and / or gas phase active cigarette paper and / or one or more others, the

Components accessible to mainstream smoke contain an addition of gas-phase-active substances and b) the strand of tobacco and / or another smokable material and / or other components accessible to the mainstream smoke is / are provided with an addition of substances having an antioxidative effect.

In the context of the present invention, “components accessible to the mainstream smoke” are understood to mean those constituents of smokable products such as cigarettes, cigarillos or cigars which form part or all of the substances which pass into the mainstream smoke when smoked, or other components which elute into the mainstream smoke when smoking become.

It has surprisingly been found in the context of the present invention that the basic idea of the invention, namely the trouble-free, i.e. not mutually interfering - combination of two opposing mechanisms a wealth of positive effects is achieved. The substantial enrichment of one relevant part of the smoke - the gas phase - of undesirable substances with simultaneous enrichment of the other relevant part of the smoke - the particle phase - with protective, natural substances result side by side

- Reduction of cytotoxicity through carbon filters (Fundamental and Applied Toxicology 39, 11-17 (1997)) Reduction of mutagenicity (DE-PS 4 16 101 C2)

Reduction of microcirculation impairment by both mainstream and bypass smoke

as well as an additional one

Improvement of mainstream smoke taste,

- improvement of the sidestream smoke smell,

to a surprisingly large extent.

On the basis of the basic idea according to the invention - depletion of the gas phase with simultaneous enrichment of the particle phase - in principle all design parameters known or familiar to the person skilled in the art (ie use of different filter types, use of different tobacco or tobacco mixtures, use of different tobacco rod wrappings, selection of the components ten, which are acted upon with antioxidant substances, etc.) for the design of the cigarettes and cigarillos according to the invention or their variants in, for example, the known value segments such as filling flavor, medium, lights and ultra-lights.

The invention thus relates to a smokable product which contains a gas-phase-active filter and / or gas-phase-active cigarette paper and whose strand of tobacco and / or another smokable material and / or other components accessible to the mainstream smoke is provided with an additive of substances having an antioxidative effect /are.

The product contains either a tobacco rod wrapped in cigarette paper or a tobacco rod wrapped in non-woven paper and cigarette paper, the air permeability of the cigarette paper being 10 to 100 Coresta units (CU), preferably 20 is up to 60 CU, and the air permeability of the nonwoven paper is 4000 to 60,000 CU. Alternatively, the product contains either a tobacco rod wrapped in natural and / or reconstituted tobacco or a tobacco rod wrapped in at least two layers of reconstituted tobacco or film tobacco, the air permeability of one layer of film tobacco being either <1 CU ("air impermeable"), or 5 to 100 CU ("air permeable"), preferably 40 to 80 CU.

In the context of the present invention, “gas-phase active filter” is understood to mean a filter which contains 5 to 65% by weight, preferably 20 to 50% by weight, particularly preferably 30% by weight, of a gas-phase-active, porous material of large (inner) Contains surface.

Preferably, the filter has a circumferential filter ventilation zone in the underside and the degree of filter ventilation is 5 to 95%, preferably 25 to 75%. However, the filter can also contain means for introducing ventilation air into the filter at a different or arbitrary location known to the person skilled in the art. For example, both filter wrapping papers and tipping can be partially or completely zone perforated or naturally porous.

According to a particular embodiment, the gas phase active filter is a double filter, but it can also e.g. be a mono- or multifilter, the multifilter being any combination of filters from the group consisting of chamber filters, litter filters, monobloc filters and / or core filters. In the case of the double filter, the strand-side part — in the case of the monofilter the whole part — preferably consists of a tissue paper which contains 5 to 65% by weight, preferably 20 to 50% by weight and particularly preferably 30% by weight, of such a surface-rich, gas phase-active material contains.

According to a special embodiment, the smokable product is either a filter cigarette with a by a tobacco rod surrounded by cigarette paper or around a filter cigarillo (without cigarette paper) or a filtered cigar, the tobacco rod being surrounded by a cover sheet or a cover and binder made from natural or reconstituted tobacco.

A preferred filter - preferably a double filter - has a circumferential filter ventilation zone in the mouth-side part, the tissue paper of the strand-side filter part being a very voluminous paper. According to this embodiment, the air permeability of the cigarette paper is 10 to 100 Coresta units (CU), preferably 20 to 60 CU, and the degree of filter ventilation is 5 to 95%, preferably 25 to 75%.

The tissue paper (in the case of the double filter the tissue paper of the strand-side filter part) preferably contains 30% by weight of a surface-rich material. The strand-side part of the filter is, in particular, a core filter with a core made of tissue paper, which is surrounded by a jacket made of material which is almost impermeable to the mainstream smoke.

According to the invention, the gas phase-active filter contains a surface-rich, gas phase-active material which is a porous material with a large (inner) surface from the group consisting of activated carbon, aluminum oxide, aluminum hydroxide, bentonite, cellulose, diatomaceous earth, ion exchangers, light metal salts, sea foam, molecular sieves, Silica gels, clays, and zeolites or combinations thereof, with activated carbon, meerschaum and silica gel being particularly preferred as gas phase-active substances.

In the filter construction, commercially available chamber filters (triple filters) can be used, in which the centrally arranged chamber to be filled with the above-mentioned surface-rich, gas-phase-active material can vary in size depending on the amount of gas phase to be sorbed. Here come in the Weight amounts of 25 mg to 250 mg of the surface-rich materials mentioned are generally used, the specific amounts used depending on the grain size, bulk density and degree of ventilation of the preferably ventilated filters varying within the weight range mentioned. It is important here that the chamber is filled as much as possible. Surprisingly, it has been shown that even with larger amounts of gas-phase-active substance, for example 100 mg of a commonly used activated carbon, the negative taste effect known to the person skilled in the art ("off taste", "off flavor") is compensated for by antioxidant extracts, such as tocopherol acetate or can be overcompensated, while producing a particularly good taste.

