EP1173468A1 - Integrin receptor antagonists - Google Patents

Integrin receptor antagonists

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Publication number
EP1173468A1
EP1173468A1 EP00926971A EP00926971A EP1173468A1 EP 1173468 A1 EP1173468 A1 EP 1173468A1 EP 00926971 A EP00926971 A EP 00926971A EP 00926971 A EP00926971 A EP 00926971A EP 1173468 A1 EP1173468 A1 EP 1173468A1
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Prior art keywords
gly
bala
bhs
phhs
tolhs
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EP00926971A
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German (de)
French (fr)
Inventor
Andreas Kling
Udo Lange
Arnulf Lauterbach
Hervé Geneste
Thomas Subkowski
Johann-Christian Zechel
Claudia Isabella Graef
Wilfried Hornberger
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Abbott GmbH and Co KG
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BASF SE
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Priority claimed from DE1999119218 external-priority patent/DE19919218A1/en
Priority claimed from DE1999148269 external-priority patent/DE19948269A1/en
Application filed by BASF SE filed Critical BASF SE
Publication of EP1173468A1 publication Critical patent/EP1173468A1/en
Withdrawn legal-status Critical Current

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Abstract

The invention relates to new compounds which bind to integrin receptors, as well as to their production, their use as integrin receptor antagonists and for the treatment of diseases, pharmaceutical preparations containing said compounds and pharmaceutical preparations containing at least one other active compound.

Description

Integrinrezeptorantagonisten Integrin receptor antagonists
Beschreibung 5Description 5
Die Erfindung betrifft neue Verbindungen, die an Integrin- rezeptoren binden, deren Herstellung und Verwendung.The invention relates to new compounds that bind to integrin receptors, their production and use.
Integrine sind Zelloberflächen-Glycoproteinrezeptoren, die 10 Wechselwirkungen zwischen gleichartigen und unterschiedlichen Zellen sowie zwischen Zellen und extrazellulären Matrixproteinen vermitteln. Sie sind an physiologischen Prozessen, wie z.B. Embryogenese, Hämostase, Wundheilung, Immunantwort und Bildung/ Aufrechterhaltung der Gewebearchitektur beteiligt. 15Integrins are cell surface glycoprotein receptors that mediate 10 interactions between similar and different cells as well as between cells and extracellular matrix proteins. They are involved in physiological processes such as Embryogenesis, hemostasis, wound healing, immune response and formation / maintenance of tissue architecture are involved. 15
Störungen in der Genexpression von Zelladhäsionsmolekülen sowie Funktionsstörungen der Rezeptoren können zur Pathogenese vieler Erkrankungen, wie beispielsweise Tumore, thromboembolische Ereignisse, kardiovaskuläre Erkrankungen, Lungenkrankheiten, 20 Erkrankungen des ZNS, der Niere, des Gastrointestinaltraktes oder Entzündungen beitragen.Disorders in the gene expression of cell adhesion molecules and functional disorders of the receptors can contribute to the pathogenesis of many diseases, such as tumors, thromboembolic events, cardiovascular diseases, lung diseases, 20 diseases of the CNS, the kidney, the gastrointestinal tract or inflammation.
Integrine sind Heterodimere aus jeweils einer α- und einer ß-Transmembran-Untereinheit, die nicht-kovalent verbunden sind. 25 Bisher wurden 16 verschiedene α- und 8 verschiedene ß-Unter- einheiten und 22 verschiedene Kombinationen identifiziert.Integrins are heterodimers each consisting of an α and a β transmembrane subunit, which are non-covalently linked. 25 So far, 16 different α and 8 different β subunits and 22 different combinations have been identified.
Integrin αvß3/ auch Vitronectinrezeptor genannt, vermittelt die Adhäsion an eine Vielzahl von Liganden - Plasmaproteine, extra-Integrin α v ß 3 / also called vitronectin receptor, mediates the adhesion to a variety of ligands - plasma proteins, extra-
30 zelluläre Matrixproteine, Zelloberflächenproteine -, von denen der Großteil die Aminosäuresequenz RGD enthält (Cell, 1986, 44, 517-518; Science 1987, 238, 491-497), wie beispielsweise Vitronectin, Fibrinogen, Fibronectin, von Willebrand Faktor, Thrombospondin, .Osteopontin, Laminin, Collagen, Thrombin,30 cellular matrix proteins, cell surface proteins - the majority of which contain the amino acid sequence RGD (Cell, 1986, 44, 517-518; Science 1987, 238, 491-497), such as, for example, Vitronectin, Fibrinogen, Fibronectin, von Willebrand Faktor, Thrombospondin, .Steopontin, laminin, collagen, thrombin,
35 Tenascin, MMP-2, bone-sialo-Protein II, verschiedene virale, parasitäre und bakterielle Proteine, natürliche Integrin-Anta- gonisten wie Disintegrine, Neurotoxine - Mambin - und Blutegelproteine - Decorsin, Ornatin - sowie einige nicht-RGD-Liganden, wie beispielsweise Cyr-61, PECAM (L. Piali, J. Cell Biol. 1995,35 tenascin, MMP-2, bone sialo protein II, various viral, parasitic and bacterial proteins, natural integrin antagonists such as disintegrins, neurotoxins - mambin - and leech proteins - decorsin, ornatin - and some non-RGD ligands, such as Cyr-61, PECAM (L. Piali, J. Cell Biol. 1995,
40 130, 451-460; Buckley, J. Cell Science 1996, 109, 437-445, J. Biol. Chem. 1998, 273, 3090-3096).40 130, 451-460; Buckley, J. Cell Science 1996, 109, 437-445, J. Biol. Chem. 1998, 273, 3090-3096).
Mehrere Integrinrezeptoren zeigen Kreuzreaktivität mit Liganden, die das RGD-Motiv enthalten. So erkennt Integrin αnbß3, auch 45 Plättchen-Fibrinogen-Rezeptor genannt, Fibronectin, Vitronectin, Thrombospondin, von Willebrand Faktor und Fibrinogen. Integrin αvß3 ist u.a. exprimiert auf Endothelzellen, Blut- plättchen, Monocyten/Makrophagen, Glattmuskelzellen, einigen B-Zellen, Fibroblasten, Osteoclasten und verschiedenen Tumorzellen, wie beispielsweise Melanome, Glioblastome, Lungen-, Brust-, Prostata- und Blasenkarzinome, Osteosarkome oder Neuro- blastome.Several integrin receptors show cross-reactivity with ligands that contain the RGD motif. Integrin αn b ß 3 , also called 45 platelet fibrinogen receptor, recognizes fibronectin, vitronectin, thrombospondin, von Willebrand factor and fibrinogen. Integrin α v ß 3 is expressed, inter alia, on endothelial cells, platelets, monocytes / macrophages, smooth muscle cells, some B cells, fibroblasts, osteoclasts and various tumor cells, such as melanomas, glioblastomas, lung, breast, prostate and bladder carcinomas, Osteosarcomas or neuroblastomas.
Eine erhöhte Expression beobachtet man unter verschiedenen pathologischen Bedingungen, wie beispielsweise im prothrombotischen Zustand, bei Gefäßverletzung, Tumorwachstum oder -metastasierung oder Reperfusion und auf aktivierten Zellen, insbesondere auf Endothelzellen, Glattmuskelzellen oder Makrophagen.An increased expression is observed under various pathological conditions, such as in the prothrombotic state, in the case of vascular injury, tumor growth or metastasis or reperfusion and on activated cells, in particular on endothelial cells, smooth muscle cells or macrophages.
Eine Beteiligung von Integrin 0vß3 ist unter anderem bei folgenden Krankheitsbildern nachgewiesen:Integrin 0 v ß 3 has been shown to be involved in the following clinical pictures, among others:
Kardiovaskuläre Erkrankungen wie Atherosklerose, Restenose nach Gefäßverletzung, und Angioplastie (Neointimabildung, Glattmuskelzeilmigration und Proliferation) (J. Vase. Surg. 1994, 19, 125-134; Circulation 1994, 90, 2203-2206),Cardiovascular diseases such as atherosclerosis, restenosis after vascular injury, and angioplasty (neointima formation, smooth muscle line migration and proliferation) (J. Vase. Surg. 1994, 19, 125-134; Circulation 1994, 90, 2203-2206),
akutes Nierenversagen (Kidney Int. 1994, 46, 1050-1058; Proc.acute kidney failure (Kidney Int. 1994, 46, 1050-1058; Proc.
Natl. Acad. Sei. 1993, 90, 5700-5704; Kidney Int. 1995, 48,Natl. Acad. Be. 1993, 90, 5700-5704; Kidney Int. 1995, 48,
1375-1385) ,1375-1385),
Angiogenese-assoziierte Mikroangiopathien wie beispielsweise diabetische Retinopathie oder rheumatische Arthritis (Ann. Rev.Angiogenesis-associated microangiopathies such as diabetic retinopathy or rheumatic arthritis (Ann. Rev.
Physiol 1987, 49, 453-464; Int. Ophthalmol. 1987, 11, 41-50,- CellPhysiol 1987, 49, 453-464; Int. Ophthalmol. 1987, 11, 41-50, - Cell
1994, 79, 1157-1164; J. Biol. Chem. 1992, 267, 10931-10934),1994, 79, 1157-1164; J. Biol. Chem. 1992, 267, 10931-10934),
arterielle Thrombose,arterial thrombosis,
Schlaganfall (Phase II Studien mit ReoPro, Centocor Inc. , 801 annual European Stroke Meeting) ,Stroke (phase II studies with ReoPro, Centocor Inc., 8 01 annual European Stroke Meeting),
Krebserkrankungen, wie beispielsweise bei der Tu ormetastasierung oder beim Tumorwachstum (tumorinduzierte Angiogenese) (Cell 1991, 64, 327-336; Nature 1989, 339, 58-61; Science 1995, 270, 1500-1502),Cancer, such as tumor metastasis or tumor growth (tumor-induced angiogenesis) (Cell 1991, 64, 327-336; Nature 1989, 339, 58-61; Science 1995, 270, 1500-1502),
Osteoporose (Knochenresorption nach Proliferation, Chemotaxis und Adhäsion von Osteoclasten an Knochenmatrix) (FASEB J. 1993, 7, 1475-1482; Exp. Cell Res. 1991, 195, 368-375, Cell 1991, 64, 327-336) , Bluthochdruck, Psoriasis, Hyperparathyroismus, Paget'sche Erkrankung, maligne Hypercalcemie, metastatische osteolytische Läsionen, Entzündung, Herzinsuffizienz, CHF, sowie beiOsteoporosis (bone resorption after proliferation, chemotaxis and adhesion of osteoclasts to bone matrix) (FASEB J. 1993, 7, 1475-1482; Exp. Cell Res. 1991, 195, 368-375, Cell 1991, 64, 327-336), Hypertension, psoriasis, hyperparathyroism, Paget's disease, malignant hypercalcemia, metastatic osteolytic lesions, inflammation, heart failure, CHF, and in
anti-viraler, anti-parasitärer oder anti-bakterieller Therapie und Prophylaxe (Adhäsion und Internalisierung) .anti-viral, anti-parasitic or anti-bacterial therapy and prophylaxis (adhesion and internalization).
Aufgrund seiner Schlüsselrolle sind pharmazeutische Zubereitungen, die niedermolekulare Integrin ovß3 Antagonisten enthalten, u.a. in den genannten Indikationen von hohem therapeutischen bzw. diagnostischen Nutzen.Because of its key role, pharmaceutical preparations containing low-molecular integrin or 3 antagonists are of great therapeutic or diagnostic use, inter alia, in the indications mentioned.
Vorteilhafte Ovß3-Integrinrezeptorantagonisten binden an den Integrin 0Cvß3 Rezeptor mit einer erhöhten Affinität.Advantageous O v ß 3 integrin receptor antagonists bind to the integrin 0C v ß 3 receptor with an increased affinity.
Besonders vorteilhafte ctvß3-Integrinrezeptorantagonisten weisen gegenüber dem Integrin αvß3 zusätzlich eine erhöhte Selektivität auf und sind bezüglich des Integrins 0Cnß3 mindestens um den Faktor 10 weniger wirksam, bevorzugt mindestens um den Faktor 100.Particularly advantageous ct v ß 3 integrin receptor antagonists have an increased selectivity compared to the integrin α v ß 3 and are less effective with respect to the integrin 0Cnß 3 by at least a factor of 10, preferably at least by a factor of 100.
Für eine Vielzahl von Verbindungen, wie anti-θtvß3 monoklonale Antikörper, Peptide, die die RGD-Bindungssequenz enthalten, natürliche, RGD-enthaltenden Proteine (z.B. Disintegrine) und niedermolekulare Verbindungen ist eine Integrin θvß3 antagonistische Wirkung gezeigt und ein positiver in vivo Effekt nachgewiesen worden (FEBS Letts 1991, 291, 50-54; J. Biol. Chem. 1990, 265, 12267-12271; J. Biol. Chem. 1994, 269, 20233-20238; J. Cell Biol 1993, 51, 206-218; J. Biol. Chem. 1987, 262, 17703-17711; Bioorg. Med. Chem. 1998, 6, 1185-1208).For a large number of compounds, such as anti-θt v ß 3 monoclonal antibodies, peptides which contain the RGD binding sequence, natural, RGD-containing proteins (eg disintegrins) and low molecular weight compounds, an integrin θ v ß 3 antagonistic effect is shown and a positive in vivo effect has been demonstrated (FEBS Letts 1991, 291, 50-54; J. Biol. Chem. 1990, 265, 12267-12271; J. Biol. Chem. 1994, 269, 20233-20238; J. Cell Biol 1993 , 51, 206-218; J. Biol. Chem. 1987, 262, 17703-17711; Bioorg. Med. Chem. 1998, 6, 1185-1208).
WO 9708145 beschreibt meta-Guanidino-, Harnstoff-, Thioharnstoff- oder azacyclische Aminobenzoesäurederivate und ihre Verwendung als αvß3-Integrinrezeptorantagonisten.WO 9708145 describes meta-guanidino, urea, thiourea or azacyclic aminobenzoic acid derivatives and their use as αvß 3 integrin receptor antagonists.
Der Erfindung lag die Aufgabe zugrunde, neue Integrinrezeptor- antagonisten mit vorteilhaften Eigenschaften zur Verfügung zu stellen. Dementsprechend wurden Verbindungen der Formel I gefunden,The object of the invention was to provide new integrin receptor antagonists with advantageous properties. Accordingly, compounds of the formula I were found
A—E-G—L IA-E-G-L I
wobei A, E, G und L folgende Bedeutung haben:where A, E, G and L have the following meaning:
L ein Strukturelement der Formel IL L is a structural element of the formula I L
wobei in which
a 0 oder 1,a 0 or 1,
T eine Gruppe COOH oder einen zu COOH hydrolysierbaren Rest,T is a group of COOH or a radical which can be hydrolyzed to COOH,
R2 Wasserstoff, NHS02R21, NHCOR21 oder NHCOOR22,R 2 is hydrogen, NHS0 2 R 21 , NHCOR 21 or NHCOOR 22 ,
wobeiin which
R21 einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cβ-Alkyl-, C3-C6-Cycloalkyl-,R 21 is a branched or unbranched, optionally substituted Ci-Cβ-alkyl-, C 3 -C 6 -cycloalkyl-,
Cι-C4-Alkyl-C3-C5-Cycloalkylrest, C5-C1-Bicycloalkyl- oder Cg-Ciβ-Tricycloalkylrest, einen mit bis zu drei gleichen oder verschiedenen Resten substituierten Aryl-, Alkylaryl-, Alkylheteroarylrest oder 3- bis 6 gliedrigen, gesättigten, ungesättigten oder aromatischen Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome O, N, S enthalten kann, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbo- cyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und dieser Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann,C 1 -C 4 alkyl-C 3 -C 5 cycloalkyl radical, C 5 -C 1 bicycloalkyl or Cg-Ciβ-tricycloalkyl radical, an aryl, alkylaryl, alkyl heteroaryl radical substituted with up to three identical or different radicals or 3- to 6-membered, saturated, unsaturated or aromatic heterocycle, which can contain up to three different or identical heteroatoms O, N, S, where two radicals together form a fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different ones or may contain identical heteroatoms 0, N, S, and this cycle may optionally be substituted or another, optionally substituted, saturated, unsaturated or aromatic cycle may be fused onto this cycle,
R22 einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cδ-Alkylrest oder einen gegebenen- falls substituierten Aryl- oder Alkylarylrest, R3 Wasserstoff oder - (CH2)b-(X)c-R31,R22 is a branched or unbranched, optionally substituted Ci-C δ -alkyl radical or an optionally substituted aryl or alkylaryl, R 3 is hydrogen or - (CH 2 ) b - (X) c -R 31 ,
wobeiin which
b 0, 1, 2 oder 3,b 0, 1, 2 or 3,
c 0 oder 1,c 0 or 1,
X -S0-, -S-, -0-, -CO-, -NH-S02-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R31)-, -N(R31)-CO-, -S02-NH-,X -S0-, -S-, -0-, -CO-, -NH-S0 2 -, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO -N (R 31 ) -, -N (R 31 ) -CO-, -S0 2 -NH-,
-S02-N(R31)- oder -N(R31) -S02-,-S0 2 -N (R 31 ) - or -N (R 31 ) -S0 2 -,
R31 Wasserstoff, eine Hydroxygruppe, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cδ-Alkyl-, Cι-C4-Alkoxy, -O-Alkylaryl- oder -0-R 31 is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted Ci-C δ- alkyl, -C-C 4 alkoxy, -O-alkylaryl or -0-
Arylrest, einen primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest, einen gegebenenfalls mit Cχ-C4-Alkyl oder Aryl substituierten C2-C6-Alkinyl- oder C-C6~Alkenylrest, einen C5-Cι2-Bicycloalkyl-, Cδ-Cis-Tricycloalkylrest oder einen mit bis zu drei gleichen oder verschiedenen Resten substituierten, 3- bis 6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S ent- halten kann, C3_8-Cycloalkyl-, Aryl- oder Heteroaryl- rest, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbo- cyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann,Aryl group, a primary or optionally secondary or tertiary substituted amino group, a C optionally with Cχ-C 4 alkyl or aryl substituted 2 -C 6 alkynyl or C ~ 6 alkenyl group, a C 5 -Cι 2 bicycloalkyl, C δ -Cis-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle substituted with up to three identical or different radicals, which can contain up to three different or identical heteroatoms 0, N, S, C 3 _ 8 - Cycloalkyl, aryl or heteroaryl radical, where two radicals together can form an fused, saturated, unsaturated or aromatic carbocycle or heterocycle which can contain up to three different or identical heteroatoms 0, N, S and the cycle if appropriate substituted or another, optionally substituted, saturated, unsaturated or aromatic cycle may be fused onto this cycle,
undand
R4 Wasserstoff , oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι_4-Alkyl- , C3-C6-Alkenyl- , C3-C6-Alkinyl- oder C3-C6-Cycloalkyl- rest,R 4 is hydrogen, or a branched or unbranched, optionally substituted C 4 alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl or C 3 -C 6 cycloalkyl radical,
bedeuten, G ein Strukturelement der Formel IG mean, G is a structural element of the formula I G
wobei in which
d 0, 1 oder 2,d 0, 1 or 2,
R5 Wasserstoff, eine Hydroxygruppe, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cß-Alkyl-, Cι-C4-Alkoxy, -O-Alkylaryl- oder -O-Arylrest, einen primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest, einen gegebenenfalls mit Cι-C4-Alkyl oder Aryl substituierten C2-C6~Alkinyl- oder C2-Cg-Alkenylrest, einen C5-Cι2-Bicycloalkyl-, Cδ-Cig-Tricycloalkylrest oder einen mit bis zu drei gleichen oder verschiedenenR 5 is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted Ci-C ß- alkyl, -C-C 4 alkoxy, -O-alkylaryl or -O-aryl radical, a primary or optionally secondary or tertiary substituted amino radical, a C 2 -C 6 -alkynyl or C 2 -Cg alkenyl radical optionally substituted with C 1 -C 4 alkyl or aryl, a C 5 -C 2 bicycloalkyl, C δ -Cig tricycloalkyl radical or one with up to three same or different
Resten substituierten, 3- bis 6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, C3-Cs-Cycloalkyl-, Aryl- oder Hetero- arylrest, wobei zwei Reste zusammen einen gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substi- tuiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann, oder die Seitenkette einer natürlichen Aminosäure,Residues substituted, 3- to 6-membered, saturated or unsaturated heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, C 3 -Cs cycloalkyl, aryl or hetero aryl radical, two radicals together being one saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, and the cycle is optionally substituted or another, optionally substituted, saturated, unsaturated or aromatic cycle on this cycle can be condensed, or the side chain of a natural amino acid,
R6 Wasserstoff, oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-, C3-C6-Alkenyl-, C3-C6-Alkinyl- oder C3-C6-Cycloalkyl- rest bedeuten,R 6 is hydrogen, or a branched or unbranched, optionally substituted C 1 -C 4 -alkyl, C 3 -C 6 -alkenyl, C 3 -C 6 -alkynyl or C 3 -C 6 -cycloalkyl radical,
E ein Strukturelement der Formel IE E is a structural element of the formula I E
- (NH) g- (CH2 ) f-Q- (CH2 ) e-C0- IE- (NH) g - (CH 2 ) f -Q- (CH 2 ) e -C0- IE
wobei e 0, 1 oder 2,in which e 0, 1 or 2,
f 0 oder 1,f 0 or 1,
g 0 oder 1,g 0 or 1,
Q ein zweifach gebundener, gegebenenfalls substituierter Heteroarylrest, wobei zwei Substituenten zusammen einen gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättig- ter oder aromatischer Cyclus ankondensiert sein kann,Q is a double-bonded, optionally substituted heteroaryl radical, where two substituents together can represent a saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, and the cycle optionally substituted or on this cycle a further, optionally substituted, saturated, unsaturated or aromatic cycle can be fused on,
A eines der Strukturelemente der Formeln IA 1 bis IA 20 A one of the structural elements of the formulas I A 1 to I A 20
wobei in which
Rio, Rii unabhängig voneinander Wasserstoff, - (CH2) ~ (Y)i-R101, oder beide Reste zusammen einen 3 bis 8 gliedrigen, gegebenenfalls substituierten, gesättigten, ungesättigten oder aromatischen N-Heterocyclus der zusätzlich zwei weitere, gleiche oder verschiedene Heteroatome O, N oder S enthalten kann,R i o, R ii independently of one another hydrogen, - (CH 2 ) ~ (Y) iR 101 , or both radicals together form a 3 to 8-membered, optionally substituted, saturated, unsaturated or aromatic N-heterocycle of the two additional, identical or can contain different heteroatoms O, N or S,
wobeiin which
h 0, 1, 2 oder 3,h 0, 1, 2 or 3,
i 0 oder 1,i 0 or 1,
Y -S02-, -S-, -0-, -CO-, -NH-S02-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R101)-, -N(R101) -CO-, -S02-NH-, -N(R101)-SO2- oder -S02-N(R101) - undY -S0 2 -, -S-, -0-, -CO-, -NH-S0 2 -, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, - CO-N (R 101 ) -, -N (R 101 ) -CO-, -S0 2 -NH-, -N (R 101 ) -SO 2 - or -S0 2 -N (R 101 ) - and
R101 eine Hydroxygruppe, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C6-Alkyl-, Cι-C4-Alkoxy, -O-Alkylaryl- oder -O-Arylrest, einen primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest, einen gegebenenfalls mit Cι-C4-Alkyl oder Aryl substituierten C2-C6~Alkinyl- oder C2-C6-Alkenylrest, einen C5-Cι2-Bicycloalkyl-, Cε-Cig-Tricycloalkylrest oder einen mit bis zu drei gleichen oder verschiedenen Resten substituierten, 3- bis 6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, C3_8-Cycloalkyl-, Aryl- oder Heteroarylrest, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann,R 101 is a hydroxyl group, a branched or unbranched, optionally substituted C 1 -C 6 -alkyl, C 1 -C 4 alkoxy, -O-alkylaryl or -O-aryl radical, a primary or optionally secondary or tertiary substituted amino radical, one optionally with C 1 -C 4 alkyl or aryl substituted C 2 -C 6 ~ alkynyl or C 2 -C 6 alkenyl radical, a C 5 -C 2 bicycloalkyl, Cε-Cig tricycloalkyl radical or one with up to three of the same or different radicals substituted, 3- to 6-membered, saturated or unsaturated heterocycle containing up to three different or identical heteroatoms 0, N, which may contain S, C 3 _ 8 cycloalkyl, aryl or heteroaryl, where two radicals together form an annealed , saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, and the cycle optionally substituted or another, optionally on this cycle substituted, saturated, unsaturated or aromatic cycle can be fused on,
R12 einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι~C4-Alkyl-, Alkylaryl-, C3-C6-Cyclo- alkyl- oder Cι-C4-Alkyl-C3-C6-Cycloalkylrest oder einen gegebenenfalls substituierten Arylrest, R13 Wasserstoff, -OH, -CN, -CONH2, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-, Cι-C4-Alkoxy- oder -OCO-Cι-C4~Alkylrest, oder einen gegebenfalls substituierten Alkylaryl-, -O-Alkylaryl-, -OCO-Aryl-, -OCO-Alkylaryl- oder -OCO-Allylrest,R 12 is a branched or unbranched, optionally substituted C 1 -C 4 alkyl, alkylaryl, C 3 -C 6 cycloalkyl or C 1 -C 4 alkyl C 3 -C 6 cycloalkyl radical or an optionally substituted aryl radical , R 13 is hydrogen, -OH, -CN, -CONH 2 , a branched or unbranched, optionally substituted C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy or -OCO-C 4 -C 4 alkyl radical, or an optionally substituted one Alkylaryl, -O-alkylaryl, -OCO-aryl, -OCO-alkylaryl or -OCO-allyl radical,
R14 Wasserstoff, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cχ-C4-Alkyl-, Alkylaryl-, -C02-C1_4-Alkyl-, -C02-Alkylaryl-, -C02-Allyl-, -CO-Cι-4-Alkyl-, -CO-Alkylaryl- oder -CO-Allylrest,R 14 is hydrogen, a branched or unbranched, optionally substituted Cχ-C 4 alkyl, alkylaryl, -C0 2 -C 1 _ 4 alkyl, -C0 2 alkylaryl, -C0 2 allyl, -CO -Cι- 4 alkyl, -CO-alkylaryl or -CO-allyl radical,
R15 Wasserstoff, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cτ-C4-Alkylrest oder einen gegebenenfalls substituierten Aryl- oder Alkylarylrest .R 15 is hydrogen, a branched or unbranched, optionally substituted Cτ-C 4 alkyl radical or an optionally substituted aryl or alkylaryl radical.
R16, R17 unabhängig voneinander -NH2, Halogen oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl- oder Cι-C4-Alkoxyrest oder einen, gegebenfalls substituierten Arylrest,R 16 , R 17 independently of one another are -NH 2 , halogen or a branched or unbranched, optionally substituted C 1 -C 4 -alkyl or C 1 -C 4 alkoxy radical or an optionally substituted aryl radical,
Zi, z2< Z3 ' Z4 unabhängig voneinander CH, C-CH3, C-OCH3, C-Cl oder NZi , z 2 <Z 3 ' Z 4 independently of one another CH, C-CH 3 , C-OCH 3 , C-Cl or N
bedeuten, sowie die physiologisch verträglichen Salze, Prodrugs und die enantiomerenreinen oder diastereomeren- reinen und tautomeren Formen.mean, as well as the physiologically compatible salts, prodrugs and the enantiomerically pure or diastereomerically pure and tautomeric forms.
In Strukturelement L wird unter T eine Gruppe COOH oder ein zu COOH hydrolisierbarer Rest verstanden. Unter einem zu COOH hydrolisierbaren Rest wird ein Rest verstanden, der nach Hydrolyse in eine Gruppe COOH übergeht.In structural element L, T is understood to mean a group of COOH or a radical that can be hydrolyzed to COOH. A residue that can be hydrolyzed to COOH is understood to mean a residue which, after hydrolysis, changes into a COOH group.
Beispielhaft sei für einen zu COOH hydrolisierbaren Rest T die Gruppe OThe group O is an example of a radical T which can be hydrolyzed to COOH
II x II x
-C-R1 -CR 1
erwähnt, in der R1 die folgende Bedeutung hat:mentioned, in which R 1 has the following meaning:
a) OM, wobei M ein Metallkation, wie ein Alkalimetallkation, wie Lithium, Natrium, Kalium, das Äquivalent eines Erdalkalimetallkations, wie Calcium, Magnesium und Barium oder ein umweltverträgliches organisches Ammoniumion wie tertiäres Cι-C4-Alkylammonium oder Ammoniumion sein kann, wie beispielsweise ONa, OK oder OLi, b) ein verzweigter oder unverzweigter, gegebenenfalls mit Halogen substituierter Ci-Cs-Alkoxyrest, wie beispielsweise Methoxy, Ethoxy, Propoxy, 1-Methylethoxy, Butoxy, 1-Methyl- propoxy, 2-Methylpropoxy, 1, 1-Dimethylethoxy, insbesondere Methoxy, Ethoxy, 1-Methylethoxy, Pentoxy, Hexoxy, Heptoxy,a) OM, where M can be a metal cation, such as an alkali metal cation, such as lithium, sodium, potassium, the equivalent of an alkaline earth metal cation, such as calcium, magnesium and barium, or an environmentally compatible organic ammonium ion such as tertiary C 1 -C 4 -alkylammonium or ammonium ion, such as for example ONa, OK or OLi, b) a branched or unbranched, optionally halogen-substituted Ci-Cs alkoxy radical, such as methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy, 1, 1-dimethylethoxy, especially methoxy, Ethoxy, 1-methylethoxy, pentoxy, hexoxy, heptoxy,
Octoxy, Difluormethoxy, Trifluormethoxy, Chlordifluormethoxy, 1-Fluorethoxy, 2-Fluorethoxy, 2,2-Difluorethoxy, 1,1, 2, 2-Tetrafluorethoxy, 2 , 2 , 2-Trifluorethoxy, 2-Chlor-l, 1, 2-trifluorethoxy oder PentafluorethoxyOctoxy, difluoromethoxy, trifluoromethoxy, chlorodifluoromethoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 1,1, 2, 2-tetrafluoroethoxy, 2, 2, 2-trifluoroethoxy, 2-chloro-l, 1, 2- trifluoroethoxy or pentafluoroethoxy
c) ein verzweigter oder unverzweigter, gegebenenfalls mit Halogen substituierten Cι-C4-Alkylthiorest wie Methylthio, Ethylthio, Propylthio, 1-Methylethylthio, Butylthio, 1-Methylpropylthio, 2-Methylpropylthio oder 1, 1-Dimethyl- ethylthiorestc) a branched or unbranched, optionally substituted with halogen -CC 4 alkylthio radical such as methylthio, ethylthio, propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio or 1, 1-dimethylethylthio radical
d) ein gegebenenfalls substituierter -O-Alkylarylrest, wie beispielsweise -O-Benzyld) an optionally substituted -O-alkylaryl radical, such as -O-benzyl
e) R1 ferner ein Rest - (O)m-N(R18) (R19) , in dem m für 0 oder 1 steht und R18 und R19, die gleich oder unterschiedlich sein können, die folgende Bedeutung haben:e) R 1 is also a radical - (O) mN (R 18 ) (R 19 ), in which m represents 0 or 1 and R 18 and R 19 , which may be the same or different, have the following meaning:
Wasserstoff,Hydrogen,
Ci-Cg-Alkyl, wie beispielsweise Methyl, Ethyl, Propyl, 1-Methylethyl, Butyl, 1-Methylpropyl, 2-Methylpropyl, 1, 1-Dirnethylethyl, Pentyl, 1-Methylbutyl, 2-Methylbutyl, 1 , 2-Dimethylpropyl , 1 , 1-Dimethylpropyl , 2 , 2-Dimethylpropyl , 1-Ethylpropyl, Hexyl, 1-Methylpentyl, 1, 2-Dimethylbutyl,Ci-Cg-alkyl, such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1, 1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 1, 2-dimethylpropyl, 1, 1-dimethylpropyl, 2, 2-dimethylpropyl, 1-ethylpropyl, hexyl, 1-methylpentyl, 1, 2-dimethylbutyl,
1 , 3-Dimethylbutyl , 2 , 3-Dimethylbutyl , 1 , 1-Dirnethylbutyl ,1, 3-dimethylbutyl, 2, 3-dimethylbutyl, 1, 1-dimethylbutyl,
2, 2-Dimethylbutyl, 3 , 3-Dimethylbutyl, 1, 1,2-Trimethylpropyl, 1,2, 2-Trimethylpropyl, 1-Ethylbutyl , 2-Ethylbutyl , Heptyl oder Oktyl,2, 2-dimethylbutyl, 3, 3-dimethylbutyl, 1, 1,2-trimethylpropyl, 1,2, 2-trimethylpropyl, 1-ethylbutyl, 2-ethylbutyl, heptyl or octyl,
C3-C6~Alkenyl wie beispielsweise 2-Propenyl, 2-Butenyl, 3-Butenyl, l-Methyl-2-propenyl, 2-Methyl-2-propenyl, 2-Pentenyl, 3-Pentenyl, 4-Pentenyl, l-Methyl-2-butenyl, 2-Methyl-2-butenyl, 3-Methyl-2-butenyl, l-Methyl-3-butenyl, 2-Methyl-3-butenyl, 3-Methyl-3-butenyl, 1, l-Dimethyl-2- propenyl, l,2-Dimethyl-2-propenyl, l-Ethyl-2-propenyl, 2-Hexenyl, 3-Hexenyl, 4-Hexenyl, 5-Hexenyl, l-Methyl-2- pentenyl, 2-Methyl-2-pentenyl, 3-Methyl-2-pentenyl, 4-Methyl- 2-pentenyl, 3-Methy1-3-pentenyl, 4-Methyl-3-pentenyl, l-Methyl-4-pentenyl, 2-Methyl-4-pentenyl, 3-Methyl-4-entenyl, 4-Methyl-4-pentenyl, 1, l-Dimethyl-2-butenyl, 1, 1-Dimethyl- 3-butenyl, l,2-Dimethyl-2-butenyl, 1, 2-Dimethyl-3-butenyl, 1, 3-Dimethyl-2-butenyl, 1, 3-Dimethyl-3-butenyl, 2, 2-Dimethyl- 3-butenyl, 2, 3-Dimethyl-2-butenyl, 2, 3-Dimethyl-3-butenyl, l-Ethyl-2-butenyl, l-Ethyl-3-butenyl, 2-Ethyl-2-butenyl, 2-Ethyl-3-butenyl, 1, 1, 2-Trimethyl-2-propenyl, 1-Ethyl-l- methyl-2-propenyl und l-Ethyl-2-methyl-2-propenyl, insbesondere 2-Propenyl, 2-Butenyl, 3-Methyl-2-butenyl und 3-Methyl-2-pentenyl,C 3 -C 6 ~ alkenyl such as 2-propenyl, 2-butenyl, 3-butenyl, l-methyl-2-propenyl, 2-methyl-2-propenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, l -Methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, l-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1, l -Dimethyl-2-propenyl, l, 2-dimethyl-2-propenyl, l-ethyl-2-propenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, l-methyl-2-pentenyl, 2 -Methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 3-methyl-1-3-pentenyl, 4-methyl-3-pentenyl, l-methyl-4-pentenyl, 2-methyl -4-pentenyl, 3-methyl-4-entenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-2-butenyl , 1, 2-dimethyl-3-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, l-ethyl-2-butenyl, l-ethyl-3-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1, 1, 2-trimethyl-2-propenyl, 1-ethyl-l- methyl-2-propenyl and l-ethyl-2-methyl-2-propenyl, in particular 2-propenyl, 2-butenyl, 3-methyl-2-butenyl and 3-methyl-2-pentenyl,
C3-C6-Alkinyl wie beispielsweise 2-Propinyl, 2-Butinyl, 3-Butinyl, l-Methyl-2-propinyl, 2-Pentinyl, 3-Pentinyl,C 3 -C 6 alkynyl such as 2-propynyl, 2-butynyl, 3-butynyl, l-methyl-2-propynyl, 2-pentynyl, 3-pentynyl,
4-Pentinyl, 1-Methyl-3-butinyl, 2-Methyl-3-butinyl, 1-Methyl- 2-butinyl, 1, l-Dimethyl-2-propinyl, l-Ethyl-2-propinyl, 2-Hexinyl, 3-Hexinyl, 4-Hexinyl, 5-Hexinyl, 1-Methyl-2- pentinyl, l-Methyl-2-pentinyl, l-Methyl-3-pentinyl, 1-Methyl- 4-pentinyl, 2-Methyl-3-pentinyl, 2-Methyl-4-pentinyl,4-pentynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 1-methyl-2-butynyl, 1, l-dimethyl-2-propynyl, l-ethyl-2-propynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, l-methyl-2-pentynyl, l-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3- pentinyl, 2-methyl-4-pentinyl,
3-Methyl-4-pentinyl, 4-Methyl-2-pentinyl, 1, l-Dimethyl-2- butinyl, 1, l-Dimethyl-3-butinyl, 1, 2-Dimethyl-3-butinyl, 2, 2-Dimethyl-3-butinyl, l-Ethyl-2-butinyl, 1-Ethyl-3-butinyl, 2-Ethyl-3-butinyl und l-Ethyl-l-methyl-2-propinyl, vorzugs- weise 2-Propinyl, 2-Butinyl, l-Methyl-2-propinyl und l-Methyl-2-butinyl, insbesondere 2-Propinyl,3-methyl-4-pentynyl, 4-methyl-2-pentynyl, 1, l-dimethyl-2-butynyl, 1, l-dimethyl-3-butynyl, 1, 2-dimethyl-3-butynyl, 2, 2- Dimethyl-3-butynyl, l-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl and l-ethyl-l-methyl-2-propynyl, preferably 2-propynyl, 2 -Butinyl, l-methyl-2-propynyl and l-methyl-2-butynyl, especially 2-propynyl,
C3-C8-Cycloalkyl, wie beispielsweise Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl und Cycloheptyl, Cyclooctyl, wobei diese Alkyl-, Cycloalkyl-, Alkenyl- und Alkinylgruppen jeweils substituiert sein können,C 3 -C 8 cycloalkyl, such as, for example, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl and cycloheptyl, cyclooctyl, where these alkyl, cycloalkyl, alkenyl and alkynyl groups can each be substituted,
Phenyl, gegebenenfalls ein- oder mehrfach, z.B. ein- bis dreifach substituiert durch Halogen, Nitro, Cyano, Cι-C4-Alkyl, Cι-C4-Halogenalkyl, C1-C4-Alkoxy, Cι-C4-Halogen- alkoxy oder Cι-C4-Alkylthio wie beispielsweise 2-Fluorphenyl, 3-Chlorphenyl, 4-Bromphenyl, 2-Methylphenyl, 3-Nitrophenyl, 4-Cyanophenyl, 2-Trifluormethylphenyl, 3-Methoxyphenyl, 4-Trifluorethoxyphenyl, 2-Methylthiophenyl, 2,4-Dichlor- phenyl, 2-Methoxy-3-methylphenyl, 2 , 4-Dimethoxyphenyl, 2-Nitro-5-cyanophenyl, 2 , 6-DifluorphenylPhenyl, optionally mono- or polysubstituted, for example mono- to trisubstituted by halogen, nitro, cyano, C 4 -alkyl, C 4 haloalkyl, C 1 -C 4 -alkoxy, halo-C 4 alkoxy or -CC 4 alkylthio such as 2-fluorophenyl, 3-chlorophenyl, 4-bromophenyl, 2-methylphenyl, 3-nitrophenyl, 4-cyanophenyl, 2-trifluoromethylphenyl, 3-methoxyphenyl, 4-trifluoroethoxyphenyl, 2-methylthiophenyl, 2,4-dichlorophenyl, 2-methoxy-3-methylphenyl, 2, 4-dimethoxyphenyl, 2-nitro-5-cyanophenyl, 2, 6-difluorophenyl
oder R18 und R19 bilden gemeinsam eine zu einem Cyclus geschlossene, gegebenenfalls substituierte, z.B. durch Cι-C4-Alkyl substituierte C4-C7-Alkylenkette, die ein Hetero- atom, ausgewählt aus der Gruppe Sauerstoff, Schwefel oder Stickstoff, enthalten kann wie beispielsweise -(CH2)4-, -(CH2)5-, -(CH2)6-, -(CH2)7-, -(CH2)2-0-(CH2)2-, -CH2-S- (CH2) 3-, -(CH2)2-0-(CH2)3-, -NH-(CH2)3-, -CH2-NH- (CH2)2-, -CH2-CH=CH-CH2-, -CH=CH- (CH2) 3-, -CO- (CH2) 2-CO- oder -CO-(CH2)3-CO-. Bevorzugte Reste T sind -COOH, -CO-O-Ci-Cs-Alkyl oder -CO-O-or R 18 and R 19 together form a closed, optionally substituted, for example C 1 -C 4 -alkyl-substituted C 4 -C 7 -alkylene chain which is a hetero atom selected from the group consisting of oxygen, sulfur or nitrogen, May contain, for example, - (CH 2 ) 4 -, - (CH 2 ) 5 -, - (CH 2 ) 6 -, - (CH 2 ) 7 -, - (CH 2 ) 2 -0- (CH 2 ) 2 -, -CH 2 -S- (CH 2 ) 3 -, - (CH 2 ) 2 -0- (CH 2 ) 3 -, -NH- (CH 2 ) 3 -, -CH 2 -NH- (CH 2 ) 2 -, -CH 2 -CH = CH-CH 2 -, -CH = CH- (CH 2 ) 3 -, -CO- (CH 2 ) 2 -CO- or -CO- (CH 2 ) 3 -CO -. Preferred radicals T are -COOH, -CO-O-Ci-Cs-alkyl or -CO-O-
Benzyl .Benzyl.
Unter einem verzweigten oder unverzweigten Ci-Cß-Alkylrest wird unter R21 in Strukturelement L beispielsweise Methyl, Ethyl, Propyl, 1-Methylethyl, Butyl, 1-Methylpropyl, 2-Methylpropyl, 1, 1-Dimethylethyl, Pentyl, 1-Methylbutyl, 2-Methylbutyl, 1,2-Di- methylpropyl , 1 , 1-Dimethylpropyl , 2, 2-Dimethylpropyl, 1-Ethyl- propyl, Hexyl, 1-Methylpentyl, 1, 2-Dimethylbutyl, 1, 3-Dimethyl- butyl, 2, 3-Dimethylbutyl, 1, 1-Dimethylbutyl, 2 , 2-Dimethylbutyl, 3 , 3-Dimethylbutyl, 1,1, 2-Trimethylpropyl , 1,2, 2-Trimethylpropyl, 1-Ethylbutyl , 2-Ethylbutyl oder l-Ethyl-2-methylpropyl, bevorzugt Methyl, Ethyl, Propyl, Butyl oder i-Butyl verstanden.Under a branched or unbranched Ci-C ß- alkyl radical under R 21 in structural element L is, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1, 1-dimethylethyl, pentyl, 1-methylbutyl , 2-methylbutyl, 1,2-dimethylpropyl, 1, 1-dimethylpropyl, 2, 2-dimethylpropyl, 1-ethylpropyl, hexyl, 1-methylpentyl, 1, 2-dimethylbutyl, 1, 3-dimethylbutyl , 2, 3-dimethylbutyl, 1, 1-dimethylbutyl, 2, 2-dimethylbutyl, 3, 3-dimethylbutyl, 1,1, 2-trimethylpropyl, 1,2, 2-trimethylpropyl, 1-ethylbutyl, 2-ethylbutyl or l -Ethyl-2-methylpropyl, preferably methyl, ethyl, propyl, butyl or i-butyl understood.
Unter einem verzweigten oder unverzweigten C3-C6-Cycloalkylrest wird unter R21 in Strukturelement L beispielsweise Cyclopropyl, Cyclobutyl, Cyclopentyl oder Cyclohexyl verstandenA branched or unbranched C 3 -C 6 cycloalkyl radical is understood as R 21 in structural element L, for example cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl
Unter einem verzweigten oder unverzweigten Cι-C4-Alkyl-C3-C6- Cycloalkylrest wird unter R21 in Strukturelement L ein vorstehend erwähnter C3~C6-Cycloalkylrest verstanden, der an einen Cι-C4-Alkylrest substituiert ist.A branched or unbranched C 1 -C 4 alkyl-C 3 -C 6 cycloalkyl radical is understood under R 21 in structural element L to be a C 3 ~ C 6 cycloalkyl radical mentioned above which is substituted on a C 4 -C 4 alkyl radical.
Die Ci-Cε-Alkylreste, C3-Cg-Cycloalkylreste oder Cι-C4-Alkyl- C3-C6-Cycloalkylrest können mit bis zu 5 gleichen oder unterschiedlichen Resten, ausgewählt aus der Gruppe Halogen, Aryl oder Heteroaryl substituiert sein.The Ci-Cε-alkyl radicals, C 3 -Cg-cycloalkyl radicals or -C-C 4 alkyl- C 3 -C 6 cycloalkyl radicals can be substituted with up to 5 identical or different radicals selected from the group halogen, aryl or heteroaryl.
Unter einem C5-Cι2-Bicycloalkylrest werden für R21 beispielsweise Indanyl, Norbornyl oder Camphyl, unter einem Cδ-Cis-Tricycloalkyl- rest beispielsweise Adamantyl verstanden.A C 5 -C 2 bicycloalkyl radical for R 21 is understood to mean, for example, indanyl, norbornyl or camphyl, a C δ- cis tricycloalkyl radical, for example, adamantyl.
Unter einem mit bis zu drei gleichen oder verschiedenen Resten substituierten Aryl-, Alkylaryl-, Alkylheteroarylrest oder 3- bis 6 gliedrigen gesättigten, ungesättigten oder aromatischen Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann und zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Hetero- atome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann, werden für R21 in Strukturelement L beispielsweiseUnder an aryl, alkylaryl, alkylheteroaryl radical which is substituted by up to three identical or different radicals or a 3- to 6-membered saturated, unsaturated or aromatic heterocycle which can contain up to three different or identical heteroatoms 0, N, S and two radicals together a fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, can represent and the cycle optionally substituted or on this cycle another, optionally substituted, saturated, unsaturated or aromatic cycle can be fused, for R 21 in structural element L for example
Arylreste, wie beispielsweise Phenyl, 1-Naphthyl oder 2-Naphthyl, Alkylarylreste, wie beispielsweise Benzyl oder Homobenzyl,Aryl radicals, such as, for example, phenyl, 1-naphthyl or 2-naphthyl, Alkylaryl radicals, such as, for example, benzyl or homobenzyl,
Alkylheteroarylreste, wie beispielsweise -CH2-2-Pyridyl, -CH2-3-Pyridyl, -CH2-4-Pyridyl, -CH2-2-Thienyl, -CH2-3-Thienyl, -CH2-2-Thiazolyl, -CH2-4-Thiazolyl, CH2-5-Thiazolyl,Alkylheteroaryl radicals, such as, for example, -CH 2 -2-pyridyl, -CH 2 -3-pyridyl, -CH 2 -4-pyridyl, -CH 2 -2-thienyl, -CH 2 -3-thienyl, -CH 2 -2- Thiazolyl, -CH 2 -4-thiazolyl, CH 2 -5-thiazolyl,
-CH2-CH2-2-Pyridyl, -CH2-CH2-3-Pyridyl, -CH2-CH2-4-Pyridyl, -CH2-CH2-2-Thienyl, -CH2-CH2-3-Thienyl, -CH2-CH2-2-Thiazolyl, -CH2-CH2-4-Thiazolyl, oder -CH2-CH2-5-Thiazolyl, vorzugsweise -CH2-2-Pyridyl, -CH2-2-Thienyl, oder -CH2-2-Thiazolyl oder-CH 2 -CH 2 -2-pyridyl, -CH 2 -CH 2 -3-pyridyl, -CH 2 -CH 2 -4-pyridyl, -CH 2 -CH 2 -2-thienyl, -CH 2 -CH 2 -3-thienyl, -CH 2 -CH 2 -2-thiazolyl, -CH 2 -CH 2 -4-thiazolyl, or -CH 2 -CH 2 -5-thiazolyl, preferably -CH 2 -2-pyridyl, -CH 2 -2-thienyl, or -CH 2 -2-thiazolyl or
Heteroarylreste, wie beispielsweise 2-Pyridyl, 3-Pyridyl, 4-Pyridyl, 2-Furyl, 3-Furyl, 2-Pyrrolyl, 3-Pyrrolyl, 2-Thienyl, 3-Thienyl, 2-Thiazolyl, 4-Thiazolyl, 5-Thiazolyl, 2-Oxazolyl, 4-Oxazolyl, 5-Oxazolyl, 2-Pyrimidyl, 4-Pyrimidyl, 5-Pyrimidyl, 6-Pyrimidyl, 3-Pyrazolyl, 4-Pyrazolyl, 5-Pyrazolyl, 3-Iso- thiazolyl, 4-Isothiazolyl, 5-Isothiazolyl, 2-lmidazolyl, 4-Imidazolyl, 5-Imidazolyl, 3-Pyridazinyl, 4-Pyridazinyl, 5-Pyridazinyl oder 6-Pyridazinyl, vorzugsweise 2-Pyridyl, 3-Pyridyl, 4-Pyridyl, 2-Furyl, 3-Furyl, 2-Thienyl, 3-Thienyl, 2-Thiazolyl, 4-Thiazolyl oder 5-Thiazolyl verstanden,Heteroaryl radicals, such as, for example, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl, 3-furyl, 2-pyrrolyl, 3-pyrrolyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl, 5- Thiazolyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-pyrimidyl, 4-pyrimidyl, 5-pyrimidyl, 6-pyrimidyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 3-isothiazolyl, 4- Isothiazolyl, 5-isothiazolyl, 2-imidazolyl, 4-imidazolyl, 5-imidazolyl, 3-pyridazinyl, 4-pyridazinyl, 5-pyridazinyl or 6-pyridazinyl, preferably 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl , 3-furyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl or 5-thiazolyl understood,
wobei die Arylreste, Alkylarylreste, Alkylheteroarylreste und Heteroarylreste mit bis zu drei gleichen oder verschiedenen Resten, beispielsweise ausgewählt aus der nachfolgenden Gruppe substituiert sein können:where the aryl radicals, alkylaryl radicals, alkylheteroaryl radicals and heteroaryl radicals can be substituted with up to three identical or different radicals, for example selected from the following group:
-N02, -NH2 -OH, -CN, -COOH, -C00-Cx-C4-Alkyl, Halogen, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl- , C3-C6-Cycloalkyl-, Cι~C4-Alkoxy-, Cι-C4-Thioalkyl-, -0-CH2-COO-Cι-C-Alkyl, -NH-CO-Cι-C-Alkyl, -CO-NH-Cι-C4~Alkyl, -NH-S02-Cι-C-Alkyl, -S02-NH-Cι-C-Alkyl, -N(Cι-C4-Alkyl)2, - NH-Cι-C4-Alkyl-, oder -S02-Cχ-C4-Alkylrest, einen gegebenfalls substituierten -NH-CO-Phenyl, -CO-NH-Phenyl, -NH-S02-Phenyl, -S02-NH-Phenyl, -NH-CO-Benzyl , -CO-NH-Benzyl , -NH-S02-Benzyl, -S02-NH-Benzyl, einen gegebenfalls substituierten Rest -S02-NT1T2 oder -CO-NT-T2 wobei die beiden Reste T1 und T2 ein cyclisches Amin bilden können, oder einen 3 bis 6 gliedrigen, gegebenenfalls substituierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome O, N, S enthalten kann, oder zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann darstellen und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter Cyclus ankondensiert sein kann. Bevorzugte Substituenten der Arylreste, Alkylarylreste, Alkylheteroarylreste und Heteroarylreste für R21 sind Cι-C4~Alkyl, C3-C6-Cycloalkyl, -COOH, -COOMe, -CF3, -CN, Cι-C4-Alkoxy-, -SCH3, -0-CH2-COOH, Phenyl, -S02CH3, -N02, -OH, -NH2, -N-Pyrrolidinyl, -N-Piperidinyl , -N-Morpholinyl, -N-Piperazinyl, -NH-Cι-C4-Alkyl, -N(Cι-C-Alkyl)2, F, Cl, Br oder I.-N0 2, -NH 2 -OH, -CN, -COOH, -C00-C x -C 4 alkyl, halogen, a branched or unbranched, optionally substituted C 1 -C 4 alkyl, C 3 -C 6 - Cycloalkyl, -C ~ C 4 alkoxy, -C -C 4 thioalkyl, -0-CH 2 -COO-Cι-C-alkyl, -NH-CO-Cι-C-alkyl, -CO-NH-Cι -C 4 ~ alkyl, -NH-S0 2 -Cι-C-alkyl, -S0 2 -NH-Cι-C-alkyl, -N (Cι-C 4 alkyl) 2 , - NH-Cι-C 4 - Alkyl, or -S0 2 -Cχ-C 4 alkyl, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-S0 2 -phenyl, -S0 2 -NH-phenyl, -NH -CO-benzyl, -CO-NH-benzyl, -NH-S0 2 -benzyl, -S0 2 -NH-benzyl, an optionally substituted radical -S0 2 -NT 1 T 2 or -CO-NT-T 2 wherein the both radicals T 1 and T 2 can form a cyclic amine, or a 3 to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms O, N, S, or two Leftovers together a fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S and the cycle can be optionally substituted or a further, optionally substituted cycle can be fused onto this cycle. Preferred substituents of the aryl radicals, alkylaryl radicals, Alkylheteroarylreste and heteroaryl for R 21 are Cι-C4 ~ alkyl, C 3 -C 6 cycloalkyl, -COOH, -COOMe, -CF3, -CN, Cι-C 4 alkoxy, -SCH 3 , -0-CH 2 -COOH, phenyl, -S0 2 CH 3 , -N0 2 , -OH, -NH 2 , -N-pyrrolidinyl, -N-piperidinyl, -N-morpholinyl, -N-piperazinyl , -NH-Cι-C4 alkyl, -N (Cι-C alkyl) 2, F, Cl, Br or I.
Bevorzugte Substituenten der Arylreste, Alkylarylreste, Alkylheteroarylreste und Heteroarylreste für R21, bei denen zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann darstellen und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter Cyclus ankondensiert sein kann, sind folgende, zweifach gebundene Strukturelemente:Preferred substituents of the aryl radicals, alkylaryl radicals, alkylheteroaryl radicals and heteroaryl radicals for R 21 , in which two radicals together represent an fused, saturated, unsaturated or aromatic carbocycle or heterocycle which can contain up to three different or identical heteroatoms 0, N, S and the cycle optionally substituted or a further, optionally substituted cycle may be fused onto this cycle are the following, double-bonded structural elements:
Unter einem verzweigten oder unverzweigten Ci-Cs-Alkylrest werden für R22 im Strukturelement L beispielsweise die vorstehend für R21 erwähnten Ci-Cß-Alkylreste vorzugsweise 1, 1-Dimethylethyl verstanden.A branched or unbranched Ci-Cs-alkyl radical for R 22 in the structural element L means, for example, the Ci-C β -alkyl radicals mentioned above for R 21 , preferably 1, 1-dimethylethyl.
Arylreste für R22 im Strukturelement L sind beispielsweise Phenyl, 1-Naphthyl oder 2-Naphthyl, vorzugsweise Phenyl; Alkylarylreste für R22 im Strukturelement L sind vorzugsweise Benzyl oder Homo- benzyl .Aryl radicals for R 22 in structural element L are, for example, phenyl, 1-naphthyl or 2-naphthyl, preferably phenyl; Alkylaryl radicals for R 22 in the structural element L are preferably benzyl or homobenzyl.
Als Substituenten der Ci-Cδ-Alkylrest, Arylreste oder Alkylarylreste für R22 im Strukturelement L kommen die vorstehend für die Arylreste, Alkylarylreste, Alkylheteroarylreste und Heteroarylreste von R21 erwähnten Substituenten in Frage.As substituents of the Ci-C δ -alkyl radical, aryl radicals or alkylaryl radicals for R 22 in the structural element L described above for the aryl radicals, alkylaryl radicals, Alkylheteroarylreste and heteroaryl of R 21 come mentioned substituents in question.
Bei Rest R3 im Strukturelement L kann der Index b 0, 1, 2 oder 3, vorzugsweise 0, 1, oder 2 und der Index c 0 oder 1 bedeuten. Der Rest X stellt einen zweifach gebundenen Rest ausgewählt aus der Gruppe -S02-, -S-, -0-, -CO-, -NH-S02-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R31)-, -N(R31)-CO-, -S02-NH-, -S02-N(R31)- oder -N(R31)-S0- dar. Im Fall von zweifach mit R31 substituierten Resten können die die beiden Reste R31 gleich oder verschieden sein.In the case of radical R 3 in the structural element L, the index b can be 0, 1, 2 or 3, preferably 0, 1 or 2 and the index c can be 0 or 1. The radical X represents a double bonded radical selected from the group -S0 2 -, -S-, -0-, -CO-, -NH-S0 2 -, -O-CO-, -CO-O-, -NH -CO-, -CO-NH-, -CO-N (R 31 ) -, -N (R 31 ) -CO-, -S0 2 -NH-, -S0 2 -N (R 31 ) - or -N (R 31 ) -S0-. In the case of doubly substituted with R 31 The two R 31 radicals can be the same or different.
Unter einem verzweigten oder unverzweigten Ci-Cg-Alkylrest wird unter R31 in Strukturelement L beispielsweise Methyl, Ethyl, Propyl, 1-Methylethyl, Butyl, 1-Methylpropyl, 2-Methylpropyl, 1, 1-Dimethylethyl, Pentyl, 1-Methylbutyl, 2-Methylbutyl , 1,2-Di- methylpropyl , 1, 1-Dimethylpropyl, 2, 2-Dimethylpropyl, 1-Ethyl- propyl, Hexyl, 1-Methylpentyl, 1, 2-Dimethylbutyl, 1, 3-Dimethyl- butyl, 2, 3-Dimethylbutyl, 1, 1-Dimethylbutyl, 2 , 2-Dimethylbutyl, 3, 3-Dimethylbutyl, 1, 1, 2-Trimethylpropyl, 1,2, 2-Trimethylpropyl, 1-Ethylbutyl , 2-Ethylbutyl oder l-Ethyl-2-methylpropyl, bevorzugt Methyl, Ethyl, Propyl, Butyl, iso-Propyl, sec-Butyl und tert- Butyl verstanden.Under a branched or unbranched C 1 -C 6 -alkyl radical, R 31 in structural element L is, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1, 1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 1,2-dimethylpropyl, 1, 1-dimethylpropyl, 2, 2-dimethylpropyl, 1-ethylpropyl, hexyl, 1-methylpentyl, 1, 2-dimethylbutyl, 1, 3-dimethylbutyl, 2, 3-dimethylbutyl, 1, 1-dimethylbutyl, 2, 2-dimethylbutyl, 3, 3-dimethylbutyl, 1, 1, 2-trimethylpropyl, 1,2, 2-trimethylpropyl, 1-ethylbutyl, 2-ethylbutyl or 1- Ethyl-2-methylpropyl, preferably methyl, ethyl, propyl, butyl, isopropyl, sec-butyl and tert-butyl understood.
Unter einem verzweigten oder unverzweigten Cι-C4-Alkoxyrest wird unter R31 in Strukturelement L beispielsweise Methoxy, Ethoxy, Propoxy, 1-Methylethoxy, Butoxy, 1-Methylpropoxy, 2-Methylpropoxy oder 1, 1-Dimethylethoxy, insbesondere Methoxy, Ethoxy oder 1-Methylethoxy verstanden.Under a branched or unbranched C 1 -C 4 alkoxy radical, R 31 in structural element L is, for example, methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy or 1, 1-dimethylethoxy, in particular methoxy, ethoxy or 1-methylethoxy understood.
-O-Alkylaryl- oder -O-Arylreste sind beispielsweise -O-Phenyl, -O-1-Naphthyl, -0-2-Naphthyl oder -O-Benzyl.-O-alkylaryl or -O-aryl radicals are, for example, -O-phenyl, -O-1-naphthyl, -0-2-naphthyl or -O-benzyl.
Die Ci-Cß-Alkyl-, Cι-C4-Alkoxyreste von R31 in Strukturelement L können mit bis zu fünf gleichen oder unterschiedlichen Resten, ausgewählt aus der Gruppe Halogen, Aryl oder Heteroaryl substituiert sein.The Ci-C ß- alkyl, -CC 4 alkoxy radicals of R 31 in structural element L can be substituted with up to five identical or different radicals selected from the group halogen, aryl or heteroaryl.
Unter substituierten -O-Alkylaryl- oder -O-Arylresten werden beispielsweise die vorstehend erwähnten -O-Alkylaryl- oder -O-Arylreste verstanden, wobei der Arylteil mit bis zu drei gleichen oder verschiedenen Resten ausgewählt aus der folgenden Gruppe substituiert sein kann:Substituted -O-alkylaryl or -O-aryl radicals are understood to mean, for example, the aforementioned -O-alkylaryl or -O-aryl radicals, it being possible for the aryl part to be substituted with up to three identical or different radicals selected from the following group:
-N02, -NH2, -OH, -CN, -COOH, -COO-Cι-C-Alkyl, Halogen, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-, C3-C6-Cycloalkyl-, Cι-C-Alkoxy-, Cι-C4-Thioalkyl-, -0-CH2-COO-Cι-C4-Alkyl, -NH-CO-Cι-C4-Alkyl, -CO-NH-Cι-C-Alkyl, -NH-S02-Cι-C4-Alkyl, -S0-NH-Cι-C4-Alkyl, -N(Cι-C-Alkyl)2, - NH-Cι-C4-Alkyl-, oder -S02-Cι-C4-Alkylrest, einen gegebenfalls substituierten -NH-CO-Phenyl, -CO-NH-Phenyl, -NH-S02-Phenyl, -S02-NH-Phenyl, -NH-CO-Benzyl, -CO-NH-Benzyl, -NH-S02-Benzyl, -S02-NH-Benzyl, einen gegebenfalls substituierten Rest -S02-NT1T2 oder -CO-NT^-T2 wobei die beiden Reste T1 und T2 ein cyclisches Amin bilden können, oder einen 3 bis 6 gliedrigen, gegebenenfalls substituierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, oder zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann darstellen und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter Cyclus ankondensiert sein kann.-N0 2 , -NH 2 , -OH, -CN, -COOH, -COO-Cι-C-alkyl, halogen, a branched or unbranched, optionally substituted Cι-C 4 alkyl, C 3 -C 6 cycloalkyl - C 1 -C 4 -alkoxy, C 1 -C 4 thioalkyl, -0-CH 2 -COO-C 1 -C 4 -alkyl, -NH-CO-C 1 -C 4 -alkyl, -CO-NH-Cι -C-Alkyl, -NH-S0 2 -Cι-C 4 -alkyl, -S0-NH-Cι-C 4 -alkyl, -N (-C-C-alkyl) 2 , - NH-Cι-C 4 alkyl -, or -S0 2 -C-C 4 alkyl, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-S0 2 -phenyl, -S0 2 -NH-phenyl, -NH- CO-benzyl, -CO-NH-benzyl, -NH-S0 2 -benzyl, -S0 2 -NH-benzyl, an optionally substituted radical -S0 2 -NT 1 T 2 or -CO-NT ^ -T 2 wherein the both radicals T 1 and T 2 can form a cyclic amine, or a 3 to 6-membered, optionally substituted, saturated, unsaturated or aromatic Carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, or two radicals together form a fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which contain up to three different or identical heteroatoms 0, N, S can represent and the cycle optionally substituted or a further, optionally substituted cycle can be fused onto this cycle.
Unter einem primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest wird unter R31 in Strukturelement L ein primärer Aminorest -NH , ein sekundärer Aminorest -NH(R311) oder ein tertiärer Aminorest -N(R311) (R312) verstanden, wobeiA primary or optionally secondary or tertiary substituted amino radical is understood under R 31 in structural element L to mean a primary amino radical -NH, a secondary amino radical -NH (R 311 ) or a tertiary amino radical -N (R 311 ) (R 312 ), where
R311 und R312 unabhängig voneinander Cχ-C4-Alkyl oder C3-Cδ-Cydo- alkyl, wie vorstehend erwähnt, gegebenenfalls substituiertes Aryl, vorzugsweise Phenyl, Alkylaryl, vorzugsweise Benzyl, -CO-Cι-C4-Alkyl, vorzugsweise -C0-CH3 oder -CO-Aryl, vorzugsweise -CO-Phenyl sein können.R 311 and R 312 independently of one another are Cχ-C 4 -alkyl or C 3 -C δ- Cydoalkyl, as mentioned above, optionally substituted aryl, preferably phenyl, alkylaryl, preferably benzyl, -CO-Cι-C 4 alkyl, can preferably be -C0-CH 3 or -CO-aryl, preferably -CO-phenyl.
Für den Fall c = 1 und X = CO ergeben sich die entsprechenden Amidreste.For the case c = 1 and X = CO, the corresponding amide residues result.
Cyclische tertiäre Amid- oder Aminoreste ergeben sich für den Fall, daß R31 einen der nachstehend beschriebenen Heterocyclen darstellt der über den Ringstickstoff an X = CO bzw. direkt gebunden ist. Bevorzugte Amidreste -X-R31 sind beispielsweiseCyclic tertiary amide or amino radicals result when R 31 is one of the heterocycles described below which is bonded to X = CO or directly via the ring nitrogen. Preferred amide residues -XR 31 are for example
Unter einem gegebenenfalls mit Cι~C4-Alkyl oder Aryl substituier- ten C2-Cg-Alkinyl- oder C2-C6-Alkenylrest, werden unter R31 in Strukturelement L beispielsweise C-C6-Alkinylreste, wie beispielsweise Ethinyl, 2-Propinyl, 2-Butinyl, 3-Butinyl, 1-Methyl- 2-propinyl, 2-Pentinyl, 3-Pentinyl, 4-Pentinyl, l-Methyl-3- butinyl, 2-Methy1-3-butinyl, l-Methyl-2-butinyl, 1, l-Dimethyl-2- propinyl, l-Ethyl-2-propinyl, 2-Hexinyl, 3-Hexinyl, 4-Hexinyl, 5-Hexinyl, 1-Methy1-2-pentinyl, l-Methyl-2-pentinyl, l-Methyl-3- pentinyl, l-Methyl-4-pentinyl, 2-Methyl-3-pentinyl, 2-Methyl-4- pentinyl, 3-Methyl-4-pentinyl, 4-Methyl-2-pentinyl, 1 , 1-Dimethyl- 2-butinyl, 1, 1-Dirnethy1-3-butinyl, 1, 2-Dirne hy1-3-butinyl, 2, 2-Dirnethy1-3-butinyl, l-Ethyl-2-butinyl, l-Ethyl-3-butinyl, 2-Ethyl-3-butinyl oder l-Ethyl-l-methyl-2-propinyl, vorzugsweise 2-Propinyl oder Ethinyl oder C2-C6-Alkenylrest, wie beispielsweise Vinyl, 2-Propenyl, 2-Butenyl, 3-Butenyl, l-Methyl-2-propenyl, 2-Methyl-2-propenyl, 2-Pentenyl, 3-Pentenyl, 4-Pentenyl, l-Methyl-2-butenyl, 2-Methyl- 2-butenyl, 3-Methyl-2-butenyl, l-Methyl-3-butenyl, 2-Methyl-3- butenyl, 3-Methy1-3-butenyl, 1, l-Dimethyl-2-propenyl, 1,2-Di- methyl-2-propenyl, l-Ethyl-2-propenyl, 2-Hexenyl, 3-Hexenyl, 4-Hexenyl, 5-Hexenyl, l-Methyl-2-pentenyl, 2-Methyl-2-pentenyl, 3-Methy1-2-pentenyl, 4-Methyl-2-pentenyl, 3-Methyl-3-pentenyl, 4-Methyl-3-pentenyl, l-Methyl-4-pentenyl, 2-Methyl-4-pentenyl, 3-Methyl-4-pentenyl, 4-Methyl-4-pentenyl, 1, l-Dimethyl-2-butenyl, 1, l-Dimethyl-3-butenyl, 1, 2-Dimethyl-2-butenyl, 1, 2-Dimethyl-3- butenyl, 1, 3-Dimethy1-2-butenyl, 1, 3-Dimethyl-3-butenyl, 2,2-Di- methyl-3-butenyl , 2 , 3-Dimethyl-2-butenyl, 2 , 3-Dimethyl-3-butenyl, l-Ethyl-2-butenyl, 1-Ethyl-3-butenyl, 2-Ethyl-2-butenyl, 2-Ethyl- 3-butenyl, 1, 1, 2-Trimethyl-2-propenyl, l-Ethyl-l-methyl-2- propenyl oder 1-Ethyl-2-methy1-2-propenyl, insbesondere 2-Propenyl oder VinylUnder a substitutability th optionally substituted by Cι ~ C 4 alkyl or aryl C 2 -CG-alkynyl or C 2 -C 6 alkenyl are from R 31 in structural element L, for example, CC 6 -alkynyl, such as ethynyl, 2- Propynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, l-methyl-3-butynyl, 2-methyl-1-3-butynyl, l-methyl- 2-butynyl, 1, l-dimethyl-2-propynyl, l-ethyl-2-propynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-1-2-pentynyl, l-methyl- 2-pentynyl, l-methyl-3-pentynyl, l-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-4-pentynyl, 4-methyl-2- pentinyl, 1, 1-dimethyl-2-butinyl, 1, 1-dirnethy1-3-butinyl, 1, 2-dirne hy1-3-butinyl, 2, 2-dirnethy1-3-butinyl, l-ethyl-2-butinyl , l-ethyl-3-butynyl, 2-ethyl-3-butynyl or l-ethyl-l-methyl-2-propynyl, preferably 2-propynyl or ethynyl or C 2 -C 6 alkenyl, such as vinyl, 2-propenyl, 2-butenyl, 3-butenyl, l-methyl-2-propenyl, 2-methyl-2-propenyl, 2-pentenyl, 3-pentenyl, 4 -Pentenyl, l-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, l-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl1-3-butenyl , 1, l-dimethyl-2-propenyl, 1,2-dimethyl-2-propenyl, l-ethyl-2-propenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, l-methyl -2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-1-2-pentenyl, 4-methyl-2-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, l-methyl-4 -pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1, l-dimethyl-2-butenyl, 1, l-dimethyl-3-butenyl, 1, 2 -Dimethyl-2-butenyl, 1, 2-dimethyl-3-butenyl, 1, 3-dimethy1-2-butenyl, 1, 3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2 , 3-dimethyl-2-butenyl, 2, 3-dimethyl-3-butenyl, l-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl , 1, 1, 2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl or 1-ethyl-2-meth y1-2-propenyl, especially 2-propenyl or vinyl
verstanden, die mit gegebenenfalls substituierten Cι-C4-Alkyl- resten, oder Arylresten wie vorstehend erwähnt, vorzugsweiseunderstood, with optionally substituted -CC 4 alkyl radicals, or aryl radicals as mentioned above, preferably
Phenyl, substituiert sein können, wie vorzugsweise Phenylethinyl oder Phenylethenyl .Phenyl, such as preferably phenylethynyl or phenylethenyl.
Unter einem C5-Cχ2-Bicycloalkylrest werden für R31 beispielsweise Indanyl, Norbornyl oder Camphyl, unter einem Cß-Cis-Tricycloalkyl- rest beispielsweise Adamantyl verstanden.A C 5 -Cχ 2 bicycloalkyl radical for R 31 means, for example, indanyl, norbornyl or camphyl, and a C ß- cis tricycloalkyl radical, for example, adamantyl.
Unter einem mit bis zu drei gleichen oder verschiedenen Resten substituierten, 3-6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, C3-C8~Cycloalkyl-, Aryl- oder Heteroarylrest, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Hetero- atome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann, werden für R31 in Strukturelement L beispielsweiseUnder a substituted with up to three identical or different radicals, 3-6 membered, saturated or unsaturated heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, C 3 -C 8 ~ cycloalkyl, aryl or Heteroaryl radical, where two radicals together can represent a fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical hetero atoms 0, N, S, and the cycle optionally substituted or a further one on this cycle, optionally substituted, saturated, unsaturated or aromatic cycle can be fused, for R 31 in structural element L for example
3- bis 6 gliedrige, gesättigte oder ungesättigten Heterocyclen, die bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten können wie N-Pyrrolidinyl, N-Piperidinyl, N-Hexahydro- azepinyl, N-Morpholinyl oder N-Piperazinyl, wobei bei Hetero- cyclen die freie Aminprotonen tragen, wie beispielsweise3- to 6-membered, saturated or unsaturated heterocycles which can contain up to three different or identical heteroatoms 0, N, S, such as N-pyrrolidinyl, N-piperidinyl, N-hexahydro-azepinyl, N-morpholinyl or N-piperazinyl, where in the case of heterocycles which carry free amine protons, for example
N-Piperazinyl die freien Aminprotonen durch gängige Aminschutz- gruppen, wie beispielsweise Methyl, Benzyl, Boc (ter . -Butoxy- carbonyl), Z (Benzyloxycarbonyl) , Tosyl, -S02-Cι-C4-Alkyl, -S0 -Phenyl oder -S02-Benzyl ersetzt sein können,N-piperazinyl the free amine protons by common amine protecting groups, such as methyl, benzyl, Boc (ter. -Butoxy- carbonyl), Z (benzyloxycarbonyl), tosyl, -S0 2 -Cι-C 4 alkyl, -S0 -phenyl or -S0 2 -benzyl can be replaced,
C3-C8-Cycloalkylreste, wie vorstehend für R21 beschrieben,C 3 -C 8 cycloalkyl radicals as described above for R 21 ,
Arylreste, wie beispielsweise Phenyl, 1-Naphthyl oder 2-Naphthyl oderAryl radicals, such as, for example, phenyl, 1-naphthyl or 2-naphthyl or
Heteroarylreste, wie beispielsweise 2-Pyridyl, 3-Pyridyl, 4-Pyridyl, 2-Furyl, 3-Furyl, 2-Pyrrolyl, 3-Pyrrolyl, 2-Thienyl, 3-Thienyl, 2-Thiazolyl, 4-Thiazolyl, 5-Thiazolyl, 2-Oxazolyl, 4-0xazolyl, 5-Oxazolyl, 2-Pyrimidyl, 4-Pyrimidyl, 5-Pyrimidyl, 6-Pyrimidyl, 3-Pyrazolyl, 4-Pyrazolyl, 5-Pyrazolyl, 3-Iso- thiazolyl, 4-Isothiazolyl, 5-Isothiazolyl, 2-Imidazolyl, 4-Imidazolyl, 5-Imidazolyl, 3-Pyridazinyl, 4-Pyridazinyl, 5-Pyridazinyl oder 6-Pyridazinyl, vorzugsweise 2-Pyridyl, 3-Pyridyl, 4-Pyridyl, 2-Furyl, 3-Furyl, 2-Thienyl, 3-Thienyl, 2-Thiazolyl, 4-Thiazolyl oder 5-Thiazolyl verstanden,Heteroaryl radicals, such as, for example, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl, 3-furyl, 2-pyrrolyl, 3-pyrrolyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl, 5- Thiazolyl, 2-oxazolyl, 4-0xazolyl, 5-oxazolyl, 2-pyrimidyl, 4-pyrimidyl, 5-pyrimidyl, 6-pyrimidyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 3-isothiazolyl, 4- Isothiazolyl, 5-isothiazolyl, 2-imidazolyl, 4-imidazolyl, 5-imidazolyl, 3-pyridazinyl, 4-pyridazinyl, 5-pyridazinyl or 6-pyridazinyl, preferably 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl , 3-furyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl or 5-thiazolyl understood,
wobei die Heterocyclen-, C3-Cs-Cycloalkyl-, Aryl- und Heteroarylreste gegebenenfalls mit bis zu drei gleichen oder verschiedenen Resten, beispielsweise ausgewählt aus der nachfolgenden Gruppe, substituiert sein können:where the heterocycles, C 3 -Cs cycloalkyl, aryl and heteroaryl radicals can optionally be substituted with up to three identical or different radicals, for example selected from the following group:
-N02, -NH2/ -OH, -CN, -COOH, -COO-Cι-C-Alkyl, Halogen, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-, C3-C6-Cycloalkyl-, Cι-C4-Alkoxy-, Cι-C-Thioalkyl-, -0-CH2-COO-Cι-C4-Alkyl, -NH-CO-Cι-C4-Alkyl, -CO-NH-Cι-C4-Alkyl, -NH-S02-Cι-C4-Alkyl, -S02-NH-Cι-C-Alkyl, -N(Cι-C4-Alkyl) 2, -NH-Cι-C4-Alkyl-, oder -S02-Cι_4-Alkylrest, einen gegebenfalls substituierten -NH-CO-Phenyl, -CO-NH-Phenyl, -NH-S02-Phenyl, -S02-NH-Phenyl, -NH-CO-Benzyl , -CO-NH-Benzyl, -NH-S02-Benzyl, -S02-NH-Benzyl, einen gegebenfalls substituierten Rest -S0-NT1T2 oder -CO-NTiT2, wobei die beiden Reste T1 und T2 ein cyclisches Amin bilden können, oder einen 3 bis 6 gliedrigen, gegebenenfalls substituierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, oder zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann darstellen und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter Cyclus ankondensiert sein kann. Bevorzugte Substituenten der Heterocyclen-, C3-C8-Cycloalkyl-, Aryl- und Heteroarylreste für R31 sind Cι-C4-Alkyl-, -COOH, -COOMe, -CF3, -CN, Cι-C -Alkoxy-, -SCH3, -O-CH2-C0OH, -Phenyl, -S02CH3, -N02, -OH, -NH2, -N-Pyrrolidinyl-, -N-Piperidinyl, -N-Morpholinyl, -N-Piperazinyl, -NH-Cι-C4-Alkyl , -N(Cι-C4-Alkyl)2, F, Cl, Br oder I.-N0 2 , -NH 2 / -OH, -CN, -COOH, -COO-Cι-C-alkyl, halogen, a branched or unbranched, optionally substituted Cι-C 4 alkyl, C 3 -C 6 cycloalkyl - C 1 -C 4 alkoxy, C 1 -C thioalkyl, -0-CH 2 -COO-C 1 -C 4 alkyl, -NH-CO-C 1 -C 4 -alkyl, -CO-NH-Cι -C 4 alkyl, -NH-S0 2 -Cι-C 4 alkyl, -S0 2 -NH-Cι-C-alkyl, -N (-Cι-C 4 alkyl) 2 , -NH-Cι-C 4 -Alkyl-, or -S0 2 -Cι_ 4 -alkyl radical, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-S0 2 -phenyl, -S0 2 -NH-phenyl, -NH- CO-benzyl, -CO-NH-benzyl, -NH-S0 2 -benzyl, -S0 2 -NH-benzyl, an optionally substituted radical -S0-NT 1 T 2 or -CO-NT i T 2 , the two Residues T 1 and T 2 can form a cyclic amine, or a 3 to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, or two residues together a fused, saturated, unsaturated n or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S and the cycle can be optionally substituted or a further, optionally substituted cycle can be fused onto this cycle. Preferred substituents of the heterocycles, C 3 -C 8 cycloalkyl, aryl and heteroaryl radicals for R 31 are C 1 -C 4 -alkyl, -COOH, -COOMe, -CF 3 , -CN, C 1 -C 8 -alkoxy- , -SCH 3 , -O-CH 2 -C0OH, -phenyl, -S0 2 CH 3 , -N0 2 , -OH, -NH 2 , -N-pyrrolidinyl-, -N-piperidinyl, -N-morpholinyl, - N-piperazinyl, -NH--C-C 4 alkyl, -N (-C-C 4 alkyl) 2 , F, Cl, Br or I.
Bevorzugte Substituenten der Heterocyclen-, C3-C8-Cycloalkyl-, Aryl- und Heteroarylreste für R31, bei denen zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann darstellen und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter Cyclus ankondensiert sein kann, sind folgende, zweifach gebundene Strukturelemente:Preferred substituents of the heterocycles, C 3 -C 8 -cycloalkyl, aryl and heteroaryl radicals for R 31 , in which two radicals together form an fused, saturated, unsaturated or aromatic carbocycle or heterocycle which has up to three different or identical heteroatoms 0, N, S can contain and the cycle can be optionally substituted or a further, optionally substituted cycle can be fused onto this cycle, the following double-bonded structural elements are:
Beispiele für die sich ergebenden kondensierten CyclusSysteme für R31 sind beispielsweise die entsprechenden Dioxolanyle, Benzopyrrolyle, Benzofuryle, Benzothienyle oder Fluorenyle.Examples of the resulting condensed cycle systems for R 31 are, for example, the corresponding dioxolanyls, benzopyrrolyls, benzofuryls, benzothienyls or fluorenyls.
Unter einem verzweigten oder unverzweigten, gegebenenfalls substituierten Cι~C4-Alkylrest werden für R4 in Strukturelement L beispielsweise Methyl, Ethyl, Propyl, i-Propyl, Butyl, t-Butyl oder i-Butyl, vorzugsweise Methyl verstanden.A branched or unbranched, optionally substituted C 1 -C 4 -alkyl radical for R 4 in structural element L is understood to mean, for example, methyl, ethyl, propyl, i-propyl, butyl, t-butyl or i-butyl, preferably methyl.
Unter einem verzweigten oder unverzweigten, gegebenenfalls substituierten C3-C6-Cycloalkylrest werden für R4 in Strukturelement L die vorstehend für R21 erwähnten, gegebenfalls mit bis zu 5 Resten wie Halogen oder Aryl substituierten Reste, vorzugsweise Cyclohexyl, Cyclopentyl oder Cyclopropyl verstanden.A branched or unbranched, optionally substituted C 3 -C6 cycloalkyl radical for R 4 in structural element L means the radicals mentioned above for R 21 , optionally substituted with up to 5 radicals such as halogen or aryl, preferably cyclohexyl, cyclopentyl or cyclopropyl.
Unter C3-C6-Alkenyl- oder C3-C6-Alkinylresten werden für R4 in Strukturelement L die vorstehend für R18 oder R19 erwähnten Reste, vorzugsweise Allyl oder Propargyl verstanden. Besonders bevorzugte Reste für R4 sind Wasserstoff, Methyl, Cyclopropyl, Allyl oder Propargyl, ganz besonders bevorzugt ist Wasserstoff.C 3 -C 6 alkenyl or C 3 -C 6 alkynyl radicals for R 4 in structural element L mean the radicals mentioned above for R 18 or R 19 , preferably allyl or propargyl. Particularly preferred radicals for R 4 are hydrogen, methyl, cyclopropyl, allyl or propargyl; hydrogen is very particularly preferred.
Bei bevorzugten Strukturelementen L ist a = 1, so daß eine ß-Aminosäure die bevorzugte Grundstruktur des Strukturelements L darstellt. Bei besonders bevorzugten Strukturelementen L ist entweder der Rest R2 = Wasserstoff und der Rest R3 breit variabel, wie vorstehend beschrieben, oder der Rest R3 = Wasserstoff und der Rest R2 breit variabel, wie vorstehend beschrieben. Ganz besonders bevorzugt sind Strukturelemente L für die R2 = H und R3 breit variabel, wie vorstehend beschrieben, oder R3 = H und R2 = -NHZ, -NH-S02-Phenyl oder -NH-S02-Benzyl ist, wobei Z die Schutzgruppe Benzoxycarbonyl darstellt.In preferred structural elements L, a = 1, so that a β-amino acid represents the preferred basic structure of structural element L. In particularly preferred structural elements L, either the radical R 2 = hydrogen and the radical R 3 are widely variable, as described above, or the radical R 3 = hydrogen and the radical R 2 are broadly variable, as described above. Structural elements L for which R 2 = H and R 3 are highly variable, as described above, or R 3 = H and R 2 = -NHZ, -NH-S0 2 -phenyl or -NH-S0 2 -benzyl, are very particularly preferred , where Z represents the protective group benzoxycarbonyl.
In Strukturelement G der Formel IG wird unter R5 Wasserstoff und unabhängig von R31 in Strukturelement L, die gleichen Reste wie vorstehend für R31 beschrieben oder eine weitere Seitenketten einer natürlichen Aminosäure verstanden. Bevorzugte Reste R5 sind Wasserstoff, Methyl, Ethinyl oder mit Methyl substituiertes Ethinyl, besonders bevorzugt ist Wasserstoff.In structural element G of formula I G , R 5 is hydrogen and independently of R 31 in structural element L, the same radicals as described above for R 31 or a further side chain of a natural amino acid. Preferred radicals R 5 are hydrogen, methyl, ethynyl or ethynyl substituted with methyl, particularly preferred is hydrogen.
Unter R6 werden unabhängig von R4 die gleichen Reste wie vorstehend für R4 beschrieben verstanden. Bevorzugte Reste R6 sind Wasserstoff, Methyl, Allyl, Propargyl oder Cyclopropyl, besonders bevorzugt ist Wasserstoff.R 6 is understood independently of R 4 to mean the same radicals as described above for R 4 . Preferred radicals R 6 are hydrogen, methyl, allyl, propargyl or cyclopropyl; hydrogen is particularly preferred.
In Strukturelement E der Formel IE wird unter Q ein zweifach gebundener, gegebenenfalls mit bis zu drei weiteren Resten sub- stituierter Heteroarylrest verstanden, wobei gegebenenfalls zwei Reste zusammen einen gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann.In structural element E of the formula I E , Q is understood to mean a double bonded heteroaryl radical which is optionally substituted with up to three further radicals, where two radicals together form a saturated, unsaturated or aromatic carbocycle or heterocycle which has up to three different or identical heteroatoms 0, N, S can contain, and the cycle can optionally be substituted or a further, optionally substituted, saturated, unsaturated or aromatic cycle can be fused onto this cycle.
Unter einem Heteroarylrest wird vorzugsweise ein 5- oderA heteroaryl radical is preferably a 5- or
6 gliedriger, aromatischer Heterocyclus der bis zu drei ver- schiedene oder gleiche Heteroatome 0, N, S enthalten kann, verstanden, wobei bei Heterocyclen die freie Aminprotonen tragen, wie beispielsweise Imidazolyl, Triazolyl, Pyrazolyl oder Pyrrolyl die freien Aminprotonen durch gängige Aminschutzgruppen, wie beispielsweise Methyl, Benzyl, Boc (tert. -Butoxycarbonyl) , Z (Benzoxycarbonyl), Tosyl, -S02-Cι-C4-Alkyl, -S02-Phenyl oder -S0 -Benzyl ersetzt sein können. Als bevorzugte Heteroarylreste Q seien folgende Strukturen aufgezählt, wobei die Verknüpfungsstellen durch einen Bindungsstrich gekennzeichnet sind:6-membered, aromatic heterocycle which may contain up to three different or identical heteroatoms 0, N, S, where heterocycles carry the free amine protons, such as imidazolyl, triazolyl, pyrazolyl or pyrrolyl, the free amine protons by common amine protecting groups, such as for example methyl, benzyl, Boc (tert-butoxycarbonyl), Z (benzoxycarbonyl), tosyl, -S0 2 -Cι-C 4 alkyl, -S0 2 -phenyl or -S0-benzyl can be replaced. The following structures are listed as preferred heteroaryl radicals Q, the connecting sites being identified by a dash:
Als besonders bevorzugte Heteroarylreste Q seien folgende Strukturen aufgezählt, wobei die festgelegten Positionen der Verknüpfungsstellen durch einen Bindungsstrich gekennzeichnet sind und der Einbau der Strukturen in beiden Orientierungen erfolgen kann:The following structures are listed as particularly preferred heteroaryl residues Q, the fixed positions of the linking points being identified by a dash and the incorporation of the structures can take place in both orientations:
Als ganz besonders bevorzugte Heteroarylreste Q seien folgende Strukturen aufgezählt, wobei die festgelegten Positionen der Verknüpfungsstellen durch einen Bindungsstrich gekennzeichnet sind und der Einbau der Strukturen in beiden Orientierungen erfolgen kann: The following structures are listed as very particularly preferred heteroaryl residues Q, the fixed positions of the linking points being identified by a dash and the incorporation of the structures can take place in both orientations:
Wie vorstehend erwähnt können auch bei diesen bevorzugten bzw. besonders bevorzugten Strukturen die freien Aminprotonen von Imidazolyl, Pyrazol, Triazol oder Pyrrolyl durch gängige Amin- schutzgruppen, wie beispielsweise Methyl, Benzyl, Boc (tert.- Butoxycarbonyl ) , Z (Benzoxycarbonyl), Tosyl, -S02-Cι~C4-Alkyl, -S0-Phenyl oder -S0-Benzyl ersetzt sein.As mentioned above, even in these preferred or particularly preferred structures, the free amine protons of imidazolyl, pyrazole, triazole or pyrrolyl can be protected by common amine protective groups, such as, for example, methyl, benzyl, Boc (tert-butoxycarbonyl), Z (benzoxycarbonyl), tosyl , -S0 2 -Cι ~ C 4 alkyl, -S0-phenyl or -S0-benzyl to be replaced.
Bevorzugte Substituenten der Heteroarylreste sind unabhängig voneinander ein oder zwei Reste ausgewählt aus der Gruppe -CN, Halogen, vorzugsweise Cl oder F, Cι-C4-Alkyl, vorzugsweise Methyl, Cι-C-Halogenalkyl, vorzugsweise Trifluormethyl, Cι-C4-Alkoxy, vorzugsweise Methoxy, -NH-Cι-C4-Alkyl oder Aryl, vorzugsweise Phenyl . Preferred substituents of the heteroaryl radicals are independently one or two radicals selected from the group -CN, halogen, preferably Cl or F, -CC 4 alkyl, preferably methyl, -C-haloalkyl, preferably trifluoromethyl, C 1 -C 4 alkoxy , preferably methoxy, -NH-Cι-C 4 alkyl or aryl, preferably phenyl.
Das Strukturelement A bedeutet eines der Strukturelemente der Formel IA 1 bis IA 20 The structural element A means one of the structural elements of the formula I A 1 to I A 20
wobei für das Strukturelement A, die Strukturelemente der Formel IA1, IA2- IA3- IA - IA5 IA8 IA10/ oder IA 13 bevorzugt sind und das Strukturelement der Formel IA 4 wherein for the structural element A, the structural elements of the formula IA 1 , IA 2 - IA 3 - IA - IA 5 IA 8 IA 10 / or I A 13 are preferred and the structural element of the formula I A 4
besonders bevorzugt ist. is particularly preferred.
Die Reste R10 und R11 bedeuten unabhängig voneinander und unabhängig von R3 die vorstehend für R3 im Strukturelement L beschriebenen Reste, vorzugsweise Cι-C4-Alkyl, C3-Cg-Cycloalkyl , Cι-C4-Alkyl-C3-C8-Cycloalkyl, Aryl, Alkylaryl, Heteroaryl oder Alkylheteroaryl, wobei die Aryl-, Alkylaryl-, Heteroaryl- und Alkylheteroarylreste, bis zu drei gleiche oder verschiedene Reste der Gruppe F, Cl, Br oder I, Cι-C4-Alkyl, C3-C6-Cycloalkyl, -COOH, -COOMe, -CF3, -CN, Cι-C4-Alkoxy-, -SCH3, -0-CH2-COOH, Phenyl, -S02CH3, -N02, -OH, -NH2, -N-Pyrrolidinyl, -N-Piperidinyl ,The radicals R 10 and R 11 independently of one another and independently of R 3 are the radicals described above for R 3 in the structural element L, preferably C 1 -C 4 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 4 -alkyl-C 3 -C 8 cycloalkyl, aryl, alkylaryl, heteroaryl or Alkylheteroaryl, the aryl, alkylaryl, heteroaryl and alkylheteroaryl radicals, up to three identical or different radicals from the group F, Cl, Br or I, -CC 4 -alkyl, C 3 -C 6 -cycloalkyl, -COOH, -COOMe, -CF 3 , -CN, -C-C 4 -alkoxy-, -SCH 3 , -0-CH 2 -COOH, phenyl, -S0 2 CH 3 , -N0 2 , -OH, -NH 2 , - N-pyrrolidinyl, -N-piperidinyl,
-N-Morpholinyl, -N-Piperazinyl, -NH-Cχ-C4-Alkyl , -N(Cι~C4-Alkyl) , -NH-CO-Cι-C4-Alkyl, -CO-NH-Cι-C4-Alkyl, -NH-S02-Cι-C4-Alkyl, -S02-NH-Cι-C4-Alkyl, oder -S02-Cι-C-Alkyl, gegebenfalls substituiertes -NH-CO-Phenyl , -CO-NH-Phenyl, -NH-S02-Phenyl, -S02-NH-Phenyl, -NH-CO-Benzyl, -CO-NH-Benzyl, -NH-S0 -Benzyl, -S02-NH-Benzyl, gegebenfalls substituiertes -S02-NT1T2 oder -CO-NT^-T2, wobei die beiden Reste T1 und T2 ein cyclisches Amin bilden können, tragen können,-N-morpholinyl, -N-piperazinyl, -NH-Cχ-C 4 -alkyl, -N (Cι ~ C 4 -alkyl), -NH-CO-Cι-C 4 -alkyl, -CO-NH-Cι- C 4 alkyl, -NH-S0 2 -Cι-C 4 alkyl, -S0 2 -NH-Cι-C 4 alkyl, or -S0 2 -Cι-C-alkyl, optionally substituted -NH-CO-phenyl , -CO-NH-phenyl, -NH-S0 2 -phenyl, -S0 2 -NH-phenyl, -NH-CO-benzyl, -CO-NH-benzyl, -NH-S0-benzyl, -S0 2 -NH -Benzyl, optionally substituted -S0 2 -NT 1 T 2 or -CO-NT ^ -T 2 , where the two radicals T 1 and T 2 can form a cyclic amine,
oder beide Reste R10 und R11 zusammen einen 3 bis 8 gliedrigen, gegebenenfalls substituierten, gesättigten, ungesättigten oder aromatischen N-Heterocyclus der zusätzlich zwei weitere, gleiche oder verschiedene Heteroatome 0, N, oder S enthalten kann, wie beispielsweise Pyrrolidinyl, Piperidinyl, Hexahydroazepinyl, Piperazinyl oder Morpholinyl.or both radicals R 10 and R 11 together form a 3 to 8-membered, optionally substituted, saturated, unsaturated or aromatic N-heterocycle which can additionally contain two further, identical or different heteroatoms 0, N, or S, such as, for example, pyrrolidinyl, piperidinyl, Hexahydroazepinyl, piperazinyl or morpholinyl.