Furthermore, other filter constructions known per se with gas-phase-active material can be used, for example a litter filter (for example, in the case of a double filter, the line-side filter section is preferably provided with deposits, for example granular, gas-phase-active materials in quantities of 10 to 150 mg), monobloc filter ( the gas-phase-active material, preferably activated carbon, is partially bonded in the form of a cylindrical body with, for example, polyolefins), multifilters which contain at least two, possibly different, forms of offering the gas-phase-active material - which may also be different - in addition to the filter phase-retaining filter sections, as well as core Filters in which either the sheath or the core contain or consist of gas-phase-active material, alternatively core filters in which both the sheath and the core contain gas-phase-active but different material or consist of it and other filter constructions of the specified type known to the person skilled in the art. In this connection, the filters can be channel-ventilated and / or have a mouth-side recess filter section and / or a mouth-side core filter. All of the filter structures mentioned, which contain gas-phase-active material, can even have the antioxidative substances according to the invention both in contain gas-phase-active as well as in the particle-phase-retentive material and additionally be provided with further, admissible additives such as flavors, fragrances, common filter hardeners and other admissible additives for cigarettes and cigarillos. It goes without saying that the filter structures mentioned which contain gas-phase-active material are also provided with customary filter material which retains the particle phase or additional filter sections which retain the particle phase, in particular with cellulose, cellulose acetate and those described in DE-PS 197 53 193 and DE- PS 197 53 195 and filter materials which retain particle phase and are described in DE-OS 42 05 658.

In the context of the present invention, it has proven to be advantageous to use a surface-rich material with a grain size of 2 mm or less, preferably from 15 μm to 2 mm, or according to a particular embodiment less than 15 μm, which has an inner specific surface in the area

2 2 from 50 m Ig to 2000 m / g. This applies both to filter cigarettes and to the filtered cigarillos or cigars according to the invention.

In the context of the present invention, “gas-phase-active cigarette paper” is understood to mean a cigarette paper which contains at least one of the abovementioned surface-rich, gas-phase-active materials. For example, the cigarette paper can be provided with very fine-grained silica gels, zeolites, aluminum oxides, etc. Alternatively, the gas-phase-active cigarette paper can, for example, be a two-layer tobacco rod wrapper which is provided with finely ground activated carbon in a manner known per se (carbon filled paper innerliner for cigarettes and cigars; Ecusta Paper Division OLIN; Research & Development Dept. report; August 27, 1973).

A preferred embodiment of the invention according to the invention is therefore a filter cigarette, the tobacco rod of which has two layers

Cigarette paper is wrapped, with the inner layer made of one By-flow smoke-reducing cigarette paper with low air permeability and the outer layer consists of a flavored cigarette paper with an air permeability of 20 to 100 CU, preferably 40 to 80 CU.

The antioxidative substances added to the tobacco and / or other smokable materials are preferably selected from the group consisting of ascorbic acid, β-carotene, retinol, tocopherol (in particular α-tocopherol), their derivatives (in particular tocopherol acetate) and precursors, eugenol, jasmine aldehyde , Cinnamon, cinnamon extract, (raw) coffee, (raw) coffee extract, caffeic acid methyl ester, caffeic acid ethyl ester, ferulic acid methyl ester, ferulic acid ethyl ester, umbelliferone, scopoletin and curcumin, the substances being selected either individually or in combination can be added together to the tobacco. According to a particularly preferred embodiment of the invention, the additive contains or comprises α-tocopherol, tocopherol acetate (ToAc) and / or tocopherol succinate.

According to the invention, the tobacco rod is added with more than 0.1% by weight to 5% by weight (based on the amount of tobacco), preferably more than 0.5% by weight to 4% by weight and particularly preferably 1 % By weight to 2.5% by weight of antioxidant substances. If the additive comprises more than one antioxidative substance, the amount added to the tobacco is in each case at least 0.25% by weight to 1.25% by weight according to a particular embodiment of the invention.

According to the basic idea of the invention - depletion of the gas phase with simultaneous enrichment of the particle phase - not only antioxidative substances can be added to the components of the smokable products which are accessible to the mainstream smoke, but also also the surface-rich, gas-phase-active materials mentioned. Depending on the type of smokable product, this addition of gas-phase-active substances can optionally be carried out with a gas-phase-active filter and / or gas-phase-active cigarette paper can be combined or replace the gas-phase-active filter and / or the gas-phase-active cigarette paper.

The filter cigarette of the present invention has a tobacco rod surrounded by cigarette paper. Instead of tobacco, other smokable materials, including mixtures of these other materials containing tobacco, can also be used in the products according to the invention. For example, according to the invention, “Kretek” cigarettes with the addition of up to 50% by weight of smokable spices or pure, tobacco-free plant cigarettes are also included. In the following, reference is made exclusively to "tobacco", but this term is always intended to include the other smokable materials mentioned.

The tobacco or tobacco mixtures used consist either entirely or predominantly of expanded or unexpanded La ina tobacco, but can also contain so-called technical tobacco such as rib cut or foil tobacco (FT). In a preferred embodiment, the antioxidative substances according to the invention are advantageously incorporated directly into the film tobacco in a manner known to those skilled in the art. Depending on the physical nature and technically relevant peculiarities of the antioxidant substances according to the invention and the intended use, the amounts of 0.1 to 10%, preferably 1% to 7% and particularly preferably 2% to 4 of the film tobacco are used % incorporated. Such film tobacco is particularly suitable for use in cigarillos and cigars, for example as cover and / or binder, but can also be used directly as (smokable) tobacco or added to the tobacco mixtures for cigarillos, cigars or cigarettes in the form of coarse or fine cuts become. The following tobacco mixtures for cigarettes can be used:

pure Virginia blends ("light") - light blends with an oriental component known as American blend (AB) blends dark blends (air cured).

These mixtures can also contain technical tobacco (ribs, FT), where the respective lamina (leaf tobacco) portions can be wholly or partially expanded. In any case, the mixtures or the smoke products according to the invention to be produced therefrom contain the claimed antioxidative substances. AB mixtures are often used, e.g. according to the following mixture recipe range preferred according to the invention:

a) 20 to 40% air cured tobacco b) 20 to 70% Virginia tobacco c) 5 to 20% oriental tobacco d) 0 to 25% foil tobacco e) 5 to 15% rib cut f) 0.1 to 5% antioxidant natural substances,

as well as the usual additives such as "Casing" and "Flavor".

American blend (AB) mixtures are preferred, in special cases, i.e. in terms of taste

Positioning of the product can result in deviations or other tobacco blends from "light" to "dark" can be used.

For "cigarillos" or "cigars", rather "dark" tobacco mixtures based on air-cured tobacco, the antioxidative natural substances and other tobacco known to the person skilled in the art or the usual additives are used. Particularly in the case of filter cigarillos in the form of cigarettes, adds a subset, if necessary the entire amount of the natural substances having an antioxidative effect to the tobacco foil binder.

In principle, the antioxidative substances can not only be added to the tobacco, but also incorporated into individual components of the tobacco products that are accessible to the mainstream smoke, such as filters, wrapping papers, wrapping tobacco, carrier substances, seam glue, etc., in a manner known per se. If the antioxidative substances are incorporated in the cigarette paper or in the glue of the cigarette seam, the preferred amounts are more than 0.1% by weight to 20% by weight, with amounts of 1 to 7.5% by weight being particularly preferred are preferred. In addition to the above-mentioned substances with an antioxidative effect, the tobacco rod can also be provided in a manner known per se with further additions of auxiliaries, fillers and flavorings (additives).

When adding large amounts of antioxidant substances to the tobacco mixture, especially when adding tocopherol acetate, it has proven to be advantageous to provide the tobacco rod with a double-layer cigarette rod wrapper (non-woven paper), the inner layer made of highly porous wrapping paper with an air permeability of 4000 to 60 000 CU consists and the outer layer of cigarette paper, which is customary per se. This advantageously eliminates any migration effects of the liquid additive from the tobacco mixture of the cigarette to the outer cigarette paper, e.g. characterized by an undesirable staining, prevented or at least reduced. Alternatively, smaller amounts of the antioxidative substances added according to the invention according to DE-PS 42 44 467 can also be applied in encapsulated form to the inner, highly porous wrapping paper.

Other multi-layer tobacco rod wrapping combinations can also be used. For example, special ciga Rescue papers for a wide variety of purposes known to those skilled in the art can be combined or used with the internal, highly porous wrapping paper, such as flavored papers (for example according to EP 0 294 972), sidestream smoke reducing papers (for example according to EP 0 251 254 or EP 0 338) 156) or papers for self-extinguishing cigarettes (for example according to EP 0 375 844). Of course, these cigarette papers - especially when using smaller amounts of substances having an antioxidative effect on the smoking article according to the invention - can also be used on their own, ie in one layer. This possibility also exists with foil tobacco wrappings, especially with cigarillos. Combinations of preferred tobacco rod wrapping combinations according to the invention are shown in Table 1.

Tab. 1

In Tab. 1 the first (upper) block relates to the filtered cigarillos or cigars according to the invention, the second (lower) block relates to the filter cigarettes according to the invention. In principle, the wrappings listed can be meaningfully interchanged or combined with one another (within a line) or with one another (different lines).

Also included according to the invention is a filter cigarillo, e.g. an approximately cigarette-shaped filter cigarillo, which is provided with a sheet of air-permeable or air-impermeable film tobacco and a cover sheet of natural tobacco and has a chamber filter, the central chamber of which is filled with activated carbon.

According to a particularly preferred embodiment of the invention, the filter used is a gas-phase-active filter according to PCT / EP97 / 06390, which is a filter containing activated carbon, the filter cigarette produced with this filter

(a) contains a tobacco rod surrounded by a cigarette paper with an air permeability of 20 to 100 CU or a tobacco rod covered by a cigarette paper with an air permeability of 20 to 100 CU, and

b) contains a double filter with a degree of filter ventilation of 5 to 95%, the strand-side part of which consists of a very voluminous tissue paper containing 5 to 65% by weight, preferably 20 to 50% by weight, microfine ground activated carbon, in the mouth-side part is provided with a filter ventilation zone running in the circumferential direction.

According to the invention, the above-mentioned substances are preferably added to the tobacco rod either individually or in combination with one another. However, these substances can also be used in addition to other components of the invention tobacco products according to the invention are added, of which preferably the mouth-side filter part.

According to one embodiment, the tissue paper used in the strand-side filter element has a basis weight of approximately 40 to 60 g / m ² , an activated carbon content of 5 to 65% and a thickness of 150 to 200 μm. A preferred variant has a weight per unit area of 50 g / m ² and an activated carbon content of 30% by weight with a thickness of 180 μm.

In a particular embodiment, the strand-side filter part of the double filter is a core filter according to DE 42 05 658 C2, in which the core is made of carbon-containing tissue paper as in the first-mentioned embodiment, which is surrounded by a jacket made of material which is almost impermeable to the mainstream smoke . This almost smoke-impermeable material consists, for example, of highly compressed cellulose acetate fibers.

The filter cigarette according to the invention has the advantage over conventional filter cigarettes of comparable strength that the microcirculation, in particular of the oral mucosa, is significantly less impaired when a gas-phase-active filter is used and additional antioxidative substances are added to the tobacco rod, thus preventing undersupply of the tissue becomes. This positive effect is significantly enhanced especially when α-tocopherol or tocopherol acetate is added.

In the context of the present invention it was surprisingly found that - even when using a gas phase-active filter containing activated carbon, for example, which also retains the particle phase - considerable amounts of the added antioxidant substances pass into the particle phase and their amount does not pass through the gas phase or particle phase active filter or is only slightly reduced, the filter or the pores of the gas phase active filter material are not "blocked" by these tobacco additives, ie they do not clog. Surprisingly, there is an additive or superadditive effect of the individual effects of the combination of gas-phase active filter and exposure to antioxidative substances, ie there is an at least additive reduction in the impairment of the microcirculation. On the other hand, it has been shown that the proportion of pollutants in the gas phase can be reduced by using a gas phase-active filter without the taste according to the invention being adversely affected, that is to say the taste of the main stream smoke is adversely affected. The sidestream smoke likewise has no negative, ie unpleasant, odor changes.

Surprisingly, it has also been shown that an exposure to conventional tobacco mixtures with the above-mentioned. substances with an antioxidative effect - also in higher proportions - contribute to a sensory improvement of the respective mixture or of the smokable products according to the invention.

According to a particular embodiment of the invention, the smokable product is a filter cigarette which contains a tobacco rod covered with a cigarette paper with an air permeability of 40 to 60 CU, the nonwoven paper being a highly porous nonwoven paper with an air permeability of 32,000 CU, and the filter of which is a double filter is, the strand-side part of a very voluminous, 30 wt .-%, microfine ground activated carbon-containing tissue paper, which is provided with a circumferential filter ventilation zone, which consists of cellulose acetate in the mouth-side part, the tobacco rod with a Addition of about 2% tocopherol acetate is provided. Depending on whether it is a full-flavor, a lights or an ultra-lights cigarette, the double filter has a degree of filter ventilation of about 20 to about 25%, about 50% or about 60 to 75%. The product Properties of these preferred cigarettes are shown in Table 2 below.