R12 bedeutet einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cχ-C4-Alkyl-, Alkylaryl-, C3-Cg-Cycloalkyl- oder Cι-C4-Alkyl-C-C6-Cycloalkylrest oder einen gegebenenfalls substi- tuierten Arylrest, wie vorstehend für R21 beschrieben.R 12 represents a branched or unbranched, optionally substituted Cχ-C 4 alkyl, alkylaryl, C 3 -Cg cycloalkyl or C 1 -C 4 alkyl CC 6 cycloalkyl radical or an optionally substituted aryl radical, as above described for R 21 .
Unter einem verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkoxy- oder -O-Alkylarylrest werden für R13 die entsprechenden Reste wie vorstehend für R31 beschrieben, vorzugsweise Methoxy oder Benzyloxy verstanden. Die ResteA branched or unbranched, optionally substituted C 1 -C 4 -alkoxy or -O-alkylaryl radical for R 13 is understood to mean the corresponding radicals as described above for R 31 , preferably methoxy or benzyloxy. The rest
-OCO-Cι-C4-Alkyl-, -OCO-Aryl-, -OCO-Alkylaryl- oder -OCO-Allyl- setzen sich aus der Gruppe -OCO- und den vorstehend unter R31 beschrieben Cι-C4-Alkyl-, Aryl-, Alkylarylresten oder dem Allyl- rest zusammen.-OCO -CC 4 -alkyl-, -OCO-aryl-, -OCO-alkylaryl- or -OCO-allyl- consist of the group -OCO- and the above-described C 31 -C 4 -alkyl- , Aryl, alkylaryl radicals or the allyl radical together.
Bevorzugte Reste für R13 sind Wasserstoff, -OH, -O-Benzyl, -OCO-Phenyl, -OCO-Benzyl, -OCO-Allyl, -CN oder -C0-NH2.Preferred radicals for R 13 are hydrogen, -OH, -O-benzyl, -OCO-phenyl, -OCO-benzyl, -OCO-allyl, -CN or -C0-NH 2 .
Analog setzen sich die Reste -C02-Cι_4-Alkyl-, -C02-Alkylaryl-, -C02-Allyl-, -CO-Cι-C4-Alkyl-, -CO-Alkylaryl- oder -CO-Allylrest für den Rest R14 aus der Gruppe -C002- bzw. -CO- und den vorstehend unter R31 beschrieben Cι-C4-Alkyl-, Arylrest oder dem Allylrest zusammen. Bevorzugte Reste für R14 sind Wasserstoff, Methyl, Benzyl, -COO-Benzyl, -COO-Allyl, -CO-Benzyl oder -CO-Allyl. R15 bedeutet Wasserstoff, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι~C4-Alkylrest oder einen gegebenenfalls substituierten Aryl- oder Alkylarylrest, wie vorstehend für R21 oder R4 beschrieben. Bevorzugte Reste für R15 sind Wasserstoff, Methyl, Benzyl oder Phenyl.Analogously, the radicals -C0 2 -Cι_ 4 alkyl, -C0 2 alkylaryl, -C0 2 allyl, -CO-Cι-C 4 alkyl, -CO-alkylaryl or -CO-allyl radical for the radical R 14 from the group -C00 2 - or -CO- and the C 1 -C 4 -alkyl, aryl radical or the allyl radical described above under R 31 together. Preferred radicals for R 14 are hydrogen, methyl, benzyl, -COO-benzyl, -COO-allyl, -CO-benzyl or -CO-allyl. R 15 denotes hydrogen, a branched or unbranched, optionally substituted C 1 -C 4 -alkyl radical or an optionally substituted aryl or alkylaryl radical, as described above for R 21 or R 4 . Preferred radicals for R 15 are hydrogen, methyl, benzyl or phenyl.
R16, R17 bedeuten unabhängig voneinander -NH , Halogen, wie Cl, Br, I oder F oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-oder Cι-C4-Alkoxy- oder einen gegebenfalls substituierten Arylrest, wie vorstehend für R31 beschrieben, vorzugsweise NH2, Cl, F, Methyl, Methoxy oder Phenyl.R 16, R 17 are independently -NH, halogen, such as Cl, Br, I or F or a branched or unbranched, optionally substituted Cι-C4 alkyl or Cι-C 4 alkoxy or an optionally substituted aryl radical, as described above for R 31 , preferably NH 2 , Cl, F, methyl, methoxy or phenyl.
Z1 ' Z2 ' Z3 ' Z4 bedeuten unabhängig voneinander CH, C-CH3, C-OCH3/ C-Cl oder N wobei vorzugsweise Z1 und Z2 oder Z2 und Z3 oder Z3 und Z4 nicht gleichzeitig N sind.Z 1 ' Z 2 ' Z 3 ' Z 4 independently of one another are CH, C-CH 3 , C-OCH 3 / C-Cl or N, preferably Z 1 and Z 2 or Z 2 and Z 3 or Z 3 and Z 4 are not N at the same time.
Wenn nicht näher spezifiziert, werden in der Beschreibung unter substituierten Aryl-, Alkylaryl-, Heteroaryl- oder Alkylhetero- arylresten Aryl-, Alkylaryl-, Heteroaryl- oder Alkylheteroaryl- reste verstanden, die mit bis zu drei gleichen oder verschiedenen Resten, ausgewählt aus der folgenden Gruppe substituiert sein können:Unless otherwise specified, substituted aryl, alkylaryl, heteroaryl or alkylheteroaryl radicals are understood in the description to mean aryl, alkylaryl, heteroaryl or alkylheteroaryl radicals which have up to three identical or different radicals selected from the group the following group can be substituted:
-N02, -NH -OH, -CN, -COOH, -0-CH2-COOH, -COO-Cι-C4-Alkyl, Halogen, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-, C3-C6-Cycloalkyl-, Cι-C4~Alkoxy-, Cι-C4-Thioalkyl-, -0-CH2-COO-Cι-C4-Alkyl, -NH-CO-Cι-C4-Alkyl, -CO-NH-Cι-C4-Alkyl, -NH-S02-Cι-C4-Alkyl, -S02-NH-Cι-C4-Alkyl, -N(Cι-C4-Alkyl)2, -NH-Cι-C-Alkyl-, oder -S02-Cι-4-Alkylrest, einen gegebenenfalls substituierten -NH-CO-Phenyl, -CO-NH-Phenyl, -NH-S02-Phenyl, -S0 -NH-Phenyl, -NH-CO-Benzyl , -CO-NH-Benzyl , -NH-S02-Benzyl, -S02-NH-Benzyl, einen gegebenfalls substituierten Rest -S0-NT1T2 oder -CO-NT1^ wobei die beiden Reste T1 und T2 ein cyclisches Amin bilden können, oder einen 3 bis 6 gliedrigen, gegebenenfalls substituierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, oder zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann darstellen und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter Cyclus ankondensiert sein kann. Die Verbindungen der Formel I und auch die Zwischenprodukte zu ihrer Herstellung, können ein oder mehrere asymmetrische substituierte Kohlenstoffatome besitzen. Die Verbindungen können als reine Enantiomere bzw. reine Diastereomere oder als deren Mischung vorliegen. Bevorzugt ist die Verwendung einer enantiomerenreinen Verbindung als Wirkstoff.-N0 2 , -NH -OH, -CN, -COOH, -0-CH 2 -COOH, -COO-Cι-C 4 alkyl, halogen, a branched or unbranched, optionally substituted Cι-C 4 alkyl, C 3 -C 6 -cycloalkyl-, -C-C 4 ~ alkoxy-, -C-C 4 -thioalkyl-, -0-CH 2 -COO-Cι-C 4 alkyl, -NH-CO-Cι-C 4 - Alkyl, -CO-NH -CC 4 -alkyl, -NH-S0 2 -Cι-C 4 -alkyl, -S0 2 -NH-Cι-C 4 -alkyl, -N (-C-C 4 -alkyl) 2 , -NH -CC-alkyl, or -S0 2 -Cι- 4 alkyl, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-S0 2 -phenyl, -S0 -NH-phenyl, -NH-CO-benzyl, -CO-NH-benzyl, -NH-S0 2 -benzyl, -S0 2 -NH-benzyl, an optionally substituted radical -S0-NT 1 T 2 or -CO- NT 1 ^ where the two radicals T 1 and T 2 can form a cyclic amine, or a 3 to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle which has up to three different or identical heteroatoms 0, N, S may contain, or two residues together a fused, saturated , unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S and the cycle can be optionally substituted or a further, optionally substituted cycle can be fused onto this cycle. The compounds of the formula I and also the intermediates for their preparation can have one or more asymmetrically substituted carbon atoms. The compounds can exist as pure enantiomers or pure diastereomers or as a mixture thereof. The use of an enantiomerically pure compound as the active ingredient is preferred.
Die Verbindungen der Formel I können auch in Form von physiologisch verträglichen Salzen vorliegen.The compounds of the formula I can also be in the form of physiologically tolerable salts.
Die Verbindungen der Formel I können auch als Prodrugs in einer Form vorliegen, in der die Verbindungen der Formel I unter physiologischen Bedingungen freigesetzt werden. Beispielhaft sei hier auf die Gruppe T in Strukturelement L verwiesen, die teil- weise Gruppen enthält, die unter physiologischen Bedingungen zur freien Carbonsäuregruppe hydrolisierbar sind. Es sind auch derivatisierte Strukturelemente A geeignet, die das Strukturelement A unter physiologischen Bedingungen freisetzen.The compounds of the formula I can also be present as prodrugs in a form in which the compounds of the formula I are released under physiological conditions. As an example, reference is made here to group T in structural element L, some of which contains groups which can be hydrolyzed to the free carboxylic acid group under physiological conditions. Derivatized structural elements A which release the structural element A under physiological conditions are also suitable.
In einer bevorzugten Ausführungsform der Verbindungen derIn a preferred embodiment of the compounds of
Formel I, werden die Indizes a, e, f und g sowie der Heterocyclus Q so gewählt, daß der Abstand zwischen der Gruppe T und dem Strukturelement A, 10 bis 14 Atombindungen, vorzugsweise 11 bis 13 Atombindungen entlang des kürzestmöglichen Weges entlang des Molekülgerüstes beträgt.Formula I, the indices a, e, f and g and the heterocycle Q are chosen so that the distance between the group T and the structural element A is 10 to 14 atomic bonds, preferably 11 to 13 atomic bonds along the shortest possible path along the molecular structure .
Weitere bevorzugte Verbindungen der Formel I weisen die bevorzugten Strukturelemente A der Formel IA 1, IA 2 IA3, IA 4/ IA 5 A 8 IA 10/ oder IA 13 auf, während die Strukturelemente E, G und L wie vorstehend beschrieben weit variabel sind.Further preferred compounds of the formula I have the preferred structural elements A of the formula I A 1 , I A 2 IA 3 , I A 4 / I A 5 A 8 I A 10 / or I A 13 , while the structural elements E, G and L are widely variable as described above.
Weitere bevorzugte Verbindungen der Formel I weisen das besonders bevorzugte Strukturelement A der Formel IA 4 auf, während die Strukturelemente E, G und L wie vorstehend beschrieben weit variabel sind.Further preferred compounds of the formula I have the particularly preferred structural element A of the formula I A 4 , while the structural elements E, G and L are widely variable as described above.
Besonders bevorzugte Verbindungen der Formel I weisen die bevorzugten Strukturelemente A der Formel IA 1, IA2/ IA3, IA / IA5» A8/ IA 10, oder IA 13 und den bevorzugten Bereich des Strukturelements L auf, während die Strukturelemente E und G wie vorstehend beschrieben weit variabel sind.Particularly preferred compounds of the formula I have the preferred structural elements A of the formula I A 1 , IA 2 / IA 3 , IA / IA 5 »A 8 / I A 10 , or I A 13 and the preferred region of the structural element L, while the Structural elements E and G are widely variable as described above.
Weitere besonders bevorzugte Verbindungen der Formel I weisen das besonders bevorzugte Strukturelement A der Formel IA 4 und den bevorzugten Bereich des Strukturelements L auf, während die Strukturelemente E und G wie vorstehend beschrieben weit variabel sind. Weitere besonders bevorzugte Verbindungen der Formel I weisen das bevorzugte Strukturelement A der Formel IA 4 und den bevorzugten Bereich des Strukturelements E auf, während die Strukturelemente L und G wie vorstehend beschrieben weit variabel sind.Further particularly preferred compounds of the formula I have the particularly preferred structural element A of the formula I A 4 and the preferred region of the structural element L, while the structural elements E and G are widely variable as described above. Further particularly preferred compounds of the formula I have the preferred structural element A of the formula I A 4 and the preferred region of the structural element E, while the structural elements L and G are widely variable as described above.
Ganz besonders bevorzugte Verbindungen der Formel I weisen das bevorzugte Strukturelement A der Formel IA 4, den bevorzugten Bereich des Strukturelements E und den bevorzugten Bereich des Strukturelements L auf, während das Strukturelement G wie vor- stehend beschrieben weit variabel ist.Very particularly preferred compounds of the formula I have the preferred structural element A of the formula I A 4 , the preferred region of the structural element E and the preferred region of the structural element L, while the structural element G is widely variable as described above.
Weitere ganz besonders bevorzugte Verbindungen der Formel I weisen den bevorzugten Bereich des Strukturelements A, den bevorzugten Bereich des Strukturelements E und den bevorzugten Bereich des Strukturelements G auf, während das Strukturelemente L wie vorstehend beschrieben weit variabel ist.Other very particularly preferred compounds of the formula I have the preferred region of the structural element A, the preferred region of the structural element E and the preferred region of the structural element G, while the structural element L is widely variable as described above.
Äußerst bevorzugte Verbindungen der Formel I weisen das bevorzugte Strukturelement A der Formel IA 4 und die bevorzugten Bereiche der Strukturelemente E, G und L auf.Extremely preferred compounds of the formula I have the preferred structural element A of the formula I A 4 and the preferred regions of the structural elements E, G and L.
Ganz bevorzugte Verbindungen der Formel I sind im folgenden aufgelistet, wobei „Verbindungsnummer" für die Nummer einer individualisierten Verbindungen A-E-G-L der Formel I steht, die Verbindungsnummer und die jeweilige Verbindung durch einen Doppelpunkt getrennt sind und die Bedeutung der Abkürzungen der Strukturelemente A-E-G-L nach der Tabelle erläutert wird. Very preferred compounds of the formula I are listed below, where “compound number” stands for the number of an individualized compound AEGL of the formula I, the compound number and the respective compound are separated by a colon and the meaning of the abbreviations of the structural elements AEGL according to the table becomes.
Verbindungsnummer: A-E-G-LConnection number: A-E-G-L
1 : bhs-25thiaz-nmgly-betaoxaz 5 2: phhs-24thiaz-bala-betabph1: bhs-25thiaz-nmgly-betaoxaz 5 2: phhs-24thiaz-bala-betabph
3: bhs-25thiaz-ser-betapy3: bras-25thiaz-ser-betapy
4 : thazep-24thiaz-gly-betal3bendi4: thazep-24thiaz-gly-betal3bendi
5: bim-24thiaz-gly-betatrif5: bim-24thiaz-gly-betatrif
6: bhs-24thioph-gly-betapyee6: bhs-24thioph-gly-betapyee
7 : bhs-me25thioph-ala-beta34meoph7: bhs-me25thioph-ala-beta34meoph
1010
8: tolhs-24thioph-gly-betafbph8: tolhs-24thioph-gly-betafbph
9: tolhs-24thioph-gly-betameph9: tolhs-24thioph-gly-betameph
10: bim-me24thiaz-bala-betaph10: bim-me24thiaz-bala-betaph
11 : bhs-me25thioph-leu-beta34meoph11: bhs-me25thioph-leu-beta34meoph
12: ibhs-24thioph-gly-betathiome 15 13: bhs-nme35pyr-gly-betabthioph12: ibhs-24thioph-gly-betathiome 15 13: bhs-nme35pyr-gly-betabthioph
14: tolhs-nme35pyr-gly-betafu214: tolhs-nme35pyr-gly-betafu2
15: bhs-ithiadiaz-gly-betahmofu15: bhs-ithiadiaz-gly-betahmofu
16 : phhs-nme35pyr-bala-betacph16: phhs-nme35pyr-bala-betacph
17: impy-24thiaz-bala-betafu3 20 18: tolhs-25methiaz-bala-psdaptb17: impy-24thiaz-bala-betafu3 20 18: tolhs-25methiaz-bala-psdaptb
19: sabhs-25thiaz-gly-psdap19: sabhs-25thiaz-gly-psdap
20: bhs-24thioph-gly-betadcphtb20: bhs-24thioph-gly-betadcphtb
21: 2py-nme35pyr-leu-psdap21: 2py-nme35pyr-leu-psdap
22: bhs-nme35pyr-gly-aspbzla22: bhs-nme35pyr-gly-aspbzla
23: phhs-me24thiaz-gly-zdap23: phhs-me24thiaz-gly-zdap
2525
24: bhs-25thiaz-bala-betameph24: bras-25thiaz-bala-betameph
25: phhs-me24thiaz-ala-beta34meoph25: phhs-me24thiaz-ala-beta34meoph
26 : tolhs-25methiaz-gly-beta34meoph26: tolhs-25methiaz-gly-beta34meoph
27: ibhs-ithiadiaz-gly-betafbph27: ibhs-ithiadiaz-gly-betafbph
28: tolhs-ithiadiaz-bala-asppha 30 29: phhs-ithiadiaz-bala-betaamibe28: tolhs-ithiadiaz-bala-asppha 30 29: phhs-ithiadiaz-bala-betaamibe
30: tolhs-24thioph-bala-betabmph30: tolhs-24thioph-bala-betabmph
31 : phhs-25methiaz-bala-betaol31: phhs-25methiaz-bala-betaol
32: bhs-25oxaz-bala-betamethi32: bras-25oxaz-bala-betamethi
33: ibhs-24thiaz-bala-betahni 35 34: gua-24thiaz-gly-betaftrif33: ibhs-24thiaz-bala-betahni 35 34: gua-24thiaz-gly-betaftrif
35 : bhs-24thiaz-gly-betafphe 36: tolhs-oxadiaz-gly-psdaptb35: bhs-24thiaz-gly-beta 36: tolhs-oxadiaz-gly-psdaptb
37 : phhs-25methiaz-bala-betatbuph 38: bhs-24thiaz-nmgly-betathio3 39 : phhs-24thioph-gly-betatos37: phhs-25methiaz-bala-betatbuph 38: bhs-24thiaz-nmgly-betathio3 39: phhs-24thioph-gly-betatos
40 40: 2py-thiadiaz-leu-psdap 41: dhim-35py-gly-betameph 42 : bhs-ithiadiaz-gly-aspaba 43 : phhs-oxadiaz-gly-beta4bph 44 : bhs-25thiaz-gly-csdap 45 45: ibhs-25thiaz-gly-betahph40 40: 2py-thiadiaz-leu-psdap 41: dhim-35py-gly-betameph 42: bhs-ithiadiaz-gly-aspaba 43: phhs-oxadiaz-gly-beta4bph 44: bhs-25thiaz-gly-csdap 45 45 : ibhs -25thiaz-gly-betahph
46 : phhs-25methiaz-gly-betahdbph 47: bim-me25thioph-gly-betaph 48: ibhs-ithiadiaz-bala-beta3quin46: phhs-25methiaz-gly-betahdbph 47: bim-me25thioph-gly-betaph 48: ibhs-ithiadiaz-bala-beta3quin
49: tolhs-oxadiaz-gly-betadhbfu49: tolhs-oxadiaz-gly-betadhbfu
50: bhs-oxadiaz-leu-psdap50: bras-oxadiaz-leu-psdap
51: impy-24thioph-bala-betainyl 5 52: bhs-25methiaz-ala-beta23meoph51: impy-24thioph-bala-betainyl 5 52: bhs-25methiaz-ala-beta23meoph
53: phhs-24thiaz-gly-betabnaphth53: phhs-24thiaz-gly-betabnaphth
54 : impy-42nmeim-b la-betathiome54: impy-42nmeim-b la-betathiome
55: bim-35thioph-ala-betadcph55: bim-35thioph-ala-betadcph
56: 2py-me24thiaz-gly-betapy56: 2py-me24thiaz-gly-betapy
57: phhs-24thioph-bala-betaimid57: phhs-24thioph-bala-betaimide
10 58: phhs-24thioph-gly-betadhbfu10 58: phhs-24thioph-gly-betadhbfu
59: phhs-nme35pyr-bala-betaibph59: phhs-nme35pyr-bala-betaibph
60: bhs-25thiaz-ser-betameph60: bras-25thiaz-ser-betameph
61: tolhs-25thiaz-bala-zdap61: tolhs-25thiaz-bala-zdap
62: bim-25thiaz-gly-betadcph 15 63 : 2pmhs-42nmeim-gly-betaamibe62: bim-25thiaz-gly-betadcph 15 63 : 2 pmhs-42nmeim-gly-betaamibe
64: 2py-24thioph-gly-beta3quin64: 2py-24thioph-gly-beta3quin
65 : bhs-25methiaz-gly-betamethioph65: bhs-25methiaz-gly-betamethioph
66: tolhs-ithiadiaz-gly-betafbph66: tolhs-ithiadiaz-gly-betafbph
67: phhs-25methiaz-gly-betamethi 2o 68: ibhs-24thiaz-gly-betadtrif67: phhs-25methiaz-gly-betamethi 2o 68: ibhs-24thiaz-gly-betadtrif
69: bhs-24thioph-gly-betabthioph69: bhs-24thioph-gly-betabthioph
70: tolhs-25oxaz-gly-betabmph70: tolhs-25oxaz-gly-betabmph
71: ibhs-ithiadiaz-bala-suabu71: ibhs-ithiadiaz-bala-suabu
72 : bhs-42oxaz-gly-betapy72: bhs-42oxaz-gly-betapy
73 : tolhs-ithiadiaz-gly-betapyr73: tolhs-ithiadiaz-gly-betapyr
25 74: 2py-24im-gly-psdap25 74: 2py-24im-gly-psdap
75: thpy -24thiaz-gly-betadcph75: thpy-24thiaz-gly-betadcph
76: phhs-24thiaz-gly-betampy76: phhs-24thiaz-gly-betampy
77: bhs-25methiaz-bala-betadito77: bras-25methiaz-bala-betadito
78 : phhs-25methiaz-bala-suabu 30 79: bhs-25thiaz-bala-beta23meoph78: phhs-25methiaz-bala-suabu 30 79: bhs-25thiaz-bala-beta23meoph
80 : bhs-oxadiaz-leu-betapy80: bras-oxadiaz-leu-betapy
81: tolhs-25oxaz-gly-betabnaphth81: tolhs-25oxaz-gly-betabnaphth
82: dhim-25thiaz-ala-zdap82: dhim-25thiaz-ala-zdap
83 : tolhs-ithiadiaz-gly-betaimid 35 84: bhs-ithiadiaz-bala-betaoxaz83: tolhs-ithiadiaz-gly-betaimid 35 84: bhs-ithiadiaz-bala-betaoxaz
85: bim-25thioph-ala-betameph85: bim-25thioph-ala-betameph
86: phhs-25oxaz-bala-beta4bph86: phhs-25oxaz-bala-beta4bph
87 : bhs-nme35pyr-nmgly-betainyl87: bhs-nme35pyr-nmgly-betainyl
88: phhs-24thiaz-bala-betacbph88: phhs-24thiaz-bala-betacbph
89 : bhs-25oxaz-bala-betaet89: bras-25oxaz-bala-betaet
40 90: bhs-24thioph-bala-betabmph40 90: bhs-24thioph-bala-betabmph
91: bhs-25oxaz-ala-betaanaphth91: bhs-25oxaz-ala-betaanaphth
92 : ibhs-ithiadiaz-gly-betathiobe92: ibhs-ithiadiaz-gly-betathiobe
93: bhs-25thiaz-bala-betadito93: bras-25thiaz-bala-betadito
94: 2py-nme35pyr-bala-betapy 45 95; tolhs-25oxaz-bala-beta3quin94: 2py-nme35pyr-bala-betapy 45 95; tolhs-25oxaz-bala-beta3quin
96: bhs-25thiaz-gly-beta23meoph96: bhs-25thiaz-gly-beta23meoph
97: 2py-25methiaz-gly-betadito 98 : ibhs-nme35pyr-bala-betahni97: 2py-25methiaz-gly-betadito 98: ibhs-nme35pyr-bala-betahni
99: tolhs-nme35pyr-gly-betadmph99: tolhs-nme35pyr-gly-betadmph
100: ibhs-ithiadiaz-bala-betabdimo100: ibhs-ithiadiaz-bala-betabdimo
101: 2py-24thiaz-gly-aspibua 5 102: ibhs-nme35pyr-bala-betacbph101: 2py-24thiaz-gly-aspibua 5 102: ibhs-nme35pyr-bala-betacbph
103: bhs-24thiazme-gly-zdap103: bhs-24thiazme-gly-zdap
104: bhs-24thioph-bala-betaol104: bhs-24thioph-bala-betaol
105: 2py-24im-gly-zdap105: 2py-24im-gly-zdap
106: tolhs-25methiaz-gly-betapytb106: tolhs-25methiaz-gly-betapytb
107: tolhs-ithiadiaz-gly-psdap107: tolhs-ithiadiaz-gly-psdap
108: phhs-25thiaz-bala-betabthioph108: phhs-25thiaz-bala-betabthioph
109: bhs-nme35pyr-gly-betafph109: bhs-nme35pyr-gly-betafph
110: bhs-25methiaz-ala-betadhbfu110: bhs-25methiaz-ala-betadhbfu
111: bim-25fur-ala-psdap111: bim-25fur-ala-psdap
112: 2pmhs-24thiaz-gly-betapy 15 H3: bhs-24thiaz-bala-betaphethio112: 2 pmhs-24thiaz-gly-betapy 15 H3: bhs-24thiaz-bala-betaphethio
114: bhs-25methiaz-bala-betapytb114: bhs-25methiaz-bala-betapytb
115: bhs-25methiaz-bala-betambiph115: bras-25methiaz-bala-betambiph
116: ibhs-25thiaz-gly-betainyl116: ibhs-25thiaz-gly-betainyl
117 : phhs-nme35pyr-bala-betabthioph 20 H8: bhs-25thiaz-bala-betacph117: phhs-nme35pyr-bala-betabthioph 20 H8: bhs-25thiaz-bala-betacph
119: bim-26py-ala-betadcph119: bim-26py-ala-betadcph
120 : phhs-24thioph-gly-betaphethio120: phhs-24thioph-gly-betaphethio
121: gua-24 hiaz-gly-betabthioph121: gua-24 hiaz-gly-beta thioph
122: phhs-24thioph-bala-betaph122: phhs-24thioph-bala-betaph
123: bhs-25thiaz-gly-betaibph123: bhs-25thiaz-gly-betaibph
124: ibhs-nme35pyr-bala-betathio3124: ibhs-nme35pyr-bala-betathio3
125: tolhs-oxadiaz-gly-betapy125: tolhs-oxadiaz-gly-betapy
126: tolhs-nme35pyr-bala-beta4bph 127: 2py-me24oxaz-gly-betadcph126: tolhs-nme35pyr-bala-beta4bph 127: 2py-me24oxaz-gly-betadcph
128 : tolhs-25methiaz-bala-psdapee 30 129: bhs-ithiadiaz-gly-suabu128: tolhs-25methiaz-bala-psdapee 30 129: bhs-ithiadiaz-gly-suabu
130: ibhs-25methiaz-bala-beta3quin 131 : phhs-25oxaz-gly-betaipr130: ibhs-25methiaz-bala-beta3quin 131: phhs-25oxaz-gly-betaipr
132: bim-53pyrazo-ala-betadcph132: bim-53pyrazo-ala-betadcph
133: tolhs-25oxaz-gly-betapym 35 134: phhs-25oxaz-gly-betathiobe133: tolhs-25oxaz-gly-betapym 35 134: phhs-25oxaz-gly-betathiobe
135: phhs-me24thioph-ala-betaph135: phhs-me24thioph-ala-betaph
136: tolhs-me25thiaz-leu-betapy136: tolhs-me25thiaz-leu-betapy
137 : hs-25thiaz-bala-betapy137: hs-25thiaz-bala-betapy
138: bim-42nmeim-leu-betapy138: bim-42nmeim-leu-betapy
139 : tolhs-nme35pyr-bala-betampy139: tolhs-nme35pyr-bala-betampy
140: bhs-24thioph-gly-betahdcph140: bhs-24thioph-gly-betahdcph
141: ibhs-25oxaz-gly-betaimid141: ibhs-25oxaz-gly-betaimid
142 : bhs-oxadiaz-gly-csdap142: bhs-oxadiaz-gly-csdap
143: ibhs-25oxaz-gly-betadtrif143: ibhs-25oxaz-gly-betadtrif
144: 2py-53pyrazo-ala-betapy 45 145: phhs-nme35pyr-gly-betahdbph144: 2py-53pyrazo-ala-betapy 45 145: phhs-nme35pyr-gly-betahdbph
146: tolhs-oxadiaz-bala-zdapch146: tolhs-oxadiaz-bala-zdapch
147 : phhs-oxadiaz-bala-betapych 148: bim-24thioph-gly-betatrif147: phhs-oxadiaz-bala-betapych 148: bim-24thioph-gly-betatrif
149: tolhs-25methiaz-bala-betapyr149: tolhs-25methiaz-bala-betapyr
150: 2py-24thiaz-ala-betapy150: 2py-24thiaz-ala-betapy
151: bhs-25thiaz-gly-betapytb 5 152: tolhs-25oxaz-gly-zdapch151: bhs-25thiaz-gly-betapytb 5 152: tolhs-25oxaz-gly-zdapch
153: bhs-25methiaz-ala-betadcph153: bras-25methiaz-ala-betadcph
154: ibhs-25methiaz-gly-betatos154: ibhs-25methiaz-gly-betatos
155: tolhs-25thiaz-gly-beta35dbph155: tolhs-25thiaz-gly-beta35dbph
156: bim-me24thioph-leu-betadcph156: bim-me24thioph-leu-betadcph
157: bim-nme35pyr-gly-aspbzla157: bim-nme35pyr-gly-aspbzla
10 158: ibhs-24thioph-bala-ibsdap10 158: ibhs-24thioph-bala-ibsdap
159: gua-24thiaz-gly-betal3bendi159: gua-24thiaz-gly-betal3bendi
160: 2py-25methiaz-gly-psdap160: 2py-25methiaz-gly-psdap
161: 2py-24thiaz-bala-asppha161: 2py-24thiaz-bala-asppha
162 : ibhs-ithiadiaz-bala-betaanaphth 15 163: bhs-nme35pyr-ala-betameph162: ibhs-ithiadiaz-bala-betaanaphth 15 163: bhs-nme35pyr-ala-betameph
164: tolhs-oxadiaz-gly-betapym164: tolhs-oxadiaz-gly-betapym
165: phhs-ithiadiaz-gly-betaph165: phhs-ithiadiaz-gly-betaph
166 : phhs-25methiaz-bala-betadcphtb166: phhs-25methiaz-bala-betadcphtb
167: 2pmhs-24thiaz-gly-betaph 20 168: gua-24oxaz-gly-betafbph167: 2 pmhs-24thiaz-gly-betaph 20 168: gua-24oxaz-gly-betafbph
169: bhs-25oxaz-phg-betapy169: bhs-25oxaz-phg-betapy
170: bhs-25methiaz-bala-betahdbph170: bras-25methiaz-bala-betahdbph
171 : 2py-me24thiaz-bala-beta34meoph171: 2py-me24thiaz-bala-beta34meoph
172: bhs-25thiaz-bala-betambiph172: bhs-25thiaz-bala-betambiph
173: phhs-25methiaz-bala-betadmph173: phhs-25methiaz-bala-betadmph
25 174: bhs-oxadiaz-gly-zdapch25 174: bhs-oxadiaz-gly-zdapch
175: dhim-25thioph-gly-betadcph175: dhim-25thioph-gly-betadcph
176: bhs-me25oxaz-gly-zdap176: bhs-me25oxaz-gly-zdap
177: ibhs-oxadiaz-gly-betahmo177: ibhs-oxadiaz-gly-betahmo
178: ibhs-25thiaz-gly-betadcph 30 179: 2py-35fur-gly-zdap178: ibhs-25thiaz-gly-betadcph 30 179: 2py-35fur-gly-zdap
180: bhs-24thiaz-ala-betal3bendi180: bhs-24thiaz-ala-betal3bendi
181: bhs-oxadiaz-gly-betadcph181: bras-oxadiaz-gly-betadcph
182: phhs-oxadiaz-bala-betah35dc182: phhs-oxadiaz-bala-betah35dc
183 : ibhs-oxadiaz-bala-betaet 35 184: phhs-nme35pyr-gly-betadmph183: ibhs-oxadiaz-bala-betet 35 184: phhs-nme35pyr-gly-betadmph
185: phhs-me24thioph-bala-betapy185: phhs-me24thioph-bala-betapy
186: tolhs-25oxaz-gly-beta34dcph186: tolhs-25oxaz-gly-beta34dcph
187: bim-26py-gly-betameph187: bim-26py-gly-betameph
188: ibhs-24thiaz-gly-betadcphee188: ibhs-24thiaz-gly-betadcphee
189: phhs-25thiaz-gly-betacbph189: phhs-25thiaz-gly-betacbph
40 190 : tolhs-ithiadiaz-gly-betaphethioa40 190: tolhs-ithiadiaz-gly-betaphethioa
191: bhs-25methiaz-gly-betafu2191: bhs-25methiaz-gly-betafu2
192: 2pmhs-42nmeim-gly-betabenfu192: 2 pmhs-42nmeim-gly-betabenfu
193: bhs-25methiaz-gly-beta3quin193: bhs-25methiaz-gly-beta3quin
194 : tolhs-25thiaz-bala-betahdcph 45 195: 2py-24thioph-bala-betadcph194: tolhs-25thiaz-bala-betahdcph 45 195: 2py-24thioph-bala-betadcph
196: 2py-42nmeim-ala-zdap196: 2py-42nmeim-ala-zdap
197: bim-35thioph-gly-betapy 198: bim-me25thioph-leu-zdap197: bim-35thioph-gly-betapy 198: bim-me25thioph-leu-zdap
199: bim-25methiaz-bala-betapy199: bim-25methiaz-bala-betapy
200: tolhs-25thiaz-bala-betaoxaz200: tolhs-25thiaz-bala-betaoxaz
201: phhs-25oxaz-gly-betapbiph 5 202: tolhs-24thioph-bala-ibsdap201: phhs-25oxaz-gly-betapbiph 5 202: tolhs-24thioph-bala-ibsdap
203: bhs-oxadiaz-gly-zdaptb203: bhs-oxadiaz-gly-zdaptb
204: bim-42oxaz-leu-betapy204: bim-42oxaz-leu-betapy
205: ibhs-25methiaz-gly-zdaptb205: ibhs-25methiaz-gly-zdaptb
206: ibhs-25methiaz-gly-betaol206: ibhs-25methiaz-gly-betaol
207 : tolhs-ithiadiaz-gly-beta34dcph207: tolhs-ithiadiaz-gly-beta34dcph
208: phhs-ithiadiaz-gly-betacthioph208: phhs-ithiadiaz-gly-betacthioph
209: phhs-24thiaz-bala-betahmofu209: phhs-24thiaz-bala-betahmofu
210: phhs-ithiadiaz-gly-aspibua210: phhs-ithiadiaz-gly-aspibua
211: phhs-24thiaz-gly-betathioph211: phhs-24thiaz-gly-betathioph
212: bhs-25methiaz-gly-betaimid 15 213: gua-25thiaz-gly-betahdcph212: bhs-25methiaz-gly-betaimide 15 213: gua-25thiaz-gly-betahdcph
214: bhs-25thiaz-ala-betacph214: bhs-25thiaz-ala-betacph
215: gua-24thiaz-gly-betaet215: gua-24thiaz-gly-betet
216: tolhs-25methiaz-bala-betahcbph216: tolhs-25methiaz-bala-betahcbph
217: tolhs-ithiadiaz-gly-beta35dbph 20 218: ibhs-oxadiaz-gly-betadbph217: tolhs-ithiadiaz-gly-beta35dbph 20 218: ibhs-oxadiaz-gly-betadbph
219 : tolhs-24thioph-gly-betathioph219: tolhs-24thioph-gly-betathioph
220: bim-53pyrazo-bala-zdap220: bim-53pyrazo-bala-zdap
221: bim-me24oxaz-gly-betadcph221: bim-me24oxaz-gly-betadcph
222: bim-triaz-gly-psdap222: bim-triaz-gly-psdap
223: phhs-25thiaz-bala-betampy223: phhs-25thiaz-bala-betampy
224: bhs-oxadiaz-gly-betadcphee224: bras-oxadiaz-gly-betadcphee
225: bim-ithiadiaz-leu-zdap225: bim-ithiadiaz-leu-zdap
226: 2pmhs-24thiaz-gly-betafph226: 2 pmhs-24thiaz-gly-betafph
227: bhs-25thiaz-gly-betathioph227: bhs-25thiaz-gly-betathioph
228: gua-24thiaz-bala-betadcph 30 229: impy-42nmeim-bala-betafph228: gua-24thiaz-bala-betadcph 30 229: impy-42nmeim-bala-betafph
230: tolhs-24thioph-gly-betadmoph 231: ibhs-oxadiaz-bala-betapbiph 232: ibhs-25methiaz-bala-zdapee 233: tolhs-oxadiaz-gly-betafph230: tolhs-24thioph-gly-betadmoph 231: ibhs-oxadiaz-bala-betapbiph 232: ibhs-25methiaz-bala-zdapee 233: tolhs-oxadiaz-gly-betafph
35 234: bhs-me24oxaz-bala-beta34meoph 235: tolhs-25methiaz-bala-betahbcph 236: bim-42oxaz-leu-betadcph 237: tolhs-oxadiaz-gly-busu2be 238: tolhs-me25thiaz-ala-betapy35 234: bhs-me24oxaz-bala-beta34meoph 235: tolhs-25methiaz-bala-betahbcph 236: bim-42oxaz-leu-betadcph 237: tolhs-oxadiaz-gly-busu2be 238: tolhs-me25thiaz-ala-betapy
239: phhs-oxadiaz-bala-betainyl239: phhs-oxadiaz-bala-betainyl
40 240: bhs-oxadiaz-gly-psdaptb40 240: bhs-oxadiaz-gly-psdaptb
241: phhs-24thiaz-gly-busu2be241: phhs-24thiaz-gly-busu2be
242: tolhs-25methiaz-bala-zdapee242: tolhs-25methiaz-bala-zdapee
243: bhs-25thiaz-nmgly-betahmph243: bhs-25thiaz-nmgly-betahmph
244: bhs-oxadiaz-gly-betapy244: bras-oxadiaz-gly-betapy
45 245: phhs-25oxaz-gly-betadcphee45 245: phhs-25oxaz-gly-betadcphee
246: phhs-24thiaz-gly-betapy246: phhs-24thiaz-gly-betapy
247 : tolhs-ithiadiaz-bala-betamesu 248: bhs-25oxaz-nmgly-betal3bendi247: tolhs-ithiadiaz-bala-betamesu 248: bhs-25oxaz-nmgly-betal3bendi
249: phhs-24thiaz-gly-psdapch249: phhs-24thiaz-gly-psdapch
250: phhs-25oxaz-bala-asppha250: phhs-25oxaz-bala-asppha
251: phhs-25oxaz-bala-beta3quin 5 252: phhs-25methiaz-gly-beta3quin251: phhs-25oxaz-bala-beta3quin 5 252: phhs-25methiaz-gly-beta3quin
253 : phhs-me25oxaz-bala-betadcph253: phhs-me25oxaz-bala-betadcph
254: phhs-me24thiaz-ala-psdap254: phhs-me24thiaz-ala-psdap
255: ibhs-24thioph-gly-betapych255: ibhs-24thioph-gly-betapych
256: phhs-ithiadiaz-bala-betaibph256: phhs-ithiadiaz-bala-betaibph
257: bhs-25oxaz-bala-betaftrif257: bras-25oxaz-bala-betaftrif
10 258: bhs-24thiaz-bala-betahc10 258: bras-24thiaz-bala-betahc
259: 2py-me24thioph-leu-psdap259: 2py-me24thioph-leu-psdap
260: phhs-24thioph-gly-betahc260: phhs-24thioph-gly-betahc
261: dhim-26py-gly-betaheph261: dhim-26py-gly-betaheph
262 : phhs-oxadiaz-bala-betaphethio 15 263: bhs-42nmeim-gly-betahni262: phhs-oxadiaz-bala-betaphethio 15 263: bhs-42nmeim-gly-betahni
264: tolhs-nme35pyr-bala-betahb264: tolhs-nme35pyr-bala-betahb
265: ibhs-nme35pyr-gly-betathiobe265: ibhs-nme35pyr-gly-betathiobe
266: tolhs-25oxaz-gly-betapytb266: tolhs-25oxaz-gly-betapytb
267 : 2py-me24oxaz-ala-beta34meoph 2o 268: ibhs-ithiadiaz-gly-betahph267: 2py-me24oxaz-ala-beta34meoph 2o 268: ibhs-ithiadiaz-gly-betahph
269: bhs-25methiaz-ala-betal3bendi269: bhs-25methiaz-ala-betal3bendi
270: gua-26py-gly-beta3quin270: gua-26py-gly-beta3quin
271: phhs-ithiadiaz-gly-betathiobe271: phhs-ithiadiaz-gly-betathiobe
272: bhs-oxadiaz-gly-betabpy272: bhs-oxadiaz-gly-betabpy
273: ibhs-25thiaz-bala-psdapch273: ibhs-25thiaz-bala-psdapch
25 274: phhs-ithiadiaz-gly-betacph25 274: phhs-ithiadiaz-gly-betacph
275: phhs-24thioph-gly-betabthioph275: phhs-24thioph-gly-betabthioph
276: gua-24thiaz-gly-betamesu276: gua-24thiaz-gly-betamesu
277: tolhs-24thiaz-gly-betambiph277: tolhs-24thiaz-gly-betambiph
278: bhs-me24oxaz-leu-betaph 30 279: 2pmhs-25methiaz-gly-betabpy278: bhs-me24oxaz-leu-betaph 30 279: 2 pmhs-25methiaz-gly-betabpy
280 : bhs-ithiadiaz-bala-betathiobe280: bras-ithiadiaz-bala-betathiobe
281: tolhs-25methiaz-bala-betafphe281: tolhs-25methiaz-bala-betafphe
282: tolhs-24thiaz-bala-betahni282: tolhs-24thiaz-bala-betahni
283: ibhs-25thiaz-gly-zdap 35 284: bhs-25thiaz-ala-betaanaphth283: ibhs-25thiaz-gly-zdap 35 284: bhs-25thiaz-ala-betaanaphth
285: ibhs-ithiadiaz-bala-betaphethio285: ibhs-ithiadiaz-bala-betaphethio
286: ibhs-25oxaz-gly-betaheph286: ibhs-25oxaz-gly-betaheph
287: 2py-me25thioph-leu-zdap287: 2py-me25thioph-leu-zdap
288: phhs-me24thiaz-bala-betaph288: phhs-me24thiaz-bala-betaph
289: bim-me25thioph-bala-betapy289: bim-me25thioph-bala-betapy
40 290: 2py-25thiaz-bala-betapy40 290: 2py-25thiaz-bala-betapy
291: phhs-25thiaz-bala-betatbuph291: phhs-25thiaz-bala-betatbuph
292 : bhs-24thioph-ala-betal3bendi292: bhs-24thioph-ala-betal3bendi
293 : tolhs-25methiaz-bala-betathiobe293: tolhs-25methiaz-bala-betathiobe
294: phhs-25thiaz-bala-betal3bendi 45 295: bim-nme35pyr-leu-psdap294: phhs-25thiaz-bala-betal3bendi 45 295: bim-nme35pyr-leu-psdap
296: phhs-25methiaz-gly-betatos296: phhs-25methiaz-gly-betatos
297: tolhs-nme35pyr-bala-betaibph 298: phhs-25oxaz-bala-betadcphee297: tolhs-nme35pyr-bala-betaibph 298: phhs-25oxaz-bala-betadcphee
299: hs-24thioph-bala-betapy299: hs-24thioph-bala-betapy
300: bim-42nmeim-gly-psdap300: bim-42nmeim-gly-psdap
301: ibhs-nme35pyr-bala-betambiph301: ibhs-nme35pyr-bala-betambiph
5 302: bhs-nme35pyr-bala-betahdcph5 302: bhs-nme35pyr-bala-betahdcph
303 : tolhs-ithiadiaz-bala-beta34meoph303: tolhs-ithiadiaz-bala-beta34meoph
304: bhs-25methiaz-ala-betahph304: bhs-25methiaz-ala-betahph
305: bim-53pyrazo-bala-psdap305: bim-53pyrazo-bala-psdap
306: 2pmhs-25thiaz-gly-betahb306: 2 pmhs-25thiaz-gly-betahb
307: 2py-me24thiaz-leu-betadcph 10307: 2py-me24thiaz-leu-betadcph 10
308: gua-24thιaz-gly-betahmph308: gua-24thιaz-gly-betahmph
309: ibhs-nme35pyr-gly-betaimid309: ibhs-nme35pyr-gly-betaimid
310: phhs-24thiaz-bala-zdaptb310: phhs-24thiaz-bala-zdaptb
311: tolhs-24thiaz-gly-betaph311: tolhs-24thiaz-gly-betaph
312: gua-24thiaz-gly-betahdcph 15 313: bhs-25methiaz-bala-betapyee312: gua-24thiaz-gly-betahdcph 15 313: bhs-25methiaz-bala-betapyee
314: 2py-42nmeim-gly-csdap314: 2py-42nmeim-gly-csdap
315: bhs-25oxaz-ala-betadito315: bras-25oxaz-ala-betadito
316: bhs-nme35pyr-gly-betafu3316: bhs-nme35pyr-gly-betafu3
317: ibhs-25oxaz-bala-betahdbph 2o 318: phhs-nme35pyr-gly-betabmph317: ibhs-25oxaz-bala-betahdbph 2o 318: phhs-nme35pyr-gly-betabmph
319: phhs-ithiadiaz-bala-betapych319: phhs-ithiadiaz-bala-betapych
320: bim-24thiaz-leu-psdap320: bim-24thiaz-leu-psdap
321: bhs-oxadiaz-bala-betadcphee321: bras-oxadiaz-bala-betadcphee
322: tolhs-ithiadiaz-bala-betaol322: tolhs-ithiadiaz-bala-betaol
323: gua-42pym-gly-betabediox323: gua-42pym-gly-betabediox
25 324: bim-24thiaz-gly-asppha25 324: bim-24thiaz-gly-asppha
325: tolhs-24thiaz-gly-betahmofu325: tolhs-24thiaz-gly-betahmofu
326: ibhs-oxadiaz-gly-beta23meoph326: ibhs-oxadiaz-gly-beta23meoph
327: phhs-me24thioph-ala-zdap327: phhs-me24thioph-ala-zdap
328: phhs-me24oxaz-gly-betaph328: phhs-me24oxaz-gly-betaph
30 329: bhs-25oxaz-nmgly-beta23meoph30 329: bhs-25oxaz-nmgly-beta23meoph
330: tolhs-ithiadiaz-bala-betadbph 331: bhs-24im-bala-zdap330: tolhs-ithiadiaz-bala-betadbph 331: bhs-24im-bala-zdap
332: phhs-oxadiaz-gly-busu2be332: phhs-oxadiaz-gly-busu2be
333 : ibhs-25methiaz-bala-betathio3333: ibhs-25methiaz-bala-betathio3
35 334: tolhs-24thiaz-bala-betabdimo35 334: tolhs-24thiaz-bala-betabdimo
335: bhs-25oxaz-bala-betaipr335: bras-25oxaz-bala-betaipr
336: 2py-me25thiaz-ala-betaph336: 2py-me25thiaz-ala-betaph
337: bhs-25methiaz-gly-betapyr337: bhs-25methiaz-gly-betapyr
338: tolhs-25oxaz-bala-betainyl338: tolhs-25oxaz-bala-betainyl
339: ibhs-25oxaz-gly-betaoxaz339: ibhs-25oxaz-gly-betaoxaz
40 340: tolhs-25thiaz-gly-betapyr40 340: tolhs-25thiaz-gly-betapyr
341: phhs-25methiaz-bala-betacbph341: phhs-25methiaz-bala-betacbph
342: bhs-24thioph-gly-betadmoph342: bhs-24thioph-gly-betadmoph
343: tolhs-oxadiaz-bala-aspbzla343: tolhs-oxadiaz-bala-aspbzla
344: dhim-25thioph-gly-zdap344: dhim-25thioph-gly-zdap
45 345: phhs-25oxaz-bala-betafph45 345: phhs-25oxaz-bala-betafph
346: tolhs-25methiaz-bala-betaoxaz346: tolhs-25methiaz-bala-betaoxaz
347 : ibhs-nme35pyr-bala-aspbzla 348: bhs-oxadiaz-bala-betahcbph347: ibhs-nme35pyr-bala-aspbzla 348: bras-oxadiaz-bala-betahcbph
349: phhs-oxadiaz-gly-betameph349: phhs-oxadiaz-gly-betameph
350: phhs-me24thioph-leu-betadcph350: phhs-me24thioph-leu-betadcph
351: ibhs-nme35pyr-gly-busu2be 5 352: dhim-24oxaz-ala-zdap351: ibhs-nme35pyr-gly-busu2be 5 352: dhim-24oxaz-ala-zdap
353: 2py-me24oxaz-ala-betaph353: 2py-me24oxaz-ala-betaph
354: phhs-ithiadiaz-gly-betampy354: phhs-ithiadiaz-gly-betampy
355: bhs-ithiadiaz-gly-psdap355: bhs-ithiadiaz-gly-psdap
356: ibhs-24thioph-gly-aspbzla356: ibhs-24thioph-gly-aspbzla
357: bim-ithiadiaz-leu-psdap357: bim-ithiadiaz-leu-psdap
10 358: dhim-24thiaz-gly-betahdcph10,358: dhim-24thiaz-gly-betahdcph
359: bim-me25oxaz-ala-betadcph359: bim-me25oxaz-ala-betadcph
360: gua-24thiaz-gly-betaoxope360: gua-24thiaz-gly-betaoxope
361: bim-nme35pyr-ala-betadcph361: bim-nme35pyr-ala-betadcph
362 : phhs-24thioph-bala-betabthioph 15 363: 2py-25methiaz-bala-aspbzla362: phhs-24thioph-bala-betabthioph 15 363: 2py-25methiaz-bala-aspbzla
364: tolhs-nme35pyr-gly-betaet364: tolhs-nme35pyr-gly-betaet
365 : bhs-52thiaz-gly-zdap365: bhs-52thiaz-gly-zdap
366: ibhs-oxadiaz-gly-betafbph366: ibhs-oxadiaz-gly-betafbph
367: bhs-24thiaz-gly-betafu3 20 368: bim-25thiaz-gly-betapy367: bhs-24thiaz-gly-betafu3 20 368: bim-25thiaz-gly-betapy
369: bhs-24thiaz-gly-betah35dc369: bhs-24thiaz-gly-betah35dc
370: tolhs-24thiaz-bala-aspibua370: tolhs-24thiaz-bala-aspibua
371: tolhs-24thioph-bala-betadhbfu371: tolhs-24thioph-bala-betadhbfu
372: tolhs-24thioph-gly-psdapee372: tolhs-24thioph-gly-psdapee
373: ibhs-25thiaz-bala-betapym373: ibhs-25thiaz-bala-betapym
25 374: bhs-52thiaz-ala-betainyl25,374: bhs-52thiaz-ala-betainyl
375: ibhs-25oxaz-bala-betadtrif375: ibhs-25oxaz-bala-betadtrif
376 : ibhs-ithiadiaz-gly-betamethioph376: ibhs-ithiadiaz-gly-betamethioph
377: tolhs-25methiaz-gly-betabpy377: tolhs-25methiaz-gly-betabpy
378: ibhs-25methiaz-bala-beta35dbph 30 379: ibhs-25oxaz-bala-beta35dbph378: ibhs-25methiaz-bala-beta35dbph 30 379: ibhs-25oxaz-bala-beta35dbph
380: bhs-me25thiaz-bala-zdap380: bhs-me25thiaz-bala-zdap
381: bhs-25oxaz-gly-asppha381: bhs-25oxaz-gly-asppha
382 : bhs-25methiaz-bala-betaphethio382: bhs-25methiaz-bala-betaphethio
383: bim-42oxaz-bala-betadcph 35 384: ibhs-24thiaz-bala-beta3quin383: bim-42oxaz-bala-betadcph 35 384: ibhs-24thiaz-bala-beta3quin
385: bhs-25methiaz-gly-betadcphtb385: bhs-25methiaz-gly-betadcphtb
386: bhs-ithiadiaz-gly-betadcphtb386: bhs-ithiadiaz-gly-betadcphtb
387 : ibhs-25oxaz-bala-betafph387: ibhs-25oxaz-bala-betafph
388: tolhs-24thioph-gly-betahmo388: tolhs-24thioph-gly-betahmo
389: bhs-24thioph-bala-betafbph389: bhs-24thioph-bala-betafbph
40 390 : phhs-24thiaz-bala-betal3bendi40 390: phhs-24thiaz-bala-betal3bendi
391: 2py-24oxaz-bala-zdap391: 2py-24oxaz-bala-zdap
392: phhs-nme35pyr-gly-betadbph392: phhs-nme35pyr-gly-betadbph
393: bhs-25methiaz-bala-betacph393: bras-25methiaz-bala-betacph
394 : tolhs-25oxaz-gly-betamethioph 45 395: ibhs-24thiaz-bala-betambiph394: tolhs-25oxaz-gly-betamethioph 45 395: ibhs-24thiaz-bala-betambiph
396: bhs-24thioph-nmgly-ibsdap396: bhs-24thioph-nmgly-ibsdap
397: phhs-nme35pyr-bala-betahmph 398: dhim-52thiaz-ala-betameph397: phhs-nme35pyr-bala-betahmph 398: dhim-52thiaz-ala-betameph
399: tolhs-oxadiaz-gly-beta3quin399: tolhs-oxadiaz-gly-beta3quin
400: bhs-25methiaz-nmgly-betaoxaz400: bhs-25methiaz-nmgly-betaoxaz
401: bhs-oxadiaz-ala-betafphe 5 402: phhs-25methiaz-gly-betafluo401: bhs-oxadiaz-ala-betafphe 5 402: phhs-25methiaz-gly-betafluo
403: bhs-25oxaz-leu-betadcph403: bras-25oxaz-leu-betadcph
404: tolhs-25methiaz-gly-betaipr404: tolhs-25methiaz-gly-betaipr
405: dhim-26py-gly-betahcbph405: dhim-26py-gly-betahcbph
406: bhs-25methiaz-gly-zdapee406: bhs-25methiaz-gly-zdapee
407: 2pmhs-24thioph-gly-betahbcph407: 2 pmhs-24thioph-gly-betahbcph
10 408: phhs-ithiadiaz-bala-betahc10 408: phhs-ithiadiaz-bala-betahc
409: tolhs-24thiaz-gly-betaipr409: tolhs-24thiaz-gly-betaipr
410: ibhs-nme35pyr-bala-betainyl410: ibhs-nme35pyr-bala-betainyl
411: bhs-42pym-ala-zdap411: bhs-42pym-ala-zdap
412: bhs-25oxaz-bala-betaphethio 15 413: impy-25thiaz-gly-betahmofu412: bras-25oxaz-bala-betaphethio 15 413: impy-25thiaz-gly-betahmofu
414 : bhs-25thiaz-bala-betadmph414: bras-25thiaz-bala-betadmph
415: tolhs-me25thioph-ala-betaph415: tolhs-me25thioph-ala-betaph
416: bim-24thioph-gly-aspbzla416: bim-24thioph-gly-aspbzla
417: tolhs-nme35pyr-gly-betaheph 20 418: phhs-25oxaz-bala-betatrif417: tolhs-nme35pyr-gly-betaheph 20 418: phhs-25oxaz-bala-betatrif
419: tolhs-24thioph-gly-betathiome419: tolhs-24thioph-gly-betathioma
420: ibhs-nme35pyr-gly-betathioph420: ibhs-nme35pyr-gly-betathioph
421: ibhs-25methiaz-gly-betambiph421: ibhs-25methiaz-gly-betambiph
422: bhs-25oxaz-bala-betacthioph422: bras-25oxaz-bala-betacthioph
423: ibhs-24thiaz-gly-csdap423: ibhs-24thiaz-gly-csdap
25 424: 2py-ithiadiaz-gly-asppha25 424: 2py-ithiadiaz-gly-asppha
425: tolhs-25thiaz-gly-betabdimo425: tolhs-25thiaz-gly-betabdimo
426: tolhs-25thiaz-gly-zdap426: tolhs-25thiaz-gly-zdap
427 : tolhs-25methiaz-bala-betadmoph427: tolhs-25methiaz-bala-betadmoph
428: tolhs-25thiaz-gly-betabediox 30 429: phhs-25methiaz-gly-betadbph428: tolhs-25thiaz-gly-betabediox 30 429: phhs-25methiaz-gly-betadbph
430 : ibhs-oxadiaz-gly-betahni 431: tolhs-24thiaz-bala-betahdbph 432: phhs-25oxaz-gly-betadmoph 433 : phhs-24thiaz-gly-betaomebendi430: ibhs-oxadiaz-gly-betahni 431: tolhs-24thiaz-bala-betahdbph 432: phhs-25oxaz-gly-betadmoph 433: phhs-24thiaz-gly-betaomebendi
35 434: tolhs-ithiadiaz-bala-zdapee35 434: tolhs-ithiadiaz-bala-zdapee
435: tolhs-25oxaz-gly-betathiobe435: tolhs-25oxaz-gly-betathiobe
436: phhs-25oxaz-bala-betaibph436: phhs-25oxaz-bala-betaibph
437: 2py-25oxaz-leu-zdap437: 2py-25oxaz-leu-zdap
438: bhs-24oxaz-leu-betadcph438: bras-24oxaz-leu-betadcph
439 : bhs-nme35pyr-ala-psdap439: bhs-nme35pyr-ala-psdap
40 440: phhs-oxadiaz-bala-betabediox40 440: phhs-oxadiaz-bala-betabediox
441 : tolhs-oxadiaz-bala-betapbiph441: tolhs-oxadiaz-bala-betapbiph
442 : 2py-ithiadiaz-bala-aspaba442: 2py-ithiadiaz-bala-aspaba
443: tolhs-24thiaz-bala-psdaptb443: tolhs-24thiaz-bala-psdaptb
444: bhs-24thiaz-gly-busu2be 45 445: ibhs-25thiaz-gly-betaoxaz444: bhs-24thiaz-gly-busu2be 45 445: ibhs-25thiaz-gly-betaoxaz
446 : bhs-24thioph-gly-betaphethio446: bhs-24thioph-gly-betaphethio
447 : bim-35thioph-bala-betapy 448: dimethpym-25methiaz-gly-betameph447: bim-35thioph-bala-betapy 448: dimethpym-25methiaz-gly-betameph
449: 2py-ithiadiaz-bala-zdap449: 2py-ithiadiaz-bala-zdap
450: bhs-25thiaz-nmgly-betabpy450: bhs-25thiaz-nmgly-betabpy
451: 2py-35fur-ala-betapy 5 452: phhs-25oxaz-gly-betamethioph451: 2py-35fur-ala-betapy 5 452: phhs-25oxaz-gly-betamethioph
453 : tolhs-me24thioph-bala-betapy453: tolhs-me24thioph-bala-betapy
454: tolhs-ithiadiaz-gly-betafu3454: tolhs-ithiadiaz-gly-betafu3
455: gua-26py-gly-betaimid455: gua-26py-gly-betaimide
456 : phhs-nme35pyr-bala-betaphethio456: phhs-nme35pyr-bala-betaphethio
457: bhs-25oxaz-gly-aspibua457: bhs-25oxaz-gly-aspibua
10 458: ibhs-oxadiaz-gly-betafph10 458: ibhs-oxadiaz-gly-betafph
459: ibhs-oxadiaz-gly-betafu3459: ibhs-oxadiaz-gly-betafu3
460: ibhs-24thiaz-bala-betahcbph460: ibhs-24thiaz-bala-betahcbph
461: tolhs-24thioph-gly-betafluo461: tolhs-24thioph-gly-betafluo
462: 2py-24thioph-leu-betapy 15 463: impy-25oxaz-gly-ibsdap462: 2py-24thioph-leu-betapy 15 463: impy-25oxaz-gly-ibsdap
464: phhs-nme35pyr-gly-aspbzla464: phhs-nme35pyr-gly-aspbzla
465: 4pmhs-42nmeim-bala-betadcph465: 4 pmhs-42nmeim-bala-betadcph
466: tolhs-me25thioph-leu-beta34meoph466: tolhs-me25thioph-leu-beta34meoph
467: phhs-oxadiaz-gly-betaoxaz 2o 468: tolhs-nme35pyr-gly-betamethioph467: phhs-oxadiaz-gly-betaoxaz 2o 468: tolhs-nme35pyr-gly-betamethioph
469: bhs-25thiaz-gly-betaheph469: bhs-25thiaz-gly-betaheph
470: phhs-nme35pyr-bala-betaoxaz470: phhs-nme35pyr-bala-betaoxaz
471: bhs-24thioph-nmgly-betacph471: bhs-24thioph-nmgly-betacph
472 : bim-me25oxaz-ala-beta34meoph472: bim-me25oxaz-ala-beta34meoph
473: bhs-25methiaz-gly-betacbph473: bhs-25methiaz-gly-betacbph
25 474: impy-25methiaz-gly-betahmofu25 474: impy-25methiaz-gly-betahmofu
475: dhim-35pyrazo-gly-betameph475: dhim-35pyrazo-gly-betameph
476: bim-35fur-ala-zdap476: bim-35fur-ala-zdap
477: phhs-25oxaz-gly-betahc477: phhs-25oxaz-gly-betahc
478: bhs-24thioph-bala-aspibua 30 479: 2py-24thiaz-gly-betacthioph478: bhs-24thioph-bala-aspibua 30 479: 2py-24thiaz-gly-betacthioph
480: bhs-oxadiaz-bala-suabu480: bras-oxadiaz-bala-suabu
481 : bhs-25methiaz-gly-aspaba481: bhs-25methiaz-gly-aspaba
482: tolhs-nme35pyr-gly-betaipr482: tolhs-nme35pyr-gly-betaipr
483: 2py-ithiadiaz-ala-psdap 35 484: ibhs-ithiadiaz-bala-betathiobe483: 2py-ithiadiaz-ala-psdap 35 484: ibhs-ithiadiaz-bala-betathiobe
485: bhs-nme35pyr-bala-betapyee485: bhs-nme35pyr-bala-betapyee
486 : tolhs-25methiaz-bala-betahc486: tolhs-25methiaz-bala-betahc
487: tolhs-25oxaz-gly-zdaptb487: tolhs-25oxaz-gly-zdaptb
488: bhs-24thioph-gly-beta23meoph488: bhs-24thioph-gly-beta23meoph
489 : tolhs-24thioph-bala-betaphethioa489: tolhs-24thioph-bala-betaphethioa
40 90: bhs-nme35pyr-bala-betahbcph40 90: bras-nme35pyr-bala-betahbcph
491: phhs-25oxaz-gly-betadbph491: phhs-25oxaz-gly-betadbph
492: bhs-25methiaz-bala-asppha492: bras-25methiaz-bala-asppha
493: ibhs-nme35pyr-gly-psdapch493: ibhs-nme35pyr-gly-psdapch
494: bhs-oxadiaz-bala-ibsdap 45 495: bhs-25methiaz-bala-betapy494: bhs-oxadiaz-bala-ibsdap 45 495: bhs-25methiaz-bala-betapy
496: ibhs-24thiaz-gly-betabdimo496: ibhs-24thiaz-gly-betabdimo
497: ibhs-24thiaz-bala-beta34dcph 498: phhs-oxadiaz-gly-betadcphch497: ibhs-24thiaz-bala-beta34dcph 498: phhs-oxadiaz-gly-betadcphch
499: bim-nme35pyr-gly-betadcph499: bim-nme35pyr-gly-betadcph
500: bhs-ithiadiaz-gly-betahc500: bhs-ithiadiaz-gly-betahc
501 : ibhs-ithiadiaz-bala-betathiome 5 502: bim-me24oxaz-leu-zdap501: ibhs-ithiadiaz-bala-betathiome 5 502: bim-me24oxaz-leu-zdap
503: bhs-25oxaz-gly-betadcphee503: bras-25oxaz-gly-betadcphee
504: bim-25fur-leu-psdap504: bim-25fur-leu-psdap
505 : tolhs-oxadiaz-bala-betatbuph505: tolhs-oxadiaz-bala-betatbuph
506: gua-42pym-gly-betadbph506: gua-42pym-gly-betadbph
507: ibhs-24thioph-gly-aspaba507: ibhs-24thioph-gly-aspaba
10 508: ibhs-25methiaz-gly-beta34dcph10 508: ibhs-25methiaz-gly-beta34dcph
509 : tolhs-ithiadiaz-bala-betahbcph509: tolhs-ithiadiaz-bala-betahbcph
510: bhs-oxadiaz-nmgly-betaoxaz510: bhs-oxadiaz-nmgly-betaoxaz
511: tolhs-25thiaz-bala-betadbph511: tolhs-25thiaz-bala-betadbph
512 : bhs-oxadiaz-bala-betaomebendi 15 513: thpym-24thiaz-gly-betameph512: bhs-oxadiaz-bala-betaomebendi 15 513: thpym-24thiaz-gly-betameph
514: bhs-ithiadiaz-bala-beta35dbph514: bhs-ithiadiaz-bala-beta35dbph
515: 2pmhs-25thiaz-gly-betadtrif515: 2 pmhs-25thiaz-gly-betadtrif
516: ibhs-ithiadiaz-bala-psdapch516: ibhs-ithiadiaz-bala-psdapch
517 : phhs-24thioph-bala-betaanaphth 20 518: bhs-25thiaz-bala-betaet517: phhs-24thioph-bala-betaanaphth 20 518: bhs-25thiaz-bala-betaet
519 : ibhs-ithiadiaz-bala-betahdcph519: ibhs-ithiadiaz-bala-betahdcph
520: bhs-42oxaz-ala-zdap520: bhs-42oxaz-ala-zdap
521: tolhs-24thioph-gly-busu2be521: tolhs-24thioph-gly-busu2be
522: bhs-ithiadiaz-gly-betaftrif522: bhs-ithiadiaz-gly-betaftrif
523: tolhs-nme35pyr-gly-betadhbfu523: tolhs-nme35pyr-gly-betadhbfu
25 524: bhs-24thiaz-gly-aspibua25,524: bhs-24thiaz-gly-aspibua
525: bhs-24thioph-gly-betapy525: bhs-24thioph-gly-betapy
526: ibhs-25oxaz-gly-aspbzla526: ibhs-25oxaz-gly-aspbzla
527: tolhs-24thioph-bala-betadbph527: tolhs-24thioph-bala-betadbph
528: phhs-25methiaz-gly-betabenfu 30 529: bhs-nme35pyr-ala-betadito528: phhs-25methiaz-gly-betabenfu 30 529: bhs-nme35pyr-ala-betadito
530 : phhs-me25thiaz-ala-beta34meoph 531 : ibhs-25methiaz-bala-betamethi 532: ibhs-25oxaz-gly-betahmofu 533: bhs-24thioph-gly-zdapch530: phhs-me25thiaz-ala-beta34meoph 531: ibhs-25methiaz-bala-betamethi 532: ibhs-25oxaz-gly-betahmofu 533: bhs-24thioph-gly-zdapch
35 534: phhs-24thioph-bala-betah35dc35 534: phhs-24thioph-bala-betah35dc
535 : ibhs-24thioph-bala-betahcbph535: ibhs-24thioph-bala-betahcbph
536 : ibhs-ithiadiaz-bala-betahph536: ibhs-ithiadiaz-bala-betahph
537: bhs-ithiadiaz-bala-asppha537: bhs-ithiadiaz-bala-asppha
538: dhim-25thioph-gly-betameph538: dhim-25thioph-gly-betameph
539 : tolhs-ithiadiaz-gly-betadcphee539: tolhs-ithiadiaz-gly-betadcphee
40 540: phhs-oxadiaz-bala-betatbuph40 540: phhs-oxadiaz-bala-betatbuph
541: bhs-25thiaz-gly-betamethi541: bhs-25thiaz-gly-betamethi
542: bhs-ithiadiaz-gly-betahbcph542: bhs-ithiadiaz-gly-betahbcph
543 : tolhs-25oxaz-bala-betadcphtb543: tolhs-25oxaz-bala-betadcphtb
544: phhs-24thiaz-gly-betadhbfu 45 545: ibhs-25oxaz-gly-psdap544: phhs-24thiaz-gly-betadhbfu 45 545: ibhs-25oxaz-gly-psdap
546 : ibhs-25methiaz-bala-betatrif546: ibhs-25methiaz-bala-betatrif
547 : bhs-ithiadiaz-bala-beta23meoph 548: phhs-25thiaz-gly-betahmofu547: bhs-ithiadiaz-bala-beta23meoph 548: phhs-25thiaz-gly-betahmofu
549: bhs-24thioph-gly-betamethi549: bhs-24thioph-gly-betamethi
550: ibhs-25oxaz-gly-betadito550: ibhs-25oxaz-gly-betadito
551 : bhs-25methiaz-gly-betadcph 5 552: bhs-me24thioph-ala-psdap551: bhs-25methiaz-gly-betadcph 5 552: bhs-me24thioph-ala-psdap
553: tolhs-25thiaz-gly-betahni553: tolhs-25thiaz-gly-betahni
554: ibhs-24thioph-gly-betafu3554: ibhs-24thioph-gly-betafu3
555: phhs-24thiaz-gly-betahni555: phhs-24thiaz-gly-betahni
556: 2py-24thioph-gly-aspbzla556: 2py-24thioph-gly-aspbzla
557: ibhs-nme35pyr-gly-betaibph557: ibhs-nme35pyr-gly-betaibph
1010
558: tolhs-25methJaz-gly-psdapch558: tolhs-25methJaz-gly-psdapch
559: bhs-ithiadiaz-gly-betaet559: bhs-ithiadiaz-gly-betet
560: bhs-nme35pyr-ala-beta34meoph560: bhs-nme35pyr-ala-beta34meoph
561: phhs-oxadiaz-gly-betapyr561: phhs-oxadiaz-gly-betapyr
562: ibhs-25oxaz-gly-zdapch 15 563: bhs-24oxaz-ala-betainyl562: ibhs-25oxaz-gly-zdapch 15 563: bhs-24oxaz-ala-betainyl
564: ibhs-nme35pyr-gly-betahmo564: ibhs-nme35pyr-gly-betahmo
565: bhs-25thiaz-nmgly-beta34dcph565: bhs-25thiaz-nmgly-beta34dcph
566 : bhs-nme35pyr-bala-betaomebendi566: bhs-nme35pyr-bala-betaomebendi
567: tolhs-25oxaz-gly-betaph 20 568: bhs-24thiaz-nmgly-betahph567: tolhs-25oxaz-gly-betaph 20 568: bhs-24thiaz-nmgly-betahph
569: bhs-nme35pyr-leu-psdap569: bhs-nme35pyr-leu-psdap
570: ibhs-24thioph-gly-betahni570: ibhs-24thioph-gly-betahni
571: ibhs-25oxaz-gly-betaftrif571: ibhs-25oxaz-gly-betaftrif
572: phhs-me24thiaz-leu-zdap572: phhs-me24thiaz-leu-zdap
573: ibhs-24thiaz-gly-betathiobe573: ibhs-24thiaz-gly-betathiobe
2525
574: phhs-25oxaz-bala-betabediox574: phhs-25oxaz-bala-betabediox
575: phhs-ithiadiaz-gly-betameph575: phhs-ithiadiaz-gly-betameph
576: tolhs-ithiadiaz-gly-psdaptb576: tolhs-ithiadiaz-gly-psdaptb
577: 2py-me25oxaz-leu-zdap577: 2py-me25oxaz-leu-zdap
578: dhim-24oxaz-gly-zdap 30 579: tolhs-oxadiaz-gly-betapbiph578: dhim-24oxaz-gly-zdap 30 579: tolhs-oxadiaz-gly-betapbiph
580: tolhs-24 hioph-gly-betadcphch580: tolhs-24 hioph-gly-betadcphch
581: bhs-ithiadiaz-bala-psdapee581: bhs-ithiadiaz-bala-psdapee
582: imhs-25methiaz-gly-zdap582: imhs-25methiaz-gly-zdap
583: bhs-25oxaz-gly-betabnaphth 35 584: bhs-24thiaz-gly-betaftrif583: bhs-25oxaz-gly-betabnaphth 35 584: bhs-24thiaz-gly-betaftrif
585: phhs-25methiaz-gly-betahmofu585: phhs-25methiaz-gly-betahmofu
586: phhs-ithiadiaz-bala-betamethi586: phhs-ithiadiaz-bala-betamethi
587: bhs-ithiadiaz-gly-betabdimo587: bhs-ithiadiaz-gly-betabdimo
588: dhim-42pym-gly-betainyl588: dhim-42pym-gly-betainyl
589: bhs-25thioph-bala-betadcph589: bhs-25thioph-bala-betadcph
40 590: 2py-thiadiaz-leu-betapy40 590: 2py-thiadiaz-leu-betapy
591: tolhs-25oxaz-bala-betabmph591: tolhs-25oxaz-bala-betabmph
592: phhs-25oxaz-gly-betadito592: phhs-25oxaz-gly-betadito
593: bim-ithiadiaz-gly-psdap593: bim-ithiadiaz-gly-psdap
594: phhs-24thioph-gly-betaibph 45 595: tolhs-25oxaz-gly-psdapee594: phhs-24thioph-gly-betaibph 45 595: tolhs-25oxaz-gly-psdapee
596: ibhs-25methiaz-gly-betamesu596: ibhs-25methiaz-gly-betamesu
597: bhs-oxadiaz-bala-aspaba 598: bhs-oxadiaz-bala-betapym597: bras-oxadiaz-bala-aspaba 598: bras-oxadiaz-bala-betapym
599: phhs-24thioph-gly-betafu3599: phhs-24thioph-gly-betafu3
600 : tolhs-24thioph-gly-betaphethioa600: tolhs-24thioph-gly-betaphethioa
601: ibhs-25oxaz-bala-betafphe 5 602: tolhs-25oxaz-gly-betacbph601: ibhs-25oxaz-bala-betafphe 5 602: tolhs-25oxaz-gly-betacbph
603 : ibhs-25methiaz-bala-betaipro603: ibhs-25methiaz-bala-betaipro
604: bhs-nme35pyr-gly-betaipro604: bhs-nme35pyr-gly-betaipro
605: tolhs-24thioph-bala-betahmph605: tolhs-24thioph-bala-betahmph
606: tolhs-25methiaz-bala-betadbph606: tolhs-25methiaz-bala-betadbph
607: bhs-25methiaz-gly-betaamibe607: bhs-25methiaz-gly-betaamibe
1010
608: impy-24thiaz-gly-betabediox608: impy-24thiaz-gly-betabediox
609: ibhs-oxadiaz-gly-betapym609: ibhs-oxadiaz-gly-betapym
610: 2py-25methiaz-ala-betapy610: 2py-25methiaz-ala-betapy
611 : tolhs-nme35pyr-bala-betabnaphth611: tolhs-nme35pyr-bala-betabnaphth
612: phhs-24thioph-gly-beta4bph 15 613: ibhs-ithiadiaz-bala-betah35dc612: phhs-24thioph-gly-beta4bph 15 613: ibhs-ithiadiaz-bala-betah35dc
614 : bhs-oxadiaz-gly-betaomebendi614: bhs-oxadiaz-gly-betaomebendi
615: tolhs-25methiaz-gly-betafph615: tolhs-25methiaz-gly-betafph
616: phhs-25oxaz-bala-betadcphtb616: phhs-25oxaz-bala-betadcphtb
617 : ibhs-ithiadiaz-gly-beta35dbph 20 618: 2py-25oxaz-bala-betadhbfu617: ibhs-ithiadiaz-gly-beta35dbph 20 618: 2py-25oxaz-bala-betadhbfu
619: bhs-25oxaz-gly-betatrif619: bras-25oxaz-gly-betatrif
620: ibhs-25thiaz-gly-zdapch620: ibhs-25thiaz-gly-zdapch
621: bhs-oxadiaz-gly-betadmoph621: bhs-oxadiaz-gly-betadmoph
622 : phhs-nme35pyr-bala-betacthioph622: phhs-nme35pyr-bala-betacthioph
623: phhs-25thiaz-bala-betaoxaz623: phhs-25thiaz-bala-betaoxaz
25 624 : bim-me25oxaz-gly-psdap25 624: bim-me25oxaz-gly-psdap
625: bhs-25methiaz-ala-betapy625: bhs-25methiaz-ala-betapy
626 : ibhs-24thioph-bala-betathioph626: ibhs-24thioph-bala-betathioph
627: phhs-25methiaz-gly-suabu627: phhs-25methiaz-gly-suabu
628: phhs-ithiadiaz-bala-betacph 30 629: phhs-25methiaz-gly-betadmoph628: phhs-ithiadiaz-bala-betacph 30 629: phhs-25methiaz-gly-betadmoph
630: phhs-ithiadiaz-bala-zdapch 631: phhs-24thiaz-gly-betabediox 632: bhs-nme35pyr-bala-betatos 633: tolhs-25oxaz-bala-betaipr630: phhs-ithiadiaz-bala-zdapch 631: phhs-24thiaz-gly-betabediox 632: bhs-nme35pyr-bala-betatos 633: tolhs-25oxaz-bala-betaipr
35 634: bhs-24thioph-gly-betapytb35 634: bhs-24thioph-gly-betapytb
635: bhs-25methiaz-leu-betapy635: bhs-25methiaz-leu-betapy
636: 4pmhs-24thiaz-gly-betapy636: 4 pmhs-24thiaz-gly-betapy
637: tolhs-oxadiaz-bala-betapytb637: tolhs-oxadiaz-bala-betapytb
638 : tolhs-oxadiaz-gly-beta34meoph638: tolhs-oxadiaz-gly-beta34meoph
639 : bhs-25oχaz-bala-betatbuph639: bhs-25oχaz-bala-betatbuph
40 640: ibhs-25oxaz-gly-suabu40 640: ibhs-25oxaz-gly-suabu
641: phhs-25methiaz-gly-psdaptb641: phhs-25methiaz-gly-psdaptb
642: tolhs-25oxaz-bala-betahph642: tolhs-25oxaz-bala-betahph
643: ibhs-nme35pyr-gly-betabmph643: ibhs-nme35pyr-gly-betabmph
644 : bhs-25oxaz-gly-betadmph 45 645: ibhs-25oxaz-bala-betabpy644: bhs-25oxaz-gly-betadmph 45 645: ibhs-25oxaz-bala-betabpy
646: pnhs-me24thioph-gly-betadcph646: pnhs-me24thioph-gly-betadcph
647 : tolhs-24thioph-bala-betathio3 648: ibhs-25methiaz-bala-psdap647: tolhs-24thioph-bala-betathio3 648: ibhs-25methiaz-bala-psdap
649: bim-25thiaz-gly-psdap649: bim-25thiaz-gly-psdap
650: ibhs-25methiaz-gly-betahbcph650: ibhs-25methiaz-gly-betahbcph
651: ibhs-ithiadiaz-gly-betacbph 5 652: ibhs-25methiaz-gly-betabthioph651: ibhs-ithiadiaz-gly-betacbph 5 652: ibhs-25methiaz-gly-betabthioph
653: bim-me24thioph-gly-betadcph653: bim-me24thioph-gly-betadcph
654: bhs-oxadiaz-bala-betatos654: bras-oxadiaz-bala-betatos
655: phhs-nme35pyr-gly-betabdimo655: phhs-nme35pyr-gly-betabdimo
656: gua-26py-gly-betahmofu656: gua-26py-gly-betahmofu
657: ibhs-24thioph-gly-psdaptb657: ibhs-24thioph-gly-psdaptb
10 658: phhs-25oxaz-bala-betainyl10 658: phhs-25oxaz-bala-betainyl
659: phhs-24thiaz-bala-betameph659: phhs-24thiaz-bala-betameph
660: bim-25thioph-bala-zdap660: bim-25thioph-bala-zdap
661: tolhs-25oxaz-bala-betahmo661: tolhs-25oxaz-bala-betahmo
662 : tolhs-ithiadiaz-gly-betacbph 15 663: tolhs-25methiaz-bala-beta34meoph662: tolhs-ithiadiaz-gly-betacbph 15 663: tolhs-25methiaz-bala-beta34meoph
664: bhs-24im-gly-betameph664: bhs-24im-gly-betameph
665: tolhs-oxadiaz-gly-betadcphee665: tolhs-oxadiaz-gly-betadcphee
666: phhs-25thiaz-gly-betadmph666: phhs-25thiaz-gly-betadmph
667: bhs-nme35pyr-ala-betadmoph 20 668: ibhs-24thiaz-gly-betafphe667: bhs-nme35pyr-ala-betadmoph 20 668: ibhs-24thiaz-gly-betafphe
669: cima-25oxaz-gly-betameph669: cima-25oxaz-gly-betameph
670 : phhs-25oxaz-gly-betatos670: phhs-25oxaz-gly-betatos
671 : phhs-25methiaz-bala-beta3quin671: phhs-25methiaz-bala-beta3quin
672: bim-24oxaz-ala-zdap672: bim-24oxaz-ala-zdap
673: ibhs-25methiaz-gly-csdap673: ibhs-25methiaz-gly-csdap
25 674: phhs-ithiadiaz-bala-betafph25 674: phhs-ithiadiaz-bala-betafph
675: dhim-52thiaz-gly-psdap675: dhim-52thiaz-gly-psdap
676: bhs-24thiaz-ala-zdap676: bhs-24thiaz-ala-zdap
677: ibhs-ithiadiaz-bala-aspibua677: ibhs-ithiadiaz-bala-aspibua
678 : ibhs-oxadiaz-bala-betahmofu 30 679: phhs-24thioph-bala-betaoxaz678: ibhs-oxadiaz-bala-betahmofu 30 679: phhs-24thioph-bala-betaoxaz
680: phhs-25oxaz-bala-busu2be680: phhs-25oxaz-bala-busu2be
681: tolhs-25oxaz-bala-ibsdap681: tolhs-25oxaz-bala-ibsdap
682: ibhs-24thioph-gly-betacph682: ibhs-24thioph-gly-betacph
683: bhs-35thioph-ala-betameph 35 684: 2py-25thioph-gly-betainyl683: bhs-35thioph-ala-betameph 35 684: 2py-25thioph-gly-betainyl
685: bim-nme35pyr-ala-betapy685: bim-nme35pyr-ala-betapy
686: 2py-25thiaz-bala-aspaba686: 2py-25thiaz-bala-aspaba
687: bhs-24thioph-gly-betabenfu687: bhs-24thioph-gly-betabenfu
688: phhs-nme35pyr-bala-betabph688: phhs-nme35pyr-bala-betabph
689: ibhs-oxadiaz-gly-betatos689: ibhs-oxadiaz-gly-betatos
40 690: phhs-ithiadiaz-gly-betamesu40 690: phhs-ithiadiaz-gly-betamesu
691: 2pmhs-25oxaz-bala-betabnaphth691: 2 pmhs-25oxaz-bala-betabnaphth
692 : tolhs-25methiaz-bala-busu2be692: tolhs-25methiaz-bala-busu2be
693: tolhs-25oxaz-gly-betapyr693: tolhs-25oxaz-gly-betapyr
694 : bhs-ithiadiaz-gly-beta34meoph 45 695: phhs-24thioph-bala-betampy694: bhs-ithiadiaz-gly-beta34meoph 45 695: phhs-24thioph-bala-betampy
696: tolhs-nme35pyr-gly-busu2be696: tolhs-nme35pyr-gly-busu2be
697: bhs-25oxaz-gly-psdap 698: phhs-25oxaz-gly-betaph697: bhs-25oxaz-gly-psdap 698: phhs-25oxaz-gly-betaph
699: phhs-me25oxaz-gly-zdap699: phhs-me25oxaz-gly-zdap
700: bhs-24thioph-gly-betahc700: bhs-24thioph-gly-betahc
701: ibhs-25thiaz-gly-beta23meoph 5 702: phhs-25methiaz-gly-betabnaphth701: ibhs-25thiaz-gly-beta23meoph 5 702: phhs-25methiaz-gly-betabnaphth
703: phhs-24thioph-gly-betabpy703: phhs-24thioph-gly-betabpy
704: tolhs-25oxaz-bala-betatbuph704: tolhs-25oxaz-bala-betatbuph
705: bhs- 4thiaz-gly-zdaptb705: bhs- 4thiaz-gly-zdaptb
706: gua-26py-gly-betaph706: gua-26py-gly-betaph
707: tolhs-me25thiaz-bala-betadcph707: tolhs-me25thiaz-bala-betadcph
10 708: phhs-24thiaz-bala-betabediox10 708: phhs-24thiaz-bala-betabediox
709: ibhs-25methiaz-gly-betathiobe709: ibhs-25methiaz-gly-betathiobe
710: phhs-24thiaz-gly-beta3quin710: phhs-24thiaz-gly-beta3quin
711: tolhs-25oxaz-gly-betadmph711: tolhs-25oxaz-gly-betadmph
712: dhpyrr-25thioph-gly-betadcph 15 713: phhs-ithiadiaz-gly-betahb712: dhpyrr-25thioph-gly-betadcph 15 713: phhs-ithiadiaz-gly-betahb
714: hts-42nmeim-gly-zdap714: hts-42nmeim-gly-zdap
715: dhim-24thiaz-gly-zdap715: dhim-24thiaz-gly-zdap
716: bhs-24thioph-ser-betapy716: bhs-24thioph-ser-betapy
717: 2py-25fur-bala-betadcph 20 718: bhs-42nmeim-bala-betaol717: 2py-25fur-bala-betadcph 20 718: bhs-42nmeim-bala-betaol
719: bhs-25methiaz-bala-betafphe719: bras-25methiaz-bala-betafphe
720: ibhs-25thiaz-bala-betaipr720: ibhs-25thiaz-bala-betaipr
721: 2py-24thiaz-bala-aspaba721: 2py-24thiaz-bala-aspaba
722: phhs-me25thiaz-ala-betadcph722: phhs-me25thiaz-ala-betadcph
723: phhs-oxadiaz-bala-betadmph723: phhs-oxadiaz-bala-betadmph
25 724 : tolhs-ithiadiaz-bala-betapych25 724: tolhs-ithiadiaz-bala-betapych
725: phhs-25oxaz-bala-betapych725: phhs-25oxaz-bala-betapych
726: tolhs-24thiaz-bala-betadbph726: tolhs-24thiaz-bala-betadbph
727: ibhs-25methiaz-gly-betabenfu727: ibhs-25methiaz-gly-betabenfu
728: bhs-25methiaz-gly-beta4bph 30 729: bhs-ithiadiaz-gly-betameph728: bhs-25methiaz-gly-beta4bph 30 729: bhs-ithiadiaz-gly-betameph
730: phhs-24thioph-bala-betabenfu 731: bhs-25methiaz-nmgly-ibsdap 732: bhs-oxadiaz-gly-betacbph 733: bhs-nme35pyr-gly-betaftrif730: phhs-24thioph-bala-betabenfu 731: bhs-25methiaz-nmgly-ibsdap 732: bhs-oxadiaz-gly-betacbph 733: bhs-nme35pyr-gly-betaftrif
35 734: phhs-25oxaz-gly-suabu35 734: phhs-25oxaz-gly-suabu
735: bhs-25methiaz-nmgly-betaanaphth735: bhs-25methiaz-nmgly-betaanaphth
736: bhs-ithiadiaz-bala-betadbph736: bhs-ithiadiaz-bala-betadbph
737: bim-me25oxaz-gly-betaph737: bim-me25oxaz-gly-betaph
738: phhs-24thioph-gly-betaoxaz738: phhs-24thioph-gly-betaoxaz
739: bhs-42oxaz-gly-zdap739: bhs-42oxaz-gly-zdap
40 740: bhs-24thiaz-nmgly-betahmph40 740: bhs-24thiaz-nmgly-betahmph
741: ibhs-ithiadiaz-bala-betapytb741: ibhs-ithiadiaz-bala-betapytb
742: bhs-25methiaz-nmgly-betafphe742: bhs-25methiaz-nmgly-betafphe
743: bhs-oχadiaz-ala-beta34meoph743: bhs-oχadiaz-ala-beta34meoph
744: bim-53pyrazo-ala-zdap 45 745: phhs-25methiaz-gly-betadcph744: bim-53pyrazo-ala-zdap 45 745: phhs-25methiaz-gly-betadcph
746: phhs-24thioph-gly-zdaptb746: phhs-24thioph-gly-zdaptb
747: hts-25oxaz-bala-betadcph 748: 2py-ithiadiaz-ala-betadcph 749: bim-nme35pyr-gly-betapy 750: phhs-oxadiaz-gly-betatrif747: hts-25oxaz-bala-betadcph 748: 2py-ithiadiaz-ala-betadcph 749: bim-nme35pyr-gly-betapy 750: phhs-oxadiaz-gly-betatrif
751: ibhs-24thiaz-bala-betabnaphth 5 752: 2py-25methiaz-gly-beta3quin 753: phhs-oxadiaz-bala-betapbiph751: ibhs-24thiaz-bala-betabnaphth 5 752: 2py-25methiaz-gly-beta3quin 753: phhs-oxadiaz-bala-betapbiph
754: tolhs-25thiaz-gly-betatrif754: tolhs-25thiaz-gly-betatrif
755: bim-53pyrazo-gly-betapy755: bim-53pyrazo-gly-betapy
756 : bhs-ithiadiaz-nmgly-betabnaphth756: bhs-ithiadiaz-nmgly-betabnaphth
757: phhs-25thiaz-gly-betadtrif757: phhs-25thiaz-gly-beta trif
10 758: phhs-nme35pyr-gly-psdapch10 758: phhs-nme35pyr-gly-psdapch
759 : tolhs-25thiaz-bala-betaomebendi759: tolhs-25thiaz-bala-betaomebendi
760: phhs-24thiaz-gly-betaoxope760: phhs-24thiaz-gly-betaoxope
761: ibhs-oxadiaz-gly-betathio3761: ibhs-oxadiaz-gly-betathio3
762: phhs-oxadiaz-gly-betaph 15 763: phhs-oxadiaz-bala-betabph762: phhs-oxadiaz-gly-betaph 15 763: phhs-oxadiaz-bala-betabph
764: bim-me25thiaz-bala-betaph764: bim-me25thiaz-bala-betaph
765: ibhs-oxadiaz-bala-beta4bph765: ibhs-oxadiaz-bala-beta4bph
766: bim-me25thiaz-leu-zdap766: bim-me25thiaz-leu-zdap
767: 2py-25methiaz-ala-psdap 2o 768: bhs-42oxaz-ala-betadcph767: 2py-25methiaz-ala-psdap 2o 768: bhs-42oxaz-ala-betadcph
769: bhs-25methiaz-gly-betainyl769: bhs-25methiaz-gly-betainyl
770: bim-triaz-gly-betadcph770: bim-triaz-gly-betadcph
771 : tolhs-24thiaz-bala-betabthioph771: tolhs-24thiaz-bala-betabthioph
772: bhs-nme35pyr-bala-busu2be772: bhs-nme35pyr-bala-busu2be
773: bhs-25oxaz-nmgly-betainyl773: bhs-25oxaz-nmgly-betainyl
25 774: phhs-me25thiaz-gly-betapy25 774: phhs-me25thiaz-gly-betapy
775: bhs-ithiadiaz-gly-beta4bph775: bhs-ithiadiaz-gly-beta4bph
776: phhs-me25thiaz-bala-betadcph776: phhs-me25thiaz-bala-betadcph
777: bhs-25thiaz-gly-zdap777: bhs-25thiaz-gly-zdap
778: phhs-24thiaz-bala-betah35dc 30 779: tolhs-nme35pyr-bala-betahmofu778: phhs-24thiaz-bala-betah35dc 30 779: tolhs-nme35pyr-bala-betahmofu
780: bhs-24thiaz-bala-betabdimo780: bras-24thiaz-bala-betabdimo
781: bim-ithiadiaz-gly-zdap781: bim-ithiadiaz-gly-zdap
782: ibhs-24thioph-gly-betadbph782: ibhs-24thioph-gly-betadbph
783: bhs-me25oxaz-gly-betapy 35 784: bhs-24thiaz-ala-beta23meoph783: bhs-me25oxaz-gly-betapy 35 784: bhs-24thiaz-ala-beta23meoph
785: ibhs-nme35pyr-bala-betapytb785: ibhs-nme35pyr-bala-betapytb
786: bhs-25oxaz-gly-betaamibe786: bhs-25oxaz-gly-betaamibe
787: bhs-ithiadiaz-gly-betaoxope787: bhs-ithiadiaz-gly-betaoxope
788 : gua-25thioph-gly-betacthioph788: gua-25thioph-gly-betacthioph
789: bhs-oxadiaz-gly-betapyr789: bhs-oxadiaz-gly-betapyr
40 790 : phhs-me25oxaz-ala-beta34meoph40 790: phhs-me25oxaz-ala-beta34meoph
791: bhs-ithiadiaz-gly-betadmph791: bhs-ithiadiaz-gly-betadmph
792: bim-25methiaz-bala-betaimid792: bim-25methiaz-bala-betaimide
793: ibhs-oxadiaz-bala-betameph793: ibhs-oxadiaz-bala-betameph
794: ibhs-oxadiaz-bala-betahph 45 795: phhs-24thioph-gly-betathio3794: ibhs-oxadiaz-bala-betahph 45 795: phhs-24thioph-gly-betathio3
796: tolhs-nme35pyr-bala-betapyr796: tolhs-nme35pyr-bala-betapyr
797: ibhs-ithiadiaz-gly-beta ethi 798: phhs-24thiaz-bala-beta3quin797: ibhs-ithiadiaz-gly-beta ethi 798: phhs-24thiaz-bala-beta3quin
799: ibhs-nme35pyr-gly-betaipro799: ibhs-nme35pyr-gly-betaipro
800: ibhs-oxadiaz-gly-aspbzla800: ibhs-oxadiaz-gly-aspbzla
801: bhs-25thiaz-bala-betamesu 5 802: bim-35fur-bala-zdap801: bhs-25thiaz-bala-betamesu 5 802: bim-35fur-bala-zdap
803: tolhs-nme35pyr-gly-betabph803: tolhs-nme35pyr-gly-betabph
804 : phhs-ithiadiaz-bala-betaphethioa804: phhs-ithiadiaz-bala-betaphethioa
805: ibhs-nme35pyr-gly-ibsdap805: ibhs-nme35pyr-gly-ibsdap
806: bim-24thiaz-leu-betapy806: bim-24thiaz-leu-betapy
807: thpy -25methiaz-gly-betadcph807: thpy -25methiaz-gly-betadcph
10 808: phhs-24thioph-gly-betabenfu10 808: phhs-24thioph-gly-betabenfu
809: ibhs-25methiaz-gly-betapych809: ibhs-25methiaz-gly-betapych
810: ibhs-oxadiaz-gly-betaph810: ibhs-oxadiaz-gly-betaph
811: bhs-25thiaz-gly-betaftrif811: bhs-25thiaz-gly-betaftrif
812: phhs-nme35pyr-bala-betapym 15 813: tolhs-25thiaz-gly-betameph812: phhs-nme35pyr-bala-betapym 15 813: tolhs-25thiaz-gly-betameph
814: 2py-25methiaz-bala-betaheph814: 2py-25methiaz-bala-betaheph
815: 2py-25methiaz-gly-aspaba815: 2py-25methiaz-gly-aspaba
816: phhs-24thiaz-bala-betapych816: phhs-24thiaz-bala-betapych
817: bhs-35fur-bala-betadcph 20 818: phhs-ithiadiaz-gly-suabu817: bhs-35fur-bala-betadcph 20 818: phhs-ithiadiaz-gly-suabu
819: 2py-42pym-gly-zdap819: 2py-42pym-gly-zdap
820: ibhs-ithiadiaz-gly-betaimid820: ibhs-ithiadiaz-gly-betaimide
821: tolhs-25oxaz-gly-betahdbph821: tolhs-25oxaz-gly-betahdbph
822: ibhs-25oxaz-bala-betahbcph822: ibhs-25oxaz-bala-betahbcph
823 : ibhs-ithiadiaz-bala-betaoxope823: ibhs-ithiadiaz-bala-betaoxope
25 824: tolhs-oxadiaz-gly-ibsdap25 824: tolhs-oxadiaz-gly-ibsdap
825: tolhs-nme35pyr-bala-betabenfu825: tolhs-nme35pyr-bala-betabenfu
826: bhs-24thioph-gly-betaphethioa826: bhs-24thioph-gly-betaphethioa
827 : bhs-me25thiaz-bala-betadcph 828: tolhs-me24oxaz-bala-betaph827: bhs-me25thiaz-bala-betadcph 828: tolhs-me24oxaz-bala-betaph
30 829: phhs-ithiadiaz-bala-betafbph30 829: phhs-ithiadiaz-bala-betafbph
830: ibhs-24thioph-gly-betabediox830: ibhs-24thioph-gly-betabediox
831: tolhs-me25thioph-bala-zdap831: tolhs-me25thioph-bala-zdap
832: tolhs-oxadiaz-bala-betapym832: tolhs-oxadiaz-bala-betapym
833: bhs-25oxaz-gly-zdaptb 35 834: ibhs-ithiadiaz-bala-betal3bendi833: bhs-25oxaz-gly-zdaptb 35 834: ibhs-ithiadiaz-bala-betal3bendi
835: bhs-nme35pyr-ba1a-betatbuph 836 : phhs-oxadiaz-gly-betaphethioa 837: dhim-thiadiaz-gly-betameph 838 : bhs-24thioph-nmgly-betacthioph 839 : phhs-25methiaz-bala-betaoxaz835: bhs-nme35pyr-ba1a-betatbuph 836: phhs-oxadiaz-gly-betaphethioa 837: dhim-thiadiaz-gly-betameph 838: bhs-24thioph-nmgly-betacthioph 839: phhs-25methiaz-bala-betaoxaz
40 840: ibhs-24thiaz-gly-betaimid40 840: ibhs-24thiaz-gly-betaimide
841: phhs-24thioph-bala-betabnaphth 842: bhs-24im-bala-betapy 843: tolhs-24thiaz-gly-betabph 844: 2py-25methiaz-gly-aspbzla 45 845: 2pmhs-25thiaz-phe-zdap 846: 2pιrths-24thiaz-gly-betahb 847: bhs-24thiaz-gly-betambiph 848: phhs-25oxaz-gly-psdapch 849: ibhs-24thiaz-gly-beta4bph 850: bim-ithiadiaz-bala-betadcph841: phhs-24thioph-bala-betabnaphth 842: bhs-24im-bala-betapy 843: tolhs-24thiaz-gly-betabph 844: 2py-25methiaz-gly-aspbzla 45 845: 2 pmhs-25thiaz-phe-zdap 846: 2pιrths- 24thiaz-gly-betahb 847: bhs-24thiaz-gly-betambiph 848: phhs-25oxaz-gly-psdapch 849: ibhs-24thiaz-gly-beta4bph 850: bim-ithiadiaz-bala-betadcph
851: tolhs-25thiaz-gly-betahdcph 5 852: bhs-ithiadiaz-bala-betamethioph851: tolhs-25thiaz-gly-betahdcph 5 852: bhs-ithiadiaz-bala-betamethioph
853: ibhs-25oxaz-gly-ibsdap853: ibhs-25oxaz-gly-ibsdap
854: ibhs-25oxaz-gly-betabthioph854: ibhs-25oxaz-gly-betabthioph
855: bhs-25methiaz-leu-psdap855: bhs-25methiaz-leu-psdap
856: bhs-25thiaz-bala-betabph856: bras-25thiaz-bala-betabph
857 : tolhs-nme35pyr-bala-betaanaphth857: tolhs-nme35pyr-bala-betaanaphth
10 858: bim-me24thioph-leu-betaph10 858: bim-me24thioph-leu-betaph
859: thpy-42pym-gly-betadcph859: thpy-42pym-gly-betadcph
860: thpy -25oxaz-bala-zdap860: thpy -25oxaz-bala-zdap
861 : ibhs-ithiadiaz-bala-betahmofu861: ibhs-ithiadiaz-bala-betahmofu
862 : ibhs-oxadiaz-gly-betabph 15 863: bhs-24thiaz-bala-betal3bendi862: ibhs-oxadiaz-gly-betabph 15 863: bhs-24thiaz-bala-betal3bendi
864: dhim-24oxaz-ala-betainyl864: dhim-24oxaz-ala-betainyl
865: tolhs-nme35pyr-gly-betaoxaz865: tolhs-nme35pyr-gly-betaoxaz
866: tolhs-oxadiaz-gly-betathio3866: tolhs-oxadiaz-gly-betathio3
867: bhs-25fur-gly-zdap 2o 868: bim-24im-ala-psdap867: bhs-25fur-gly-zdap 2o 868: bim-24im-ala-psdap
869: ibhs-nme35pyr-bala-betabmph869: ibhs-nme35pyr-bala-betabmph
870: bhs-ithiadiaz-ala-betathio3870: bhs-ithiadiaz-ala-betathio3
871: tolhs-25thiaz-gly-beta34meoph871: tolhs-25thiaz-gly-beta34meoph
872: tolhs-24thioph-gly-betahmofu872: tolhs-24thioph-gly-betahmofu
873: phhs-25oxaz-gly-zdap873: phhs-25oxaz-gly-zdap
25 874: 2pmhs-42nmeim-bala-betabph25 874: 2 pmhs-42nmeim-bala-betabph
875: tolhs-25oxaz-bala-busu2be875: tolhs-25oxaz-bala-busu2be
876 : phhs-ithiadiaz-gly-betathioph876: phhs-ithiadiaz-gly-betathioph
877: bhs-25fur-ala-psdap877: bhs-25fur-ala-psdap
878: tolhs-25methiaz-bala-betaphethio 30 879: phhs-oxadiaz-bala-betathiobe878: tolhs-25methiaz-bala-betaphethio 30 879: phhs-oxadiaz-bala-betathiobe
880: ibhs-24thioph-gly-betaibph880: ibhs-24thioph-gly-betaibph
881: tolhs-25thiaz-gly-betadito881: tolhs-25thiaz-gly-betadito
882: tolhs-25thiaz-gly-betahc882: tolhs-25thiaz-gly-betahc
883 : tolhs-24thiaz-bala-betabenfu 35 884: 2py-25thiaz-bala-aspibua883: tolhs-24thiaz-bala-betabenfu 35 884: 2py-25thiaz-bala-aspibua
885: impy-25thiaz-gly-betaipr885: impy-25thiaz-gly-betaipr
886: phhs-ithiadiaz-bala-beta35dbph886: phhs-ithiadiaz-bala-beta35dbph
887 : phhs-25thiaz-bala-suabu887: phhs-25thiaz-bala-suabu
888: phhs-24thiaz-bala-betapym888: phhs-24thiaz-bala-betapym
889: dhim-52thiaz-gly-zdap889: dhim-52thiaz-gly-zdap
40 890 : ibhs-24thioph-bala-betathiome40 890: ibhs-24thioph-bala-betathiome
891: bim-42nmeim-ba1a-betadcph891: bim-42nmeim-ba1a-betadcph
892 : tolhs-ithiadiaz-gly-betaoxaz892: tolhs-ithiadiaz-gly-betaoxaz
893: phhs-25thiaz-bala-betamethi893: phhs-25thiaz-bala-betamethi
894 : phhs-24thiaz-gly-betaphethioa 45 895: bhs-ithiadiaz-ala-betacthioph894: phhs-24thiaz-gly-betaphethioa 45 895: bhs-ithiadiaz-ala-betacthioph
896: phhs-nme35pyr-bala-betahbcph896: phhs-nme35pyr-bala-betahbcph
897: phhs-me24thiaz-bala-betadcph 898: hs-25oxaz-gly-betadcph897: phhs-me24thiaz-bala-betadcph 898: hs-25oxaz-gly-betadcph
899: ibhs-25oxaz-gly-beta3quin899: ibhs-25oxaz-gly-beta3quin
900: tolhs-24thioph-bala-betaibph900: tolhs-24thioph-bala-betaibph
901: tolhs-24thioph-bala-betahb 5 902: thazep-24thiaz-gly-betapy901: tolhs-24thioph-bala-betahb 5 902: thazep-24thiaz-gly-betapy
903: ibhs-nme35pyr-bala-beta3quin903: ibhs-nme35pyr-bala-beta3quin
904: tolhs-25oxaz-bala-betaamibe904: tolhs-25oxaz-bala-betaamibe
905: bhs-oxadiaz-ala-zdap905: bras-oxadiaz-ala-zdap
906: tolhs-24thioph-bala-beta4bph906: tolhs-24thioph-bala-beta4bph
907 : phhs-ithiadiaz-bala-betapbiph907: phhs-ithiadiaz-bala-betapbiph
10 908: gua-42pym-gly-betafph10 908: gua-42pym-gly-betafph
909: phhs-nme35pyr-gly-betatbuph909: phhs-nme35pyr-gly-betatbuph
910 : tolhs-nme35pyr-bala-beta34dcph910: tolhs-nme35pyr-bala-beta34dcph
911: phhs-24thiaz-bala-aspibua911: phhs-24thiaz-bala-aspibua
912 : 2py-25thioph-ala-betameph 15 913: bim-me25thioph-leu-beta34meoph912: 2py-25thioph-ala-betameph 15 913: bim-me25thioph-leu-beta34meoph
914: 2py-me25oxaz-leu-betapy914: 2py-me25oxaz-leu-betapy
915: 2py-24thioph-gly-aspibua915: 2py-24thioph-gly-aspibua
916: ibhs-25oxaz-gly-betadcphtb916: ibhs-25oxaz-gly-betadcphtb
917: gua-42pym-gly-betadcph 20 918: bhs-24thiaz-bala-betadcphee917: gua-42pym-gly-betadcph 20 918: bhs-24thiaz-bala-betadcphee
919: tolhs-25oxaz-bala-psdapee919: tolhs-25oxaz-bala-psdapee
920: tolhs-oxadiaz-bala-betaftrif920: tolhs-oxadiaz-bala-betaftrif
921 : ibhs-oxadiaz-gly-betatbuph921: ibhs-oxadiaz-gly-betatbuph
922: bhs-me24oxaz-ala-betadcph922: bhs-me24oxaz-ala-betadcph
923 : tolhs-ithiadiaz-bala-betafu3923: tolhs-ithiadiaz-bala-betafu3
25 924: ibhs-24thioph-bala-zdaptb25 924: ibhs-24thioph-bala-zdaptb
925: phhs-25thiaz-bala-betadbph925: phhs-25thiaz-bala-betadbph
926: 2py-42oxaz-leu-zdap926: 2py-42oxaz-leu-zdap
927: bhs-oxadiaz-bala-betahmofu927: bras-oxadiaz-bala-betahmofu
928: ibhs-25methiaz-gly-betathiome 30 929: phhs-nme35pyr-bala-betadito928: ibhs-25methiaz-gly-betathiome 30 929: phhs-nme35pyr-bala-betadito
930 : phhs-24thioph-gly-beta34meoph 931 : tolhs-nme35pyr-bala-betainyl 932 : phhs-me24thioph-gly-beta34meoph 933: bim-me25thiaz-gly-betadcph930: phhs-24thioph-gly-beta34meoph 931: tolhs-nme35pyr-bala-betainyl 932: phhs-me24thioph-gly-beta34meoph 933: bim-me25thiaz-gly-betadcph
35 934: bhs-24thiaz-ala-csdap35 934: bhs-24thiaz-ala-csdap
935: phhs-24thioph-gly-aspbzla935: phhs-24thioph-gly-aspbzla
936: bim-25thiaz-gly-betatrif936: bim-25thiaz-gly-betatrif
937: impy-24thioph-gly-betacbph937: impy-24thioph-gly-betacbph
938: dhpyrr-25methiaz-gly-betapy938: dhpyrr-25methiaz-gly-betapy
939 : bhs-24thiaz-bala-betadmoph939: bras-24thiaz-bala-betadmoph
40 940: bhs-42pym-gly-psdap40 940: bhs-42pym-gly-psdap
941: phhs-ithiadiaz-bala-betapyee941: phhs-ithiadiaz-bala-betapyee
942 : phhs-24thioph-bala-betathiobe942: phhs-24thioph-bala-betathiobe
943: bim-35thioph-leu-psdap943: bim-35thioph-leu-psdap
944: phhs-me24oxaz-leu-betapy 45 945: phhs-24thioph-bala-betacph944: phhs-me24oxaz-leu-betapy 45 945: phhs-24thioph-bala-betacph
946: ibhs-25methiaz-bala-betatos946: ibhs-25methiaz-bala-betatos
947: tolhs-25oxaz-bala-betaoxope 948: gua-24oxaz-gly-betamethioph947: tolhs-25oxaz-bala-betaoxope 948: gua-24oxaz-gly-betamethioph
949: tolhs-25methiaz-gly-suabu949: tolhs-25methiaz-gly-suabu
950: phhs-24thiaz-bala-betamethi950: phhs-24thiaz-bala-betamethi
951: phhs-ithiadiaz-gly-betadhbfu 5 952: gua-24thiaz-gly-betadbph951: phhs-ithiadiaz-gly-betadhbfu 5 952: gua-24thiaz-gly-betadbph
953 : bhs-25methiaz-nmgly-betabnaphth953: bhs-25methiaz-nmgly-beta-naphth
954: bhs-24thioph-leu-betapy954: bhs-24thioph-leu-betapy
955: phhs-25thiaz-gly-betacthioph955: phhs-25thiaz-gly-betacthioph
956: bim-25oxaz-bala-aspaba956: bim-25oxaz-bala-aspaba
957: phhs-ithiadiaz-bala-psdapee957: phhs-ithiadiaz-bala-psdapee
10 958: tolhs-oxadiaz-bala-busu2be10 958: tolhs-oxadiaz-bala-busu2be
959: phhs-me24thiaz-bala-betapy959: phhs-me24thiaz-bala-betapy
960 : phhs-me24thioph-leu-beta34meoph960: phhs-me24thioph-leu-beta34meoph
961: phhs-24thioph-gly-betapbiph961: phhs-24thioph-gly-betapbiph
962 : bhs-ithiadiaz-bala-beta34dcph 15 963: bim-me24thiaz-ala-betaph962: bhs-ithiadiaz-bala-beta34dcph 15 963: bim-me24thiaz-ala-betaph
964 : bhs-nme35pyr-bala-psdapch964: bhs-nme35pyr-bala-psdapch
965: phhs-24thiaz-bala-betabmph965: phhs-24thiaz-bala-betabmph
966: phhs-24thiaz-gly-betadmph966: phhs-24thiaz-gly-betadmph
967: bim-triaz-ala-zdap 20 968: thpym-25oxaz-gly-betameph967: bim-triaz-ala-zdap 20 968: thpym-25oxaz-gly-betameph
969: bim-24thiaz-gly-betaibph969: bim-24thiaz-gly-betaibph
970: tolhs-24thiaz-gly-betaheph970: tolhs-24thiaz-gly-betaheph
971: tolhs-ithiadiaz-gly-zdaptb971: tolhs-ithiadiaz-gly-zdaptb
972: bim-26pyrazi-gly-zdap972: bim-26pyrazi-gly-zdap
973: ibhs-24thioph-gly-betaol973: ibhs-24thioph-gly-betaol
25 974: bim-me25thiaz-gly-betaph25 974: bim-me25thiaz-gly-betaph
975: ibhs-25methiaz-bala-betadcphch975: ibhs-25methiaz-bala-betadcphch
976: phhs-24thioph-gly-psdapch976: phhs-24thioph-gly-psdapch
977: phhs-24thioph-gly-betahdbph977: phhs-24thioph-gly-betahdbph
978: phhs-me25oxaz-gly-betapy 30 979: dhim-24thiaz-gly-betadcph978: phhs-me25oxaz-gly-betapy 30 979: dhim-24thiaz-gly-betadcph
980: bim-me24thiaz-ala-betadcph980: bim-me24thiaz-ala-betadcph
981: bhs-nme35pyr-gly-betaomebendi981: bhs-nme35pyr-gly-betaomebendi
982: phhs-oxadiaz-bala-psdapee982: phhs-oxadiaz-bala-psdapee
983: bhs-24thioph-bala-betahc 35 984: ibhs-24thiaz-bala-betathiobe983: bhs-24thioph-bala-betahc 35 984: ibhs-24thiaz-bala-betathiobe
985 : bhs-25methiaz-gly-betal3bendi985: bhs-25methiaz-gly-betal3bendi
986: phhs-oxadiaz-bala-busu2be986: phhs-oxadiaz-bala-busu2be
987: phhs-ithiadiaz-gly-betafu3987: phhs-ithiadiaz-gly-betafu3
988: phhs-24thioph-gly-betaimid988: phhs-24thioph-gly-betaimide
989: tolhs-25thiaz-bala-beta35dbph989: tolhs-25thiaz-bala-beta35dbph
40 990: bhs-oxadiaz-gly-betacthioph40 990: bhs-oxadiaz-gly-betacthioph
991: bhs-ithiadiaz-gly-betapych991: bhs-ithiadiaz-gly-betapych
992: bim-24oxaz-gly-psdap992: bim-24oxaz-gly-psdap
993: tolhs-me24thiaz-bala-betapy993: tolhs-me24thiaz-bala-betapy
994: bhs-25oxaz-gly-betathio3 45 995: bim-oxadiaz-bala-betadcph994: bhs-25oxaz-gly-betathio3 45 995: bim-oxadiaz-bala-betadcph
996 : phhs-nme35pyr-gly-betafu3996: phhs-nme35pyr-gly-betafu3
997: dhim-25thiaz-ala-betapy 998: agua-25methiaz-gly-psdap997: dhim-25thiaz-ala-betapy 998: agua-25methiaz-gly-psdap
999: bim-nme35pyr-leu-zdap999: bim-nme35pyr-leu-zdap
1000: tolhs-24thiaz-bala-betahmo1000: tolhs-24thiaz-bala-betahmo
1001: bim-35fur-bala-psdap 5 1002: bhs-24thiaz-gly-betadmoph1001: bim-35fur-bala-psdap 5 1002: bhs-24thiaz-gly-betadmoph
1003: dhim-25methiaz-gly-betapy1003: dhim-25methiaz-gly-betapy
1004 : phhs-25methiaz-gly-betapytb1004: phhs-25methiaz-gly-betapytb
1005: 2py-me25oxaz-leu-beta34meoph1005: 2py-me25oxaz-leu-beta34meoph
1006: gua-24thiaz-gly-betapym1006: gua-24thiaz-gly-betapym
1007: bim-35fur-leu-zdap1007: bim-35fur-leu-zdap
10 1008: bhs-25thioph-leu-betadcph10 1008: bhs-25thioph-leu-betadcph
1009: ibhs-25thiaz-bala-betameph1009: ibhs-25thiaz-bala-betameph
1010: bhs-24thioph-gly-psdap1010: bhs-24thioph-gly-psdap
1011: 2py-35fur-gly-psdap1011: 2py-35fur-gly-psdap
1012 : ibhs-oxadiaz-bala-busu2be 15 1013 : ibhs-oxadiaz-bala-zdap1012: ibhs-oxadiaz-bala-busu2be 15 1013: ibhs-oxadiaz-bala-zdap
1014: bhs-25methiaz-gly-betahb1014: bhs-25methiaz-gly-betahb
1015: tolhs-25oxaz-bala-beta4bph1015: tolhs-25oxaz-bala-beta4bph
1016 : phhs-me24oxaz-bala-beta34meoph1016: phhs-me24oxaz-bala-beta34meoph
1017: tolhs-25oxaz-gly-beta4bph 2o 1018: bim-35thioph-gly-betadcph1017: tolhs-25oxaz-gly-beta4bph 2o 1018: bim-35thioph-gly-betadcph
1019: bhs-25oxaz-bala-beta3quin1019: bras-25oxaz-bala-beta3quin
1020: impy-25thiaz-gly-betabediox1020: impy-25thiaz-gly-betabediox
1021: bhs-nme35pyr-bala-betabmph1021: bhs-nme35pyr-bala-betabmph
1022 : phhs-me24oxaz-gly-beta34meoph1022: phhs-me24oxaz-gly-beta34meoph
1023 : tolhs-24thioph-bala-betaipr1023: tolhs-24thioph-bala-betaipr
25 1024 : 2py-me25thioph-leu-betadcph25 1024: 2py-me25thioph-leu-betadcph
1025: ibhs-24thiaz-bala-betaol1025: ibhs-24thiaz-bala-betaol
1026: ibhs-24thioph-gly-betatos1026: ibhs-24thioph-gly-betatos
1027: phhs-25thiaz-gly-betahni1027: phhs-25thiaz-gly-betahni
1028: tolhs-24thioph-bala-betamethi 30 1029: tolhs-24thiaz-gly-betafu21028: tolhs-24thioph-bala-betamethi 30 1029: tolhs-24thiaz-gly-betafu2
1030 : ibhs-ithiadiaz-gly-betathioph1030: ibhs-ithiadiaz-gly-betathioph
1031: 2py-42nmeim-ala-betadcph1031: 2py-42nmeim-ala-betadcph
1032: phhs-24thioph-bala-aspibua1032: phhs-24thioph-bala-aspibua
1033: 2py-25thiaz-gly-zdap 35 1034: bhs-25thiaz-gly-psdapch1033: 2py-25thiaz-gly-zdap 35 1034: bhs-25thiaz-gly-psdapch
1035 : gua-42pym-gly-betadito1035: gua-42pym-gly-betadito
1036: ibhs-25oxaz-gly-betahdcph1036: ibhs-25oxaz-gly-betahdcph
1037 : tolhs-oxadiaz-bala-betathiome1037: tolhs-oxadiaz-bala-betathiome
1038: phhs-25thiaz-bala-betaftrif1038: phhs-25thiaz-bala-betaftrif
1039 : phhs-ithiadiaz-bala-betabdimo1039: phhs-ithiadiaz-bala-betabdimo
40 1040 : bhs-nme35pyr-ala-betal3bendi40 1040: bhs-nme35pyr-ala-betal3bendi
1041 : ibhs-25methiaz-gly-betadtrif1041: ibhs-25methiaz-gly-betadtrif
1042: dhim-25thiaz-gly-betainyl1042: dhim-25thiaz-gly-betainyl
1043: bim-24thiaz-bala-betapy1043: bim-24thiaz-bala-betapy
1044 : bhs-25thiaz-nmgly-betathioph 45 1045: bhs-25thiaz-gly-betatbuph1044: bhs-25thiaz-nmgly-betathioph 45 1045: bhs-25thiaz-gly-betatbuph
1046 : tolhs-ithiadiaz-gly-aspibua1046: tolhs-ithiadiaz-gly-aspibua
1047: phhs-ithiadiaz-bala-ibsdap 1048: bhs-24thiaz-bala-zdaptb1047: phhs-ithiadiaz-bala-ibsdap 1048: bras-24thiaz-bala-zdaptb
1049: ibhs-25methiaz-gly-busu2be1049: ibhs-25methiaz-gly-busu2be
1050: tolhs-oxadiaz-bala-betahmph1050: tolhs-oxadiaz-bala-betahmph
1051: phhs-ithiadiaz-gly-csdap 5 1052: impy-24thioph-bala-psdap1051: phhs-ithiadiaz-gly-csdap 5 1052: impy-24thioph-bala-psdap
1053: bim-me25thiaz-leu-psdap1053: bim-me25thiaz-leu-psdap
1054: phhs-ithiadiaz-gly-ibsdap1054: phhs-ithiadiaz-gly-ibsdap
1055: bhs-25methiaz-gly-betah35dc1055: bhs-25methiaz-gly-betah35dc
1056: bhs-25thiaz-met-betameph1056: bhs-25thiaz-met-betameph
1057: tolhs-25methiaz-bala-betainyl1057: tolhs-25methiaz-bala-betainyl
10 1058: phhs-25thiaz-gly-beta23meoph10 1058: phhs-25thiaz-gly-beta23meoph
1059: phhs-24thioph-gly-betafu21059: phhs-24thioph-gly-betafu2
1060: phhs-me24oxaz-gly-betadcph1060: phhs-me24oxaz-gly-betadcph
1061: tolhs-25thiaz-bala-betah35dc1061: tolhs-25thiaz-bala-betah35dc
1062: bhs-24thioph-bala-psdapch 15 1063: bhs-me24thioph-gly-beta34meoph1062: bhs-24thioph-bala-psdapch 15 1063: bhs-me24thioph-gly-beta34meoph
1064: tolhs-me24thiaz-ala-betaph1064: tolhs-me24thiaz-ala-betaph
1065: phhs-25methiaz-bala-betaibph1065: phhs-25methiaz-bala-betaibph
1066 : ibhs-ithiadiaz-gly-betadcph1066: ibhs-ithiadiaz-gly-betadcph
1067: phhs-24thiaz-gly-aspbzla 20 1068: tolhs-25methiaz-bala-betabdimo1067: phhs-24thiaz-gly-aspbzla 20 1068: tolhs-25methiaz-bala-betabdimo
1069: bhs-24thioph-ala-betadmph1069: bhs-24thioph-ala-betadmph
1070: gua-42pym-gly-betahcbph1070: gua-42pym-gly-betahcbph
1071: ibhs-25oxaz-bala-betamesu1071: ibhs-25oxaz-bala-betamesu
1072 : ibhs-25thiaz-bala-betahcbph1072: ibhs-25thiaz-bala-betahcbph
1073: bhs-24thiaz-gly-betabediox1073: bhs-24thiaz-gly-betabediox
25 1074: bhs-24thiaz-ala-betamesu25 1074: bhs-24thiaz-ala-betamesu
1075: gua-42pym-gly-betaet1075: gua-42pym-gly-betet
1076 : bhs-oxadiaz-bala-betathiome1076: bras-oxadiaz-bala-betathiome
1077 : ibhs-25thiaz-gly-betahb1077: ibhs-25thiaz-gly-betahb
1078: tolhs-ithiadiaz-bala-betadcphtb 30 1079: bhs-24thiaz-bala-betaoxaz1078: tolhs-ithiadiaz-bala-betadcphtb 30 1079: bhs-24thiaz-bala-betaoxaz
1080: bhs-24thioph-gly-zdap1080: bhs-24thioph-gly-zdap
1081: bim-nme35pyr-bala-betapy1081: bim-nme35pyr-bala-betapy
1082 : ibhs-ithiadiaz-gly-beta23meoph1082: ibhs-ithiadiaz-gly-beta23meoph
1083 : bhs-25thiaz-ala-beta34meoph 35 1084: tolhs-me25thioph-bala-betadcph1083: bhs-25thiaz-ala-beta34meoph 35 1084: tolhs-me25thioph-bala-betadcph
1085: bhs-ithiadiaz-bala-betaol1085: bhs-ithiadiaz-bala-betaol
1086: phhs-24thiaz-gly-betacbph1086: phhs-24thiaz-gly-betacbph
1087 : phhs-25methiaz-bala-betabenfu1087: phhs-25methiaz-bala-betabenfu
1088: bim-nme35pyr-leu-betapy1088: bim-nme35pyr-leu-betapy
1089: 2py-35fur-leu-zdap1089: 2py-35fur-leu-zdap
40 1090: ibhs-24thioph-gly-betabpy40 1090: ibhs-24thioph-gly-betabpy
1091: tolhs-25thiaz-bala-betathiome1091: tolhs-25thiaz-bala-betathiome
1092: phhs-24thioph-bala-busu2be1092: phhs-24thioph-bala-busu2be
1093 : tolhs-oxadiaz-gly-betaphethio1093: tolhs-oxadiaz-gly-betaphethio
1094: dhim-26py-ala-betathioph 45 1095: phhs-nme35pyr-gly-beta34dcph1094: dhim-26py-ala-betathioph 45 1095: phhs-nme35pyr-gly-beta34dcph
1096 : ibhs-25oxaz-bala-beta23meoph1096: ibhs-25oxaz-bala-beta23meoph
1097: bhs-25thiaz-ala-zdap 1098: dhthi-24thiaz-bala-betadcph1097: bhs-25thiaz-ala-zdap 1098: dhthi-24thiaz-bala-betadcph
1099 : bhs-nme35pyr-bala-betaoxaz1099: bhs-nme35pyr-bala-betaoxaz
1100 : ibhs-25methiaz-bala-betapytb1100: ibhs-25methiaz-bala-betapytb
1101: ibhs-nme35pyr-gly-betapytb 5 1102: tolhs-24thiaz-bala-betamesu1101: ibhs-nme35pyr-gly-betapytb 5 1102: tolhs-24thiaz-bala-betamesu
1103: bhs-24thioph-gly-betafu31103: bhs-24thioph-gly-betafu3
1104 : tolhs-oxadiaz-gly-betabenfu1104: tolhs-oxadiaz-gly-betabenfu
1105: tolhs-nme35pyr-gly-betafbph1105: tolhs-nme35pyr-gly-betafbph
1106: bim-ithiadiaz-bala-zdap1106: bim-ithiadiaz-bala-zdap
1107: gua-25thioph-gly-suabu1107: gua-25thioph-gly-suabu
1010
1108: bhs-oxadiaz-gly-betathiobe1108: bhs-oxadiaz-gly-betathiobe
1109: phhs-25oxaz-gly-betafluo1109: phhs-25oxaz-gly-betafluo
1110: 2py-me25oxaz-leu-psdap1110: 2py-me25oxaz-leu-psdap
1111: ibhs-25oxaz-bala-betahni1111: ibhs-25oxaz-bala-betahni
1112: ibhs-oxadiaz-gly-betaol 15 1113: tolhs-25thiaz-gly-betaftrif1112: ibhs-oxadiaz-gly-betaol 15 1113: tolhs-25thiaz-gly-betaftrif
1114 : tolhs-25oxaz-bala-betabdimo1114: tolhs-25oxaz-bala-betabdimo
1115: tolhs-25oxaz-gly-asppha1115: tolhs-25oxaz-gly-asppha
1116: bhs-me24thiaz-ala-betaph1116: bhs-me24thiaz-ala-betaph
1117: tolhs-24thiaz-gly-betafbph 20 1118: 2py-oxadiaz-gly-psdap1117: tolhs-24thiaz-gly-betafbph 20 1118: 2py-oxadiaz-gly-psdap
1119: bhs-25thiaz-bala-betahb1119: bras-25thiaz-bala-betahb
1120: bim-35fur-leu-psdap1120: bim-35fur-leu-psdap
1121: bhs-ithiadiaz-nmgly-ibsdap1121: bhs-ithiadiaz-nmgly-ibsdap
1122: bhs-24oxaz-ala-betameph1122: bras-24oxaz-ala-betameph
1123: bhs-nme35pyr-bala-betapyr1123: bhs-nme35pyr-bala-betapyr
25 1124: bhs-nme35pyr-ala-betapy25 1124: bhs-nme35pyr-ala-betapy
1125: tolhs-24thioph-gly-betaftrif1125: tolhs-24thioph-gly-betaftrif
1126 : phhs-25oxaz-gly-betaphethioa1126: phhs-25oxaz-gly-betaphethioa
1127: tolhs-nme35pyr-gly-csdap1127: tolhs-nme35pyr-gly-csdap
1128: 2py-25fur-bala-zdap 30 1129: 2py-24oxaz-leu-psdap1128: 2py-25fur-bala-zdap 30 1129: 2py-24oxaz-leu-psdap
1130: tolhs-24thiaz-bala-zdapch1130: tolhs-24thiaz-bala-zdapch
1131: phhs-oxadiaz-gly-betaoxope1131: phhs-oxadiaz-gly-betaoxope
1132: ibhs-24thiaz-bala-betapym1132: ibhs-24thiaz-bala-betapym
1133: thpym-24thiaz-gly-beta35dbph 35 1134: phhs-ithiadiaz-bala-betadmph1133: thpym-24thiaz-gly-beta35dbph 35 1134: phhs-ithiadiaz-bala-betadmph
1135: phhs-me25thiaz-leu-betaph1135: phhs-me25thiaz-leu-betaph
1136: phhs-nme35pyr-bala-betadcphch1136: phhs-nme35pyr-bala-betadcphch
1137: 2py-me24thiaz-bala-betaph1137: 2py-me24thiaz-bala-betaph
1138: phhs-me24thioph-ala-betapy1138: phhs-me24thioph-ala-betapy
1139: ibhs-25thiaz-bala-csdap1139: ibhs-25thiaz-bala-csdap
4040
1140 : tolhs-oxadiaz-bala-betaamibe1140: tolhs-oxadiaz-bala-betaamibe
1141: ibhs-nme35pyr-gly-betabenfu1141: ibhs-nme35pyr-gly-betabenfu
1142: bhs-25thiaz-gly-betainyl1142: bhs-25thiaz-gly-betainyl
1143: bhs-25thiaz-gly-betahdcph1143: bhs-25thiaz-gly-betahdcph
1144: phhs-25thiaz-gly-betacph 45 1145: phhs-oxadiaz-gly-betafph1144: phhs-25thiaz-gly-betacph 45 1145: phhs-oxadiaz-gly-betafph
1146 : phhs-25oxaz-gly-betapym1146: phhs-25oxaz-gly-betapym
1147: tolhs-24thiaz-bala-betacph 1148: 2py-me24thioph-ala-betaph 1149: ibhs-24thiaz-bala-betaipro1147: tolhs-24thiaz-bala-betacph 1148: 2py-me24thioph-ala-betaph 1149: ibhs-24thiaz-bala-betaipro
1150: hyd-25thiaz-bala-betameph1150: hyd-25thiaz-bala-betameph
1151: bim-52thiaz-ala-betapy 5 1152: bim-me25thiaz-ala-beta34meoph1151: bim-52thiaz-ala-betapy 5 1152: bim-me25thiaz-ala-beta34meoph
1153: bhs-oxadiaz-bala-betabmph1153: bras-oxadiaz-bala-betabmph
1154: dhim-24thiaz-ala-psdap1154: dhim-24thiaz-ala-psdap
1155: ibhs-24thioph-bala-zdapee1155: ibhs-24thioph-bala-zdapee
1156: gua-25thiaz-gly-betahbcph1156: gua-25thiaz-gly-betahbcph
1157 : bhs-ithiadiaz-bala-betabthioph1157: bhs-ithiadiaz-bala-betabthioph
10 1158: tolhs-24thiaz-bala-betal3bendi10 1158: tolhs-24thiaz-bala-betal3bendi
1159: bim-me24oxaz-ala-beta34meoph1159: bim-me24oxaz-ala-beta34meoph
1160: bim-me25oxaz-gly-betapy1160: bim-me25oxaz-gly-betapy
1161: 2py-25methiaz-gly-aspibua1161: 2py-25methiaz-gly-aspibua
1162: bim-25thiaz-leu-betapy 15 1163: bhs-25thiaz-gly-betah35dc1162: bim-25thiaz-leu-betapy 15 1163: bhs-25thiaz-gly-betah35dc
1164 : tolhs-25thiaz-bala-betafbph1164: tolhs-25thiaz-bala-betafbph
1165: bhs-24thioph-bala-csdap1165: bhs-24thioph-bala-csdap
1166: dhim-25thiaz-gly-betahdcph1166: dhim-25thiaz-gly-betahdcph
1167 : bhs-25oxaz-nmgly-betacthioph 20 1168: tolhs-24thiaz-gly-betadcphtb1167: bhs-25oxaz-nmgly-betacthioph 20 1168: tolhs-24thiaz-gly-betadcphtb
1169: 2py-25methiaz-bala-psdap1169: 2py-25methiaz-bala-psdap
1170: bim-ithiadiaz-gly-betadcph1170: bim-ithiadiaz-gly-betadcph
1171: bim-25fur-gly-psdap1171: bim-25fur-gly-psdap
1172 : tolhs-ithiadiaz-gly-psdapch1172: tolhs-ithiadiaz-gly-psdapch
1173 : bhs-53pyrazo-gly-betadcph1173: bras-53pyrazo-gly-betadcph
25 1174: ibhs-oxadiaz-bala-betahb25 1174: ibhs-oxadiaz-bala-betahb
1175 : bhs-nme35pyr-gly-betaanaphth1175: bhs-nme35pyr-gly-betaanaphth
1176 : phhs-25thiaz-bala-psdapch1176: phhs-25thiaz-bala-psdapch
1177: tolhs-oxadiaz-bala-betahmo1177: tolhs-oxadiaz-bala-betahmo
1178: tolhs-25methiaz-bala-betathio3 30 H79: bim-25oxaz-ala-psdap1178: tolhs-25methiaz-bala-betathio3 30 H79: bim-25oxaz-ala-psdap
1180: bim-42nmeim-gly-betapy1180: bim-42nmeim-gly-betapy
1181 : ibhs-nme35pyr-bala-betah35dc1181: ibhs-nme35pyr-bala-betah35dc
1182 : tolhs-24thioph-gly-betabthioph1182: tolhs-24thioph-gly-betabthioph
1183 : tolhs-25methiaz-bala-betadito 35 1184: thpym-25thiaz-bala-psdap1183: tolhs-25methiaz-bala-betadito 35 1184: thpym-25thiaz-bala-psdap
1185: bhs-25oxaz-gly-zdap1185: bhs-25oxaz-gly-zdap
1186: bhs-25thiaz-phe-betameph1186: bhs-25thiaz-phe-betameph
1187 : bhs-25methiaz-gly-betathiobe1187: bhs-25methiaz-gly-betathiobe
1188: bhs-nme35pyr-bala-betameph1188: bhs-nme35pyr-bala-betameph
1189 : phhs-ithiadiaz-gly-betaoxope1189: phhs-ithiadiaz-gly-betaoxope
40 1190: tolhs-24thiaz-gly-betabpy40 1190: tolhs-24thiaz-gly-betabpy
1191: phhs-ithiadiaz-bala-psdap1191: phhs-ithiadiaz-bala-psdap
1192: bgua-42nmeim-gly-betadcph1192: bgua-42nmeim-gly-betadcph
1193: dhim-24oxaz-gly-betainyl1193: dhim-24oxaz-gly-betainyl
1194: impy-25oxaz-gly-betampy 45 1195: bhs-25methiaz-bala-betadmoph1194: impy-25oxaz-gly-betampy 45 1195: bhs-25methiaz-bala-betadmoph
1196: gua-24thiaz-gly-betadito1196: gua-24thiaz-gly-betadito
1197: ibhs-ithiadiaz-gly-busu2be 1198: bhs-oxadiaz-bala-betadito1197: ibhs-ithiadiaz-gly-busu2be 1198: bras-oxadiaz-bala-betadito
1199 : ibhs-24thiaz-bala-betaphethioa1199: ibhs-24thiaz-bala-betaphethioa
1200 : ibhs-ithiadiaz-bala-betatrif1200: ibhs-ithiadiaz-bala-betatrif
1201 : bhs-24thioph-ala-psdap 5 1202: ibhs-nme35pyr-bala-betahdbph1201: bhs-24thioph-ala-psdap 5 1202: ibhs-nme35pyr-bala-betahdbph
1203: bhs-24thioph-bala-psdap1203: bhs-24thioph-bala-psdap
1204 : 2py-25thiaz-gly-betatbuph1204: 2py-25thiaz-gly-betatbuph
1205: ibhs-24thioph-bala-beta3quin1205: ibhs-24thioph-bala-beta3quin
1206 : ibhs-ithiadiaz-bala-betaoxaz1206: ibhs-ithiadiaz-bala-betaoxaz
1207: bhs-me24oxaz-gly-zdap1207: bhs-me24oxaz-gly-zdap
10 1208: gua-24thiaz-gly-betah35dc10 1208: gua-24thiaz-gly-betah35dc
1209: ibhs-24thioph-gly-betatrif1209: ibhs-24thioph-gly-betatrif
1210: tolhs-25methiaz-gly-betambiph1210: tolhs-25methiaz-gly-betambiph
1211: thpym-26py-gly-betadcph1211: thpym-26py-gly-betadcph
1212: phhs-24thioph-bala-betahmph 15 1213: ibhs-25methiaz-bala-betadmph1212: phhs-24thioph-bala-betahmph 15 1213: ibhs-25methiaz-bala-betadmph
1214: tolhs-24thioph-gly-betafphe1214: tolhs-24thioph-gly-betafphe
1215: tolhs-25oxaz-bala-betabnaphth1215: tolhs-25oxaz-bala-betabnaphth
1216: bhs-24thioph-gly-betaoxope1216: bhs-24thioph-gly-betaoxope
1217: pahs-26py-gly-betapy 2o 1218: 2py-24im-gly-betadcph1217: pahs-26py-gly-betapy 2o 1218: 2py-24im-gly-betadcph
1219 : tolhs-nme35pyr-bala-betapytb1219: tolhs-nme35pyr-bala-betapytb
1220: phhs-nme35pyr-gly-betapyee1220: phhs-nme35pyr-gly-betapyee
1221: bhs-25thiaz-bala-betabmph1221: bras-25thiaz-bala-betabmph
1222 : gua-42pym-gly-betadmoph1222: gua-42pym-gly-betadmoph
1223 : ibhs-nme35pyr-bala-betathiome1223: ibhs-nme35pyr-bala-betathiome
25 1224 : ibhs-25methiaz-gly-betainyl25 1224: ibhs-25methiaz-gly-betainyl
1225: bhs-24thiaz-gly-betahcbph1225: bhs-24thiaz-gly-betahcbph
1226: ibhs-24thiaz-bala-psdap1226: ibhs-24thiaz-bala-psdap
1227: bhs-triaz-ala-zdap1227: bhs-triaz-ala-zdap
1228: dhim-24thiaz-ala-betameph 30 1229: ibhs-24thiaz-bala-betapych1228: dhim-24thiaz-ala-betameph 30 1229: ibhs-24thiaz-bala-betapych
1230 : ibhs-25methiaz-gly-betaoxope1230: ibhs-25methiaz-gly-betaoxope
1231 : tolhs-24thiaz-bala-betahbcph1231: tolhs-24thiaz-bala-betahbcph
1232 : tolhs-2 thioph-gly-betathio31232: tolhs-2 thioph-gly-betathio3
1233: tolhs-oxadiaz-gly-betapych 35 1234: tolhs-24thiaz-bala-betatbuph1233: tolhs-oxadiaz-gly-betapych 35 1234: tolhs-24thiaz-bala-betatbuph
1235: 2py-25oxaz-leu-betadcph1235: 2py-25oxaz-leu-betadcph
1236: ibhs-24thiaz-gly-betadito1236: ibhs-24thiaz-gly-betadito
1237 : tolhs-25thiaz-bala-betacthioph1237: tolhs-25thiaz-bala-betacthioph
1238: phhs-24thiaz-bala-betaimid1238: phhs-24thiaz-bala-betaimide
1239: ibhs-25methiaz-gly-betabnaphth1239: ibhs-25methiaz-gly-betabnaphth
40 1240: dhim-24oxaz-ala-betameph40 1240: dhim-24oxaz-ala-betameph
1241 : phhs-oxadiaz-gly-beta34meoph1241: phhs-oxadiaz-gly-beta34meoph
1242: 2py-oxadiaz-bala-asppha1242: 2py-oxadiaz-bala-asppha
1243: phhs-nme35pyr-gly-aspibua1243: phhs-nme35pyr-gly-aspibua
1244 : ibhs-nme35pyr-gly-betal3bendi 45 1245: bhs-oxadiaz-gly-betahb1244: ibhs-nme35pyr-gly-betal3bendi 45 1245: bhs-oxadiaz-gly-betahb
1246 : tolhs-24 hioph-gly-beta4bph1246: tolhs-24 hioph-gly-beta4bph
1247: ibhs-25oxaz-bala-betah35dc 1248: ibhs-25thiaz-gly-betaoxope1247: ibhs-25oxaz-bala-betah35dc 1248: ibhs-25thiaz-gly-betaoxope
1249 : thpym-25thioph-gly-betahcbph1249: thpym-25thioph-gly-betahcbph
1250: tolhs-25oxaz-bala-betahmofu1250: tolhs-25oxaz-bala-betahmofu
1251: bhs-42pym-ala-psdap 5 1252: bhs-24thiaz-nmgly-betaipro1251: bhs-42pym-ala-psdap 5 1252: bhs-24thiaz-nmgly-betaipro
1253: ibhs-nme35pyr-gly-betahmofu1253: ibhs-nme35pyr-gly-betahmofu
1254: phhs-ithiadiaz-gly-betapym1254: phhs-ithiadiaz-gly-betapym
1255 : ibhs-24thioph-bala-betahbcph1255: ibhs-24thioph-bala-betahbcph
1256 : tolhs-oxadiaz-bala-betadcphch1256: tolhs-oxadiaz-bala-betadcphch
1257: phhs-24thioph-bala-betabmph1257: phhs-24thioph-bala-betabmph
10 1258: phhs-25oxaz-bala-betaftrif10 1258: phhs-25oxaz-bala-betaftrif
1259: 2py-thiadiaz-ala-betadcph1259: 2py-thiadiaz-ala-betadcph
1260: phhs-me25thiaz-leu-psdap1260: phhs-me25thiaz-leu-psdap
1261: phhs-nme35pyr-gly-betapych1261: phhs-nme35pyr-gly-betapych
1262: bhs-oxadiaz-bala-betafu3 15 1263: 2pmhs-42nmeim-bala-betameph1262: bhs-oxadiaz-bala-betafu3 15 1263: 2 pmhs-42nmeim-bala-betameph
1264: ibhs-oxadiaz-bala-betabmph1264: ibhs-oxadiaz-bala-betabmph
1265: ibhs-25thiaz-bala-beta23meoph1265: ibhs-25thiaz-bala-beta23meoph
1266: gua-25thiaz-gly-betaph1266: gua-25thiaz-gly-betaph
1267: bhs-24thiaz-ser-betapy 20 1268: bhs-24thiaz-met-betadcph1267: bhs-24thiaz-ser-betapy 20 1268: bhs-24thiaz-met-betadcph
1269: bhs-ithiadiaz-gly-betacthioph1269: bhs-ithiadiaz-gly-betacthioph
1270: bhs-42pym-gly-betainy11270: bhs-42pym-gly-betainy1
1271: 2py-triaz-bala-zdap1271: 2py-triaz-bala-zdap
1272: 2py-me24oxaz-ala-zdap1272: 2py-me24oxaz-ala-zdap
1273: phhs-24thioph-bala-betahc1273: phhs-24thioph-bala-betahc
25 1274 : tolhs-24thioph-bala-psdapch25 1274: tolhs-24thioph-bala-psdapch
1275 : phhs-oxadiaz-gly-betainyl1275: phhs-oxadiaz-gly-betainyl
1276: bhs-25thiaz-nmgly-betamesu1276: bhs-25thiaz-nmgly-betamesu
1277 : ibhs-24thioph-bala-beta34dcph1277: ibhs-24thioph-bala-beta34dcph
1278: phhs-nme35pyr-bala-betameph 30 1279: phhs-24thioph-bala-betaamibe1278: phhs-nme35pyr-bala-betameph 30 1279: phhs-24thioph-bala-betaamibe
1280: 2py-oxadiaz-leu-psdap1280: 2py-oxadiaz-leu-psdap
1281: bim-25thiaz-ala-betadcph1281: bim-25thiaz-ala-betadcph
1282: bim-35thioph-gly-zdap1282: bim-35thioph-gly-zdap
1283: bim-35py-gly-zdap 35 1284: ibhs-25oxaz-bala-betapyee1283: bim-35py-gly-zdap 35 1284: ibhs-25oxaz-bala-betapyee
1285: tolhs-me24thiaz-bala-zdap1285: tolhs-me24thiaz-bala-zdap
1286 : tolhs-25thiaz-bala-betadito1286: tolhs-25thiaz-bala-betadito
1287: phhs-oxadiaz-gly-betadtrif1287: phhs-oxadiaz-gly-betadtrif
1288 : bhs-24thioph-gly-betathiobe1288: bhs-24thioph-gly-betathiobe
1289 : bhs-25thiaz-gly-betaphethioa1289: bhs-25thiaz-gly-betaphethioa
40 1290: tolhs-25oxaz-gly-betahc40 1290: tolhs-25oxaz-gly-betahc
1291: bhs-25oxaz-gly-betaimid1291: bhs-25oxaz-gly-betaimide
1292: tolhs-oxadiaz-bala-betaipr1292: tolhs-oxadiaz-bala-betaipr
1293: phhs-24thiaz-gly-betapyr1293: phhs-24thiaz-gly-betapyr
1294 : bhs-me25thioph-gly-betadcph 45 1295: phhs-nme35pyr-bala-betadmoph1294: bhs-me25thioph-gly-betadcph 45 1295: phhs-nme35pyr-bala-betadmoph
1296: phhs-24thioph-bala-betabpy1296: phhs-24thioph-bala-betabpy
1297 : phhs-24thioph-bala-beta23meoph 1298: phhs-24thiaz-bala-zdapch1297: phhs-24thioph-bala-beta23meoph 1298: phhs-24thiaz-bala-zdapch
1299: bhs-42oxaz-bala-zdap1299: bras-42oxaz-bala-zdap
1300 : ibhs-ithiadiaz-bala-betadcphee 1301: phhs-nme35pyr-bala-betambiph1300: ibhs-ithiadiaz-bala-betadcphee 1301: phhs-nme35pyr-bala-betambiph
5 1302: bim-42nmeim-bala-betacbph5 1302: bim-42nmeim-bala-betacbph
1303 : tolhs-25thiaz-bala-beta34dcph1303: tolhs-25thiaz-bala-beta34dcph
1304 : hs-25methiaz-bala-betapy1304: hs-25methiaz-bala-betapy
1305 : dhim-42pym-gly-betapy1305: dhim-42pym-gly-betapy
1306: bhs-42oxaz-leu-betapy1306: bras-42oxaz-leu-betapy
1307: bhs-24thiaz-nmgly-betadmph1307: bhs-24thiaz-nmgly-betadmph
10 1308: dhim-25thiaz-ala-psdap10 1308: dhim-25thiaz-ala-psdap
1309: phhs-25oxaz-bala-betamethi1309: phhs-25oxaz-bala-betamethi
1310: phhs-me24thiaz-ala-betaph1310: phhs-me24thiaz-ala-betaph
1311: ibhs-24thioph-gly-betameph1311: ibhs-24thioph-gly-betameph
1312: gua-24oxaz-gly-betaheph 15 1313: bhs-ithiadiaz-gly-betal3bendi1312: gua-24oxaz-gly-betaheph 15 1313: bhs-ithiadiaz-gly-betal3bendi
1314 : bhs-ithiadiaz-bala-betahcbph1314: bhs-ithiadiaz-bala-betahcbph
1315: bhs-nme35pyr-gly-betaheph1315: bhs-nme35pyr-gly-betaheph
1316: bhs-25thiaz-leu-psdap1316: bhs-25thiaz-leu-psdap
1317 : tolhs-25oxaz-bala-betadmoph 20 1318: bim-25thiophme-gly-zdap1317: tolhs-25oxaz-bala-betadmoph 20 1318: bim-25thiophme-gly-zdap
1319: bhs-nme35pyr-nmgly-betabnaphth1319: bhs-nme35pyr-nmgly-betabnaphth
1320: 2py-24thioph-bala-betahni1320: 2py-24thioph-bala-betahni
1321: phhs-oxadiaz-bala-psdapch1321: phhs-oxadiaz-bala-psdapch
1322 : ibhs-25thiaz-bala-betabediox1322: ibhs-25thiaz-bala-betabediox
1323: tolhs-25oxaz-gly-betafphe1323: tolhs-25oxaz-gly-betafphe
25 1324: ibhs-25methiaz-bala-beta4bph25 1324: ibhs-25methiaz-bala-beta4bph
1325: tolhs-25thiaz-gly-betadbph1325: tolhs-25thiaz-gly-betadbph
1326: dhim-26py-gly-zdap1326: dhim-26py-gly-zdap
1327 : ibhs-24thioph-gly-betacthioph1327: ibhs-24thioph-gly-betacthioph
1328: 2py-ithiadiaz-gly-psdap 30 1329: tolhs-me25oxaz-ala-betaph1328: 2py-ithiadiaz-gly-psdap 30 1329: tolhs-me25oxaz-ala-betaph
1330 : ibhs-nme35pyr-gly-betarnethioph1330: ibhs-nme35pyr-gly-betarnethioph
1331: bhs-ithiadiaz-bala-betabpy1331: bhs-ithiadiaz-bala-betabpy
1332: bhs-oxadiaz-bala-betabph1332: bras-oxadiaz-bala-betabph
1333: ibhs-oxadiaz-gly-betampy 35 1334: dhthi-26py-gly-betapy1333: ibhs-oxadiaz-gly-betampy 35 1334: dhthi-26py-gly-betapy
1335: bhs-25thiaz-gly-betadmph1335: bhs-25thiaz-gly-betadmph
1336 : bim-25methiaz-gly-betaomebendi1336: bim-25methiaz-gly-betaomebendi
1337 : tolhs-25thiaz-bala-betadhbfu1337: tolhs-25thiaz-bala-betadhbfu
1338: bhs-oxadiaz-nmgly-beta34meoph1338: bhs-oxadiaz-nmgly-beta34meoph
1339: bim-nme35pyr-bala-asppha1339: bim-nme35pyr-bala-asppha
40 1340: 2py-42nmeim-gly-betafphe40 1340: 2py-42nmeim-gly-betafphe
1341: bhs-35thioph-gly-psdap1341: bhs-35thioph-gly-psdap
1342: 2py-42nmeim-bala-betaanaphth1342: 2py-42nmeim-bala-betaanaphth
1343: phhs-25thiaz-gly-psdapch1343: phhs-25thiaz-gly-psdapch
1344 : bhs-25methiaz-bala-betabdimo 45 1345: tolhs-me24oxaz-gly-betaph1344: bhs-25methiaz-bala-betabdimo 45 1345: tolhs-me24oxaz-gly-betaph
1346 : ibhs-24thioph-bala-betadito1346: ibhs-24thioph-bala-betadito
1347 : bhs-24thioph-nmgly-betabnaphth 13 8 : bhs-oxadiaz-bala-betadcphtb1347: bhs-24thioph-nmgly-betabnaphth 13 8: bras-oxadiaz-bala-betadcphtb
1349: bhs-26py-ala-psdap1349: bhs-26py-ala-psdap
1350: bhs-24thioph-nmgly-betamesu1350: bhs-24thioph-nmgly-betamesu
1351 : tolhs-oxadiaz-bala-betaimid 5 1352: bhs-ithiadiaz-nmgly-betadito1351: tolhs-oxadiaz-bala-betaimid 5 1352: bhs-ithiadiaz-nmgly-betadito
1353: phhs-25methiaz-bala-zdapee1353: phhs-25methiaz-bala-zdapee
1354 : bhs-ithiadiaz-bala-betaphethioa1354: bhs-ithiadiaz-bala-betaphethioa
1355: impy-24thioph-gly-betambiph1355: impy-24thioph-gly-betambiph
1356: bhs-ithiadiaz-gly-betafu21356: bhs-ithiadiaz-gly-betafu2
1357 : bhs-ithiadiaz-nmgly-betathioph1357: bhs-ithiadiaz-nmgly-betathioph
10 1358: phhs-25oxaz-bala-suabu10 1358: phhs-25oxaz-bala-suabu
1359: bhs-25methiaz-bala-betacbph1359: bras-25methiaz-bala-betacbph
1360 : phhs-me24oxaz-bala-betadcph1360: phhs-me24oxaz-bala-betadcph
1361: dhim-25thiaz-gly-betadtrif1361: dhim-25thiaz-gly-betadtrif
1362 : bhs-24thioph-bala-betathiome 15 1363: phhs-25oxaz-gly-beta34dcph1362: bhs-24thioph-bala-betathiome 15 1363: phhs-25oxaz-gly-beta34dcph
1364 : tolhs-me25oxaz-bala-betadcph1364: tolhs-me25oxaz-bala-betadcph
1365: ibhs-25thiaz-gly-betaamibe1365: ibhs-25thiaz-gly-betaamibe
1366 : bhs-nme35pyr-nmgly-beta23meoph1366: bhs-nme35pyr-nmgly-beta23meoph
1367: 2py-24thiaz-gly-aspaba 2o 1368: gua-24thioph-bala-betadcph1367: 2py-24thiaz-gly-aspaba 2o 1368: gua-24thioph-bala-betadcph
1369 : tolhs-24thioph-gly-betamethioph1369: tolhs-24thioph-gly-betamethioph
1370: gua-24thiaz-gly-betaph1370: gua-24thiaz-gly-betaph
1371: 2py-25methiaz-bala-aspibua1371: 2py-25methiaz-bala-aspibua
1372: ibhs-25oxaz-gly-zdaptb1372: ibhs-25oxaz-gly-zdaptb
1373 : phhs-me25thiaz-leu-betadcph1373: phhs-me25thiaz-leu-betadcph
25 1374: bhs-nme35pyr-bala-psdaptb25 1374: bhs-nme35pyr-bala-psdaptb
1375: bhs-25methiaz-gly-betahcbph1375: bhs-25methiaz-gly-betahcbph
1376: ibhs-25methiaz-gly-betah35dc1376: ibhs-25methiaz-gly-betah35dc
1377: bhs-24thiaz-bala-aspaba1377: bras-24thiaz-bala-aspaba
1378: tolhs-ithiadiaz-bala-betal3bendi 30 1379: bhs-ithiadiaz-bala-betaph1378: tolhs-ithiadiaz-bala-betal3bendi 30 1379: bhs-ithiadiaz-bala-betaph
1380 : tolhs-oxadiaz-gly-betaoxope1380: tolhs-oxadiaz-gly-betaoxope
1381 : 2py-thiadiaz-gly-betapy1381: 2py-thiadiaz-gly-betapy
1382 : phhs-24thiaz-bala-betaphethioa1382: phhs-24thiaz-bala-betaphethioa
1383: gua-24thiaz-gly-beta35dbph 35 1384: bim-26py-gly-betainyl1383: gua-24thiaz-gly-beta35dbph 35 1384: bim-26py-gly-betainyl
1385: pahs-25thiaz-bala-betameph1385: pahs-25thiaz-bala-betameph
1386 : bim-thiadiaz-ala-psdap1386: bim-thiadiaz-ala-psdap
1387 : bhs-me24thiaz-leu-beta34meoph1387: bhs-me24thiaz-leu-beta34meoph
1388: phhs-25oxaz-gly-betambiph1388: phhs-25oxaz-gly-betambiph
1389 : phhs-oxadiaz-gly-betaomebendi1389: phhs-oxadiaz-gly-betaomebendi
40 1390: phhs-25oxaz-bala-betarnethioph40 1390: phhs-25oxaz-bala-betarnethioph
1391: dhim-24thiaz-gly-betapy1391: dhim-24thiaz-gly-betapy
1392: bim-24thioph-nmala-betadcph1392: bim-24thioph-nmala-betadcph
1393 : bhs-nme35pyr-gly-betampy1393: bhs-nme35pyr-gly-betampy
1394 : 2py-me24oxaz-bala-betapy 45 1395: 2py-25thioph-gly-zdap1394: 2py-me24oxaz-bala-betapy 45 1395: 2py-25thioph-gly-zdap
1396 : ibhs-24thioph-bala-betah35dc1396: ibhs-24thioph-bala-betah35dc
1397: phhs-me25thioph-gly-betadcph 1398: bhs-24thioph-bala-betapym 1399: tolhs-24thioph-gly-aspbzla 1400: ibhs-25thiaz-bala-betapyee 1401: tolhs-nme35pyr-gly-betapyee 5 1402: bhs-25oxaz-gly-betahdcph 1403: bhs-25oxaz-gly-beta4bph 1404: ibhs-24thiaz-bala-beta4bph1397: phhs-me25thioph-gly-betadcph 1398: bhs-24thioph-bala-betapym 1399: tolhs-24thioph-gly-aspbzla 1400: ibhs-25thiaz-bala-betapyee 1401: tolhs-nme35pyr-gly-betapyee 5 1402: bhs-25oxaz-gly-betahdcph 1403: bh 25oxaz-gly-beta4bph 1404: ibhs-24thiaz-bala-beta4bph
1405: bim-ithiadiaz-bala-betapy1405: bim-ithiadiaz-bala-betapy
1406 : ibhs-nme35pyr-bala-betabdimo1406: ibhs-nme35pyr-bala-betabdimo
1407: 2py-25thiaz-gly-aspibua1407: 2py-25thiaz-gly aspibua
1010
1408: bhs-25oxaz-ala-betabpy1408: bhs-25oxaz-ala-betabpy
1409: bhs-oxadiaz-gly-betahbcph1409: bras-oxadiaz-gly-betahbcph
1410: bim-me25thioph-leu-betaph1410: bim-me25thioph-leu-betaph
1411: bhs-24thiaz-bala-betadito1411: bras-24thiaz-bala-betadito
1412: dhim-24oxaz-gly-betadcph 15 1413 : tolhs-ithiadiaz-gly-betahcbph1412: dhim-24oxaz-gly-betadcph 15 1413: tolhs-ithiadiaz-gly-betahcbph
1414: bhs-nme35pyr-leu-betapy1414: bhs-nme35pyr-leu-betapy
1415: tolhs-nme35pyr-bala-betaol1415: tolhs-nme35pyr-bala-betaol
1416: ibhs-oxadiaz-gly-betapych1416: ibhs-oxadiaz-gly-betapych
1417 : tolhs-nme35pyr-gly-betacthioph 20 1418: tolhs-nme35pyr-bala-aspbzla1417: tolhs-nme35pyr-gly-betacthioph 20 1418: tolhs-nme35pyr-bala-aspbzla
1419 : 2py-me24thioph-gly-beta34meoph1419: 2py-me24thioph-gly-beta34meoph
1420: dhpyrr-24thiaz-gly-betadcph1420: dhpyrr-24thiaz-gly-betadcph
1421: bhs-24thiaz-gly-betaet1421: bhs-24thiaz-gly-betaet
1422: bim-24thiaz-nmala-betadcph1422: bim-24thiaz-nmala-betadcph
1423: ibhs-nme35pyr-gly-betambiph1423: ibhs-nme35pyr-gly-betambiph
25 1424: tolhs-ithiadiaz-gly-ibsdap25 1424: tolhs-ithiadiaz-gly-ibsdap
1425 : tolhs-25oxaz-gly-betacthioph1425: tolhs-25oxaz-gly-betacthioph
1426 : tolhs-24thioph-gly-betadhbfu1426: tolhs-24thioph-gly-betadhbfu
1427: bhs-me25thiaz-ala-betaph1427: bhs-me25thiaz-ala-betaph
1428: phhs-25thiaz-bala-betameph 30 1429: bhs-24thiaz-ala-beta34dcph1428: phhs-25thiaz-bala-betameph 30 1429: bhs-24thiaz-ala-beta34dcph
1430: ibhs-nme35pyr-bala-betapyr1430: ibhs-nme35pyr-bala-betapyr
1431: 2py-me24thioph-leu-betapy1431: 2py-me24thioph-leu-betapy
1432: bhs-24thiaz-bala-betafu21432: bhs-24thiaz-bala-betafu2
1433 : bhs-ithiadiaz-bala-betaamibe 35 1434: bhs-25methiaz-ala-betadmoph1433: bhs-ithiadiaz-bala-betaamibe 35 1434: bhs-25methiaz-ala-betadmoph
1435: bim-me24thiaz-gly-zdap1435: bim-me24thiaz-gly-zdap
1436: bim-25methiaz-bala-csdap1436: bim-25methiaz-bala-csdap
1437 : 2py-me25oxaz-ala-beta34meoph1437: 2py-me25oxaz-ala-beta34meoph
1438: phhs-oxadiaz-gly-ibsdap1438: phhs-oxadiaz-gly-ibsdap
1439: phhs-25thiaz-bala-betabph1439: phhs-25thiaz-bala-betabph
40 1440: bhs-25methiaz-ala-beta34dcph40 1440: bhs-25methiaz-ala-beta34dcph
1441 : tolhs-oxadiaz-bala-betapyee1441: tolhs-oxadiaz-bala-betapyee
1442 : ibhs-oxadiaz-bala-betaanaphth1442: ibhs-oxadiaz-bala-betaanaphth
1443 : tolhs-25oxaz-bala-betathiobe1443: tolhs-25oxaz-bala-betathiobe
1444: 2pmhs-24thiaz-bala-beta4bph 45 1445: ibhs-ithiadiaz-gly-ibsdap1444: 2 pmhs-24thiaz-bala-beta4bph 45 1445: ibhs-ithiadiaz-gly-ibsdap
1446: phhs-24thioph-bala-aspaba1446: phhs-24thioph-bala-aspaba
1447 : tolhs-24thiaz-bala-betaamibe 1448 : bhs-25methiaz-gly-betaanaphth 1449: bhs-24thioph-gly-betaph 1450: bhs-oxadiaz-bala-betahb 1451: bhs-52thiaz-gly-betapy 1452: ibhs-oxadiaz-bala-betafluo 1453: phhs-nme35pyr-bala-betadtrif 1454: phhs-25oxaz-bala-betapyr 1455: bhs-25methiaz-bala-betaipr 1456: ibhs-24thiaz-gly-beta35dbph 1457: ibhs-25thiaz-gly-psdapch1447: tolhs-24thiaz-bala-betaamibe 1448: bhs-25methiaz-gly-betaanaphth 1449: bhs-24thioph-gly-betaph 1450: bhs-oxadiaz-bala-betahb 1451: bhs-52thiaz-gly-betapy 1452: ibhs-oxadiaz-bala-betafluo 1453: phhs-nme35pyr -bala-betadtrif 1454: phhs-25oxaz-bala-betapyr 1455: bhs-25methiaz-bala-betaipr 1456: ibhs-24thiaz-gly-beta35dbph 1457: ibhs-25thiaz-gly-psdapch
10 1458: bhs-24thiaz-bala-betatbuph 1459 : tolhs-ithiadiaz-bala-betadmoph 1460: ibhs-25thiaz-gly-betaftrif 1461: bhs-25methiaz-ala-betafphe 1462: sabhs-42pym-gly-betapy10 1458: bhs-24thiaz-bala-betatbuph 1459: tolhs-ithiadiaz-bala-betadmoph 1460: ibhs-25thiaz-gly-betaftrif 1461: bhs-25methiaz-ala-betafphe 1462: sabhs-42pym-gly-betapy
15 1463: phhs-me25thiaz-bala-zdap 1464: phhs-24thiaz-gly-betaibph 1465: 2py-25methiaz-gly-betacthioph 1466: dhim-25thioph-gly-betapy 1467: bim-me24thiaz-bala-psdap15 1463: phhs-me25thiaz-bala-zdap 1464: phhs-24thiaz-gly-betaibph 1465: 2py-25methiaz-gly-betacthioph 1466: dhim-25thioph-gly-betapy 1467: bim-me24thiaz-bala-psdap
20 1468 : ibhs-24thioph-gly-betabnaphth 1469 : tolhs-25methiaz-bala-betaoxope 1470: sabhs-25oxaz-bala-betameph 1471 : tolhs-25methiaz-gly-beta34dcph 1472 : ibhs-oxadiaz-bala-betathiome 1473 : dhim-42pym-gly-betahdcph20 1468: ibhs-24thioph-gly-betabnaphth 1469: tolhs-25methiaz-bala-betaoxope 1470: sabhs-25oxaz-bala-betameph 1471: tolhs-25methiaz-gly-beta34dcph 1472: ibhs-oxadiaz-bala-betathiome 1473: 42pym-gly-betahdcph
25 1474: 2py-25thiaz-leu-betapy 1475: ibhs-25thiaz-gly-betah35dc 1476: bhs-25oxaz-bala-betathiobe 1477: bhs-oxadiaz-nmgly-betamesu 1478: bhs-oxadiaz-bala-betaol25 1474: 2py-25thiaz-leu-betapy 1475: ibhs-25thiaz-gly-betah35dc 1476: bhs-25oxaz-bala-betathiobe 1477: bhs-oxadiaz-nmgly-betamesu 1478: bhs-oxadiaz-bala-betaol
30 1479: phhs-oxadiaz-gly-aspbzla 1480: hs-25thiaz-gly-betapy 1481 : tolhs-ithiadiaz-bala-betaomebendi 1482 : tolhs-25methiaz-bala-beta4bph 1483: phhs-ithiadiaz-bala-csdap30 1479: phhs-oxadiaz-gly-aspbzla 1480: hs-25thiaz-gly-betapy 1481: tolhs-ithiadiaz-bala-betaomebendi 1482: tolhs-25methiaz-bala-beta4bph 1483: phhs-ithiadiaz-bala-csdap
35 1484: bim-25py-gly-zdap 1485: ibhs-24thioph-gly-betafbph 1486: impy-25methiaz-gly-betambiph 1487 : 2pmhs-25thiaz-bala-betamethioph 1488: tolhs-24 hioph-bala-betafluo 1489: ibhs-ithiadiaz-gly-aspaba35 1484: bim-25py-gly-zdap 1485: ibhs-24thioph-gly-betafbph 1486: impy-25methiaz-gly-betambiph 1487: 2 pmhs-25thiaz-bala-betamethioph 1488: tolhs-24 hioph-bala-betafluo 1489: ibhs -ithiadiaz-gly-aspaba
40 1490: phhs-25methiaz-bala-betacph 1491: bhs-nme35pyr-gly-betatos 1492 : dimethpym-25thiaz-gly-betadcph 1493: ibhs-oxadiaz-bala-betaimid 1494 : tolhs-24thioph-bala-betaoxope40 1490: phhs-25methiaz-bala-betacph 1491: bhs-nme35pyr-gly-betatos 1492: dimethpym-25thiaz-gly-betadcph 1493: ibhs-oxadiaz-bala-betaimid 1494: tolhs-24thioph-bala-betaoxope
45 1495: bhs-nme35pyr-bala-betamethioph 1496: 2py-me24thiaz-leu-betaph 1497: tolhs-nme35pyr-bala-betahni 1498 : phhs-oxadiaz-gly-betacthioph 1499: bhs-25thiaz-gly-busu2be 1500: ibhs-oxadiaz-bala-betaipro 1501: tolhs-25thiaz-bala-betadmoph 1502: bhs-25methiaz-ala-betainyl 1503: bhs-25oxaz-bala-betahcbph 1504 : ibhs-ithiadiaz-gly-betacthioph 1505 : tolhs-nme35pyr-bala-betaomebendi 1506: phhs-24thioph-bala-betaipr 1507 : tolhs-25methiaz-gly-betaoxaz45 1495: bhs-nme35pyr-bala-betamethioph 1496: 2py-me24thiaz-leu-betaph 1497: tolhs-nme35pyr-bala-betahni 1498: phhs-oxadiaz-gly-betacthioph 1499: bhs-25thiaz-gly-busu2be 1500: ibhs-oxadiaz-bala-betaipro 1501: tolhs-25thiaz-bala-betadmoph 1502: bhs-25methiaz-ala-betainyl 1503: bhs-25oxaz -bala-betahcbph 1504: ibhs-ithiadiaz-gly-betacthioph 1505: tolhs-nme35pyr-bala-betaomebendi 1506: phhs-24thioph-bala-betaipr 1507: tolhs-25methiaz-gly-betaoxaz
10 1508: tolhs-nme35pyr-bala-betaamibe 1509: bhs-25thiaz-bala-betaheph 1510: ibhs-24thioph-gly-asppha 1511: phhs-oxadiaz-bala-betadmoph 1512: 2py-25thiaz-ala-betameph10 1508: tolhs-nme35pyr-bala-betaamibe 1509: bhs-25thiaz-bala-betaheph 1510: ibhs-24thioph-gly-asppha 1511: phhs-oxadiaz-bala-betadmoph 1512: 2py-25thiaz-ala-betameph
15 1513: bhs-thiadiaz-ala-zdap 1514: bhs-24thiaz-bala-betafph 1515: 2pmhs-25thiaz-bala-betabmph 1516: bhs-24thioph-bala-betafu2 1517: bim-me25thioph-bala-zdap15 1513: bhs-thiadiaz-ala-zdap 1514: bhs-24thiaz-bala-betafph 1515: 2 pmhs-25thiaz-bala-betabmph 1516: bhs-24thioph-bala-betafu2 1517: bim-me25thioph-bala-zdap
20 1518: bhs-25methiaz-gly-aspibua20 1518: bhs-25methiaz-gly-aspibua
1519 : bhs-nme35pyr-nmgly-beta34dcph 1520: gua-24thiaz-gly-betafu2 1521: phhs-oxadiaz-gly-betambiph 1522: bhs-24thioph-bala-aspaba 1523: phhs-24thiaz-gly-beta35dbph1519: bhs-nme35pyr-nmgly-beta34dcph 1520: gua-24thiaz-gly-betafu2 1521: phhs-oxadiaz-gly-betambiph 1522: bhs-24thioph-bala-aspaba 1523: phhs-24thiaz-gly-beta35dbph
25 1524: ibhs-24thioph-gly-betaipro 1525: bhs-ithiadiaz-bala-psdapch 1526: bhs-25oxaz-gly-betamethioph 1527: bhs-25thiaz-ala-beta34dcph 1528: bhs-ithiadiaz-bala-betaipro25 1524: ibhs-24thioph-gly-betaipro 1525: bhs-ithiadiaz-bala-psdapch 1526: bhs-25oxaz-gly-betamethioph 1527: bhs-25thiaz-ala-beta34dcph 1528: bhs-ithiadiaz-bala-betaipro
30 1529: bhs-25oxaz-gly-betah35dc 1530: gua-25thioph-gly-betah35dc 1531 : bhs-25oxaz-gly-betabph 1532 : bhs-oxadiaz-bala-betaphethio 1533: impy-24thiaz-bala-psdap30 1529: bhs-25oxaz-gly-betah35dc 1530: gua-25thioph-gly-betah35dc 1531: bhs-25oxaz-gly-betahph 1532: bhs-oxadiaz-bala-betaphethio 1533: impy-24thiaz-bala-psdap
35 1534: bhs-25methiaz-gly-betaol 1535: phhs-25oxaz-bala-betapytb 1536: tolhs-25oxaz-bala-zdaptb 1537 : tolhs-nme35pyr-bala-betadcphee 1538: bgua-25thioph-gly-betameph 1539: bhs-oxadiaz-gly-betathio335 1534: bhs-25methiaz-gly-betaol 1535: phhs-25oxaz-bala-betapytb 1536: tolhs-25oxaz-bala-zdaptb 1537: tolhs-nme35pyr-bala-betadcphee 1538: bgua-25thioph-gly-betameph 1539: bgua oxadiaz-gly-betathio3
40 1540: ibhs-25thiaz-gly-betahc 1541: gua-24thiaz-gly-betathioph 1542 : 2py-53pyrazo-bala-betapy 1543 : phhs-ithiadiaz-gly-beta34dcph 1544: dhim-25thioph-ala-betadcph40 1540: ibhs-25thiaz-gly-betahc 1541: gua-24thiaz-gly-betathioph 1542: 2py-53pyrazo-bala-betapy 1543: phhs-ithiadiaz-gly-beta34dcph 1544: dhim-25thioph-ala-betadcph
45 1545: phhs-25thiaz-gly-betapy45 1545: phhs-25thiaz-gly-betapy
1546: ibhs-25thiaz-bala-betah35dc 1547: phhs-25methiaz-gly-psdap 1548: bhs-oxadiaz-gly-betafluo1546: ibhs-25thiaz-bala-betah35dc 1547: phhs-25methiaz-gly-psdap 1548: bhs-oxadiaz-gly-betafluo
1549: impy-25thiaz-gly-betacbph1549: impy-25thiaz-gly-betacbph
1550: 2py-24im-bala-zdap1550: 2py-24im-bala-zdap
1551: tolhs-oxadiaz-bala-betahb 5 1552: phhs-25oxaz-bala-betaoxope1551: tolhs-oxadiaz-bala-betahb 5 1552: phhs-25oxaz-bala-betaoxope
1553: tolhs-25thiaz-gly-betaipr1553: tolhs-25thiaz-gly-betaipr
1554: ibhs-oxadiaz-bala-csdap1554: ibhs-oxadiaz-bala-csdap
1555: ibhs-24thiaz-gly-betampy1555: ibhs-24thiaz-gly-betampy
1556: bim-thiadiaz-gly-betadcph1556: bim-thiadiaz-gly-betadcph
1557 : 2py-me24thioph-bala-betadcph1557: 2py-me24thioph-bala-betadcph
1010
1558: bhs-ithiadiaz-nmgly-betadhbfu1558: bhs-ithiadiaz-nmgly-betadhbfu
155 : phhs-25oxaz-bala-betathioph155: phhs-25oxaz-bala-betathioph
1560: ibhs-25oxaz-bala-betaol1560: ibhs-25oxaz-bala-betaol
1561: bhs-nme35pyr-gly-betaoxope1561: bhs-nme35pyr-gly-betaoxope
1562 : phhs-ithiadiaz-bala-betathiobe 15 1563: 2py-25methiaz-leu-zdap1562: phhs-ithiadiaz-bala-betathiobe 15 1563: 2py-25methiaz-leu-zdap
1564: tolhs-25thiaz-gly-betafu21564: tolhs-25thiaz-gly-betafu2
1565: phhs-24thioph-bala-betahni1565: phhs-24thioph-bala-betahni
1566 : ibhs-nme35pyr-gly-betatbuph1566: ibhs-nme35pyr-gly-betatbuph
1567 : ibhs-ithiadiaz-gly-betapbiph 20 1568: tolhs-oxadiaz-gly-betatos1567: ibhs-ithiadiaz-gly-betapbiph 20 1568: tolhs-oxadiaz-gly-betatos
1569: bim-triaz-bala-betapy1569: bim-triaz-bala-betapy
1570: tolhs-25oxaz-bala-betafphe1570: tolhs-25oxaz-bala-betafphe
1571 : bhs-ithiadiaz-nmgly-betathio31571: bhs-ithiadiaz-nmgly-betathio3
1572: 2py-me25thioph-gly-zdap1572: 2py-me25thioph-gly-zdap
1573: tolhs-25oxaz-gly-csdap1573: tolhs-25oxaz-gly-csdap
25 1574: 2py-thiadiaz-gly-psdap25 1574: 2py-thiadiaz-gly-psdap
1575: bhs-52thiaz-gly-betainyl1575: bhs-52thiaz-gly-betainyl
1576: phhs-ithiadiaz-gly-betahmo1576: phhs-ithiadiaz-gly-betahmo
1577 : ibhs-25thiaz-gly-betathiome1577: ibhs-25thiaz-gly-betathiome
1578: 2py-oxadiaz-bala-betapy 30 1579: 2pmhs-24thiaz-bala-betathioph1578: 2py-oxadiaz-bala-betapy 30 1579: 2 pmhs-24thiaz-bala-betathioph
1580: bim-25thiaz-bala-betahc1580: bim-25thiaz-bala-betahc
1581: bim-triaz-leu-psdap1581: bim-triaz-leu-psdap
1582 : phhs-25methiaz-bala-aspibua1582: phhs-25methiaz-bala-aspibua
1583 : bhs-me24thioph-bala-beta34meoph 35 1584: phhs-25oxaz-gly-betadcphtb1583: bhs-me24thioph-bala-beta34meoph 35 1584: phhs-25oxaz-gly-betadcphtb
1585 : tolhs-ithiadiaz-gly-beta4bph1585: tolhs-ithiadiaz-gly-beta4bph
1586 : ibhs-25oxaz-bala-betamethioph1586: ibhs-25oxaz-bala-betamethioph
1587: phhs-ithiadiaz-gly-betah35dc1587: phhs-ithiadiaz-gly-betah35dc
1588: bhs-25methiaz-gly-betahdbph1588: bhs-25methiaz-gly-betahdbph
1589: gua-25thiaz-gly-betahdbph1589: gua-25thiaz-gly-betahdbph
40 1590: 4pmhs-24thiaz-bala-betameph40 1590: 4 pmhs-24thiaz-bala-betameph
1591: bhs-ithiadiaz-gly-betainyl1591: bhs-ithiadiaz-gly-betainyl
1592: tolhs-25oxaz-bala-betah35dc1592: tolhs-25oxaz-bala-betah35dc
1593: 2py-25fur-bala-psdap1593: 2py-25fur-bala-psdap
1594: nmhs-24thiaz-gly-psdap 45 1595: phhs-25methiaz-bala-betadcphee1594: nmhs-24thiaz-gly-psdap 45 1595: phhs-25methiaz-bala-betadcphee
1596: ibhs-25methiaz-bala-betabph1596: ibhs-25methiaz-bala-betabph
1597: ibhs-oxadiaz-bala-betabph 1598 : ibhs-ithiadiaz-bala-betahbcph1597: ibhs-oxadiaz-bala-betabph 1598: ibhs-ithiadiaz-bala-betahbcph
1599: 2py-triaz-ala-zdap1599: 2py-triaz-ala-zdap
1600: bhs-nme35pyr-nmgly-beta3quin1600: bhs-nme35pyr-nmgly-beta3quin
1601: dhim-25thioph-ala-zdap 5 1602: bhs-me24oxaz-leu-beta34meoph1601: dhim-25thioph-ala-zdap 5 1602: bhs-me24oxaz-leu-beta34meoph
1603: phhs-25methiaz-gly-aspaba1603: phhs-25methiaz-gly-aspaba
1604: bhs-nme35pyr-bala-betadtrif1604: bras-nme35pyr-bala-betadtrif
1605: tolhs-24thioph-bala-betadtrif1605: tolhs-24thioph-bala-betadtrif
1606: bhs-25methiaz-bala-betahb1606: bras-25methiaz-bala-betahb
1607: 2py-24thiaz-ala-betainyl1607: 2py-24thiaz-ala-betainyl
10 1608: bhs-25thiaz-gly-betaph10 1608: bhs-25thiaz-gly-betaph
1609 : tolhs-oxadiaz-bala-betabediox1609: tolhs-oxadiaz-bala-betabediox
1610: bhs-oxadiaz-bala-betaoxope1610: bras-oxadiaz-bala-betaoxope
1611 : bhs-25thiaz-nmgly-betaanaphth1611: bhs-25thiaz-nmgly-betaanaphth
1612: phhs-24thioph-gly-betadmph 15 1613: phhs-25methiaz-gly-betainyl1612: phhs-24thioph-gly-betadmph 15 1613: phhs-25methiaz-gly-betainyl
1614: gua-24thiaz-gly-betadcph1614: gua-24thiaz-gly-betadcph
1615 : bhs-24thioph-bala-betadcphee1615: bras-24thioph-bala-betadcphee
1616: phhs-ithiadiaz-gly-betabph1616: phhs-ithiadiaz-gly-betabph
1617: bhs-thiadiaz-ala-betapy 20 1618: bim-me25oxaz-leu-psdap1617: bhs-thiadiaz-ala-betapy 20 1618: bim-me25oxaz-leu-psdap
1619: 2py-me24thioph-bala-betaph1619: 2py-me24thioph-bala-betaph
1620: tolhs-nme35pyr-bala-betabediox1620: tolhs-nme35pyr-bala-betabediox