Tab. 2

It is self-evident to the person skilled in the art that the principle according to the invention - enrichment of the gas phase, for example by using a gas-phase-active filter and / or by using gas-phase-active cigarette paper, with simultaneous enrichment of the particle phase by exposure to substances having an antioxidative effect - also by using tobacco cartridges (so-called Plug-in cigarettes) can be realized, ie by providing a fleece-wrapped tobacco rod and a sleeve with a gas-phase-active filter that the consumer puts together for the finished smoke product (eg cigarette). The addition of antioxidant substances can accordingly take place on the tobacco itself and / or, for example, on the cigarette paper of the sleeve. The present invention therefore also relates to the use of a nonwoven-coated strand of tobacco and / or another smokable material and a filter sleeve which comprises a gas-phase-active filter, for the production of a smokable product according to the invention, the strand of tobacco and / or another smokable material and / or other components accessible to the mainstream smoke being provided with an additive of substances having an antioxidative effect. The present invention also relates to the analogous use of so-called (unfiltered) "plug-in cigarillos" in connection with a filter sleeve which comprises a gas phase active filter for producing a smokable product according to the invention. The present invention therefore also relates to the use of a strand of tobacco and / or another smokable material, which is coated with natural and / or reconstituted tobacco, and a filter sleeve, which comprises a gas phase active filter, for producing a smokable product, whereby the strand of tobacco and / or another smokable material and / or the wrapper of tobacco and / or other components accessible to the mainstream smoke is / are provided with an additive of substances having an antioxidative effect. According to this embodiment, the strand of tobacco and / or another smokable material can alternatively be wrapped with at least two layers of reconstituted tobacco or film tobacco. In these cases, the casing can be both airtight (<1 CU) and airtight (with an air permeability of 5 to 100 CU, preferably 40 to 80 CU) or consist of a combination of airtight envelope tobacco and air-permeable envelope tobacco.

The invention is explained in more detail below with the aid of examples. example 1

Production of experimental ciarettes

For the examinations described in Examples 2 and 3 below, machine-ready test cigarettes were produced at the full flavor level on the basis of the cigarette equipment required for this. A total of 4 different cigarette variants were produced (Tab. 3).

The tocopherol acetate (ToAc) was applied to the cut tobacco in the form of a 20% ethanol solution. The procedure was such that in each case 10 kg of the tobacco were sprayed with the ToAc solution in a rotating treatment drum in the manner known to the person skilled in the art. A dosage of 1.5% ToAc in the tobacco was aimed for. The solvent was then at 22 ° C and 63% rel. Air is vented, at the same time conditioning for cigarette production took place (cigarette versions 1 C and 1 D). The untreated tobacco mixture (cigarette versions 1 A and 1 B) served as a comparison.

The cigarettes were manufactured with two different filters. The gas phase active filters were double filters, the part of the strand side of which consists of a carbon-containing tissue paper (with 30% by weight of microfine ground activated carbon) and the part of the mouth made of cellulose acetate fibers. These filters were referred to in the description as activated carbon filters (AF) and are found in cigarette versions 1 B and 1 C. These conventional cigarette filters were made from cellulose acetate fibers (CA) (cigarette versions 1 A and 1 D). Tab. 3

Overview of the test variants produced

Example 2

Behavior of tocopherol acetate when smoking cigarettes

The behavior of tocopherol acetate (ToAc) when smoking filled flavor cigarettes in the test variants with cellulose acetate filters and with activated carbon filters was investigated.

The cigarettes were smoked according to DIN 10240, the main flow smoke condensate (HSR) being obtained electrostatically. The particle phase of the so-called secondary flow (NSR) was also isolated. For this purpose, 10 test cigarettes were smoked in an 18 m room, lined with V2A steel, so that only the NSR could be distributed in the room. An aliquot of 180 l was then passed through a teflon filter at a flow rate of 3 l / min to separate the particle phase. In addition, the stubs (unused tobacco residues) and the smoked cigarette filters were separated and collected after the cigarettes had been consumed. HSR, NSR, Stummel and the smoked filters were used to produce ethanolic solutions and extracts for analysis on ToAc.

The ToAc was quantified using HPLC with DAD (High Performance Liquid Chromatography with Diode Array Detector). A Purospher RP 18, 5 μm, No548l63 column was used. Methanol was used as the eluent at a flow rate of 1.0 ml / min and a temperature of 35 ° C. The detection took place at 285 nm.

Tab. 4

Transition from tocopherol acetate (ToAc) to mainstream smoke (HSR)

Tab. 4 lists the amounts of HSR condensate (mg / cigarette) and the amounts of ToAc (mg / cigarette) in the HSR condensate for the cigarette variants containing ToAc. 4 is the rel. Share (%) of ToAc in the HSR. The results obtained show that the proportion of ToAc in the HSR condensate (%) for the cigarettes with cellulose acetate filters and carbon filters is at a comparable level, namely on average around 12%. Tab. 5

Recovery of tocopherol acetate after smoking the test cigarettes

Tab. 5 gives an overview of the distribution of the ToAc during smoking or the accounting after the smoking process has been completed. In the second column of Tab. 5 you can find the amounts of ToAc (mg / cigarette) that were present at the start of smoking. This arithmetically results from the amount of tobacco per cigarette and the amount of ToAc added to the tobacco.

In addition, Tab. 5 shows the recovered amounts ToAc (mg / cig.) In HSR, NSR, filter and stub, as well as the resulting sum and the recovered amount (%), based on the amount presented before smoking .

Example 3:

A. General study design to demonstrate the influence of microcirculation

material and methods

1. Test objects:

The following 4 test objects were examined as examples. All test objects were allied for the trial, i.e. it was neither recognizable for the test subjects nor for the investigator which cigarette was smoked. These were cigarettes from the filling flavor segment with the following names in accordance with Example 1:

1 A, 1 B, I C and 1 D

Subjects:

Homogeneous sample, 8 subjects (N = 8); male, Caucasian, moderate smoker; dental and human medical without pathological findings (exception: mild chronic bronchitis); Teeth restored; Defined inclusion and exclusion criteria in accordance with the Good Clinical Practice (GCP) standard (guidelines for the proper clinical trial of medicinal products).

Age: 38 to 43 years (mean 40.5 years) Body mass: 73 to 78 kg (mean 75.3 kg) Body length: 172 to 176 cm (mean 174.1 cm)

3. Definition of inclusion criteria for suitability as a subject:

Male Caucasian, 38 to 43 years old, outpatient; no medication; balanced social status; harmonious marriage; clinically without pathological finding; 4 weeks free of flu infections; no physical or mental disabilities; School leaving certificate at least 10th grade (completed vocational training). Reliability and discipline (strict observance of the examination regulations). Balanced characters (no paranoid or accented personality structures). Moderate smokers (10 to 15 cigarettes daily; approx. 0.9 mg nicotine and approx. 12 mg condensate per cigarette); no alcohol abuse, no drug abuse.

4. Definition of exclusion criteria (not suitable as a subject):

Non-compliance with the inclusion criteria, see above,

5. General exclusion criteria:

Participation in a study (of any kind) in the last 90 days; simultaneous participation in another study. Inability or unwillingness to be able or willing to meet the criteria of the test plan. Alcoholics, drug or drug addicts, neurotics. People with psychiatric disorders. Epilepsy. Risk of suicide. Blood donor or blood loss> 500 ml in the past 6 months. Body mass not within +/- 10% according to size, gender and stature - as in the Metropolitan Life Insurance Company Tables 1983 or Broca Index> 150% or overweight (more than 20% above normal weight). Consumption of abnormal amounts of coffee, tea or tobacco according to the investigator's judgment; Participation in a diet or unbalanced diet according to the judgment of the investigator; irregular (anti-social) lifestyle; possibly contraindication for the planned examinations (from a medical point of view). No declaration of readiness for the investigations. 6. Anamnestic exclusion criteria:

Allergic diathesis; Intolerance or hypersensitivity of any kind; Diabetes melutus; Hyperuricaemia; Hyperthyroidism or other endocrine diseases; chronic or terminal illnesses (carcinoma, tuberculosis); Hypertension; Heart failure, coronary insufficiency; coronary artery disease; Heart valve defects; Myocardial infarction; Stroke; cerebral circulatory disorders TIA (transient ischemic attack; stage Ila of cerebral circulatory disorder); chronic obstructive pulmonary disease COLD; surgery on the intestine; any other chronic illness; Hemodialysis; just a fully functional kidney; Prostate hyperplasia; Blood clotting disorders. Expressed intention to quit smoking.

7. Exclusion criteria to be determined during admission:

Chronic liver disease (elevation of transaminases to twice the normal values); Kidney disease or renal dysfunction (increase in serum creatinine> 1.2 mg% (1.5 mg%) or creatinine clearance 50 - 80 ml / min (<50 ml / min); white blood cell count below 3500 / μl; platelet count below 100,000 / μl. Suspected intestinal dysfunction; suspected pulmonary or bronchial diseases (exception: mild chronic bronchitis). In need of stomatological restoration; lack of more than 2 teeth; periodontal disease, gingivitis.

8. Inadmissible accompanying therapy:

Taking medication or substances within 90 days before the start of the study; non-drug therapy; physical therapy. 9. Secondary exclusion criteria:

Inclusion criteria not met after preliminary examination; Exclusion criteria only determined after inclusion in the study (will be excluded in the context of this study).

10. Boundary conditions for the investigations:

a) Subjects: 12 hours before the examination appointments no alcohol, no coffee, tea or Coca-Cola ®. At least 6 hours of sleep a day; sufficient acclimatization and rest before the measurements (blood pressure RR (measured with Riva-Rocci apparatus) normal, heart rate normal, respiratory rate normal).

b) Measurements: room temperature approx. 22 ° C, relative humidity approx. 75%. Measurements while sitting (head is stored in an ophthalmic attachment during the examination - at the express request of the test subjects). Same time of day (time); same weather conditions.

Study character

Double blind study (determination of the examination procedure by a random generator).

Observation interval, measurement interval

Initial values,

0. minute start of exposure; during and after exposure 2nd minute; 4th minute;

6th minute; 8th minute; 10th minute; 12th minute.

Boundary conditions of the investigations constant (temperature regulation, macro circulation, acclimatization time approx. 2 hours).

Exposure conditions

Orientative framework regarding respiratory rate and tidal volume; when smoking, the subjects retained their usual smoking behavior. Each subject is exposed to all test objects in a series of tests (time interval between exposures> 24 h). The order of the subjects in the experiment and the order of the exposures with the different test objects for each subject is determined by a random generator.

B. Intravital microscopic method (method description, features)

Connected, complete microvessel networks in a target tissue volume of 1 mm with 60 Kirchhoff's nodes (locations of microvessel branches) and mean vessel diameters <40 μm are recorded.

Before each intravital microscopic measured value acquisition, an orienting overview of the complete network in the tissue - target volume is obtained - including its further inflows and outflows, branching geometry and branching hierarchy. Vessel identification, if necessary, is carried out functionally in this study. To display complete microvascular networks in the target area, an intravital microscopic examination unit is used in the combined incident-transmitted light procedure with selective light generators and selective filtering. The primary images obtained are processed and processed with computer assistance (secondary image processing and processing with the KONTRON computer system).

The vital microscopic findings are made under defined lighting and filter conditions; these relate to: spectral distribution of the reflected light and transmitted light components, beam characteristics, angle of incidence of the rearing component, specific filtering of the reflected and penetrating components, emission and absorption spectra of the various structures in the target tissue.

Documentation of the primary images:

Microphotographic snapshots in 35mm, roll film or plate format (NIKON, LINHOF with ARRI adapter; up to 1/8000 sec); Film material up to ISO 3200/36 °).

35mm cine film (color or black and white), complete camera and control system ARRI (up to 120 frames / sec), Agfa special film; automatic Agfa film processing system.

Video recordings (U-matic, Super-VHS; JVC, PANASONIC, BLAUPUNKT, SIEMENS).

The measurement of various geometric and dynamic features of the microcirculation is computer-aided by means of image-to-image analysis; partly in pseudo-color transformation and computer identification of the primary images (computer-assisted histological diagnosis). For intravital microscopic measurements the macrocirculatory boundary conditions must be kept strictly constant and monitored simultaneously.

1 shows the structure of the intravital microscopic examination unit based on a block diagram.

Adaptation of the vital microscopic examination unit with a BAXTFR angioscope glass fiber cable:

The distal part of a BAXTER angioscope (special coronaroscope) is placed in a commercially available sterile O.P. - Swab placed so that buccal fixation of the optical apparatus is guaranteed and at the same time the subject is stressed in a reasonable manner. This procedure is simulated with the test subjects before the start of the study and is accepted by all test persons. Fig. 2 shows a schematic representation of the placement of the distal optical apparatus in the cavu oris of the test subjects.