1621 : bhs-25methiaz-ala-beta34meoph1621: bhs-25methiaz-ala-beta34meoph
1622 : tolhs-ithiadiaz-gly-betadmoph1622: tolhs-ithiadiaz-gly-betadmoph
1623: bhs-24thiaz-nmala-betapy1623: bhs-24thiaz-nmala-betapy
25 1624: 2py-triaz-leu-betadcph25 1624: 2py-triaz-leu-betadcph
1625 : ibhs-24thioph-bala-betaibph1625: ibhs-24thioph-bala-betaibph
1626: phhs-me25oxaz-ala-betaph1626: phhs-me25oxaz-ala-betaph
1627: gua-24oxaz-gly-betaph1627: gua-24oxaz-gly-betaph
1628: phhs-ithiadiaz-gly-betapych 30 1629: bhs-me24oxaz-leu-zdap1628: phhs-ithiadiaz-gly-betapych 30 1629: bhs-me24oxaz-leu-zdap
1630: ibhs-25thiaz-bala-betamethi1630: ibhs-25thiaz-bala-betamethi
1631: bim-42oxaz-leu-psdap1631: bim-42oxaz-leu-psdap
1632: bhs-25thiaz-hphe-betameph1632: bras-25thiaz-hphe-betameph
1633: bhs-nme35pyr-nmgly-betabpy 35 1634: 2pmhs-25thiaz-bala-betal3bendi1633: bhs-nme35pyr-nmgly-betabpy 35 1634: 2 pmhs-25thiaz-bala-betal3bendi
1635: ibhs-ithiadiaz-gly-zdapch1635: ibhs-ithiadiaz-gly-zdapch
1636: tolhs-oxadiaz-gly-psdapee1636: tolhs-oxadiaz-gly-psdapee
1637: bhs-25oxaz-ala-betainyl1637: bhs-25oxaz-ala-betainyl
1638: tolhs-25thiaz-bala-suabu1638: tolhs-25thiaz-bala-suabu
1639: bim-24thiaz-leu-betadcph1639: bim-24thiaz-leu-betadcph
40 1640 : bhs-24thioph-gly-beta34dcph40 1640: bhs-24thioph-gly-beta34dcph
1641: tolhs-oxadiaz-gly-aspaba1641: tolhs-oxadiaz-gly-aspaba
1642 : phhs-25thiaz-gly-betathiome1642: phhs-25thiaz-gly-betathiome
1643: phhs-24thioph-bala-psdaptb1643: phhs-24thioph-bala-psdaptb
1644 : phhs-nme35pyr-bala-betabediox 45 1645: tolhs-oxadiaz-gly-betahcbph1644: phhs-nme35pyr-bala-betabediox 45 1645: tolhs-oxadiaz-gly-betahcbph
1646 : bhs-ithiadiaz-bala-betaomebendi1646: bhs-ithiadiaz-bala-betaomebendi
1647: phhs-24thioph-bala-betahph 1648: 2py-me25thioph-ala-psdap1647: phhs-24thioph-bala-betahph 1648: 2py-me25thioph-ala-psdap
1649: 2py-24thiaz-leu-betapy1649: 2py-24thiaz-leu-betapy
1650: 2py-25oxaz-gly-aspibua1650: 2py-25oxaz-gly-aspibua
1651: sabhs-24thiaz-gly-betapy 5 1652: phhs-25oxaz-gly-betahbcph1651: sabhs-24thiaz-gly-betapy 5 1652: phhs-25oxaz-gly-betahbcph
1653 : tolhs-25methiaz-bala-betabph1653: tolhs-25methiaz-bala-betabph
1654: bhs-ithiadiaz-bala-aspibua1654: bras-ithiadiaz-bala-aspibua
1655: dhim-26py-gly-betaoxaz1655: dhim-26py-gly-betaoxaz
1656: ibhs-oxadiaz-gly-beta4bph1656: ibhs-oxadiaz-gly-beta4bph
1657: bhs-24thiaz-nmgly-beta3quin1657: bhs-24thiaz-nmgly-beta3quin
10 1658: phhs-25methiaz-gly-betabph10 1658: phhs-25methiaz-gly-betabph
1659: tolhs-25methiaz-gly-betathiobe1659: tolhs-25methiaz-gly-betathiobe
1660: bhs-25thiaz-bala-zdapee1660: bras-25thiaz-bala-zdapee
1661: bim-24thiaz-bala-zdap1661: bim-24thiaz-bala-zdap
1662: 2pmhs-42nmeim-ser-psdap 15 1663: phhs-24thiaz-gly-betathio31662: 2 pmhs-42nmeim-ser-psdap 15 1663: phhs-24thiaz-gly-betathio3
1664 : bhs-24thioph-nmgly-betal3bendi1664: bhs-24thioph-nmgly-betal3bendi
1665: phhs-25methiaz-gly-betaheph1665: phhs-25methiaz-gly-betaheph
1666: tolhs-25thiaz-gly-betaet1666: tolhs-25thiaz-gly-betet
1667 : tolhs-me24thioph-ala-betadcph 20 1668: ibhs-25oxaz-bala-betaipr1667: tolhs-me24thioph-ala-betadcph 20 1668: ibhs-25oxaz-bala-betaipr
1669: phhs-me25thioph-ala-zdap1669: phhs-me25thioph-ala-zdap
1670: ibhs-25thiaz-bala-betambiph1670: ibhs-25thiaz-bala-betambiph
1671: tolhs-me25thioph-ala-beta34meoph1671: tolhs-me25thioph-ala-beta34meoph
1672 : ibhs-25thiaz-gly-betaphethio1672: ibhs-25thiaz-gly-betaphethio
1673 : phhs-24thiaz-bala-betaomebendi1673: phhs-24thiaz-bala-betaomebendi
25 1674 : ibhs-24thiaz-gly-beta34meoph25 1674: ibhs-24thiaz-gly-beta34meoph
1675: bim-35fur-bala-betapy1675: bim-35fur-bala-betapy
1676: tolhs-25thiaz-gly-zdapee1676: tolhs-25thiaz-gly-zdapee
1677: ibhs-25oxaz-gly-betatrif1677: ibhs-25oxaz-gly-betatrif
1678: phhs-oxadiaz-gly-betamethioph 30 1679: 2py-thiadiaz-bala-zdap1678: phhs-oxadiaz-gly-betamethioph 30 1679: 2py-thiadiaz-bala-zdap
1680: bhs-24thioph-bala-zdapch1680: bhs-24thioph-bala-zdapch
1681: bhs-25methiaz-bala-betafu21681: bhs-25methiaz-bala-betafu2
1682: ibhs-oxadiaz-gly-psdap1682: ibhs-oxadiaz-gly-psdap
1683: bhs-oxadiaz-gly-betapyee 35 1684: bhs-me24thioph-gly-zdap1683: bhs-oxadiaz-gly-betapyee 35 1684: bhs-me24thioph-gly-zdap
1685: bim-me25oxaz-ala-zdap1685: bim-me25oxaz-ala-zdap
1686 : bhs-25methiaz-gly-betaomebendi1686: bhs-25methiaz-gly-betaomebendi
1687: tolhs-25thiaz-bala-betahb1687: tolhs-25thiaz-bala-betahb
1688: 2py-24thioph-bala-beta34dcph1688: 2py-24thioph-bala-beta34dcph
1689: ibhs-oxadiaz-bala-betapych1689: ibhs-oxadiaz-bala-betapych
40 1690: ibhs-24thioph-gly-betafu240 1690: ibhs-24thioph-gly-betafu2
1691: bhs-25oxaz-ala-beta3quin1691: bhs-25oxaz-ala-beta3quin
1692 : bhs-24thioph-bala-betabediox1692: bhs-24thioph-bala-betabediox
1693: phhs-nme35pyr-gly-betapy1693: phhs-nme35pyr-gly-betapy
1694: ibhs-ithiadiaz-gly-betamesu 45 1695: bhs-25methiaz-gly-betabediox1694: ibhs-ithiadiaz-gly-betamesu 45 1695: bhs-25methiaz-gly-betabediox
1696: phhs-25thiaz-gly-betafu21696: phhs-25thiaz-gly-betafu2
1697: 2py-24thiaz-bala-betaheph 1698: phhs-oxadiaz-gly-asppha1697: 2py-24thiaz-bala-betaheph 1698: phhs-oxadiaz-gly-asppha
1699: ibhs-ithiadiaz-bala-psdap1699: ibhs-ithiadiaz-bala-psdap
1700: thpym-25methiaz-bala-psdap1700: thpym-25methiaz-bala-psdap
1701 : tolhs-25oxaz-bala-betabenfu 5 1702: ibhs-ithiadiaz-gly-betathio31701: tolhs-25oxaz-bala-betabenfu 5 1702: ibhs-ithiadiaz-gly-betathio3
1703: bhs-25methiaz-gly-betampy1703: bhs-25methiaz-gly-betampy
1704: bim-52thiaz-gly-betameph1704: bim-52thiaz-gly-betameph
1705: tolhs-nme35pyr-gly-beta23meoph1705: tolhs-nme35pyr-gly-beta23meoph
1706 : bhs-ithiadiaz-bala-betaftrif1706: bras-ithiadiaz-bala-betaftrif
1707: bhs-25oxaz-gly-betadmoph1707: bhs-25oxaz-gly-betadmoph
10 1708: phhs-24thiaz-gly-betainyl10 1708: phhs-24thiaz-gly-betainyl
1709: ibhs-25thiaz-gly-betaanaphth1709: ibhs-25thiaz-gly-betaanaphth
1710 : phhs-ithiadiaz-bala-betaphethio1710: phhs-ithiadiaz-bala-betaphethio
1711 : phhs-25thiaz-bala-betahdcph1711: phhs-25thiaz-bala-betahdcph
1712: 4pmhs-25oxaz-gly-betapy 15 1713: bhs-53pyrazo-ala-betapy1712: 4 pmhs-25oxaz-gly-betapy 15 1713: bhs-53pyrazo-ala-betapy
1714: phhs-nme35pyr-bala-betathioph1714: phhs-nme35pyr-bala-betathioph
1715: bhs-nme35pyr-nmgly-betamesu1715: bhs-nme35pyr-nmgly-betamesu
1716: phhs-25oxaz-gly-betampy1716: phhs-25oxaz-gly-betampy
1717: 2py-25oxaz-bala-betaphethioa 20 1718: bhs-25methiaz-bala-betafu31717: 2py-25oxaz-bala-betaphethioa 20 1718: bhs-25methiaz-bala-betafu3
1719: phhs-me24oxaz-leu-betadcph1719: phhs-me24oxaz-leu-betadcph
1720: bhs-25thiaz-ala-ibsdap1720: bhs-25thiaz-ala-ibsdap
1721: bhs-ithiadiaz-gly-betabmph1721: bhs-ithiadiaz-gly-betabmph
1722 : bhs-ithiadiaz-bala-betadmoph1722: bhs-ithiadiaz-bala-betadmoph
1723: phhs-25thiaz-gly-betatbuph1723: phhs-25thiaz-gly-betatbuph
25 1724: 2py-42pym-ala-psdap25 1724: 2py-42pym-ala-psdap
1725: ibhs-nme35pyr-gly-betaoxaz1725: ibhs-nme35pyr-gly-betaoxaz
1726: phhs-24thioph-bala-betafu31726: phhs-24thioph-bala-betafu3
1727: phhs-25oxaz-bala-betapbiph1727: phhs-25oxaz-bala-betapbiph
1728: 2py-me25oxaz-ala-betapy 30 1729: phhs-me24thiaz-gly-betaph1728: 2py-me25oxaz-ala-betapy 30 1729: phhs-me24thiaz-gly-betaph
1730: bhs-25methiaz-nmgly-betaipro1730: bhs-25methiaz-nmgly-betaipro
1731: phhs-me24thiaz-leu-psdap1731: phhs-me24thiaz-leu-psdap
1732: gua-42pym-gly-betaphethio1732: gua-42pym-gly-betaphethio
1733 : bhs-24thioph-gly-betaoxaz 35 1734: bhs-oxadiaz-bala-betahc1733: bhs-24thioph-gly-betaoxaz 35 1734: bhs-oxadiaz-bala-betahc
1735: ibhs-nme35pyr-gly-betainyl1735: ibhs-nme35pyr-gly-betainyl
1736 : tolhs-nme35pyr-bala-psdaptb1736: tolhs-nme35pyr-bala-psdaptb
1737: bhs-oxadiaz-bala-betadmph1737: bras-oxadiaz-bala-betadmph
1738: phhs-ithiadiaz-gly-betafbph1738: phhs-ithiadiaz-gly-betafbph
1739 : phhs-25thiaz-gly-betahcbph1739: phhs-25thiaz-gly-betahcbph
40 1740: tolhs-25oxaz-bala-betaibph40 1740: tolhs-25oxaz-bala-betaibph
1741: tolhs-25oxaz-gly-betapych1741: tolhs-25oxaz-gly-betapych
1742 : bhs-24thiaz-nmgly-betabnaphth1742: bhs-24thiaz-nmgly-betabnaphth
1743: phhs-25methiaz-gly-zdap1743: phhs-25methiaz-gly-zdap
1744: 2py-42nmeim-gly-betaipro 45 1745: bhs-24thioph-bala-betafph1744: 2py-42nmeim-gly-betaipro 45 1745: bhs-24thioph-bala-betafph
1746: ibhs-24thioph-bala-betambiph1746: ibhs-24thioph-bala-betambiph
1747: 2pmhs-42nmeim-gly-betahdcph 1748: 2py-24thiaz-gly-zdap1747: 2 pmhs-42nmeim-gly-betahdcph 1748: 2py-24thiaz-gly-zdap
1749: phhs-oxadiaz-bala-betamethi1749: phhs-oxadiaz-bala-betamethi
1750: bhs-me25thiaz-bala-betaph1750: bhs-me25thiaz-bala-betaph
1751: bhs-triaz-ala-betadcph 5 1752: bhs-25methiaz-bala-betahmofu1751: bhs-triaz-ala-betadcph 5 1752: bhs-25methiaz-bala-betahmofu
1753: bhs-25thiaz-ala-betafphe1753: bhs-25thiaz-ala-betafphe
1754: phhs-oxadiaz-bala-betafluo1754: phhs-oxadiaz-bala-betafluo
1755: phhs-24thiaz-bala-betabenfu1755: phhs-24thiaz-bala-betabenfu
1756: 2py-24thiaz-bala-aspbzla1756: 2py-24thiaz-bala-aspbzla
1757: bhs-24thiaz-ala-psdap1757: bhs-24thiaz-ala-psdap
10 1758: phhs-oxadiaz-gly-betapyee10 1758: phhs-oxadiaz-gly-betapyee
1759: tolhs-25thiaz-bala-betaph1759: tolhs-25thiaz-bala-betaph
1760: ibhs-24thioph-bala-betaheph1760: ibhs-24thioph-bala-betaheph
1761: tolhs-24thioph-bala-zdaptb1761: tolhs-24thioph-bala-zdaptb
1762: tolhs-24thiaz-gly-zdapee 15 1763 : ibhs-ithiadiaz-bala-betaomebendi1762: tolhs-24thiaz-gly-zdapee 15 1763: ibhs-ithiadiaz-bala-betaomebendi
1764 : phhs-ithiadiaz-bala-betamethioph1764: phhs-ithiadiaz-bala-betamethioph
1765 : phhs-nme35pyr-bala-betathiobe1765: phhs-nme35pyr-bala-betathiobe
1766: phhs-25thiaz-bala-betafphe1766: phhs-25thiaz-bala-betafphe
1767: ibhs-25thiaz-bala-beta34dcph 20 1768: phhs-24thiaz-gly-psdaptb1767: ibhs-25thiaz-bala-beta34dcph 20 1768: phhs-24thiaz-gly-psdaptb
1769: tolhs-24thioph-gly-betatos1769: tolhs-24thioph-gly-betatos
1770: gua-26py-gly-betamethi1770: gua-26py-gly-betamethi
1771: bhs-oxadiaz-gly-betahmofu1771: bhs-oxadiaz-gly-betahmofu
1772: impy-42nmeim-gly-betahph1772: impy-42nmeim-gly-betahph
1773 : bhs-24thiaz-bala-betadcphtb1773: bras-24thiaz-bala-betadcphtb
25 1774 : tolhs-ithiadiaz-gly-busu2be25 1774: tolhs-ithiadiaz-gly-busu2be
1775 : bim-me24oxaz-bala-beta34meoph1775: bim-me24oxaz-bala-beta34meoph
1776: tolhs-25methiaz-gly-betafu31776: tolhs-25methiaz-gly-betafu3
1777: tolhs-25oxaz-bala-aspbzla1777: tolhs-25oxaz-bala-aspbzla
1778: bhs-oxadiaz-ala-betacph 30 1779: phhs-ithiadiaz-bala-aspbzla1778: bhs-oxadiaz-ala-betacph 30 1779: phhs-ithiadiaz-bala-aspbzla
1780: ibhs-25thiaz-bala-betaph1780: ibhs-25thiaz-bala-betaph
1781: tolhs-oxadiaz-bala-csdap1781: tolhs-oxadiaz-bala-csdap
1782: ibhs-oxadiaz-gly-betadtrif1782: ibhs-oxadiaz-gly-betadtrif
1783: ibhs-25thiaz-gly-betadito1783: ibhs-25thiaz-gly-betadito
35 1784 : tolhs-25oxaz-bala-suabu35 1784: tolhs-25oxaz-bala-suabu
1785: bhs-ithiadiaz-bala-zdap1785: bhs-ithiadiaz-bala-zdap
1786: bhs-25thioph-gly-psdap1786: bhs-25thioph-gly-psdap
1787: 2py-24im-ala-zdap1787: 2py-24im-ala-zdap
1788: 2pmhs-25methiaz-gly-betaph1788: 2 pmhs-25methiaz-gly-betaph
1789: phhs-25oxaz-gly-psdap1789: phhs-25oxaz-gly-psdap
40 1790: bhs-24thioph-bala-betabenfu40 1790: bhs-24thioph-bala-betabenfu
1791: bim-me25oxaz-gly-betadcph1791: bim-me25oxaz-gly-betadcph
1792: bhs-oxadiaz-bala-betahmph1792: bras-oxadiaz-bala-betahmph
1793 : ibhs-ithiadiaz-bala-betafph1793: ibhs-ithiadiaz-bala-betafph
1794 : ibhs-25oxaz-bala-betacph 45 1795: ibhs-25methiaz-gly-betaipro1794: ibhs-25oxaz-bala-betacph 45 1795: ibhs-25methiaz-gly-betaipro
1796: ibhs-24thiaz-gly-betabph1796: ibhs-24thiaz-gly-betabph
1797: 2py-triaz-leu-betapy 1798: tolhs-nme35pyr-gly-zdapch1797: 2py-triaz-leu-betapy 1798: tolhs-nme35pyr-gly-zdapch
1799: bhs-thiadiaz-leu-betadcph1799: bras-thiadiaz-leu-betadcph
1800 : tolhs-ithiadiaz-bala-beta34dcph1800: tolhs-ithiadiaz-bala-beta34dcph
1801: phhs-25oxaz-bala-betampy 5 1802: tolhs-nme35pyr-gly-betabediox1801: phhs-25oxaz-bala-betampy 5 1802: tolhs-nme35pyr-gly-betabediox
1803: phhs-24thiaz-gly-betabenfu1803: phhs-24thiaz-gly-betabenfu
1804 : ibhs-24thioph-gly-betaanaphth1804: ibhs-24thioph-gly-betaanaphth
1805 : ibhs-24thiaz-bala-betabthioph1805: ibhs-24thiaz-bala-betabthioph
1806: bhs-24thiaz-gly-betameph1806: bhs-24thiaz-gly-betameph
1807: bhs-24thioph-bala-betaph1807: bras-24thioph-bala-betaph
1010
1808: ur-25oxaz-bala-zdap1808: ur-25oxaz-bala-zdap
1809: phhs-25thiaz-gly-betadcph1809: phhs-25thiaz-gly-betadcph
1810 : ibhs-24thiaz-gly-betaphethio1810: ibhs-24thiaz-gly-betaphethio
1811: agua-24thioph-gly-psdap1811: agua-24thioph-gly-psdap
1812 : tolhs-24thiaz-bala-betadmoph 15 1813: phhs-nme35pyr-gly-betaheph1812: tolhs-24thiaz-bala-betadmoph 15 1813: phhs-nme35pyr-gly-betaheph
1814: bhs-ithiadiaz-gly-aspbzla1814: bhs-ithiadiaz-gly-aspbzla
1815: cima-25methiaz-bala-psdap1815: cima-25methiaz-bala-psdap
1816: bim-25thiaz-bala-aspaba1816: bim-25thiaz-bala-aspaba
1817 : phhs-oxadiaz-bala-betahcbph 20 1818: phhs-me24thiaz-ala-betadcph1817: phhs-oxadiaz-bala-betahcbph 20 1818: phhs-me24thiaz-ala-betadcph
1819: bim-25oxaz-gly-betafph1819: bim-25oxaz-gly-betafph
1820: bhs-25methiaz-gly-betabenfu1820: bhs-25methiaz-gly-betabenfu
1821: gua-42pym-gly-betabph1821: gua-42pym-gly-betabph
1822: bim-24thioph-bala-asppha1822: bim-24thioph-bala-asppha
1823 : ibhs-oxadiaz-bala-betamethi1823: ibhs-oxadiaz-bala-betamethi
25 1824 : tolhs-24thiaz-bala-betabediox25 1824: tolhs-24thiaz-bala-betabediox
1825: tolhs-25oxaz-bala-psdap1825: tolhs-25oxaz-bala-psdap
1826: ibhs-25thiaz-bala-beta35dbph1826: ibhs-25thiaz-bala-beta35dbph
1827: ibhs-25oxaz-gly-betamesu1827: ibhs-25oxaz-gly-betamesu
1828: ibhs-24thioph-gly-betambiph 30 1829: bhs-25oxaz-gly-betahcbph1828: ibhs-24thioph-gly-betambiph 30 1829: bhs-25oxaz-gly-betahcbph
1830: ibhs-24thioph-gly-betahc1830: ibhs-24thioph-gly-betahc
1831: 2py-25methiaz-gly-asppha1831: 2py-25methiaz-gly-asppha
1832: phhs-oxadiaz-gly-betacbph1832: phhs-oxadiaz-gly-betacbph
1833 : ibhs-ithiadiaz-bala-betaipro 3 1834: bhs-25thiaz-ala-betacthioph1833: ibhs-ithiadiaz-bala-betaipro 3 1834: bhs-25thiaz-ala-betacthioph
1835: phhs-25thiaz-gly-aspibua1835: phhs-25thiaz-gly-aspibua
1836 : ibhs-25methiaz-bala-betamesu1836: ibhs-25methiaz-bala-betamesu
1837: bim-42nmeim-bala-betabediox1837: bim-42nmeim-bala-betabediox
1838 : tolhs-me25thioph-gly-betadcph1838: tolhs-me25thioph-gly-betadcph
1839 : ibhs-25methiaz-bala-betafbph1839: ibhs-25methiaz-bala-betafbph
40 1840: phhs-25oxaz-gly-beta35dbph40 1840: phhs-25oxaz-gly-beta35dbph
1841: phhs-24thioph-bala-betaet1841: phhs-24thioph-bala-betet
1842 : ibhs-25oxaz-gly-betadcphee1842: ibhs-25oxaz-gly-betadcphee
1843: phhs-25oxaz-gly-betadtrif1843: phhs-25oxaz-gly-betadtrif
1844: hs-42nmeim-bala-zdap 45 1845: bim-25methiaz-gly-betaibph1844: hs-42nmeim-bala-zdap 45 1845: bim-25methiaz-gly-betaibph
1846: bim-thiadiaz-ala-betapy1846: bim-thiadiaz-ala-betapy
1847: 2py-me24im-ala-betapy 1848: bhs-24thiaz-gly-betamethioph 1849 : tolhs-24thiaz-gly-beta23meoph 1850: tolhs-nme35pyr-bala-zdaptb 1851: ibhs-nme35pyr-gly-betah35dc 1852: bhs-25thiaz-gly-betahph 1853: bhs-25thiaz-bala-betatbuph 1854: ur-24thioph-gly-betadcph 1855: tolhs-me25thiaz-gly-psdap 1856: ibhs-24thiaz-gly-betafu2 1857 : bhs-ithiadiaz-gly-betathiobe1847: 2py-me24im-ala-betapy 1848: bhs-24thiaz-gly-betamethioph 1849: tolhs-24thiaz-gly-beta23meoph 1850: tolhs-nme35pyr-bala-zdaptb 1851: ibhs-nme35pyr-gly-betah35dc 1852: bhs-25thiaz-gly-betahph 2553iaz -bala-betatbuph 1854: ur-24thioph-gly-betadcph 1855: tolhs-me25thiaz-gly-psdap 1856: ibhs-24thiaz-gly-betafu2 1857: bhs-ithiadiaz-gly-betathiobe
10 1858: bim-25fur-bala-betapy 1859: phhs-25thiaz-gly-betahmph 1860: tolhs-nme35pyr-bala-betadbph 1861: ibhs-oxadiaz-bala-betamesu 1862: ibhs-25oxaz-bala-betabediox10 1858: bim-25fur-bala-betapy 1859: phhs-25thiaz-gly-betahmph 1860: tolhs-nme35pyr-bala-betadbph 1861: ibhs-oxadiaz-bala-betamesu 1862: ibhs-25oxaz-bala-betabediox
15 1863 : tolhs-oxadiaz-bala-betabnaphth 1864: bhs-oxadiaz-bala-zdapee 1865: ibhs-24thiaz-bala-betafph 1866 : tolhs-25methiaz-bala-betaibph 1867: bhs-24thioph-gly-betatrif15 1863: tolhs-oxadiaz-bala-betabnaphth 1864: bhs-oxadiaz-bala-zdapee 1865: ibhs-24thiaz-bala-betafph 1866: tolhs-25methiaz-bala-betaibph 1867: bhs-24thioph-gly-betatrif
20 1868: 3pmhs-42nmeim-bala-zdap20 1868: 3 pmhs-42nmeim-bala-zdap
1869 : phhs-nme35pyr-gly-betathioph 1870: tolhs-nme35pyr-bala-busu2be 1871: bhs-24thiaz-gly-betaoxope 1872: tolhs-24thiaz-gly-betatrif 1873: bhs-25methiaz-gly-betahmo1869: phhs-nme35pyr-gly-betathioph 1870: tolhs-nme35pyr-bala-busu2be 1871: bhs-24thiaz-gly-betaoxope 1872: tolhs-24thiaz-gly-betatrif 1873: bhs-25methiaz-gly-betahmo
25 1874: tolhs-oxadiaz-gly-betahph 1875: phhs-ithiadiaz-gly-zdaptb 1876: bim-42nmeim-bala-betahmofu 1877: 2py-thiadiaz-gly-zdap 1878: bhs-ithiadiaz-gly-betahmo25 1874: tolhs-oxadiaz-gly-betahph 1875: phhs-ithiadiaz-gly-zdaptb 1876: bim-42nmeim-bala-betahmofu 1877: 2py-thiadiaz-gly-zdap 1878: bhs-ithiadiaz-gly-betahmo
30 1879: bim-25thiaz-gly-aspibua 1880: bhs-nme35pyr-gly-betapy 1881: bhs-ithiadiaz-ala-betapy 1882: ibhs-nme35pyr-bala-betafphe 1883: bhs-53pyrazo-bala-betadcph30 1879: bim-25thiaz-gly-aspibua 1880: bhs-nme35pyr-gly-betapy 1881: bhs-ithiadiaz-ala-betapy 1882: ibhs-nme35pyr-bala-betafphe 1883: bhs-53pyrazo-bala-betadcph
35 1884 : ibhs-25methiaz-gly-betahcbph 1885 : tolhs-25methiaz-gly-betaphethio 1886: bhs-24thiaz-bala-beta23meoph 1887: ibhs-nme35pyr-gly-zdap 1888: bhs-25thiaz-gly-betadcphtb 1889: gua-26py-gly-betacbph35 1884: ibhs-25methiaz-gly-betahcbph 1885: tolhs-25methiaz-gly-betaphethio 1886: bhs-24thiaz-bala-beta23meoph 1887: ibhs-nme35pyr-gly-zdap 1888: bhs-25thiaz-gly-betadcphtb 1889: gua- 26py-gly-betacbph
40 1890: 2py-25thiaz-gly-betathio3 1891 : tolhs-24thioph-bala-betapyee 1892 : bhs-oxadiaz-gly-betaoxaz 1893: ibhs-25thiaz-bala-betahdbph 1894 : ibhs-ithiadiaz-bala-betaheph40 1890: 2py-25thiaz-gly-betathio3 1891: tolhs-24thioph-bala-betapyee 1892: bhs-oxadiaz-gly-betaoxaz 1893: ibhs-25thiaz-bala-betahdbph 1894: ibhs-ithiadiaz-bala-betaheph
45 1895: ibhs-24thiaz-gly-betahmofu 1896 : tolhs-24thioph-bala-betaoxaz 1897 : phhs-25methiaz-gly-betapbiph 1898: tolhs-24thiaz-gly-betamethi45 1895: ibhs-24thiaz-gly-betahmofu 1896: tolhs-24thioph-bala-betaoxaz 1897: phhs-25methiaz-gly-betapbiph 1898: tolhs-24thiaz-gly-betamethi
1899: tolhs-24thiaz-bala-betamethioph1899: tolhs-24thiaz-bala-betamethioph
1900 : bhs-ithiadiaz-bala-betapyee1900: bras-ithiadiaz-bala-betapyee
1901: bhs-25thiaz-bala-zdaptb 5 1902: ibhs-nme35pyr-bala-beta34meoph1901: bhs-25thiaz-bala-zdaptb 5 1902: ibhs-nme35pyr-bala-beta34meoph
1903: tolhs-me25thioph-ala-zdap1903: tolhs-me25thioph-ala-zdap
1904 : ibhs-25methiaz-gly-betaamibe1904: ibhs-25methiaz-gly-betaamibe
1905: phhs-25oxaz-bala-betabdimo1905: phhs-25oxaz-bala-betabdimo
1906: 2py-triaz-gly-betapy1906: 2py-triaz-gly-betapy
1907 : ibhs-25oxaz-bala-betadcphch1907: ibhs-25oxaz-bala-betadcphch
10 1908: bhs-oxadiaz-nmgly-betadmph10 1908: bhs-oxadiaz-nmgly-betadmph
1909: bhs-24thiaz-bala-beta35dbph1909: bhs-24thiaz-bala-beta35dbph
1910: tolhs-24thioph-gly-betapy1910: tolhs-24thioph-gly-betapy
1911: gua-26py-gly-betacthioph1911: gua-26py-gly-betacthioph
1912: bhs-25oxaz-bala-betapy 15 1913: dhpyrr-25thiaz-gly-betapy1912: bhs-25oxaz-bala-betapy 15 1913: dhpyrr-25thiaz-gly-betapy
1914: tolhs-24thioph-bala-betapym1914: tolhs-24thioph-bala-betapym
1915: ibhs-24thioph-bala-betapbiph1915: ibhs-24thioph-bala-betapbiph
1916: gua-26py-gly-betaipro1916: gua-26py-gly-betaipro
1917: bim-oxadiaz-bala-aspibua 20 1918: tolhs-nme35pyr-bala-betadtrif1917: bim-oxadiaz-bala-aspibua 20 1918: tolhs-nme35pyr-bala-betadtrif
1919: tolhs-25thiaz-gly-betafluo1919: tolhs-25thiaz-gly-betafluo
1920: phhs-oxadiaz-bala-beta23meoph1920: phhs-oxadiaz-bala-beta23meoph
1921: tolhs-25oxaz-bala-beta34dcph1921: tolhs-25oxaz-bala-beta34dcph
1922: 2py-me24oxaz-ala-betapy1922: 2py-me24oxaz-ala-betapy
1923: tolhs-25methiaz-gly-betapym1923: tolhs-25methiaz-gly-betapym
25 1924: phhs-nme35pyr-gly-betahdcph25 1924: phhs-nme35pyr-gly-betahdcph
1925: tolhs-oxadiaz-gly-betafbph1925: tolhs-oxadiaz-gly-betafbph
1926: tolhs-25methiaz-bala-csdap1926: tolhs-25methiaz-bala-csdap
1927: bhs-24im-gly-psdap1927: bhs-24im-gly-psdap
1928 : 2py-me25oxaz-bala-beta34meoph 30 1929: ibhs-25oxaz-gly-betahdbph1928: 2py-me25oxaz-bala-beta34meoph 30 1929: ibhs-25oxaz-gly-betahdbph
1930 : ibhs-oxadiaz-bala-betahcbph1930: ibhs-oxadiaz-bala-betahcbph
1931: phhs-24thioph-bala-csdap1931: phhs-24thioph-bala-csdap
1932 : tolhs-24thiaz-gly-betameph1932: tolhs-24thiaz-gly-betameph
1933: bhs-24thioph-gly-betacbph 35 1934: ibhs-24thiaz-gly-psdapee1933: bhs-24thioph-gly-betacbph 35 1934: ibhs-24thiaz-gly-psdapee
1935: phhs-24thiaz-gly-betafluo1935: phhs-24thiaz-gly-betafluo
1936: gua-42pym-gly-betacthioph1936: gua-42pym-gly-betacthioph
1937: bhs-25thiaz-bala-betadhbfu1937: bhs-25thiaz-bala-betadhbfu
1938: bhs-oxadiaz-bala-betadhbfu1938: bras-oxadiaz-bala-betadhbfu
1939: phhs-25methiaz-gly-busu2be1939: phhs-25methiaz-gly-busu2be
40 1940: phhs-24thiaz-gly-psdap40 1940: phhs-24thiaz-gly-psdap
1941 : ibhs-24thioph-bala-betathiobe1941: ibhs-24thioph-bala-betathiobe
1942 : phhs-ithiadiaz-gly-betatbuph1942: phhs-ithiadiaz-gly-betatbuph
1943 : tolhs-25methiaz-bala-betahmofu1943: tolhs-25methiaz-bala-betahmofu
1944: sabhs-24thioph-gly-psdap 45 1945: ibhs-25oxaz-gly-betaoxope1944: sabhs-24thioph-gly-psdap 45 1945: ibhs-25oxaz-gly-betaoxope
1946: tolhs-25thiaz-gly-beta34dcph1946: Tolhs-25thiaz-gly-beta34dcph
1947: phhs-nme35pyr-gly-betabph 1948: phhs-25thiaz-gly-betatrif1947: phhs-nme35pyr-gly-betabph 1948: phhs-25thiaz-gly-betatrif
1949: bhs-ithiadiaz-ala-betadito1949: bhs-ithiadiaz-ala-betadito
1950: bim-25thiaz-ala-betameph1950: bim-25thiaz-ala-betameph
1951: 2py-35fur-gly-betadcph 5 1952: ibhs-25methiaz-gly-betabdimo1951: 2py-35fur-gly-betadcph 5 1952: ibhs-25methiaz-gly-betabdimo
1953: cima-24thioph-bala-psdap1953: cima-24thioph-bala-psdap
1954: phhs-24thioph-gly-betafph1954: phhs-24thioph-gly-betafph
1955 : ibhs-ithiadiaz-bala-betafphe1955: ibhs-ithiadiaz-bala-betafphe
1956: bim-24im-leu-betapy1956: bim-24im-leu-betapy
1957: bhs-25thioph-gly-betacph1957: bhs-25thioph-gly-betacph
10 1958: impy-24thiaz-bala-betainyl10 1958: impy-24thiaz-bala-betainyl
1959: bim-25methiaz-bala-asppha1959: bim-25methiaz-bala-asppha
1960 : bhs-24thioph-bala-betadcphtb1960: bhs-24thioph-bala-betadcphtb
1961: ibhs-oxadiaz-bala-psdaptb1961: ibhs-oxadiaz-bala-psdaptb
1962: 2py-me24thioph-gly-psdap 15 1963: 2pmhs-24thiaz-bala-betamethioph1962: 2py-me24thioph-gly-psdap 15 1963: 2 pmhs-24thiaz-bala-betamethioph
1964: ibhs-25methiaz-bala-betampy1964: ibhs-25methiaz-bala-betampy
1965: bhs-24thiophme-gly-betameph1965: bhs-24thiophme-gly-betameph
1966: bhs-ithiadiaz-gly-betatrif1966: bras-ithiadiaz-gly-betatrif
1967: dhim-26py-ala-betatbuph 20 1968: thpym-25thiaz-gly-betadcph1967: dhim-26py-ala-betatbuph 20 1968: thpym-25thiaz-gly-betadcph
1969: 2py-thiadiaz-ala-betapy1969: 2py-thiadiaz-ala-betapy
1970: 2py-25methiaz-bala-betaoxope1970: 2py-25methiaz-bala-betaoxope
1971: tolhs-25methiaz-gly-ibsdap1971: tolhs-25methiaz-gly-ibsdap
1972 : ibhs-ithiadiaz-gly-betaoxaz1972: ibhs-ithiadiaz-gly-betaoxaz
1973: phhs-25thiaz-bala-asppha1973: phhs-25thiaz-bala-asppha
25 1974: 2py-42nmeim-gly-betampy25 1974: 2py-42nmeim-gly-betampy
1975: 2py-26py-ala-betapy1975: 2py-26py-ala-betapy
1976: phhs-24thiaz-gly-betadcphtb1976: phhs-24thiaz-gly-betadcphtb
1977: 3pmhs-24thioph-bala-betapy1977: 3 pmhs-24thioph-bala-betapy
1978: 2py-25thiaz-bala-aspbzla 30 1979: gua-42pym-gly-betahmo1978: 2py-25thiaz-bala-aspbzla 30 1979: gua-42pym-gly-betahmo
1980: gua-26py-gly-betaamibe1980: gua-26py-gly-betaamibe
1981: tolhs-25methiaz-gly-zdapee1981: tolhs-25methiaz-gly-zdapee
1982: ibhs-25oxaz-gly-psdapch1982: ibhs-25oxaz-gly-psdapch
1983: bhs-25thiaz-nmgly-betadmph 35 1984: bhs-nme35pyr-bala-betadmoph1983: bhs-25thiaz-nmgly-betadmph 35 1984: bhs-nme35pyr-bala-betadmoph
1985: agua-25thiaz-gly-betadcph1985: agua-25thiaz-gly-betadcph
1986: phhs-25methiaz-gly-betameph1986: phhs-25methiaz-gly-betameph
1987: bhs-24thiaz-gly-beta35dbph1987: bhs-24thiaz-gly-beta35dbph
1988 : ibhs-ithiadiaz-gly-betafphe1988: ibhs-ithiadiaz-gly-betafphe
1989: bim-25oxaz-leu-betapy1989: bim-25oxaz-leu-betapy
40 1990: phhs-ithiadiaz-bala-betahmph40 1990: phhs-ithiadiaz-bala-betahmph
1991: 2py-24thioph-bala-betaet1991: 2py-24thioph-bala-betet
1992: 2py-me2 thiaz-gly-betaph1992: 2py-me2 thiaz-gly-betaph
1993: 2py-24im-ala-betadcph1993: 2py-24im-ala-betadcph
1994: bhs-25thiaz-gly-betadmoph 45 1995: phhs-ithiadiaz-bala-betaet1994: bhs-25thiaz-gly-betadmoph 45 1995: phhs-ithiadiaz-bala-betaet
1996 : ibhs-25 hiaz-bala-betaphethio1996: ibhs-25 hiaz-bala-betaphethio
1997: phhs-oxadiaz-bala-betahbcph 1998: ibhs-25methiaz-bala-betafphe 1999: ibhs-25thiaz-gly-suabu 2000: bim-24thiaz-ala-betameph 2001: phhs-me25thiaz-bala-betaph 5 2002: ibhs-25thiaz-gly-betapyr 2003: bhs-me25thioph-bala-betaph1997: phhs-oxadiaz-bala-betahbcph 1998: ibhs-25methiaz-bala-betafphe 1999: ibhs-25thiaz-gly-suabu 2000: bim-24thiaz-ala-betameph 2001: phhs-me25thiaz-bala-betaph 5 2002: ibhs-25thiaz-gly-betapyr 2003: bhs- me25thioph-bala-betaph
2004: bhs-25oxaz-bala-aspaba2004: bras-25oxaz-bala-aspaba
2005: 2pmhs-25thiaz-bala-betathioph2005: 2 pmhs-25thiaz-bala-betathioph
2006: tolhs-oxadiaz-bala-psdap2006: tolhs-oxadiaz-bala-psdap
2007: bhs-nme35pyr-gly-betaoxaz2007: bhs-nme35pyr-gly-betaoxaz
1010
2008: tolhs-25thiaz-gly-beta23meoph2008: tolhs-25thiaz-gly-beta23meoph
2009: phhs-25methiaz-gly-betaamibe2009: phhs-25methiaz-gly-betaamibe
2010: gua-25thioph-gly-betapy2010: gua-25thioph-gly-betapy
2011: 2py-nme35pyr-gly-psdap2011: 2py-nme35pyr-gly-psdap
2012 : ibhs-ithiadiaz-gly-betahdbph 15 2013: 2py-25oxaz-gly-betacbph2012: ibhs-ithiadiaz-gly-betahdbph 15 2013: 2py-25oxaz-gly-betacbph
2014: bim-me24thioph-leu-zdap2014: bim-me24thioph-leu-zdap
2015 : bhs-25thiaz-ala-betal3bendi2015: bhs-25thiaz-ala-betal3bendi
2016: phhs-24thioph-gly-betatrif2016: phhs-24thioph-gly-betatrif
2017: 2py-ithiadiaz-gly-betapy 20 2018: phhs-nme35pyr-gly-betapytb2017: 2py-ithiadiaz-gly-betapy 20 2018: phhs-nme35pyr-gly-betapytb
2019: ibhs-ithiadiaz-gly-betaanaphth2019: ibhs-ithiadiaz-gly-betaanaphth
2020: bhs-nme35pyr-ala-betaanaphth2020: bhs-nme35pyr-ala-betaanaphth
2021: tolhs-nme35pyr-gly-betapych2021: tolhs-nme35pyr-gly-betapych
2022: 2py-me25thioph-bala-psdap2022: 2py-me25thioph-bala-psdap
2023: ibhs-24thiaz-gly-betaet2023: ibhs-24thiaz-gly-betaet
25 2024 : tolhs-24thioph-gly-beta3quin25 2024: tolhs-24thioph-gly-beta3quin
2025: tolhs-24thiaz-bala-betaoxope2025: tolhs-24thiaz-bala-betaoxope
2026 : ibhs-25methiaz-gly-beta34meoph2026: ibhs-25methiaz-gly-beta34meoph
2027: ibhs-25oxaz-bala-betambiph2027: ibhs-25oxaz-bala-betambiph
2028: phhs-25oxaz-gly-betafbph 30 2029: tolhs-24thiaz-gly-betathio32028: phhs-25oxaz-gly-betafbph 30 2029: tolhs-24thiaz-gly-betathio3
2030 : phhs-ithiadiaz-gly-betaipro2030: phhs-ithiadiaz-gly-betaipro
2031 : phhs-25oxaz-gly-betacthioph2031: phhs-25oxaz-gly-betacthioph
2032: bhs-25thiaz-bala-betaibph2032: bhs-25thiaz-bala-betaibph
2033: impy-24thioph-nmgly-psdap 35 2034: bhs-24im-gly-zdap2033: impy-24thioph-nmgly-psdap 35 2034: bhs-24im-gly-zdap
2035: bhs-thiadiaz-leu-betapy2035: bhs-thiadiaz-leu-betapy
2036: gua-25thiophme-gly-betapy2036: gua-25thiophme-gly-betapy
2037: bhs-24thiaz-gly-betafluo2037: bhs-24thiaz-gly-betafluo
2038: tolhs-oxadiaz-bala-betathioph2038: tolhs-oxadiaz-bala-betathioph
2039: bhs-24im-ala-betapy2039: bhs-24im-ala-betapy
40 2040: bhs-24thiaz-bala-betabph40 2040: bras-24thiaz-bala-betabph
2041: bim-25oxaz-bala-betathioph2041: bim-25oxaz-bala-betathioph
2042: bhs-nme35pyr-gly-betaaird.be2042: bhs-nme35pyr-gly-betaaird.be
2043 : phhs-25oxaz-gly-beta23meoph2043: phhs-25oxaz-gly-beta23meoph
2044 : ibhs-ithiadiaz-gly-betabdimo 45 2045: phhs-25methiaz-gly-betaipro2044: ibhs-ithiadiaz-gly-betabdimo 45 2045: phhs-25methiaz-gly-betaipro
2046 : phhs-24thiaz-gly-beta34meoph2046: phhs-24thiaz-gly-beta34meoph
2047: phhs-25thiaz-gly-betafluo 2048: bhs-25methiaz-bala-betaanaphth2047: phhs-25thiaz-gly-betafluo 2048: bhs-25methiaz-bala-betaanaphth
2049: tolhs-25thiaz-bala-psdapee2049: tolhs-25thiaz-bala-psdapee
2050: tolhs-24thiaz-gly-betafphe2050: tolhs-24thiaz-gly-betafphe
2051: bhs-24thioph-gly-betafluo 5 2052: phhs-nme35pyr-gly-betahni2051: bhs-24thioph-gly-betafluo 5 2052: phhs-nme35pyr-gly-betahni
2053: 2py-me24thioph-bala-betapy2053: 2py-me24thioph-bala-betapy
2054: ibhs-25methiaz-gly-betafbph2054: ibhs-25methiaz-gly-betafbph
2055: 2py-nme35pyr-bala-aspaba2055: 2py-nme35pyr-bala-aspaba
2056: bhs-24thiaz-gly-betatbuph2056: bhs-24thiaz-gly-betatbuph
2057: 2py-42pym-gly-betapy2057: 2py-42pym-gly-betapy
2058: tolhs-24thiaz-bala-betahmofu2058: tolhs-24thiaz-bala-betahmofu
2059: ibhs-25thiaz-gly-betatos2059: ibhs-25thiaz-gly-betatos
2060: ibhs-nme35pyr-bala-suabu2060: ibhs-nme35pyr-bala-suabu
2061: ibhs-25methiaz-gly-betarnethioph2061: ibhs-25methiaz-gly-betarnethioph
2062: ibhs-25thiaz-bala-betadito 15 2063: hyd-24thiaz-bala-betameph2062: ibhs-25thiaz-bala-betadito 15 2063: hyd-24thiaz-bala-betameph
2064: tolhs-nme35pyr-gly-betacph2064: tolhs-nme35pyr-gly-betacph
2065: bhs-25oxaz-ala-betafphe2065: bras-25oxaz-ala-betafphe
2066: bhs-oxadiaz-gly-aspbzla2066: bhs-oxadiaz-gly-aspbzla
2067: tolhs-24thiaz-bala-ibsdap 20 2068: bim-ithiadiaz-leu-betadcph2067: tolhs-24thiaz-bala-ibsdap 20 2068: bim-ithiadiaz-leu-betadcph
2069: 2py-24thioph-gly-betaol2069: 2py-24thioph-gly-betaol
2070: tolhs-24thiaz-gly-betamesu2070: tolhs-24thiaz-gly-betamesu
2071: ibhs-24thiaz-gly-betahdcph2071: ibhs-24thiaz-gly-betahdcph
2072 : bhs-25methiaz-nmgly-beta3quin2072: bhs-25methiaz-nmgly-beta3quin
2073 : ibhs-24thioph-gly-betaphethio2073: ibhs-24thioph-gly-betaphethio
2074: bhs-24thioph-bala-betathiobe2074: bras-24thioph-bala-betathiobe
2075: bhs-25thiaz-gly-asppha2075: bhs-25thiaz-gly-asppha
2076 : phhs-nme35pyr-bala-betaphethioa2076: phhs-nme35pyr-bala-betaphethioa
2077: 2py-25methiaz-leu-betadcph2077: 2py-25methiaz-leu-betadcph
2078: tolhs-ithiadiaz-bala-betafphe 30 2079: bhs-25oxaz-bala-betadmph2078: tolhs-ithiadiaz-bala-betafphe 30 2079: bhs-25oxaz-bala-betadmph
2080: bhs-nme35pyr-bala-betaftrif2080: bras-nme35pyr-bala-betaftrif
2081: tolhs-25methiaz-gly-betapyee2081: tolhs-25methiaz-gly-betapyee
2082: bim-oxadiaz-leu-psdap2082: bim-oxadiaz-leu-psdap
2083: tolhs-ithiadiaz-gly-betahc 35 2084: gua-25thiaz-gly-betahc2083: tolhs-ithiadiaz-gly-betahc 35 2084: gua-25thiaz-gly-betahc
2085: 2py-53pyrazo-gly-zdap2085: 2py-53pyrazo-gly-zdap
2086: nmhs-42pym-gly-betainyl2086: nmhs-42pym-gly-betainyl
2087: tolhs-24thiaz-gly-betainyl2087: tolhs-24thiaz-gly-betainyl
2088: phhs-25oxaz-bala-psdapch2088: phhs-25oxaz-bala-psdapch
2089: bhs-24thiaz-gly-betathiome 40 2090: bhs-nme35pyr-gly-betabedιox2089: bhs-24thiaz-gly-betathiome 40 2090: bhs-nme35pyr-gly-betabedιox
2091: phhs-25thiaz-gly-betahph2091: phhs-25thiaz-gly-betahph
2092: bhs-24thiaz-nmgly-betabpy2092: bhs-24thiaz-nmgly-betabpy
2093: ibhs-25methiaz-bala-be afu32093: ibhs-25methiaz-bala-be afu3
2094 : phhs-24thioph-gly-betaoxope2094: phhs-24thioph-gly-betaoxope
45 2095: bhs-25methiaz-gly-busu2be45 2095: bhs-25methiaz-gly-busu2be
2096: dhim-24thiaz-ala-zdap2096: dhim-24thiaz-ala-zdap
2097 : bhs-ithiadiaz-bala-betainyl 2098: phhs-25methiaz-gly-betaomebendi 2099: bim-52thiaz-ala-betameph 2100: bim-35thioph-bala-zdap 2101: ibhs-25thiaz-bala-aspbzla 5 2102: ibhs-25thiaz-gly-busu2be2097: bhs-ithiadiaz-bala-betainyl 2098: phhs-25methiaz-gly-betaomebendi 2099: bim-52thiaz-ala-betameph 2100: bim-35thioph-bala-zdap 2101: ibhs-25thiaz-bala-aspbzla 5 2102: ibhs-25thiaz-gly-busu2be
2103 : tolhs-nme35pyr-gly-betaomebendi2103: tolhs-nme35pyr-gly-betaomebendi
2104: phhs-25methiaz-gly-betaet2104: phhs-25methiaz-gly-betaet
2105: bhs-24thiaz-gly-betahdcph2105: bhs-24thiaz-gly-betahdcph
2106: bim-42nmeim-gly-betah35dc2106: bim-42nmeim-gly-betah35dc
2107: bhs-me24thioph-gly-betapy2107: bhs-me24thioph-gly-betapy
10 2108: phhs-25thiaz-gly-zdapee10 2108: phhs-25thiaz-gly-zdapee
2109: ibhs-nme35pyr-bala-betadbph2109: ibhs-nme35pyr-bala-betadbph
2110: tolhs-me25thiaz-gly-betaph2110: tolhs-me25thiaz-gly-betaph
2111: bhs-me25thioph-bala-zdap2111: bhs-me25thioph-bala-zdap
2112: impy-25oxaz-bala-betadmoph 15 2113: tolhs-25thiaz-bala-betal3bendi2112: impy-25oxaz-bala-betadmoph 15 2113: tolhs-25thiaz-bala-betal3bendi
2114: bhs-35fur-gly-psdap2114: bhs-35fur-gly-psdap
2115: gua-25thioph-gly-betaph2115: gua-25thioph-gly-betaph
2116: ibhs-25oxaz-bala-betaamibe2116: ibhs-25oxaz-bala-betaamibe
2117: 2py-24oxaz-leu-betadcph 2o 2118: ibhs-ithiadiaz-gly-betahmofu2117: 2py-24oxaz-leu-betadcph 2o 2118: ibhs-ithiadiaz-gly-betahmofu
2119: bim-25thioph-ala-betapy2119: bim-25thioph-ala-betapy
2120 : ibhs-ithiadiaz-gly-betadcphee2120: ibhs-ithiadiaz-gly-betadcphee
2121: tolhs-me25oxaz-gly-betadcph2121: tolhs-me25oxaz-gly-betadcph
2122 : tolhs-25methiaz-bala-betaheph2122: tolhs-25methiaz-bala-betaheph
2123: ibhs-ithiadiaz-gly-betapy2123: ibhs-ithiadiaz-gly-betapy
2124: bhs-35py-ala-betapy2124: bhs-35py-ala-betapy
2125: bhs-35thioph-bala-psdap2125: bhs-35thioph-bala-psdap
2126: tolhs-me24thioph-bala-zdap2126: tolhs-me24thioph-bala-zdap
2127 : phhs-25methiaz-gly-betahdcph2127: phhs-25methiaz-gly-betahdcph
2128: bhs-25thiaz-bala-psdapee 30 2129: bhs-me25thioph-gly-beta34meoph2128: bhs-25thiaz-bala-psdapee 30 2129: bhs-me25thioph-gly-beta34meoph
2130: phhs-oxadiaz-gly-betahdcph2130: phhs-oxadiaz-gly-betahdcph
2131: tolhs-25oxaz-gly-betaanaphth2131: tolhs-25oxaz-gly-betaanaphth
2132: tolhs-25thiaz-bala-csdap2132: tolhs-25thiaz-bala-csdap
2133: 2py-ithiadiaz-leu-zdap 35 2134: ibhs-25oxaz-bala-betamethi2133: 2py-ithiadiaz-leu-zdap 35 2134: ibhs-25oxaz-bala-betamethi
2135: bhs-25oxaz-bala-aspbzla2135: bras-25oxaz-bala-aspbzla
2136: phhs-nme35pyr-bala-betah35dc2136: phhs-nme35pyr-bala-betah35dc
2137 : ibhs-24 hioph-bala-betadcphch2137: ibhs-24 hioph-bala-betadcphch
2138: phhs-25methiaz-bala-betathiome2138: phhs-25methiaz-bala-betathiome
2139: 2py-52thiaz-ala-betapy2139: 2py-52thiaz-ala-betapy
40 2140: ibhs-24thioph-gly-betabdimo40 2140: ibhs-24thioph-gly-betabdimo
2141 : dimethpym-25thiaz-gly-betameph2141: dimethpym-25thiaz-gly-betameph
2142 : bhs-25methiaz-gly-betaftrif2142: bhs-25methiaz-gly-betaftrif
2143: tolhs-24thiaz-gly-betacph2143: tolhs-24thiaz-gly-betacph
2144: bhs-oxadiaz-bala-betapytb 45 2145: ibhs-oxadiaz-bala-betafbph2144: bhs-oxadiaz-bala-betapytb 45 2145: ibhs-oxadiaz-bala-betafbph
2146: ibhs-25thiaz-gly-betacbph2146: ibhs-25thiaz-gly-betacbph
2147 : phhs-24thioph-bala-betafluo 2148: phhs-me24thiaz-bala-beta34meoph2147: phhs-24thioph-bala-betafluo 2148: phhs-me24thiaz-bala-beta34meoph
2149: tolhs-25thiaz-bala-betapyr2149: tolhs-25thiaz-bala-betapyr
2150: phhs-25oxaz-bala-betadhbfu2150: phhs-25oxaz-bala-betadhbfu
2151: ibhs-25oxaz-bala-betadito 5 2152: bhs-24thioph-gly-betameph2151: ibhs-25oxaz-bala-betadito 5 2152: bhs-24thioph-gly-betameph
2153: bhs-24thioph-bala-betacbph2153: bhs-24thioph-bala-betacbph
2154: bim-25oxaz-gly-aspbzla2154: bim-25oxaz-gly-aspbzla
2155: impy-24thioph-gly-beta34meoph2155: impy-24thioph-gly-beta34meoph
2156 : bhs-ithiadiaz-nmgly-betadmoph2156: bhs-ithiadiaz-nmgly-betadmoph
2157: bim-35thioph-ala-betapy2157: bim-35thioph-ala-betapy
1010
2158: tolhs-25thiaz-bala-betadmph2158: tolhs-25thiaz-bala-betadmph
2159: phhs-24thioph-bala-betaphethioa2159: phhs-24thioph-bala-betaphethioa
2160: ibhs-25oxaz-bala-betafu22160: ibhs-25oxaz-bala-betafu2
2161: ibhs-nme35pyr-gly-betatrif2161: ibhs-nme35pyr-gly-betatrif
2162: 2py-24thiaz-gly-beta3quin 15 2163: 2pmhs-25thiaz-gly-psdap2162: 2py-24thiaz-gly-beta3quin 15 2163: 2 pmhs-25thiaz-gly-psdap
2164: bhs-25oxaz-gly-betatos2164: bhs-25oxaz-gly-betatos
2165 : tolhs-25methiaz-gly-beta3quin2165: tolhs-25methiaz-gly-beta3quin
2166 : tolhs-24thioph-bala-betabthioph2166: tolhs-24thioph-bala-betabthioph
2167 : impy-25methiaz-bala-betamesu 20 2168: phhs-25oxaz-bala-psdapee2167: impy-25methiaz-bala-betamesu 20 2168: phhs-25oxaz-bala-psdapee
2169: tolhs-25thiaz-gly-betah35dc2169: tolhs-25thiaz-gly-betah35dc
2170 : tolhs-24thioph-bala-betafu32170: tolhs-24thioph-bala-betafu3
2171 : bhs-25methiaz-gly-betabdimo2171: bhs-25methiaz-gly-betabdimo
2172: bhs-25fur-gly-betadcph2172: bhs-25fur-gly-betadcph
2173 : phhs-ithiadiaz-bala-psdapch2173: phhs-ithiadiaz-bala-psdapch
2525
2174: tolhs-25oxaz-gly-betadito2174: tolhs-25oxaz-gly-betadito
2175: tolhs-oxadiaz-gly-betamesu2175: tolhs-oxadiaz-gly-betamesu
2176: bhs-25oxaz-bala-betabenfu2176: bras-25oxaz-bala-betabenfu
2177 : ibhs-25methiaz-gly-betadcph2177: ibhs-25methiaz-gly-betadcph
2178: bhs-24thioph-gly-betadito 30 2179: ibhs-24thiaz-bala-betaoxope2178: bhs-24thioph-gly-betadito 30 2179: ibhs-24thiaz-bala-betaoxope
2180: tolhs-25methiaz-bala-betampy2180: tolhs-25methiaz-bala-betampy
2181: ibhs-ithiadiaz-bala-aspaba2181: ibhs-ithiadiaz-bala-aspaba
2182: 2py-me25oxaz-ala-betadcph2182: 2py-me25oxaz-ala-betadcph
2183: ibhs-24thioph-gly-betapytb 35 2184: ibhs-ithiadiaz-bala-betainyl2183: ibhs-24thioph-gly-betapytb 35 2184: ibhs-ithiadiaz-bala-betainyl
2185: phhs-me25thiaz-gly-psdap2185: phhs-me25thiaz-gly-psdap
2186: phhs-oxadiaz-gly-betahb2186: phhs-oxadiaz-gly-betahb
2187: bhs-nme35pyr-ala-beta34dcph2187: bhs-nme35pyr-ala-beta34dcph
2188: phhs-me24thiaz-ala-zdap2188: phhs-me24thiaz-ala-zdap
2189: bhs-42nmeim-leu-betapy2189: bhs-42nmeim-leu-betapy
40 2190 : tolhs-24thiaz-gly-betaf rif40 2190: tolhs-24thiaz-gly-beta rif
2191: ibhs-oxadiaz-gly-betahmph2191: ibhs-oxadiaz-gly-betahmph
2192: tolhs-ithiadiaz-bala-betahb2192: tolhs-ithiadiaz-bala-betahb
2193: bhs-35thioph-leu-betadcph2193: bhs-35thioph-leu-betadcph
2194: bhs-25thiaz-bala-betadcph 45 2195: phhs-nme35pyr-gly-betapyr2194: bhs-25thiaz-bala-betadcph 45 2195: phhs-nme35pyr-gly-betapyr
2196: ibhs-ithiadiaz-gly-zdap2196: ibhs-ithiadiaz-gly-zdap
2197 : phhs-25oxaz-bala-betahdcph 2198: bhs-oxadiaz-gly-betaibph2197: phhs-25oxaz-bala-betahdcph 2198: bhs-oxadiaz-gly-betaibph
2199: 2py-me24thioph-leu-betaph2199: 2py-me24thioph-leu-betaph
2200: tolhs-24thioph-gly-beta34dcph2200: tolhs-24thioph-gly-beta34dcph
2201: bhs-24thiaz-nmgly-betacph 5 2202: bhs-25oxaz-bala-betapyr2201: bhs-24thiaz-nmgly-betacph 5 2202: bhs-25oxaz-bala-betapyr
2203: bhs-25fur-leu-zdap2203: bras-25fur-leu-zdap
2204: impy-24oxaz-gly-betameph2204: impy-24oxaz-gly-betameph
2205: bhs-nme35pyr-gly-betahb2205: bhs-nme35pyr-gly-betahb
2206: tolhs-me24thiaz-bala-psdap2206: tolhs-me24thiaz-bala-psdap
2207 : ibhs-24thioph-gly-beta35dbph2207: ibhs-24thioph-gly-beta35dbph
1010
2208: ibhs-24thioph-bala-betathio32208: ibhs-24thioph-bala-betathio3
2209: bhs-24thiaz-bala-asppha2209: bras-24thiaz-bala-asppha
2210 : bhs-24thioph-ala-betaanaphth2210: bhs-24thioph-ala-betaanaphth
2211: ibhs-24thioph-bala-betahph2211: ibhs-24thioph-bala-betahph
2212: tolhs-nme35pyr-bala-asppha 15 2213: bim-thiadiaz-leu-zdap2212: tolhs-nme35pyr-bala-asppha 15 2213: bim-thiadiaz-leu-zdap
2214: 2py-35fur-bala-betapy2214: 2py-35fur-bala-betapy
2215: phhs-24thioph-bala-betathioph2215: phhs-24thioph-bala-betathioph
2216: phhs-ithiadiaz-bala-betadhbfu2216: phhs-ithiadiaz-bala-betadhbfu
2217: bhs-25thiaz-nmgly-betameph 20 2218: tolhs-ithiadiaz-gly-betahb2217: bhs-25thiaz-nmgly-betameph 20 2218: tolhs-ithiadiaz-gly-betahb
2219: 2py-ithiadiaz-gly-aspibua2219: 2py-ithiadiaz-gly-aspibua
2220 : ibhs-25methiaz-bala-betamethioph2220: ibhs-25methiaz-bala-betamethioph
2221: bhs-oxadiaz-gly-betaet2221: bhs-oxadiaz-gly-betet
2222: ibhs-nme35pyr-gly-betatos2222: ibhs-nme35pyr-gly-betatos
2223: bhs-me25oxaz-gly-psdap2223: bhs-me25oxaz-gly-psdap
25 2224: bhs-25oxaz-bala-zdapee25 2224: bras-25oxaz-bala-zdapee
2225: bhs-26py-gly-betal3bendi2225: bhs-26py-gly-betal3bendi
2226: bhs-25fur-ala-betadcph2226: bras-25fur-ala-betadcph
2227: ibhs-24thioph-gly-zdapch2227: ibhs-24thioph-gly-zdapch
2228: tolhs-25thiaz-bala-betadcphtb 30 2229: phhs-24thioph-bala-betadbph2228: tolhs-25thiaz-bala-betadcphtb 30 2229: phhs-24thioph-bala-betadbph
2230: 2py-25oxaz-bala-aspbzla2230: 2py-25oxaz-bala-aspbzla
2231 : 2py-me25thioph-ala-beta34meoph2231: 2py-me25thioph-ala-beta34meoph
2232 : ibhs-25thiaz-bala-beta34meoph2232: ibhs-25thiaz-bala-beta34meoph
2233: ibhs-24thioph-bala-zdap 35 2234: phhs-24thiaz-bala-betathio32233: ibhs-24thioph-bala-zdap 35 2234: phhs-24thiaz-bala-betathio3
2235: bhs-24thioph-bala-betatrif2235: bras-24thioph-bala-betatrif
2236: bhs-nme35pyr-bala-betadito2236: bhs-nme35pyr-bala-betadito
2237: phhs-nme35pyr-gly-betacbph2237: phhs-nme35pyr-gly-betacbph
2238: bhs-24thioph-ala-betaoxaz2238: bhs-24thioph-ala-betaoxaz
2239 : impy-25thiaz-bala-betaphethioa2239: impy-25thiaz-bala-betaphethioa
40 2240: 2py-25oxaz-bala-betafu340 2240: 2py-25oxaz-bala-betafu3
2241: 2py-oxadiaz-ala-betapy2241: 2py-oxadiaz-ala-betapy
2242: ibhs-25methiaz-bala-betaet2242: ibhs-25methiaz-bala-betet
2243 : ibhs-ithiadiaz-gly-betatbuph2243: ibhs-ithiadiaz-gly-betatbuph
2244: phhs-24thioph-bala-betaol 45 2245: phhs-25thiaz-bala-beta23meoph2244: phhs-24thioph-bala-betaol 45 2245: phhs-25thiaz-bala-beta23meoph
2246 : phhs-25oxaz-bala-betabthioph2246: phhs-25oxaz-bala-betabthioph
2247: bim-24im-bala-psdap 2248: bim-nme35pyr-gly-aspaba2247: bim-24im-bala-psdap 2248: bim-nme35pyr-gly-aspaba
2249: ibhs-25oxaz-bala-betaimid2249: ibhs-25oxaz-bala-betaimid
2250: impy-24thiaz-gly-betaipr2250: impy-24thiaz-gly-betaipr
2251: tolhs-25thiaz-bala-betapbiph2251: tolhs-25thiaz-bala-betapbiph
5 2252: phhs- 5oxaz-bala-betadcph5 2252: phhs- 5oxaz-bala-betadcph
2253 : ibhs-ithiadiaz-gly-beta4bph2253: ibhs-ithiadiaz-gly-beta4bph
2254: bhs-oxadiaz-gly-betah.35dc2254: bhs-oxadiaz-gly-betah.35dc
2255: phhs-oxadiaz-gly-betaipro2255: phhs-oxadiaz-gly-betaipro
2256 : bhs-25methiaz-nmgly-betathio32256: bhs-25methiaz-nmgly-betathio3
2257 : bim-35thioph-leu-zdap 10 2258: phhs-25oxaz-bala-betaιpr2257: bim-35thioph-leu-zdap 10 2258: phhs-25oxaz-bala-betaιpr
2259: ibhs-25methiaz-gly-zdapch2259: ibhs-25methiaz-gly-zdapch
2260: bim-me25thiaz-bala-zdap2260: bim-me25thiaz-bala-zdap
2261: phhs-nme35pyr-bala-betaamibe2261: phhs-nme35pyr-bala-betaamibe
2262: bhs-25thiaz-bala-aspaba 15 2263: bhs-24thiaz-gly-betathioph2262: bhs-25thiaz-bala-aspaba 15 2263: bhs-24thiaz-gly-betathioph
2264: bhs-25oxaz-gly-betaphethio2264: bhs-25oxaz-gly-betaphethio
2265 : bhs-ithiadiaz-bala-betabediox2265: bhs-ithiadiaz-bala-betabediox
2266: phhs-nme35pyr-gly-betabnaphth2266: phhs-nme35pyr-gly-betabnaphth
2267: bhs-nme35pyr-gly-betadtrif 20 2268: tolhs-25thiaz-bala-betainyl2267: bhs-nme35pyr-gly-betadtrif 20 2268: tolhs-25thiaz-bala-betainyl
2269 : bhs-24thioph-gly-betabnaphth2269: bhs-24thioph-gly-betabnaphth
2270 : phhs-ithiadiaz-bala-betacbph2270: phhs-ithiadiaz-bala-betacbph
2271 : bhs-25methiaz-bala-betatbuph2271: bhs-25methiaz-bala-betatbuph
2272 : bhs-25methiaz-ala-betathio32272: bhs-25methiaz-ala-betathio3
2273: bim-25methiaz-gly-zdap2273: bim-25methiaz-gly-zdap
2274: tolhs-oxadiaz-gly-betafu22274: tolhs-oxadiaz-gly-betafu2
2275: ibhs-24thiaz-bala-beta35dbph2275: ibhs-24thiaz-bala-beta35dbph
2276: bhs-nme35pyr-gly-betadito2276: bhs-nme35pyr-gly-betadito
2277: bhs-oxadiaz-ala-ibsdap2277: bhs-oxadiaz-ala-ibsdap
2278: ibhs-25methiaz-gly-betal3bendi 30 2279: phhs-24thioph-bala-psdap2278: ibhs-25methiaz-gly-betal3bendi 30 2279: phhs-24thioph-bala-psdap
2280 : ibhs-ithiadiaz-bala-betatos2280: ibhs-ithiadiaz-bala-betatos
2281: tolhs-25thiaz-gly-psdapch2281: tolhs-25thiaz-gly-psdapch
2282: bhs-25methiaz-gly-betadhbfu2282: bhs-25methiaz-gly-betadhbfu
2283: phhs-24thiaz-gly-betaipro 35 2284: ibhs-oxadiaz-gly-zdap2283: phhs-24thiaz-gly-betaipro 35 2284: ibhs-oxadiaz-gly-zdap
2285: tolhs-nme35pyr-bala-betafphe2285: tolhs-nme35pyr-bala-betafphe
2286: bhs-25thiaz-ala-betaoxaz2286: bhs-25thiaz-ala-betaoxaz
2287: ibhs-24thioph-bala-betaet2287: ibhs-24thioph-bala-betet
2288: ibhs-24thiaz-bala-betafu32288: ibhs-24thiaz-bala-betafu3
2289: bhs-25oxaz-ala-ibsdap2289: bhs-25oxaz-ala-ibsdap
40 2290: bhs-25methiaz-nmgly-betadito40 2290: bhs-25methiaz-nmgly-betadito
2291: bim-24thioph-gly-betapbiph2291: bim-24thioph-gly-betapbiph
2292 : ibhs-25thiaz-bala-betadtrif2292: ibhs-25thiaz-bala-betadtrif
2293 : tolhs-25methiaz-bala-betah35dc2293: tolhs-25methiaz-bala-betah35dc
2294 : phhs-25methiaz-gly-betabdimo 45 2295: 2py-25oxaz-bala-aspibua2294: phhs-25methiaz-gly-betabdimo 45 2295: 2py-25oxaz-bala-aspibua
2296: ibhs-25thiaz-bala-betahmofu2296: ibhs-25thiaz-bala-betahmofu
2297 : phhs-oxadiaz-gly-betathiome 2298 : tolhs-oxadiaz-gly-betaomebendi 2299: tolhs-25thiaz-gly-betabmph 2300 : ibhs-oxadiaz-bala-betahdcph2297: phhs-oxadiaz-gly-betathioma 2298: tolhs-oxadiaz-gly-betaomebendi 2299: tolhs-25thiaz-gly-betabmph 2300: ibhs-oxadiaz-bala-betahdcph
2301 : 2py-me24thioph-leu-beta34meoph 5 2302: phhs-nme35pyr-gly-betabediox2301: 2py-me24thioph-leu-beta34meoph 5 2302: phhs-nme35pyr-gly-betabediox
2303: ibhs-nme35pyr-bala-betaibph2303: ibhs-nme35pyr-bala-betaibph
2304 : 2py-me25thioph-bala-beta34meoph2304: 2py-me25thioph-bala-beta34meoph
2305: bhs-24thiaz-bala-betatos2305: bras-24thiaz-bala-betatos
2306: bhs-25thiaz-gly-betaol2306: bhs-25thiaz-gly-betaol
2307: phhs-25oxaz-gly-betahb2307: phhs-25oxaz-gly-betahb
10 2308: ibhs-oxadiaz-bala-betaphethioa10 2308: ibhs-oxadiaz-bala-betaphethioa
2309: tolhs-25thiaz-bala-betahmofu2309: tolhs-25thiaz-bala-betahmofu
2310: bhs-nme35pyr-ala-betahph2310: bhs-nme35pyr-ala-betahph
2311: ibhs-25oxaz-bala-betaibph2311: ibhs-25oxaz-bala-betaibph
2312: tolhs-25oxaz-bala-betadmph 15 2313: 2py-me25oxaz-bala-zdap2312: tolhs-25oxaz-bala-betadmph 15 2313: 2py-me25oxaz-bala-zdap
2314: bhs-24thiaz-gly-betacph2314: bhs-24thiaz-gly-betacph
2315: bim-oxadiaz-ala-zdap2315: bim-oxadiaz-ala-zdap
2316: tolhs-25oxaz-bala-betamethi2316: tolhs-25oxaz-bala-betamethi
2317: 2py-25thioph-ala-betadcph 2o 2318: bhs-24thiaz-nmgly-ibsdap2317: 2py-25thioph-ala-betadcph 2o 2318: bhs-24thiaz-nmgly-ibsdap
2319: bim-42nmeim-gly-busu2be2319: bim-42nmeim-gly-busu2be
2320: phhs-me24thioph-ala-betadcph2320: phhs-me24thioph-ala-betadcph
2321: bhs-24thiaz-nmgly-betadhbfu2321: bhs-24thiaz-nmgly-betadhbfu
2322: 2py-me25thiaz-bala-betapy2322: 2py-me25thiaz-bala-betapy
2323: bim-25thioph-gly-zdap2323: bim-25thioph-gly-zdap
25 2324: tolhs-25oxaz-gly-betahmofu25 2324: tolhs-25oxaz-gly-betahmofu
2325: bhs-25methiaz-gly-betahmofu2325: bhs-25methiaz-gly-betahmofu
2326: phhs-ithiadiaz-bala-suabu2326: phhs-ithiadiaz-bala-suabu
2327: ibhs-25oxaz-gly-betamethi2327: ibhs-25oxaz-gly-betamethi
2328: gua-26py-gly-betapy 30 2329: tolhs-25oxaz-gly-betapy2328: gua-26py-gly-betapy 30 2329: tolhs-25oxaz-gly-betapy
2330: bhs-me25oxaz-ala-betaph2330: bhs-me25oxaz-ala-betaph
2331: tolhs-nme35pyr-gly-betambiph2331: tolhs-nme35pyr-gly-betambiph
2332 : bhs-24thioph-gly-betathiome2332: bhs-24thioph-gly-betathioma
2333: phhs-25thiaz-gly-betaet 35 2334: tolhs-ithiadiaz-bala-betapyr2333: phhs-25thiaz-gly-betaet 35 2334: tolhs-ithiadiaz-bala-betapyr
2335: phhs-24thioph-bala-zdapch2335: phhs-24thioph-bala-zdapch
2336: tolhs-25methiaz-gly-zdap2336: tolhs-25methiaz-gly-zdap
2337: ibhs-24thiaz-gly-betacbph2337: ibhs-24thiaz-gly-betacbph
2338: bhs-oxadiaz-bala-bet hph2338: bhs-oxadiaz-bala-bet hph
2339: tolhs-24thiaz-bala-betafu22339: tolhs-24thiaz-bala-betafu2
40 2340: ibhs-24thiaz-gly-psdap40 2340: ibhs-24thiaz-gly-psdap
2341 : ibhs-ithiadiaz-bala-betabenfu2341: ibhs-ithiadiaz-bala-betabenfu
2342: bim-25oxaz-bala-psdap2342: bim-25oxaz-bala-psdap
2343: phhs-me25oxaz-leu-betapy2343: phhs-me25oxaz-leu-betapy
2344: ibhs-nme35pyr-bala-betabph 45 2345: bim-me25thioph-leu-betadcph2344: ibhs-nme35pyr-bala-betabph 45 2345: bim-me25thioph-leu-betadcph
2346 : bhs-ithiadiaz-bala-betabenfu2346: bhs-ithiadiaz-bala-betabenfu
2347 : phhs-25methiaz-bala-betabthioph 2348: bhs-nme35pyr-bala-psdapee2347: phhs-25methiaz-bala-betabthioph 2348: bhs-nme35pyr-bala-psdapee
2349 : ibhs-24thioph-bala-betabdimo2349: ibhs-24thioph-bala-betabdimo
2350 : ibhs-24thioph-gly-betaoxope2350: ibhs-24thioph-gly-betaoxope
2351: bim-42pym-ala-zdap 5 2352: gua-26py-gly-suabu2351: bim-42pym-ala-zdap 5 2352: gua-26py-gly-suabu
2353: ibhs-25thiaz-bala-betaipro2353: ibhs-25thiaz-bala-betaipro
2354 : phhs-ithiadiaz-gly-betapytb2354: phhs-ithiadiaz-gly-betapytb
2355: 2pmhs-25thiaz-gly-betameph2355: 2 pmhs-25thiaz-gly-betameph
2356: bim-me24thioph-bala-psdap2356: bim-me24thioph-bala-psdap
2357: phhs-25thiaz-bala-betaphethio2357: phhs-25thiaz-bala-betaphethio
10 2358 : tolhs-oxadiaz-bala-betahbcph10 2358: tolhs-oxadiaz-bala-betahbcph
2359: bhs-26py-gly-psdap2359: bhs-26py-gly-psdap
2360: bhs-24thiaz-gly-betaanaphth2360: bhs-24thiaz-gly-betaanaphth
2361: dhim-2thioph-gly-betameph2361: dhim-2thioph-gly-betameph
2362 : 2py-me24thioph-leu-betadcph 15 2363: tolhs-24thiaz-bala-betabmph2362: 2py-me24thioph-leu-betadcph 15 2363: tolhs-24thiaz-bala-betabmph
2364: bhs-25oxaz-bala-beta35dbph2364: bhs-25oxaz-bala-beta35dbph
2365: tolhs-25methiaz-gly-betadhbfu2365: tolhs-25methiaz-gly-betadhbfu
2366: bhs-24thioph-bala-betafluo2366: bhs-24thioph-bala-betafluo
2367: tolhs-24thiaz-bala-betaol 20 2368: bim-24thioph-gly-betadbph2367: tolhs-24thiaz-bala-betaol 20 2368: bim-24thioph-gly-betadbph
2369: phhs-24thioph-bala-betabph2369: phhs-24thioph-bala-betabph
2370: phhs-nme35pyr-bala-betacbph2370: phhs-nme35pyr-bala-betacbph
2371 : tolhs-ithiadiaz-bala-betadhbfu2371: tolhs-ithiadiaz-bala-betadhbfu
2372: 2py-24oxaz-gly-betainyl2372: 2py-24oxaz-gly-betainyl
2373: ibhs-24thioph-gly-zdaptb2373: ibhs-24thioph-gly-zdaptb
25 2374: 2py-25fur-leu-betadcph25 2374: 2py-25fur-leu-betadcph
2375: bhs-24thiaz-gly-betaimid2375: bhs-24thiaz-gly-betaimide
2376: ibhs-25methiaz-bala-betal3bendi2376: ibhs-25methiaz-bala-betal3bendi
2377: bhs-24thiaz-bala-betapyr2377: bras-24thiaz-bala-betapyr
2378: ibhs-24thiaz-bala-suabu 30 2379: tolhs-oxadiaz-gly-betambiph2378: ibhs-24thiaz-bala-suabu 30 2379: tolhs-oxadiaz-gly-betambiph
2380: bhs-oxadiaz-nmgly-betathioph2380: bhs-oxadiaz-nmgly-betathioph
2381: phhs-25methiaz-gly-betabediox2381: phhs-25methiaz-gly-betabediox
2382: ibhs-25thiaz-gly-betameph2382: ibhs-25thiaz-gly-betameph
2383 : phhs-24thioph-bala-betaipro 35 2384: bhs-24chin-ala-betameph2383: phhs-24thioph-bala-betaipro 35 2384: bhs-24chin-ala-betameph
2385: tolhs-25oxaz-gly-betainyl2385: tolhs-25oxaz-gly-betainyl
2386: 2py-25oxaz-bala-betapy2386: 2py-25oxaz-bala-betapy
2387 : tolhs-25methiaz-gly-betacph2387: tolhs-25methiaz-gly-betacph
2388: ibhs-25oxaz-bala-betal3bendi2388: ibhs-25oxaz-bala-betal3bendi
2389: tolhs-25oxaz-gly-beta3quin2389: tolhs-25oxaz-gly-beta3quin
40 2390: ibhs-25oxaz-bala-zdap40 2390: ibhs-25oxaz-bala-zdap
2391 : tolhs-24thioph-bala-betal3bendi2391: tolhs-24thioph-bala-betal3bendi
2392: phhs-me24oxaz-bala-psdap2392: phhs-me24oxaz-bala-psdap
2393: bim-24thioph-bala-betatos2393: bim-24thioph-bala-betatos
2394: tolhs-me25oxaz-ala-zdap 45 2395: bhs-me24oxaz-bala-zdap2394: tolhs-me25oxaz-ala-zdap 45 2395: bhs-me24oxaz-bala-zdap
2396: bhs-25thiaz-bala-betadbph2396: bras-25thiaz-bala-betadbph
2397 : phhs-ithiadiaz-gly-betainyl 2398 : ibhs-ithiadiaz-gly-betapytb 2399: ibhs-24thiaz-gly-betah35dc 2400 : tolhs-24thiaz-gly-betatbuph 2401: phhs-24thiaz-bala-betampy 2402: bhs-53pyrazo-bala-betapy 2403: 2py-25oxaz-bala-betadcph 2404: phhs-me24thioph-leu-betapy 2405 : tolhs-ithiadiaz-bala-betaanaphth 2406: ibhs-oxadiaz-bala-betaph 2407: phhs-25methiaz-gly-betafu22397: phhs-ithiadiaz-gly-betainyl 2398: ibhs-ithiadiaz-gly-betapytb 2399: ibhs-24thiaz-gly-betah35dc 2400: tolhs-24thiaz-gly-betatbuph 2401: phhs-24thiaz-bala-betampy 2402: bhs-53pyrazo-bala-betapy 2403: 2py 253 -bala-betadcph 2404: phhs-me24thioph-leu-betapy 2405: tolhs-ithiadiaz-bala-betaanaphth 2406: ibhs-oxadiaz-bala-betaph 2407: phhs-25methiaz-gly-betafu2
10 2408: phhs-24thioph-gly-betadbph 2409: phhs-24thioph-bala-psdapee 2410: ibhs-24thiaz-bala-betacph 2411: bhs-me25thiaz-gly-betadcph 2412: phhs-oxadiaz-bala-betabpy10 2408: phhs-24thioph-gly-betadbph 2409: phhs-24thioph-bala-psdapee 2410: ibhs-24thiaz-bala-betacph 2411: bhs-me25thiaz-gly-betadcph 2412: phhs-oxadiaz-bala-betabpy
15 2413: ibhs-24thioph-gly-beta34dcph 2414: ibhs-25thiaz-gly-betapbiph 2415 : tolhs-24thiaz-bala-beta34meoph 2416 : tolhs-ithiadiaz-bala-betapbiph 2417: phhs-nme35pyr-bala-betadcph15 2413: ibhs-24thioph-gly-beta34dcph 2414: ibhs-25thiaz-gly-betapbiph 2415: tolhs-24thiaz-bala-beta34meoph 2416: tolhs-ithiadiaz-bala-betapbiph 2417: phhs-nme35pyr-bala-betadcph
20 2418: 2pmhs-25methiaz-gly-betathiome 2419: bhs-me25thiaz-bala-psdap 2420 : phhs-ithiadiaz-gly-betabenfu 2421: 2py-nme35pyr-leu-betadcph 2422: phhs-24thioph-bala-betadmph 2423 : bhs-24thioph-bala-betahcbph20 2418: 2 pmhs-25methiaz-gly-betathiome 2419: bhs-me25thiaz-bala-psdap 2420: phhs-ithiadiaz-gly-betabenfu 2421: 2py-nme35pyr-leu-betadcph 2422: phhs-24thioph-bala-betadmph 2423: 24thioph-bala-betahcbph
25 2424: 2py-25methiaz-bala-asppha 2425: 2py-26py-gly-betampy 2426: ibhs-nme35pyr-gly-zdapch 2427: tolhs-me24thiaz-ala-betapy 2428: tolhs-nme35pyr-gly-betapbiph25 2424: 2py-25methiaz-bala-asppha 2425: 2py-26py-gly-betampy 2426: ibhs-nme35pyr-gly-zdapch 2427: tolhs-me24thiaz-ala-betapy 2428: tolhs-nme35pyr-gly-betapbiph
30 2429: phhs-ithiadiaz-gly-betapyee 2430: bhs-25oxaz-gly-beta34meoph 2431: 2py-35thioph-leu-betadcph 2432: ibhs-n e35pyr-g1y-betabph 2433 : bhs-ithiadiaz-gly-betaphethio30 2429: phhs-ithiadiaz-gly-betapyee 2430: bhs-25oxaz-gly-beta34meoph 2431: 2py-35thioph-leu-betadcph 2432: ibhs-n e35pyr-g1y-betabph 2433: bhs-ithiadiaz-gly-betaphethio
35 2434: tolhs-25thiaz-gly-zdapch 2435: 2py-24thioph-ala-zdap 2436 : tolhs-ithiadiaz-gly-betahph 2437 : phhs-25methiaz-bala-betaphethioa 2438: ibhs-25oxaz-gly-betah35dc 2439 : gua-25thioph-gly-betaphethio35 2434: tolhs-25thiaz-gly-zdapch 2435: 2py-24thioph-ala-zdap 2436: tolhs-ithiadiaz-gly-betahph 2437: phhs-25methiaz-bala-betaphethioa 2438: ibhs-25oxaz-gly-betah35dc 2439: gua- 25thioph-gly-betaphethio
40 2440: bim-35fur-gly-psdap 2441 : ibhs-ithiadiaz-bala-betaftrif 2442 : tolhs-24thiaz-gly-beta34meoph 2443 : bhs-25methiaz-bala-betacthioph 2444 : bhs-nme35pyr-ala-betaoxaz40 2440: bim-35fur-gly-psdap 2441: ibhs-ithiadiaz-bala-betaftrif 2442: tolhs-24thiaz-gly-beta34meoph 2443: bhs-25methiaz-bala-betacthioph 2444: bhs-nme35pyr-ala-betaoxaz
45 2445: 2py-me24thioph-gly-zdap 2446: 2py-25oxaz-gly-betambiph 2447: bhs-42nmeim-gly-psdap 2448: bhs-oxadiaz-gly-psdapee45 2445: 2py-me24thioph-gly-zdap 2446: 2py-25oxaz-gly-betambiph 2447: bhs-42nmeim-gly-psdap 2448: bhs-oxadiaz-gly-psdapee
2449: phhs-ithiadiaz-gly-betafph2449: phhs-ithiadiaz-gly-betafph
2450 : thazep-42pym-gly-betal3bendi2450: thazep-42pym-gly-betal3bendi
2451: phhs-25methiaz-bala-betabmph2451: phhs-25methiaz-bala-betabmph
2452: bhs-25methiaz-bala-betapbiph2452: bras-25methiaz-bala-betapbiph
2453: phhs-nme35pyr-g1y-suabu2453: phhs-nme35pyr-g1y-suabu
2454 : ibhs-ithiadiaz-bala-betamethioph2454: ibhs-ithiadiaz-bala-betamethioph
2455: 2pmhs-24thioph-gly-betafph2455: 2 pmhs-24thioph-gly-betafph
2456: tolhs-24thiaz-gly-betacbph2456: tolhs-24thiaz-gly-betacbph
2457: phhs-25thiaz-bala-betathio32457: phhs-25thiaz-bala-betathio3
10 2458 : ibhs-oxadiaz-bala-betamethioph10 2458: ibhs-oxadiaz-bala-betamethioph
2459: ibhs-25thiaz-gly-aspibua2459: ibhs-25thiaz-gly-aspibua
2460: bhs-42nmeim-bala-betadcph2460: bras-42nmeim-bala-betadcph
2461 : phhs-25oxaz-bala-betaomebendi2461: phhs-25oxaz-bala-betaomebendi
2462: phhs-nme35pyr-gly-asppha2462: phhs-nme35pyr-gly-asppha
15 2463: ibhs-24thiaz-bala-betainyl15 2463: ibhs-24thiaz-bala-betainyl
2464: bim-25oxaz-gly-aspibua2464: bim-25oxaz-gly-aspibua
2465: bhs-ithiadiaz-ala-betafphe2465: bhs-ithiadiaz-ala-betafphe
2466: bhs-25oxaz-bala-betafphe2466: bras-25oxaz-bala-betafphe
2467 : ibhs-ithiadiaz-gly-betaibph2467: ibhs-ithiadiaz-gly-betaibph
20 2468: gua-26py-gly-betabnaphth20 2468: gua-26py-gly-betabnaphth
2469: ibhs-25oxaz-gly-betathioph2469: ibhs-25oxaz-gly-betathioph
2470 : phhs-25methiaz-gly-betathiobe2470: phhs-25methiaz-gly-betathiobe
2471: ibhs-24thiaz-gly-betadbph2471: ibhs-24thiaz-gly-betadbph
2472 : tolhs-ithiadiaz-gly-betabthioph2472: tolhs-ithiadiaz-gly-betabthioph
2473: bhs-oxadiaz-gly-busu2be2473: bhs-oxadiaz-gly-busu2be
25 2474 : phhs-24thioph-gly-betaphethioa25 2474: phhs-24thioph-gly-betaphethioa
2475: bhs-24thiaz-ala-betameph2475: bhs-24thiaz-ala-betameph
2476: tolhs-25thiaz-bala-betaol2476: tolhs-25thiaz-bala-betaol
2477 : bhs-ithiadiaz-bala-betahmofu2477: bhs-ithiadiaz-bala-betahmofu
2478: phhs-ithiadiaz-bala-betaph2478: phhs-ithiadiaz-bala-betaph
30 2479: bhs-35fur-gly-betapy30 2479: bhs-35fur-gly-betapy
2480 : ibhs-24thioph-bala-betapych2480: ibhs-24thioph-bala-betapych
2481: phhs-25oxaz-gly-betal3bendi2481: phhs-25oxaz-gly-betal3bendi
2482: bhs-25thiaz-ala-betadito2482: bras-25thiaz-ala-betadito
2483: bhs-ithiadiaz-bala-psdap2483: bhs-ithiadiaz-bala-psdap
35 2484: bim-24thioph-bala-betaipro35 2484: bim-24thioph-bala-betaipro
2485: phhs-24thioph-bala-beta34dcph2485: phhs-24thioph-bala-beta34dcph
2486 : tolhs-me24thioph-leu-betapy2486: tolhs-me24thioph-leu-betapy
2487: phhs-25methiaz-gly-betahmph2487: phhs-25methiaz-gly-betahmph
2488 : tolhs-oxadiaz-gly-betatbuph2488: tolhs-oxadiaz-gly-betatbuph
2489: bhs-me24thioph-bala-zdap2489: bhs-me24thioph-bala-zdap
40 2490: phhs-24thioph-gly-betahmo40 2490: phhs-24thioph-gly-betahmo
2491 : bhs-nme35pyr-gly-betabmph2491: bhs-nme35pyr-gly-betabmph
2492: bim-24thioph-gly-zdap2492: bim-24thioph-gly-zdap
2493: ibhs-25thiaz-bala-betahc2493: ibhs-25thiaz-bala-betahc
2494: ibhs-ithiadiaz-bala-zdaptb2494: ibhs-ithiadiaz-bala-zdaptb
45 2495: bhs-24thiaz-gly-betadcphee45 2495: bras-24thiaz-gly-betadcphee
2496 : ibhs-24thioph-bala-betacbph2496: ibhs-24thioph-bala-betacbph
2497: ibhs-ithiadiaz-bala-betaph 2498 : ibhs-25methiaz-gly-betahdcph 2499: phhs-24thiaz-bala-betafbph 2500: phhs-25oxaz-gly-betadhbfu2497: ibhs-ithiadiaz-bala-betaph 2498: ibhs-25methiaz-gly-betahdcph 2499: phhs-24thiaz-bala-betafbph 2500: phhs-25oxaz-gly-betadhbfu
2501: bhs-42oxaz-leu-zdap 5 2502: phhs-ithiadiaz-gly-betaomebendi2501: bhs-42oxaz-leu-zdap 5 2502: phhs-ithiadiaz-gly-betaomebendi
2503: phhs-24thiaz-bala-beta4bph2503: phhs-24thiaz-bala-beta4bph
2504: bhs-24thioph-bala-betaipro2504: bhs-24thioph-bala-betaipro
2505: phhs-oxadiaz-bala-betahc2505: phhs-oxadiaz-bala-betahc
2506: tolhs-25oxaz-bala-betadito2506: tolhs-25oxaz-bala-betadito
2507: bhs-nme35pyr-gly-betapbiph2507: bhs-nme35pyr-gly-betapbiph
10 2508: bhε-25methiaz-gly-betameph10 2508: bhε-25methiaz-gly-betameph
2509: ibhs-25oxaz-bala-beta4bph2509: ibhs-25oxaz-bala-beta4bph
2510 : ibhs-ithiadiaz-bala-betadtrif2510: ibhs-ithiadiaz-bala-betadtrif
2511: bhs-ithiadiaz-gly-betabph2511: bhs-ithiadiaz-gly-betabph
2512 : bhs-25oxaz-bala-betal3bendi 15 2513: tolhs-25oxaz-bala-betafluo2512: bhs-25oxaz-bala-betal3bendi 15 2513: tolhs-25oxaz-bala-betafluo
2514: tolhs-25thiaz-bala-aspibua2514: tolhs-25thiaz-bala-aspibua
2515: ibhs-24thiaz-gly-betapytb2515: ibhs-24thiaz-gly-betapytb
2516: tolhs-me25oxaz-leu-psdap2516: tolhs-me25oxaz-leu-psdap