At the request of the test subjects, an informal fixation of the head by an ophthalmological attachment (jaw rest, forehead rest) is carried out during exposure to the test objects - individually adjusted in a sitting position. When applying the test objects, the test subjects are not prescribed defined exposure conditions; they can proceed in the manner of their habits (train volume, train frequency, number of trains per test object, time).

The following characteristics of the microcirculation are measured:

* Number of currently blood cell-perfused nodes nNP in a defined network unit (specified as absolute values or as percentage changes compared to the initial values). This characteristic describes the assignment of the perfusion states "blood cell perfused" or "not blood cell perfused" according to the following criteria: duration of the state longer than 20 sec; Limit cases are rated with + 0.5 or - 0.5; Limit flow velocity of the red blood cells v ~ 80 μm / s.

* Number of adherent white blood cells on a defined venule inner wall nWBC / A (given as absolute values or as percentage changes compared to the initial values).

This characteristic denotes the number of adherent white blood cells n that adhere to a defined venal inner wall surface A for more than 5 seconds. The reference surface is an area of the inner wall of the venule A = 18000 μm; Average diameter of the venule d = 40 μm, axial venule length 1 = 140 μm.

* Arteriolar and venular flow Q _arc or Q _vβn (given as absolute values or as percentage changes compared to the initial values).

This characteristic describes the flow (current) of the red blood cells, i.e. the particle flow.

The measured values are computer-aided in secondary image processing (KONTRON system). Geometric dimensions within a microvessel (diameter d, radius r) are measured in the normal to the longitudinal axis of the inner endothelial surface to the opposite endothelial inner surface (tangents). This is shown schematically in FIG. 3.

C. Statistical analysis of the measured values

For obvious reasons, a parameter-free test procedure is used. Assuming steady Variables in small but sufficiently large biometric samples are used for the WILCOXON rankings, because with an efficiency of approx. 95% it is one of the strictest parameter-free methods. The tests are carried out at the significance level a = 5%. The critical values of T for the WILCOXON test are taken from: GA Ferguson, Statistical Analysis in Psychology and Education. McGraw-Hill, NY 1959, 318.

For each test object, the initial values are compared with the measured values at the measurement times of 2 minutes to 12 minutes. Furthermore, it is checked whether significantly different characteristic changes occur after exposure of different test objects (comparison of the measured values after exposure of different test objects at the same measurement times).

D. Carrying out the experiment

The subjects are acclimatized before the start of the study and calmed down in a sitting position (thermogrammometric

Monitoring of body shell temperature, measurement of systemic systolic and diastolic blood pressure, general medical

Preliminary examination); then a detailed medical report is given

Preliminary discussion on the current state of the subject (approx. 20 min). The aim of the preliminary medical talks is to:

To prolong the acclimatization period, to further calm the test subject, to establish and consolidate a relationship of trust between the test doctor and test subject (compliance with the boundary conditions and the requirements for the test subject before the start of the examination).

Then, in the laboratory, in a sitting position, the exposure to the respective test object and the findings are carried out as part of a double-blind study.

After the diagnosis has been made, the test subject is asked for a medical follow-up consultation. The follow-up discussion serves the further festivities. establishing the relationship of trust and preparing for the next examination date.

During the follow-up discussion, the test person is also asked about the test object of the exposure, in order to find out whether may have falsified redundant psychological or vegetative-somatic factors of the measurement result due to individual aversion to a specific test object. No evidence of such falsifications was obtained in the context of the present study.

E. Results

The mean values from the measurements with 8 subjects are shown graphically in FIGS. 4 and 5.

FIG. 4 shows an example of the number of blood cell-perfused nodes (nNP) as a function of the time for the cigarette versions 1 A to 1 D according to Example 1.

5 shows the number of adherent white blood cells nWBC / A as a function of the time for the cigarette version 1 A to 1 D according to Example 1.

From Fig. 4 it can be seen that the microperfusion (microcirculation) is determined based on the number of blood cell perfused nodes - in conventional filter cigarettes (1 A) is much more impaired than in the case of gas phase active filters (1 B). As FIG. 4 also shows, exposure to tocopherol acetate (1 D) compared to conventional filter cigarettes also reduces the impairment of the microcirculation to a comparable extent. In filter cigarettes according to the invention, which are distinguished by the combination of a gas-phase-active filter with a tobacco rod (1 C) to which antioxidant substances (here tocopherol acetate) are applied (1 C), there is a further significant mitigation of smoking effects on microcirculation. A few minutes after the end of the exposure, the number of blood cell perfused nodes again increases to the initial value before the exposure.

5 that the number of adherent white blood cells (nWBC / A) as a measure of the immune response when exposed to smoke from conventional filter cigarettes (1A) is significantly higher than in cases in which conventional filter cigarettes with tocopherol acetate (1st D) are applied. In contrast, with filter cigarettes according to the invention which contain gas phase active filters and an addition of substances having an antioxidative effect (here tocopherol, 1 C), the lowest immune response - expressed in number of adherent white blood cells - is observed.

This series of experiments shows that filter cigarettes according to the invention impair the microcirculation significantly less than conventional filter cigarettes and thus represent a significant improvement from a biological-medical point of view with regard to acute effects on the microcirculation.

Example 4

Tobacco treatment with cureumin or ferulic acid ethyl ester

Full-flavor cigarettes, described in Example 1 as version 1A, were used as a comparison to evaluate the active substances cureumin and ferulic acid ethyl ester with regard to their transitions into the HSR and their physiological action, described in Example 5.

The procedure was such that 100 g of cut tobacco, as contained in the 1 A cigarettes, were charged with the ethanoic solutions of cureumin or ethyl ferulate. To

Evaporation of the alcohol was handmade with the tobacco Manufactured cigarettes that corresponded to those of the comparison 1 A in terms of their equipment. The three versions of cigarettes were smoked as described in Example 2.

The treated tobaccos and the condensates of the HSR were then used for analyzes of cureumin or ferulic acid ethyl ester. The analyzes were carried out by means of HPLC as described in Example 2. However, a mixture of water, tetrahydrofuran, acetonitrile and acetic acid was used as the eluent, specifically for cureumin in a ratio of 55/25/20/1 and for ethyl ferulate in a ratio of 77/13/9/1. A Purospher C18 column was used, the detector was set to 420 nm for cureumin and 325 nm for ethyl ferulate.

The following Table 6 shows the concentration of active ingredient (%) that the treated tobacco had and the percentage that was found in the HSR condensate.