2517 : phhs-25methiaz-bala-betahph 20 2518: bhs-24thioph-ala-betadhbfu2517: phhs-25methiaz-bala-betahph 20 2518: bhs-24thioph-ala-betadhbfu
2519: bim-24thiaz-phg-zdap2519: bim-24thiaz-phg-zdap
2520: bhs-me25thiaz-bala-betapy2520: bhs-me25thiaz-bala-betapy
2521: 2py-35fur-bala-psdap2521: 2py-35fur-bala-psdap
2522 : phhs-me25thioph-ala-betadcph2522: phhs-me25thioph-ala-betadcph
2523: bhs-me25thiaz-gly-betaph2523: bhs-me25thiaz-gly-betaph
2525
2524: phhs-25thiaz-gly-asppha2524: phhs-25thiaz-gly-asppha
2525: phhs-25methiaz-gly-betadcphtb2525: phhs-25methiaz-gly-betadcphtb
2526: ibhs-nme35pyr-bala-betapbiph2526: ibhs-nme35pyr-bala-betapbiph
2527 : phhs-ithiadiaz-gly-betadtrif2527: phhs-ithiadiaz-gly-betadtrif
2528: bhs-24thiaz-gly-betabdimo 30 2529: bhs-25methiaz-ala-betabnaphth2528: bhs-24thiaz-gly-betabdimo 30 2529: bhs-25methiaz-ala-betabnaphth
2530: 2py-me25thiaz-leu-zdap2530: 2py-me25thiaz-leu-zdap
2531: ibhs-24thiaz-gly-betaipr2531: ibhs-24thiaz-gly-betaipr
2532: dhim-25thioph-gly-betahcbph2532: dhim-25thioph-gly-betahcbph
2533 : tolhs-me24thiaz-leu-beta34meoph 35 2534: bhs-25thiaz-bala-betaipro2533: tolhs-me24thiaz-leu-beta34meoph 35 2534: bhs-25thiaz-bala-betaipro
2535: bim-me24thiaz-ala-psdap2535: bim-me24thiaz-ala-psdap
2536: gua-25thioph-gly-betapbiph2536: gua-25thioph-gly-betapbiph
2537: 2pmhs-24thioph-gly-betaph2537: 2 pmhs-24thioph-gly-betaph
2538: bhs-24thioph-bala-betaibph2538: bhs-24thioph-bala-betaibph
2539 : tolhs-24thioph-bala-betabnaphth2539: tolhs-24thioph-bala-betabnaphth
40 2540: bhs-nme35pyr-bala-betampy40 2540: bhs-nme35pyr-bala-betampy
2541: bim-ithiadiaz-bala-aspbzla2541: bim-ithiadiaz-bala-aspbzla
2542: ur-25thioph-gly-zdap2542: ur-25thioph-gly-zdap
2543: bhs-24thioph-gly-betatos2543: bhs-24thioph-gly-betatos
2544: bhs-nme35pyr-gly-aspaba 45 2545: tolhs-ithiadiaz-gly-zdapch2544: bhs-nme35pyr-gly-aspaba 45 2545: tolhs-ithiadiaz-gly-zdapch
2546: ibhs-24thioph-gly-betapyr2546: ibhs-24thioph-gly-betapyr
2547 : bhs-ithiadiaz-bala-betaibph 2548: bhs-25methiaz-bala-betathiobe2547: bhs-ithiadiaz-bala-betaibph 2548: bras-25methiaz-bala-betathiobe
2549 : ibhs-25thiaz-bala-betal3bendi2549: ibhs-25thiaz-bala-betal3bendi
2550: bhs-24thioph-ala-betainyl2550: bhs-24thioph-ala-betainyl
2551: 2pmhs-25oxaz-gly-betadito 5 2552: tolhs-oxadiaz-bala-ibsdap2551: 2 pmhs-25oxaz-gly-betadito 5 2552: tolhs-oxadiaz-bala-ibsdap
2553: bim-me24oxaz-leu-betadcph2553: bim-me24oxaz-leu-betadcph
2554: phhs-25thiaz-bala-betainyl2554: phhs-25thiaz-bala-betainyl
2555: phhs-me24oxaz-bala-betaph2555: phhs-me24oxaz-bala-betaph
2556: bhs-23thioph-gly-betapy2556: bhs-23thioph-gly-betapy
2557 : tolhs-25methiaz-bala-betafbph2557: tolhs-25methiaz-bala-betafbph
1010
2558: bhs-oxadiaz-bala-betabenfu2558: bras-oxadiaz-bala-betabenfu
2559: phhs-24thiaz-gly-betadcph2559: phhs-24thiaz-gly-betadcph
2560 : phhs-25oxaz-gly-betaomebendi2560: phhs-25oxaz-gly-betaomebendi
2561: tolhs-nme35pyr-gly-betadcph2561: tolhs-nme35pyr-gly-betadcph
2562: ibhs-24thioph-bala-zdapch 15 2563: tolhs-nme35pyr-gly-betah35dc2562: ibhs-24thioph-bala-zdapch 15 2563: tolhs-nme35pyr-gly-betah35dc
2564: ibhs-25thiaz-gly-betabthioph2564: ibhs-25thiaz-gly-betabthioph
2565: tolhs-24thioph-gly-betabediox2565: tolhs-24thioph-gly-betabediox
2566: bhs-25thiaz-gly-betathiobe2566: bhs-25thiaz-gly-betathiobe
2567: phhs-oxadiaz-bala-beta3quin 20 2568: ibhs-25thiaz-gly-betaph2567: phhs-oxadiaz-bala-beta3quin 20 2568: ibhs-25thiaz-gly-betaph
2569: phhs-25thiaz-gly-betampy2569: phhs-25thiaz-gly-betampy
2570: ibhs-nme35pyr-gly-betabdimo2570: ibhs-nme35pyr-gly-betabdimo
2571: 2py-25methiaz-hphe-psdap2571: 2py-25methiaz-hphe-psdap
2572: phhs-ithiadiaz-gly-betahni2572: phhs-ithiadiaz-gly-betahni
2573: bhs-nme35pyr-ala-betafphe2573: bhs-nme35pyr-ala-betafphe
25 2574: 2py-52thiaz-ala-betameph25 2574: 2py-52thiaz-ala-betameph
2575: gua-24thiaz-gly-betafph2575: gua-24thiaz-gly-betafph
2576 : ibhs-24thioph-bala-beta4bph2576: ibhs-24thioph-bala-beta4bph
2577: bhs-24thiaz-bala-betaheph2577: bhs-24thiaz-bala-betaheph
2578: ibhs-25methiaz-gly-betaph 30 2579: phhs-nme35pyr-gly-betahcbph2578: ibhs-25methiaz-gly-betaph 30 2579: phhs-nme35pyr-gly-betahcbph
2580: phhs-ithiadiaz-bala-betah35dc2580: phhs-ithiadiaz-bala-betah35dc
2581 : bhs-oxadiaz-bala-beta23meoph2581: bhs-oxadiaz-bala-beta23meoph
2582: bim-25thiaz-gly-betaibph2582: bim-25thiaz-gly-betaibph
2583 : tolhs-25methiaz-bala-beta34dcph 35 2584: tolhs-24thioph-gly-zdapee2583: tolhs-25methiaz-bala-beta34dcph 35 2584: tolhs-24thioph-gly-zdapee
2585: tolhs-oxadiaz-gly-betahmo2585: tolhs-oxadiaz-gly-betahmo
2586: 4pmhs-24oxaz-gly-betameph2586: 4 pmhs-24oxaz-gly-betameph
2587 : ibhs-ithiadiaz-bala-betafbph2587: ibhs-ithiadiaz-bala-betafbph
2588: bhs-oxadiaz-bala-betaftrif2588: bras-oxadiaz-bala-betaftrif
2589: gua-24oxaz-gly-betafu22589: gua-24oxaz-gly-betafu2
40 2590 : tolhs-me24thiaz-gly-betadcph40 2590: tolhs-me24thiaz-gly-betadcph
2591 : bhs-25thiaz-bala-betathiome2591: bhs-25thiaz-bala-betathiome
2592: impy-25oxaz-gly-be ameph2592: impy-25oxaz-gly-be ameph
2593: ibhs-25thiaz-bala-betafbph2593: ibhs-25thiaz-bala-betafbph
2594 : tolhs-24thiaz-bala-betaipro 45 2595: tolhs-25oxaz-bala-betapytb2594: tolhs-24thiaz-bala-betaipro 45 2595: tolhs-25oxaz-bala-betapytb
2596: bim-me24thioph-leu-betapy2596: bim-me24thioph-leu-betapy
2597 : tolhs-24thioph-gly-betaphethio 2598: 2py-25thioph-gly-psdap2597: tolhs-24thioph-gly-betaphethio 2598: 2py-25thioph-gly-psdap
2599: bhs-25thiaz-gly-betahmo2599: bhs-25thiaz-gly-betahmo
2600: tolhs-oxadiaz-bala-aspaba2600: tolhs-oxadiaz-bala-aspaba
2601: bhs-oxadiaz-leu-zdap 5 2602: hs-24thiaz-bala-betapy2601: bhs-oxadiaz-leu-zdap 5 2602: hs-24thiaz-bala-betapy
2603: bhs-25thiaz-gly-betaoxope2603: bhs-25thiaz-gly-betaoxope
2604: bhs-24thioph-bala-betathioph2604: bhs-24thioph-bala-betathioph
2605: tolhs-ithiadiaz-bala-betabpy2605: tolhs-ithiadiaz-bala-betabpy
2606: phhs-ithiadiaz-gly-betamethi2606: phhs-ithiadiaz-gly-betamethi
2607: phhs-24thiaz-gly-betatrif2607: phhs-24thiaz-gly-betatrif
2608: ibhs-nme35pyr-gly-betahmph2608: ibhs-nme35pyr-gly-betahmph
2609: phhs-25oxaz-bala-betacbph2609: phhs-25oxaz-bala-betacbph
2610: tolhs-25thiaz-gly-asppha2610: tolhs-25thiaz-gly-asppha
2611: bhs-25thiaz-bala-betahc2611: bras-25thiaz-bala-betahc
2612: tolhs-25thiaz-gly-betaph 15 2613: bhs-ithiadiaz-gly-zdapee2612: tolhs-25thiaz-gly-betaph 15 2613: bhs-ithiadiaz-gly-zdapee
2614: bhs-25oxaz-bala-betamesu2614: bras-25oxaz-bala-betamesu
2615: bhs-nme35pyr-gly-betahc2615: bhs-nme35pyr-gly-betahc
2616: tolhs-me25thiaz-gly-betapy2616: tolhs-me25thiaz-gly-betapy
2617: bhs-oxadiaz-bala-betafph 20 2618: bim-nme35pyr-leu-betadcph2617: bras-oxadiaz-bala-betafph 20 2618: bim-nme35pyr-leu-betadcph
2619: tolhs-nme35pyr-bala-betamesu2619: tolhs-nme35pyr-bala-betamesu
2620: dhim-25thiaz-gly-betameph2620: dhim-25thiaz-gly-betameph
2621 : tolhs-me25thioph-ala-betapy2621: tolhs-me25thioph-ala-betapy
2622: ibhs-oxadiaz-bala-betaamibe2622: ibhs-oxadiaz-bala-betaamibe
2623 : impy-24thiaz-gly-betabthioph2623: impy-24thiaz-gly-betabthioph
2624: ibhs-25oxaz-bala-betaph2624: ibhs-25oxaz-bala-betaph
2625: bhs-25methiaz-gly-betapych2625: bhs-25methiaz-gly-betapych
2626: bhs-25methiaz-gly-betambiph2626: bhs-25methiaz-gly-betambiph
2627: tolhs-25oxaz-gly-betadtrif2627: tolhs-25oxaz-gly-betadtrif
2628: bhs-25methiaz-nmgly-betadmph 30 2629: bhs-25thiaz-ala-betabpy2628: bhs-25methiaz-nmgly-betadmph 30 2629: bhs-25thiaz-ala-betabpy
2630: ibhs-25oxaz-gly-betacthioph2630: ibhs-25oxaz-gly-betacthioph
2631 : 2py-24thioph-gly-betacthioph2631: 2py-24thioph-gly-betacthioph
2632 : bhs-24thioph-gly-betadcphee2632: bhs-24thioph-gly-betadcphee
2633: ibhs-25oxaz-gly-betadbph 35 2634: phhs-24thiaz-gly-betapym2633: ibhs-25oxaz-gly-betadbph 35 2634: phhs-24thiaz-gly-betapym
2635: tolhs-nme35pyr-bala-betathiome2635: tolhs-nme35pyr-bala-betathiome
2636: bhs-ithiadiaz-ala-betadmph2636: bhs-ithiadiaz-ala-betadmph
2637: bhs-25thiaz-bala-betahmo2637: bras-25thiaz-bala-betahmo
2638: bhs-25methiaz-nmgly-betahph2638: bhs-25methiaz-nmgly-betahph
2639: tolhs-nme35pyr-gly-betameph2639: tolhs-nme35pyr-gly-betameph
40 2640: ibhs-25methιaz-gly-betaomebendi40 2640: ibhs-25methιaz-gly-betaomebendi
2641: bim-25oxaz-bala-beta4bph2641: bim-25oxaz-bala-beta4bph
2642: 2py-24thiaz-gly-betainyl2642: 2py-24thiaz-gly-betainyl
2643: bhs-ithiadiaz-bala-betaipr2643: bhs-ithiadiaz-bala-betaipr
2644: bhs-25thiaz-bala-betahdbph2644: bhs-25thiaz-bala-betahdbph
45 2645: ibhs-25oxaz-gly-betahcbph45 2645: ibhs-25oxaz-gly-betahcbph
2646 : tolhs-24thiaz-bala-betaibph2646: tolhs-24thiaz-bala-betaibph
2647: 2py-25fur-gly-psdap 2648: phhs-25thiaz-bala-betaph 2649: bhs-24thiaz-gly-betapy 2650 : ibhs-nme35pyr-bala-betabthioph 2651 : tolhs-ithiadiaz-gly-betainyl 5 2652: dhpyrr-42nmeim-gly-zdap2647: 2py-25fur-gly-psdap 2648: phhs-25thiaz-bala-betaph 2649: bhs-24thiaz-gly-betapy 2650: ibhs-nme35pyr-bala-betabthioph 2651: tolhs-ithiadiaz-gly-betainyl 5 2652: dhpyrr-42nmeim-gly-zdap
2653: bhs-nme35pyr-gly-csdap2653: bhs-nme35pyr-gly-csdap
2654: gua-25thiaz-gly-betatos2654: gua-25thiaz-gly-betatos
2655: bhs-24thioph-gly-betatbuph2655: bhs-24thioph-gly-betatbuph
2656: ibhs-25oxaz-bala-betatbuph2656: ibhs-25oxaz-bala-betatbuph
2657: bhs-25thiaz-bala-betabenfu2657: bras-25thiaz-bala-betabenfu
10 2658: ibhs-nme35pyr-g1y-betapy10 2658: ibhs-nme35pyr-g1y-betapy
2659: 2py-26py-gly-ibsdap2659: 2py-26py-gly-ibsdap
2660: 2py-24thiaz-bala-aspibua2660: 2py-24thiaz-bala-aspibua
2661: bhs-oxadiaz-gly-betabediox2661: bhs-oxadiaz-gly-betabediox
2662: phhs-nme35pyr-bala-betafu2 15 2663: bhs-thiadiaz-ala-betadcph2662: phhs-nme35pyr-bala-betafu2 15 2663: bhs-thiadiaz-ala-betadcph
2664: bhs-oxadiaz-bala-betaheph2664: bhs-oxadiaz-bala-betaheph
2665 : bhs-25thiaz-gly-beta34meoph2665: bhs-25thiaz-gly-beta34meoph
2666: bhs-25methiaz-bala-betadmph2666: bras-25methiaz-bala-betadmph
2667: bhs-25thiaz-bala-betaftrif 20 2668: ibhs-24oxaz-gly-zdap2667: bhs-25thiaz-bala-betaftrif 20 2668: ibhs-24oxaz-gly-zdap
2669: tolh.s-ithiadiaz-bala-betah.35dc2669: tolh.s-ithiadiaz-bala-betah.35dc
2670: 2py-24thiaz-bala-betafluo2670: 2py-24thiaz-bala-betafluo
2671: agua-24thiaz-gly-betainyl2671: agua-24thiaz-gly-betainyl
2672: bim-25methiaz-bala-aspaba2672: bim-25methiaz-bala-aspaba
2673: bhs-25thiaz-gly-betahmph2673: bhs-25thiaz-gly-betahmph
25 2674: phhs-25thiaz-bala-betaet25 2674: phhs-25thiaz-bala-betet
2675: bhs-25thiaz-bala-psdapch2675: bhs-25thiaz-bala-psdapch
2676: phhs-oxadiaz-gly-betadcph2676: phhs-oxadiaz-gly-betadcph
2677: 2py-42nmeim-nmala-betapy2677: 2py-42nmeim-nmala-betapy
2678: ibhs-26py-gly-betainyl 30 2679: phhs-25methiaz-gly-ibsdap2678: ibhs-26py-gly-betainyl 30 2679: phhs-25methiaz-gly-ibsdap
2680: bim-42pym-ala-psdap2680: bim-42pym-ala-psdap
2681: phhs-24thiaz-bala-betahph2681: phhs-24thiaz-bala-betahph
2682 : tolhs-24thioph-gly-betabdimo2682: tolhs-24thioph-gly-betabdimo
2683: ibhs-25oxaz-bala-betatrif 35 2684: bhs-nme35pyr-ala-zdap2683: ibhs-25oxaz-bala-betatrif 35 2684: bhs-nme35pyr-ala-zdap
2685: bhs-25fur-bala-betapy2685: bras-25fur-bala-betapy
2686 : phhs-24thioph-gly-betabnaphth2686: phhs-24thioph-gly-betabnaphth
2687 : tolhs-nme35pyr-bala-betathioph2687: tolhs-nme35pyr-bala-betathioph
2688 : phhs-25methiaz-bala-betaamibe2688: phhs-25methiaz-bala-betaamibe
2689 : tolhs-24thiaz-bala-betafbph2689: tolhs-24thiaz-bala-betafbph
40 2690: ibhs-oxadiaz-gly-psdaptb40 2690: ibhs-oxadiaz-gly-psdaptb
2691: tolhs-nme35pyr-gly-suabu2691: tolhs-nme35pyr-gly-suabu
2692: tolhs-25methiaz-gly-betabnaphth2692: tolhs-25methiaz-gly-betabnaphth
2693 : bhs-25oxaz-nmgly-betabnaphth2693: bhs-25oxaz-nmgly-betabnaphth
2694: ibhs-25thiaz-bala-betapytb 45 2695: tolhs-nme35pyr-bala-psdapee2694: ibhs-25thiaz-bala-betapytb 45 2695: tolhs-nme35pyr-bala-psdapee
2696: 2py-24thioph-gly-betadcph2696: 2py-24thioph-gly-betadcph
2697: sabhs-25thiaz-ala-betameph 2698: bhs-25methiaz-gly-betathio3 2699: ibhs-25methiaz-gly-psdaptb 2700 : bhs-nme35pyr-gly-betapym 2701: ibhs-25thiaz-gly-ibsdap 5 2702: impy-25methiaz-bala-betaftrif2697: sabhs-25thiaz-ala-betameph 2698: bhs-25methiaz-gly-betathio3 2699: ibhs-25methiaz-gly-psdaptb 2700: bhs-nme35pyr-gly-betapym 2701: ibhs-25thiaz-gly-ibsdap 5 2702: impy-25methiaz-bala-betaftrif
2703 : tolhs-25methiaz-gly-betafluo2703: tolhs-25methiaz-gly-betafluo
2704: ibhs-25oxaz-bala-betaoxope2704: ibhs-25oxaz-bala-betaoxope
2705: gua-26py-gly-betafbph2705: gua-26py-gly-betafbph
2706: bhs-nme35pyr-bala-betahb2706: bhs-nme35pyr-bala-betahb
2707: ibhs-nme35pyr-bala-betapyee2707: ibhs-nme35pyr-bala-betapyee
10 2708: bhs-24oxaz-bala-psdap10 2708: bras-24oxaz-bala-psdap
2709: bhs-25oxaz-bala-betahdbph2709: bras-25oxaz-bala-betahdbph
2710: phhs-25oxaz-bala-zdap2710: phhs-25oxaz-bala-zdap
2711: phhs-25methiaz-gly-betah35dc2711: phhs-25methiaz-gly-betah35dc
2712: ibhs-25thiaz-bala-betacph 15 2713: tolhs-25thiaz-gly-betaamibe2712: ibhs-25thiaz-bala-betacph 15 2713: tolhs-25thiaz-gly-betaamibe
2714: bhs-ithiadiaz-bala-betahmo2714: bhs-ithiadiaz-bala-betahmo
2715: tolhs-24thiaz-gly-suabu2715: tolhs-24thiaz-gly-suabu
2716: phhs-nme35pyr-gly-betaol2716: phhs-nme35pyr-gly-betaol
2717 : phhs-24thiaz-bala-betapbiph 20 2718: bhs-oxadiaz-nmgly-betadito2717: phhs-24thiaz-bala-betapbiph 20 2718: bhs-oxadiaz-nmgly-betadito
2719 : tolhs-ithiadiaz-gly-betaanaphth2719: tolhs-ithiadiaz-gly-betaanaphth
2720: tolhs-25thiaz-gly-busu2be2720: tolhs-25thiaz-gly-busu2be
2721: bim-24im-ala-betadcph2721: bim-24im-ala-betadcph
2722: ibhs-25thiaz-gly-betahmofu2722: ibhs-25thiaz-gly-betahmofu
2723 : tolhs-oxadiaz-bala-betaomebendi2723: tolhs-oxadiaz-bala-betaomebendi
25 2724 : bhs-ithiadiaz-gly-betadtrif25 2724: bhs-ithiadiaz-gly-betadtrif
2725 : ibhs-25methiaz-gly-betathioph2725: ibhs-25methiaz-gly-betathioph
2726: phhs-25methiaz-bala-betahdbph2726: phhs-25methiaz-bala-betahdbph
2727: bhs-nme35pyr-bala-betaol2727: bhs-nme35pyr-bala-betaol
2728: gua-26py-gly-betahc 30 2729: ibhs-25oxaz-bala-beta34meoph2728: gua-26py-gly-betahc 30 2729: ibhs-25oxaz-bala-beta34meoph
2730 : bim-25methiaz-bala-betahcbph2730: bim-25methiaz-bala-betahcbph
2731: phhs-nme35pyr-bala-betafph2731: phhs-nme35pyr-bala-betafph
2732: tolhs-25oxaz-bala-betaet2732: tolhs-25oxaz-bala-betaet
2733: 2py-nme35pyr-gly-betadcph 35 2734: tolhs-oxadiaz-gly-betaol2733: 2py-nme35pyr-gly-betadcph 35 2734: tolhs-oxadiaz-gly-betaol
2735: bhs-24im-ala-zdap2735: bhs-24im-ala-zdap
2736: 2py-35thioph-gly-betadcph2736: 2py-35thioph-gly-betadcph
2737: tolhs-25methiaz-gly-psdapee2737: tolhs-25methiaz-gly-psdapee
2738: impy-25methiaz-bala-psdap2738: impy-25methiaz-bala-psdap
2739 : ibhs-25methiaz-bala-betabediox2739: ibhs-25methiaz-bala-betabediox
40 2740 : tolhs-nme35pyr-bala-betaphethioa40 2740: tolhs-nme35pyr-bala-betaphethioa
2741 : tolhs-ithiadiaz-gly-betahbcph2741: tolhs-ithiadiaz-gly-betahbcph
2742: thazep-24thioph-bala-zdap2742: thazep-24thioph-bala-zdap
2743: dhim-25py-gly-betameph2743: dhim-25py-gly-betameph
2744: 2py-25fur-gly-betapy 45 2745: impy-42nmeim-gly-betabmph2744: 2py-25fur-gly-betapy 45 2745: impy-42nmeim-gly-betabmph
2746 : tolhs-24thioph-gly-betacbph2746: tolhs-24thioph-gly-betacbph
2747: phhs-oxadiaz-bala-betaf rif 2748: tolhs-25thiaz-bala-betacph2747: phhs-oxadiaz-bala-betaf rif 2748: tolhs-25thiaz-bala-betacph
2749: phhs-24thiaz-bala-betadito2749: phhs-24thiaz-bala-betadito
2750: bhs-25fur-ala-betapy2750: bhs-25fur-ala-betapy
2751: ibhs-25oxaz-gly-betahb 5 2752: tolhs-24thiaz-bala-zdapee2751: ibhs-25oxaz-gly-betahb 5 2752: tolhs-24thiaz-bala-zdapee
2753: bhs-25oxaz-gly-betahmo2753: bhs-25oxaz-gly-betahmo
2754: gua-24thiaz-gly-betamethioph2754: gua-24thiaz-gly-betamethioph
2755: nmhs-24thiaz-gly-betapy2755: nmhs-24thiaz-gly-betapy
2756: phhs-25thiaz-gly-betafph2756: phhs-25thiaz-gly-betafph
2757: tolhs-25oxaz-gly-betadmoph2757: tolhs-25oxaz-gly-betadmoph
1010
2758: phhs-oxadiaz-bala-betaet2758: phhs-oxadiaz-bala-betet
2759: bhs-24thiaz-gly-psdapee2759: bhs-24thiaz-gly-psdapee
2760: ibhs-24thiaz-bala-betabediox2760: ibhs-24thiaz-bala-betabediox
2761: gua-24thiaz-gly-betafu32761: gua-24thiaz-gly-betafu3
2762: tolhs-nme35pyr-bala-betaphethio 15 2763: ibhs-24thioph-gly-psdap2762: tolhs-nme35pyr-bala-betaphethio 15 2763: ibhs-24thioph-gly-psdap
2764: tolhs-me24oxaz-leu-beta34meoph2764: tolhs-me24oxaz-leu-beta34meoph
2765: 2py-24thioph-bala-aspaba2765: 2py-24thioph-bala-aspaba
2766: bim-me24oxaz-leu-psdap2766: bim-me24oxaz-leu-psdap
2767: bhs-nme35pyr-bala-betamesu 20 2768: bhs-thiadiaz-gly-zdap2767: bhs-nme35pyr-bala-betamesu 20 2768: bhs-thiadiaz-gly-zdap
2769: 2py-oxadiaz-ala-zdap2769: 2py-oxadiaz-ala-zdap
2770 : bim-25methiaz-gly-betapbiph2770: bim-25methiaz-gly-betapbiph
2771 : ibhs-24thioph-gly-betadcphee2771: ibhs-24thioph-gly-betadcphee
2772 : tolhs-nme35pyr-bala-betahdcph2772: tolhs-nme35pyr-bala-betahdcph
2773 : bhs-me24thioph-gly-betadcph2773: bhs-me24thioph-gly-betadcph
25 2774: phhs-25thiaz-bala-zdapch25 2774: phhs-25thiaz-bala-zdapch
2775: bhs-25thiaz-gly-betapych2775: bhs-25thiaz-gly-betapych
2776 : bhs-ithiadiaz-bala-betahdbph2776: bhs-ithiadiaz-bala-betahdbph
2777: impy-24thiaz-nmgly-psdap2777: impy-24thiaz-nmgly-psdap
2778: bim-25oxaz-bala-betal3bendi 30 2779: bim-oxadiaz-bala-betapy2778: bim-25oxaz-bala-betal3bendi 30 2779: bim-oxadiaz-bala-betapy
2780: tolhs-24thiaz-bala-betahdcph2780: tolhs-24thiaz-bala-betahdcph
2781: 2py-nme35pyr-ala-psdap2781: 2py-nme35pyr-ala-psdap
2782: ibhs-25thiaz-gly-betadtrif2782: ibhs-25thiaz-gly-betadtrif
2783: phhs-25thiaz-gly-betahbcph 35 2784: ibhs-oxadiaz-bala-zdapch2783: phhs-25thiaz-gly-betahbcph 35 2784: ibhs-oxadiaz-bala-zdapch
2785: dhim-26py-hphe-zdap2785: dhim-26py-hphe-zdap
2786: phhs-nme35pyr-gly-betahbcph2786: phhs-nme35pyr-gly-betahbcph
2787: bhs-25thiaz-bala-betafluo2787: bhs-25thiaz-bala-betafluo
2788: ibhs-oxadiaz-gly-beta3quin2788: ibhs-oxadiaz-gly-beta3quin
2789: 2py-35fur-bala-betadcph2789: 2py-35fur-bala-betadcph
40 2790: 2py-me25oxaz-gly-betadcph40 2790: 2py-me25oxaz-gly-betadcph
2791: bhs-24thiaz-gly-betaipr2791: bhs-24thiaz-gly-betaipr
2792 : bhs-25methiaz-bala-betabediox2792: bhs-25methiaz-bala-betabediox
2793: ibhs-ithiadiaz-gly-betaph2793: ibhs-ithiadiaz-gly-betaph
2794: phhs-25thiaz-bala-aspibua 45 2795: tolhs-oxadiaz-bala-betabdimo2794: phhs-25thiaz-bala-aspibua 45 2795: tolhs-oxadiaz-bala-betabdimo
2796: 2py-me24thiaz-ala-betapy2796: 2py-me24thiaz-ala-betapy
2797: impy-25methiaz-ala-betapy 2798 : phhs-nme35pyr-bala-betabnaphth 2799: bim-me25oxaz-leu-betapy 2800: gua-me24thiaz-gly-betapy2797: impy-25methiaz-ala-betapy 2798: phhs-nme35pyr-bala-betabnaphth 2799: bim-me25oxaz-leu-betapy 2800: gua-me24thiaz-gly-betapy
2801: 2py-24im-gly-betapy 5 2802: bhs-25thiaz-bala-betapbiph2801: 2py-24im-gly-betapy 5 2802: bhs-25thiaz-bala-betapbiph
2803: bhs-24thioph-bala-ibsdap2803: bhs-24thioph-bala-ibsdap
2804: 2py-35thioph-leu-betapy2804: 2py-35thioph-leu-betapy
2805: bhs-25thiaz-ala-beta3quin2805: bhs-25thiaz-ala-beta3quin
2806: ibhs-24thioph-bala-csdap2806: ibhs-24thioph-bala-csdap
2807: bhs-53pyrazo-bala-zdap2807: bras-53pyrazo-bala-zdap
1010
2808: bhs-42nmeim-gly-betapy2808: bhs-42nmeim-gly-betapy
2809: phhs-25oxaz-gly-betathioph2809: phhs-25oxaz-gly-betathioph
2810: ibhs-25methiaz-gly-betabpy2810: ibhs-25methiaz-gly-betabpy
2811: ibhs-24thiaz-bala-betapyee2811: ibhs-24thiaz-bala-betapyee
2812: bhs-25thiaz-nmgly-betaipro 15 2813: bhs-25methiaz-bala-betampy2812: bhs-25thiaz-nmgly-betaipro 15 2813: bhs-25methiaz-bala-betampy
2814: bhs-24thioph-bala-betamesu2814: bras-24thioph-bala-betamesu
2815: bim-me24oxaz-bala-zdap2815: bim-me24oxaz-bala-zdap
2816: bhs-25methiaz-gly-betaph2816: bhs-25methiaz-gly-betaph
2817: bim-25thiaz-gly-zdap 20 2818: bhs-nme35pyr-gly-betatbuph2817: bim-25thiaz-gly-zdap 20 2818: bhs-nme35pyr-gly-betatbuph
2819: bhs-25oxaz-ala-betadhbfu2819: bhs-25oxaz-ala-betadhbfu
2820 : ibhs-ithiadiaz-bala-betaphethioa2820: ibhs-ithiadiaz-bala-betaphethioa
2821: bhs-oxadiaz-gly-betathiome2821: bhs-oxadiaz-gly-betathioma
2822 : phhs-24thioph-bala-betabediox2822: phhs-24thioph-bala-betabediox
2823 : bhs-25thiaz-bala-betathioph2823: bhs-25thiaz-bala-betathioph
25 2824: phhs-oxadiaz-bala-betaipr25 2824: phhs-oxadiaz-bala-betaipr
2825: bim-me25thioph-gly-betadcph2825: bim-me25thioph-gly-betadcph
2826: bhs-25oxaz-gly-betameph2826: bras-25oxaz-gly-betameph
2827 : bhs-oxadiaz-gly-betal3bendi2827: bhs-oxadiaz-gly-betal3bendi
2828: ibhis-oxadiaz-gly-zdapee 30 2829: 2py-me24thioph-bala-psdap2828: ibhis-oxadiaz-gly-zdapee 30 2829: 2py-me24thioph-bala-psdap
2830: bhs-25thiaz-bala-betacbph2830: bras-25thiaz-bala-betacbph
2831: 2py-me25oxaz-leu-betadcph2831: 2py-me25oxaz-leu-betadcph
2832 : tolhs-25thiaz-bala-betahcbph2832: tolhs-25thiaz-bala-betahcbph
2833: ibhs-25oxaz-bala-betabdimo 35 2834: 2py-25thioph-ala-betainyl2833: ibhs-25oxaz-bala-betabdimo 35 2834: 2py-25thioph-ala-betainyl
2835: bhs-oxadiaz-bala-betathioph2835: bras-oxadiaz-bala-betathioph
2836: bhs-25methiaz-gly-betaipro2836: bhs-25methiaz-gly-betaipro
2837: bhs-24thioph-ala-betapy2837: bhs-24thioph-ala-betapy
2838: ibhs-25thiaz-gly-betafluo2838: ibhs-25thiaz-gly-betafluo
2839: 2py-24oxaz-gly-zdap2839: 2py-24oxaz-gly-zdap
40 2840: phhs-oxadiaz-bala-betadcphee40 2840: phhs-oxadiaz-bala-betadcphee
2841: 2py-24thiaz-ala-betadcph2841: 2py-24thiaz-ala-betadcph
2842: ibhs-24thiaz-gly-betaheph2842: ibhs-24thiaz-gly-betaheph
2843: bhs-me25oxaz-ala-betapy2843: bhs-me25oxaz-ala-betapy
2844: ibhs-nme35pyr-bala-betaomebendi 45 2845: bhs-thiadiaz-gly-betapy2844: ibhs-nme35pyr-bala-betaomebendi 45 2845: bhs-thiadiaz-gly-betapy
2846: bhs-25thiaz-gly-betadhbfu2846: bhs-25thiaz-gly-betadhbfu
2847: dhim-24oxaz-gly-betapy 2848: gua-24thiaz-gly-betafluo2847: dhim-24oxaz-gly-betapy 2848: gua-24thiaz-gly-betafluo
2849: bhs-thiadiaz-bala-zdap2849: bhs-thiadiaz-bala-zdap
2850: ibhs-25oxaz-gly-betahni2850: ibhs-25oxaz-gly-betahni
2851: tolhs-25thiaz-bala-betahc 5 2852: bhs-nme35pyr-ala-ibsdap2851: tolhs-25thiaz-bala-betahc 5 2852: bhs-nme35pyr-ala-ibsdap
2853: bhs-oxadiaz-gly-betabdimo2853: bhs-oxadiaz-gly-betabdimo
2854: phhs-me24thiaz-leu-betaph2854: phhs-me24thiaz-leu-betaph
2855: tolhs-25thiaz-bala-betathioph2855: tolhs-25thiaz-bala-betathioph
2856: bhs-25oxaz-bala-betatrif2856: bras-25oxaz-bala-betatrif
2857: ibhs-24thiaz-gly-betamesu2857: ibhs-24thiaz-gly-betamesu
10 2858: bim-25thiaz-ala-betainyl10 2858: bim-25thiaz-ala-betainyl
2859: bhs-me25thiaz-leu-zdap2859: bhs-me25thiaz-leu-zdap
2860 : tolhs-me24thiaz-bala-betadcph2860: tolhs-me24thiaz-bala-betadcph
2861: ibhs-25oxaz-gly-betacph2861: ibhs-25oxaz-gly-betacph
2862: bim-26py-ala-zdap 15 2863: bhs-oxadiaz-nmgly-betacph2862: bim-26py-ala-zdap 15 2863: bhs-oxadiaz-nmgly-betacph
2864 : ibhs-25methiaz-gly-beta3quin2864: ibhs-25methiaz-gly-beta3quin
2865: 2py-me25thiaz-gly-zdap2865: 2py-me25thiaz-gly-zdap
2866: 2pmhs-24thioph-bala-betahph2866: 2 pmhs-24thioph-bala-betahph
2867 : impy-25methiaz-bala-betafu3 20 2868: phhs-nme35pyr-gly-betamesu2867: impy-25methiaz-bala-betafu3 20 2868: phhs-nme35pyr-gly-betamesu
2869 : ibhs-oxadiaz-gly-betaphethioa2869: ibhs-oxadiaz-gly-betaphethioa
2870 : tolhs-24thioph-bala-betathioph2870: tolhs-24thioph-bala-betathioph
2871: ibhs-25oxaz-gly-psdaptb2871: ibhs-25oxaz-gly-psdaptb
2872: bim-25methiaz-gly-betapy2872: bim-25methiaz-gly-betapy
2873: 2py-25oxaz-ala-zdap2873: 2py-25oxaz-ala-zdap
25 2874: phhs-24thiaz-gly-betadtrif25 2874: phhs-24thiaz-gly-betadtrif
2875 : bhs-oxadiaz-bala-betacthioph2875: bras-oxadiaz-bala-betacthioph
2876: 2py-nme35pyr-gly-aspbzla2876: 2py-nme35pyr-gly-aspbzla
2877: ibhs-25oxaz-gly-betafu22877: ibhs-25oxaz-gly-betafu2
2878: ibhs-24thioph-bala-betahb 30 2879: bim-me25oxaz-bala-zdap2878: ibhs-24thioph-bala-betahb 30 2879: bim-me25oxaz-bala-zdap
2880 : bim-42nmeim-bala-beta34meoph2880: bim-42nmeim-bala-beta34meoph
2881: bim-me24thiaz-gly-betapy2881: bim-me24thiaz-gly-betapy
2882: phhs-25methiaz-gly-csdap2882: phhs-25methiaz-gly-csdap
2883: bhs-ithiadiaz-gly-betapym 35 2884: phhs-24thioph-bala-betacbph2883: bhs-ithiadiaz-gly-betapym 35 2884: phhs-24thioph-bala-betacbph
2885: bhs-25oxaz-gly-betafu32885: bhs-25oxaz-gly-betafu3
2886: 2py-24im-leu-psdap2886: 2py-24im-leu-psdap
2887: bhs-me25thioph-ala-betadcph2887: bhs-me25thioph-ala-betadcph
2888: tolhs-25thiaz-gly-betadcphee2888: tolhs-25thiaz-gly-betadcphee
2889: bhs-25oxaz-bala-ibsdap2889: bras-25oxaz-bala-ibsdap
40 2890: 2py-me24thiaz-bala-zdap40 2890: 2py-me24thiaz-bala-zdap
2891: bhs-me25thioph-gly-betaph2891: bhs-me25thioph-gly-betaph
2892: phhs-nme35pyr-bala-betaet2892: phhs-nme35pyr-bala-betet
2893: bim-24thiaz-gly-betaanaphth2893: bim-24thiaz-gly-betaanaphth
2894: bhs-24thiaz-ala-betathioph 45 2895: bhs-53pyrazo-leu-zdap2894: bhs-24thiaz-ala-betathioph 45 2895: bhs-53pyrazo-leu-zdap
2896: 2py-42nmeim-bala-betahmph2896: 2py-42nmeim-bala-betahmph
2897: 2py-me25oxaz-gly-betapy 2898: tolhs-24thioph-gly-betamethi2897: 2py-me25oxaz-gly-betapy 2898: tolhs-24thioph-gly-betamethi
2899: bhs-24thioph-bala-betadbph2899: bhs-24thioph-bala-betadbph
2900: ibhs-25thiaz-gly-beta35dbph2900: ibhs-25thiaz-gly-beta35dbph
2901: phhs-24thioph-bala-aspbzla2901: phhs-24thioph-bala-aspbzla
5 2902: tolhs-24thioph-bala-beta35dbph5 2902: tolhs-24thioph-bala-beta35dbph
2903: bhs-nme35pyr-bala-betaipr2903: bhs-nme35pyr-bala-betaipr
2904 : bim-me24thiaz-bala-beta34meoph2904: bim-me24thiaz-bala-beta34meoph
2905: ibhs-24thioph-gly-betamesu2905: ibhs-24thioph-gly-betamesu
2906: 2py-me25thioph-gly-betaph2906: 2py-me25thioph-gly-betaph
2907: dhim-25thioph-ala-psdap 102907: dhim-25thioph-ala-psdap 10
2908: ιmpy-24thιaz-ala-betapy2908: ιmpy-24thιaz-ala-betapy
2909: tolhs-nme35pyr-gly-betahbcph2909: tolhs-nme35pyr-gly-betahbcph
2910: tolhs-oxadiaz-gly-betacthioph2910: tolhs-oxadiaz-gly-betacthioph
2911: bhs-nme35pyr-gly-betahph2911: bhs-nme35pyr-gly-betahph
2912: tolhs-25oxaz-gly-betaipro 15 2913: phhs-25oxaz-bala-betahni2912: tolhs-25oxaz-gly-betaipro 15 2913: phhs-25oxaz-bala-betahni
2914: ibhs-25methiaz-bala-csdap2914: ibhs-25methiaz-bala-csdap
2915: 2py-25thiaz-ala-psdap2915: 2py-25thiaz-ala-psdap
2916: tolhs-me24oxaz-gly-psdap2916: tolhs-me24oxaz-gly-psdap
2917 : ibhs-ithiadiaz-gly-betaftrif 20 2918: phhs-nme35pyr-gly-betadtrif2917: ibhs-ithiadiaz-gly-betaftrif 20 2918: phhs-nme35pyr-gly-betadtrif
2919 : 2pmhs-25methiaz-bala-betal3bendi2919: 2 pmhs-25methiaz-bala-betal3bendi
2920: bhs-oxadiaz-nmgly-beta3 dcph2920: bhs-oxadiaz-nmgly-beta3 dcph
2921: bim-25thiaz-bala-betaipro2921: bim-25thiaz-bala-betaipro
2922 : phhs-oxadiaz-gly-betabthioph2922: phhs-oxadiaz-gly-betabthioph
2923: bhs-24thioph-gly-betahmo2923: bhs-24thioph-gly-betahmo
2924: phhs-24thioph-bala-betahmofu2924: phhs-24thioph-bala-betahmofu
2925: tolhs-me24thiaz-leu-betaph2925: tolhs-me24thiaz-leu-betaph
2926: tolhs-25thiaz-bala-betahbcph2926: tolhs-25thiaz-bala-betahbcph
2927 : ibhs-ithiadiaz-gly-betal3bendi2927: ibhs-ithiadiaz-gly-betal3bendi
2928: tolhs-ithiadiaz-gly-suabu 30 2929: bim-26py-ala-betapy2928: tolhs-ithiadiaz-gly-suabu 30 2929: bim-26py-ala-betapy
2930 : ibhs-24thioph-bala-betacthioph2930: ibhs-24thioph-bala-betacthioph
2931: ibhs-25thiaz-gly-betaet2931: ibhs-25thiaz-gly-betaet
2932: phhs-nme35pyr-gly-betaoxope2932: phhs-nme35pyr-gly-betaoxope
2933: bim-35fur-gly-betapy 35 2934: phhs-oxadiaz-gly-betafu22933: bim-35fur-gly-betapy 35 2934: phhs-oxadiaz-gly-betafu2
2935: bhs-52thiaz-ala-betadcph2935: bhs-52thiaz-ala-betadcph
2936: tolhs-25methiaz-bala-betahmph2936: tolhs-25methiaz-bala-betahmph
2937 : ibhs-25thiaz-bala-betaftrif2937: ibhs-25thiaz-bala-betaftrif
2938: tolhs-oxadiaz-bala-zdap2938: tolhs-oxadiaz-bala-zdap
2939 : bim-me25thioph-ala-beta34meoph2939: bim-me25thioph-ala-beta34meoph
40 2940: gua-42pym-gly-beta35dbph40 2940: gua-42pym-gly-beta35dbph
2941: gua-26py-gly-betabpy2941: gua-26py-gly-betabpy
2942: 4pmhs-25thiaz-gly-zdap2942: 4 pmhs-25thiaz-gly-zdap
2943 : tolhs-oxadiaz-gly-betaphethioa2943: tolhs-oxadiaz-gly-betaphethioa
2944 : tolhs-nme35pyr-gly-betatbuph 45 2945: gua-26py-gly-betahbcph2944: tolhs-nme35pyr-gly-betatbuph 45 2945: gua-26py-gly-betahbcph
2946 : bhs-25thiaz-bala-betacthioph2946: bhs-25thiaz-bala-betacthioph
2947: ibhs-24thioph-bala-suabu 2948: ibhs-24thiaz-gly-betacph2947: ibhs-24thioph-bala-suabu 2948: ibhs-24thiaz-gly-betacph
2949: ibhs-nme35pyr-gly-betaftrif2949: ibhs-nme35pyr-gly-betaftrif
2950: 2py-me25thiaz-gly-betadcph2950: 2py-me25thiaz-gly-betadcph
2951: 2py-24oxaz-ala-zdap2951: 2py-24oxaz-ala-zdap
5 2952: agua-24thiaz-gly-betadcph5 2952: agua-24thiaz-gly-betadcph
2953: impy-42nmeim-bala-betahb2953: impy-42nmeim-bala-betahb
2954: bhs-25oxaz-bala-betabdimo2954: bras-25oxaz-bala-betabdimo
2955: phhs-nme35pyr-bala-zdap2955: phhs-nme35pyr-bala-zdap
2956: bhs-me24thiaz-leu-zdap2956: bhs-me24thiaz-leu-zdap
2957 : tolhs-24thiaz-bala-beta23meoph 10 2958: bhs-triaz-gly-betameph2957: tolhs-24thiaz-bala-beta23meoph 10 2958: bhs-triaz-gly-betameph
2959 : bhs-ithiadiaz-gly-betathio32959: bhs-ithiadiaz-gly-betathio3
2960: ibhs-nme35pyr-bala-betafph2960: ibhs-nme35pyr-bala-betafph
2961: gua-24thiaz-gly-betahni2961: gua-24thiaz-gly-betahni
2962 : bhs-25thiaz-nmgly-betacthioph 15 2963: tolhs-25oxaz-bala-betadcphch2962: bhs-25thiaz-nmgly-betacthioph 15 2963: tolhs-25oxaz-bala-betadcphch
2964: phhs-25thiaz-bala-betafu32964: phhs-25thiaz-bala-betafu3
2965 : tolhs-ithiadiaz-bala-zdaptb2965: tolhs-ithiadiaz-bala-zdaptb
2966 : ibhs-ithiadiaz-gly-betaipro2966: ibhs-ithiadiaz-gly-betaipro
2967: bhs-25oxaz-ala-betaoxaz 20 2968: phhs-ithiadiaz-gly-betaipr2967: bhs-25oxaz-ala-betaoxaz 20 2968: phhs-ithiadiaz-gly-betaipr
2969: bhs-nme35pyr-bala-betabenfu2969: bhs-nme35pyr-bala-betabenfu
2970: 2py-52thiaz-ala-psdap2970: 2py-52thiaz-ala-psdap
2971: bhs-24thioph-gly-betabpy2971: bhs-24thioph-gly-betabpy
2972 : dhthi-25methiaz-bala-betadcph2972: dhthi-25methiaz-bala-betadcph
2973 : ibhs-24thioph-gly-betaomebendi 25 2974 : tolhs-nme35pyr-gly-betadcphch2973: ibhs-24thioph-gly-betaomebendi 25 2974: tolhs-nme35pyr-gly-betadcphch
2975: bhs-25thiaz-bala-betaanaphth2975: bhs-25thiaz-bala-betaanaphth
2976: bhs-25methiaz-ala-betaoxaz2976: bhs-25methiaz-ala-betaoxaz
2977 : tolhs-25methiaz-bala-betadmph2977: tolhs-25methiaz-bala-betadmph
2978: 2py-42nmeim-gly-betadcph 30 2979: bhs-35thioph-gly-betadcph2978: 2py-42nmeim-gly-betadcph 30 2979: bhs-35thioph-gly-betadcph
2980: phhs-nme35pyr-bala-betahmofu2980: phhs-nme35pyr-bala-betahmofu
2981: ibhs-25methiaz-gly-betahmph2981: ibhs-25methiaz-gly-betahmph
2982: tolhs-ithiadiaz-gly-betapym2982: tolhs-ithiadiaz-gly-betapym
2983 : bhs-ithiadiaz-gly-betadcphee 35 2984: bim-53pyrazo-bala-betadcph2983: bhs-ithiadiaz-gly-betadcphee 35 2984: bim-53pyrazo-bala-betadcph
2985: tolhs-25oxaz-bala-betabph2985: tolhs-25oxaz-bala-betabph
2986: ibhs-25oxaz-gly-betahph2986: ibhs-25oxaz-gly-betahph
2987: tolhs-25oxaz-gly-betampy2987: tolhs-25oxaz-gly-betampy
2988: ibhs-oxadiaz-bala-zdaptb2988: ibhs-oxadiaz-bala-zdaptb
2989: bhs-oxadiaz-bala-betafbph2989: bras-oxadiaz-bala-betafbph
2990: tolhs-25oxaz-gly-betaipr2990: tolhs-25oxaz-gly-betaipr
2991 : bim-me24thioph-bala-beta34meoph2991: bim-me24thioph-bala-beta34meoph
2992: bhs-42pym-gly-betadcph2992: bhs-42pym-gly-betadcph
2993 : phhs-25methiaz-bala-betadtrif2993: phhs-25methiaz-bala-betadtrif
2994: 2py-25oxaz-gly-betaipr 45 2995: phhs-oxadiaz-bala-betacbph2994: 2py-25oxaz-gly-betaipr 45 2995: phhs-oxadiaz-bala-betacbph
2996: ibhs-24thioph-gly-betaoxaz2996: ibhs-24thioph-gly-betaoxaz
2997 : tolhs-ithiadiaz-gly-betaftrif 2998: bhs-nme35pyr-nmgly-betaoxaz2997: tolhs-ithiadiaz-gly-betaftrif 2998: bhs-nme35pyr-nmgly-betaoxaz
2999: bhs-25thiaz-ala-betabnaphth2999: bhs-25thiaz-ala-betabnaphth
3000: phhs-24thioph-gly-betacbph3000: phhs-24thioph-gly-betacbph
3001: bhs-me25thioph-leu-betapy 5 3002: bhs-me24thiaz-ala-betadcph3001: bhs-me25thioph-leu-betapy 5 3002: bhs-me24thiaz-ala-betadcph
3003: ibhs-25thiaz-bala-betaol3003: ibhs-25thiaz-bala-betaol
3004: ibhs-25methiaz-gly-betabediox3004: ibhs-25methiaz-gly-betabediox
3005: phhs-25thiaz-gly-betaipr3005: phhs-25thiaz-gly-betaipr
3006: bim-24oxaz-bala-zdap3006: bim-24oxaz-bala-zdap
3007: bhs-25oxaz-bala-zdapch3007: bras-25oxaz-bala-zdapch
1010
3008: 3pmhs-25thiaz-bala-betapy3008: 3 pmhs-25thiaz-bala-betapy
3009: tolhs-25methiaz-bala-betafluo3009: tolhs-25methiaz-bala-betafluo
3010 : bhs-ithiadiaz-gly-betapbiph3010: bhs-ithiadiaz-gly-betapbiph
3011: phhs-24thiaz-gly-beta23meoph3011: phhs-24thiaz-gly-beta23meoph
3012: bhs-nme35pyr-gly-betadhbfu 15 3013: ibhs-25oxaz-bala-aspaba3012: bhs-nme35pyr-gly-betadhbfu 15 3013: ibhs-25oxaz-bala-aspaba
3014: thpym-24thiaz-gly-betadcph3014: thpym-24thiaz-gly-betadcph
3015: bhs-oxadiaz-gly-betafbph3015: bhs-oxadiaz-gly-betafbph
3016: 2py-25thiaz-leu-psdap3016: 2py-25thiaz-leu-psdap
3017: 2py-53pyrazo-ala-psdap 20 3018: ibhs-nme35pyr-bala-beta23meoph3017: 2py-53pyrazo-ala-psdap 20 3018: ibhs-nme35pyr-bala-beta23meoph
3019: tolhs-24thioph-gly-betahni3019: tolhs-24thioph-gly-betahni
3020 : ibhs-24thioph-gly-betamethioph3020: ibhs-24thioph-gly-betamethioph
3021: bhs-25methiaz-bala-betahc3021: bras-25methiaz-bala-betahc
3022 : phhs-oxadiaz-bala-betamethioph3022: phhs-oxadiaz-bala-betamethioph
3023: ibhs-25methiaz-bala-aspaba3023: ibhs-25methiaz-bala-aspaba
2525
3024 : bim-24thioph-gly-betaomebendi3024: bim-24thioph-gly-betaomebendi
3025: tolhs-ithiadiaz-gly-betapytb3025: tolhs-ithiadiaz-gly-betapytb
3026: bim-25methiaz-gly-betatrif3026: bim-25methiaz-gly-betatrif
3027: 2py-me25thiaz-gly-betaph3027: 2py-me25thiaz-gly-betaph
3028: phhs-25oxaz-bala-betabpy 30 3029: phhs-nme35pyr-gly-betahph3028: phhs-25oxaz-bala-betabpy 30 3029: phhs-nme35pyr-gly-betahph
3030: tolhs-ithiadiaz-gly-betabmph3030: tolhs-ithiadiaz-gly-betabmph
3031: tolhs-25methiaz-gly-betahni3031: tolhs-25methiaz-gly-betahni
3032 : phhs-25methiaz-bala-betaomebendi3032: phhs-25methiaz-bala-betaomebendi
3033: tolhs-oxadiaz-gly-betamethi 35 3034: ibhs-24thiaz-bala-csdap3033: tolhs-oxadiaz-gly-betamethi 35 3034: ibhs-24thiaz-bala-csdap
3035: ibhs-ithiadiaz-gly-betaomebendi3035: ibhs-ithiadiaz-gly-betaomebendi
3036: tolhs-oxadiaz-bala-betamesu3036: tolhs-oxadiaz-bala-betamesu
3037: bhs-24thioph-gly-psdapch3037: bhs-24thioph-gly-psdapch
3038: phhs-24thioph-gly-zdap3038: phhs-24thioph-gly-zdap
3039: 2py-25oxaz-bala-psdap3039: 2py-25oxaz-bala-psdap
40 3040: bhs-me24thiaz-ala-betapy40 3040: bhs-me24thiaz-ala-betapy
3041 : tolhs-24thioph-bala-beta34dcph3041: tolhs-24thioph-bala-beta34dcph
3042: 2py-25thioph-leu-betadcph3042: 2py-25thioph-leu-betadcph
3043: bhs-25methiaz-gly-betafluo3043: bhs-25methiaz-gly-betafluo
3044: tolhs-25oxaz-gly-betahmph 45 3045: tolhs-nme35pyr-bala-betacbph3044: tolhs-25oxaz-gly-betahmph 45 3045: tolhs-nme35pyr-bala-betacbph
3046: ibhs-25thiaz-bala-betahni3046: ibhs-25thiaz-bala-betahni
3047: sabhs-25methiaz-gly-psdap 3048: ibhs-ithiadiaz-gly-zdapee3047: sabhs-25methiaz-gly-psdap 3048: ibhs-ithiadiaz-gly-zdapee
3049: ibhs-nme35pyr-gly-betafph3049: ibhs-nme35pyr-gly-betafph
3050: bim-25thioph-bala-betadcph3050: bim-25thioph-bala-betadcph
3051: phhs-25oxaz-bala-betahph 5 3052: phhs-nme35pyr-bala-aspaba3051: phhs-25oxaz-bala-betahph 5 3052: phhs-nme35pyr-bala-aspaba
3053: ibhs-24thioph-gly-beta4bph3053: ibhs-24thioph-gly-beta4bph
3054: bhs-25thiaz-gly-betatrif3054: bhs-25thiaz-gly-betatrif
3055: bhs-25thiaz-bala-betathio33055: bhs-25thiaz-bala-betathio3
3056: tolhs-ithiadiaz-gly-betathio33056: tolhs-ithiadiaz-gly-betathio3
3057: tolhs-ithiadiaz-bala-zdap3057: tolhs-ithiadiaz-bala-zdap
10 3058: bim-24thiaz-bala-betatos10 3058: bim-24thiaz-bala-betatos
3059: tolhs-25oxaz-gly-suabu3059: tolhs-25oxaz-gly-suabu
3060 : bhs-24thioph-bala-betapbiph3060: bhs-24thioph-bala-betapbiph
3061: ibhs-oxadiaz-bala-betabnaphth3061: ibhs-oxadiaz-bala-betabnaphth
3062: bim-42nmeim-gly-zdap 15 3063: phhs-me25thiaz-leu-betapy3062: bim-42nmeim-gly-zdap 15 3063: phhs-me25thiaz-leu-betapy
3064: bhs-25methiaz-gly-betamesu3064: bhs-25methiaz-gly-betamesu
3065: bhs-me25thiaz-gly-psdap3065: bhs-me25thiaz-gly-psdap
3066: tolhs-me25oxaz-bala-zdap3066: tolhs-me25oxaz-bala-zdap
3067: bim-53pyrazo-ala-betapy 20 3068: phhs-ithiadiaz-bala-beta34dcph3067: bim-53pyrazo-ala-betapy 20 3068: phhs-ithiadiaz-bala-beta34dcph
3069: ibhs-25thiaz-gly-betapyee3069: ibhs-25thiaz-gly-betapyee
3070: tolhs-25thiaz-bala-betaoxope3070: tolhs-25thiaz-bala-betaoxope
3071: ibhs-25methiaz-gly-betampy3071: ibhs-25methiaz-gly-betampy
3072 : tolhs-24thiaz-gly-betaoxope3072: tolhs-24thiaz-gly-betaoxope
3073 : bhs-oxadiaz-gly-beta34meoph3073: bhs-oxadiaz-gly-beta34meoph
25 3074: tolhs-ithiadiaz-bala-betaoxaz25 3074: tolhs-ithiadiaz-bala-betaoxaz
3075 : phhs-24thioph-gly-betadcphch3075: phhs-24thioph-gly-betadcphch
3076: 2py-me24thiaz-bala-psdap3076: 2py-me24thiaz-bala-psdap
3077: bhs-25thiaz-ala-betainyl3077: bhs-25thiaz-ala-betainyl
3078: phhs-25thiaz-gly-betahdcph 30 3079: phhs-25thiaz-gly-betah35dc3078: phhs-25thiaz-gly-betahdcph 30 3079: phhs-25thiaz-gly-betahdcph
3080: tolhs-25methiaz-gly-betathio33080: tolhs-25methiaz-gly-betathio3
3081: 2py-me24thioph-gly-betaph3081: 2py-me24thioph-gly-betaph
3082 : bhs-24thioph-bala-betaoxope3082: bhs-24thioph-bala-betaoxope
3083: bhs-24thiaz-bala-aspbzla 35 3084: phhs-25thiaz-bala-betamethioph3083: bhs-24thiaz-bala-aspbzla 35 3084: phhs-25thiaz-bala-betamethioph
3085: tolhs-25thiaz-bala-betadcphee3085: tolhs-25thiaz-bala-betadcphee
3086: bhs-24thioph-leu-betadcph3086: bhs-24thioph-leu-betadcph
3087: ibhs-24thioph-gly-ibsdap3087: ibhs-24thioph-gly-ibsdap
3088: phhs-nme35pyr-gly-betaibph3088: phhs-nme35pyr-gly-betaibph
3089: phhs-25thiaz-bala-betahdbph3089: phhs-25thiaz-bala-betahdbph
40 3090: bgua-24thiaz-gly-psdap40 3090: bgua-24thiaz-gly-psdap
3091: bhs-25oxaz-gly-betadcph3091: bhs-25oxaz-gly-betadcph
3092: phhs-nme35pyr-bala-betaol3092: phhs-nme35pyr-bala-betaol
3093 : tolhs-ithiadiaz-bala-betaibph3093: tolhs-ithiadiaz-bala-betaibph
3094: phhs-25thiaz-bala-betacph 45 3095: ibhs-nme35pyr-bala-betabediox3094: phhs-25thiaz-bala-betacph 45 3095: ibhs-nme35pyr-bala-betabediox
3096 : tolhs-ithiadiaz-gly-betapych3096: tolhs-ithiadiaz-gly-betapych
3097: bhs-nme35pyr-gly-psdap 3098: phhs-25thiaz-gly-betahb3097: bhs-nme35pyr-gly-psdap 3098: phhs-25thiaz-gly-betahb
3099: phhs-24thiaz-gly-betafu23099: phhs-24thiaz-gly-betafu2
3100 : tolhs-ithiadiaz-bala-betadcph3100: tolhs-ithiadiaz-bala-betadcph
3101: ibhs-25oxaz-gly-betabph 5 3102: gua-24oxaz-gly-betapym3101: ibhs-25oxaz-gly-betabph 5 3102: gua-24oxaz-gly-betapym
3103 : tolhs-25thiaz-bala-betabediox3103: tolhs-25thiaz-bala-betabediox
3104: bim-thiadiaz-bala-psdap3104: bim-thiadiaz-bala-psdap
3105 : tolhs-24thiaz-bala-betamethi3105: tolhs-24thiaz-bala-betamethi
3106: bhs-24thioph-gly-betaol3106: bhs-24thioph-gly-betaol
3107: bim-25thioph-bala-psdap3107: bim-25thioph-bala-psdap
1010
3108: tolhs-25oxaz-gly-aspbzla3108: tolhs-25oxaz-gly-aspbzla
3109 : tolhs-24thioph-bala-betaamibe3109: tolhs-24thioph-bala-betaamibe
3110: bhs-me24thiaz-gly-betapy3110: bhs-me24thiaz-gly-betapy
3111: ibhs-oxadiaz-bala-betadmoph3111: ibhs-oxadiaz-bala-betadmoph
3112: tolhs-25thiaz-bala-betabmph 15 3113: phhs-25thiaz-bala-betabmph3112: tolhs-25thiaz-bala-betabmph 15 3113: phhs-25thiaz-bala-betabmph
3114 : phhs-25oxaz-bala-beta34meoph3114: phhs-25oxaz-bala-beta34meoph
3115: phhs-25methiaz-gly-asppha3115: phhs-25methiaz-gly-asppha
3116: bhs-25methiaz-bala-betatrif3116: bras-25methiaz-bala-betatrif
3117: bim-me24thiaz-leu-psdap 20 3118: ibhs-25thiaz-gly-betabdimo3117: bim-me24thiaz-leu-psdap 20 3118: ibhs-25thiaz-gly-betabdimo
3119: gua-25oxaz-gly-zdap3119: gua-25oxaz-gly-zdap
3120: bhs-25oxaz-gly-betahmph3120: bhs-25oxaz-gly-betahmph
3121: bim-42pym-gly-betapy3121: bim-42pym-gly-betapy
3122: ibhs-25thiaz-gly-psdaptb3122: ibhs-25thiaz-gly-psdaptb
3123: bhs-25oxaz-bala-beta4bph3123: bhs-25oxaz-bala-beta4bph
25 3124 : bhs-ithiadiaz-gly-betahcbph25 3124: bhs-ithiadiaz-gly-betahcbph
3125: ibhs-25thiaz-bala-zdapch3125: ibhs-25thiaz-bala-zdapch
3126: ibhs-nme35pyr-bala-busu2be3126: ibhs-nme35pyr-bala-busu2be
3127: bhs-24oxaz-ala-betadcph3127: bras-24oxaz-ala-betadcph
3128: bhs-25methiaz-gly-betapyee 30 3129: ibhs-24thiaz-bala-betabph3128: bhs-25methiaz-gly-betapyee 30 3129: ibhs-24thiaz-bala-betabph
3130 : phhs-ithiadiaz-bala-betabnaphth3130: phhs-ithiadiaz-bala-betabnaphth
3131: ibhs-ithiadiaz-bala-zdapch3131: ibhs-ithiadiaz-bala-zdapch
3132: bhs-nme35pyr-nmgly-betaipro3132: bhs-nme35pyr-nmgly-betaipro
3133: bhs-25thiaz-bala-csdap3133: bhs-25thiaz-bala-csdap
35 3134: tolhs-ithiadiaz-bala-betathiobe35 3134: tolhs-ithiadiaz-bala-betathiobe
3135: bhs-24thiaz-gly-betadcph3135: bhs-24thiaz-gly-betadcph
3136: dhim-25thiaz-gly-betadcph3136: dhim-25thiaz-gly-betadcph
3137: tolhs-25oxaz-bala-betatrif3137: tolhs-25oxaz-bala-betatrif
3138: impy-24thioph-ala-betapy3138: impy-24thioph-ala-betapy
3139: phhs-25methiaz-gly-betathio33139: phhs-25methiaz-gly-betathio3
40 3140: gua-24thiaz-gly-betapyr40 3140: gua-24thiaz-gly-betapyr
3141 : impy-24thiaz-bala-betaftrif3141: impy-24thiaz-bala-betaftrif
3142: phhs-nme35pyr-bala-betahni3142: phhs-nme35pyr-bala-betahni
3143: 2py-42nmeim-bala-psdap3143: 2py-42nmeim-bala-psdap
3144: ibhs-25thiaz-bala-asppha 45 3145: phhs-24thioph-bala-psdapch3144: ibhs-25thiaz-bala-asppha 45 3145: phhs-24thioph-bala-psdapch
3146: tolhs-24thiaz-gly-betadmph3146: tolhs-24thiaz-gly-betadmph
3147: bim-24thiaz-gly-betadbph 3148: bhs-42pym-gly-betapy3147: bim-24thiaz-gly-betadbph 3148: bhs-42pym-gly-betapy
3149: phhs-25methiaz-bala-betafluo3149: phhs-25methiaz-bala-betafluo
3150: 2py-35thioph-ala-zdap3150: 2py-35thioph-ala-zdap
3151: tolhs-24thiaz-bala-betaoxaz 5 3152: phhs-24thioph-bala-betatos3151: tolhs-24thiaz-bala-betaoxaz 5 3152: phhs-24thioph-bala-betatos
3153 : tolhs-oxadiaz-bala-beta23meoph3153: tolhs-oxadiaz-bala-beta23meoph
3154: bhs-ithiadiaz-nmgly-betabpy3154: bhs-ithiadiaz-nmgly-betabpy
3155: tolhs-nme35pyr-bala-betameph3155: tolhs-nme35pyr-bala-betameph
3156: tolhs-ithiadiaz-gly-betacph3156: tolhs-ithiadiaz-gly-betacph
3157: bhs-24oxaz-ala-betapy3157: bras-24oxaz-ala-betapy
3158: 2py-24thioph-bala-zdap3158: 2py-24thioph-bala-zdap
3159: bim-25thiaz-bala-betahcbph3159: bim-25thiaz-bala-betahcbph
3160: phhs-25thiaz-gly-betathiobe3160: phhs-25thiaz-gly-betathiobe
3161: bhs-24thioph-bala-busu2be3161: bhs-24thioph-bala-busu2be
3162: phhs-me25oxaz-bala-psdap 15 3163: phhs-25thiaz-gly-betatos3162: phhs-me25oxaz-bala-psdap 15 3163: phhs-25thiaz-gly-betatos
3164 : bhs-25thiaz-nmgly-betabnaphth3164: bhs-25thiaz-nmgly-betabnaphth
3165: tolhs-24thioph-gly-betadcphtb3165: tolhs-24thioph-gly-betadcphtb
3166: ibhs-ithiadiaz-gly-betacph3166: ibhs-ithiadiaz-gly-betacph
3167 : phhs-ithiadiaz-bala-betahph 20 3168: ibhs-ithiadiaz-bala-betaet3167: phhs-ithiadiaz-bala-betahph 20 3168: ibhs-ithiadiaz-bala-betet
3169: phhs-25methiaz-bala-ibsdap3169: phhs-25methiaz-bala-ibsdap
3170: tolhs-25methiaz-gly-betahdcph3170: tolhs-25methiaz-gly-betahdcph
3171: ibhs-25oxaz-bala-betahmofu3171: ibhs-25oxaz-bala-betahmofu
3172: bhs-24thioph-gly-betahmofu3172: bhs-24thioph-gly-betahmofu
3173: 2py-me25oxaz-ba1a-betadcph3173: 2py-me25oxaz-ba1a-betadcph
3174 : bhs-nme35pyr-bala-betacthioph3174: bhs-nme35pyr-bala-betacthioph
3175: ibhs-24thioph-bala-betaipro3175: ibhs-24thioph-bala-betaipro
3176: bim-25methiaz-gly-betahmph3176: bim-25methiaz-gly-betahmph
3177: sabhs-26py-gly-betainyl3177: sabhs-26py-gly-betainyl
3178: phhs-ithiadiaz-gly-psdapch 30 3179: bim-me25oxaz-bala-betaph3178: phhs-ithiadiaz-gly-psdapch 30 3179: bim-me25oxaz-bala-betaph
3180 : phhs-oxadiaz-bala-betaphethioa3180: phhs-oxadiaz-bala-betaphethioa
3181 : tolhs-ithiadiaz-bala-betainyl3181: tolhs-ithiadiaz-bala-betainyl
3182: bhs-24thioph-nmgly-betadhbfu3182: bhs-24thioph-nmgly-betadhbfu
3183: phhs-25methiaz-gly-betaol 35 3184: phhs-ithiadiaz-bala-betabph3183: phhs-25methiaz-gly-betaol 35 3184: phhs-ithiadiaz-bala-betabph
3185: 2py-me25thioph-ala-zdap3185: 2py-me25thioph-ala-zdap
3186: bim-ithiadiaz-bala-aspaba3186: bim-ithiadiaz-bala-aspaba
3187: dhim-26py-nmgly-zdap3187: dhim-26py-nmgly-zdap
3188: 2py-24thioph-ala-betapy3188: 2py-24thioph-ala-betapy
3189: tolhs-25oxaz-gly-betafu3 403189: tolhs-25oxaz-gly-betafu3 40
3190: tolhs-25oxaz-bala-betahdcph3190: tolhs-25oxaz-bala-betahdcph
3191 : bhs-ithiadiaz-gly-betatbuph3191: bhs-ithiadiaz-gly-betatbuph
3192: 2py-25methiaz-bala-betahni3192: 2py-25methiaz-bala-betahni
3193: bhs-24thiaz-ala-betaipro3193: bhs-24thiaz-ala-betaipro
3194: bhs-24thiaz-gly-aspaba3194: bhs-24thiaz-gly-aspaba
45 3195: ibhs-nme35pyr-bala-aspibua45 3195: ibhs-nme35pyr-bala-aspibua
3196: bhs-25methiaz-bala-betabmph3196: bras-25methiaz-bala-betabmph
3197: bhs-25methiaz-ala-betamesu 3198: bhs-nme35pyr-bala-betadcph3197: bhs-25methiaz-ala-betamesu 3198: bhs-nme35pyr-bala-betadcph
3199: impy-42nmeim-bala-betapy3199: impy-42nmeim-bala-betapy
3200: ibhs-25methiaz-bala-betadbph3200: ibhs-25methiaz-bala-betadbph
3201: ibhs-ithiadiaz-bala-asppha 5 3202: tolhs-25methiaz-bala-betatrif3201: ibhs-ithiadiaz-bala-asppha 5 3202: tolhs-25methiaz-bala-betatrif
3203: ibhs-ithiadiaz-bala-betapym3203: ibhs-ithiadiaz-bala-betapym
3204 : bhs-nme35pyr-nmgly-betathioph3204: bhs-nme35pyr-nmgly-betathioph
3205: tolhs-me25oxaz-bala-psdap3205: tolhs-me25oxaz-bala-psdap
3206: tolhs-24thioph-bala-betatbuph3206: tolhs-24thioph-bala-betatbuph
3207: bhs-ithiadiaz-bala-busu2be3207: bhs-ithiadiaz-bala-busu2be
3208: tolhs-oxadiaz-bala-aspibua3208: tolhs-oxadiaz-bala-aspibua
3209: phhs-ithiadiaz-gly-betafphe3209: phhs-ithiadiaz-gly-betafphe
3210 : ibhs-25methiaz-gly-betahdbph3210: ibhs-25methiaz-gly-betahdbph
3211: bhs-me24oxaz-gly-psdap3211: bhs-me24oxaz-gly-psdap
3212: bhs-46pym-ala-zdap 15 3213: bim-25thioph-ala-betainyl3212: bhs-46pym-ala-zdap 15 3213: bim-25thioph-ala-betainyl
3214: phhs-24thioph-gly-betampy3214: phhs-24thioph-gly-betampy
3215: gua-26py-gly-betaftrif3215: gua-26py-gly-betaftrif
3216: ibhs-25thiaz-bala-betabmph3216: ibhs-25thiaz-bala-betabmph
3217: ibhs-oxadiaz-gly-betadcph 20 3218: 2pmhs-25methiaz-bala-betabmph3217: ibhs-oxadiaz-gly-betadcph 20 3218: 2 pmhs-25methiaz-bala-betabmph
3219: bim-ithiadiaz-gly-asppha3219: bim-ithiadiaz-gly-asppha
3220 : phhs-25methiaz-gly-beta34dcph3220: phhs-25methiaz-gly-beta34dcph
3221 : tolhs-24thioph-gly-betahcbph3221: tolhs-24thioph-gly-betahcbph
3222 : bhs-ithiadiaz-nmgly-betafphe3222: bhs-ithiadiaz-nmgly-betafphe
3223 : ibhs-ithiadiaz-gly-betaphethio 25 3224: phhs-25oxaz-bala-zdapch3223: ibhs-ithiadiaz-gly-betaphethio 25 3224: phhs-25oxaz-bala-zdapch
3225: ibhs-oxadiaz-gly-betamesu3225: ibhs-oxadiaz-gly-betamesu
3226 : tolhs-oxadiaz-bala-betadcphee3226: tolhs-oxadiaz-bala-betadcphee
3227: tolhs-ithiadiaz-gly-aspaba3227: tolhs-ithiadiaz-gly-aspaba
3228: impy-24thioph-bala-busu2be3228: impy-24thioph-bala-busu2be
30 3229: bhs-24thioph-leu-zdap30 3229: bhs-24thioph-leu-zdap
3230 : ibhs-oxadiaz-bala-betaftrif3230: ibhs-oxadiaz-bala-betaftrif
3231: gua-26py-gly-betapbiph3231: gua-26py-gly-betapbiph
3232: ibhs-oxadiaz-gly-betapytb3232: ibhs-oxadiaz-gly-betapytb
3233: bim-25fur-gly-betadcph3233: bim-25fur-gly-betadcph
35 3234: bhs-24thiaz-gly-psdaptb35 3234: bhs-24thiaz-gly-psdaptb
3235: ibhs-ithiadiaz-gly-beta34meoph3235: ibhs-ithiadiaz-gly-beta34meoph
3236 : tolhs-25thiaz-bala-betadcphch3236: tolhs-25thiaz-bala-betadcphch
3237: phhs-24thioph-bala-betahb3237: phhs-24thioph-bala-betahb
3238: 2py-25thiaz-gly-psdap3238: 2py-25thiaz-gly-psdap
3239: tolhs-24thiaz-gly-betahdbph 40 3240: ιbhs-nme35pyr-gly-psdap3239: tolhs-24thiaz-gly-betahdbph 40 3240: ιbhs-nme35pyr-gly-psdap
3241: bhs-25thiaz-leu-betameph3241: bhs-25thiaz-leu-betameph
3242: bhs-25thiaz-bala-betafphe3242: bras-25thiaz-bala-betafphe
3243 : ibhs-oxadiaz-gly-beta34meoph3243: ibhs-oxadiaz-gly-beta34meoph
3244: phhs-me24oxaz-ala-zdap3244: phhs-me24oxaz-ala-zdap
45 3245: ibhs-ithiadiaz-gly-betabpy45 3245: ibhs-ithiadiaz-gly-betabpy
3246: bhs-ithiadiaz-gly-betamethi3246: bhs-ithiadiaz-gly-betamethi
3247: phhs-25thiaz-bala-csdap 3248: bhs-25thiaz-met-betadcph3247: phhs-25thiaz-bala-csdap 3248: bhs-25thiaz-met-betadcph
3249 : 2py-nme35pyr-bala-psdap3249: 2py-nme35pyr-bala-psdap
3250: bhs-25thiaz-gly-betatos3250: bhs-25thiaz-gly-betatos
3251: bhs-25oxaz-gly-betaomebendi 5 3252: bhs-24thiaz-gly-betapyee3251: bhs-25oxaz-gly-betaomebendi 5 3252: bhs-24thiaz-gly-betapyee
3253: ibhs-oxadiaz-bala-betafphe3253: ibhs-oxadiaz-bala-betafphe
3254: gua-24thiaz-nmgly-betapy3254: gua-24thiaz-nmgly-betapy
3255: ibhs-24thiaz-bala-psdapee3255: ibhs-24thiaz-bala-psdapee
3256: 2py-25methiaz-bala-aspaba3256: 2py-25methiaz-bala-aspaba
3257: ibhs-25thiaz-gly-betabediox3257: ibhs-25thiaz-gly-betabediox
3258: phhs-me24thiaz-leu-beta34meoph3258: phhs-me24thiaz-leu-beta34meoph
3259 : ibhs-25methiaz-bala-betabthioph3259: ibhs-25methiaz-bala-betabthioph
3260: ibhs-25oxaz-gly-betapych3260: ibhs-25oxaz-gly-betapych
3261: 2py-52thiaz-ala-betainyl3261: 2py-52thiaz-ala-betainyl
3262: tolhs-me24thioph-ala-zdap 15 3263: ibhs-24thioph-gly-betabmph3262: tolhs-me24thioph-ala-zdap 15 3263: ibhs-24thioph-gly-betabmph
3264: bhs-25thiaz-gly-zdaptb3264: bhs-25thiaz-gly-zdaptb
3265: phhs-24thioph-bala-ibsdap3265: phhs-24thioph-bala-ibsdap
3266: bhs-nme35pyr-gly-betahni3266: bhs-nme35pyr-gly-betahni
3267: bhs-25oxaz-gly-zdapch 20 3268: phhs-25oxaz-gly-betafu33267: bhs-25oxaz-gly-zdapch 20 3268: phhs-25oxaz-gly-betafu3
3269: phhs-25thiaz-bala-betadmoph3269: phhs-25thiaz-bala-betadmoph
3270: bhs-oxadiaz-nmgly-betadmoph3270: bhs-oxadiaz-nmgly-betadmoph
3271: bhs-25methiaz-gly-betahbcph3271: bhs-25methiaz-gly-betahbcph
3272 : tolhs-25methiaz-bala-betabthioph3272: tolhs-25methiaz-bala-betabthioph
3273: bhs-oxadiaz-bala-zdapch 25 3274: gua-24oxaz-gly-betaamι.be3273: bras-oxadiaz-bala-zdapch 25 3274: gua-24oxaz-gly-betaamι.be
3275: phhs-25thiaz-gly-betabpy3275: phhs-25thiaz-gly-betabpy
3276: bhs-24im-bala-psdap3276: bras-24im-bala-psdap
3277: phhs-24thiaz-bala-asppha3277: phhs-24thiaz-bala-asppha
3278 : ibhs-ithiadiaz-gly-betadmoph 30 3279: tolhs-24thioph-bala-suabu3278: ibhs-ithiadiaz-gly-betadmoph 30 3279: tolhs-24thioph-bala-suabu
3280: bim-me24oxaz-bala-betadcph3280: bim-me24oxaz-bala-betadcph
3281: tolhs-oxadiaz-bala-betabph3281: tolhs-oxadiaz-bala-betabph
3282: phhs-24thiaz-bala-betaipro3282: phhs-24thiaz-bala-betaipro
3283: bhs-oxadiaz-bala-betaipro 35 3284: phhs-25oxaz-bala-betadtrif3283: bhs-oxadiaz-bala-betaipro 35 3284: phhs-25oxaz-bala-betadtrif
3285: ibhs-25oxaz-gly-betambiph3285: ibhs-25oxaz-gly-betambiph
3286: bhs-nme35pyr-gly-aspibua3286: bhs-nme35pyr-gly-aspibua
3287: bim-oxadiaz-leu-betapy3287: bim-oxadiaz-leu-betapy
3288: bhs-oxadiaz-ala-betaanaphth3288: bhs-oxadiaz-ala-betaanaphth
3289: 2py-25thiaz-ala-betainyl3289: 2py-25thiaz-ala-betainyl
3290: 2py-24thiaz-bala-suabu3290: 2py-24thiaz-bala-suabu
3291: bhs-24thiaz-bala-betahni3291: bras-24thiaz-bala-betahni
3292: bhs-25methiaz-ser-betapy3292: bhs-25methiaz-ser-betapy
3293: phhs-oxadiaz-gly-betaheph3293: phhs-oxadiaz-gly-betaheph
3294: gua-2 thiaz-gly-suabu 45 3295: tolhs-25methiaz-bala-betacph3294: gua-2 thiaz-gly-suabu 45 3295: tolhs-25methiaz-bala-betacph
3296: ibhs-25thiaz-gly-betapy3296: ibhs-25thiaz-gly-betapy
3297: ibhs-24thioph-bala-betatos 3298: thpym-24thiaz-gly-betahdcph3297: ibhs-24thioph-bala-betatos 3298: thpym-24thiaz-gly-betahdcph
3299: tolhs-25methiaz-bala-aspibua 3300: thazep-25oxaz-gly-psdap 3301: tolhs-nme35pyr-bala-zdapch3299: tolhs-25methiaz-bala-aspibua 3300: thazep-25oxaz-gly-psdap 3301: tolhs-nme35pyr-bala-zdapch
5 3302: bhs-oxadiaz-gly-betaphethioa 3303: phhs-me24thioph-leu-betaph 3304: phhs-me25oxaz-gly-psdap5 3302: bhs-oxadiaz-gly-betaphethioa 3303: phhs-me24thioph-leu-betaph 3304: phhs-me25oxaz-gly-psdap
3305: tolhs-25methiaz-gly-betamethi 3306: ibhs-25oxaz-bala-betacbph 3307: bhs-25thiaz-leu-betapy3305: tolhs-25methiaz-gly-betamethi 3306: ibhs-25oxaz-bala-betacbph 3307: bhs-25thiaz-leu-betapy
10 3308 : ibhs-ithiadiaz-gly-betahdcph 3309: thpy-24oxaz-gly-betadcph 3310 : phhs-25thiaz-bala-betathioph 3311: bim-ithiadiaz-gly-aspaba 3312 : tolhs-ithiadiaz-bala-aspbzla10 3308: ibhs-ithiadiaz-gly-betahdcph 3309: thpy-24oxaz-gly-betadcph 3310: phhs-25thiaz-bala-betathioph 3311: bim-ithiadiaz-gly-aspaba 3312: tolhs-ithiadiaz-bala-aspbzla
15 3313: bim-24thioph-ala-zdap15 3313: bim-24thioph-ala-zdap
3314: ibhs-25oxaz-gly-betapyr3314: ibhs-25oxaz-gly-betapyr
3315: bhs-24thioph-gly-betaipro3315: bhs-24thioph-gly-betaipro
3316: bhs-24thiaz-bala-betaoxope3316: bhs-24thiaz-bala-betaoxope
3317: bhs-nme35pyr-gly-betah35dc 20 3318: phhs-oxadiaz-bala-betapym3317: bhs-nme35pyr-gly-betah35dc 20 3318: phhs-oxadiaz-bala-betapym
3319: tolhs-24thiaz-bala-betaheph3319: tolhs-24thiaz-bala-betaheph
3320: ibhs-ithiadiaz-gly-betaheph3320: ibhs-ithiadiaz-gly-betaheph
3321 : phhs-24thioph-gly-betaomebendi3321: phhs-24thioph-gly-betaomebendi
3322 : ibhs-ithiadiaz-bala-betacthioph3322: ibhs-ithiadiaz-bala-betacthioph
3323: bhs-ithiadiaz-gly-betamesu 25 3324: nmhs-24thioph-gly-betadcph3323: bhs-ithiadiaz-gly-betamesc 25 3324: nmhs-24thioph-gly-betadcph
3325: ibhs-24thiaz-bala-betatrif3325: ibhs-24thiaz-bala-betatrif
3326: bhs-oxadiaz-bala-betambiph3326: bras-oxadiaz-bala-betambiph
3327: bhs-oxadiaz-nmgly-betaipro3327: bhs-oxadiaz-nmgly-betaipro
3328 : bim-me24thioph-leu-beta34meoph 30 3329: 2pmhs-24thiaz-gly-betahbcph3328: bim-me24thioph-leu-beta34meoph 30 3329: 2 pmhs-24thiaz-gly-betahbcph
3330: tolhs-24thiaz-gly-betapy3330: tolhs-24thiaz-gly-betapy
3331 : ibhs-25oxaz-bala-betathiobe3331: ibhs-25oxaz-bala-betathiobe
3332: 2pmhs-42pym-gly-betapy3332: 2 pmhs-42pym-gly-betapy
3333: phhs-25methiaz-bala-betaph 35 3334: phhs-oxadiaz-gly-betafphe3333: phhs-25methiaz-bala-betaph 35 3334: phhs-oxadiaz-gly-betafphe
3335: tolhs-ithiadiaz-gly-betahmo3335: tolhs-ithiadiaz-gly-betahmo
3336: bhs-25oxaz-nmgly-betathioph3336: bhs-25oxaz-nmgly-betathioph
3337: bhs-42nmeim-gly-suabu3337: bhs-42nmeim-gly-suabu
3338: ibhs-24thiaz-bala-betah35dc3338: ibhs-24thiaz-bala-betah35dc
3339: bgua-24thioph-gly-betameph3339: bgua-24thioph-gly-betameph
40 3340: phhs-ithiadiaz-gly-betatos40 3340: phhs-ithiadiaz-gly-betatos
3341 : tolhs-oxadiaz-gly-beta34dcph3341: tolhs-oxadiaz-gly-beta34dcph
3342 : ibhs-25methiaz-bala-betaheph3342: ibhs-25methiaz-bala-betaheph
3343: bim-25fur-ala-zdap3343: bim-25fur-ala-zdap
3344: bim-24thioph-bala-betadcph 45 3345: ibhs-25oxaz-bala-betaf rif3344: bim-24thioph-bala-betadcph 45 3345: ibhs-25oxaz-bala-betaf rif
3346 : ibhs-oxadiaz-gly-beta34dcph3346: ibhs-oxadiaz-gly-beta34dcph
3347: tolhs-25thiaz-gly-betamesu 3348: bhs-oxadiaz-bala-betapy 3349 : impy-24thioph-bala-betaphethioa 3350: ibhs-24thioph-gly-betadcph 3351: bhs-ithiadiaz-gly-aspibua 5 3352: bhs-24oxaz-bala-zdap3347: tolhs-25thiaz-gly-betamesu 3348: bhs-oxadiaz-bala-betapy 3349: impy-24thioph-bala-betaphethioa 3350: ibhs-24thioph-gly-betadcph 3351: bhs-ithiadiaz-gly-aspibua 5 3352: bhs-24oxaz-bala-zdap
3353: tolhs-25thiaz-gly-betapytb3353: tolhs-25thiaz-gly-betapytb
3354 : phhs-oxadiaz-bala-betabenfu3354: phhs-oxadiaz-bala-betabenfu
3355: tolhs-24thiaz-bala-betahcbph3355: tolhs-24thiaz-bala-betahcbph
3356: bim-25thiaz-bala-betacph3356: bim-25thiaz-bala-betacph
3357: ibhs-25methiaz-bala-betatbuph3357: ibhs-25methiaz-bala-betatbuph
3358: tolhs-25thiaz-bala-betabthioph3358: tolhs-25thiaz-bala-betabthioph
3359: phhs-ithiadiaz-bala-betathio33359: phhs-ithiadiaz-bala-betathio3
3360: ibhs-24thioph-bala-busu2be3360: ibhs-24thioph-bala-busu2be
3361: 2py-53pyrazo-ala-betadcph3361: 2py-53pyrazo-ala-betadcph
3362 : tolhs-oxadiaz-gly-beta35dbph 15 3363: ibhs-ithiadiaz-bala-betahc3362: tolhs-oxadiaz-gly-beta35dbph 15 3363: ibhs-ithiadiaz-bala-betahc
3364: phhs-oxadiaz-bala-betapytb3364: phhs-oxadiaz-bala-betapytb
3365: phhs-oxadiaz-gly-betafbph3365: phhs-oxadiaz-gly-betafbph
3366 : tolhs-me24oxaz-gly-betadcph3366: tolhs-me24oxaz-gly-betadcph
3367: bhs-25oxaz-bala-betapytb 20 3368: phhs-24thiaz-gly-betahdbph3367: bhs-25oxaz-bala-betapytb 20 3368: phhs-24thiaz-gly-betahdbph
3369: bim-26py-ala-betainyl3369: bim-26py-ala-betainyl
3370: phhs-24thioph-gly-betambiph3370: phhs-24thioph-gly-betambiph
3371: bhs-nme35pyr-gly-betambiph3371: bhs-nme35pyr-gly-betambiph
3372: bhs-ithiadiaz-bala-betamesu3372: bhs-ithiadiaz-bala-betamesu
3373: tolhs-nme35pyr-gly-psdapch3373: tolhs-nme35pyr-gly-psdapch
3374: bhs-25oxaz-nmgly-betabpy3374: bhs-25oxaz-nmgly-betabpy
3375: tolhs-me24thioph-ala-betapy3375: tolhs-me24thioph-ala-betapy
3376: phhs-24thiaz-gly-betameph3376: phhs-24thiaz-gly-betameph
3377: phhs-25oxaz-gly-betaol3377: phhs-25oxaz-gly-betaol
3378: bim-24thioph-bala-betahc 30 3379: bhs-nme35pyr-ala-betabpy3378: bim-24thioph-bala-betahc 30 3379: bhs-nme35pyr-ala-betabpy
3380: ibhs-24thiaz-gly-betadhbfu3380: ibhs-24thiaz-gly-betadhbfu
3381: bhs-25oxaz-gly-betahbcph3381: bhs-25oxaz-gly-betahbcph
3382: tolhs-me24oxaz-leu-betaph3382: tolhs-me24oxaz-leu-betaph
3383 : 4pmhs-26py-gly-betapy 35 3384: ibhs-25thiaz-bala-betahbcph3383: 4 pmhs-26py-gly-betapy 35 3384: ibhs-25thiaz-bala-betahbcph
3385: tolhs-24thiaz-bala-betadcph3385: tolhs-24thiaz-bala-betadcph
3386 : tolhs-oxadiaz-bala-betainyl3386: tolhs-oxadiaz-bala-betainyl
3387: tolhs-25methiaz-bala-psdap3387: tolhs-25methiaz-bala-psdap
3388: phhs-me24thioph-bala-betadcph3388: phhs-me24thioph-bala-betadcph
3389 : phhs-oxadiaz-bala-betathio33389: phhs-oxadiaz-bala-betathio3
40 3390: phhs-24thioph-bala-asppha40 3390: phhs-24thioph-bala-asppha
3391: bhs-24thioph-bala-betainyl3391: bhs-24thioph-bala-betainyl
3392: bhs-25oxaz-gly-betafluo3392: bhs-25oxaz-gly-betafluo
3393: ibhs-nme35pyr-bala-psdapee3393: ibhs-nme35pyr-bala-psdapee
3394: bim-me25oxaz-leu-betadcph 45 3395: tolhs-ithiadiaz-bala-betafu23394: bim-me25oxaz-leu-betadcph 45 3395: tolhs-ithiadiaz-bala-betafu2
3396: phhs-25methiaz-gly-betabthioph3396: phhs-25methiaz-gly-beta thioph
3397: bhs-24thiaz-bala-betafbph 3398: ibhs-nme35pyr-bala-betafluo3397: bras-24thiaz-bala-betafbph 3398: ibhs-nme35pyr-bala-betafluo
3399: bhs-ithiadiaz-nmgly-betal3bendi3399: bhs-ithiadiaz-nmgly-betal3bendi
3400: bhs-24thiaz-gly-betaol3400: bhs-24thiaz-gly-betaol
3401: ibhs-oxadiaz-gly-suabu 5 3402: nmhs-42nmeim-gly-psdap3401: ibhs-oxadiaz-gly-suabu 5 3402: nmhs-42nmeim-gly-psdap
3403: phhs-25methiaz-bala-asppha3403: phhs-25methiaz-bala-asppha
3404: gua-26py-gly-beta34dcph3404: gua-26py-gly-beta34dcph
3405 : phhs-ithiadiaz-bala-betadbph3405: phhs-ithiadiaz-bala-betadbph
3406: phhs-me25thioph-gly-psdap3406: phhs-me25thioph-gly-psdap
3407: bhs-24thiaz-bala-betabediox3407: bhs-24thiaz-bala-betabediox
1010
3408: bim-25thioph-ala-betadcph3408: bim-25thioph-ala-betadcph
3409: bhs-ithiadiaz-ala-ibsdap3409: bhs-ithiadiaz-ala-ibsdap
3410: ibhs-25thiaz-bala-aspibua3410: ibhs-25thiaz-bala-aspibua
3411: bhs-24thioph-bala-beta4bph3411: bhs-24thioph-bala-beta4bph
3412 : ibhs-ithiadiaz-bala-betabnaphth 15 3413: 2py-25methiaz-gly-betathio33412: ibhs-ithiadiaz-bala-betabnaphth 15 3413: 2py-25methiaz-gly-betathio3
3414: bhs-ithiadiaz-gly-betampy3414: bhs-ithiadiaz-gly-betampy
3415: phhs-nme35pyr-gly-betamethi3415: phhs-nme35pyr-gly-betamethi
3416 : ibhs-24thioph-bala-beta34meoph3416: ibhs-24thioph-bala-beta34meoph
3417: ibhs-25oxaz-bala-betafu3 20 3418: phhs-ithiadiaz-gly-betaimid3417: ibhs-25oxaz-bala-betafu3 20 3418: phhs-ithiadiaz-gly-betaimid