Tab. 6

Test objects for example 5

Example 5

The effect of the filter cigarettes produced according to Example 4 on the microcirculation of the oral mucosa of 8 subjects was compared with that in Example 3 (Sections A.2 to D. [methodical Part]) described intravital microscopic test methods examined in a double-bundle experiment.

Test objects:

1 A, B 142 and B 143

Results:

6 shows an example of the number of adherent white blood cells nWBC / A as a function of the time for the filling flavor cigarettes (according to Example 4) with and without the additives cureumin or ethyl ferulate (versions 1A, B 143 and B 142).

From Fig. 6 it can be seen that the immune response - measured as the number of adherent white blood cells (nWBC / A) - when exposed to smoke from conventional filter cigarettes (1 A) is significantly higher than in cases in which conventional filter cigarettes with antioxidative substances such as Cureumin (B 143) or Ferulasäureethylester (B 142) can be applied.

Example 6

An American blend mixture was charged with 2% by weight of tocopherol acetate (based on the amount of tobacco), and the corresponding test and comparative cigarettes were produced as in Example 1.

The sensory result in the expert panel showed a significant reduction in the so-called interference factors such as reactivity, roughness and sharpness in the test cigarettes containing 2% by weight ToAc compared to the comparison cigarettes. Other mixtures (ie using other tobacco mixtures with 2% by weight ToAc) were also checked. In the case of a straight Virginia mixture (cigarette), a significant reduction in the sharpness was also determined, in the case of a pure air cured mixture (cigarillo), a considerable reduction in roughness and reactivity, the typical "cigar-like" side-stream smoke odor of the filter and acted upon according to the invention Cigarillos was rated as less pronounced and less unpleasant than the NSR smell of the comparative cigarillos.

Legend of the figures:

Fig. 1: Block diagram of the intravital microscopic examination unit.

Fig. 2: Schematic representation of the placement of the distal optical apparatus in the cavum oris of the test subjects. In a sterile O.P. -Tab is the fiber optic cable embedded, so that a reasonable fixation between the rack of the right lower jaw and cheek inside is guaranteed.

3: Schematic representation of the interior of a microvessel to illustrate the determination of geometric dimensions.

Fig. 4: Measurement of the number of blood cell-perfusing nodes as a function of the time after the start of exposure in the investigation of conventional and inventive filter cigarettes.

Fig. 5: Measurement of the number of adherent white blood cells as a function of the time after the start of exposure when examining conventional and inventive filter cigarettes.

Fig. 6: Measurement of the number of adherent white blood cells as a function of the time after the start of exposure in tests for filling flavor cigarettes with and without additives.

REPLACEMENT SHEET RULE 26

Claims

Claims:

Smokable product, characterized in that it

a) contains a gas phase active filter and / or gas phase active cigarette paper and / or one or more other components accessible to the mainstream smoke contain an additive of gas phase active substances and

b) the strand of tobacco and / or another smokable material and / or other components accessible to the mainstream smoke is / are provided with an additive of substances having an antioxidative effect.

Smokable product according to claim 1, characterized in that it is a filter cigarette, a filter cigarillo or a filtered cigar.

Smokable product according to claim 1 or 2, characterized in that the filter contains 5 to 65% by weight of a surface-rich material.

Smokable product according to Claim 3, characterized in that the filter contains 20 to 50% by weight of a surface-rich material.

Smokable product according to claim 4, characterized in that the filter contains 30% by weight of a surface-rich material.

Smokable product according to claims 1 to 5, characterized in that the filter contains means for introducing ventilation air.

7. Smokable product according to claims 1 to 6, characterized in that the filter has at least one circumferential filter ventilation zone in the mouth-side part.

8. Smokable product according to claims 1 to 7, characterized in that the degree of filter ventilation is 5 to 95%.

9. Smokable product according to claim 8, characterized in that the degree of filter ventilation is 25 to 75%.

10. Smokable product according to claims 1 to 9, characterized in that the product contains a tobacco rod coated with cigarette paper or a tobacco rod coated with non-woven paper and cigarette paper, in which the air permeability of the cigarette paper is 10 to 100 CU, and in which the air permeability of the Nonwoven paper is 4000 to 60 000 CU.

11. Smokable product according to claim 10, characterized in that the air permeability of the cigarette paper is 20 to 60 CU.

12. Smokable product according to claims 1 to 11, characterized in that the filter is a chamber filter, a litter filter, a monobloc filter, a double filter, a core filter or a multifilter, the multifilter being any combination of filters from the Group consisting of chamber filters, litter filters, monobloc filters and / or core filters.

13. Smokable product according to claim 12, characterized in that the filters are channel-ventilated and / or have a mouth-side recess filter section and / or a mouth-side core filter.

14. Smokable product according to claim 2, characterized in that it is a filter cigarette with a tobacco rod surrounded by a cigarette paper, in which the filter is a double filter or a multifilter, the strand-side part of which consists of a tissue paper which is 5 to 65% by weight. % of a surface-rich material contains.

15. Smokable product according to claim 2, characterized in that it is a filter cigarette with a tobacco rod surrounded by a cigarette paper, in which the filter is a monofilter consisting of a tissue paper which contains 5 to 65 wt .-% of a surface-rich material .

16. Smokable product according to claims 13 to 15, characterized in that the tissue paper contains 20 to 50 wt .-% of a surface-rich material.

17. Smokable product according to claim 16, characterized in that the tissue paper contains 30 wt .-% of a surface-rich material.

18. Smokable product according to claims 13 to 17, characterized in that the filter has a circumferential filter ventilation zone in the mouth-side part, the tissue paper of the strand-side filter part is a very voluminous paper, the air permeability of the cigarette paper is 10 to 100 CU and the degree of filter ventilation is 5 to 95%.

19. Smokable product according to claim 18, characterized in that the air permeability of the cigarette paper is 20 to 60 CU.

20. Smokable product according to claim 18 or 19, characterized in that the degree of filter ventilation is 25 to 75%.

21. Smokable product according to claims 13 to 20, characterized in that the strand-side part of the filter is a core filter with a core of tissue paper according to one of the preceding claims, which is surrounded by a jacket of material which is almost impermeable to the mainstream smoke.

22. Smokable product according to claims 1 to 21, characterized in that the gas-phase-active filter and / or the gas-phase-active cigarette paper and / or the components accessible to the mainstream smoke each have surface-rich material from the group consisting of activated carbon, aluminum oxide, aluminum hydroxide, bentonite, cellulose, Diatomaceous earth, ion exchangers, light metal salts, meerschaum, molecular sieves, silica gels, clays, zeolites or combinations thereof.

23. Smokable product according to claim 22, characterized in that the surface-rich material is activated carbon, meerschaum or Siücagel.

24. Smokable product according to claim 22 or 23, characterized in that the surface-rich material has a grain size of 2 mm or less and has an inner specific surface in the range from 50 m ² / g to 2000 m Ig.

25. Smokable product according to claim 24, characterized in that the grain size is 15 microns to 2 mm or less than 15 microns.

26. Smokable product according to claims 1 or 2, characterized in that it is a filter cigarette

a) a tobacco rod surrounded by a cigarette paper with an air permeability of 20 to 100 CU or one by a cigarette paper with an air permeability contains from 20 to 100 CU of fleece-wrapped tobacco rod, and

b) contains a double filter with a degree of filter ventilation of 5 to 95%, the strand-side part of which consists of a very voluminous tissue paper containing 5 to 65% by weight of microfine ground activated carbon, and which in the mouth-side part is provided with a filter ventilation zone running in the circumferential direction is.

27. Smokable product according to claim 26, characterized in that the tissue paper contains 20 to 50 wt .-% of a surface-rich material.

28. Smokable product according to claims 1 to 27, characterized in that the tobacco rod is provided with an addition of more than 0.1% by weight of antioxidative substances.

29. Smokable product according to claim 28, characterized in that the tobacco rod is provided with an addition of more than 0.1 wt .-% to 5 wt .-% of antioxidative substances.

30. Smokable product according to claim 29, characterized in that the tobacco rod is provided with an addition of more than 0.5 wt .-% to 4 wt .-% of antioxidative substances.

31. Smokable product according to claim 30, characterized in that the tobacco rod is provided with an addition of 1 to 2.5% by weight of antioxidative substances.

32. Smokable product according to claims 1 to 31, characterized in that the antioxidative substances from the group consisting of ascorbic acid, β-carotene, retinol, tocopherol, their derivatives and precursors, eugenol, jasmine aldehyde, cinnamon, cinnamon extract, (raw -) Coffee, (raw) coffee extract, methyl caffeic acid, ethyl cesate, methyl ferulate, ethyl ferulate, umbelliferone, scopoline and cureumin are selected, the substances being added to the tobacco either individually or in combination with one another.

33. Smokable product according to claim 32, characterized in that the antioxidative substance is α-tocopherol, tocopherol acetate and / or tocopherol succinate.

34. Smokable product according to claims 1 to 33, characterized in that the tobacco rod is provided with further additives in auxiliaries, fillers and flavorings.

35. Smokable product according to claim 1 or 2, characterized in that it is a filter cigarette which contains a tobacco rod covered by a cigarette paper with an air permeability of 40 to 60 CU, the non-woven paper being a highly porous non-woven paper with an air permeability of 32 000 CU , and whose filter is a double filter with a degree of filter ventilation of about 20 to about 25%, the part of the strand side of which consists of a very voluminous tissue paper containing 30% by weight, microfine ground activated carbon, which is provided with a circumferential filter ventilation zone , which consists of cellulose acetate in the mouth-side part, the tobacco rod being provided with an addition of about 2% tocopherol acetate.

36. Smokable product according to claim 1 or 2, characterized in that it is a filter cigarette which contains a tobacco rod wrapped by a cigarette paper with an air permeability of 40 to 60 CU, the non-woven paper being a highly porous non-woven paper with an air permeability of 32 000 CU , and whose filter is a double filter with a degree of filter ventilation of about 50%, the strand-side part of which consists of a very voluminous tissue paper containing 30% by weight, microfine ground activated carbon, which is provided with a circumferential filter ventilation zone which in the mouth-side part consists of cellulose acetate, the tobacco rod being provided with an addition of about 2% tocopherol acetate.

37. Smokable product according to claim 1 or 2, characterized in that it is a filter cigarette which contains a tobacco rod covered by a cigarette paper with an air permeability of 40 to 60 CU, the non-woven paper being a highly porous non-woven paper with an air permeability of 32 000 CU , and the filter of which is a double filter with a degree of filter ventilation of approximately 60 to approximately 75%, the part of the strand side of which consists of a very voluminous tissue paper containing 30% by weight of microfine ground activated carbon, which is provided with a filter ventilation zone running in the circumferential direction , which consists of cellulose acetate in the mouth-side part, the tobacco rod being provided with an addition of about 2% tocopherol acetate.

38. Smokable product according to claims 1 to 34, characterized in that it is a filter cigarette, the tobacco rod is coated with two layers of cigarette paper, the inner layer consisting of a sidestream smoke-reducing cigarette paper of low air permeability and the outer layer of a flavored cigarette paper with an air permeability of 20 to 100 CU.

39. Smokable product according to claim 38, characterized in that the flavored cigarette paper has an air permeability of 40 to 80 CU.

40. Smokable product according to claims 1 to 34, characterized in that it is a filter cigarillo with a sheet of air-permeable or air-impermeable film tobacco and a cover sheet of natural tobacco and a chamber filter, the central chamber of which is filled with activated carbon.

41. Use of a fleece-wrapped strand of tobacco and / or another smokable material and a filter sleeve, which comprises a gas phase active filter, for producing a smokable product according to claims 1 to 39, characterized in that the strand of tobacco and / or another smokable material and / or other components accessible to the mainstream smoke is / are provided with an additive of substances having an antioxidative effect.

42. Use of a strand of tobacco and / or another smokable material, which is coated with natural and / or reconstituted tobacco, and a filter sleeve, which comprises a gas phase active filter, for producing a smokable product according to claims 1 to 34 and 40, characterized in that the strand of tobacco and / or another smokable material and / or the casing of tobacco and / or other components accessible to the mainstream smoke is / are provided with an additive of substances having an antioxidative effect.

43. Use of a strand of tobacco and / or another smokable material, which is coated with at least two layers of reconstituted tobacco or foil tobacco, and a filter sleeve, which comprises a gas phase active filter, for producing a smokable product according to claims 1 to 34 and 40, characterized in that the strand of tobacco and / or another smokable material and / or at least one wrapper made of tobacco and / or other components accessible to the mainstream smoke is / are provided with an additive of substances having an antioxidative effect.

44. Use according to claim 42 or 43, characterized in that the covering is air-impermeable or air-permeable or consists of a combination of air-impermeable tobacco and air-permeable wrapping tobacco.