3419: tolhs-25oxaz-gly-betadcphch3419: tolhs-25oxaz-gly-betadcphch
3420 : tolhs-24thioph-bala-betafbph3420: tolhs-24thioph-bala-betafbph
3421: ibhs-25thiaz-bala-betatbuph3421: ibhs-25thiaz-bala-betatbuph
3422: bhs-25oxaz-gly-psdaptb3422: bhs-25oxaz-gly-psdaptb
3423: bim-me24thioph-bala-betaph3423: bim-me24thioph-bala-betaph
25 3424: bhs-24thiaz-gly-beta3quin25 3424: bhs-24thiaz-gly-beta3quin
3425: bim-me24thiaz-leu-betadcph3425: bim-me24thiaz-leu-betadcph
3426 : phhs-ithiadiaz-gly-betal3bendi3426: phhs-ithiadiaz-gly-betal3bendi
3427 : tolhs-25methiaz-gly-aspibua3427: tolhs-25methiaz-gly-aspibua
3428: tolhs-24thiaz-gly-betadhbfu 30 3429: bhs-42pym-ala-betadcph3428: tolhs-24thiaz-gly-betadhbfu 30 3429: bhs-42pym-ala-betadcph
3430 : ibhs-nme35pyr-bala-betacthioph3430: ibhs-nme35pyr-bala-betacthioph
3431: bhs-25oxaz-gly-betaanaphth3431: bhs-25oxaz-gly-betaanaphth
3432: ibhs-ithiadiaz-gly-betatos3432: ibhs-ithiadiaz-gly-betatos
3433: ibhs-nme35pyr-bala-betadcph 35 3434: ibhs-nrrte35pyr-bala-betatos3433: ibhs-nme35pyr-bala-betadcph 35 3434: ibhs-nrrte35pyr-bala-betatos
3435 : tolhs-nme35pyr-bala-betahbcph3435: tolhs-nme35pyr-bala-betahbcph
3436: 2py-me25thioph-ala-betaph3436: 2py-me25thioph-ala-betaph
3437: ibhs-oxadiaz-gly-busu2be3437: ibhs-oxadiaz-gly-busu2be
3438: bim-triaz-bala-zdap3438: bim-triaz-bala-zdap
3439: bhs-24thioph-gly-betampy3439: bhs-24thioph-gly-betampy
40 3440: bhs-35fur-bala-betapy40 3440: bhs-35fur-bala-betapy
3441 : bhs-me24thioph-leu-beta34meoph3441: bhs-me24thioph-leu-beta34meoph
3442 : ibhs-25oxaz-bala-betaanaphth3442: ibhs-25oxaz-bala-betaanaphth
3443: bhs-25oxaz-leu-zdap3443: bras-25oxaz-leu-zdap
3444: gua-24thiaz-gly-betadmoph 45 3445: bhs-ithiadiaz-bala-betacthioph3444: gua-24thiaz-gly-betadmoph 45 3445: bhs-ithiadiaz-bala-betacthioph
3446: bhs-25 hiaz-gly-betapyr3446: bhs-25 hiaz-gly-betapyr
3447 : ibhs-ithiadiaz-gly-beta34dcph 3448: tolhs-oxadiaz-bala-betaheph 3449: tolhs-oxadiaz-gly-betapyee 3450: gua-24oxaz-gly-betambiph 3451: tolhs-24thioph-gly-betafu3 5 3452: tolhs-24thiaz-bala-zdaptb 3453 : tolhs-ithiadiaz-gly-betaoxope3447: ibhs-ithiadiaz-gly-beta34dcph 3448: tolhs-oxadiaz-bala-betaheph 3449: tolhs-oxadiaz-gly-betapyee 3450: gua-24oxaz-gly-betambiph 3451: tolhs-24thioph-gly-betafu3 5 3452: tolhs-24thiaz-bala-zdaptb 3453: tolhs- ithiadiaz-gly-betaoxope
3454: phhs-nme35pyr-gly-betaftrif3454: phhs-nme35pyr-gly-betaftrif
3455: bhs-ithiadiaz-bala-betadcphtb3455: bhs-ithiadiaz-bala-betadcphtb
3456: bim-triaz-bala-psdap3456: bim-triaz-bala-psdap
3457: bhs-nme35pyr-gly-betapyr3457: bhs-nme35pyr-gly-betapyr
1010
3458: bhs-25oxaz-bala-betaipro3458: bhs-25oxaz-bala-betaipro
3459: tolhs-nme35pyr-gly-betabmph3459: tolhs-nme35pyr-gly-betabmph
3460: ibhs-24thiaz-bala-betadmph3460: ibhs-24thiaz-bala-betadmph
3461: tolhs-24thiaz-gly-betaphethio3461: tolhs-24thiaz-gly-betaphethio
3462: agua-26py-gly-betadcph 15 3463: 2py-triaz-gly-psdap3462: agua-26py-gly-betadcph 15 3463: 2py-triaz-gly-psdap
3464 : 2py-24thiaz-bala-betabnaphth3464: 2py-24thiaz-bala-betabnaphth
3465: tolhs-oxadiaz-bala-betaph3465: tolhs-oxadiaz-bala-betaph
3466: ibhs-25methiaz-gly-aspaba3466: ibhs-25methiaz-gly-aspaba
3467: bim-me24thiaz-gly-betaph 2o 3468: bim-me24thioph-ala-betapy3467: bim-me24thiaz-gly-betaph 2o 3468: bim-me24thioph-ala-betapy
3469 : ibhs-24thiaz-bala-betaanaphth3469: ibhs-24thiaz-bala-betaanaphth
3470: bim-42nmeim-ala-betapy3470: bim-42nmeim-ala-betapy
3471: ibhs-24thioph-bala-betahni3471: ibhs-24thioph-bala-betahni
3472: bhs-24thioph-bala-asppha3472: bhs-24thioph-bala-asppha
3473: ibhs-24thiaz-bala-betahph3473: ibhs-24thiaz-bala-betahph
25 3474: bhs-25oxaz-bala-betahc25 3474: bras-25oxaz-bala-betahc
3475: tolhs-24thioph-gly-betah35dc3475: tolhs-24thioph-gly-betah35dc
3476 : bim-me24thioph-ala-beta34meoph3476: bim-me24thioph-ala-beta34meoph
3477 : bim-me25oxaz-bala-beta34meoph3477: bim-me25oxaz-bala-beta34meoph
3478: tolhs-25thiaz-bala-aspaba 30 3479: ibhs-oxadiaz-bala-betampy3478: tolhs-25thiaz-bala-aspaba 30 3479: ibhs-oxadiaz-bala-betampy
3480: bhs-35thioph-ala-betapy3480: bhs-35thioph-ala-betapy
3481 : tolhs-24thioph-bala-betafph3481: tolhs-24thioph-bala-betafph
3482 : bhs-nme35pyr-bala-ibsdap3482: bhs-nme35pyr-bala-ibsdap
3483: 2pmhs-24thioph-bala-betapyr 35 3484: phhs-24thiaz-gly-betafphe3483: 2 pmhs-24thioph-bala-betapyr 35 3484: phhs-24thiaz-gly-betafphe
3485: bhs-25oxaz-bala-betacbph3485: bras-25oxaz-bala-betacbph
3486: tolhs-24thioph-gly-zdaptb3486: tolhs-24thioph-gly-zdaptb
3487: bim-me24thiaz-leu-betapy3487: bim-me24thiaz-leu-betapy
3488: bim-ithiadiaz-leu-betapy3488: bim-ithiadiaz-leu-betapy
3489 : ibhs-ithiadiaz-bala-beta34dcph3489: ibhs-ithiadiaz-bala-beta34dcph
40 3490: bhs-oxadiaz-bala-csdap40 3490: bras-oxadiaz-bala-csdap
3491: phhs-25methiaz-bala-aspbzla3491: phhs-25methiaz-bala-aspbzla
3492: 2py-me24oxaz-gly-psdap3492: 2py-me24oxaz-gly-psdap
3493: bhs-24thioph-gly-csdap3493: bhs-24thioph-gly-csdap
3494 : phhs-ithiadiaz-bala-betadcphch 45 3495: ibhs-nme35pyr-gly-asppha3494: phhs-ithiadiaz-bala-betadcphch 45 3495: ibhs-nme35pyr-gly-asppha
3496: bhs-oxadiaz-gly-betaftrif3496: bhs-oxadiaz-gly-betaftrif
3497 : bhs-25methiaz-bala-betabenfu 3498: gua-24thiaz-gly-betaomebendi3497: bras-25methiaz-bala-betabenfu 3498: gua-24thiaz-gly-betaomebendi
3499 : bhs-me25thiaz-gly-beta34meoph3499: bhs-me25thiaz-gly-beta34meoph
3500: bim-25methiaz-bala-betampy3500: bim-25methiaz-bala-betampy
3501 : phhs-25oxaz-gly-betaphethio 5 3502: tolhs-24thiaz-gly-zdap3501: phhs-25oxaz-gly-betaphethio 5 3502: tolhs-24thiaz-gly-zdap
3503: bhs-nme35pyr-bala-betacph3503: bhs-nme35pyr-bala-betacph
3504 : tolhs-nme35pyr-gly-betabdimo3504: tolhs-nme35pyr-gly-betabdimo
3505: bhs-nme35pyr-bala-betadcphch3505: bhs-nme35pyr-bala-betadcphch
3506 : bhs-25thiaz-bala-betabnaphth3506: bras-25thiaz-bala-betabnaphth
3507: bhs-25thiaz-bala-betaph3507: bras-25thiaz-bala-betaph
1010
3508: tolhs-oxadiaz-gly-betatrif3508: tolhs-oxadiaz-gly-betatrif
3509: 2py-me24oxaz-leu-beta34meoph3509: 2py-me24oxaz-leu-beta34meoph
3510 : tolhs-ithiadiaz-bala-betathiome3510: tolhs-ithiadiaz-bala-betathiome
3511: tolhs-25thiaz-bala-betapych3511: tolhs-25thiaz-bala-betapych
3512: tolhs-25oxaz-gly-betabediox 15 3513: tolhs-25methiaz-bala-betapym3512: tolhs-25oxaz-gly-betabediox 15 3513: tolhs-25methiaz-bala-betapym
3514: bhs-25thiaz-gly-betambiph3514: bhs-25thiaz-gly-betambiph
3515: phhs-ithiadiaz-bala-betaoxaz3515: phhs-ithiadiaz-bala-betaoxaz
3516: 2py-42oxaz-bala-betadcph3516: 2py-42oxaz-bala-betadcph
3517: bhs-nme35pyr-gly-psdapee 20 3518: gua-24oxaz-gly-betafph3517: bhs-nme35pyr-gly-psdapee 20 3518: gua-24oxaz-gly-betafph
3519: phhs-24thioph-bala-betafphe3519: phhs-24thioph-bala-betafphe
3520: bhs-25thiaz-bala-betapytb3520: bhs-25thiaz-bala-betapytb
3521: phhs-24thiaz-bala-betadcphch3521: phhs-24thiaz-bala-betadcphch
3522: phhs-25thiaz-bala-betapyr3522: phhs-25thiaz-bala-betapyr
3523: tolhs-nme35pyr-gly-psdaptb3523: tolhs-nme35pyr-gly-psdaptb
2525
3524: tolhs-nme35pyr-bala-suabu3524: tolhs-nme35pyr-bala-suabu
3525: bhs-42oxaz-bala-betadcph3525: bras-42oxaz-bala-betadcph
3526 : phhs-25methiaz-gly-betapych3526: phhs-25methiaz-gly-betapych
3527 : impy-25methiaz-bala-betainyl3527: impy-25methiaz-bala-betainyl
3528: phhs-25thiaz-gly-ibsdap 30 3529: phhs-25oxaz-gly-betabnaphth3528: phhs-25thiaz-gly-ibsdap 30 3529: phhs-25oxaz-gly-betabnaphth
3530: bhs-oxadiaz-gly-betatos3530: bras-oxadiaz-gly-betatos
3531: tolhs-25thiaz-gly-betambiph3531: tolhs-25thiaz-gly-betambiph
3532: bhs-25methiaz-bala-psdaptb3532: bhs-25methiaz-bala-psdaptb
3533 : impy-24thiaz-gly-betathiobe 35 3534: bhs-25methiaz-bala-betamethioph3533: impy-24thiaz-gly-betathiobe 35 3534: bhs-25methiaz-bala-betamethioph
3535: bhs-25thiaz-nmgly-betainyl3535: bhs-25thiaz-nmgly-betainyl
3536: bhs-ithiadiaz-bala-betadito3536: bhs-ithiadiaz-bala-betadito
3537: gua-24thiaz-gly-betabenfu3537: gua-24thiaz-gly-betabenfu
3538: ibhs-24thiaz-bala-betadtrif3538: ibhs-24thiaz-bala-betadtrif
3539: phhs-me25thioph-leu-betapy3539: phhs-me25thioph-leu-betapy
40 3540: phhs-me25thiaz-gly-betaph40 3540: phhs-me25thiaz-gly-betaph
3541 : ibhs-ithiadiaz-gly-betabnaphth3541: ibhs-ithiadiaz-gly-betabnaphth
3542 : ibhs-25oxaz-gly-betahbcph3542: ibhs-25oxaz-gly-betahbcph
3543: bhs-25thiaz-nmgly-beta3quin3543: bhs-25thiaz-nmgly-beta3quin
3544: impy-24thioph-gly-betahmofu 45 3545: bhs-24thioph-gly-betapym3544: impy-24thioph-gly-betahmofu 45 3545: bhs-24thioph-gly-betapym
3546: 2py-52thiaz-gly-zdap3546: 2py-52thiaz-gly-zdap
3547: phhs-oxadiaz-bala-betaibph 3548 : 2pmhs-25methiaz-bala-beta4bph3547: phhs-oxadiaz-bala-betaibph 3548: 2 pmhs-25methiaz-bala-beta4bph
3549: tolhs-25methiaz-gly-betaet3549: tolhs-25methiaz-gly-betaet
3550: bhs-25thiaz-ala-betahmph3550: bhs-25thiaz-ala-betahmph
3551: bhs-25thioph-leu-betapy 5 3552: bhs-25methiaz-gly-suabu3551: bhs-25thioph-leu-betapy 5 3552: bhs-25methiaz-gly-suabu
3553: phhs-oxadiaz-bala-suabu3553: phhs-oxadiaz-bala-suabu
3554: phhs-25thiaz-bala-psdap3554: phhs-25thiaz-bala-psdap
3555: phhs-me24thioph-leu-psdap3555: phhs-me24thioph-leu-psdap
3556: bim-24thioph-gly-betaibph3556: bim-24thioph-gly-betaibph
3557: ibhs-oxadiaz-gly-betapy3557: ibhs-oxadiaz-gly-betapy
10 3558: tolhs-24thiaz-bala-betaanaphth10 3558: tolhs-24thiaz-bala-betaanaphth
3559 : phhs-oxadiaz-bala-betaoxope3559: phhs-oxadiaz-bala-betaoxope
3560: bhs-24thiaz-bala-betapyee3560: bras-24thiaz-bala-betapyee
3561: ibhs-24thiaz-gly-betahb3561: ibhs-24thiaz-gly-betahb
3562 : tolhs-oxadiaz-bala-betahdbph 15 3563: bhs-24thiaz-gly-betabph3562: tolhs-oxadiaz-bala-betahdbph 15 3563: bhs-24thiaz-gly-betabph
3564: bhs-ithiadiaz-ala-beta34dcph3564: bhs-ithiadiaz-ala-beta34dcph
3565: ibhs-24thiaz-bala-betatbuph3565: ibhs-24thiaz-bala-betatbuph
3566: ibhs-24thiaz-gly-betaipro3566: ibhs-24thiaz-gly-betaipro
3567: bhs-ithiadiaz-ala-betadcph 20 3568: bhs-25thiaz-bala-betafbph3567: bhs-ithiadiaz-ala-betadcph 20 3568: bhs-25thiaz-bala-betafbph
3569: phhs-25oxaz-gly-zdapch3569: phhs-25oxaz-gly-zdapch
3570: ibhs-24thiaz-gly-betabediox3570: ibhs-24thiaz-gly-betabediox
3571 : ibhs-25methiaz-gly-betadmoph3571: ibhs-25methiaz-gly-betadmoph
3572: phhs-24thioph-gly-betaipr3572: phhs-24thioph-gly-betaipr
3573: bhs-ithiadiaz-bala-betabph3573: bhs-ithiadiaz-bala-betabph
25 3574: tolhs-nme35pyr-gly-psdapee25 3574: tolhs-nme35pyr-gly-psdapee
3575: bim-42oxaz-bala-psdap3575: bim-42oxaz-bala-psdap
3576: ibhs-25oxaz-bala-betafluo3576: ibhs-25oxaz-bala-betafluo
3577: tolhs-nme35pyr-gly-betahmo3577: tolhs-nme35pyr-gly-betahmo
3578: bhs-25methiaz-bala-aspaba 30 3579: bhs-25thioph-gly-zdap3578: bhs-25methiaz-bala-aspaba 30 3579: bhs-25thioph-gly-zdap
3580: phhs-25oxaz-gly-betadmph3580: phhs-25oxaz-gly-betadmph
3581: bhs-oxadiaz-bala-betapyr3581: bras-oxadiaz-bala-betapyr
3582: gua-26py-gly-betamethioph3582: gua-26py-gly-betamethioph
3583: 2py-25thioph-bala-betapy 35 3584: bhs-oxadiaz-ala-betathioph3583: 2py-25thioph-bala-betapy 35 3584: bhs-oxadiaz-ala-betathioph
3585: bim-thiadiaz-bala-zdap3585: bim-thiadiaz-bala-zdap
3586: bim-25oxaz-bala-betarnethioph3586: bim-25oxaz-bala-betarnethioph
3587: bhs-25methiaz-nmgly-betamesu3587: bhs-25methiaz-nmgly-betamesu
3588: dhpyrr-26py-gly-betadcph3588: dhpyrr-26py-gly-betadcph
3589 : 2py-me25thiaz-gly-beta34meoph3589: 2py-me25thiaz-gly-beta34meoph
40 3590: phhs-oxadiaz-gly-betahcbph40 3590: phhs-oxadiaz-gly-betahcbph
3591: 2py-me25thioph-gly-beta34meoph3591: 2py-me25thioph-gly-beta34meoph
3592 : phhs-25methiaz-gly-betaibph3592: phhs-25methiaz-gly-betaibph
3593: ibhs-nme35pyr-bala-betamesu3593: ibhs-nme35pyr-bala-betamesu
3594: ibhs-24thioph-bala-betabpy 45 3595: ibhs-24thioph-bala-betadcphee3594: ibhs-24thioph-bala-betabpy 45 3595: ibhs-24thioph-bala-betadcphee
3596 : ibhs-oxadiaz-gly-betacthioph3596: ibhs-oxadiaz-gly-betacthioph
3597: gua-24oxaz-gly-betathiome 3598: gua-42pym-gly-betaoxope3597: gua-24oxaz-gly-betathioma 3598: gua-42pym-gly-betaoxope
3599: 2py-25oxaz-gly-aspbzla3599: 2py-25oxaz-gly-aspbzla
3600: bhs-oxadiaz-gly-betadhbfu3600: bhs-oxadiaz-gly-betadhbfu
3601 : phhs-25methiaz-bala-betacthioph 5 3602: bim-25methiaz-bala-betaipro3601: phhs-25methiaz-bala-betacthioph 5 3602: bim-25methiaz-bala-betaipro
3603 : ibhs-ithiadiaz-gly-betadito3603: ibhs-ithiadiaz-gly-betadito
3604: tolhs-nme35pyr-bala-betahdbph3604: tolhs-nme35pyr-bala-betahdbph
3605: bim-me24thioph-gly-beta34meoph3605: bim-me24thioph-gly-beta34meoph
3606: phhs-me24thioph-gly-betapy3606: phhs-me24thioph-gly-betapy
3607: bhs-35fur-leu-psdap3607: bras-35fur-leu-psdap
3608: ibhs-24thiaz-gly-betadmph3608: ibhs-24thiaz-gly-betadmph
3609: dhim-24thiaz-gly-betainyl3609: dhim-24thiaz-gly-betainyl
3610: bhs-42oxaz-gly-betadcph3610: bras-42oxaz-gly-betadcph
3611: ibhs-24thiaz-bala-betaet3611: ibhs-24thiaz-bala-betet
3612: phhs-nme35pyr-gly-betahb 15 3613: gua-24thiaz-gly-betabpy3612: phhs-nme35pyr-gly-betahb 15 3613: gua-24thiaz-gly-betabpy
3614: 2py-52thiaz-gly-psdap3614: 2py-52thiaz-gly-psdap
3615: tolhs-25methiaz-bala-suabu3615: tolhs-25methiaz-bala-suabu
3616: phhs-25oxaz-gly-betabdimo3616: phhs-25oxaz-gly-betabdimo
3617: bhs-nme35pyr-nmgly-betadmph 20 3618: ibhs-oxadiaz-gly-betadmoph3617: bhs-nme35pyr-nmgly-betadmph 20 3618: ibhs-oxadiaz-gly-betadmoph
3619: phhs-nme35pyr-gly-aspaba3619: phhs-nme35pyr-gly-aspaba
3620: phhs-nme35pyr-bala-betamesu3620: phhs-nme35pyr-bala-betamesu
3621 : bhs-25thiaz-bala-betathiobe3621: bras-25thiaz-bala-betathiobe
3622: bhs-24thiaz-leu-psdap3622: bhs-24thiaz-leu-psdap
3623: bhs-25thiaz-gly-betadtrif 25 3624: ibhs-25methiaz-gly-betapyee3623: bhs-25thiaz-gly-betadtrif 25 3624: ibhs-25methiaz-gly-betapyee
3625: bim-35thioph-gly-psdap3625: bim-35thioph-gly-psdap
3626: bhs-25oxaz-gly-betadtrif3626: bras-25oxaz-gly-betadtrif
3627: bhs-oxadiaz-bala-betadcph3627: bras-oxadiaz-bala-betadcph
3628: bim-25thiaz-ala-betapy 30 3629: 2py-24thiaz-gly-asppha3628: bim-25thiaz-ala-betapy 30 3629: 2py-24thiaz-gly-asppha
3630: bhs-oxadiaz-gly-betaamibe3630: bhs-oxadiaz-gly-betaamibe
3631: bhs-ithiadiaz-nmgly-beta34dcph3631: bhs-ithiadiaz-nmgly-beta34dcph
3632: bim-24thiaz-gly-betameph3632: bim-24thiaz-gly-betameph
3633: phhs-me24oxaz-gly-psdap 35 3634: bim-me24thiaz-gly-psdap3633: phhs-me24oxaz-gly-psdap 35 3634: bim-me24thiaz-gly-psdap
3635: bhs-oxadiaz-gly-betaheph3635: bhs-oxadiaz-gly-betaheph
3636: thpy -24thioph-gly-betadcph3636: thpy-24thioph-gly-betadcph
3637: gua-25thioph-gly-betaoxope3637: gua-25thioph-gly-betaoxope
3638: bhs-42pym-gly-betameph3638: bhs-42pym-gly-betameph
3639: bhs-24thiaz-gly-betafu23639: bhs-24thiaz-gly-betafu2
40 3640: tolhs-25oxaz-gly-betaheph40 3640: tolhs-25oxaz-gly-betaheph
3641: bhs-25oxaz-nmgly-betahmph3641: bhs-25oxaz-nmgly-betahmph
3642: impy-25oxaz-gly-betapym3642: impy-25oxaz-gly-betapym
3643: gua-25thiaz-gly-betamethi3643: gua-25thiaz-gly-betamethi
3644 : phhs-oxadiaz-bala-betacthioph 45 3645: bhs-24thioph-gly-betaibph3644: phhs-oxadiaz-bala-betacthioph 45 3645: bhs-24thioph-gly-betaibph
3646: phhs-25methiaz-bala-betahmofu3646: phhs-25methiaz-bala-betahmofu
3647: bhs-25oxaz-gly-betacthioph 3648: bhs-oxadiaz-bala-betaipr3647: bhs-25oxaz-gly-betacthioph 3648: bras-oxadiaz-bala-betaipr
3649: phhs-24thioph-gly-betaamibe3649: phhs-24thioph-gly-betaamibe
3650: phhs-nme35pyr-gly-betaamibe3650: phhs-nme35pyr-gly-betaamibe
3651 : phhs-25methiaz-gly-betaphethio 5 3652: phhs-25thiaz-gly-betapbiph3651: phhs-25methiaz-gly-betaphethio 5 3652: phhs-25thiaz-gly-betapbiph
3653: ibhs-25oxaz-gly-betapy3653: ibhs-25oxaz-gly-betapy
3654: tolhs-nme35pyr-gly-aspibua3654: tolhs-nme35pyr-gly-aspibua
3655: ibhs-24thiaz-gly-psdapch3655: ibhs-24thiaz-gly-psdapch
3656: 2py-35fur-ala-psdap3656: 2py-35fur-ala-psdap
3657 : tolhs-24thiaz-bala-betaomebendi3657: tolhs-24thiaz-bala-betaomebendi
10 3658: ibhs-25methiaz-bala-betadhbfu10 3658: ibhs-25methiaz-bala-betadhbfu
3659 : ibhs-25methiaz-bala-betaoxaz3659: ibhs-25methiaz-bala-betaoxaz
3660: bim-25methiaz-gly-asppha3660: bim-25methiaz-gly-asppha
3661: phhs-ithiadiaz-bala-betadmoph3661: phhs-ithiadiaz-bala-betadmoph
3662: bhs-35fur-ala-betadcph 15 3663: phhs-25thiaz-bala-betatos3662: bhs-35fur-ala-betadcph 15 3663: phhs-25thiaz-bala-betatos
3664: bim-42nmeim-gly-betafu33664: bim-42nmeim-gly-betafu3
3665: bhs-24thioph-gly-beta35dbph3665: bhs-24thioph-gly-beta35dbph
3666: ibhs-nme35pyr-bala-betadhbfu3666: ibhs-nme35pyr-bala-betadhbfu
3667: cima-24thiaz-bala-psdap 20 3668: tolhs-25methiaz-bala-betaol3667: cima-24thiaz-bala-psdap 20 3668: tolhs-25methiaz-bala-betaol
3669: gua-26py-gly-betaipr3669: gua-26py-gly-betaipr
3670: tolhs-ithiadiaz-bala-betaipr3670: tolhs-ithiadiaz-bala-betaipr
3671: ibhs-nme35pyr-gly-csdap3671: ibhs-nme35pyr-gly-csdap
3672: tolhs-24thiaz-gly-betafph3672: tolhs-24thiaz-gly-betafph
3673 : phhs-25methiaz-bala-betaphethio3673: phhs-25methiaz-bala-betaphethio
25 3674: phhs-ithiadiaz-bala-betafphe25 3674: phhs-ithiadiaz-bala-betafphe
3675: tolhs-24thioph-bala-beta23meoph3675: tolhs-24thioph-bala-beta23meoph
3676: phhs-25thiaz-bala-aspbzla3676: phhs-25thiaz-bala-aspbzla
3677: tolhs-oxadiaz-gly-betacbph3677: tolhs-oxadiaz-gly-betacbph
3678: bhs-24thiaz-ala-betabnaphth 30 3679: phhs-25methiaz-bala-betapbiph3678: bhs-24thiaz-ala-betabnaphth 30 3679: phhs-25methiaz-bala-betapbiph
3680: 2py-24im-ala-psdap3680: 2py-24im-ala-psdap
3681: tolhs-24thiaz-bala-betathiobe3681: tolhs-24thiaz-bala-betathiobe
3682 : phhs-oxadiaz-gly-betaphethio3682: phhs-oxadiaz-gly-betaphethio
3683: tolhs-25oxaz-gly-betahbcph 35 3684: tolhs-oxadiaz-bala-betacbph3683: tolhs-25oxaz-gly-betahbcph 35 3684: tolhs-oxadiaz-bala-betacbph
3685: tolhs-25oxaz-gly-beta34meoph3685: tolhs-25oxaz-gly-beta34meoph
3686: bhs-25oxaz-gly-betathiome3686: bhs-25oxaz-gly-betathioma
3687: dhim-42nmeim-gly-zdap3687: dhim-42nmeim-gly-zdap
3688: ibhs-ithiadiaz-gly-betabthioph3688: ibhs-ithiadiaz-gly-betabthioph
3689: ibhs-oxadiaz-gly-betaet3689: ibhs-oxadiaz-gly-betet
40 3690 : bhs-25methiaz-nmgly-beta34dcph40 3690: bhs-25methiaz-nmgly-beta34dcph
3691 : ibhs-25oxaz-gly-beta23meoph3691: ibhs-25oxaz-gly-beta23meoph
3692: phhs-25methiaz-gly-betacph3692: phhs-25methiaz-gly-betacph
3693: ibhs-nme35pyr-gly-betathio33693: ibhs-nme35pyr-gly-betathio3
3694: bim-me24thiaz-gly-betadcph 45 3695: phhs-24thioph-gly-csdap3694: bim-me24thiaz-gly-betadcph 45 3695: phhs-24thioph-gly-csdap
3696: ibhs-nme35pyr-bala-asppha3696: ibhs-nme35pyr-bala-asppha
3697: 2py-me24thioph-ala-psdap 3698: tolhs-25oxaz-gly-zdapee 3699: dhim-26py-gly-psdap 3700: 2py-25thioph-bala-zdap3697: 2py-me24thioph-ala-psdap 3698: tolhs-25oxaz-gly-zdapee 3699: dhim-26py-gly-psdap 3700: 2py-25thioph-bala-zdap
3701: tolhs-25oxaz-bala-psdapch 5 3702: phhs-24thioph-gly-zdapch3701: tolhs-25oxaz-bala-psdapch 5 3702: phhs-24thioph-gly-zdapch
3703: bim-thiadiaz-bala-betadcph3703: bim-thiadiaz-bala-betadcph
3704: bim-24oxaz-bala-betadcph3704: bim-24oxaz-bala-betadcph
3705: tolhs-25oxaz-gly-psdap3705: tolhs-25oxaz-gly-psdap
3706: bim-52thiaz-gly-zdap3706: bim-52thiaz-gly-zdap
3707: ibhs-oxadiaz-bala-betadito3707: ibhs-oxadiaz-bala-betadito
10 3708: bhs-me24thiaz-bala-zdap10 3708: bhs-me24thiaz-bala-zdap
3709: 2py-ithiadiaz-bala-asppha3709: 2py-ithiadiaz-bala-asppha
3710: gua-42pym-gly-betafu23710: gua-42pym-gly-betafu2
3711 : phhs-25methiaz-bala-betaanaphth3711: phhs-25methiaz-bala-betaanaphth
3712: bhs-26py-ala-zdap 15 3713: ibhs-24thiaz-gly-betaoxope3712: bhs-26py-ala-zdap 15 3713: ibhs-24thiaz-gly-betaoxope
3714 : phhs-24thioph-bala-betadcphee3714: phhs-24thioph-bala-betadcphee
3715: dhim-52thiaz-ala-betainyl3715: dhim-52thiaz-ala-betainyl
3716 : phhs-ithiadiaz-bala-betaanaphth3716: phhs-ithiadiaz-bala-betaanaphth
3717: bhs-24thioph-gly-betafph 20 3718: gua-24thiaz-gly-betahb3717: bhs-24thioph-gly-betafph 20 3718: gua-24thiaz-gly-betahb
3719: bhs-oxadiaz-gly-betaipro3719: bhs-oxadiaz-gly-betaipro
3720 : phhs-25methiaz-gly-betatrif3720: phhs-25methiaz-gly-betatrif
3721: bim-me24thioph-gly-zdap3721: bim-me24thioph-gly-zdap
3722: ibhs-oxadiaz-bala-betaoxaz3722: ibhs-oxadiaz-bala-betaoxaz
3723: gua-24thiaz-gly-betacbph3723: gua-24thiaz-gly-betacbph
25 3724: ibhs-ithiadiaz-gly-betahni25 3724: ibhs-ithiadiaz-gly-betahni
3725: bim-ithiadiaz-bala-aspibua3725: bim-ithiadiaz-bala-aspibua
3726: 2py-42oxaz-gly-betadcph3726: 2py-42oxaz-gly-betadcph
3727: tolhs-ithiadiaz-gly-betaet3727: tolhs-ithiadiaz-gly-betet
3728: ibhs-25methiaz-bala-betahdcph 30 3729: 2py-42nmeim-gly-betacph3728: ibhs-25methiaz-bala-betahdcph 30 3729: 2py-42nmeim-gly-betacph
3730 : tolhs-oxadiaz-bala-betaanaphth3730: tolhs-oxadiaz-bala-betaanaphth
3731 : phhs-ithiadiaz-gly-betaanaphth3731: phhs-ithiadiaz-gly-betaanaphth
3732 : phhs-ithiadiaz-gly-betafluo3732: phhs-ithiadiaz-gly-betafluo
3733 : tolhs-ithiadiaz-bala-betaftrif 35 3734: phhs-oxadiaz-gly-betaet3733: tolhs-ithiadiaz-bala-betaftrif 35 3734: phhs-oxadiaz-gly-betet
3735: phhs-24thiaz-bala-csdap3735: phhs-24thiaz-bala-csdap
3736: ibhs-25oxaz-bala-psdap3736: ibhs-25oxaz-bala-psdap
3737: 2pmhs-25oxaz-gly-betaol3737: 2 pmhs-25oxaz-gly-betaol
3738: tolhs-oxadiaz-gly-betadcph3738: tolhs-oxadiaz-gly-betadcph
3739: phhs-24thioph-bala-betamesu3739: phhs-24thioph-bala-betamesu
40 3740: bhs-25thiaz-gly-betadito40 3740: bhs-25thiaz-gly-betadito
3741: 2py-42pym-ala-betainyl3741: 2py-42pym-ala-betainyl
3742: tolhs-me25oxaz-gly-zdap3742: tolhs-me25oxaz-gly-zdap
3743: 2pmhs-25oxaz-gly-beta3quin3743: 2 pmhs-25oxaz-gly-beta3quin
3744: phhs-24thiaz-bala-betahmo 45 3745: tolhs-24thiaz-bala-csdap3744: phhs-24thiaz-bala-betahmo 45 3745: tolhs-24thiaz-bala-csdap
3746 : bhs-26py-gly-betapy3746: bhs-26py-gly-betapy
3747: bim-53pyrazo-leu-betapy 3748: 2py-25methiaz-gly-zdap3747: bim-53pyrazo-leu-betapy 3748: 2py-25methiaz-gly-zdap
3749: ibhs-nme35pyr-gly-betadtrif3749: ibhs-nme35pyr-gly-betadtrif
3750: dhim-42pym-ala-betadcph3750: dhim-42pym-ala-betadcph
3751: ibhs-nme35pyr-ba1a-zdaptb 5 3752: bim-25thiaz-gly-betadbph3751: ibhs-nme35pyr-ba1a-zdaptb 5 3752: bim-25thiaz-gly-betadbph
3753: tolhs-25oxaz-bala-betahmph3753: tolhs-25oxaz-bala-betahmph
3754: tolhs-25methiaz-bala-betahph3754: tolhs-25methiaz-bala-betahph
3755: ibhs-ithiadiaz-gly-betapyr3755: ibhs-ithiadiaz-gly-betapyr
3756: bhs-ithiadiaz-ala-betaipro3756: bhs-ithiadiaz-ala-betaipro
3757: ibhs-25methiaz-bala-psdapch3757: ibhs-25methiaz-bala-psdapch
10 3758: phhs-nme35pyr-bala-zdapee10 3758: phhs-nme35pyr-bala-zdapee
3759 : bim-me25thiaz-bala-beta34meoph3759: bim-me25thiaz-bala-beta34meoph
3760 : tolhs-oxadiaz-bala-betahdcph3760: tolhs-oxadiaz-bala-betahdcph
3761: phhs-oxadiaz-gly-betampy3761: phhs-oxadiaz-gly-betampy
3762 : ibhs-oxadiaz-gly-betathiome 15 3763: impy-2thioph-gly-betapy3762: ibhs-oxadiaz-gly-betathiome 15 3763: impy-2thioph-gly-betapy
3764: bhs-25oxaz-gly-betainyl3764: bhs-25oxaz-gly-betainyl
3765: ibhs-25thiaz-bala-betafph3765: ibhs-25thiaz-bala-betafph
3766: tolhs-ithiadiaz-gly-betafphe3766: tolhs-ithiadiaz-gly-betafphe
3767: hts-42pym-gly-betapy 20 3768: ibhs-24thiaz-gly-betahmph3767: hts-42pym-gly-betapy 20 3768: ibhs-24thiaz-gly-betahmph
3769: phhs-nme35pyr-bala-betapyee3769: phhs-nme35pyr-bala-betapyee
3770: tolhs-nme35pyr-gly-beta34meoph3770: tolhs-nme35pyr-gly-beta34meoph
3771: bim-me25thioph-bala-betaph3771: bim-me25thioph-bala-betaph
3772: tolhs-24thiaz-bala-betadmph3772: tolhs-24thiaz-bala-betadmph
3773: bhs-ithiadiaz-gly-betaamibe3773: bhs-ithiadiaz-gly-betaamibe
25 3774: bhs-25thioph-leu-psdap25 3774: bhs-25thioph-leu-psdap
3775: bhs-me25thiaz-leu-betaph3775: bhs-me25thiaz-leu-betaph
3776: bhs-25methiaz-bala-csdap3776: bhs-25methiaz-bala-csdap
3777: tolhs-25thiaz-gly-beta4bph3777: tolhs-25thiaz-gly-beta4bph
3778: bhs-24thioph-nmgly-betainyl 30 3779: phhs-oxadiaz-gly-betabenfu3778: bhs-24thioph-nmgly-betainyl 30 3779: phhs-oxadiaz-gly-betabenfu
3780: phhs-nme35pyr-gly-psdaptb3780: phhs-nme35pyr-gly-psdaptb
3781: gua-24thiaz-gly-betatos3781: gua-24thiaz-gly-betatos
3782 : tolhs-oxadiaz-gly-betabdimo3782: tolhs-oxadiaz-gly-betabdimo
3783: bhs-25thiaz-gly-betafluo 35 3784: bhs-triaz-ala-psdap3783: bhs-25thiaz-gly-betafluo 35 3784: bhs-triaz-ala-psdap
3785: bhs-35pyrazo-gly-betapy3785: bhs-35pyrazo-gly-betapy
3786: 2pmhs-24thiaz-bala-betapyr3786: 2 pmhs-24thiaz-bala-betapyr
3787 : tolhs-25methiaz-bala-betaphethioa3787: tolhs-25methiaz-bala-betaphethioa
3788: bhs-24thiaz-bala-betahdbph3788: bhs-24thiaz-bala-betahdbph
3789: ibhs-25thiaz-gly-betadcphee3789: ibhs-25thiaz-gly-betadcphee
40 3790 : phhs-24thioph-bala-betadito40 3790: phhs-24thioph-bala-betadito
3791: phhs-oxadiaz-gly-betabdimo3791: phhs-oxadiaz-gly-betabdimo
3792: 2py-24thiazme-gly-betapy3792: 2py-24thiazme-gly-betapy
3793 : ibhs-nme35pyr-gly-beta34meoph3793: ibhs-nme35pyr-gly-beta34meoph
3794: phhs-ithiadiaz-gly-betahbcph 45 3795: ibhs-oxadiaz-gly-betaibph3794: phhs-ithiadiaz-gly-betaahph 45 3795: ibhs-oxadiaz-gly-betaibph
3796: 2py-24thioph-bala-psdap3796: 2py-24thioph-bala-psdap
3797: 2pmhs-25oxaz-bala-suabu 3798: bhs-24thioph-nmgly-betabpy3797: 2 pmhs-25oxaz-bala-suabu 3798: bhs-24thioph-nmgly-betabpy
3799: ibhs-oxadiaz-bala-asppha3799: ibhs-oxadiaz-bala-asppha
3800 : gua-25thiaz-gly-betaomebendi3800: gua-25thiaz-gly-betaomebendi
3801: 3pmhs-42pym-gly-betapy 5 3802: tolhs-25thiaz-gly-suabu3801: 3 pmhs-42pym-gly-betapy 5 3802: tolhs-25thiaz-gly-suabu
3803: ibhs-24thioph-bala-betafu23803: ibhs-24thioph-bala-betafu2
3804: tolhs-oxadiaz-bala-psdapch3804: tolhs-oxadiaz-bala-psdapch
3805 : ibhs-oxadiaz-bala-betadcphtb3805: ibhs-oxadiaz-bala-betadcphtb
3806 : phhs-ithiadiaz-bala-betaftrif3806: phhs-ithiadiaz-bala-betaftrif
3807: ibhs-oxadiaz-gly-betaoxope3807: ibhs-oxadiaz-gly-betaoxope
10 3808: 2py-oxadiaz-bala-psdap10 3808: 2py-oxadiaz-bala-psdap
3809: tolhs-me25oxaz-gly-psdap3809: tolhs-me25oxaz-gly-psdap
3810 : bhs-25methiaz-nmgly-betal3bendi3810: bhs-25methiaz-nmgly-betal3bendi
3811: tolhs-24thiaz-bala-betabpy3811: tolhs-24thiaz-bala-betabpy
3812: hs-42pym-gly-betapy 15 3813: tolhs-25oxaz-bala-betapbiph3812: hs-42pym-gly-betapy 15 3813: tolhs-25oxaz-bala-betapbiph
3814 : ibhs-oxadiaz-bala-beta34meoph3814: ibhs-oxadiaz-bala-beta34meoph
3815: bhs-ithiadiaz-ala-betameph3815: bhs-ithiadiaz-ala-betameph
3816: phhs-me24oxaz-leu-beta34meoph3816: phhs-me24oxaz-leu-beta34meoph
3817: bhs-25thiaz-nmgly-betafphe 20 3818: tolhs-ithiadiaz-gly-betafluo3817: bhs-25thiaz-nmgly-betafphe 20 3818: tolhs-ithiadiaz-gly-betafluo
3819: tolhs-25thiaz-bala-betamethi3819: tolhs-25thiaz-bala-betamethi
3820: bhs-24thioph-nmgly-betathio33820: bhs-24thioph-nmgly-betathio3
3821: bhs-24thiaz-hphe-betapy3821: bhs-24thiaz-hphe-betapy
3822 : tolhs-25methiaz-bala-aspbzla3822: tolhs-25methiaz-bala-aspbzla
3823: bim-me25thiaz-ala-betadcph3823: bim-me25thiaz-ala-betadcph
25 3824: bhs-25thiaz-bala-asppha25 3824: bras-25thiaz-bala-asppha
3825: bhs-nme35pyr-gly-betamesu3825: bhs-nme35pyr-gly-betamesu
3826: ibhs-ithiadiaz-gly-betapyee3826: ibhs-ithiadiaz-gly-betapyee
3827 : phhs-25oxaz-bala-betabnaphth3827: phhs-25oxaz-bala-betabnaphth
3828: ibhs-24thioph-gly-betadmoph 30 3829: phhs-ithiadiaz-gly-betabnaphth3828: ibhs-24thioph-gly-betadmoph 30 3829: phhs-ithiadiaz-gly-betabnaphth
3830: tolhs-nme35pyr-gly-beta3quin3830: tolhs-nme35pyr-gly-beta3quin
3831: bhs-me25thioph-bala-betapy3831: bhs-me25thioph-bala-betapy
3832: tolhs-nme35pyr-bala-betapym3832: tolhs-nme35pyr-bala-betapym
3833: bhs-nme35pyr-ala-beta3quin 35 3834: ibhs-25oxaz-gly-betarnethioph3833: bhs-nme35pyr-ala-beta3quin 35 3834: ibhs-25oxaz-gly-betarnethioph
3835: tolhs-25thiaz-gly-betaoxaz3835: tolhs-25thiaz-gly-betaoxaz
3836 : phhs-ithiadiaz-bala-betadcphee3836: phhs-ithiadiaz-bala-betadcphee
3837 : tolhs-24thiaz-bala-betaphethioa3837: tolhs-24thiaz-bala-betaphethioa
3838: 2py-25oxaz-gly-betadcph3838: 2py-25oxaz-gly-betadcph
3839: tolhs-oxadiaz-bala-betampy3839: tolhs-oxadiaz-bala-betampy
40 3840: 2py-42oxaz-leu-betapy40 3840: 2py-42oxaz-leu-betapy
3841: ibhs-24thiaz-gly-zdaptb3841: ibhs-24thiaz-gly-zdaptb
3842 : phhs-ithiadiaz-bala-psdaptb3842: phhs-ithiadiaz-bala-psdaptb
3843: phhs-nme35pyr-gly-betafluo3843: phhs-nme35pyr-gly-betafluo
3844 : bhs-nme35pyr-gly-zdapee 45 3845: ibhs-24thioph-bala-betaoxaz3844: bhs-nme35pyr-gly-zdapee 45 3845: ibhs-24thioph-bala-betaoxaz
3846: ibhs-24thiaz-bala-betaoxaz3846: ibhs-24thiaz-bala-betaoxaz
3847: thazep-25thiaz-gly-betal3bendi 3848 : bhs-24thioph-ala-betabnaphth3847: thazep-25thiaz-gly-betal3bendi 3848: bhs-24thioph-ala-betabnaphth
3849: bhs-ithiadiaz-nmgly-betamesu3849: bhs-ithiadiaz-nmgly-betamesu
3850: phhs-oxadiaz-gly-betacph3850: phhs-oxadiaz-gly-betacph
3851: ibhs-25methiaz-bala-betapyr 5 3852: 2py-25methiaz-gly-betaol3851: ibhs-25methiaz-bala-betapyr 5 3852: 2py-25methiaz-gly-betaol
3853 : tolhs-25methiaz-gly-betahbcph3853: tolhs-25methiaz-gly-betahbcph
3854: ibhs-25thiaz-bala-betadmph3854: ibhs-25thiaz-bala-betadmph
3855: phhs-25thiaz-gly-beta35dbph3855: phhs-25thiaz-gly-beta35dbph
3856: ibhs-25thiaz-gly-csdap3856: ibhs-25thiaz-gly-csdap
3857 : phhs-25thiaz-gly-betamethioph3857: phhs-25thiaz-gly-betamethioph
10 3858: 2py-24thiaz-gly-betathio310 3858: 2py-24thiaz-gly-betathio3
3859: ibhs-ithiadiaz-bala-betahni3859: ibhs-ithiadiaz-bala-betahni
3860: gua-25thioph-gly-betathio33860: gua-25thioph-gly-betathio3
3861: bhs-oxadiaz-gly-beta34dcph3861: bhs-oxadiaz-gly-beta34dcph
3862: dhim-25thiophme-ala-betameph 15 3863: ibhs-nme35pyr-bala-betahdcph3862: dhim-25thiophme-ala-betameph 15 3863: ibhs-nme35pyr-bala-betahdcph
3864 : tolhs-nme35pyr-bala-betathio33864: tolhs-nme35pyr-bala-betathio3
3865 : bhs-24thioph-gly-betacthioph3865: bhs-24thioph-gly-betacthioph
3866: phhs-25thiaz-bala-betaol3866: phhs-25thiaz-bala-betaol
3867: ibhs-24thiaz-gly-ibsdap 20 3868: bhs-me24im-gly-betameph3867: ibhs-24thiaz-gly-ibsdap 20 3868: bhs-me24im-gly-betameph
3869 : tolhs-24thiaz-gly-betabnaphth3869: tolhs-24thiaz-gly-betabnaphth
3870: tolhs-me25thiaz-bala-zdap3870: tolhs-me25thiaz-bala-zdap
3871: 2py-35fur-bala-zdap3871: 2py-35fur-bala-zdap
3872 : tolhs-oxadiaz-bala-betabthioph3872: tolhs-oxadiaz-bala-betabthioph
3873: bhs-ithiadiaz-gly-betahph3873: bhs-ithiadiaz-gly-betahph
25 3874: bgua-25methiaz-gly-betameph25 3874: bgua-25methiaz-gly-betameph
3875 : phhs-ithiadiaz-bala-betabediox3875: phhs-ithiadiaz-bala-betabediox
3876 : phhs-25methiaz-bala-betadcph3876: phhs-25methiaz-bala-betadcph
3877: ibhs-nme35pyr-gly-betapbiph3877: ibhs-nme35pyr-gly-betapbiph
3878: tolhs-25methiaz-gly-betabenfu 30 3879: bim-25thiaz-bala-psdap3878: tolhs-25methiaz-gly-betabenfu 30 3879: bim-25thiaz-bala-psdap
3880: bhs-25methiaz-gly-betaet3880: bhs-25methiaz-gly-betaet
3881: phhs-me25thioph-bala-psdap3881: phhs-me25thioph-bala-psdap
3882 : tolhs-25thiaz-gly-betaoxope3882: tolhs-25thiaz-gly-betaoxope
3883 : tolhs-ithiadiaz-gly-betafu2 35 3884: ibhs-oxadiaz-bala-betabpy3883: tolhs-ithiadiaz-gly-betafu2 35 3884: ibhs-oxadiaz-bala-betabpy
3885: bim-25methiaz-gly-aspaba3885: bim-25methiaz-gly-aspaba
3886: ibhs-nme35pyr-bala-betaamibe3886: ibhs-nme35pyr-bala-betaamibe
3887 : bhs-25methiaz-bala-betainyl3887: bhs-25methiaz-bala-betainyl
3888: bhs-ithiadiaz-gly-psdapee3888: bhs-ithiadiaz-gly-psdapee
3889: bgua-25oxaz-bala-betapy3889: bgua-25oxaz-bala-betapy
40 3890: phhs-25methiaz-gly-betamesu40 3890: phhs-25methiaz-gly-betamesu
3891 : phhs-25methiaz-bala-betaftrif3891: phhs-25methiaz-bala-betaftrif
3892 : ibhs-25thiaz-bala-betaanaphth3892: ibhs-25thiaz-bala-betaanaphth
3893: ibhs-oxadiaz-bala-beta3quin3893: ibhs-oxadiaz-bala-beta3quin
3894: phhs-25methiaz-bala-zdapch 45 3895: phhs-nme35pyr-bala-ibsdap3894: phhs-25methiaz-bala-zdapch 45 3895: phhs-nme35pyr-bala-ibsdap
3896 : 2pmhs-25methiaz-bala-betathioph3896: 2 pmhs-25methiaz-bala-betathioph
3897: bhs-me24thiaz-leu-betapy 3898: phhs-25thiaz-bala-betathiome 3899 : tolhs-25thiaz-gly-betapbiph3897: bhs-me24thiaz-leu-betapy 3898: phhs-25thiaz-bala-betathiome 3899: tolhs-25thiaz-gly-betapbiph
3900: gua-25thioph-gly-betahmo3900: gua-25thioph-gly-betahmo
3901: bim-25thioph-bala-betapy 5 3902: tolhs-oxadiaz-bala-beta35dbph3901: bim-25thioph-bala-betapy 5 3902: tolhs-oxadiaz-bala-beta35dbph
3903 : tolhs-ithiadiaz-gly-aspbzla3903: tolhs-ithiadiaz-gly-aspbzla
3904: tolhs-nme35pyr-bala-betacthioph3904: tolhs-nme35pyr-bala-betacthioph
3905: bhs-triaz-gly-psdap3905: bhs-triaz-gly-psdap
3906: ibhs-oxadiaz-bala-betadhbfu3906: ibhs-oxadiaz-bala-betadhbfu
3907: phhs-me25oxaz-leu-zdap3907: phhs-me25oxaz-leu-zdap
1010
3908 : tolhs-oxadiaz-gly-betamethioph3908: tolhs-oxadiaz-gly-betamethioph
3909: bhs-25oxaz-bala-betadbph3909: bras-25oxaz-bala-betadbph
3910: bhs-oxadiaz-bala-betameph3910: bras-oxadiaz-bala-betameph
3911: phhs-24thiaz-gly-aspaba3911: phhs-24thiaz-gly-aspaba
3912: bim-25thiaz-bala-betaimid 15 3913: 2py-24thioph-leu-betadcph3912: bim-25thiaz-bala-betaimid 15 3913: 2py-24thioph-leu-betadcph
3914 : ibhs-25oxaz-gly-betaanaphth3914: ibhs-25oxaz-gly-betaanaphth
3915: ibhs-nme35pyr-gly-betapyr3915: ibhs-nme35pyr-gly-betapyr
3916 : tolhs-24thioph-gly-beta35dbph3916: tolhs-24thioph-gly-beta35dbph
3917 : 2pmhs-25methiaz-bala-betapyr 20 3918: tolhs-25thiaz-gly-betadmph3917: 2 pmhs-25methiaz-bala-betapyr 20 3918: tolhs-25thiaz-gly-betadmph
3919: 2py-25methiaz-leu-betapy3919: 2py-25methiaz-leu-betapy
3920: bhs-oxadiaz-bala-asppha3920: bras-oxadiaz-bala-asppha
3921: bhs-25oxaz-gly-betahb3921: bras-25oxaz-gly-betahb
3922 : tolhs-24thioph-bala-betameph3922: tolhs-24thioph-bala-betameph
3923 : phhs-me25oxaz-leu-beta34meoph3923: phhs-me25oxaz-leu-beta34meoph
25 3924: 2py-42nmeim-bala-betapy25 3924: 2py-42nmeim-bala-betapy
3925: phhs-me25thiaz-ala-betapy3925: phhs-me25thiaz-ala-betapy
3926: phhs-25methiaz-bala-betampy3926: phhs-25methiaz-bala-betampy
3927: ibhs-25oxaz-bala-suabu3927: ibhs-25oxaz-bala-suabu
3928: bhs-oxadiaz-gly-betabmph 30 3929: bhs-25oxaz-bala-betambiph3928: bhs-oxadiaz-gly-betabmph 30 3929: bhs-25oxaz-bala-betambiph
3930: tolhs-nme35pyr-gly-aspbzla3930: tolhs-nme35pyr-gly-aspbzla
3931: ibhs-nme35pyr-gly-betapych3931: ibhs-nme35pyr-gly-betapych
3932: ibhs-24thiaz-gly-betaph3932: ibhs-24thiaz-gly-betaph
3933 : bhs-24thiaz-bala-betacthioph 35 3934: bhs-me25oxaz-leu-beta34meoph3933: bhs-24thiaz-bala-betacthioph 35 3934: bhs-me25oxaz-leu-beta34meoph
3935: bhs-25oxaz-bala-betahbcph3935: bras-25oxaz-bala-betahbcph
3936: tolhs-25oxaz-bala-betafbph3936: tolhs-25oxaz-bala-betafbph
3937 : tolhs-25methiaz-bala-betabmph3937: tolhs-25methiaz-bala-betabmph
3938: bhs-nme35pyr-nmgly-betadhbfu3938: bhs-nme35pyr-nmgly-betadhbfu
3939: phhs-25methiaz-bala-betahni3939: phhs-25methiaz-bala-betahni
40 3940 : bhs-24thioph-bala-beta34meoph40 3940: bhs-24thioph-bala-beta34meoph
3941: 2py-24thioph-gly-betadito3941: 2py-24thioph-gly-betadito
3942: bhs-25oxaz-gly-betahph3942: bhs-25oxaz-gly-betahph
3943: bhs-25methiaz-gly-psdaptb3943: bhs-25methiaz-gly-psdaptb
3944: ibhs-nme35pyr-gly-betapym 45 3945: ibhs-ithiadiaz-gly-betadmph3944: ibhs-nme35pyr-gly-betapym 45 3945: ibhs-ithiadiaz-gly-betadmph
3946: bim-24im-leu-zdap3946: bim-24im-leu-zdap
3947 : impy-25thiaz-gly-beta34meoph 3948: ur-42pym-ala-psdap 3949: bhs-ithiadiaz-bala-betafbph 3950: bhs-24thiaz-gly-betatos 3951: ibhs-24thioph-gly-zdapee 5 3952: tolhs-25methiaz-bala-betadcphtb 3953: ibhs-ithiadiaz-bala-betahmo 3954: ibhs-nme35pyr-bala-betahb 3955: phhs-25oxaz-gly-betaet3947: impy-25thiaz-gly-beta34meoph 3948: ur-42pym-ala-psdap 3949: bhs-ithiadiaz-bala-betafbph 3950: bhs-24thiaz-gly-betatos 3951: ibhs-24thioph-gly-zdapee 5 3952: tolhs-25methiaz-bala-betadcphtb 3953: ibhs- ithiadiaz-bala-betahmo 3954: ibhs-nme35pyr-bala-betahb 3955: phhs-25oxaz-gly-betaet
3956: ibhs-24thiaz-gly-betathio33956: ibhs-24thiaz-gly-betathio3
3957: bhs-25methiaz-gly-betahmph3957: bhs-25methiaz-gly-betahmph
10 3958: bhs-42oxaz-ala-psdap10 3958: bhs-42oxaz-ala-psdap
3959: gua-25thiaz-gly-betapy3959: gua-25thiaz-gly-betapy
3960: ibhs-nme35pyr-bala-betahbcph3960: ibhs-nme35pyr-bala-betahbcph
3961: phhs-nme35pyr-bala-betathiome3961: phhs-nme35pyr-bala-betathiome
3962: bim-25methiaz-bala-psdap 15 3963: bhs-24thiaz-ala-betadmph3962: bim-25methiaz-bala-psdap 15 3963: bhs-24thiaz-ala-betadmph
3964 : phhs-25methiaz-gly-betathiome3964: phhs-25methiaz-gly-betathiome
3965 : phhs-me25thioph-bala-betadcph3965: phhs-me25thioph-bala-betadcph
3966 : bhs-ithiadiaz-bala-betathiome3966: bhs-ithiadiaz-bala-betathiome
3967 : bhs-nme35pyr-bala-betathioph 2o 3968: bim-24thioph-bala-betaimid3967: bhs-nme35pyr-bala-betathioph 2o 3968: bim-24thioph-bala-betaimid
3969 : phhs-24thioph-gly-betaftrif3969: phhs-24thioph-gly-betaftrif
3970: bhs-25thiaz-gly-betadcph3970: bhs-25thiaz-gly-betadcph
3971: phhs-me25thioph-gly-betaph3971: phhs-me25thioph-gly-betaph
3972: bim-25methiaz-ala-betapy3972: bim-25methiaz-ala-betapy
3973: bhs-24thioph-ala-betathio33973: bhs-24thioph-ala-betathio3
25 3974: ibhs-24thiaz-bala-aspbzla25 3974: ibhs-24thiaz-bala-aspbzla
3975: phhs-oxadiaz-bala-betahmph3975: phhs-oxadiaz-bala-betahmph
3976 : bhs-ithiadiaz-ala-betaanaphth3976: bhs-ithiadiaz-ala-betaanaphth
3977: bhs-25oxaz-gly-aspaba3977: bras-25oxaz-gly-aspaba
3978: bhs-ithiadiaz-gly-betaol 30 3979: 2py-thiadiaz-leu-betadcph3978: bhs-ithiadiaz-gly-betaol 30 3979: 2py-thiadiaz-leu-betadcph
3980: ph.hs-rr.e25oxaz-bala-betapy3980: ph.hs-rr.e25oxaz-bala-betapy
3981: ibhs-25oxaz-gly-beta34dcph3981: ibhs-25oxaz-gly-beta34dcph
3982: ibhs-oxadiaz-gly-betabmph3982: ibhs-oxadiaz-gly-betabmph
3983: bhs-oxadiaz-bala-beta4bph 35 3984: tolhs-24thiaz-bala-betafu33983: bhs-oxadiaz-bala-beta4bph 35 3984: tolhs-24thiaz-bala-betafu3
3985: bhs-25oxaz-bala-betafu23985: bras-25oxaz-bala-betafu2
3986: tolhs-me25thiaz-ala-psdap3986: tolhs-me25thiaz-ala-psdap
3987: tolhs-25oxaz-bala-betamesu3987: tolhs-25oxaz-bala-betamesu
3988: 2py-26py-gly-betahdcph3988: 2py-26py-gly-betahdcph
3989: bhs-25methiaz-met-betadcph3989: bras-25methiaz-met-betadcph
40 3990 : bhs-me25oxaz-bala-beta34meoph40 3990: bhs-me25oxaz-bala-beta34meoph
3991: bim-me24thioph-gly-betaph3991: bim-me24thioph-gly-betaph
3992: bhs-25oxaz-gly-betaibph3992: bhs-25oxaz-gly-betaibph
3993: phhs-oxadiaz-gly-betahdbph3993: phhs-oxadiaz-gly-betahdbph
3994: tolhs-me25oxaz-ala-betadcph 45 3995: 2py-25fur-gly-zdap3994: tolhs-me25oxaz-ala-betadcph 45 3995: 2py-25fur-gly-zdap
3996: bim-thiadiaz-leu-betapy3996: bim-thiadiaz-leu-betapy
3997 : tolhs-24thiaz-bala-betathioph 3998: 2py-24thioph-gly-betathio3 3999: bhs-24thiaz-gly-betahmo 4000: phhs-nme35pyr-gly-betabenfu 4001: ibhs-25thiaz-bala-betapych 5 4002: bhs-24oxaz-ala-zdap3997: tolhs-24thiaz-bala-betathioph 3998: 2py-24thioph-gly-betathio3 3999: bhs-24thiaz-gly-betahmo 4000: phhs-nme35pyr-gly-betabenfu 4001: ibhs-25thiaz-bala-betapych 5 4002: bhs-24oxaz-ala-zdap
4003: impy-24thiaz-bala-betamethi4003: impy-24thiaz-bala-betamethi
4004 : ibhs-oxadiaz-gly-betaphethio4004: ibhs-oxadiaz-gly-betaphethio
4005: tolhs-25thiaz-bala-betaet4005: tolhs-25thiaz-bala-betet
4006: phhs-25methiaz-bala-betahmph4006: phhs-25methiaz-bala-betahmph
4007: phhs-oxadiaz-bala-betadito4007: phhs-oxadiaz-bala-betadito
10 4008: bim-25fur-ala-betadcph10 4008: bim-25fur-ala-betadcph
4009 : tolhs-oxadiaz-bala-beta34meoph4009: tolhs-oxadiaz-bala-beta34meoph
4010: bhs-24thioph-ala-betamesu4010: bhs-24thioph-ala-betamesu
4011: phhs-25thiaz-gly-betadmoph4011: phhs-25thiaz-gly-betadmoph
4012: bhs-nme35pyr-ala-betaipro 15 4013: tolhs-25thiaz-gly-betabpy4012: bhs-nme35pyr-ala-betaipro 15 4013: tolhs-25thiaz-gly-betabpy
4014: ibhs-nme35pyr-gly-betaipr4014: ibhs-nme35pyr-gly-betaipr
4015: bhs-25methiaz-gly-betabmph4015: bhs-25methiaz-gly-betabmph
4016: tolhs-25oxaz-bala-betapych4016: tolhs-25oxaz-bala-betapych
4017: tolhs-oxadiaz-gly-csdap 20 4018: tolhs-nme35pyr-bala-beta35dbph4017: tolhs-oxadiaz-gly-csdap 20 4018: tolhs-nme35pyr-bala-beta35dbph
4019 : 2py-me25thioph-leu-beta34meoph4019: 2py-me25thioph-leu-beta34meoph
4020: phhs-oxadiaz-bala-betahni4020: phhs-oxadiaz-bala-betahni
4021: ibhs-24thioph-bala-betadmph4021: ibhs-24thioph-bala-betadmph
4022: bhs-25methiaz-gly-betadito4022: bhs-25methiaz-gly-betadito
4023 : bhs-42nmeim-ala-betadcph4023: bhs-42nmeim-ala-betadcph
2525
4024 : ibhs-25oxaz-bala-betaphethioa4024: ibhs-25oxaz-bala-betaphethioa
4025: bim-me24thiaz-bala-zdap4025: bim-me24thiaz-bala-zdap
4026: bhs-42py-gly-betameph4026: bhs-42py-gly-betameph
4027: tolhs-24thioph-gly-betahmph4027: tolhs-24thioph-gly-betahmph
4028: bim-me24thioph-ala-zdap 30 4029: bim-me25thiaz-gly-beta34meoph4028: bim-me24thioph-ala-zdap 30 4029: bim-me25thiaz-gly-beta34meoph
4030: bhs-25thiaz-bala-betabthioph4030: bhs-25thiaz-bala-betabthioph
4031: bim-25thiaz-gly-aspaba4031: bim-25thiaz-gly-aspaba
4032 : gua-24thiaz-gly-betafbph4032: gua-24thiaz-gly-betafbph
4033 : thpym-42pym-gly-betahcbph 35 4034: bhs-nme35pyr-bala-betaamibe4033: thpym-42pym-gly-betahcbph 35 4034: bhs-nme35pyr-bala-betaamibe
4035: bhs-25oxaz-gly-betapbiph4035: bhs-25oxaz-gly-betapbiph
4036: phhs-25thiaz-gly-betahc4036: phhs-25thiaz-gly-betahc
4037: 2py-nme35pyr-bala-aspibua4037: 2py-nme35pyr-bala-aspibua
4038: bim-24oxaz-gly-betadcph4038: bim-24oxaz-gly-betadcph
4039: phhs-24thioph-gly-betahbcph4039: phhs-24thioph-gly-betahbcph
40 4040: 2py-me25thioph-leu-betapy40 4040: 2py-me25thioph-leu-betapy
4041: bhs-me25thioph-ala-psdap4041: bhs-me25thioph-ala-psdap
4042: bhs-me25oxaz-leu-betapy4042: bhs-me25oxaz-leu-betapy
4043 : tolhs-ithiadiaz-bala-betahmofu4043: tolhs-ithiadiaz-bala-betahmofu
4044 : 2py-25thiaz-bala-betabnaphth 45 4045: bim-24thiaz-gly-betadmph4044: 2py-25thiaz-bala-betabnaphth 45 4045: bim-24thiaz-gly-betadmph
4046: ibhs-24thiaz-gly-betaol4046: ibhs-24thiaz-gly-betaol
4047: tolhs-25thiaz-gly-betafbph 4048: bhs-42nmeim-bala-betapy 4049: phhs-25methiaz-gly-betahb 4050: phhs-25thiaz-bala-betacbph 4051: tolhs-nme35pyr-gly-zdapee 4052: phhs-ithiadiaz-bala-zdaptb 4053: thazep-25thiaz-bala-zdap 4054: 2py-24chin-gly-betapy 4055: ibhs-25methiaz-gly-betapytb 4056 : bhs-25thiaz-bala-betadcphtb 4057 : phhs-25methiaz-bala-betal3bendi4047: tolhs-25thiaz-gly-betafbph 4048: bhs-42nmeim-bala-betapy 4049: phhs-25methiaz-gly-betahb 4050: phhs-25thiaz-bala-betacbph 4051: tolhs-nme35pyr-gly-zdapee 4052: phhs-ithiadiaz-bala-zdaptb 4053: thazep -bala-zdap 4054: 2py-24chin-gly-betapy 4055: ibhs-25methiaz-gly-betapytb 4056: bhs-25thiaz-bala-betadcphtb 4057: phhs-25methiaz-bala-betal3bendi
10 4058 : tolhs-24thiaz-gly-betapbiph 4059: bhs-ithiadiaz-gly-betaipr 4060: 2py-35thioph-gly-zdap 4061: phhs-me25thiaz-gly-zdap 4062 : ibhs-24thioph-bala-betadcph10 4058: tolhs-24thiaz-gly-betapbiph 4059: bhs-ithiadiaz-gly-betaipr 4060: 2py-35thioph-gly-zdap 4061: phhs-me25thiaz-gly-zdap 4062: ibhs-24thioph-bala-betadcph
15 4063: tolhs-25oxaz-gly-betambiph 4064 : bhs-nme35pyr-gly-betahmph 4065: bhs-25methiaz-ala-psdap 4066: tolhs-25thiaz-bala-betafph 4067 : tolhs-ithiadiaz-gly-betabph15 4063: tolhs-25oxaz-gly-betambiph 4064: bhs-nme35pyr-gly-betahmph 4065: bhs-25methiaz-ala-psdap 4066: tolhs-25thiaz-bala-betafph 4067: tolhs-ithiadiaz-gly-betabph
20 4068: tolhs-nme35pyr-bala-aspaba 4069: 2py-42oxaz-ala-zdap 4070 : ibhs-nme35pyr-bala-betadcphch 4071: 2py-24thiaz-ala-betameph 4072: 2py-24thiaz-gly-betaol 4073 : ibhs-25methiaz-bala-betapych20 4068: tolhs-nme35pyr-bala-aspaba 4069: 2py-42oxaz-ala-zdap 4070: ibhs-nme35pyr-bala-betadcphch 4071: 2py-24thiaz-ala-betameph 4072: 2py-24thiaz-gly-betaol 4073: ibhs- 25methiaz-bala-betapych
25 4074: 2pmhs-24thiaz-gly-betadtrif 4075: dhim-26pyrazi-gly-betameph 4076: tolhs-24thiaz-gly-betadcph 4077: ibhs-nme35pyr-bala-betapym 4078: ibhs-25methiaz-bala-betahb25 4074: 2 pmhs-24thiaz-gly-betadtrif 4075: dhim-26pyrazi-gly-betameph 4076: tolhs-24thiaz-gly-betadcph 4077: ibhs-nme35pyr-bala-betapym 4078: ibhs-25methiaz-bala-betahb
30 4079: bhs-24thioph-bala-betadcph 4080: ibhs-oxadiaz-gly-betapyee 4081: bhs-25thiaz-gly-aspibua 4082: bim-me25thiaz-leu-betadcph 4083 : phhs-25methiaz-bala-betatos30 4079: bhs-24thioph-bala-betadcph 4080: ibhs-oxadiaz-gly-betapyee 4081: bhs-25thiaz-gly-aspibua 4082: bim-me25thiaz-leu-betadcph 4083: phhs-25methiaz-bala-betatos
35 4084: phhs-me25thiaz-ala-psdap 4085: bhs-25methiaz-ala-ibsdap 4086: bim-52thiaz-ala-betadcph 4087: phhs-24thiaz-bala-betambiph 4088: phhs-ithiadiaz-gly-beta3quin 4089: bhs-24thioph-gly-betapbiph35 4084: phhs-me25thiaz-ala-psdap 4085: bhs-25methiaz-ala-ibsdap 4086: bim-52thiaz-ala-betadcph 4087: phhs-24thiaz-bala-betambiph 4088: phhs-ithiadiaz-gly-beta3quin 4089: bhs- 24thioph-gly-betapbiph
40 4090: 2py-25oxaz-bala-betaftrif 4091: bhs-oxadiaz-ala-betameph 4092 : tolhs-oxadiaz-bala-betaoxaz 4093: ibhs-oxadiaz-bala-betaibph 4094: bhs-24thiaz-gly-betaph40 4090: 2py-25oxaz-bala-betaftrif 4091: bhs-oxadiaz-ala-betameph 4092: tolhs-oxadiaz-bala-betaoxaz 4093: ibhs-oxadiaz-bala-betaibph 4094: bhs-24thiaz-gly-betaph
45 4095: ibhs-nme35pyr-gly-betafbph45 4095: ibhs-nme35pyr-gly-betafbph
4096 : tolhs-nme35pyr-gly-betaanaphth 4097: phhs-24thiaz-gly-betamesu 4098: bhs-25oxaz-ala-betadcph 4099 : tolhs-ithiadiaz-bala-betaimid 4100: impy-25oxaz-gly-betabph 4101: dhim-42pym-gly-betadtrif 4102: 2py-me25thioph-bala-betapy 4103 : ibhs-24thioph-gly-betadtrif 4104 : 2py-me24thioph-bala-beta34meoph 4105: bhs-25thiaz-nmgly-ibsdap 4106: phhs-nme35pyr-bala-betahmo 4107: phhs-25oxaz-gly-betaheph4096: tolhs-nme35pyr-gly-betaanaphth 4097: phhs-24thiaz-gly-betamesu 4098: bhs-25oxaz-ala-betadcph 4099: tolhs-ithiadiaz-bala-betaimid 4100: impy-25oxaz-gly-betabph 4101: dhim-42pym-gly-betadtrif 4102: 2py-me25thioph-bala-betapy 4103: ibhs-24thioph -gly-betadtrif 4104: 2py-me24thioph-bala-beta34meoph 4105: bhs-25thiaz-nmgly-ibsdap 4106: phhs-nme35pyr-bala-betahmo 4107: phhs-25oxaz-gly-betaheph
10 4108: gua-42pym-gly-betainyl 4109: gua-42pym-gly-betaomebendi 4110: bhs-25thiaz-bala-betahbcph 4111: tolhs-25oxaz-bala-betabthioph 4112: bhs-nme35pyr-nmgly-betahmph10 4108: gua-42pym-gly-betainyl 4109: gua-42pym-gly-betaomebendi 4110: bhs-25thiaz-bala-betahbcph 4111: tolhs-25oxaz-bala-betabthioph 4112: bhs-nme35pyr-nmgly-betahmph
15 4113: ibhs-25oxaz-gly-betadmoph 4114: tolhs-nme35pyr-bala-betabmph 4115 : tolhs-nme35pyr-bala-betapbiph 4116: bhs-25oxaz-bala-betahdcph 4117 : impy-24thioph-bala-betamethi15 4113: ibhs-25oxaz-gly-betadmoph 4114: tolhs-nme35pyr-bala-betabmph 4115: tolhs-nme35pyr-bala-betapbiph 4116: bhs-25oxaz-bala-betahdcph 4117: impy-24thiopheth-bala
20 4118: bim-me24oxaz-gly-beta34meoph 4119: phhs-me25oxaz-ala-betapy 4120: bim-me24thioph-gly-psdap 4121: bhs-24thioph-gly-betahph 4122: phhs-24thioph-gly-betaol 4123: ibhs-25thiaz-bala-zdaptb20 4118: bim-me24oxaz-gly-beta34meoph 4119: phhs-me25oxaz-ala-betapy 4120: bim-me24thioph-gly-psdap 4121: bhs-24thioph-gly-betahph 4122: phhs-24thioph-gly-betaol 4123: ibhs- 25thiaz-bala-zdaptb
25 4124: tolhs-nme35pyr-gly-betaamibe 4125: bhs-24thiaz-bala-betahb 4126: bhs-24thiaz-gly-zdapch 4127: gua-42pym-gly-betapyr 4128: phhs-oxadiaz-gly-zdapee25 4124: tolhs-nme35pyr-gly-betaamibe 4125: bhs-24thiaz-bala-betahb 4126: bhs-24thiaz-gly-zdapch 4127: gua-42pym-gly-betapyr 4128: phhs-oxadiaz-gly-zdapee
30 4129: bim-25thiaz-ala-psdap 4130: bhs-ithiadiaz-gly-betapy 4131: bhs-25methiaz-gly-betacph 4132: ibhs-25oxaz-gly-betaet 4133 : 2py-42py-gly-betapy30 4129: bim-25thiaz-ala-psdap 4130: bhs-ithiadiaz-gly-betapy 4131: bhs-25methiaz-gly-betacph 4132: ibhs-25oxaz-gly-betet 4133: 2py-42py-gly-betapy
35 4134: 2py-25oxaz-gly-betapy 4135: bhs-oxadiaz-gly-betafph 4136: ibhs-24thioph-gly-beta3quin 4137 : tolhs-25oxaz-bala-betadcph.ee 4138: 2py-me25oxaz-ala-psdap 4139: bhs-24thioph-nmgly-betadito35 4134: 2py-25oxaz-gly-betapy 4135: bhs-oxadiaz-gly-betafph 4136: ibhs-24thioph-gly-beta3quin 4137: tolhs-25oxaz-bala-betadcph.ee 4138: 2py-me25oxaz-ala-psdap 4139: bhs-24thioph-nmgly-betadito
40 4140 : bhs-nme35pyr-gly-betahdcph 4141: bhs-oxadiaz-bala-betamethi 4142: bhs-nme35pyr-gly-betadcphee 4143 : bhs-25methiaz-bala-betaibph 4144 : bhs-24thioph-bala-beta23meoph40 4140: bhs-nme35pyr-gly-betahdcph 4141: bhs-oxadiaz-bala-betamethi 4142: bhs-nme35pyr-gly-betadcphee 4143: bhs-25methiaz-bala-betaibph 4144: bhs-24thiophoph-bala-beta
45 4145: ibhs-oxadiaz-bala-betatos45 4145: ibhs-oxadiaz-bala-betatos
4146 : tolhs-ithiadiaz-bala-betadtrif 4147: bhs-oxadiaz-gly-betapych 4148 : tolhs-ithiadiaz-bala-betaamibe4146: tolhs-ithiadiaz-bala-betadtrif 4147: bhs-oxadiaz-gly-betapych 4148: tolhs-ithiadiaz-bala-betaamibe
4149: bhs-24thiaz-bala-betadbph4149: bras-24thiaz-bala-betadbph
4150 : bhs-24thioph-bala-betaphethioa4150: bhs-24thioph-bala-betaphethioa
4151 : phhs-25oxaz-bala-betadcphch4151: phhs-25oxaz-bala-betadcphch
5 4152: tolhs-24thiaz-gly-betafluo5,4152: tolhs-24thiaz-gly-betafluo
4153 : phhs-25methiaz-gly-betaimid4153: phhs-25methiaz-gly-betaimide
4154 : tolhs-oxadiaz-gly-betadtrif4154: tolhs-oxadiaz-gly-betadtrif
4155: bhs-nme35pyr-ala-betadmph4155: bhs-nme35pyr-ala-betadmph
4156: bim-25thiaz-bala-betampy4156: bim-25thiaz-bala-betampy
4157 : phhs-25methiaz-bala-betathioph 104157: phhs-25methiaz-bala-betathioph 10
4158: phhs-nme35pyr-gly-zdapch4158: phhs-nme35pyr-gly-zdapch
4159: bhs-25methiaz-gly-betatos4159: bhs-25methiaz-gly-betatos
4160: tolhs-25oxaz-bala-betahc4160: tolhs-25oxaz-bala-betahc
4161 : 2py-me24thiaz-ala-beta34meoph4161: 2py-me24thiaz-ala-beta34meoph
4162 : tolhs-me24thioph-gly-beta34meoph 15 4163: bim-oxadiaz-gly-betadcph4162: tolhs-me24thioph-gly-beta34meoph 15 4163: bim-oxadiaz-gly-betadcph
4164 : ibhs-25thiaz-bala-betapbiph4164: ibhs-25thiaz-bala-betapbiph
4165: bhs-25thiaz-bala-betatos4165: bras-25thiaz-bala-betatos
4166: 2py-25methiaz-bala-betapy4166: 2py-25methiaz-bala-betapy
4167 : tolhs-25methiaz-bala-zdapch 20 4168: gua-42pym-gly-betafluo4167: tolhs-25methiaz-bala-zdapch 20 4168: gua-42pym-gly-betafluo
4169 : bhs-nme35pyr-bala-betaphethioa4169: bhs-nme35pyr-bala-betaphethioa
4170 : tolhs-24thioph-bala-psdapee4170: tolhs-24thioph-bala-psdapee
4171: phhs-25oxaz-gly-ibsdap4171: phhs-25oxaz-gly-ibsdap
4172 : ibhs-25thiaz-gly-betabnaphth4172: ibhs-25thiaz-gly-betabnaphth
4173: 2py-25thiaz-gly-beta35dbph 254173: 2py-25thiaz-gly-beta35dbph 25
4174: ibhs-oxadiaz-gly-betaimid4174: ibhs-oxadiaz-gly-betaimide
4175: bhs-me25thioph-ala-betapy4175: bhs-me25thioph-ala-betapy
4176 : phhs-24thioph-gly-betathioph4176: phhs-24thioph-gly-betathioph
4177 : ibhs-24thiaz-gly-betaomebendi4177: ibhs-24thiaz-gly-betaomebendi
4178: bim-25thiaz-ala-zdap 30 4179: ibhs-25methiaz-bala-betahmph4178: bim-25thiaz-ala-zdap 30 4179: ibhs-25methiaz-bala-betahmph
4180: ibhs-24thioph-gly-betahbcph4180: ibhs-24thioph-gly-betahbcph
4181: bim-25oxaz-gly-betahbcph4181: bim-25oxaz-gly-betahbcph
4182: bhs-ithiadiaz-gly-betadito4182: bhs-ithiadiaz-gly-betadito
4183: bhs-24thioph-nmgly-betaipro 35 4184: bim-35thioph-ala-zdap4183: bhs-24thioph-nmgly-betaipro 35 4184: bim-35thioph-ala-zdap
4185: ibhs-25oxaz-gly-betadcphch4185: ibhs-25oxaz-gly-betadcphch
4186: phhs-24thiaz-bala-zdapee4186: phhs-24thiaz-bala-zdapee
4187: bhs-me24thiaz-bala-betaph4187: bhs-me24thiaz-bala-betaph
4188: bim-nme35pyr-ala-zdap4188: bim-nme35pyr-ala-zdap
4189 : tolhs-25thiaz-gly-betaomebendi4189: tolhs-25thiaz-gly-betaomebendi
4190: bhs-24thioph-gly-psdapee4190: bhs-24thioph-gly-psdapee
4191: tolhs-nme35pyr-bala-zdap4191: tolhs-nme35pyr-bala-zdap
4192: tolhs-nme35pyr-gly-aspaba4192: tolhs-nme35pyr-gly-aspaba
4193 : ibhs-oxadiaz-bala-betatbuph4193: ibhs-oxadiaz-bala-betatbuph
4194: tolhs-25oxaz-gly-betameph 45 4195: 2py-thiadiaz-bala-betadcph4194: tolhs-25oxaz-gly-betameph 45 4195: 2py-thiadiaz-bala-betadcph
4196: bim-24im-gly-betapy4196: bim-24im-gly-betapy
4197 : phhs-24 hioph-gly-betadtrif 4198 : bhs-nme35pyr-bala-betabph4197: phhs-24 hioph-gly-betadtrif 4198: bhs-nme35pyr-bala-betabph
4199: 2py-24thioph-bala-aspibua4199: 2py-24thioph-bala-aspibua
4200 : bhs-25methiaz-bala-betafbph4200: bras-25methiaz-bala-betafbph
4201: bhs-24thiaz-bala-betaibph 5 4202: impy-25thiaz-nmgly-psdap4201: bhs-24thiaz-bala-betaibph 5 4202: impy-25thiaz-nmgly-psdap
4203: phhs-oxadiaz-gly-betatos4203: phhs-oxadiaz-gly-betatos
4204 : phhs-24thioph-gly-betal3bendi4204: phhs-24thioph-gly-betal3bendi
4205: bim-triaz-leu-betadcph4205: bim-triaz-leu-betadcph
4206: phhs-25methiaz-bala-csdap4206: phhs-25methiaz-bala-csdap
4207: phhs-nme35pyr-gly-betainyl4207: phhs-nme35pyr-gly-betainyl
10 4208: ibhs-nme35pyr-bala-beta4bph10 4208: ibhs-nme35pyr-bala-beta4bph
4209: phhs-ithiadiaz-bala-betahni4209: phhs-ithiadiaz-bala-betahni
4210: 2py-24thiaz-ala-psdap4210: 2py-24thiaz-ala-psdap
4211 : tolhs-25thiaz-bala-beta4bph4211: tolhs-25thiaz-bala-beta4bph
4212: bhs-25thiaz-gly-beta34dcph 15 4213: bhs-25thiaz-bala-betafu34212: bhs-25thiaz-gly-beta34dcph 15 4213: bhs-25thiaz-bala-betafu3
4214 : phhs-24thioph-gly-beta35dbph4214: phhs-24thioph-gly-beta35dbph
4215: phhs-24thiaz-gly-betadmoph4215: phhs-24thiaz-gly-betadmoph
4216 : bhs-oxadiaz-ala-betal3bendi4216: bhs-oxadiaz-ala-betal3bendi
4217: 2pmhs-25oxaz-bala-betafluo 2o 4218: phhs-25oxaz-gly-zdaptb4217: 2 pmhs-25oxaz-bala-betafluo 2o 4218: phhs-25oxaz-gly-zdaptb
4219: phhs-24thiaz-bala-betamesu4219: phhs-24thiaz-bala-betamesu
4220: ibhs-24thioph-gly-betaph4220: ibhs-24thioph-gly-betaph
4221: tolhs-nme35pyr-gly-betafphe4221: tolhs-nme35pyr-gly-betafphe
4222 : bhs-25methiaz-gly-betabthioph4222: bhs-25methiaz-gly-betabthioph
4223: bhs-25thiaz-bala-psdap4223: bras-25thiaz-bala-psdap
25 4224: tolhs-25methiaz-gly-betaibph25 4224: tolhs-25methiaz-gly-betaibph
4225: bhs-me25oxaz-leu-betadcph4225: bhs-me25oxaz-leu-betadcph
4226: 2pmhs-25oxaz-bala-beta34dcph4226: 2 pmhs-25oxaz-bala-beta34dcph
4227: 2pmhs-24thiaz-bala-betabmph4227: 2 pmhs-24thiaz-bala-betabmph
4228: bim-2 im-ala-betapy 30 4229: phhs-25thiaz-gly-betathio34228: bim-2 im-ala-betapy 30 4229: phhs-25thiaz-gly-betathio3
4230: ibhs-nme35pyr-gly-betahbcph4230: ibhs-nme35pyr-gly-betahbcph
4231: tolhs-25oxaz-bala-betaol4231: tolhs-25oxaz-bala-betaol
4232: phhs-nme35pyr-bala-zdapch4232: phhs-nme35pyr-bala-zdapch
4233: phhs-24thiaz-gly-betacph 35 4234: ibhs-24thioph-gly-betamethi4233: phhs-24thiaz-gly-betacph 35 4234: ibhs-24thioph-gly-betamethi
4235: 2pmhs-25thiaz-gly-betabpy4235: 2 pmhs-25thiaz-gly-betabpy
4236: phhs-24thioph-bala-zdapee4236: phhs-24thioph-bala-zdapee
4237: phhs-oxadiaz-bala-betapyee4237: phhs-oxadiaz-bala-betapyee
4238: ibhs-24thioph-gly-csdap4238: ibhs-24thioph-gly-csdap
4239: tolhs-oxadiaz-bala-betapyr4239: tolhs-oxadiaz-bala-betapyr
40 4240: bim-25thiaz-bala-aspibua40 4240: bim-25thiaz-bala-aspibua
4241: bhs-oxadiaz-gly-ibsdap4241: bhs-oxadiaz-gly-ibsdap
4242: bim-53pyrazo-leu-betadcph4242: bim-53pyrazo-leu-betadcph
4243: bhs-ithiadiaz-bala-betafu34243: bhs-ithiadiaz-bala-betafu3
4244 : tolhs-ithiadiaz-bala-betambiph 45 4245: ibhs-25methiaz-bala-betabdimo4244: tolhs-ithiadiaz-bala-betambiph 45 4245: ibhs-25methiaz-bala-betabdimo
4246 : impy-25thiaz-gly-betathiobe4246: impy-25thiaz-gly-betathiobe
4247: bhs-oxadiaz-gly-betaanaphth 4248: tolhs-25thiaz-bala-betahdbph4247: bhs-oxadiaz-gly-beta-anaphth 4248: tolhs-25thiaz-bala-betahdbph
4249: bhs-oxadiaz-bala-betathio34249: bras-oxadiaz-bala-betathio3
4250: bhs-25fur-leu-betadcph4250: bras-25fur-leu-betadcph
4251 : 2py-me25thioph-ala-betadcph 5 4252: phhs-24thioph-bala-betamethi4251: 2py-me25thioph-ala-betadcph 5 4252: phhs-24thioph-bala-betamethi
4253: 2pmhs-25oxaz-gly-psdap4253: 2 pmhs-25oxaz-gly-psdap
4254: bhs-oxadiaz-gly-betahmo4254: bras-oxadiaz-gly-betahmo
4255: phhs-nme35pyr-bala-aspbzla4255: phhs-nme35pyr-bala-aspbzla
4256 : nmhs-25thiaz-gly-betadcph4256: nmhs-25thiaz-gly-betadcph
4257: bhs-24thiaz-ala-betadmoph4257: bhs-24thiaz-ala-betadmoph
1010
4258 : impy-25thiaz-bala-psdap4258: impy-25thiaz-bala-psdap
4259: bim-24oxaz-gly-betapy4259: bim-24oxaz-gly-betapy
4260: bhs-25oxaz-gly-suabu4260: bhs-25oxaz-gly-suabu
4261: bim-25thioph-gly-betapy4261: bim-25thioph-gly-betapy
4262: bim-25methiaz-bala-aspibua 15 4263: bhs-oxadiaz-gly-betahdcph4262: bim-25methiaz-bala-aspibua 15 4263: bhs-oxadiaz-gly-betahdcph
4264 : ibhs-24thiaz-bala-betacthioph4264: ibhs-24thiaz-bala-betacthioph
4265: tolhs-24thiaz-gly-betaamibe4265: tolhs-24thiaz-gly-betaamibe
4266: tolhs-24thioph-bala-beta3quin4266: tolhs-24thioph-bala-beta3quin
4267: ibhs-25thiaz-bala-betamesu 20 4268: phhs-oxadiaz-bala-zdapee4267: ibhs-25thiaz-bala-betamesu 20 4268: phhs-oxadiaz-bala-zdapee
4269: ibhs-24thiaz-bala-betahmofu4269: ibhs-24thiaz-bala-betahmofu
4270: bhs-25methiaz-bala-betaet4270: bras-25methiaz-bala-betaet
4271: ibhs-25thiaz-gly-betaheph4271: ibhs-25thiaz-gly-betaheph
4272 : ibhs-24thiaz-bala-beta34meoph4272: ibhs-24thiaz-bala-beta34meoph
4273 : ibhs-nme35pyr-bala-betathioph4273: ibhs-nme35pyr-bala-betathioph
25 4274 : bhs-25methiaz-bala-betafluo25 4274: bras-25methiaz-bala-betafluo
4275: bim-25oxaz-ala-betapy4275: bim-25oxaz-ala-betapy
4276 : phhs-24thioph-bala-betapbiph4276: phhs-24thioph-bala-betapbiph
4277: tolhs-24thiaz-gly-betadito4277: tolhs-24thiaz-gly-betadito
4278: bim-42oxaz-ala-psdap 30 4279: bhs-24thiophme-gly-zdap4278: bim-42oxaz-ala-psdap 30 4279: bhs-24thiophme-gly-zdap
4280 : tolhs-24thiaz-bala-betadcphtb4280: tolhs-24thiaz-bala-betadcphtb
4281: bhs-25thiaz-bala-betabpy4281: bhs-25thiaz-bala-betabpy
4282 : phhs-me25oxaz-leu-betaph4282: phhs-me25oxaz-leu-betaph
4283: phhs-nme35pyr-gly-beta3quin 35 4284: bhs-oxadiaz-bala-betabthioph4283: phhs-nme35pyr-gly-beta3quin 35 4284: bhs-oxadiaz-bala-betabthioph
4285: bim-nme35pyr-bala-aspibua4285: bim-nme35pyr-bala-aspibua
4286: bhs-25thiaz-bala-betaphethio4286: bhs-25thiaz-bala-betaphethio
4287: ibhs-25thiaz-bala-betaoxaz4287: ibhs-25thiaz-bala-betaoxaz
4288 : bhs-nme35pyr-gly-zdaptb4288: bhs-nme35pyr-gly-zdaptb
4289 : ibhs-25oxaz-bala-busu2be4289: ibhs-25oxaz-bala-busu2be
40 4290 : bhs-25methiaz-nmgly-betadmoph40 4290: bhs-25methiaz-nmgly-betadmoph
4291: tolhs-oxadiaz-bala-betameph4291: tolhs-oxadiaz-bala-betameph
4292: bhs-24thiaz-gly-betabiph4292: bhs-24thiaz-gly-betabiph
4293: ibhs-25methiaz-bala-betapym4293: ibhs-25methiaz-bala-betapym
4294: tolhs-nme35pyr-gly-betahioph 45 4295: tolhs-25methiaz-bala-psdapch4294: tolhs-nme35pyr-gly-betahioph 45 4295: tolhs-25methiaz-bala-psdapch
4296: 2py-25thiaz-gly-asppha4296: 2py-25thiaz-gly-asppha
4297: tolhs-24thiaz-bala-betahc 4298: 2pmhs-25thioph-gly-betapy 4299: ibhs-24thiaz-bala-betaph4297: tolhs-24thiaz-bala-betahc 4298: 2 pmhs-25thioph-gly-betapy 4299: ibhs-24thiaz-bala-betaph
4300: impy-25methiaz-bala-betamethi 4301 : phhs-oxadiaz-gly-betathiobe4300: impy-25methiaz-bala-betamethi 4301: phhs-oxadiaz-gly-betathiobe
5 4302: ibhs-25thiaz-gly-betathioph5 4302: ibhs-25thiaz-gly-betathioph
4303: gua-25thiaz-gly-betacthioph4303: gua-25thiaz-gly-betacthioph
4304: phhs-24thioph-gly-beta3quin4304: phhs-24thioph-gly-beta3quin
4305: phhs-oxadiaz-bala-betafph4305: phhs-oxadiaz-bala-betafph
4306: phhs-ithiadiaz-bala-betaoxope4306: phhs-ithiadiaz-bala-betaoxope
4307 : tolhs-25methiaz-bala-betahdcph4307: tolhs-25methiaz-bala-betahdcph
1010
4308: bhs-24oxaz-leu-psdap4308: bras-24oxaz-leu-psdap
4309 : ibhs-24thiaz-bala-betahdcph4309: ibhs-24thiaz-bala-betahdcph
4310: gua-24thiaz-gly-betahc4310: gua-24thiaz-gly-betahc
4311: phhs-24thiaz-bala-betadbph4311: phhs-24thiaz-bala-betadbph
4312 : 2pmhs-25oxaz-gly-betatbuph 15 4313: ibhs-24thioph-bala-psdap4312: 2 pmhs-25oxaz-gly-betatbuph 15 4313: ibhs-24thioph-bala-psdap
4314: bim-24thioph-bala-betapy4314: bim-24thioph-bala-betapy
4315: tolhs-24thiaz-gly-betal3bendi4315: tolhs-24thiaz-gly-betal3bendi
4316: pahs-25thiaz-gly-betapy4316: pahs-25thiaz-gly-betapy
4317: thazep-24thiaz-bala-zdap 20 4318: phhs-24thioph-gly-betameph4317: thazep-24thiaz-bala-zdap 20 4318: phhs-24thioph-gly-betameph
4319: impy-24thioph-gly-betaipr4319: impy-24thioph-gly-betaipr
4320: 2py-42nmeim-bala-betatrif4320: 2py-42nmeim-bala-betatrif
4321: phhs-24thiaz-gly-psdapee4321: phhs-24thiaz-gly-psdapee
4322: phhs-oxadiaz-gly-beta35dbph4322: phhs-oxadiaz-gly-beta35dbph
4323: thpym-24thiaz-gly-betacbph4323: thpym-24thiaz-gly-betacbph
2525
4324: phhs-24thiaz-bala-zdap4324: phhs-24thiaz-bala-zdap
4325 : ibhs-24thioph-bala-betapyee4325: ibhs-24thioph-bala-betapyee
4326 : tolhs-ithiadiaz-gly-betaipro4326: tolhs-ithiadiaz-gly-betaipro
4327: bhs-26py-gly-zdap4327: bhs-26py-gly-zdap
4328: phhs-ithiadiaz-bala-betal3bendi 30 4329: ibhs-25methiaz-gly-betaheph4328: phhs-ithiadiaz-bala-betal3bendi 30 4329: ibhs-25methiaz-gly-betaheph
4330: bhs-nme35pyr-gly-betacph4330: bhs-nme35pyr-gly-betacph
4331: bhs-thiadiaz-leu-zdap4331: bhs-thiadiaz-leu-zdap
4332: tolhs-24thiaz-gly-betafu34332: tolhs-24thiaz-gly-betafu3
4333: 2py-ithiadiaz-leu-psdap 35 4334: thpym-42pym-gly-beta35dbph4333: 2py-ithiadiaz-leu-psdap 35 4334: thpym-42pym-gly-beta35dbph
4335: bhs-35fur-leu-zdap4335: bras-35fur-leu-zdap
4336: bim-me25thiaz-ala-psdap4336: bim-me25thiaz-ala-psdap
4337: bim-thiadiaz-bala-betapy4337: bim-thiadiaz-bala-betapy
4338: bhs-25thiaz-bala-betadcphee4338: bras-25thiaz-bala-betadcphee
4339 : ibhs-ithiadiaz-bala-betadhbfu4339: ibhs-ithiadiaz-bala-betadhbfu
40 4340: phhs-24thiaz-bala-betafu240 4340: phhs-24thiaz-bala-betafu2
4341: bhs-oxadiaz-bala-aspibua4341: bras-oxadiaz-bala-aspibua
4342 : tolhs-25thiaz-gly-betamethioph4342: tolhs-25thiaz-gly-betamethioph
4343: bhs-25oxaz-nmgly-betadhbfu4343: bhs-25oxaz-nmgly-betadhbfu
4344: 3pmhs-24thiaz-bala-betapy 45 4345: 2py-42pym-ala-zdap4344: 3 pmhs-24thiaz-bala-betapy 45 4345: 2py-42pym-ala-zdap
4346 : tolhs-24thioph-gly-betaoxaz4346: tolhs-24thioph-gly-betaoxaz
4347 : phhs-25oxaz-bala-betaimid 4348: bim-25oxaz-bala-aspibua 4349: phhs-nme35pyr-gly-betathiobe 4350: ibhs-24thioph-bala-betahc 4351 : bhs-nme35pyr-bala-zdapee 5 4352: 2py-24thiaz-bala-betaoxope 4353: bhs-25thiaz-ala-betamesu 4354 : phhs-25methiaz-bala-betah35dc4347: phhs-25oxaz-bala-betaimide 4348: bim-25oxaz-bala-aspibua 4349: phhs-nme35pyr-gly-betathiobe 4350: ibhs-24thioph-bala-betahc 4351: bhs-nme35pyr-bala-zdapee 5 4352: 2py-24thiaz-bala-betaoxope 4353: bhs- 25thiaz-ala-betamesu 4354: phhs-25methiaz-bala-betah35dc
4355: bhs-25oxaz-gly-betacbph4355: bhs-25oxaz-gly-betacbph
4356: tolhs-25thiaz-gly-beta3quin4356: tolhs-25thiaz-gly-beta3quin
4357: bhs-oxadiaz-gly-betadbph4357: bhs-oxadiaz-gly-betadbph
10 4358: tolhs-25oxaz-bala-betameph10 4358: tolhs-25oxaz-bala-betameph
4359: phhs-24thiaz-gly-beta4bph4359: phhs-24thiaz-gly-beta4bph
4360: 2py-me25thiaz-leu-betadcph4360: 2py-me25thiaz-leu-betadcph
4361: 2py-nme35pyr-gly-betapy4361: 2py-nme35pyr-gly-betapy
4362: bhs-25oxaz-bala-betacph 15 4363: bhs-25methiaz-bala-betal3bendi4362: bhs-25oxaz-bala-betacph 15 4363: bhs-25methiaz-bala-betal3bendi
4364: dhim-25thiaz-gly-psdap4364: dhim-25thiaz-gly-psdap
4365: 2py-42nmeim-bala-betadbph4365: 2py-42nmeim-bala-betadbph
4366: bhs-ithiadiaz-gly-betapytb4366: bhs-ithiadiaz-gly-betapytb
4367 : phhs-ithiadiaz-bala-betatos 20 4368: tolhs-oxadiaz-bala-betafu34367: phhs-ithiadiaz-bala-betatos 20 4368: tolhs-oxadiaz-bala-betafu3
4369: 2py-24thiaz-gly-aspbzla4369: 2py-24thiaz-gly-aspbzla
4370: bhs-25oxaz-bala-betaibph4370: bhs-25oxaz-bala-betaibph
4371: ibhs-ithiadiaz-gly-betahb4371: ibhs-ithiadiaz-gly-betahb
4372: ibhs-25thiaz-bala-betadcph4372: ibhs-25thiaz-bala-betadcph
4373 : ibhs-24thiaz-gly-beta23meoph4373: ibhs-24thiaz-gly-beta23meoph
25 4374: tolhs-nme35pyr-bala-betatbuph25 4374: tolhs-nme35pyr-bala-betatbuph
4375: bhs-24thioph-bala-betapyr4375: bras-24thioph-bala-betapyr
4376: ibhs-nme35pyr-gly-betahcbph4376: ibhs-nme35pyr-gly-betahcbph
4377: bhs-53pyrazo-gly-psdap4377: bhs-53pyrazo-gly-psdap
4378: pahs-24thiaz-bala-betameph 30 4379: ibhs-oxadiaz-gly-betabpy4378: pahs-24thiaz-bala-betameph 30 4379: ibhs-oxadiaz-gly-betabpy
4380: tolhs-nme35pyr-gly-betatrif4380: tolhs-nme35pyr-gly-betatrif
4381 : phhs-25thiaz-bala-betabdimo4381: phhs-25thiaz-bala-betabdimo
4382: ibhs-25oxaz-bala-betaheph4382: ibhs-25oxaz-bala-betaheph
4383: tolhs-24thiaz-gly-betaibph 35 4384: 2py-triaz-ala-betapy4383: tolhs-24thiaz-gly-betaibph 35 4384: 2py-triaz-ala-betapy
4385: bhs-25methiaz-gly-betadmph4385: bhs-25methiaz-gly-betadmph
4386: phhs-25thiaz-bala-betaibph4386: phhs-25thiaz-bala-betaibph
4387 : ibhs-25thiaz-gly-betahcbph4387: ibhs-25thiaz-gly-betahcbph
4388: phhs-oxadiaz-bala-beta35dbph4388: phhs-oxadiaz-bala-beta35dbph
4389: bim-nme35pyr-ala-psdap4389: bim-nme35pyr-ala-psdap
40 4390: phhs-25oxaz-bala-betahmofu40 4390: phhs-25oxaz-bala-betahmofu
4391: bim-25thiaz-bala-betatos4391: bim-25thiaz-bala-betatos
4392 : ibhs-25oxaz-bala-psdapee4392: ibhs-25oxaz-bala-psdapee
4393: hts-24thioph-gly-betapy4393: hts-24thioph-gly-betapy
4394 : bhs-25methiaz-bala-beta4bph 45 4395: bhs-me25thiaz-gly-betapy4394: bhs-25methiaz-bala-beta4bph 45 4395: bhs-me25thiaz-gly-betapy
4396: bhs-25methiaz-gly-betaibph4396: bhs-25methiaz-gly-betaibph
4397 : bhs-25oxaz-bala-betaanaphth 4398 : bhs-25thiaz-gly-betaphethio 4399 : phhs-24thiaz-bala-beta23meoph 4400: tolhs-24thiaz-gly-csdap 4401: phhs-oxadiaz-gly-betaol 4402: ibhs-nme35pyr-g1y-aspibua 4403: pahs-25oxaz-gly-betapy 4404 : bhs-oxadiaz-bala-betal3bendi 4405: phhs-24thioph-gly-betafbph 4406: ibhs-25thiaz-gly-betaimid 4407 : bhs-oxadiaz-nmgly-betabnaphth4397: bhs-25oxaz-bala-betaanaphth 4398: bhs-25thiaz-gly-betaphethio 4399: phhs-24thiaz-bala-beta23meoph 4400: tolhs-24thiaz-gly-csdap 4401: phhs-oxadiaz-gly-betaol 4402: ibhs-nme35pyr-g1y-aspibua 4403: pahs-25ox -gly-betapy 4404: bhs-oxadiaz-bala-betal3bendi 4405: phhs-24thioph-gly-betafbph 4406: ibhs-25thiaz-gly-betaimid 4407: bhs-oxadiaz-nmgly-betabnaphth
10 4408: phhs-25oxaz-gly-betainyl 4409: bim-ithiadiaz-gly-aspbzla 4410: tolhs-24thioph-gly-betacph 4411 : bhs-nme35pyr-gly-betaphethio 4412: 2py-42oxaz-gly-betapy10 4408: phhs-25oxaz-gly-betainyl 4409: bim-ithiadiaz-gly-aspbzla 4410: tolhs-24thioph-gly-betacph 4411: bhs-nme35pyr-gly-betaphethio 4412: 2py-42oxaz-gly-betapy
15 4413: ibhs-24thiaz-bala-betamesu 4414: bhs-24thioph-bala-betahb 4415: tolhs-oxadiaz-bala-betahph 4416 : bhs-nme35pyr-bala-betapytb 4417: tolhs-24thiaz-gly-betahc15 4413: ibhs-24thiaz-bala-betamesu 4414: bhs-24thioph-bala-betahb 4415: tolhs-oxadiaz-bala-betahph 4416: bhs-nme35pyr-bala-betapytb 4417: tolhs-24thiaz-gly-betahc
20 4418: bim-35thioph-leu-betadcph 4419: bhs-25methiaz-bala-betahmo 4420 : bim-me25thioph-gly-beta34meoph 4421: 4pmhs-25thiaz-gly-betapy 4422: phhs-25thiaz-bala-betahmph 4423: phhs-25methiaz-gly-aspbzla20 4418: bim-35thioph-leu-betadcph 4419: bhs-25methiaz-bala-betahmo 4420: bim-me25thioph-gly-beta34meoph 4421: 4 pmhs-25thiaz-gly-betapy 4422: phhs-25thiaz-bala-betahmph 4423: phhs- 25methiaz-gly-aspbzla
25 4424: gua-24thiaz-gly-betacthioph 4425: thpym-25thioph-gly-betacbph 4426: dhim-25thiaz-gly-betapy 4427: ibhs-25methiaz-bala-zdap 4428: bhs-25methiaz-bala-busu2be25 4424: gua-24thiaz-gly-betacthioph 4425: thpym-25thioph-gly-betacbph 4426: dhim-25thiaz-gly-betapy 4427: ibhs-25methiaz-bala-zdap 4428: bhs-25methiaz-bala-busu2be
30 4429: bim-24thioph-gly-betahmph 4430: phhs-nme35pyr-g1y-bet ipro 4431 : bhs-me24oxaz-ala-beta34meoph 4432 : bhs-nme35pyr-ala-betacthioph 4433: bim-42oxaz-ala-betapy30 4429: bim-24thioph-gly-betahmph 4430: phhs-nme35pyr-g1y-bet ipro 4431: bhs-me24oxaz-ala-beta34meoph 4432: bhs-nme35pyr-ala-betacthioph 4433: bim-42oxaz-ala-betapy
35 4434: bhs-24thioph-gly-betadmph 4435: phhs-25methiaz-gly-betahbcph 4436 : tolhs-24thioph-gly-betathiobe 4437: ibhs-25oxaz-bala-betaoxaz 4438: ibhs-nme35pyr-bala-betameph 4439 : tolhs-ithiadiaz-gly-betapbiph35 4434: bhs-24thioph-gly-betadmph 4435: phhs-25methiaz-gly-betahbcph 4436: tolhs-24thioph-gly-betathiobe 4437: ibhs-25oxaz-bala-betaoxaz 4438: ibhs-nme35pyr-bala-betameph 4439: tol ithiadiaz-gly-betapbiph
40 4440: bim-24thioph-bala-aspbzla 4441 : 2py-nme35pyr-leu-betapy 4442: dhthi-24oxaz-gly-betapy 4443: tolhs-24thioph-gly-betadmph 4444 : phhs-25thiaz-bala-psdaptb40 4440: bim-24thioph-bala-aspbzla 4441: 2py-nme35pyr-leu-betapy 4442: dhthi-24oxaz-gly-betapy 4443: tolhs-24thioph-gly-betadmph 4444: phhs-25thiaz-bala-psdaptb
45 4445: 2py-me25oxaz-gly-beta34meoph 4446: tolhs-oxadiaz-gly-betapyr 4447: bhs-24thiaz-gly-betamethi 4448: bhs-24thiaz-bala-betaph45 4445: 2py-me25oxaz-gly-beta34meoph 4446: tolhs-oxadiaz-gly-betapyr 4447: bhs-24thiaz-gly-betamethi 4448: bras-24thiaz-bala-betaph
4449: bhs-oxadiaz-bala-betahdcph4449: bras-oxadiaz-bala-betahdcph
4450: gua-25 hioph-gly-betahcbph4450: gua-25 hioph-gly-betahcbph
4451: 2py-52thiaz-gly-betainyl 5 4452: tolhs-oxadiaz-bala-betacthioph4451: 2py-52thiaz-gly-betainyl 5 4452: tolhs-oxadiaz-bala-betacthioph
4453: 2py-25methiaz-gly-betadcph4453: 2py-25methiaz-gly-betadcph
4454: bhs-oxadiaz-gly-betatrif4454: bras-oxadiaz-gly-betatrif
4455: tolhs-24thioph-gly-betabmph4455: tolhs-24thioph-gly-betabmph
4456 : tolhs-25methiaz-bala-betadcph4456: tolhs-25methiaz-bala-betadcph
4457: bim-triaz-ala-betadcph4457: bim-triaz-ala-betadcph
10 4458: bhs-nme35pyr-gly-beta3quin10 4458: bhs-nme35pyr-gly-beta3quin
4459: phhs-24thioph-gly-betahb4459: phhs-24thioph-gly-betahb
4460: phhs-25thiaz-gly-betafbph4460: phhs-25thiaz-gly-betafbph
4461: impy-42nmeim-bala-betadtrif4461: impy-42nmeim-bala-betadtrif
4462: phhs-24thiaz-bala-suabu 15 4463: tolhs-24thioph-bala-betapyr4462: phhs-24thiaz-bala-suabu 15 4463: tolhs-24thioph-bala-betapyr
4464: bhs-25thiaz-ala-betadmoph4464: bhs-25thiaz-ala-betadmoph
4465: bhs-25thiaz-bala-betah35dc4465: bhs-25thiaz-bala-betah35dc
4466: hts-24thiaz-gly-betapy4466: hts-24thiaz-gly-betapy
4467 : phhs-ithiadiaz-bala-betahdcph 20 4468: ibhs-24thiaz-bala-betamethioph4467: phhs-ithiadiaz-bala-betahdcph 20 4468: ibhs-24thiaz-bala-betamethioph
4469: bim-oxadiaz-gly-psdap4469: bim-oxadiaz-gly-psdap
4470: bim-oxadiaz-leu-zdap4470: bim-oxadiaz-leu-zdap
4471: ibhs-oxadiaz-gly-ibsdap4471: ibhs-oxadiaz-gly-ibsdap
4472 : tolhs-me24thioph-leu-beta34meoph4472: tolhs-me24thioph-leu-beta34meoph
4473: phhs-ithiadiaz-bala-aspaba4473: phhs-ithiadiaz-bala-aspaba
25 4474 : ibhs-oxadiaz-bala-betah35dc25 4474: ibhs-oxadiaz-bala-betah35dc
4475 : phhs-25methiaz-bala-betapych4475: phhs-25methiaz-bala-betapych
4476: phhs-24thioph-gly-betabph4476: phhs-24thioph-gly-betabph
4477: impy-25thiaz-gly-betambiph4477: impy-25thiaz-gly-betambiph
4478: bhs-25thiaz-gly-betafu2 30 4479: ibhs-oxadiaz-gly-psdapee4478: bhs-25thiaz-gly-betafu2 30 4479: ibhs-oxadiaz-gly-psdapee
4480: bhs-24 hioph-bala-betaimid4480: bhs-24 hioph-bala-betaimide
4481: tolhs-24thioph-gly-psdap4481: tolhs-24thioph-gly-psdap
4482 : ibhs-oxadiaz-bala-psdapch4482: ibhs-oxadiaz-bala-psdapch
4483 : phhs-24thiaz-gly-betabthioph 35 4484: bim-26py-gly-betadcph4483: phhs-24thiaz-gly-betabthioph 35 4484: bim-26py-gly-betadcph
4485: bhs-24thioph-bala-betahmph4485: bhs-24thioph-bala-betahmph
4486: ibhs-25oxaz-gly-betafphe4486: ibhs-25oxaz-gly-betafphe
4487: bhs-25oxaz-gly-betaipr4487: bhs-25oxaz-gly-betaipr
4488: tolhs-24thiaz-gly-betahdcph4488: tolhs-24thiaz-gly-betahdcph
4489: gua-24oxaz-gly-betahmofu4489: gua-24oxaz-gly-betahmofu
40 4490 : tolhs-24thioph-bala-betacph40 4490: tolhs-24thioph-bala-betacph
4491 : tolhs-24thioph-gly-beta34meoph4491: tolhs-24thioph-gly-beta34meoph
4492: bhs-oxadiaz-bala-beta35dbph4492: bhs-oxadiaz-bala-beta35dbph
4493: phhs-ithiadiaz-gly-betaet4493: phhs-ithiadiaz-gly-betet
4494: bim-24thioph-bala-csdap 45 4495: bhs-25methiaz-gly-zdaptb4494: bim-24thioph-bala-csdap 45 4495: bhs-25methiaz-gly-zdaptb
4496 : bhs-nme35pyr-bala-betaphethio4496: bhs-nme35pyr-bala-betaphethio
4497 : ibhs-24thiaz-gly-betathioph 4498: tolhs-24thiaz-bala-betapych4497: ibhs-24thiaz-gly-betathioph 4498: tolhs-24thiaz-bala-betapych
4499 : tolhs-oxadiaz-gly-betadcphch4499: tolhs-oxadiaz-gly-betadcphch
4500: bhs-ithiadiaz-leu-betadcph4500: bhs-ithiadiaz-leu-betadcph
4501: phhs-nme35pyr-gly-betaimid 5 4502: tolhs-24thiaz-gly-betahni4501: phhs-nme35pyr-gly-betaimide 5 4502: tolhs-24thiaz-gly-betahni
4503: 2py-26py-gly-csdap4503: 2py-26py-gly-csdap
4504: bhs-triaz-bala-zdap4504: bras-triaz-bala-zdap
4505: tolhs-25oxaz-bala-betapyee4505: tolhs-25oxaz-bala-betapyee
4506: phhs-oxadiaz-gly-betabediox4506: phhs-oxadiaz-gly-betabediox
4507: bhs-25thiaz-gly-betapy4507: bhs-25thiaz-gly-betapy
4508 : tolhs-ithiadiaz-bala-beta23meoph4508: tolhs-ithiadiaz-bala-beta23meoph
4509: gua-26py-gly-betambiph4509: gua-26py-gly-betambiph
4510: 2pmhs-24thioph-gly-betameph4510: 2 pmhs-24thioph-gly-betameph
4511: phhs-oxadiaz-bala-betaipro4511: phhs-oxadiaz-bala-betaipro
4512: tolhs-nme35pyr-gly-betaimid 15 4513: tolhs-nme35pyr-gly-beta34dcph4512: tolhs-nme35pyr-gly-betaimide 15 4513: tolhs-nme35pyr-gly-beta34dcph
4514: phhs-25thiaz-bala-betabpy4514: phhs-25thiaz-bala-betabpy
4515: 2py-24thioph-gly-psdap4515: 2py-24thioph-gly-psdap
4516 : ibhs-24thioph-gly-betadcphch4516: ibhs-24thioph-gly-betadcphch
4517 : phhs-25methiaz-gly-betafphe 20 4518: tolhs-25methiaz-bala-betambiph4517: phhs-25methiaz-gly-betafphe 20 4518: tolhs-25methiaz-bala-betambiph
4519 : tolhs-24thiaz-bala-betatrif4519: tolhs-24thiaz-bala-betatrif
4520: phhs-oxadiaz-gly-betahc4520: phhs-oxadiaz-gly-betahc
4521: bim-oxadiaz-bala-zdap4521: bim-oxadiaz-bala-zdap
4522: phhs-25methiaz-bala-betahb4522: phhs-25methiaz-bala-betahb
4523: phhs-25methiaz-gly-zdapee4523: phhs-25methiaz-gly-zdapee
4524: bim-25thiaz-gly-betadmph4524: bim-25thiaz-gly-betadmph
4525: phhs-25oxaz-gly-betatbuph4525: phhs-25oxaz-gly-betatbuph
4526: phhs-25oxaz-gly-zdapee4526: phhs-25oxaz-gly-zdapee
4527: bhs-nme35pyr-ala-betahmph4527: bhs-nme35pyr-ala-betahmph
4528: 2py-me24thiaz-ala-zdap 30 4529: tolhs-ithiadiaz-bala-betahdbph4528: 2py-me24thiaz-ala-zdap 30 4529: tolhs-ithiadiaz-bala-betahdbph
4530: ibhs-24thiaz-gly-zdapee4530: ibhs-24thiaz-gly-zdapee
4531: tolhs-25methiaz-bala-betadcphee4531: tolhs-25methiaz-bala-betadcphee
4532 : phhs-nme35pyr-bala-betaanaphth4532: phhs-nme35pyr-bala-betaanaphth
4533: bhs-nme35pyr-bala-betaanaphth 35 4534: tolhs-nme35pyr-gly-betathiome4533: bhs-nme35pyr-bala-betaanaphth 35 4534: tolhs-nme35pyr-gly-betathiome
4535: ibhs-25methiaz-gly-betacthioph4535: ibhs-25methiaz-gly-betacthioph
4536: bhs-24thioph-gly-betah35dc4536: bhs-24thioph-gly-betah35dc
4537: bim-24oxaz-ala-psdap4537: bim-24oxaz-ala-psdap
4538: ibhs-oxadiaz-gly-betadcphee4538: ibhs-oxadiaz-gly-betadcphee
4539: tolhs-oxadiaz-bala-betaol4539: tolhs-oxadiaz-bala-betaol
40 4540 : ibhs-ithiadiaz-bala-aspbzla40 4540: ibhs-ithiadiaz-bala-aspbzla
4541: 2py-26py-ala-zdap4541: 2py-26py-ala-zdap
4542: tolhs-oxadiaz-gly-betafu34542: tolhs-oxadiaz-gly-betafu3
4543: bhs-me24thioph-leu-zdap4543: bhs-me24thioph-leu-zdap
4544: dhpyrr-24oxaz-gly-betameph 45 4545: bhs-24thiaz-gly-psdap4544: dhpyrr-24oxaz-gly-betameph 45 4545: bhs-24thiaz-gly-psdap
4546: tolhs-oxadiaz-bala-betambiph4546: tolhs-oxadiaz-bala-betambiph
4547: phhs-24thioph-gly-betafphe 4548 : tolhs-ithiadiaz-bala-betacbph4547: phhs-24thioph-gly-betafphe 4548: tolhs-ithiadiaz-bala-betacbph
4549 : phhs-24thiaz-bala-betadcph.ee4549: phhs-24thiaz-bala-betadcph.ee
4550: ibhs-25oxaz-gly-betampy4550: ibhs-25oxaz-gly-betampy
4551: phhs-oxadiaz-bala-aspaba 5 4552: bim-25oxaz-bala-betapyr4551: phhs-oxadiaz-bala-aspaba 5 4552: bim-25oxaz-bala-betapyr
4553: phhs-25oxaz-bala-beta35dbph4553: phhs-25oxaz-bala-beta35dbph
4554: ibhs-25thiaz-bala-ibsdap4554: ibhs-25thiaz-bala-ibsdap
4555: ibhs-nme35pyr-gly-betaoxope4555: ibhs-nme35pyr-gly-betaoxope
4556: tolhs-oxadiaz-gly-betabpy4556: tolhs-oxadiaz-gly-betabpy
4557: phhs-nme35pyr-bala-beta3quin4557: phhs-nme35pyr-bala-beta3quin
10 4558: tolhs-nme35pyr-gly-betamesu10 4558: tolhs-nme35pyr-gly-betamesu
4559: bhs-24thiaz-bala-betacph4559: bras-24thiaz-bala-betacph
4560 : ibhs-nme35pyr-bala-betaheph4560: ibhs-nme35pyr-bala-betaheph
4561: 2pmhs-24thioph-bala-beta4bph4561: 2 pmhs-24thioph-bala-beta4bph
4562: bhs-thiadiaz-bala-betapy 15 4563: phhs-nme35pyr-bala-betadbph4562: bhs-thiadiaz-bala-betapy 15 4563: phhs-nme35pyr-bala-betadbph
4564: 2py-26py-gly-betapy4564: 2py-26py-gly-betapy
4565: bim-me24thioph-ala-psdap4565: bim-me24thioph-ala-psdap
4566 : tolhs-me24thioph-ala-betaph4566: tolhs-me24thioph-ala-betaph
4567 : phhs-24thioph-bala-betacthioph 20 4568: phhs-ithiadiaz-bala-betapym4567: phhs-24thioph-bala-betacthioph 20 4568: phhs-ithiadiaz-bala-betapym
4569: bhs-24thiaz-bala-betatrif4569: bras-24thiaz-bala-betatrif
4570: phhs-25thiaz-bala-betaimid4570: phhs-25thiaz-bala-betaimide
4571: bhs-24thiaz-bala-betaet4571: bhs-24thiaz-bala-betet
4572 : 2pmhs-24thioph-bala-betal3bendi4572: 2 pmhs-24thioph-bala-betal3bendi
4573: 2py-me24thiaz-leu-psdap4573: 2py-me24thiaz-leu-psdap
25 4574: tolhs-24thioph-bala-betaph25 4574: tolhs-24thioph-bala-betaph
4575: ibhs-25oxaz-gly-betahmo4575: ibhs-25oxaz-gly-betahmo
4576: phhs-nme35pyr-bala-betapytb4576: phhs-nme35pyr-bala-betapytb
4577: tolhs-ithiadiaz-gly-betadmph4577: tolhs-ithiadiaz-gly-betadmph
4578: tolhs-ithiadiaz-gly-betahmofu 30 4579: phhs-24thioph-bala-betahcbph4578: tolhs-ithiadiaz-gly-betahmofu 30 4579: phhs-24thioph-bala-betahcbph
4580 : phhs-25methiaz-gly-beta4bph4580: phhs-25methiaz-gly-beta4bph
4581: phhs-nme35pyr-bala-betafluo4581: phhs-nme35pyr-bala-betafluo
4582 : tolhs-24thiaz-gly-betah35dc4582: tolhs-24thiaz-gly-betah35dc
4583: ibhs-25methiaz-gly-betaet 35 4584: ibhs-25methiaz-bala-betabmph4583: ibhs-25methiaz-gly-betet 35 4584: ibhs-25methiaz-bala-betabmph
4585: tolhs-25oxaz-gly-betahph4585: tolhs-25oxaz-gly-betahph
4586: bhs-ithiadiaz-nmgly-betameph4586: bhs-ithiadiaz-nmgly-betameph
4587: ibhs-ithiadiaz-bala-ibsdap4587: ibhs-ithiadiaz-bala-ibsdap
4588: 2pmhs-25thiaz-bala-zdap4588: 2 pmhs-25thiaz-bala-zdap
4589: bhs-25oxaz-gly-beta3quin4589: bhs-25oxaz-gly-beta3quin
40 4590: ibhs-ithiadiaz-gly-psdap40 4590: ibhs-ithiadiaz-gly-psdap
4591 : tolhs-ithiadiaz-bala-betathio34591: tolhs-ithiadiaz-bala-betathio3
4592 : phhs-24thiaz-bala-betahdbph4592: phhs-24thiaz-bala-betahdbph
4593 : phhs-25methiaz-bala-betafu24593: phhs-25methiaz-bala-betafu2
4594: bhs-nme35pyr-bala-betafphe 45 4595: ibhs-24thioph-gly-betapym4594: bhs-nme35pyr-bala-betafphe 45 4595: ibhs-24thioph-gly-betapym
4596: tolhs-25thiaz-gly-csdap4596: tolhs-25thiaz-gly-csdap
4597: ibhs-nme35pyr-gly-betafphe 4598: gua-24thiaz-gly-betabediox4597: ibhs-nme35pyr-gly-betafphe 4598: gua-24thiaz-gly-betabediox
4599: bim-25thioph-gly-betameph4599: bim-25thioph-gly-betameph
4600: 2py-25oxaz-gly-zdap4600: 2py-25oxaz-gly-zdap
4601 : ibhs-ithiadiaz-gly-betabediox 5 4602: bhs-25oxaz-gly-betabediox4601: ibhs-ithiadiaz-gly-betabediox 5 4602: bhs-25oxaz-gly-betabediox
4603 : ibhs-25methiaz-bala-betah35dc4603: ibhs-25methiaz-bala-betah35dc
4604: bhs-24thiazme-ala-betameph4604: bhs-24thiazme-ala-betameph
4605: gua-24thiaz-gly-betaimid4605: gua-24thiaz-gly-betaimide
4606: bhs-25thiaz-gly-betaipro4606: bhs-25thiaz-gly-betaipro
4607: ibhs-25methiaz-bala-betafu24607: ibhs-25methiaz-bala-betafu2
1010
4608: bhs-24thioph-bala-psdapee4608: bhs-24thioph-bala-psdapee
4609: phhs-24thiaz-gly-betah35dc4609: phhs-24thiaz-gly-betah35dc
4610: bhs-52thiaz-ala-psdap4610: bhs-52thiaz-ala-psdap
4611: ibhs-25oxaz-gly-betapyee4611: ibhs-25oxaz-gly-betapyee
4612: ibhs-25thiaz-gly-psdap 15 4613: nmhs-25oxaz-bala-zdap4612: ibhs-25thiaz-gly-psdap 15 4613: nmhs-25oxaz-bala-zdap
4614 : tolhs-24thiaz-gly-betabdimo4614: tolhs-24thiaz-gly-betabdimo
4615 : bhs-25thiaz-ala-beta23meoph4615: bhs-25thiaz-ala-beta23meoph
4616: gua-24thiaz-gly-betampy4616: gua-24thiaz-gly-betampy
4617 : tolhs-ithiadiaz-gly-betatrif 20 4618: bhs-42pym-ala-betameph4617: tolhs-ithiadiaz-gly-betatrif 20 4618: bhs-42pym-ala-betameph
4619 : bhs-25methiaz-ala-betacthioph4619: bhs-25methiaz-ala-betacthioph
4620 : phhs-oxadiaz-bala-betadcphtb4620: phhs-oxadiaz-bala-betadcphtb
4621: bhs-24thioph-bala-betafu34621: bhs-24thioph-bala-betafu3
4622: tolhs-25oxaz-bala-betafu24622: tolhs-25oxaz-bala-betafu2
4623: bhs-25oxaz-bala-betaamibe4623: bras-25oxaz-bala-betaamibe
25 4624: bim-25methiaz-gly-betadcph25 4624: bim-25methiaz-gly-betadcph
4625: gua-24thiaz-gly-betacph4625: gua-24thiaz-gly-betacph
4626 : bhs-24thiaz-nmgly-beta34meoph4626: bhs-24thiaz-nmgly-beta34meoph
4627 : tolhs-me25thioph-bala-betaph4627: tolhs-me25thioph-bala-betaph
4628: bhs-nme35pyr-gly-betafluo 30 4629: ibhs-25thiaz-bala-betahmph4628: bhs-nme35pyr-gly-betafluo 30 4629: ibhs-25thiaz-bala-betahmph
4630: phhs-25oxaz-bala-betaph4630: phhs-25oxaz-bala-betaph
4631 : tolhs-me24thioph-ala-beta34meoph4631: tolhs-me24thioph-ala-beta34meoph
4632: bhs-nme35pyr-gly-beta35dbph4632: bhs-nme35pyr-gly-beta35dbph
4633 : dimethpym-24 hiaz-gly-betadcph 35 4634: ibhs-25methiaz-bala-betaimid4633: dimethpym-24 hiaz-gly-betadcph 35 4634: ibhs-25methiaz-bala-betaimid
4635 : ibhs-24thioph-bala-betabthioph4635: ibhs-24thioph-bala-betabthioph
4636 : tolhs-nme35pyr-bala-betapyee4636: tolhs-nme35pyr-bala-betapyee
4637: hyd-25thiaz-gly-betainyl4637: hyd-25thiaz-gly-betainyl
4638: tolhs-25oxaz-bala-betapyr4638: tolhs-25oxaz-bala-betapyr
4639 : bhs-ithiadiaz-gly-betahdcph4639: bhs-ithiadiaz-gly-betahdcph
40 4640: bhs-oxadiaz-bala-betadmoph40 4640: bras-oxadiaz-bala-betadmoph
4641: phhs-me25oxaz-ala-betadcph4641: phhs-me25oxaz-ala-betadcph
4642: phhs-25methiaz-bala-betameph4642: phhs-25methiaz-bala-betameph
4643: bhs-24thiaz-gly-betahc4643: bhs-24thiaz-gly-betahc
4644: bhs-me24thioph-leu-betapy 45 4645: ibhs-25methiaz-bala-betahc4644: bhs-me24thioph-leu-betapy 45 4645: ibhs-25methiaz-bala-betahc
4646: phhs-me24oxaz-ala-betaph4646: phhs-me24oxaz-ala-betaph
4647: phhs-24thiaz-gly-betahmofu 4648: bhs-ithiadiaz-ala-betadmoph4647: phhs-24thiaz-gly-betahmofu 4648: bhs-ithiadiaz-ala-betadmoph
4649 : dimethpym-25thioph-gly-betahdcph4649: dimethpym-25thioph-gly-betahdcph
4650 : bim-25methiaz-bala-betadcph4650: bim-25methiaz-bala-betadcph
4651: bhs-24thioph-nmg1y-betadmoph 5 4652: tolhs-25methiaz-bala-betatbuph4651: bhs-24thioph-nmg1y-betadmoph 5 4652: tolhs-25methiaz-bala-betatbuph
4653 : phhs-24thiaz-gly-betathiome4653: phhs-24thiaz-gly-betathioma
4654: phhs-25oxaz-gly-psdaptb4654: phhs-25oxaz-gly-psdaptb
4655 : ibhs-ithiadiaz-bala-betapbiph4655: ibhs-ithiadiaz-bala-betapbiph
4656: ibhs-nme35pyr-bala-betaet4656: ibhs-nme35pyr-bala-betet
4657: tolhs-25thiaz-bala-zdaptb4657: tolhs-25thiaz-bala-zdaptb
10 4658: bhs-25thiaz-gly-beta3quin10 4658: bhs-25thiaz-gly-beta3quin
4659: bim-52thiaz-ala-betainyl4659: bim-52thiaz-ala-betainyl
4660: bhs-24thioph-ala-betadito4660: bhs-24thioph-ala-betadito
4661: 2py-42nmeim-ala-psdap4661: 2py-42nmeim-ala-psdap
4662: phhs-25thiaz-gly-beta3quin 15 4663: tolhs-oxadiaz-bala-betal3bendi4662: phhs-25thiaz-gly-beta3quin 15 4663: tolhs-oxadiaz-bala-betal3bendi
4664: ibhs-25methiaz-gly-betabmph4664: ibhs-25methiaz-gly-betabmph
4665: ibhs-25methiaz-bala-beta23meoph4665: ibhs-25methiaz-bala-beta23meoph
4666: bhs-24thioph-gly-betahb4666: bhs-24thioph-gly-betahb
4667: tolhs-oxadiaz-gly-betafluo 20 4668: gua-24thiaz-gly-betabph4667: tolhs-oxadiaz-gly-betafluo 20 4668: gua-24thiaz-gly-betabph
4669: ibhs-25oxaz-gly-aspaba4669: ibhs-25oxaz-gly-aspaba
4670: bhs-25oxaz-ala-zdap4670: bhs-25oxaz-ala-zdap
4671: tolhs-25thiaz-bala-betahni4671: tolhs-25thiaz-bala-betahni
4672: bim-42nmeim-gly-betamesu4672: bim-42nmeim-gly-betamesu
4673: dhthi-24thiaz-gly-betapy4673: dhthi-24thiaz-gly-betapy
25 4674: phhs-nme35pyr-bala-psdap25 4674: phhs-nme35pyr-bala-psdap
4675: ibhs-25oxaz-gly-betatos4675: ibhs-25oxaz-gly-betatos
4676: bhs-nme35pyr-gly-betapyee4676: bhs-nme35pyr-gly-betapyee
4677: 2py-24thiaz-bala-psdap4677: 2py-24thiaz-bala-psdap
4678: tolhs-oxadiaz-gly-betah.35dc 30 4679: tolhs-24thioph-bala-betapytb4678: tolhs-oxadiaz-gly-betah. 35dc 30 4679: tolhs-24thioph-bala-betapytb
4680: gua-24thiaz-gly-beta34dcph4680: gua-24thiaz-gly-beta34dcph
4681: phhs-24thioph-bala-zdap4681: phhs-24thioph-bala-zdap
4682: bhs-ithiadiaz-bala-betahni4682: bhs-ithiadiaz-bala-betahni
4683: gua-25thiaz-gly-betampy 35 4684: phhs-nme35pyr-bala-beta34dcph4683: gua-25thiaz-gly-betampy 35 4684: phhs-nme35pyr-bala-beta34dcph
4685: tolhs-nme35pyr-bala-betahph4685: tolhs-nme35pyr-bala-betahph
4686: bhs-24thioph-ala-betameph4686: bhs-24thioph-ala-betameph
4687: phhs-25thiaz-bala-betabediox4687: phhs-25thiaz-bala-betabediox
4688: ibhs-24thioph-gly-betahmph4688: ibhs-24thioph-gly-betahmph
4689: tolhs-nme35pyr-bala-betahmph4689: tolhs-nme35pyr-bala-betahmph
40 4690: bhs-25oxaz-gly-betampy40 4690: bhs-25oxaz-gly-betampy
4691 : bhs-ithiadiaz-bala-beta4bph4691: bhs-ithiadiaz-bala-beta4bph
4692 : phhs-25methiaz-gly-betadtrif4692: phhs-25methiaz-gly-betadtrif
4693: bhs-me25thiaz-gly-zdap4693: bhs-me25thiaz-gly-zdap
4694 : phhs-25oxaz-gly-busu2be 45 4695: bhs-nme35pyr-bala-betafu24694: phhs-25oxaz-gly-busu2be 45 4695: bhs-nme35pyr-bala-betafu2
4696 : ibhs-25methiaz-bala-betathiobe4696: ibhs-25methiaz-bala-betathiobe
4697: ibhs-25oxaz-gly-betabdimo 4698: bim-ithiadiaz-ala-psdap 4699: tolhs-oxadiaz-gly-betaimid 4700: ibhs-24thioph-gly-betaftrif4697: ibhs-25oxaz-gly-betabdimo 4698: bim-ithiadiaz-ala-psdap 4699: tolhs-oxadiaz-gly-betaimid 4700: ibhs-24thioph-gly-betaftrif
4701: 2py-me25thiaz-ala-betadcph 5 4702: ibhs-25methiaz-bala-suabu4701: 2py-me25thiaz-ala-betadcph 5 4702: ibhs-25methiaz-bala-suabu
4703: bhs-24thiaz-bala-betafu34703: bhs-24thiaz-bala-betafu3
4704 : ibhs-25thiaz-gly-betal3bendi4704: ibhs-25thiaz-gly-betal3bendi
4705: bim-53pyrazo-gly-zdap4705: bim-53pyrazo-gly-zdap
4706 : bhs-nme35pyr-bala-betapych4706: bhs-nme35pyr-bala-betapych
4707 : bhs-25methiaz-bala-betahdcph4707: bras-25methiaz-bala-betahdcph
1010
4708: phhs-24thiaz-gly-betaphethio4708: phhs-24thiaz-gly-betaphethio
4709 : ibhs-25methiaz-gly-betahmofu4709: ibhs-25methiaz-gly-betahmofu
4710: bhs-25oxaz-bala-betahmofu4710: bras-25oxaz-bala-betahmofu
4711: phhs-25methiaz-gly-betafbph4711: phhs-25methiaz-gly-betafbph
4712: ibhs-24thiaz-gly-betamethi 15 4713: ibhs-25methiaz-gly-psdap4712: ibhs-24thiaz-gly-betamethi 15 4713: ibhs-25methiaz-gly-psdap
4714: phhs-nme35pyr-bala-betadmph4714: phhs-nme35pyr-bala-betadmph
4715 : phhs-oxadiaz-gly-betal3bendi4715: phhs-oxadiaz-gly-betal3bendi
4716: tolhs-24thiaz-bala-betadcphee4716: tolhs-24thiaz-bala-betadcphee
4717: bhs-ithiadiaz-gly-betatos 20 4718: ibhs-25oxaz-gly-betaphethioa4717: bhs-ithiadiaz-gly-betatos 20 4718: ibhs-25oxaz-gly-betaphethioa
4719: ibhs-nme35pyr-gly-beta4bph4719: ibhs-nme35pyr-gly-beta4bph
4720: bhs-oxadiaz-nmgly-betahph4720: bhs-oxadiaz-nmgly-betahph
4721 : tolhs-ithiadiaz-bala-betahcbph4721: tolhs-ithiadiaz-bala-betahcbph
4722: bhs-25thiaz-gly-betabdimo4722: bhs-25thiaz-gly-betabdimo
4723: bhs-24thiaz-ala-ibsdap4723: bhs-24thiaz-ala-ibsdap
25 4724: phhs-25methiaz-bala-betafph25 4724: phhs-25methiaz-bala-betafph
4725: bhs-ithiadiaz-gly-betambiph4725: bhs-ithiadiaz-gly-betambiph
4726: gua-25methiaz-bala-betadcph4726: gua-25methiaz-bala-betadcph
4727: bhs-nme35pyr-ala-betathioph4727: bhs-nme35pyr-ala-betathioph
4728 : ibhs-25thiaz-gly-betadcphtb 30 4729: bhs-nme35pyr-bala-betahni4728: ibhs-25thiaz-gly-betadcphtb 30 4729: bhs-nme35pyr-bala-betahni
4730: ibhs-24thiaz-bala-betaamibe4730: ibhs-24thiaz-bala-betaamibe
4731: bhs-me24thiaz-ala-zdap4731: bhs-me24thiaz-ala-zdap
4732: phhs-24thiaz-gly-betaph4732: phhs-24thiaz-gly-betaph
4733: ibhs-25methiaz-gly-betahb 35 4734: bhs-24thiaz-gly-betatrif4733: ibhs-25methiaz-gly-betahb 35 4734: bhs-24thiaz-gly-betatrif
4735: bhs-25oxaz-gly-aspbzla4735: bhs-25oxaz-gly-aspbzla
4736: phhs-nme35pyr-gly-betadmoph4736: phhs-nme35pyr-gly-betadmoph
4737: bim-25oxaz-ala-zdap4737: bim-25oxaz-ala-zdap
4738: gua-24thiaz-gly-betaibph4738: gua-24thiaz-gly-betaibph
4739: ibhs-nme35pyr-gly-betapyee4739: ibhs-nme35pyr-gly-betapyee
40 4740: dhim-25thiaz-gly-zdap40 4740: dhim-25thiaz-gly-zdap
4741: tolhs-25methiaz-bala-beta3quin4741: tolhs-25methiaz-bala-beta3quin
4742 : tolhs-me24thioph-bala-betadcph4742: tolhs-me24thioph-bala-betadcph
4743 : ibhs-oxadiaz-bala-betaomebendi4743: ibhs-oxadiaz-bala-betaomebendi
4744: tolhs-25thiaz-gly-betaheph 45 4745: bhs-53pyrazo-leu-betapy4744: tolhs-25thiaz-gly-betaheph 45 4745: bhs-53pyrazo-leu-betapy
4746: bim-25fur-bala-psdap4746: bim-25fur-bala-psdap
4747: bim-25thiaz-leu-psdap 4748: bim-42nmeim-bala-zdap4747: bim-25thiaz-leu-psdap 4748: bim-42nmeim-bala-zdap
4749 : gua-26py-gly-betabmph4749: gua-26py-gly-betabmph
4750: bim-me25thiaz-leu-beta34meoph4750: bim-me25thiaz-leu-beta34meoph
4751: bim-oxadiaz-bala-asppha 5 4752: bhs-24im-gly-betapy4751: bim-oxadiaz-bala-asppha 5 4752: bhs-24im-gly-betapy
4753 : tolhs-25thiaz-bala-betadtrif4753: tolhs-25thiaz-bala-betadtrif
4754 : phhs-25methiaz-bala-betapyr4754: phhs-25methiaz-bala-betapyr
4755: 2py-24thiaz-gly-betadito4755: 2py-24thiaz-gly-betadito
4756: ibhs-24thioph-gly-betadmph4756: ibhs-24thioph-gly-betadmph
4757: phhs-oxadiaz-bala-psdaptb4757: phhs-oxadiaz-bala-psdaptb
10 4758: bhs-me24thioph-ala-betapy10 4758: bhs-me24thioph-ala-betapy
4759: tolhs-me25thiaz-leu-psdap4759: tolhs-me25thiaz-leu-psdap
4760: tolhs-24thiaz-bala-beta35dbph4760: tolhs-24thiaz-bala-beta35dbph
4761: pahs-24thiaz-gly-betapy4761: pahs-24thiaz-gly-betapy
4762: dhim-25thioph-ala-betapy 15 4763: bhs-24thioph-bala-betahmo4762: dhim-25thioph-ala-betapy 15 4763: bhs-24thioph-bala-betahmo
4764: bhs-me24oxaz-ala-betaph4764: bhs-me24oxaz-ala-betaph
4765: ibhs-25oxaz-gly-betatbuph4765: ibhs-25oxaz-gly-betatbuph
4766: thpym-26py-gly-betainy14766: thpym-26py-gly-betainy1
4767 : bhs-25methiaz-bala-beta23meoph 20 4768: phhs-24thiaz-bala-betabpy4767: bhs-25methiaz-bala-beta23meoph 20 4768: phhs-24thiaz-bala-betabpy
4769: 2py-53pyrazo-ala-zdap4769: 2py-53pyrazo-ala-zdap
4770 : tolhs-25methiaz-bala-betabpy4770: tolhs-25methiaz-bala-betabpy
4771 : phhs-oxadiaz-bala-betahdcph4771: phhs-oxadiaz-bala-betahdcph
4772 : bhs-24thioph-gly-betamethioph4772: bhs-24thioph-gly-betamethioph
4773: phhs-ithiadiaz-gly-betahdbph4773: phhs-ithiadiaz-gly-betahdbph
25 4774: phhs-25thiaz-gly-zdaptb25 4774: phhs-25thiaz-gly-zdaptb
4775 : bhs-ithiadiaz-gly-betabthioph4775: bhs-ithiadiaz-gly-betabthioph
4776 : bhs-24thioph-bala-beta34dcph4776: bhs-24thioph-bala-beta34dcph
4777: bhs-24thiaz-gly-betahmofu4777: bhs-24thiaz-gly-betahmofu
4778: bhs-25thiaz-bala-betadcphch 30 4779: tolhs-25methiaz-gly-betatbuph4778: bhs-25thiaz-bala-betadcphch 30 4779: tolhs-25methiaz-gly-betatbuph
4780: ibhs-24thiaz-bala-aspaba4780: ibhs-24thiaz-bala-aspaba
4781: thpym-25thiaz-gly-beta35dbph4781: thpym-25thiaz-gly-beta35dbph
4782 : gua-26py-gly-betacph4782: gua-26py-gly-betacph
4783: ibhs-oxadiaz-bala-betadcph 35 4784: ibhs-24thiaz-gly-betainyl4783: ibhs-oxadiaz-bala-betadcph 35 4784: ibhs-24thiaz-gly-betainyl
4785: bim-24py-gly-zdap4785: bim-24py-gly-zdap
4786: 2py-52thiaz-ala-zdap4786: 2py-52thiaz-ala-zdap
4787 : phhs-24thiaz-gly-betal3bendi4787: phhs-24thiaz-gly-betal3bendi
4788: ibhs-ithiadiaz-bala-busu2be4788: ibhs-ithiadiaz-bala-busu2be
4789: bhs-35thioph-ala-betadcph4789: bhs-35thioph-ala-betadcph
40 4790 : phhs-25oxaz-bala-beta34dcph40 4790: phhs-25oxaz-bala-beta34dcph
4791 : bhs-24thiaz-gly-betabthioph4791: bhs-24thiaz-gly-betabthioph
4792: phhs-24thiaz-bala-betaamibe4792: phhs-24thiaz-bala-betaamibe
4793: bhs-24thioph-gly-betadcph4793: bhs-24thioph-gly-betadcph
4794 : tolhs-ithiadiaz-gly-betatbuph 45 4795: ibhs-nme35pyr-bala-betaol4794: tolhs-ithiadiaz-gly-betatbuph 45 4795: ibhs-nme35pyr-bala-betaol
4796 : tolhs-25methiaz-gly-betacbph4796: tolhs-25methiaz-gly-betacbph
4797: phhs-24thiaz-bala-betadmph 4798: tolhs-24thioph-bala-betaipro4797: phhs-24thiaz-bala-betadmph 4798: tolhs-24thioph-bala-betaipro
4799: bhs-25thiaz-ala-betaipro4799: bhs-25thiaz-ala-betaipro
4800: bhs-25thiaz-bala-betaamibe4800: bhs-25thiaz-bala-betaamibe
4801: tolhs-24thiaz-bala-betambiph 5 4802: bhs-triaz-gly-betapy4801: tolhs-24thiaz-bala-betambiph 5 4802: bhs-triaz-gly-betapy
4803: bhs-25oxaz-gly-betathioph4803: bhs-25oxaz-gly-betathioph
4804: bhs-25oxaz-bala-betafu34804: bras-25oxaz-bala-betafu3
4805: ibhs-25oxaz-bala-zdapch4805: ibhs-25oxaz-bala-zdapch
4806: bhs-35thioph-bala-betadcph4806: bras-35thioph-bala-betadcph
4807 : phhs-oxadiaz-bala-betadcphch4807: phhs-oxadiaz-bala-betadcphch
10 4808: phhs-ithiadiaz-bala-asppha10 4808: phhs-ithiadiaz-bala-asppha
4809 : bim-me24thiaz-gly-beta34meoph4809: bim-me24thiaz-gly-beta34meoph
4810: ibhs-25methiaz-gly-betaftrif4810: ibhs-25methiaz-gly-betaftrif
4811: 3pmhs-25methiaz-bala-betapy4811: 3 pmhs-25methiaz-bala-betapy
4812: ibhs-25thiaz-gly-betadhbfu 15 4813: tolhs-24thioph-gly-betaipr4812: ibhs-25thiaz-gly-betadhbfu 15 4813: tolhs-24thioph-gly-betaipr
4814: ibhs-25thiaz-gly-betabmph4814: ibhs-25thiaz-gly-betabmph
4815: bhs-25methiaz-bala-zdaptb4815: bhs-25methiaz-bala-zdaptb
4816: bhs-25thiaz-ala-betaheph4816: bhs-25thiaz-ala-betaheph
4817: bhs-ithiadiaz-bala-betahmph 2o 4818: bim-42pym-gly-betadcph4817: bhs-ithiadiaz-bala-betahmph 2o 4818: bim-42pym-gly-betadcph
4819: bhs-25methiaz-gly-psdap4819: bhs-25methiaz-gly-psdap
4820: phhs-25oxaz-gly-betacph4820: phhs-25oxaz-gly-betacph
4821: bhs-nme35pyr-gly-zdap4821: bhs-nme35pyr-gly-zdap
4822 : bhs-oxadiaz-bala-beta34meoph4822: bhs-oxadiaz-bala-beta34meoph
4823: tolhs-me24thiaz-leu-betapy4823: tolhs-me24thiaz-leu-betapy
25 4824: ibhs-25oxaz-bala-betahc25 4824: ibhs-25oxaz-bala-betahc
4825: bhs-25methiaz-bala-betahmph4825: bhs-25methiaz-bala-betahmph
4826: ibhs-24thiaz-bala-zdapch4826: ibhs-24thiaz-bala-zdapch
4827 : tolhs-25methiaz-gly-betadmph4827: tolhs-25methiaz-gly-betadmph
4828: 2py-26py-gly-betadcph 30 4829: dhim-24thiaz-ala-betadcph4828: 2py-26py-gly-betadcph 30 4829: dhim-24thiaz-ala-betadcph
4830: bhs-24thiaz-ala-betacph4830: bhs-24thiaz-ala-betacph
4831 : phhs-ithiadiaz-bala-aspibua4831: phhs-ithiadiaz-bala-aspibua
4832: bhs-25thiaz-ala-betahph4832: bhs-25thiaz-ala-betahph
4833: phhs-24thioph-bala-betahdcph 35 4834: bhs-24thiaz-nmgly-betathioph4833: phhs-24thioph-bala-betahdcph 35 4834: bhs-24thiaz-nmgly-betathioph
4835: tolhs-ithiadiaz-gly-asppha4835: tolhs-ithiadiaz-gly-asppha
4836 : ibhs-24thioph-gly-betaphethioa4836: ibhs-24thioph-gly-betaphethioa
4837: phhs-24thiaz-bala-psdap4837: phhs-24thiaz-bala-psdap
4838: phhs-25oxaz-bala-betathio34838: phhs-25oxaz-bala-betathio3
4839: ibhs-24thioph-gly-betatbuph4839: ibhs-24thioph-gly-betatbuph
40 4840 : ibhs-nme35pyr-gly-betadcphee40 4840: ibhs-nme35pyr-gly-betadcphee
4841: phhs-me24thiaz-bala-zdap4841: phhs-me24thiaz-bala-zdap
4842 : ibhs-24thioph-bala-betahdbph4842: ibhs-24thioph-bala-betahdbph
4843: tolhs-25thiaz-bala-betaipr4843: tolhs-25thiaz-bala-betaipr
4844 : gua-26py-gly-betabenfu 45 4845: ibhs-oxadiaz-bala-betadtrif4844: gua-26py-gly-betabenfu 45 4845: ibhs-oxadiaz-bala-betadtrif
4846: dhim-24thiaz-gly-betahcbph4846: dhim-24thiaz-gly-betahcbph
4847: dhim-25thiaz-ala-betadcph 4848: tolhs-24thioph-gly-betabnaphth4847: dhim-25thiaz-ala-betadcph 4848: tolhs-24thioph-gly-betabnaphth
4849: bhs-24thiaz-bala-betahmo4849: bras-24thiaz-bala-betahmo
4850: ibhs-oxadiaz-bala-betadbph4850: ibhs-oxadiaz-bala-betadbph
4851: phhs-25methiaz-bala-betahmo 5 4852: ibhs-25methiaz-gly-betapy4851: phhs-25methiaz-bala-betahmo 5 4852: ibhs-25methiaz-gly-betapy
4853: tolhs-25methiaz-gly-zdapch4853: tolhs-25methiaz-gly-zdapch
4854: phhs-25oxaz-bala-betahcbph4854: phhs-25oxaz-bala-betahcbph
4855: tolhs-nme35pyr-bala-betaet4855: tolhs-nme35pyr-bala-betet
4856 : tolhs-ithiadiaz-bala-betapytb4856: tolhs-ithiadiaz-bala-betapytb
4857: nmhs-24thiaz-gly-betadcph4857: nmhs-24thiaz-gly-betadcph
10 4858: phhs-25thiaz-gly-betaibph10 4858: phhs-25thiaz-gly-betaibph
4859: tolhs-24thiaz-bala-betabph4859: tolhs-24thiaz-bala-betabph
4860: tolhs-25oxaz-bala-betaanaphth4860: tolhs-25oxaz-bala-betaanaphth
4861 : bhs-24thioph-bala-betabthioph4861: bhs-24thioph-bala-betabthioph
4862: phhs-oxadiaz-gly-betadmoph 15 4863: bim-me25oxaz-ala-psdap4862: phhs-oxadiaz-gly-betadmoph 15 4863: bim-me25oxaz-ala-psdap
4864 : ibhs-25methiaz-bala-betahdbph4864: ibhs-25methiaz-bala-betahdbph
4865: bhs-24thioph-ala-betacph4865: bhs-24thioph-ala-betacph
4866 : ibhs-24thioph-bala-betadhbfu4866: ibhs-24thioph-bala-betadhbfu
4867: ibhs-nme35pyr-bala-betaipr 2o 4868: bim-25oxaz-bala-zdap4867: ibhs-nme35pyr-bala-betaipr 2o 4868: bim-25oxaz-bala-zdap
4869: bim-42nmeim-leu-zdap 4870: ibhs-oxadiaz-gly-betahdbph 4871 : phhs-me24oxaz-ala-beta34meoph 4872: bhs-oxadiaz-bala-betahmo 4873: phhs-24thiaz-bala-betadhbfu4869: bim-42nmeim-leu-zdap 4870: ibhs-oxadiaz-gly-betahdbph 4871: phhs-me24oxaz-ala-beta34meoph 4872: bhs-oxadiaz-bala-betahmo 4873: phhs-24thiaz-bala-betadhbfu
25 4874: bhs-25fur-bala-zdap 4875 : tolhs-me25thioph-gly-betapy 4876: ibhs-25thiaz-gly-betafph 4877: 2py-me24thiaz-bala-betapy 4878: phhs-ithiadiaz-bala-beta4bph 30 4879: phhs-me25thioph-gly-zdap 4880 : ibhs-24thioph-bala-betapytb 4881: dhim-26py-gly-betadcph 4882 : phhs-25methiaz-gly-betaoxope 4883: bhs-25thiaz-bala-betapy 35 4884: bim-25thiaz-gly-betapbiph 4885: phhs-25thiaz-bala-betahb 4886: bhs-ithiadiaz-gly-beta3quin 4887 : ibhs-25thiaz-gly-betacthioph 4888: bhs-25methiaz-bala-ibsdap 4889: bim-42pym-ala-betainyl25 4874: bhs-25fur-bala-zdap 4875: tolhs-me25thioph-gly-betapy 4876: ibhs-25thiaz-gly-betafph 4877: 2py-me24thiaz-bala-betapy 4878: phhs-ithiadiaz-bala-beta4bph 30 4879: phhs -me25thioph-gly-zdap 4880: ibhs-24thioph-bala-betapytb 4881: dhim-26py-gly-betadcph 4882: phhs-25methiaz-gly-betaoxope 4883: bhs-25thiaz-bala-betapy 35 4884: bim-25thiaz-gly -betapbiph 4885: phhs-25thiaz-bala-betahb 4886: bhs-ithiadiaz-gly-beta3quin 4887: ibhs-25thiaz-gly-betacthioph 4888: bhs-25methiaz-bala-ibsdap 4889: bim-42pym-ala-betainyl
40 4890: bhs-24thiaz-bala-betapym 4891: bim-25thiaz-bala-csdap 4892: bhs-25oxaz-gly-betamesu 4893: bhs-24thioph-ala-betahmph 4894 : ibhs-25methiaz-bala-betahcbph 45 4895: tolhs-ithiadiaz-bala-psdapch 4896: tolhs-24thiaz-gly-betampy 4897: bhs-triaz-bala-psdap 4898 : bhs-nme35pyr-gly-betabnaphth 4899 : phhs-oxadiaz-bala-betabnaphth 4900 : tolhs-25thiaz-bala-betamethioph 4901: tolhs-oxadiaz-gly-betadbph 4902: tolhs-nme35pyr-bala-betadhbfu 4903: bhs-24thiaz-ala-betaanaphth 4904 : ibhs-25thiaz-gly-betadcphch 4905: bhs-oxadiaz-gly-betapbiph 4906: ibhs-ithiadiaz-gly-betampy 4907: tolhs-25thiaz-gly-aspaba40 4890: bhs-24thiaz-bala-betapym 4891: bim-25thiaz-bala-csdap 4892: bhs-25oxaz-gly-betamesu 4893: bhs-24thioph-ala-betahmph 4894: ibhs-25methiaz-bala-betahcbph 45 4895: tolhs -ithiadiaz-bala-psdapch 4896: tolhs-24thiaz-gly-betampy 4897: bhs-triaz-bala-psdap 4898: bhs-nme35pyr-gly-betabnaphth 4899: phhs-oxadiaz-bala-betabnaphth 4900: tolhs-25thiaz-bala-betamethioph 4901: tolhs-oxadiaz-gly-betadbph 4902: tolhs-nme35pyrh-bals-24a-betad -ala-betaanaphth 4904: ibhs-25thiaz-gly-betadcphch 4905: bhs-oxadiaz-gly-betapbiph 4906: ibhs-ithiadiaz-gly-betampy 4907: tolhs-25thiaz-gly-aspaba
10 4908: bhs-nme35pyr-bala-betabdimo 4909 : tolhs-oxadiaz-gly-betadcphtb 4910 : tolhs-oxadiaz-bala-beta3quin 4911: bim-oxadiaz-bala-psdap 4912 : phhs-25methiaz-bala-beta34meoph 15 4913: phhs-24thiaz-gly-betaftrif 4914: bhs-nme35pyr-gly-betacbph 4915: ibhs-oxadiaz-bala-suabu 4916: bhs-triaz-bala-betadcph 4917: 2py-24oxaz-leu-betapy10 4908: bhs-nme35pyr-bala-betabdimo 4909: tolhs-oxadiaz-gly-betadcphtb 4910: tolhs-oxadiaz-bala-beta3quin 4911: bim-oxadiaz-bala-psdap 4912: phhs-25methiaz-bala-beta34mehs 15 4913 -24thiaz-gly-betaftrif 4914: bhs-nme35pyr-gly-betacbph 4915: ibhs-oxadiaz-bala-suabu 4916: bhs-triaz-bala-betadcph 4917: 2py-24oxaz-leu-betapy
20 4918: dhim-42pym-ala-betainyl 4919: phhs-25oxaz-gly-betaftrif 4920 : tolhs-25thiaz-bala-betaanaphth 4921: bhs-thiadiaz-bala-psdap 4922 : tolhs-24thioph-bala-betainyl 4923 : tolhs-25oxaz-gly-betathioph20 4918: dhim-42pym-ala-betainyl 4919: phhs-25oxaz-gly-betaftrif 4920: tolhs-25thiaz-bala-betaanaphth 4921: bhs-thiadiaz-bala-psdap 4922: tolhs-24thioph-bala-betainyl 4923: tolhs- 25oxaz-gly-betathioph
25 4924: bhs-42pym-ala-betapy 4925: 2py-26py-gly-beta23meoph 4926: phhs-ithiadiaz-gly-betahph 4927: phhs-25methiaz-gly-betapym25 4924: bhs-42pym-ala-betapy 4925: 2py-26py-gly-beta23meoph 4926: phhs-ithiadiaz-gly-betahph 4927: phhs-25methiaz-gly-betapym
4928: ibhs-25methiaz-bala-betacthioph 30 4929: bhs-24thiaz-gly-betabenfu4928: ibhs-25methiaz-bala-betacthioph 30 4929: bhs-24thiaz-gly-betabenfu
4930 : tolhs-25thiaz-bala-betaphethioa 4931: bhs-25thiaz-gly-ibsdap 4932: ibhs-25thiaz-bala-betainyl 4933 : tolhs-24thioph-bala-psdaptb4930: tolhs-25thiaz-bala-betaphethioa 4931: bhs-25thiaz-gly-ibsdap 4932: ibhs-25thiaz-bala-betainyl 4933: tolhs-24thioph-bala-psdaptb
35 4934: ibhs-24thiaz-bala-betadhbfu35 4934: ibhs-24thiaz-bala-betadhbfu
4935: bhs-nme35pyr-bala-betaoxope 4936: tolhs-25methiaz-gly-betal3bendi 4937 : ibhs-24thiaz-gly-beta34dcph 4938: bim-me24oxaz-ala-zdap 4939: phhs-nme35pyr-bala-betapbiph4935: bhs-nme35pyr-bala-betaoxope 4936: tolhs-25methiaz-gly-betal3bendi 4937: ibhs-24thiaz-gly-beta34dcph 4938: bim-me24oxaz-ala-zdap 4939: phhs-nme35pyr-bala-betapbiph
40 4940: dhim-26py-ala-betadcph40 4940: dhim-26py-ala-betadcph
4941 : phhs-25methiaz-gly-betacthioph 4942: 2py-42nmeim-bala-zdap 4943: ibhs-25thiaz-gly-betahbcph 4944: ibhs-25thiaz-gly-betacph 45 4945: ibhs-25oxaz-gly-betacbph 4946 : tolhs-25thiaz-bala-betadcph 4947: dhim-24oxaz-gly-betameph 4948: bhs-nme35pyr-gly-betatrif 4949: bhs-24thioph-bala-betahph 4950: bhs-nme35pyr-bala-aspibua 4951: bhs-25thiaz-gly-betamesu 5 4952: bim-me24oxaz-bala-betaph 4953: bhs-25oxaz-bala-betahb 4954: bim-ithiadiaz-ala-zdap4941: phhs-25methiaz-gly-betacthioph 4942: 2py-42nmeim-bala-zdap 4943: ibhs-25thiaz-gly-betahbcph 4944: ibhs-25thiaz-gly-betacph 45 4945: ibhs-25oxaz-gly-betacbph 4946: tolhs- 25thiaz-bala-betadcph 4947: dhim-24oxaz-gly-betameph 4948: bhs-nme35pyr-gly-betatrif 4949: bhs-24thioph-bala-betahph 4950: bhs-nme35pyr-bala-aspibua 4951: bhs-25thiaz-gly-betamesu 5 4952: bim-me24oxaz-bala-betaph 4953: bhs- 25oxaz-bala-betahb 4954: bim-ithiadiaz-ala-zdap
4955: phhs-oxadiaz-bala-betabmph4955: phhs-oxadiaz-bala-betabmph
4956: bhs-oxadiaz-ala-betadito4956: bras-oxadiaz-ala-betadito
4957 : phhs-ithiadiaz-bala-betatbuph4957: phhs-ithiadiaz-bala-betatbuph
4958: bhs-25oxaz-nmgly-betaipro4958: bhs-25oxaz-nmgly-betaipro
4959: 2py-25fur-leu-psdap4959: 2py-25fur-leu-psdap
4960: bhs-ithiadiaz-gly-asppha4960: bhs-ithiadiaz-gly-asppha
4961: ibhs-25methiaz-gly-psdapch4961: ibhs-25methiaz-gly-psdapch
4962: tolhs-25thiaz-gly-psdap 15 4963: bhs-oxadiaz-bala-betaet4962: tolhs-25thiaz-gly-psdap 15 4963: bhs-oxadiaz-bala-betaet
4964 : bhs-24thioph-bala-betamethioph4964: bhs-24thioph-bala-betamethioph
4965: bim-24thioph-gly-aspibua4965: bim-24thioph-gly-aspibua
4966: phhs-me25thioph-ala-betaph4966: phhs-me25thioph-ala-betaph
4967: tolhs-nme35pyr-gly-ibsdap 20 4968: ibhs-24thioph-bala-beta23meoph4967: tolhs-nme35pyr-gly-ibsdap 20 4968: ibhs-24thioph-bala-beta23meoph
4969 : tolhs-oxadiaz-bala-betadhbfu4969: tolhs-oxadiaz-bala-betadhbfu
4970: 2py-25thiaz-gly-betadito4970: 2py-25thiaz-gly-betadito
4971: phhs-ithiadiaz-gly-betahc4971: phhs-ithiadiaz-gly-betahc
4972 : phhs-24thioph-bala-betahbcph4972: phhs-24thioph-bala-betahbcph
4973 : bhs-25methiaz-bala-betah35dc4973: bras-25methiaz-bala-betah35dc
4974: gua-25thioph-gly-betacph4974: gua-25thioph-gly-betacph
4975 : phhs-oxadiaz-gly-beta23meoph4975: phhs-oxadiaz-gly-beta23meoph
4976 : ibhs-24thioph-gly-betah35dc4976: ibhs-24thioph-gly-betah35dc
4977 : phhs-24thioph-gly-betaanaphth4977: phhs-24thioph-gly-betaanaphth
4978: bim-24thiaz-bala-csdap 30 4979: 2py-24thiaz-gly-betameph4978: bim-24thiaz-bala-csdap 30 4979: 2py-24thiaz-gly-betameph
4980 : tolhs-24thioph-bala-betambiph4980: tolhs-24thioph-bala-betambiph
4981: 2py-24im-leu-betadcph4981: 2py-24im-leu-betadcph
4982 : tolhs-nme35pyr-bala-betah35dc4982: tolhs-nme35pyr-bala-betah35dc
4983: bhs-25oxaz-gly-ibsdap 35 4984: ibhs-25methiaz-gly-ibsdap4983: bhs-25oxaz-gly-ibsdap 35 4984: ibhs-25methiaz-gly-ibsdap
4985 : tolhs-ithiadiaz-gly-betameph4985: tolhs-ithiadiaz-gly-betameph
4986: bhs-24thiaz-bala-betainyl4986: bhs-24thiaz-bala-betainyl
4987 : bim-me25thiaz-bala-betadcph4987: bim-me25thiaz-bala-betadcph
4988: tolhs-25methiaz-bala-beta35dbph4988: tolhs-25methiaz-bala-beta35dbph
4989: bhs-me25oxaz-gly-betaph 40 4990: phhs-25thiaz-gly-betadhbfu4989: bhs-me25oxaz-gly-betaph 40 4990: phhs-25thiaz-gly-betadhbfu
4991: cima-42nmeim-bala-betapy4991: cima-42nmeim-bala-betapy
4992 : phhs-24thiaz-bala-betabthioph4992: phhs-24thiaz-bala-betabthioph
4993: bim-24thioph-leu-psdap4993: bim-24thioph-leu-psdap
4994 : tolhs-me25oxaz-bala-beta34meoph 45 4995: ibhs-oxadiaz-bala-betainyl4994: tolhs-me25oxaz-bala-beta34meoph 45 4995: ibhs-oxadiaz-bala-betainyl
4996 : ibhs-ithiadiaz-bala-betaipr4996: ibhs-ithiadiaz-bala-betaipr
4997: tolhs-nme35pyr-bala-betatos 4998: 3pmhs-25thioph-gly-betapy 4999: 2py-25thiaz-gly-aspaba 5000: bim-25methiaz-leu-betapy 5001: bim-24thiaz-bala-betadcph 5002: bhs-24thioph-gly-ibsdap 5003 : 2py-53pyrazo-gly-psdap 5004: ibhs-24thioph-gly-betaamibe 5005: tolhs-me24thiaz-gly-betapy 5006: bhs-52thiaz-gly-betameph 5007 : ibhs-ithiadiaz-bala-betathioph4997: tolhs-nme35pyr-bala-betatos 4998: 3 pmhs-25thioph-gly-betapy 4999: 2py-25thiaz-gly-aspaba 5000: bim-25methiaz-leu-betapy 5001: bim-24thiaz-bala-betadcph 5002: bhs-24thioph-gly-ibsdap 5003: 2py-53pyrazo -gly-psdap 5004: ibhs-24thioph-gly-betaamibe 5005: tolhs-me24thiaz-gly-betapy 5006: bhs-52thiaz-gly-betameph 5007: ibhs-ithiadiaz-bala-betathioph
10 5008: ibhs-25thiaz-gly-betadmph 5009: bim-24im-gly-zdap 5010: ibhs-24thioph-bala-psdaptb 5011: bim-24thioph-bala-aspibua 5012: bhs-ithiadiaz-nmgly-betahmph10 5008: ibhs-25thiaz-gly-betadmph 5009: bim-24im-gly-zdap 5010: ibhs-24thioph-bala-psdaptb 5011: bim-24thioph-bala-aspibua 5012: bhs-ithiadiaz-nmgly-betahmph
15 5013: bhs-25thiaz-bala-betainyl 5014 : phhs-25methiaz-gly-betacbph 5015: bim-25thiaz-gly-betainyl 5016: phhs-24thioph-gly-betabediox 5017 : phhs-oxadiaz-gly-betabnaphth15 5013: bhs-25thiaz-bala-betainyl 5014: phhs-25methiaz-gly-betacbph 5015: bim-25thiaz-gly-betainyl 5016: phhs-24thioph-gly-betabediox 5017: phhs-oxadiaz-gly-betabnaphth
20 5018: ibhs-nme35pyr-gly-betabediox 5019: phhs-25thiaz-bala-betah35dc 5020: tolhs-nme35pyr-bala-beta34meoph 5021: phhs-me24thiaz-gly-psdap 5022 : phhs-24thioph-bala-betabdimo 5023: tolhs-nme35pyr-gly-betaipro20 5018: ibhs-nme35pyr-gly-betabediox 5019: phhs-25thiaz-bala-betah35dc 5020: tolhs-nme35pyr-bala-beta34meoph 5021: phhs-me24thiaz-gly-psdap 5022: phhs-24thioph-bala-betabolhimo 50 nme35pyr-gly-betaipro
25 5024 : ibhs-25thiaz-gly-betaomebendi 5025: phhs-25oxaz-gly-betabmph 5026: dhim-26py-ala-betainyl 5027: thpym-26py-gly-betacbph 5028: ibhs-24thiaz-bala-betapytb25 5024: ibhs-25thiaz-gly-betaomebendi 5025: phhs-25oxaz-gly-betabmph 5026: dhim-26py-ala-betainyl 5027: thpym-26py-gly-betacbph 5028: ibhs-24thiaz-bala-betapytb
30 5029: ibhs-25thiaz-bala-betaimid 5030: ibhs-ithiadiaz-gly-betaol 5031: ibhs-oxadiaz-bala-beta34dcph 5032: phhs-me25oxaz-gly-betaph 5033 : tolhs-24thioph-bala-betafphe30 5029: ibhs-25thiaz-bala-betaimid 5030: ibhs-ithiadiaz-gly-betaol 5031: ibhs-oxadiaz-bala-beta34dcph 5032: phhs-me25oxaz-gly-betaph 5033: tolhs-24thioph-bala-betafphe
35 5034 : ibhs-24thioph-bala-betaftrif 5035: bim-42pym-ala-betapy 5036: bhs-nme35pyr-ala-betacph 5037: tolhs-nme35pyr-gly-betabenfu 5038: bim-42oxaz-ala-zdap 5039: ibhs-25oxaz-bala-betampy35 5034: ibhs-24thioph-bala-betaftrif 5035: bim-42pym-ala-betapy 5036: bhs-nme35pyr-ala-betacph 5037: tolhs-nme35pyr-gly-betabenfu 5038: bim-42oxaz-ala-zdap 5039: ibhs- 25oxaz-bala-betampy
40 5040: phhs-25thiaz-gly-betafphe 5041 : dhim-26py-gly-beta34meoph 5042 : ibhs-24thiaz-gly-betathiome 5043 : bim-me24thioph-bala-betapy 5044: bim-24im-bala-zdap40 5040: phhs-25thiaz-gly-betafphe 5041: dhim-26py-gly-beta34meoph 5042: ibhs-24thiaz-gly-betathiome 5043: bim-me24thioph-bala-betapy 5044: bim-24im-bala-zdap
45 5045: bhs-ithiadiaz-bala-betahbcph 5046: 2py-25thiaz-gly-betadcph 5047: bim-me25oxaz-bala-betadcph 5048: phhs-25methiaz-bala-betathiobe 5049: ibhs-25oxaz-bala-beta3guin 5050 : phhs-oxadiaz-bala-beta34meoph 5051: gua-42pym-gly-betabthioph 5052: bhs-35thioph-bala-betapy 5053: 2py-42pym-gly-betainyl 5054 : phhs-ithiadiaz-gly-beta4bph 5055 : bhs-24thioph-bala-betahdcph 5056: ibhs-25methiaz-bala-betahni 5057: bim-25methiaz-leu-psdap45 5045: bhs-ithiadiaz-bala-betadcph 5046: 2py-25thiaz-gly-betadcph 5047: bim-me25oxaz-bala-betadcph 5048: phhs-25methiaz-bala-betathiobe 5049: ibhs-25oxaz-bala-beta3guin 5050: phhs-oxadiaz-bala-beta34meoph 5051: gua-42pym-gly-betabthioph 5052: bhs-35thioph-bala-betapy 5053: 2py-42p -gly-betainyl 5054: phhs-ithiadiaz-gly-beta4bph 5055: bhs-24thioph-bala-betahdcph 5056: ibhs-25methiaz-bala-betahni 5057: bim-25methiaz-leu-psdap
10 5058: tolhs-me25oxaz-ala-beta34meoph 5059: ibhs-25thiaz-bala-betampy 5060: phhs-25methiaz-gly-betaoxaz 5061: 2pmhs-42pym-gly-betainyl 5062: tolhs-nme35pyr-gly-betapyr10 5058: tolhs-me25oxaz-ala-beta34meoph 5059: ibhs-25thiaz-bala-betampy 5060: phhs-25methiaz-gly-betaoxaz 5061: 2 pmhs-42pym-gly-betainyl 5062: tolhs-nme35pyr-gly-betapyr
15 5063: tolhs-25methiaz-bala-betapych 5064: tolhs-oxadiaz-gly-betadito 5065: tolhs-me25oxaz-ala-psdap 5066 : bhs-ithiadiaz-bala-beta3quin 5067: 2py-25oxaz-ala-psdap15 5063: tolhs-25methiaz-bala-betapych 5064: tolhs-oxadiaz-gly-betadito 5065: tolhs-me25oxaz-ala-psdap 5066: bhs-ithiadiaz-bala-beta3quin 5067: 2py-25oxaz-ala-psdap
20 5068: bim-24thioph-leu-betapy20 5068: bim-24thioph-leu-betapy
5069: tolhs-25methiaz-bala-betahmo 5070: bhs-25methiaz-bala-zdapch 5071: bhs-24thiaz-bala-betamethi 5072 : 2pmhs-24thioph-bala-betamethioph 5073: bim-24thioph-gly-aspaba5069: tolhs-25methiaz-bala-betahmo 5070: bhs-25methiaz-bala-zdapch 5071: bhs-24thiaz-bala-betamethi 5072: 2 pmhs-24thioph-bala-betamethioph 5073: bim-24thioph-gly-aspaba
25 5074 : ibhs-25methiaz-gly-betatrif 5075: bhs-24thioph-gly-beta3quin 5076: ibhs-oxadiaz-gly-betatrif 5077 : 2py-triaz-bala-betapy 5078: phhs-24thioph-bala-betameph25 5074: ibhs-25methiaz-gly-betatrif 5075: bhs-24thioph-gly-beta3quin 5076: ibhs-oxadiaz-gly-betatrif 5077: 2py-triaz-bala-betapy 5078: phhs-24thioph-bala-betameph
30 5079: bim-25oxaz-gly-psdap30 5079: bim-25oxaz-gly-psdap
5080 : tolhs-nme35pyr-bala-betabthioph 5081: tolhs-25thiaz-gly-betahmph 5082: bhs-42nmeim-ala-betapy 5083 : tolhs-25oxaz-bala-beta34meoph5080: tolhs-nme35pyr-bala-betabthioph 5081: tolhs-25thiaz-gly-betahmph 5082: bhs-42nmeim-ala-betapy 5083: tolhs-25oxaz-bala-beta34meoph
35 5084: ibhs-24thiaz-gly-betameph 5085: bim-me24thioph-bala-betadcph 5086: 2py-26py-gly-betabiph 5087: ibhs-25thiaz-bala-betaheph 5088: bhs-25thiaz-nmgly-betadhbfu 5089: tolhs-oxadiaz-gly-betameph35 5084: ibhs-24thiaz-gly-betameph 5085: bim-me24thioph-bala-betadcph 5086: 2py-26py-gly-betabiph 5087: ibhs-25thiaz-bala-betaheph 5088: bhs-25thiaz-nmgly-betadhbfu 5089: tolhs- oxadiaz-gly-betameph
40 5090 : bhs-nme35pyr-nmgly-beta34meoph 5091: dhpyrr-24thiaz-gly-betapy 5092 : tolhs-25oxaz-bala-betathioph 5093: bhs-24thiaz-bala-betaipro 5094: bhs-25oxaz-ala-betamesu40 5090: bhs-nme35pyr-nmgly-beta34meoph 5091: dhpyrr-24thiaz-gly-betapy 5092: tolhs-25oxaz-bala-betathioph 5093: bhs-24thiaz-bala-betaipro 5094: bhs-25oxaz-ala-betamesu
45 5095: ibhs-24thioph-gly-betathiobe 5096: nmhs-25methiaz-gly-betadcph 5097: phhs-24thiaz-gly-aspibua 5098: bhs-oxadiaz-gly-betapytb 5099: bim-24thiaz-bala-psdap 5100 : ibhs-nme35pyr-bala-betabenfu 5101 : ibhs-24thiaz-bala-betaomebendi 5102 : ibhs-25thiaz-bala-betabnaphth 5103: 2py-25oxaz-leu-betapy 5104: phhs-ithiadiaz-gly-aspbzla 5105 : ibhs-25thiaz-bala-betabdimo 5106 : 2py-me24thioph-gly-betadcph 5107 : tolhs-oxadiaz-bala-betaipro45 5095: ibhs-24thioph-gly-betathiobe 5096: nmhs-25methiaz-gly-betadcph 5097: phhs-24thiaz-gly-aspibua 5098: bhs-oxadiaz-gly-betapytb 5099: bim-24thiaz-bala-psdap 5100: ibhs-nme35pyr-bala-betabenfu 5101: ibhs-24thiaz-bala-betaomebendi 5102: ibhs-25thiaz-bala-betabnaphth 2523: 2py -leu-betapy 5104: phhs-ithiadiaz-gly-aspbzla 5105: ibhs-25thiaz-bala-betabdimo 5106: 2py-me24thioph-gly-betadcph 5107: tolhs-oxadiaz-bala-betaipro
10 5108: ibhs-24thiaz-bala-betahmph 5109: bhs-25thiaz-gly-aspaba 5110: 2py-35thioph-ala-betapy 5111: bhs-24thioph-gly-zdaptb 5112: phhs-nme35pyr-gly-betatrif10 5108: ibhs-24thiaz-bala-betahmph 5109: bhs-25thiaz-gly-aspaba 5110: 2py-35thioph-ala-betapy 5111: bhs-24thioph-gly-zdaptb 5112: phhs-nme35pyr-gly-betatrif
15 5113: tolhs-25oxaz-gly-betaphethioa 5114: thazep-24thiaz-gly-betadcph 5115: tolhs-ithiadiaz-gly-betadcphch 5116: phhs-25oxaz-bala-betafbph 5117 : tolhs-25methiaz-gly-betamethioph15 5113: tolhs-25oxaz-gly-betaphethioa 5114: thazep-24thiaz-gly-betadcph 5115: tolhs-ithiadiaz-gly-betadcphch 5116: phhs-25oxaz-bala-betafbph 5117: tolhs-25methiaz-gly-betameth
20 5118: impy-24thiaz-gly-betambiph 5119: phhs-oxadiaz-bala-betafu3 5120: tolhs-me24thiaz-leu-zdap 5121 : ibhs-ithiadiaz-bala-betabediox 5122: bhs-oxadiaz-gly-betahc 5123: tolhs-24thiaz-gly-betahmph20 5118: impy-24thiaz-gly-betambiph 5119: phhs-oxadiaz-bala-betafu3 5120: tolhs-me24thiaz-leu-zdap 5121: ibhs-ithiadiaz-bala-betabediox 5122: bhs-oxadiaz-gly-betahc 5123: tolhs- 24thiaz-gly-betahmph
25 5124: bhs-oxadiaz-bala-zdap 5125: bhs-oxadiaz-bala-betahbcph 5126: bim-24thiaz-gly-psdap 5127: bhs-24thiaz-ala-betampy 5128: 2pmhs-25oxaz-gly-beta35dbph25 5124: bhs-oxadiaz-bala-zdap 5125: bhs-oxadiaz-bala-betahbcph 5126: bim-24thiaz-gly-psdap 5127: bhs-24thiaz-ala-betampy 5128: 2 pmhs-25oxaz-gly-beta35dbph
30 5129: bhs-26py-gly-betainyl30 5129: bhs-26py-gly-betainyl
5130 : bhs-nme35pyr-bala-betapym 5131: 2py-26py-met-zdap 5132 : ibhs-25oxaz-bala-betacthioph 5133 : impy-24thioph-gly-betabthioph5130: bhs-nme35pyr-bala-betapym 5131: 2py-26py-met-zdap 5132: ibhs-25oxaz-bala-betacthioph 5133: impy-24thioph-gly-betabthioph
35 5134: tolhs-oxadiaz-gly-betahdcph 5135: bhs-24thiaz-gly-betapych 5136: bhs-oxadiaz-ala-psdap 5137 : phhs-24thiaz-gly-betadcphee 5138: phhs-oxadiaz-gly-betaibph 5139: ibhs-25oxaz-bala-betadhbfu35 5134: tolhs-oxadiaz-gly-betahdcph 5135: bhs-24thiaz-gly-betapych 5136: bhs-oxadiaz-ala-psdap 5137: phhs-24thiaz-gly-betadcphee 5138: phhs-oxadiaz-gly-betahph 5139: 25oxaz-bala-betadhbfu
40 5140 : ibhs-25thiaz-bala-betathiobe 5141: bhs-nme35pyr-ala-betadcph 5142: bhs-25oxaz-bala-betampy 5143: 2py-26py-ala-betainyl 5144 : tolhs-25oxaz-bala-betal3bendi40 5140: ibhs-25thiaz-bala-betathiobe 5141: bhs-nme35pyr-ala-betadcph 5142: bhs-25oxaz-bala-betampy 5143: 2py-26py-ala-betainyl 5144: tolhs-25oxaz-bala-betal3bendi
45 5145: tolhs-nme35pyr-bala-betahmo 5146: bhs-nme35pyr-gly-betadbph 5147: bim-me25thioph-bala-psdap 5148: bhs-25oxaz-ala-beta34dcph 5149: ibhs-nme35pyr-gly-zdaptb45 5145: tolhs-nme35pyr-bala-betahmo 5146: bhs-nme35pyr-gly-betadbph 5147: bim-me25thioph-bala-psdap 5148: bhs-25oxaz-ala-beta34dcph 5149: ibhs-nme35pyr-gly-zdaptb
5150: tolhs-25methiaz-bala-betamethi5150: tolhs-25methiaz-bala-betamethi
5151 : bhs-nme35pyr-gly-betal3bendi 5 5152: 2py-me25thioph-leu-psdap5151: bhs-nme35pyr-gly-betal3bendi 5 5152: 2py-me25thioph-leu-psdap
5153 : ibhs-24thioph-bala-betatbuph5153: ibhs-24thioph-bala-betatbuph
5154: sabhs-24thiaz-gly-psdap5154: sabhs-24thiaz-gly-psdap
5155: bhs-25thiaz-bala-betahmph5155: bras-25thiaz-bala-betahmph
5156: bim-triaz-gly-betapy5156: bim-triaz-gly-betapy
5157 : phhs-24thioph-bala-betamethioph5157: phhs-24thioph-bala-betamethioph
10 5158: phhs-nme35pyr-bala-psdaptb10 5158: phhs-nme35pyr-bala-psdaptb
5159: dhim-24py-gly-betameph5159: dhim-24py-gly-betameph
5160: cima-25thiaz-bala-psdap5160: cima-25thiaz-bala-psdap
5161: bhs-24thiaz-gly-betampy5161: bhs-24thiaz-gly-betampy
5162 : tolhs-25methiaz-bala-beta23meoph 15 5163: 2py-ithiadiaz-ala-betapy5162: tolhs-25methiaz-bala-beta23meoph 15 5163: 2py-ithiadiaz-ala-betapy
5164 : impy-25methiaz-gly-betabthioph5164: impy-25methiaz-gly-beta thioph
5165 : ibhs-24thioph-bala-betaoxope5165: ibhs-24thioph-bala-betaoxope
5166: tolhs-me25thiaz-gly-beta34meoph5166: tolhs-me25thiaz-gly-beta34meoph
5167: ibhs-nme35pyr-gly-betamethi 20 5168: ibhs-nme35pyr-gly-betabpy5167: ibhs-nme35pyr-gly-betamethi 20 5168: ibhs-nme35pyr-gly-betabpy
5169: tolhs-25methiaz-bala-betaph5169: tolhs-25methiaz-bala-betaph
5170: tolhs-24thioph-gly-betapyr5170: tolhs-24thioph-gly-betapyr
5171: ibhs-25oxaz-bala-betahph5171: ibhs-25oxaz-bala-betahph
5172: bim-24thiaz-bala-betafphe5172: bim-24thiaz-bala-betafphe
5173 : tolhs-me24thioph-gly-betadcph5173: tolhs-me24thioph-gly-betadcph
25 5174: bhs-ithiadiaz-gly-psdapch25 5174: bhs-ithiadiaz-gly-psdapch
5175: 2py-24thiaz-bala-betapy5175: 2py-24thiaz-bala-betapy
5176: tolhs-nme35pyr-bala-betaipro5176: tolhs-nme35pyr-bala-betaipro
5177 : bhs-24thioph-nmgly-beta23meoph5177: bhs-24thioph-nmgly-beta23meoph
5178: bim-52thiaz-gly-betadcph 30 5179: gua-24oxaz-gly-betathioph5178: bim-52thiaz-gly-betadcph 30 5179: gua-24oxaz-gly-betathioph
5180: bhs-triaz-gly-betadcph5180: bras-triaz-gly-betadcph
5181: bim-42nmeim-bala-betaipr5181: bim-42nmeim-bala-betaipr
5182: tolhs-25thiaz-gly-betapym5182: tolhs-25thiaz-gly-betapym
5183 : phhs-25thiaz-bala-betadcphch 35 5184: phhs-ithiadiaz-gly-betafu25183: phhs-25thiaz-bala-betadcphch 35 5184: phhs-ithiadiaz-gly-betafu2
5185: phhs-ithiadiaz-bala-betampy5185: phhs-ithiadiaz-bala-betampy
5186 : phhs-ithiadiaz-gly-betadcphtb5186: phhs-ithiadiaz-gly-betadcphtb
5187: dhim-26py-ala-betapy5187: dhim-26py-ala-betapy
5188: phhs-oxadiaz-gly-betamesu5188: phhs-oxadiaz-gly-betamesu
5189 : ibhs-25methiaz-bala-psdapee5189: ibhs-25methiaz-bala-psdapee
40 5190: phhs-me24thioph-gly-zdap40 5190: phhs-me24thioph-gly-zdap
5191: ibhs-25oxaz-gly-betadmph5191: ibhs-25oxaz-gly-betadmph
5192 : bhs-25methiaz-gly-betadcphee5192: bhs-25methiaz-gly-betadcphee
5193: bim-oxadiaz-ala-psdap5193: bim-oxadiaz-ala-psdap
5194: phhs-ithiadiaz-gly-betaamibe 45 5195: 2py-me25oxaz-gly-betaph5194: phhs-ithiadiaz-gly-betaamibe 45 5195: 2py-me25oxaz-gly-betaph
5196: phhs-25oxaz-bala-aspaba5196: phhs-25oxaz-bala-aspaba
5197: bim-me25oxaz-leu-zdap 5198: 2py-25thiaz-bala-betafluo 5199: ibhs-24thioph-gly-betafphe 5200: bim-25thiaz-bala-betapy 5201: bhs-24thioph-bala-betatos 5202: gua-25thiaz-gly-betabdimo 5203: 2py-42oxaz-ala-betadcph 5204 : bhs-ithiadiaz-gly-betamethioph 5205: tolhs-me25thioph-leu-betapy 5206: bhs-25thiaz-ala-psdap 5207 : ibhs-25thiaz-bala-betaoxope5197: bim-me25oxaz-leu-zdap 5198: 2py-25thiaz-bala-betafluo 5199: ibhs-24thioph-gly-betafphe 5200: bim-25thiaz-bala-betapy 5201: bhs-24thioph-bala-betatos 5202: gua-25thiaz-gly-betabdimo 5203: 2py-42oxaz -ala-betadcph 5204: bhs-ithiadiaz-gly-betamethioph 5205: tolhs-me25thioph-leu-betapy 5206: bhs-25thiaz-ala-psdap 5207: ibhs-25thiaz-bala-betaoxope
10 5208: bhs-25oxaz-bala-betahmph 5209: bhs-25thiaz-gly-betabthioph 5210: tolhs-24thioph-gly-betabenfu 5211: phhs-me25thioph-leu-betaph 5212: tolhs-25thiaz-gly-ibsdap10 5208: bhs-25oxaz-bala-betahmph 5209: bhs-25thiaz-gly-betabthioph 5210: tolhs-24thioph-gly-betabenfu 5211: phhs-me25thioph-leu-betaph 5212: tolhs-25thiaz-gly-ibsdap
15 5213: phhs-24thioph-gly-betahni 5214: bhs-24thioph-gly-betaipr 5215: tolhs-me25oxaz-ala-betapy 5216: phhs-me24thioph-bala-zdap 5217 : bhs-25oxaz-bala-betathioph15 5213: phhs-24thioph-gly-betahni 5214: bhs-24thioph-gly-betaipr 5215: tolhs-me25oxaz-ala-betapy 5216: phhs-me24thioph-bala-zdap 5217: bhs-25oxaz-bala-betathioph
20 5218: ibhs-ithiadiaz-gly-zdaptb 5219: ibhs-24thioph-bala-betahmo 5220 : tolhs-25methiaz-gly-betabthioph 5221 : tolhs-nme35pyr-gly-betaibph 5222: tolhs-me24thioph-gly-zdap 5223: phhs-24thiaz-gly-ibsdap20 5218: ibhs-ithiadiaz-gly-zdaptb 5219: ibhs-24thioph-bala-betahmo 5220: tolhs-25methiaz-gly-betabthioph 5221: tolhs-nme35pyr-gly-betaibph 5222: tolhs-me24thioph-gly-zdap 5223: 24thiaz-gly-ibsdap
25 5224: tolhs-25thiaz-gly-betahbcph 5225: ibhs-oxadiaz-bala-betafph 5226: bhs-oxadiaz-nmgly-betahmph 5227: impy-42nmeim-bala-betameph 5228: gua-25thiaz-gly-betadcph25 5224: tolhs-25thiaz-gly-betahbcph 5225: ibhs-oxadiaz-bala-betafph 5226: bhs-oxadiaz-nmgly-betahmph 5227: impy-42nmeim-bala-betameph 5228: gua-25thiaz-gly-betadcph
30 5229: phhs-oxadiaz-gly-betapym 5230: bhs-24thioph-gly-betabmph 5231: phhs-24thioph-gly-aspibua 5232: bhs-25oxaz-ala-betahph 5233: ibhs-24thiaz-gly-asppha30 5229: phhs-oxadiaz-gly-betapym 5230: bhs-24thioph-gly-betabmph 5231: phhs-24thioph-gly-aspibua 5232: bhs-25oxaz-ala-betahph 5233: ibhs-24thiaz-gly-asppha
35 5234: 2py-42oxaz-gly-zdap 5235: phhs-me24thiaz-gly-beta34meoph 5236: bhs-nme35pyr-bala-betarnethi 5237: bhs-25oxaz-bala-betaheph 5238: dhim-25thiaz-ala-betameph 5239 : bhs-ithiadiaz-gly-beta35dbph35 5234: 2py-42oxaz-gly-zdap 5235: phhs-me24thiaz-gly-beta34meoph 5236: bhs-nme35pyr-bala-betarnethi 5237: bhs-25oxaz-bala-betaheph 5238: dhim-25thiaz-ala-betameph 5239: bhs- ithiadiaz-gly-beta35dbph
40 5240: bim-oxadiaz-ala-betapy 5241: ibhs-nme35pyr-bala-betafu3 5242: phhs-ithiadiaz-gly-betabpy 5243 : tolhs-ithiadiaz-gly-betah35dc 5244: 2py-me25thiaz-ala-psdap40 5240: bim-oxadiaz-ala-betapy 5241: ibhs-nme35pyr-bala-betafu3 5242: phhs-ithiadiaz-gly-betabpy 5243: tolhs-ithiadiaz-gly-betah35dc 5244: 2py-me25thiaz-ala-psdap
45 5245: bim-24im-ala-zdap 5246 : bim-me25oxaz-gly-beta34meoph 5247: bhs-oxadiaz-bala-betapbiph 5248: bhs-24thioph-gly-beta4bph45 5245: bim-24im-ala-zdap 5246: bim-me25oxaz-gly-beta34meoph 5247: bhs-oxadiaz-bala-betapbiph 5248: bhs-24thioph-gly-beta4bph
5249 : ibhs-25methiaz-bala-betaibph5249: ibhs-25methiaz-bala-betaibph
5250 : ibhs-24thiaz-gly-betatbuph5250: ibhs-24thiaz-gly-betatbuph
5251 : bhs-oxadiaz-nmgly-betaanaphth 5 5252: phhs-25thiaz-gly-betamethi5251: bhs-oxadiaz-nmgly-betaanaphth 5 5252: phhs-25thiaz-gly-betamethi
5253 : ibhs-ithiadiaz-gly-betadcphtb5253: ibhs-ithiadiaz-gly-betadcphtb
5254: tolhs-24thioph-bala-betaet5254: tolhs-24thioph-bala-betet
5255: bhs-25methiaz-bala-beta34meoph5255: bhs-25methiaz-bala-beta34meoph
5256: ibhs-25thiaz-bala-suabu5256: ibhs-25thiaz-bala-suabu
5257: 2py-42nmeim-gly-betapy5257: 2py-42nmeim-gly-betapy
5258: tolhs-25thiaz-bala-betahmph5258: tolhs-25thiaz-bala-betahmph
5259: bhs-25thiaz-gly-betahni5259: bhs-25thiaz-gly-betahni
5260 : 2pmhs-42nmeim-bala-betaphethio5260: 2 pmhs-42nmeim-bala-betaphethio
5261 : tolhs-25methiaz-gly-betadbph5261: tolhs-25methiaz-gly-betadbph
5262 : ibhs-25thiaz-gly-betamethioph 15 5263: bhs-25thiaz-nmala-betameph5262: ibhs-25thiaz-gly-betamethioph 15 5263: bhs-25thiaz-nmala-betameph
5264 : 2py-25methiaz-ala-betadcph5264: 2py-25methiaz-ala-betadcph
5265 : bim-35fur-gly-betadcph5265: bim-35fur-gly-betadcph
5266: bhs-oxadiaz-gly-betabenfu5266: bhs-oxadiaz-gly-betabenfu
5267: 2py-oxadiaz-gly-betadcph 20 5268: bhs-25oxaz-bala-betaph5267: 2py-oxadiaz-gly-betadcph 20 5268: bhs-25oxaz-bala-betaph
5269 : phhs-24thioph-gly-betamethioph5269: phhs-24thioph-gly-betamethioph
5270: phhs-oxadiaz-bala-betafu25270: phhs-oxadiaz-bala-betafu2
5271: bhs-25methiaz-gly-betaoxaz5271: bhs-25methiaz-gly-betaoxaz
5272 : tolhs-25thiaz-bala-betacbph5272: tolhs-25thiaz-bala-betacbph
5273: tolhs-25oxaz-gly-betah35dc5273: tolhs-25oxaz-gly-betah35dc
5274: ibhs-24thiaz-gly-aspaba5274: ibhs-24thiaz-gly-aspaba
5275: bim-25oxaz-bala-aspbzla5275: bim-25oxaz-bala-aspbzla
5276 : tolhs-oxadiaz-bala-betahmofu5276: tolhs-oxadiaz-bala-betahmofu
5277 : bhs-25oxaz-bala-csdap5277: bras-25oxaz-bala-csdap
5278: tolhs-oxadiaz-gly-zdaptb 30 5279: phhs-25thiaz-bala-beta34dcph5278: tolhs-oxadiaz-gly-zdaptb 30 5279: phhs-25thiaz-bala-beta34dcph
5280: phhs-24thioph-bala-betambiph5280: phhs-24thioph-bala-betambiph
5281 : tolhs-24thiaz-gly-betabthioph5281: tolhs-24thiaz-gly-betabthioph
5282 : bhs-24thiaz-bala-betaomebendi5282: bhs-24thiaz-bala-betaomebendi
5283: phhs-25thiaz-bala-beta35dbph 35 5284: ibhs-25methiaz-bala-aspbzla5283: phhs-25thiaz-bala-beta35dbph 35 5284: ibhs-25methiaz-bala-aspbzla
5285 : bhs-24thioph-ala-beta23meoph5285: bhs-24thioph-ala-beta23meoph
5286 : bhs-nme35pyr-bala-csdap5286: bhs-nme35pyr-bala-csdap
5287: phhs-24thiaz-bala-betafu35287: phhs-24thiaz-bala-betafu3
5288 : ibhs-25methiaz-gly-betaimid5288: ibhs-25methiaz-gly-betaimid
5289 : ibhs-24thiaz-gly-betafph 405289: ibhs-24thiaz-gly-betafph 40
5290 : ιmpy-25oxaz-bala-betabenf5290: ιmpy-25oxaz-bala-betabenf
5291 : bhs-25thiaz-bala-suabu5291: bras-25thiaz-bala-suabu
5292 : phhs-24thioph-gly-betabdimo5292: phhs-24thioph-gly-betabdimo
5293 : tolhs-me24thioph-bala-psdap5293: tolhs-me24thioph-bala-psdap
5294: ibhs-24thioph-gly-betabenfu5294: ibhs-24thioph-gly-betabenfu
45 5295: bim-35fur-ala-betapy45 5295: bim-35fur-ala-betapy
5296: bhs-25oxaz-bala-suabu5296: bras-25oxaz-bala-suabu
5297: bhs-25thiaz-bala-betamethi 5298 : bhs-oxadiaz-bala-betabpy5297: bhs-25thiaz-bala-betamethi 5298: bras-oxadiaz-bala-betabpy
5299 : gua-24thiaz-gly-betaamibe5299: gua-24thiaz-gly-betaamibe
5300 : bhs-25methiaz-bala-betathioph5300: bhs-25methiaz-bala-betathioph
5301 : phhs-me25thiaz-gly-betadcph 5 5302: bhs-24thiaz-bala-ibsdap5301: phhs-me25thiaz-gly-betadcph 5 5302: bhs-24thiaz-bala-ibsdap
5303 : ibhs-25thiaz-bala-aspaba5303: ibhs-25thiaz-bala-aspaba
5304 : tolhs-ithiadiaz-bala-betaheph5304: tolhs-ithiadiaz-bala-betaheph
5305: bhs-25oxaz-nmgly-betahph5305: bhs-25oxaz-nmgly-betahph
5306: tolhs-24thioph-gly-betaol5306: tolhs-24thioph-gly-betaol
5307 : bhs-25methiaz-bala-betapych5307: bras-25methiaz-bala-betapych
10 5308: 2py-42nmeim-bala-betaomebendi10 5308: 2py-42nmeim-bala-betaomebendi
5309 : bhs-25methiaz-bala-betabthioph5309: bhs-25methiaz-bala-betabthioph
5310: bhs-25thiaz-bala-betaimid5310: bhs-25thiaz-bala-betaimide
5311: tolhs-24thiaz-gly-betahb5311: tolhs-24thiaz-gly-betahb
5312 : ibhs-ithiadiaz-bala-betacph 15 5313: ibhs-25oxaz-gly-asppha5312: ibhs-ithiadiaz-bala-betacph 15 5313: ibhs-25oxaz-gly-asppha
5314 : phhs-25thiaz-gly-betahdbph5314: phhs-25thiaz-gly-betahdbph
5315: tolhs-ithiadiaz-gly-betacthioph5315: tolhs-ithiadiaz-gly-betacthioph
5316 : bhs-ithiadiaz-ala-betal3bendi5316: bhs-ithiadiaz-ala-betal3bendi
5317: tolhs-25oxaz-gly-betabph 20 5318: ibhs-25thiaz-bala-betaomebendi5317: tolhs-25oxaz-gly-betabph 20 5318: ibhs-25thiaz-bala-betaomebendi
5319: bhs-ithiadiaz-gly-ibsdap5319: bhs-ithiadiaz-gly-ibsdap
5320: ibhs-24thiaz-gly-betapyee5320: ibhs-24thiaz-gly-betapyee
5321: tolhs-24thioph-bala-betathiobe5321: tolhs-24thioph-bala-betathiobe
5322: bhs-ithiadiaz-gly-betapyee5322: bhs-ithiadiaz-gly-betapyee
5323: ibhs-24thioph-gly-betadito5323: ibhs-24thioph-gly-betadito
25 5324 : bim-me24oxaz-leu-beta34meoph25 5324: bim-me24oxaz-leu-beta34meoph
5325: tolhs-24thiaz-bala-busu2be5325: tolhs-24thiaz-bala-busu2be
5326: bhs-25thiaz-gly-betaoxaz5326: bhs-25thiaz-gly-betaoxaz
5327: ibhs-nme35pyr-gly-aspaba5327: ibhs-nme35pyr-gly-aspaba
5328: ibhs-nme35pyr-bala-betatrif 30 5329: bhs-25oxaz-bala-betafph5328: ibhs-nme35pyr-bala-betatrif 30 5329: bhs-25oxaz-bala-betafph
5330: tolhs-25oxaz-bala-betacbph5330: tolhs-25oxaz-bala-betacbph
5331: 2py-oxadiaz-ala-betadcph5331: 2py-oxadiaz-ala-betadcph
5332: phhs-24thiaz-bala-busu2be5332: phhs-24thiaz-bala-busu2be
5333 : tolhs-25methiaz-gly-betainyl 35 5334: phhs-nme35pyr-bala-betafu35333: tolhs-25methiaz-gly-betainyl 35 5334: phhs-nme35pyr-bala-betafu3
5335: bhs-24thiaz-gly-betaphethioa5335: bhs-24thiaz-gly-betaphethioa
5336 : ibhs-25oxaz-gly-aspibua5336: ibhs-25oxaz-gly-aspibua
5337 : tolhs-24thiaz-gly-betaphethioa5337: tolhs-24thiaz-gly-betaphethioa
5338: 2py-25methiaz-gly-beta35dbph5338: 2py-25methiaz-gly-beta35dbph
5339: ibhs-nme35pyr-gly-betahb5339: ibhs-nme35pyr-gly-betahb
40 5340: 2py-25thiaz-bala-betadcph40 5340: 2py-25thiaz-bala-betadcph
5341: 2py-me24thioph-leu-zdap5341: 2py-me24thioph-leu-zdap
5342 : phhs-nme35pyr-gly-betaipr5342: phhs-nme35pyr-gly-betaipr
5343: bhs-25oxaz-nmgly-betacph5343: bhs-25oxaz-nmgly-betacph
5344 : tolhs-oxadiaz-bala-beta4bph 45 5345: bhs-24thioph-ala-betadcph5344: tolhs-oxadiaz-bala-beta4bph 45 5345: bhs-24thioph-ala-betadcph
5346 : phhs-25thiaz-gly-betal3bendi5346: phhs-25thiaz-gly-betal3bendi
5347: tolhs-oxadiaz-gly-suabu 5348 : bhs-25oxaz-bala-betapyee5347: tolhs-oxadiaz-gly-suabu 5348: bhs-25oxaz-bala-betapyee
5349: tolhs-25thiaz-bala-aspbzla5349: tolhs-25thiaz-bala-aspbzla
5350 : tolhs-24thiaz-gly-betahcbph5350: tolhs-24thiaz-gly-betahcbph
5351: ibhs-oxadiaz-bala-betatrif 5 5352: bhs-24thiaz-bala-zdap5351: ibhs-oxadiaz-bala-betatrif 5 5352: bhs-24thiaz-bala-zdap
5353 : ibhs-ithiadiaz-bala-betapyee5353: ibhs-ithiadiaz-bala-betapyee
5354: 2py-42nmeim-leu-betadcph5354: 2py-42nmeim-leu-betadcph
5355 : bim-42pym-gly-betameph5355: bim-42pym-gly-betameph
5356: tolhs-25oxaz-gly-betafph5356: tolhs-25oxaz-gly-betafph
5357 : phhs-25oxaz-bala-betahmo5357: phhs-25oxaz-bala-betahmo
10 5358: bhs-25thioph-ala-betainyl10 5358: bhs-25thioph-ala-betainyl
5359: phhs-25methiaz-gly-betaftrif5359: phhs-25methiaz-gly-betaftrif
5360: bim-25oxaz-bala-betapy5360: bim-25oxaz-bala-betapy
5361 : ibhs-nme35pyr-gly-betaol5361: ibhs-nme35pyr-gly-betaol
5362 : 2py-25methiaz-gly-betatbuph 15 5363: bhs-25thiaz-bala-betadmoph5362: 2py-25methiaz-gly-betatbuph 15 5363: bhs-25thiaz-bala-betadmoph
5364: tolhs-24thioph-bala-csdap5364: tolhs-24thioph-bala-csdap
5365 : ibhs-oxadiaz-gly-betal3bendi5365: ibhs-oxadiaz-gly-betal3bendi
5366 : tolhs-nme35pyr-gly-betampy5366: tolhs-nme35pyr-gly-betampy
5367: bhs-25oxaz-bala-betaoxaz 20 5368: bhs-nme35pyr-nmgly-betafphe5367: bhs-25oxaz-bala-betaoxaz 20 5368: bhs-nme35pyr-nmgly-betafphe
5369: tolhs-nme35pyr-bala-betadcph5369: tolhs-nme35pyr-bala-betadcph
5370: tolhs-nme35pyr-bala-betadmoph5370: tolhs-nme35pyr-bala-betadmoph
5371: 2py-25thiaz-gly-betapy5371: 2py-25thiaz-gly-betapy
5372: dhim-42pym-ala-betameph5372: dhim-42pym-ala-betameph
5373: bhs-24thiaz-bala-betapy5373: bhs-24thiaz-bala-betapy
25 5374: phhs-oxadiaz-bala-betaimid25 5374: phhs-oxadiaz-bala-betaimide
5375: ibhs-ithiadiaz-gly-betahmph5375: ibhs-ithiadiaz-gly-betahmph
5376: tolhs-24thioph-bala-zdapch5376: tolhs-24thioph-bala-zdapch
5377: 2py-24oxaz-ala-psdap5377: 2py-24oxaz-ala-psdap
5378 : ibhs-ithiadiaz-gly-betambiph 30 5379: bim-nme35pyr-bala-psdap5378: ibhs-ithiadiaz-gly-betambiph 30 5379: bim-nme35pyr-bala-psdap
5380: bim-25fur-leu-betadcph5380: bim-25fur-leu-betadcph
5381: bhs-oxadiaz-bala-psdap5381: bras-oxadiaz-bala-psdap
5382: phhs-25methiaz-bala-betaipr5382: phhs-25methiaz-bala-betaipr
5383: bhs-me25thiaz-ala-zdap 35 5384: ibhs-ithiadiaz-bala-betameph5383: bhs-me25thiaz-ala-zdap 35 5384: ibhs-ithiadiaz-bala-betameph
5385: bhs-25oxaz-gly-betal3bendi5385: bhs-25oxaz-gly-betal3bendi
5386 : tolhs-nme35pyr-bala-betabdimo5386: tolhs-nme35pyr-bala-betabdimo
5387: ibhs-oxadiaz-bala-betahc5387: ibhs-oxadiaz-bala-betahc
5388: bhs-25oxaz-bala-beta34dcph5388: bhs-25oxaz-bala-beta34dcph
5389 : ibhs-25thiaz-bala-betadhbfu5389: ibhs-25thiaz-bala-betadhbfu
40 5390: bhs-25methiaz-gly-betatrif40 5390: bras-25methiaz-gly-betatrif
5391 : ibhs-24thiaz-bala-betafu25391: ibhs-24thiaz-bala-betafu2
5392 : phhs-ithiadiaz-gly-betabediox5392: phhs-ithiadiaz-gly-betabediox
5393: bhs-me25thioph-gly-betapy5393: bhs-me25thioph-gly-betapy
5394: bhs-me25oxaz-ala-betadcph 45 5395: bhs-24thiaz-gly-betaphethio5394: bhs-me25oxaz-ala-betadcph 45 5395: bhs-24thiaz-gly-betaphethio
5396 : tolhs-24thiaz-bala-betadtrif5396: tolhs-24thiaz-bala-betadtrif
5397 : bhs-ithiadiaz-nmgly-betaanaphth 5398: phhs-24thiaz-bala-betadcphtb5397: bhs-ithiadiaz-nmgly-betaanaphth 5398: phhs-24thiaz-bala-betadcphtb
5399: bhs-ithiadiaz-ala-betacph5399: bhs-ithiadiaz-ala-betacph
5400: thpym-24thioph-bala-psdap5400: thpym-24thioph-bala-psdap
5401: bhs-25oxaz-ala-betathioph 5 5402: bim-25methiaz-nmala-betadcph5401: bhs-25oxaz-ala-betathioph 5 5402: bim-25methiaz-nmala-betadcph
5403: tolhs-25methiaz-gly-betahc5403: tolhs-25methiaz-gly-betahc
5404: bhs-25py-gly-betapy5404: bhs-25py-gly-betapy
5405: bim-me24thiaz-leu-zdap5405: bim-me24thiaz-leu-zdap
5406: ibhs-oxadiaz-bala-betapyee5406: ibhs-oxadiaz-bala-betapyee
5407: phhs-me25oxaz-bala-betaph5407: phhs-me25oxaz-bala-betaph
1010
5408: phhs-ithiadiaz-bala-betahmofu5408: phhs-ithiadiaz-bala-betahmofu
5409: ibhs-25oxaz-bala-betafbph5409: ibhs-25oxaz-bala-betafbph
5410: phhs-ithiadiaz-gly-betabmph5410: phhs-ithiadiaz-gly-betabmph
5411 : phhs-25thiaz-gly-betabthioph5411: phhs-25thiaz-gly-betabthioph
5412: ibhs-25methiaz-gly-aspibua 15 5413: tolhs-25thiaz-gly-psdapee5412: ibhs-25methiaz-gly-aspibua 15 5413: tolhs-25thiaz-gly-psdapee
5414: bim-25thioph-ala-psdap5414: bim-25thioph-ala-psdap
5415 : bhs-ithiadiaz-nmgly-beta23meoph5415: bhs-ithiadiaz-nmgly-beta23meoph
5416: bhs-24thiaz-gly-betahb5416: bhs-24thiaz-gly-betahb
5417: tolhs-25thiaz-gly-betamethi 20 5418: tolhs-oxadiaz-bala-betapych5417: tolhs-25thiaz-gly-betamethi 20 5418: tolhs-oxadiaz-bala-betapych
5419: bim-25methiaz-ala-psdap5419: bim-25methiaz-ala-psdap
5420: bhs-me24oxaz-leu-betapy5420: bhs-me24oxaz-leu-betapy
5421 : tolhs-25methiaz-gly-beta4bph5421: tolhs-25methiaz-gly-beta4bph
5422: dhim-26py-gly-betapy5422: dhim-26py-gly-betapy
5423 : ibhs-oxadiaz-gly-asppha5423: ibhs-oxadiaz-gly-asppha
25 5424: 2py-24thiaz-leu-betadcph25 5424: 2py-24thiaz-leu-betadcph
5425: tolhs-oxadiaz-bala-betabmph5425: tolhs-oxadiaz-bala-betabmph
5426: bhs-oxadiaz-bala-betafu25426: bras-oxadiaz-bala-betafu2
5427 : bhs-25methiaz-bala-betaipro5427: bhs-25methiaz-bala-betaipro
5428 : tolhs-25methiaz-gly-betapych 30 5429: phhs-25thiaz-bala-beta4bph5428: tolhs-25methiaz-gly-betapych 30 5429: phhs-25thiaz-bala-beta4bph
5430: bim-thiadiaz-leu-betadcph5430: bim-thiadiaz-leu-betadcph
5431: tolhs-24thiaz-gly-betabmph5431: tolhs-24thiaz-gly-betabmph
5432 : gua-42pym-gly-betaheph5432: gua-42pym-gly-betaheph
5433 : phhs-ithiadiaz-bala-betaipr 35 5434: 2pmhs-25thiaz-bala-betapyr5433: phhs-ithiadiaz-bala-betaipr 35 5434: 2 pmhs-25thiaz-bala-betapyr
5435 : tolhs-me24thioph-leu-betadcph5435: tolhs-me24thioph-leu-betadcph
5436: bhs-oxadiaz-gly-betamethi5436: bhs-oxadiaz-gly-betamethi
5437 : phhs-24thiaz-bala-betathiome5437: phhs-24thiaz-bala-betathiome
5438 : ibhs-nme35pyr-bala-betarnethioph5438: ibhs-nme35pyr-bala-betarnethioph
5439: tolhs-me24thiaz-ala-psdap5439: tolhs-me24thiaz-ala-psdap
40 5440 : tolhs-24thioph-gly-betadito40 5440: tolhs-24thioph-gly-betadito
5441: bhs-24thiaz-bala-betahdcph5441: bras-24thiaz-bala-betahdcph
5442 : phhs-24thiaz-gly-betathiobe5442: phhs-24thiaz-gly-betathiobe
5443 : bim-42pym-ala-betameph5443: bim-42pym-ala-betameph
5444: phhs-24thiaz-gly-zdaptb 45 5445: bhs-24thiaz-gly-csdap5444: phhs-24thiaz-gly-zdaptb 45 5445: bhs-24thiaz-gly-csdap
5446: bhs-oxadiaz-bala-betadtrif5446: bras-oxadiaz-bala-betadtrif
5447: 2py-42oxaz-ala-psdap 5448: phhs-oxadiaz-bala-beta4bph 5449 : bhs-oxadiaz-gly-betahdbph 5450: gua-26py-gly-beta4bph 5451: bhs-26pyrazi-ala-betapy 5452: tolhs-24thiaz-gly-psdaptb 5453: bhs-42nmeim-gly-betaheρh 5454 : ibhs-ithiadiaz-bala-betatbuph 5455: ibhs-24thioph-bala-betatrif 5456 : phhs-25methiaz-gly-betaph 5457: bim-me24thioph-bala-zdap5447: 2py-42oxaz-ala-psdap 5448: phhs-oxadiaz-bala-beta4bph 5449: bhs-oxadiaz-gly-betahdbph 5450: gua-26py-gly-beta4bph 5451: bhs-26pyrazi-ala-betapy 5452: tolhs-24thiaz-gly-psdaptb 5453: bhs-42n -gly-betaheρh 5454: ibhs-ithiadiaz-bala-betatbuph 5455: ibhs-24thioph-bala-betatrif 5456: phhs-25methiaz-gly-betaph 5457: bim-me24thioph-bala-zdap
10 5458 : ibhs-oxadiaz-bala-betabthioph 5459: bhs-me24oxaz-leu-psdap 5460: tolhs-24thiaz-gly-betapych 5461: phhs-25thiaz-gly-betaol 5462: bhs-me24im-gly-zdap10 5458: ibhs-oxadiaz-bala-betabthioph 5459: bhs-me24oxaz-leu-psdap 5460: tolhs-24thiaz-gly-betapych 5461: phhs-25thiaz-gly-betaol 5462: bhs-me24im-gly-zdap
15 5463: bim-25oxaz-gly-betathiome 5464 : impy-25oxaz-bala-betaamibe 5465: tolhs-25methiaz-bala-asppha 5466 : ibhs-24thioph-bala-betahdcph 5467 : ibhs-25methiaz-bala-busu2be15 5463: bim-25oxaz-gly-betathiome 5464: impy-25oxaz-bala-betaamibe 5465: tolhs-25methiaz-bala-asppha 5466: ibhs-24thioph-bala-betahdcph 5467: ibhs-25methiaz-bala-busu2be
2o 5468: bhs-24thiaz-bala-betabmph 5469: bhs-me25thioph-gly-psdap 5470: ibhs-24thiaz-bala-betafluo 5471: dhim-24thiaz-ala-betapy 5472: bim-25thioph-leu-betadcph 5473: thpym-24thiaz-bala-psdap2o 5468: bhs-24thiaz-bala-betabmph 5469: bhs-me25thioph-gly-psdap 5470: ibhs-24thiaz-bala-betafluo 5471: dhim-24thiaz-ala-betapy 5472: bim-25thioph-leu-betadcph 5473: thpym- 24thiaz-bala-psdap
25 5474: bhs-25oxaz-bala-betameph 5475: bhs-24thiaz-gly-betaoxaz 5476: bim-24thiaz-ala-psdap 5477: phhs-24thiaz-bala-betaoxaz 5478: bhs-ithiadiaz-bala-betahb25 5474: bhs-25oxaz-bala-betameph 5475: bhs-24thiaz-gly-betaoxaz 5476: bim-24thiaz-ala-psdap 5477: phhs-24thiaz-bala-betaoxaz 5478: bhs-ithiadiaz-bala-betahb
30 5479: bhs-ithiadiaz-bala-zdapee 5480: bhs-25oxaz-nmgly-betaoxaz 5481: bhs-25thiaz-nmgly-betadito 5482: bhs-nme35pyr-gly-psdapch 5483: ibhs-nme35pyr-gly-betadbph30 5479: bhs-ithiadiaz-bala-zdapee 5480: bhs-25oxaz-nmgly-betaoxaz 5481: bhs-25thiaz-nmgly-betadito 5482: bhs-nme35pyr-gly-psdapch 5483: ibhs-nme35pyr-gly-betadbph
35 5484: phhs-me24oxaz-leu-zdap 5485: bhs-oxadiaz-bala-betaoxaz 5486: bhs-oxadiaz-gly-betadito 5487: gua-42pym-gly-betathiobe 5488: bim-42nmeim-ala-betadcph 5489: bhs-42nmeim-gly-betabnaphth35 5484: phhs-me24oxaz-leu-zdap 5485: bhs-oxadiaz-bala-betaoxaz 5486: bhs-oxadiaz-gly-betadito 5487: gua-42pym-gly-betathiobe 5488: bim-42nmeim-ala-betadcph 5489: bhs- 42nmeim-gly-betabnaphth
40 5490 : phhs-ithiadiaz-bala-betapytb 5491: 2py-ithiadiaz-bala-aspbzla 5492: bhs-24thioph-gly-betafbph 5493 : bhs-oxadiaz-bala-betaanaphth 5494: bhs-me24oxaz-bala-betaph40 5490: phhs-ithiadiaz-bala-betapytb 5491: 2py-ithiadiaz-bala-aspbzla 5492: bhs-24thioph-gly-betafbph 5493: bhs-oxadiaz-bala-betaanaphth 5494: bhs-me24oxaz-bala-betaph
45 5495: phhs-25thiaz-bala-betacthioph 5496 : tolhs-25methiaz-bala-betapyee 5497: bhs-25methiaz-gly-beta35dbph 5498: phhs-me24oxaz-gly-betapy45 5495: phhs-25thiaz-bala-betacthioph 5496: tolhs-25methiaz-bala-betapyee 5497: bhs-25methiaz-gly-beta35dbph 5498: phhs-me24oxaz-gly-betapy
5499: ibhs-25methiaz-bala-betaph5499: ibhs-25methiaz-bala-betaph
5500: 2py-24oxaz-bala-betapy5500: 2py-24oxaz-bala-betapy
5501: ibhs-ithiadiaz-gly-aspibua 5 5502: phhs-25thiaz-gly-betadcphee5501: ibhs-ithiadiaz-gly-aspibua 5 5502: phhs-25thiaz-gly-betadcphee
5503: bhs-24pym-gly-zdap5503: bhs-24pym-gly-zdap
5504 : tolhs-24thiaz-gly-betathioph5504: tolhs-24thiaz-gly-betathioph
5505 : tolhs-ithiadiaz-bala-betadcphch5505: tolhs-ithiadiaz-bala-betadcphch
5506: 2py-ithiadiaz-leu-betadcph5506: 2py-ithiadiaz-leu-betadcph
5507: phhs-24thiaz-bala-betapyee5507: phhs-24thiaz-bala-betapyee
10 5508 : phhs-ithiadiaz-bala-betadcph10 5508: phhs-ithiadiaz-bala-betadcph
5509 : bhs-25oxaz-bala-betarnethioph5509: bras-25oxaz-bala-betarnethioph
5510: 2py-53pyrazo-leu-betapy5510: 2py-53pyrazo-leu-betapy
5511: ibhs-25oxaz-gly-betadcph5511: ibhs-25oxaz-gly-betadcph
5512 : ibhs-oxadiaz-gly-csdap 15 5513: bim-25methiaz-ala-betadcph5512: ibhs-oxadiaz-gly-csdap 15 5513: bim-25methiaz-ala-betadcph
5514 : phhs-25methiaz-bala-betamethioph5514: phhs-25methiaz-bala-betamethioph
5515: bhs-oxadiaz-bala-psdaptb5515: bras-oxadiaz-bala-psdaptb
5516: 2py-me25thiaz-gly-betapy5516: 2py-me25thiaz-gly-betapy
5517: tolhs-25thiaz-gly-betacph 20 5518: impy-42nmeim-gly-betapyr5517: tolhs-25thiaz-gly-betacph 20 5518: impy-42nmeim-gly-betapyr
5519 : bim-25methiaz-bala-betafphe5519: bim-25methiaz-bala-betafphe
5520: phhs-25oxaz-gly-betapytb5520: phhs-25oxaz-gly-betapytb
5521: ibhs-25oxaz-gly-betapbiph5521: ibhs-25oxaz-gly-betapbiph
5522: 2py-me25oxaz-bala-psdap5522: 2py-me25oxaz-bala-psdap
5523 : bhs-ithiadiaz-bala-zdaptb5523: bhs-ithiadiaz-bala-zdaptb
25 5524 : 2py-25methiaz-bala-betafluo25 5524: 2py-25methiaz-bala-betafluo
5525 : bhs-25thiaz-gly-betacthioph5525: bhs-25thiaz-gly-betacthioph
5526: bhs-nme35pyr-bala-beta35dbph5526: bhs-nme35pyr-bala-beta35dbph
5527: bhs-25oxaz-bala-betadcph5527: bras-25oxaz-bala-betadcph
5528: tolhs-25thiaz-gly-betahdbph 30 5529: phhs-25thiaz-bala-betafph5528: tolhs-25thiaz-gly-betahdbph 30 5529: phhs-25thiaz-bala-betafph
5530: bhs-25thiaz-bala-betahdcph5530: bras-25thiaz-bala-betahdcph
5531: bhs-ithiadiaz-gly-betafu35531: bhs-ithiadiaz-gly-betafu3
5532: bhs-25thiaz-bala-betapym5532: bras-25thiaz-bala-betapym
5533 : bhs-ithiadiaz-ala-beta23meoph 35 5534: ibhs-nme35pyr-bala-betapych5533: bhs-ithiadiaz-ala-beta23meoph 35 5534: ibhs-nme35pyr-bala-betapych
5535: bhs-me25oxaz-bala-betapy5535: bhs-me25oxaz-bala-betapy
5536: 2py-nme35pyr-bala-asppha5536: 2py-nme35pyr-bala-asppha
5537: 2py-35thioph-bala-betapy5537: 2py-35thioph-bala-betapy
5538: phhs-nme35pyr-bala-betadcphee5538: phhs-nme35pyr-bala-betadcphee
5539: tolhs-25oxaz-bala-betabpy5539: tolhs-25oxaz-bala-betabpy
40 5540 : bhs-24thioph-bala-betacthioph40 5540: bhs-24thioph-bala-betacthioph
5541: bhs-24thioph-ala-betabpy5541: bhs-24thioph-ala-betabpy
5542: bim-24im-leu-betadcph5542: bim-24im-leu-betadcph
5543 : bhs-oxadiaz-gly-betamesu5543: bras-oxadiaz-gly-betamesu
5544: bhs-thiadiaz-gly-betadcph 45 5545: tolhs-25thiaz-bala-betameph5544: bhs-thiadiaz-gly-betadcph 45 5545: tolhs-25thiaz-bala-betameph
5546 : bhs-thiadiaz-ala-psdap5546: bhs-thiadiaz-ala-psdap
5547 : bhs-24thioph-bala-betadcphch 5548 : bhs-ithiadiaz-gly-betabenfu5547: bras-24thioph-bala-betadcphch 5548: bhs-ithiadiaz-gly-betabenfu
5549 : ibhs-nme35pyr-bala-betadcph.ee5549: ibhs-nme35pyr-bala-betadcph.ee
5550: bhs-me25oxaz-leu-betaph5550: bhs-me25oxaz-leu-betaph
5551: bhs-me24thiaz-leu-betadcph 5 5552: tolhs-25thiaz-gly-betatbuph5551: bhs-me24thiaz-leu-betadcph 5 5552: tolhs-25thiaz-gly-betatbuph
5553: gua-25thioph-gly-betacbph5553: gua-25thioph-gly-betacbph
5554: phhs-25methiaz-gly-betahph5554: phhs-25methiaz-gly-betahph
5555: 2py-me25thiaz-bala-psdap5555: 2py-me25thiaz-bala-psdap
5556: bhs-25methiaz-nmgly-betabpy5556: bhs-25methiaz-nmgly-betabpy
5557: bhs-oxadiaz-nmgly-betameph5557: bhs-oxadiaz-nmgly-betameph
10 5558: tolhs-24thiaz-gly-betacthioph10 5558: tolhs-24thiaz-gly-betacthioph
5559 : dimethpym-24thioph-gly-betameph5559: dimethpym-24thioph-gly-betameph
5560: ibhs-25oxaz-bala-betameph5560: ibhs-25oxaz-bala-betameph
5561: bhs-24thioph-bala-aspbzla5561: bhs-24thioph-bala-aspbzla
5562 : ibhs-24thioph-bala-betabediox 15 5563: tolhs-25oxaz-bala-betaphethioa5562: ibhs-24thioph-bala-betabediox 15 5563: tolhs-25oxaz-bala-betaphethioa
5564: ibhs-24thiaz-gly-betabpy5564: ibhs-24thiaz-gly-betabpy
5565: tolhs-25oxaz-bala-betacthJoph5565: tolhs-25oxaz-bala-betacthJoph
5566 : tolhs-24thioph-bala-betapbiph5566: tolhs-24thioph-bala-betapbiph
5567 : ibhs-oxadiaz-bala-betahbcph 20 5568: phhs-oxadiaz-bala-betatrif5567: ibhs-oxadiaz-bala-betahbcph 20 5568: phhs-oxadiaz-bala-betatrif
5569: bhs-25oxaz-bala-betabmph5569: bras-25oxaz-bala-betabmph
5570: ibhs-oxadiaz-gly-betameph5570: ibhs-oxadiaz-gly-betameph
5571 : phhs-ithiadiaz-bala-betathiome5571: phhs-ithiadiaz-bala-betathiome
5572 : tolhs-ithiadiaz-bala-betacthioph5572: tolhs-ithiadiaz-bala-betacthioph
5573 : phhs-24thiaz-bala-betaftrif5573: phhs-24thiaz-bala-betaftrif
25 5574 : ibhs-ithiadiaz-bala-betamethi25 5574: ibhs-ithiadiaz-bala-betamethi
5575 : ibhs-ithiadiaz-gly-betabenfu5575: ibhs-ithiadiaz-gly-betabenfu
5576 : ibhs-24thioph-gly-betahdcph5576: ibhs-24thioph-gly-betahdcph
5577 : phhs-me25thioph-bala-betaph5577: phhs-me25thioph-bala-betaph
5578: 2py-oxadiaz-gly-aspbzla 30 5579: bhs-24thiaz-nmgly-betameph5578: 2py-oxadiaz-gly-aspbzla 30 5579: bhs-24thiaz-nmgly-betameph
5580 : tolhs-oxadiaz-bala-betadtrif5580: tolhs-oxadiaz-bala-betadtrif
5581: bhs-oxadiaz-bala-beta3quin5581: bhs-oxadiaz-bala-beta3quin
5582: hs-25thioph-gly-betapy5582: hs-25thioph-gly-betapy
5583 : 2py-53pyrazo-gly-betapy 35 5584: bhs-me25thiaz-leu-beta34meoph5583: 2py-53pyrazo-gly-betapy 35 5584: bhs-me25thiaz-leu-beta34meoph
5585: bgua-25thiaz-gly-betapy5585: bgua-25thiaz-gly-betapy
5586: tolhs-nme35pyr-gly-betahni5586: tolhs-nme35pyr-gly-betahni
5587: tolhs-25thiaz-gly-betafphe5587: tolhs-25thiaz-gly-betafphe
5588: bhs-ithiadiaz-bala-csdap5588: bhs-ithiadiaz-bala-csdap
5589: dhim-24thiaz-gly-betadtrif5589: dhim-24thiaz-gly-betadtrif
40 5590: bim-24thiaz-bala-aspaba40 5590: bim-24thiaz-bala-aspaba
5591: phhs-25thiaz-bala-betaheph5591: phhs-25thiaz-bala-betaheph
5592 : bhs-24thiaz-gly-betal3bendi5592: bhs-24thiaz-gly-betal3bendi
5593 : ibhs-25oxaz-bala-betathioph5593: ibhs-25oxaz-bala-betathioph
5594 : phhs-25methiaz-gly-betafu3 45 5595: tolhs-ithiadiaz-gly-betamethioph5594: phhs-25methiaz-gly-betafu3 45 5595: tolhs-ithiadiaz-gly-betamethioph
5596: 2py-42nmeim-gly-betatos5596: 2py-42nmeim-gly-betatos
5597: ibhs-25oxaz-bala-betapyr 5598: ibhs-nme35pyr-bala-betamethi5597: ibhs-25oxaz-bala-betapyr 5598: ibhs-nme35pyr-bala-betamethi
5599: bhs-24thioph-bala-betaheph5599: bhs-24thioph-bala-betaheph
5600 : ibhs-24thiaz-bala-betadcphtb5600: ibhs-24thiaz-bala-betadcphtb
5601: phhs-25thiaz-gly-betaheph 5 5602: ibhs-nme35pyr-bala-betaphethio5601: phhs-25thiaz-gly-betaheph 5 5602: ibhs-nme35pyr-bala-betaphethio
5603 : ibhs-25methiaz-gly-betathio35603: ibhs-25methiaz-gly-betathio3
5604: tolhs-nme35pyr-gly-betaol5604: tolhs-nme35pyr-gly-betaol
5605: tolhs-24thioph-gly-suabu5605: tolhs-24thioph-gly-suabu
5606: bhs-25oxaz-gly-beta35dbph5606: bhs-25oxaz-gly-beta35dbph
5607: tolhs-24thiaz-gly-aspbzla5607: tolhs-24thiaz-gly-aspbzla
10 5608: bhs-24thioph-nmgly-betameph10 5608: bhs-24thioph-nmgly-betameph
5609 : tolhs-ithiadiaz-bala-betahni5609: tolhs-ithiadiaz-bala-betahni
5610: bhs-25oxaz-gly-busu2be5610: bhs-25oxaz-gly-busu2be
5611 : phhs-me25thioph-gly-beta34meoph5611: phhs-me25thioph-gly-beta34meoph
5612: bhs-24thiaz-gly-betadcphtb 15 5613: bim-26py-gly-betapy5612: bhs-24thiaz-gly-betadcphtb 15 5613: bim-26py-gly-betapy
5614: 2py-me24thiaz-ala-betaph5614: 2py-me24thiaz-ala-betaph
5615: 2py-me24oxaz-bala-betadcph5615: 2py-me24oxaz-bala-betadcph
5616: bhs-25methiaz-gly-betahni5616: bhs-25methiaz-gly-betahni
5617: bhs-25methiaz-gly-betabph 20 5618: bhs-24thiaz-bala-betafphe5617: bhs-25methiaz-gly-betabph 20 5618: bhs-24thiaz-bala-betafphe
5619 : tolhs-ithiadiaz-bala-betafbph5619: tolhs-ithiadiaz-bala-betafbph
5620: ibhs-oxadiaz-gly-betahc5620: ibhs-oxadiaz-gly-betahc
5621: phhs-nme35pyr-bala-betabmph5621: phhs-nme35pyr-bala-betabmph
5622 : bhs-25methiaz-bala-betaimid5622: bhs-25methiaz-bala-betaimide
5623: tolhs-oxadiaz-bala-betadbph5623: tolhs-oxadiaz-bala-betadbph
25 5624 : bhs-25methiaz-gly-beta34dcph25 5624: bhs-25methiaz-gly-beta34dcph
5625 : bhs-ithiadiaz-nmgly-betainyl5625: bhs-ithiadiaz-nmgly-betainyl
5626: bhs-25methiaz-gly-zdap5626: bhs-25methiaz-gly-zdap
5627 : gua-25thioph-gly-betal3bendi5627: gua-25thioph-gly-betal3bendi
5628: phhs-24thiaz-bala-betaibph 30 5629: bhs-24thioph-bala-betarnethi5628: phhs-24thiaz-bala-betaibph 30 5629: bhs-24thioph-bala-betarnethi
5630: bim-me24oxaz-ala-betapy5630: bim-me24oxaz-ala-betapy
5631: phhs-24thioph-bala-betahmo5631: phhs-24thioph-bala-betahmo
5632: ibhs-24thioph-gly-betahmo5632: ibhs-24thioph-gly-betahmo
5633 : tolhs-oxadiaz-bala-betafph 35 5634: ibhs-25oxaz-gly-betafluo5633: tolhs-oxadiaz-bala-betafph 35 5634: ibhs-25oxaz-gly-betafluo
5635: phhs-25thiaz-gly-betaipro5635: phhs-25thiaz-gly-betaipro
5636: 2py-thiadiaz-ala-zdap5636: 2py-thiadiaz-ala-zdap
5637 : tolhs-ithiadiaz-gly-betadcphtb5637: tolhs-ithiadiaz-gly-betadcphtb
5638: ibhs-25thiaz-bala-betahb5638: ibhs-25thiaz-bala-betahb
5639: phhs-me24thioph-gly-betaph5639: phhs-me24thioph-gly-betaph
40 5640: phhs-oxadiaz-gly-betapy40 5640: phhs-oxadiaz-gly-betapy
5641 : tolhs-nme35pyr-gly-betathio35641: tolhs-nme35pyr-gly-betathio3
5642: bhs-25methiaz-gly-betafphe5642: bhs-25methiaz-gly-betafphe
5643: bhs-nme35pyr-bala-betatrif5643: bras-nme35pyr-bala-betatrif
5644: phhs-nme35pyr-bala-betaheph 45 5645: bim-25thiaz-bala-asppha5644: phhs-nme35pyr-bala-betaheph 45 5645: bim-25thiaz-bala-asppha
5646 : 2py-25thiaz-bala-beta34dcph5646: 2py-25thiaz-bala-beta34dcph
5647: bhs-24thiaz-gly-suabu 5648: ibhs-24thioph-bala-betafbph5647: bhs-24thiaz-gly-suabu 5648: ibhs-24thioph-bala-betafbph
5649: tolhs-25thiaz-bala-zdapee5649: tolhs-25thiaz-bala-zdapee
5650 : tolhs-ithiadiaz-bala-ibsdap5650: tolhs-ithiadiaz-bala-ibsdap
5651: bhs-25methiaz-gly-betaphethio 5 5652: ibhs-25oxaz-gly-betapym5651: bhs-25methiaz-gly-betaphethio 5 5652: ibhs-25oxaz-gly-betapym
5653: phhs-25oxaz-bala-betahb5653: phhs-25oxaz-bala-betahb
5654 : ibhs-ithiadiaz-gly-betainyl5654: ibhs-ithiadiaz-gly-betainyl
5655: tolhs-me24thiaz-leu-psdap5655: tolhs-me24thiaz-leu-psdap
5656: ibhs-25oxaz-bala-betathio35656: ibhs-25oxaz-bala-betathio3
5657: 2py-53pyrazo-leu-psdap5657: 2py-53pyrazo-leu-psdap
10 5658: tolhs-nme35pyr-bala-betacph10 5658: tolhs-nme35pyr-bala-betacph
5659: ibhs-25thiaz-bala-betafu25659: ibhs-25thiaz-bala-betafu2
5660 : ibhs-25methiaz-gly-betadcphch5660: ibhs-25methiaz-gly-betadcphch
5661: bhs-me24oxaz-ala-zdap5661: bhs-me24oxaz-ala-zdap
5662 : phhs-24thiaz-bala-beta34meoph 15 5663: tolhs-nme35pyr-bala-betathiobe5662: phhs-24thiaz-bala-beta34meoph 15 5663: tolhs-nme35pyr-bala-betathiobe
5664: phhs-me24thioph-gly-psdap5664: phhs-me24thioph-gly-psdap
5665: tolhs-25oxaz-gly-betabpy5665: tolhs-25oxaz-gly-betabpy
5666: 2py-25oxaz-gly-asppha5666: 2py-25oxaz-gly-asppha
5667 : ibhs-25methiaz-gly-betacbph 20 5668: bhs-25methiaz-bala-beta3quin5667: ibhs-25methiaz-gly-betacbph 20 5668: bhs-25methiaz-bala-beta3quin
5669 : tolhs-24thioph-gly-beta23meoph5669: tolhs-24thioph-gly-beta23meoph
5670 : tolhs-nme35pyr-gly-betahcbph5670: tolhs-nme35pyr-gly-betahcbph
5671: ibhs-25thiaz-bala-betaphethioa5671: ibhs-25thiaz-bala-betaphethioa
5672: phhs-nme35pyr-gly-betafphe5672: phhs-nme35pyr-gly-betafphe
5673 : bhs-ithiadiaz-gly-betabediox5673: bhs-ithiadiaz-gly-betabediox
25 5674: ibhs-24thiaz-gly-betahdbph25 5674: ibhs-24thiaz-gly-betahdbph
5675: tolhs-25methiaz-bala-betathioph5675: tolhs-25methiaz-bala-betathioph
5676 : tolhs-nme35pyr-bala-betamethi5676: tolhs-nme35pyr-bala-betamethi
5677 : tolhs-25thiaz-gly-betabenfu5677: tolhs-25thiaz-gly-betabenfu
5678: gua-24thiaz-gly-betabdimo 30 5679: phhs-24thiaz-bala-psdapee5678: gua-24thiaz-gly-betabdimo 30 5679: phhs-24thiaz-bala-psdapee
5680: phhs-oxadiaz-gly-psdapch5680: phhs-oxadiaz-gly-psdapch
5681: phhs-25oxaz-gly-betahdcph5681: phhs-25oxaz-gly-betahdcph
5682: ibhs-24thioph-bala-betapym5682: ibhs-24thioph-bala-betapym
5683: tolhs-25thiaz-gly-betahb 35 5684: bhs-42nmeim-gly-betaet5683: tolhs-25thiaz-gly-betahb 35 5684: bhs-42nmeim-gly-betet
5685: bim-me25thioph-ala-betapy5685: bim-me25thioph-ala-betapy
5686: bim-25thiaz-leu-betadcph5686: bim-25thiaz-leu-betadcph
5687: bhs-25thiaz-bala-betapyee5687: bhs-25thiaz-bala-betapyee
5688: ibhs-25methiaz-bala-betahmo5688: ibhs-25methiaz-bala-betahmo
5689: phhs-25oxaz-gly-betacbph5689: phhs-25oxaz-gly-betacbph
40 5690: dhim-42pym-ala-zdap40 5690: dhim-42pym-ala-zdap
5691: bhs-oxadiaz-gly-betathioph5691: bhs-oxadiaz-gly-betathioph
5692: tolhs-25oxaz-gly-betahmo5692: tolhs-25oxaz-gly-betahmo
5693: phhs-24thiaz-gly-betaipr5693: phhs-24thiaz-gly-betaipr
5694: tolhs-me24oxaz-leu-betapy 45 5695: phhs-oxadiaz-gly-betapytb5694: tolhs-me24oxaz-leu-betapy 45 5695: phhs-oxadiaz-gly-betapytb
5696 : ibhs-25methiaz-gly-beta35dbph5696: ibhs-25methiaz-gly-beta35dbph
5697: bhs-ithiadiaz-gly-betadhbfu 5698: phhs-25thiaz-gly-busu2be5697: bhs-ithiadiaz-gly-betadhbfu 5698: phhs-25thiaz-gly-busu2be
5699: bhs-nme35pyr-bala-betambiph5699: bhs-nme35pyr-bala-betambiph
5700: bim-24thioph-gly-betapy5700: bim-24thioph-gly-betapy
5701 : ibhs-nme35pyr-gly-betadcphtb 5 5702: bim-25methiaz-gly-psdap5701: ibhs-nme35pyr-gly-betadcphtb 5 5702: bim-25methiaz-gly-psdap
5703: phhs-nme35pyr-bala-betaipr5703: phhs-nme35pyr-bala-betaipr
5704: gua-25thiaz-gly-betainyl5704: gua-25thiaz-gly-betainyl
5705: bhs-25oxaz-bala-betafluo5705: bras-25oxaz-bala-betafluo
5706: gua-25thioph-gly-betahmph5706: gua-25thioph-gly-betahmph
5707 : tolhs-24thioph-gly-betainyl5707: tolhs-24thioph-gly-betainyl
10 5708: bhs-24thioph-bala-betaet10 5708: bhs-24thioph-bala-betet
5709: tolhs-25oxaz-bala-betafu35709: tolhs-25oxaz-bala-betafu3
5710 : 2py-24thiaz-bala-beta34dcph5710: 2py-24thiaz-bala-beta34dcph
5711: gua-42pym-gly-betaph5711: gua-42pym-gly-betaph
5712: tolhs-ithiadiaz-gly-betahni 15 5713: 2py-42nmeim-leu-psdap5712: tolhs-ithiadiaz-gly-betahni 15 5713: 2py-42nmeim-leu-psdap
5714: 2py-24thiaz-hphe-psdap5714: 2py-24thiaz-hphe-psdap
5715: phhs-nme35pyr-gly-zdapee5715: phhs-nme35pyr-gly-zdapee
5716: bhs-26py-ala-betapy5716: bhs-26py-ala-betapy
5717: ibhs-25methiaz-gly-betabph 20 5718: bhs-25methiaz-bala-betaphethioa5717: ibhs-25methiaz-gly-betabph 20 5718: bhs-25methiaz-bala-betaphethioa
5719: tolhs-me25thiaz-ala-zdap5719: tolhs-me25thiaz-ala-zdap
5720: bhs-24thioph-bala-beta3quin5720: bhs-24thioph-bala-beta3quin
5721: dhim-25thioph-ala-betainyl5721: dhim-25thioph-ala-betainyl
5722 : phhs-oxadiaz-gly-betahph5722: phhs-oxadiaz-gly-betahph
5723: tolhs-25oxaz-gly-betatbuph5723: tolhs-25oxaz-gly-betatbuph
25 5724 : bhs-oxadiaz-gly-betaphethio25 5724: bhs-oxadiaz-gly-betaphethio
5725: bim-me24oxaz-ala-betaph5725: bim-me24oxaz-ala-betaph
5726 : tolhs-me25thiaz-leu-beta34meoph5726: tolhs-me25thiaz-leu-beta34meoph
5727: bim-24im-bala-betapy5727: bim-24im-bala-betapy
5728: phhs-ithiadiaz-bala-betahb 30 5729: tolhs-25methiaz-gly-beta35dbph5728: phhs-ithiadiaz-bala-betahb 30 5729: tolhs-25methiaz-gly-beta35dbph
5730 : ibhs-25thiaz-bala-betadcphee5730: ibhs-25thiaz-bala-betadcphee
5731 : ibhs-oxadiaz-bala-beta23meoph5731: ibhs-oxadiaz-bala-beta23meoph
5732: gua-24oxaz-gly-betatrif5732: gua-24oxaz-gly betatrif
5733: 2py-25thioph-ala-zdap 35 5734: bhs-42oxaz-leu-betadcph5733: 2py-25thioph-ala-zdap 35 5734: bhs-42oxaz-leu-betadcph
5735: bhs-triaz-bala-betapy5735: bras-triaz-bala-betapy
5736 : phhs-25methiaz-bala-beta34dcph5736: phhs-25methiaz-bala-beta34dcph
5737 : tolhs-ithiadiaz-gly-betabediox5737: tolhs-ithiadiaz-gly-betabediox
5738 : phhs-oxadiaz-bala-betal3bendi5738: phhs-oxadiaz-bala-betal3bendi
5739: ibhs-25thiaz-bala-betahmo5739: ibhs-25thiaz-bala-betahmo
40 5740 : tolhs-25methiaz-bala-betadhbfu40 5740: tolhs-25methiaz-bala-betadhbfu
5741: 2py-me24oxaz-leu-betapy5741: 2py-me24oxaz-leu-betapy
5742 : phhs-ithiadiaz-bala-betafluo5742: phhs-ithiadiaz-bala-betafluo
5743 : tolhs-24thioph-bala-betathiome5743: tolhs-24thioph-bala-betathiome
5744: bhs-52thiaz-gly-psdap 45 5745: tolhs-oxadiaz-gly-betabediox5744: bhs-52thiaz-gly-psdap 45 5745: tolhs-oxadiaz-gly-betabediox
5746 : bhs-ithiadiaz-ala-betabnaphth5746: bhs-ithiadiaz-ala-betabnaphth
5747: phhs-oxadiaz-bala-betaamibe 5748 : ibhs-oxadiaz-bala-betadcphch5747: phhs-oxadiaz-bala-betaamibe 5748: ibhs-oxadiaz-bala-betadcphch
5749: phhs-24thioph-bala-betafu25749: phhs-24thioph-bala-betafu2
5750 : bhs-ithiadiaz-bala-betaoxope5750: bhs-ithiadiaz-bala-betaoxope
5751: phhs-25oxaz-gly-betaoxaz 5 5752: ibhs-oxadiaz-bala-betaphethio5751: phhs-25oxaz-gly-betaoxaz 5 5752: ibhs-oxadiaz-bala-betaphethio
5753 : bhs-25methiaz-nmgly-beta34meoph5753: bhs-25methiaz-nmgly-beta34meoph
5754 : bhs-nme35pyr-gly-betadcph5754: bhs-nme35pyr-gly-betadcph
5755: 2py-24oxaz-gly-betapy5755: 2py-24oxaz-gly-betapy
5756: tolhs-25thiaz-bala-psdapch5756: tolhs-25thiaz-bala-psdapch
5757: bhs-25thiaz-bala-betaoxaz5757: bhs-25thiaz-bala-betaoxaz
10 5758: bhs-24oxaz-gly-betameph10 5758: bhs-24oxaz-gly-betameph
5759: bhs-24thioph-ala-betathioph5759: bhs-24thioph-ala-betathioph
5760: ibhs-25oxaz-bala-betaipro5760: ibhs-25oxaz-bala-betaipro
5761: phhs-ithiadiaz-bala-betambiph5761: phhs-ithiadiaz-bala-betambiph
5762 : phhs-24thioph-bala-betaibph 15 5763: ibhs-ithiadiaz-bala-betadito5762: phhs-24thioph-bala-betaibph 15 5763: ibhs-ithiadiaz-bala-betadito
5764 : tolhs-ithiadiaz-bala-betadcphee5764: tolhs-ithiadiaz-bala-betadcphee
5765: tolhs-oxadiaz-gly-aspbzla5765: tolhs-oxadiaz-gly-aspbzla
5766: phhs-nme35pyr-gly-betaoxaz5766: phhs-nme35pyr-gly-betaoxaz
5767: bhs-42nmeim-gly-beta34dcph 20 5768: ibhs-oxadiaz-gly-betadito5767: bhs-42nmeim-gly-beta34dcph 20 5768: ibhs-oxadiaz-gly-betadito
5769: bhs-nme35pyr-gly-betahbcph5769: bhs-nme35pyr-gly-betahbcph
5770 : tolhs-24thioph-bala-betamethioph5770: tolhs-24thioph-bala-betamethioph
5771: bhs-25methiaz-gly-beta23meoph5771: bhs-25methiaz-gly-beta23meoph
5772: bhs-25methiaz-ala-betahmph5772: bhs-25methiaz-ala-betahmph
5773 : ibhs-25methiaz-bala-betadcphtb5773: ibhs-25methiaz-bala-betadcphtb
25 5774: tolhs-24thioph-gly-betadbph25 5774: tolhs-24thioph-gly-betadbph
5775 : tolhs-ithiadiaz-bala-betaet5775: tolhs-ithiadiaz-bala-betet
5776 : ibhs-ithiadiaz-gly-beta3quin5776: ibhs-ithiadiaz-gly-beta3quin
5777: 2pmhs-42nmeim-met-betapy5777: 2 pmhs-42nmeim-met-betapy
5778: ibhs-24thioph-gly-betafph 30 5779: ibhs-ithiadiaz-gly-betadbph5778: ibhs-24thioph-gly-betafph 30 5779: ibhs-ithiadiaz-gly-betadbph
5780: phhs-25thiaz-bala-beta34meoph5780: phhs-25thiaz-bala-beta34meoph
5781: phhs-25oxaz-bala-betamesu5781: phhs-25oxaz-bala-betamesu
5782: bim-24thiaz-bala-betampy5782: bim-24thiaz-bala-betampy
5783 : ibhs-25methiaz-bala-beta34meoph 35 5784: phhs-oxadiaz-gly-aspibua5783: ibhs-25methiaz-bala-beta34meoph 35 5784: phhs-oxadiaz-gly-aspibua
5785: 2py-me24oxaz-bala-betaph5785: 2py-me24oxaz-bala-betaph
5786: bhs-24im-leu-betapy5786: bhs-24im-leu-betapy
5787 : ibhs-25thiaz-gly-betampy5787: ibhs-25thiaz-gly-betampy
5788: 2py-me24thiaz-gly-beta34meoph5788: 2py-me24thiaz-gly-beta34meoph
5789: ibhs-25methiaz-bala-zdaptb5789: ibhs-25methiaz-bala-zdaptb
40 5790: gua-42pym-gly-betapym40 5790: gua-42pym-gly-betapym
5791: phhs-nme35pyr-bala-psdapee5791: phhs-nme35pyr-bala-psdapee
5792: phhs-oxadiaz-bala-betahph5792: phhs-oxadiaz-bala-betahph
5793: bhs-35fur-bala-zdap5793: bras-35fur-bala-zdap
5794: tolhs-25thiaz-bala-psdaptb 45 5795: tolhs-25thiaz-gly-betabph5794: tolhs-25thiaz-bala-psdaptb 45 5795: tolhs-25thiaz-gly-betabph
5796 : phhs-24thioph-bala-betaftrif5796: phhs-24thioph-bala-betaftrif
5797: ibhs-oxadiaz-gly-betamethi 5798: phhs-oxadiaz-bala-ibsdap5797: ibhs-oxadiaz-gly-betamethi 5798: phhs-oxadiaz-bala-ibsdap
5799: ibhs-24thioph-bala-aspbzla5799: ibhs-24thioph-bala-aspbzla
5800 : bim-me25thioph-ala-betadcph5800: bim-me25thioph-ala-betadcph
5801: bhs-24pym-ala-betameph5801: bhs-24pym-ala-betameph
5802: phhs-me25oxaz-ala-psdap5802: phhs-me25oxaz-ala-psdap
5803 : tolhs-24thioph-bala-betacthioph5803: tolhs-24thioph-bala-betacthioph
5804: 2py-24thiaz-gly-betadcph5804: 2py-24thiaz-gly-betadcph
5805: phhs-25thiaz-bala-betadtrif5805: phhs-25thiaz-bala-betadtrif
5806: phhs-me25thioph-leu-zdap5806: phhs-me25thioph-leu-zdap
5807: bhs-42nmeim-bala-zdap5807: bras-42nmeim-bala-zdap
10 5808: ibhs-oxadiaz-gly-betadmph10 5808: ibhs-oxadiaz-gly-betadmph
5809: phhs-25oxaz-bala-aspibua5809: phhs-25oxaz-bala-aspibua
5810: bim-thiadiaz-gly-betapy5810: bim-thiadiaz-gly-betapy
5811 : tolhs-25methiaz-gly-betadcphch5811: tolhs-25methiaz-gly-betadcphch
5812 : ibhs-nme35pyr-bala-betahcbph5812: ibhs-nme35pyr-bala-betahcbph
15 5813: bhs-25methiaz-bala-suabu 5814: tolhs-25oxaz-bala-betadbph 5815 : phhs-ithiadiaz-gly-betaoxaz 5816: bhs-nme35pyr-bala-asppha 5817: tolhs-24thioph-gly-betahb15 5813: bhs-25methiaz-bala-suabu 5814: tolhs-25oxaz-bala-betadbph 5815: phhs-ithiadiaz-gly-betaoxaz 5816: bhs-nme35pyr-bala-asppha 5817: tolhs-24thioph-gly-betahb
20 5818: bim-me25thioph-ala-psdap 5819: gua-24oxaz-gly-zdap 5820 : phhs-25thiaz-gly-betabdimo 5821: phhs-25thiaz-gly-aspaba 5822: bhs-53pyrazo-bala-psdap 5823: 2py-42nmeim-leu-zdap20 5818: bim-me25thioph-ala-psdap 5819: gua-24oxaz-gly-zdap 5820: phhs-25thiaz-gly-betabdimo 5821: phhs-25thiaz-gly-aspaba 5822: bhs-53pyrazo-bala-psdap 5823: 2py- 42nmeim-leu-zdap
25 5824 : phhs-oxadiaz-gly-betadcphee 5825: imhs-25thiaz-gly-zdap 5826: phhs-25thiaz-bala-aspaba 5827: phhs-25methiaz-gly-betadhbfu 5828: bhs-24thiaz-bala-beta34meoph25 5824: phhs-oxadiaz-gly-betadcphee 5825: imhs-25thiaz-gly-zdap 5826: phhs-25thiaz-bala-aspaba 5827: phhs-25methiaz-gly-betadhbfu 5828: bhs-24thiaz-bala-beta34meoph
30 5829: bhs-24thiaz-gly-betahmph 5830 : 2py-me25oxaz-bala-betaph 5831: hyd-42nmeim-bala-betadcph 5832: bhs-25thiaz-bala-beta3quin 5833 : ibhs-ithiadiaz-bala-betabph30 5829: bhs-24thiaz-gly-betahmph 5830: 2py-me25oxaz-bala-betaph 5831: hyd-42nmeim-bala-betadcph 5832: bhs-25thiaz-bala-beta3quin 5833: ibhs-ithiadiaz-bala-betabph
35 5834: ibhs-24thiaz-gly-betapbiph 5835 : 2py-25methiaz-bala-betadcph 5836: 2py-25oxaz-leu-psdap 5837: tolhs-oxadiaz-gly-psdapch 5838: bhs-24thioph-ala-zdap 5839: bhs-24thioph-bala-betapych35 5834: ibhs-24thiaz-gly-betapbiph 5835: 2py-25methiaz-bala-betadcph 5836: 2py-25oxaz-leu-psdap 5837: tolhs-oxadiaz-gly-psdapch 5838: bhs-24thioph-ala-zdap 5839: bhs- 24thioph-bala-betapych
40 5840 : phhs-25thiaz-bala-betadcph 5841: bgua-42pym-gly-betapy 5842: bhs-25methiaz-nmgly-betacph 5843: impy-25oxaz-bala-betafbph 5844 : phhs-24thiaz-gly-betadcphch40 5840: phhs-25thiaz-bala-betadcph 5841: bgua-42pym-gly-betapy 5842: bhs-25methiaz-nmgly-betacph 5843: impy-25oxaz-bala-betafbph 5844: phhs-24thiaz-gly-betadcphch
45 5845: phhs-25methiaz-bala-betaimid 5846 : ibhs-25methiaz-bala-betahmofu 5847: ibhs-24thiaz-bala-betafbph 5848: ibhs-24thiaz-gly-busu2be 5849: 2py-24thioph-hphe-psdap 5850 : 2py-me24thiaz-leu-beta34meoph 5851: phhs-24thiaz-gly-betaet 5852: phhs-25thiaz-gly-betameph 5853 : ibhs-25methiaz-bala-betathiome 5854: tolhs-oxadiaz-bala-betacph 5855: ibhs-nme35pyr-gly-psdaptb 5856: bim-oxadiaz-bala-aspaba 5857: bim-24oxaz-gly-betainyl45 5845: phhs-25methiaz-bala-betaimid 5846: ibhs-25methiaz-bala-betahmofu 5847: ibhs-24thiaz-bala-betafbph 5848: ibhs-24thiaz-gly-busu2be 5849: 2py-24thioph-hphe-psdap 5850: 2py-me24thiaz-leu-beta34meoph 5851: phhs-24thiaz-gly-betet 5852: phhs-25thiaz-gly-betameph 5853: ibhs-25methiaz -bala-betathiome 5854: tolhs-oxadiaz-bala-betacph 5855: ibhs-nme35pyr-gly-psdaptb 5856: bim-oxadiaz-bala-aspaba 5857: bim-24oxaz-gly-betainyl
10 5858: bhs-nme35pyr-gly-betaimid 5859: ibhs-25thiaz-bala-betahph 5860: 2py-25thiaz-gly-betameph 5861: phhs-24thioph-gly-busu2be 5862: tolhs-25oxaz-gly-betaol10 5858: bhs-nme35pyr-gly-betaimid 5859: ibhs-25thiaz-bala-betahph 5860: 2py-25thiaz-gly-betameph 5861: phhs-24thioph-gly-busu2be 5862: tolhs-25oxaz-gly-betaol
15 5863: bhs-24thioph-ala-betafphe 5864: bhs-25thiaz-nmgly-betadmoph 5865: ibhs-oxadiaz-bala-aspbzla 5866 : bhs-ithiadiaz-bala-betacbph 5867: bim-35fur-ala-psdap15 5863: bhs-24thioph-ala-betafphe 5864: bhs-25thiaz-nmgly-betadmoph 5865: ibhs-oxadiaz-bala-aspbzla 5866: bhs-ithiadiaz-bala-betacbph 5867: bim-35fur-ala-psdap
20 5868 : tolhs-25thiaz-gly-betathiome 5869: tolhs-nme35pyr-gly-betahmofu 5870 : ibhs-25methiaz-gly-betaibph 5871: tolhs-25thiaz-bala-betapytb 5872 : impy-25oxaz-gly-betaphethio 5873 : gua-24oxaz-gly-betabthioph20 5868: tolhs-25thiaz-gly-betathiome 5869: tolhs-nme35pyr-gly-betahmofu 5870: ibhs-25methiaz-gly-betaibph 5871: tolhs-25thiaz-bala-betapytb 5872: impy-25oxaz-gly-betaphethio 5873: gua- 24oxaz-gly-beta thioph
25 5874: gua-24thiaz-gly-betahcbph 5875: tolhs-nme35pyr-gly-betapym 5876: bim-me24thiaz-leu-betaph 5877: pahs-24thioph-bala-betameph 5878: bim-25thiaz-gly-betahmph25 5874: gua-24thiaz-gly-betahcbph 5875: tolhs-nme35pyr-gly-betapym 5876: bim-me24thiaz-leu-betaph 5877: pahs-24thioph-bala-betameph 5878: bim-25thiaz-gly-betahmph
30 5879: bhs-25thiaz-gly-betabediox 5880: bhs-24thiaz-gly-betathiobe 5881: gua-42pym-nmgly-betapy 5882: gua-24thiaz-gly-betaipr 5883: tolhs-25thiaz-bala-psdap30 5879: bhs-25thiaz-gly-betabediox 5880: bhs-24thiaz-gly-betathiobe 5881: gua-42pym-nmgly-betapy 5882: gua-24thiaz-gly-betaipr 5883: tolhs-25thiaz-bala-psdap
35 5884: gua-24thiaz-gly-busu2be 5885: bhs-24thiaz-ala-betaoxaz 5886: tolhs-oxadiaz-bala-betabpy 5887: bhs-24thiaz-gly-betapbiph 5888 : bhs-me24oxaz-gly-beta34meoph 5889: bhs-24 hioph-bala-betaoxaz35 5884: gua-24thiaz-gly-busu2be 5885: bhs-24thiaz-ala-betaoxaz 5886: tolhs-oxadiaz-bala-betabpy 5887: bhs-24thiaz-gly-betapbiph 5888: bhs-me24oxaz-gly-beta34meoph 5889: bhs- 24 hioph-bala-betaoxaz
40 5890: tolhs-ithiadiaz-gly-betahmph 5891 : phhs-25methiaz-bala-busu2be 5892: bhs-24im-leu-zdap 5893 : bhs-24thioph-bala-betabpy 5894: bhs-25methiaz-bala-betabpy40 5890: tolhs-ithiadiaz-gly-betahmph 5891: phhs-25methiaz-bala-busu2be 5892: bhs-24im-leu-zdap 5893: bhs-24thioph-bala-betabpy 5894: bhs-25methiaz-bala-betabpy
45 5895: ibhs-25oxaz-bala-betadcphtb 5896: bhs-25methiaz-gly-ibsdap 5897 : phhs-24thiaz-bala-betathioph 5898: phhs-25methiaz-bala-zdap 5899: ibhs-25oxaz-gly-betaamibe 5900: imhs-24thioph-gly-zdap 5901: phhs-oxadiaz-gly-betafluo 5902: 2py-26py-ala-betadcph 5903: 2py-me25thioph-leu-betaph 5904 : tolhs-25methiaz-gly-betaoxope 5905: phhs-ithiadiaz-bala-betaol 5906: tolhs-24thiaz-gly-betadtrif 5907: bhs-25methiaz-gly-psdapee45 5895: ibhs-25oxaz-bala-betadcphtb 5896: bhs-25methiaz-gly-ibsdap 5897: phhs-24thiaz-bala-betathioph 5898: phhs-25methiaz-bala-zdap 5899: ibhs-25oxaz-gly-betaamibe 5900: imhs-24thioph-gly-zdap 5901: phhs-oxadiaz-gly-betafluo 5902: 2py-26py-ala-betadcph 5903: 2py-me25 -leu-betaph 5904: tolhs-25methiaz-gly-betaoxope 5905: phhs-ithiadiaz-bala-betaol 5906: tolhs-24thiaz-gly-betadtrif 5907: bhs-25methiaz-gly-psdapee
10 5908 : bhs-ithiadiaz-gly-beta23meoph 5909: bhs-me24thiaz-gly-zdap 5910: 2pmhs-25methiaz-gly-betafph 5911: bhs-25oxaz-bala-betadtrif 5912: bhs-25methiaz-bala-betatos10 5908: bhs-ithiadiaz-gly-beta23meoph 5909: bhs-me24thiaz-gly-zdap 5910: 2 pmhs-25methiaz- gly-betafph 5911: bhs-25oxaz-bala-betadtrif 5912: bhs-25methiaz-bala-betatos
15 5913: bim-24thioph-bala-psdap15 5913: bim-24thioph-bala-psdap
5914 : tolhs-nme35pyr-bala-betafbph 5915: tolhs-24thiaz-bala-aspaba 5916: 2py-triaz-gly-betadcph 5917: ibhs-24thiaz-gly-betahph5914: tolhs-nme35pyr-bala-betafbph 5915: tolhs-24thiaz-bala-aspaba 5916: 2py-triaz-gly-betadcph 5917: ibhs-24thiaz-gly-betahph
20 5918: tolhs-nme35pyr-gly-beta4bph 5919 : tolhs-ithiadiaz-bala-beta4bph 5920: phhs-25oxaz-gly-betadcph 5921: phhs-25methiaz-bala-betadmoph 5922: phhs-oxadiaz-gly-csdap 5923 : tolhs-oxadiaz-bala-betadmph20 5918: tolhs-nme35pyr-gly-beta4bph 5919: tolhs-ithiadiaz-bala-beta4bph 5920: phhs-25oxaz-gly-betadcph 5921: phhs-25methiaz-bala-betadmoph 5922: phhs-oxadiaz-gly-cshs- 5923: t oxadiaz-bala-betadmph
25 5924: impy-42nmeim-bala-betahbcph 5925: tolhs-24thioph-gly-csdap 5926: ibhs-24thioph-bala-betahmph 5927: bhs-ithiadiaz-bala-betapyr 5928: tolhs-25thiaz-gly-betathiobe25 5924: impy-42nmeim-bala-betahbcph 5925: tolhs-24thioph-gly-csdap 5926: ibhs-24thioph-bala-betahmph 5927: bhs-ithiadiaz-bala-betapyr 5928: tolhs-25thiaz-gly-betathiobe
30 5929: bhs-nme35pyr-bala-betabpy 5930: phhs-oxadiaz-gly-betadmph 5931: tolhs-24thiaz-bala-betadcphch 5932: dhim-25thioph-ala-betameph 5933 : bhs-24thioph-bala-betaomebendi30 5929: bhs-nme35pyr-bala-betabpy 5930: phhs-oxadiaz-gly-betadmph 5931: tolhs-24thiaz-bala-betadcphch 5932: dhim-25thioph-ala-betameph 5933: bhs-24thioph-bala-betaomebendi
35 5934 : phhs-25oxaz-bala-betadmph 5935: bim-me24oxaz-leu-betapy 5936: bhs-oxadiaz-gly-betainyl 5937 : tolhs-oxadiaz-gly-betaanaphth 5938 : tolhs-24thioph-bala-betabph 5939: phhs-25thiaz-bala-betambiph35 5934: phhs-25oxaz-bala-betadmph 5935: bim-me24oxaz-leu-betapy 5936: bhs-oxadiaz-gly-betainyl 5937: tolhs-oxadiaz-gly-betaanaphth 5938: tolhs-24thioph-bala-betabph 5939: phhs- 25thiaz-bala-betambiph
40 5940: bhs-me25oxaz-bala-zdap 5941: 2pmhs-25oxaz-bala-betaet 5942: phhs-24thioph-gly-betahph 5943 : bhs-oxadiaz-gly-betadtrif 5944 : 2py-oxadiaz-leu-betapy40 5940: bhs-me25oxaz-bala-zdap 5941: 2 pmhs-25oxaz-bala-betaet 5942: phhs-24thioph-gly-betahph 5943: bhs-oxadiaz-gly-betadtrif 5944: 2py-oxadiaz-leu-betapy
45 5945: bhs-nme35pyr-bala-betaheph 5946: bim-25fur-gly-betapy 5947 : bhs-25methiaz-gly-betaoxope 5948: tolhs-25oxaz-gly-betatrif45 5945: bhs-nme35pyr-bala-betaheph 5946: bim-25fur-gly-betapy 5947: bhs-25methiaz-gly-betaoxope 5948: tolhs-25oxaz-gly-betatrif
5949: dhthi-25oxaz-gly-zdap5949: dhthi-25oxaz-gly-zdap
5950 : bhs-oxadiaz-nmgly-beta23meoph5950: bhs-oxadiaz-nmgly-beta23meoph
5951: tolhs-25oxaz-gly-betaibph 5 5952: phhs-24thiaz-bala-betaanaphth5951: tolhs-25oxaz-gly-betaibph 5 5952: phhs-24thiaz-bala-betaanaphth
5953: bim-24thiaz-bala-betacph5953: bim-24thiaz-bala-betacph
5954: 2py-42nmeim-bala-betadcph5954: 2py-42nmeim-bala-betadcph
5955: ibhs-25thiaz-gly-psdapee5955: ibhs-25thiaz-gly-psdapee
5956 : bhs-ithiadiaz-nmgly-beta3quin5956: bhs-ithiadiaz-nmgly-beta3quin
5957: tolhs-24thioph-gly-betaheph5957: tolhs-24thioph-gly-betaheph
1010
5958: bhs-ithiadiaz-ala-beta34meoph5958: bhs-ithiadiaz-ala-beta34meoph
5959: phhs-25oxaz-bala-csdap5959: phhs-25oxaz-bala-csdap
5960 : tolhs-ithiadiaz-gly-betabenfu5960: tolhs-ithiadiaz-gly-betabenfu
5961: ibhs-ithiadiaz-gly-betafu35961: ibhs-ithiadiaz-gly-betafu3
5962: bhs-26py-ala-betainyl 15 5963: bim-me25thioph-ala-zdap5962: bhs-26py-ala-betainyl 15 5963: bim-me25thioph-ala-zdap
5964: phhs-nme35pyr-bala-aspibua5964: phhs-nme35pyr-bala-aspibua
5965: phhs-ithiadiaz-bala-zdap5965: phhs-ithiadiaz-bala-zdap
5966 : ibhs-oxadiaz-bala-betadcphee5966: ibhs-oxadiaz-bala-betadcphee
5967 : tolhs-oxadiaz-gly-betathioph 20 5968: impy-25methiaz-bala-busu2be5967: tolhs-oxadiaz-gly-betathioph 20 5968: impy-25methiaz-bala-busu2be
5969: bhs-ithiadiaz-bala-suabu5969: bhs-ithiadiaz-bala-suabu
5970 : bhs-nme35pyr-nmgly-betacthioph5970: bhs-nme35pyr-nmgly-betacthioph
5971: bhs-35fur-bala-psdap5971: bras-35fur-bala-psdap
5972: bhs-24thiaz-bala-betaftrif5972: bras-24thiaz-bala-betaftrif
5973: bhs-25oxaz-gly-betafbph5973: bhs-25oxaz-gly-betafbph
25 5974: tolhs-25thiaz-gly-betaibph25 5974: tolhs-25thiaz-gly-betaibph
5975: 2py-me24thiaz-gly-betadcph5975: 2py-me24thiaz-gly-betadcph
5976: 2py-me24oxaz-bala-psdap5976: 2py-me24oxaz-bala-psdap
5977: bim-ithiadiaz-ala-betadcph5977: bim-ithiadiaz-ala-betadcph
5978: 2py-25thiaz-gly-betaol 30 5979: phhs-25oxaz-bala-zdapee5978: 2py-25thiaz-gly-betaol 30 5979: phhs-25oxaz-bala-zdapee
5980: tolhs-25thiaz-bala-beta23meoph5980: tolhs-25thiaz-bala-beta23meoph
5981: bhs-25thiaz-gly-betahbcph5981: bhs-25thiaz-gly-betahbcph
5982: ibhs-oxadiaz-gly-betahmofu5982: ibhs-oxadiaz-gly-betahmofu
5983 : ibhs-ithiadiaz-gly-betahbcph 35 5984: 2py-25thiaz-bala-betahni5983: ibhs-ithiadiaz-gly-betahbcph 35 5984: 2py-25thiaz-bala-betahni
5985: tolhs-24thiaz-bala-betaipr5985: tolhs-24thiaz-bala-betaipr
5986: 2py-25thioph-ala-betapy5986: 2py-25thioph-ala-betapy
5987 : ibhs-oxadiaz-gly-betabthioph5987: ibhs-oxadiaz-gly-betabthioph
5988: ibhs-25methiaz-gly-betapym5988: ibhs-25methiaz-gly-betapym
5989: 2py-24thiaz-bala-betadcph5989: 2py-24thiaz-bala-betadcph
40 5990: phhs-me25thioph-leu-betadcph40 5990: phhs-me25thioph-leu-betadcph
5991: ibhs-24thioph-gly-betainyl5991: ibhs-24thioph-gly-betainyl
5992 : phhs-24thiaz-bala-betatbuph5992: phhs-24thiaz-bala-betatbuph
5993: tolhs-oxadiaz-bala-psdaptb5993: tolhs-oxadiaz-bala-psdaptb
5994: dhim-24oxaz-ala-betapy 45 5995: ibhs-25methiaz-bala-betafluo5994: dhim-24oxaz-ala-betapy 45 5995: ibhs-25methiaz-bala-betafluo
5996: gua-26py-gly-betahph5996: gua-26py-gly-betahph
5997: phhs-25thiaz-bala-psdapee 5998: phhs-24thiaz-gly-betaol 5999: bhs-25methiaz-bala-betaol 6000: 2py-nme35pyr-gly-aspibua 6001: ibhs-25oxaz-gly-beta35dbph 6002: tolhs-nme35pyr-gly-betahb 6003: ibhs-nme35pyr-g1y-betaheph 6004: bhs-25oxaz-nmgly-betamesu 6005: 2py-24oxaz-ala-betadcph 6006: ibhs-ithiadiaz-gly-betaamibe 6007 : tolhs-24thioph-gly-betadcphee5997: phhs-25thiaz-bala-psdapee 5998: phhs-24thiaz-gly-betaol 5999: bhs-25methiaz-bala-betaol 6000: 2py-nme35pyr-gly-aspibua 6001: ibhs-25oxaz-gly-beta35dbph 6002: tolhs-nme35pyr-gly-betahb 6003: ibhs-nme35yr -g1y-betaheph 6004: bhs-25oxaz-nmgly-betamesu 6005: 2py-24oxaz-ala-betadcph 6006: ibhs-ithiadiaz-gly-betaamibe 6007: tolhs-24thioph-gly-betadcphee
10 6008: tolhs-25thiaz-bala-asppha 6009: bhs-24thioph-bala-betadhbfu 6010 : ibhs-ithiadiaz-bala-betadbph 6011: phhs-oxadiaz-gly-betathio3 6012: bhs-nme35pyr-nmgly-ibsdap10 6008: tolhs-25thiaz-bala-asppha 6009: bhs-24thioph-bala-betadhbfu 6010: ibhs-ithiadiaz-bala-betadbph 6011: phhs-oxadiaz-gly-betathio3 6012: bhs-nme35pyr-nmgly-ibsdap
15 6013: ibhs-24thiaz-gly-betamethioph 6014 : ibhs-oxadiaz-bala-betathio3 6015: 2py-25oxaz-nmgly-betadcph 6016: 2py-42nmeim-gly-betahcbph 6017 : tolhs-24thioph-gly-betahdbph15 6013: ibhs-24thiaz-gly-betamethioph 6014: ibhs-oxadiaz-bala-betathio3 6015: 2py-25oxaz-nmgly-betadcph 6016: 2py-42nmeim-gly-betahcbph 6017: tolhs-24thioph-gly-betahdbph
20 6018: ibhs-nme35pyr-gly-betahdbph 6019 : ibhs-24thiaz-gly-betabthioph 6020: bhs-25oxaz-bala-betapym 6021 : ibhs-25methiaz-bala-betadito 6022: bhs-25thiaz-gly-betapbiph 6023: bhs-ithiadiaz-gly-betaibph20 6018: ibhs-nme35pyr-gly-betahdbph 6019: ibhs-24thiaz-gly-betabthioph 6020: bhs-25oxaz-bala-betapym 6021: ibhs-25methiaz-bala-betadito 6022: bhs-25thiaz-gly-betapbiph 6023: bhs- ithiadiaz-gly-betaibph
25 6024: ibhs-24thiaz-gly-betahni 6025: phhs-25oxaz-bala-betameph 6026: 2py-ithiadiaz-gly-aspbzla 6027 : bhs-25methiaz-gly-betathiome 6028: phhs-ithiadiaz-gly-betahdcph25 6024: ibhs-24thiaz-gly-betahni 6025: phhs-25oxaz-bala-betameph 6026: 2py-ithiadiaz-gly-aspbzla 6027: bhs-25methiaz-gly-betathiome 6028: phhs-ithiadiaz-gly-betahdcph
30 6029: tolhs-nme35pyr-bala-betaheph 6030: tolhs-25thiaz-bala-betabph 6031: phhs-nme35pyr-bala-betatos 6032 : phhs-me25thiaz-gly-beta34meoph 6033 : tolhs-25methiaz-gly-betatrif30 6029: tolhs-nme35pyr-bala-betaheph 6030: tolhs-25thiaz-bala-betabph 6031: phhs-nme35pyr-bala-betatos 6032: phhs-me25thiaz-gly-beta34meoph 6033: tolhs-25methiaz-gly-betatrif
35 6034: tolhs-nme35pyr-gly-betacbph 6035: bim-25oxaz-gly-aspaba 6036: bhs-nme35pyr-bala-betabnaphth 6037 : ibhs-24thioph-bala-betainyl 6038 : phhs-ithiadiaz-gly-betaibph 6039 : tolhs-nme35pyr-gly-betaftrif35 6034: tolhs-nme35pyr-gly-betacbph 6035: bim-25oxaz-gly-aspaba 6036: bhs-nme35pyr-bala-betabnaphth 6037: ibhs-24thioph-bala-betainyl 6038: phhs-ithiadiaz-gly-betaibph 6039: tolh nme35pyr-gly-betaftrif
40 6040: ur-25thiaz-gly-betainyl 6041: bim-oxadiaz-leu-betadcph 6042 : phhs-oxadiaz-gly-betaipr 6043 : tolhs-25thiaz-bala-betafphe 6044: cima-24thiaz-gly-betainyl40 6040: ur-25thiaz-gly-betainyl 6041: bim-oxadiaz-leu-betadcph 6042: phhs-oxadiaz-gly-betaipr 6043: tolhs-25thiaz-bala-betafphe 6044: cima-24thiaz-gly-betainyl
45 6045: ibhs-25oxaz-gly-csdap 6046: bhs-25oxaz-bala-betathio3 6047: phhs-me25thioph-gly-betapy 6048: tolhs-me24thiaz-gly-beta34meoph45 6045: ibhs-25oxaz-gly-csdap 6046: bhs-25oxaz-bala-betathio3 6047: phhs-me25thioph-gly-betapy 6048: tolhs-me24thiaz-gly-beta34meoph
6049: bim-25oxaz-phe-betapy6049: bim-25oxaz-phe-betapy
6050: tolhs-25thiaz-bala-betaphethio6050: tolhs-25thiaz-bala-betaphethio
6051: dhim-24thiaz-ala-betainyl 5 6052: tolhs-oxadiaz-bala-betaet6051: dhim-24thiaz-ala-betainyl 5 6052: tolhs-oxadiaz-bala-betaet
6053: tolhs-me24thiaz-ala-zdap6053: tolhs-me24thiaz-ala-zdap
6054: tolhs-25oxaz-bala-betatos6054: tolhs-25oxaz-bala-betatos
6055: ibhs-24thiaz-gly-betatrif6055: ibhs-24thiaz-gly-betatrif
6056: tolhs-oxadiaz-gly-betahbcph6056: tolhs-oxadiaz-gly-betahbcph
6057: ibhs-25oxaz-gly-betaol6057: ibhs-25oxaz-gly-betaol
10 6058: 2py-triaz-leu-psdap10 6058: 2py-triaz-leu-psdap
6059: phhs-nme35pyr-gly-betahmofu6059: phhs-nme35pyr-gly-betahmofu
6060 : bhs-ithiadiaz-bala-betafphe6060: bras-ithiadiaz-bala-betafphe
6061: phhs-nme35pyr-gly-busu2be6061: phhs-nme35pyr-gly-busu2be
6062: tolhs-me25thioph-leu-psdap 15 6063: thazep-42pym-gly-betapy6062: tolhs-me25thioph-leu-psdap 15 6063: thazep-42pym-gly-betapy
6064 : ibhs-oxadiaz-bala-betal3bendi6064: ibhs-oxadiaz-bala-betal3bendi
6065: tolhs-25thiaz-gly-betafu36065: tolhs-25thiaz-gly-betafu3
6066: ibhs-oxadiaz-gly-betacbph6066: ibhs-oxadiaz-gly-betacbph
6067: gua-25thiaz-gly-betabpy 20 6068: phhs-nme35pyr-bala-csdap6067: gua-25thiaz-gly-betabpy 20 6068: phhs-nme35pyr-bala-csdap
6069: bim-53pyrazo-gly-psdap6069: bim-53pyrazo-gly-psdap
6070 : ibhs-ithiadiaz-bala-betaimid6070: ibhs-ithiadiaz-bala-betaimid
6071: bhs-52thiaz-ala-zdap6071: bhs-52thiaz-ala-zdap
6072: ibhs-24thiaz-bala-betaheph6072: ibhs-24thiaz-bala-betaheph
6073: tolhs-25oxaz-gly-betatos6073: tolhs-25oxaz-gly-betatos
25 6074: 2py-24oxaz-bala-betadcph25 6074: 2py-24oxaz-bala-betadcph
6075: bhs-35thioph-leu-zdap6075: bhs-35thioph-leu-zdap
6076: bhs-ithiadiaz-bala-zdapch6076: bhs-ithiadiaz-bala-zdapch
6077 : bhs-24thioph-nmgly-betaanaphth6077: bhs-24thioph-nmgly-betaanaphth
6078: tolhs-25methiaz-gly-psdap 30 6079: bhs-me24oxaz-ala-betapy6078: tolhs-25methiaz-gly-psdap 30 6079: bhs-me24oxaz-ala-betapy
6080 : ibhs-25methiaz-gly-betadhbfu6080: ibhs-25methiaz-gly-betadhbfu
6081: bhs-25thiaz-bala-ibsdap6081: bhs-25thiaz-bala-ibsdap
6082: tolhs-nme35pyr-gly-betahdbph6082: tolhs-nme35pyr-gly-betahdbph
6083: 2py-42nmeim-bala-betaibph 35 6084: phhs-24thiaz-gly-betadbph6083: 2py-42nmeim-bala-betaibph 35 6084: phhs-24thiaz-gly-betadbph
6085: phhs-25oxaz-bala-betafphe6085: phhs-25oxaz-bala-betafphe
6086: 2py-26py-gly-zdap6086: 2py-26py-gly-zdap
6087 : tolhs-oxadiaz-gly-betabthioph6087: tolhs-oxadiaz-gly-betabthioph
6088: tolhs-25oxaz-bala-betadtrif6088: tolhs-25oxaz-bala-betadtrif
6089: bim-me25oxaz-leu-betaph6089: bim-me25oxaz-leu-betaph
40 6090 : ibhs-ithiadiaz-bala-beta34meoph40 6090: ibhs-ithiadiaz-bala-beta34meoph
6091: phhs-nme35pyr-gly-zdaptb6091: phhs-nme35pyr-gly-zdaptb
6092: ibhs-24thiaz-bala-aspibua6092: ibhs-24thiaz-bala-aspibua
6093: tolhs-24thioph-gly-betabpy6093: tolhs-24thioph-gly-betabpy
6094: bhs-ithiadiaz-gly-betadmoph 45 6095: gua-24 hiaz-gly-betaphethio6094: bhs-ithiadiaz-gly-betadmoph 45 6095: gua-24 hiaz-gly-betaphethio
6096: phhs-oxadiaz-bala-betadtrif6096: phhs-oxadiaz-bala-betadtrif
6097: ibhs-24thioph-bala-asppha 6098 : phhs-nme35pyr-gly-betacthioph6097: ibhs-24thioph-bala-asppha 6098: phhs-nme35pyr-gly-betacthioph
6099 : tolhs-25methiaz-bala-betaanaphth6099: tolhs-25methiaz-bala-betaanaphth
6100 : bhs-ithiadiaz-gly-betadcphch6100: bhs-ithiadiaz-gly-betadcphch
6101: bhs-25methiaz-bala-betahni6101: bras-25methiaz-bala-betahni
6102: bhs-24thiaz-gly-psdapch6102: bhs-24thiaz-gly-psdapch
6103: bim-42nmeim-leu-betadcph6103: bim-42nmeim-leu-betadcph
6104 : tolhs-24thioph-bala-beta34meoph6104: tolhs-24thioph-bala-beta34meoph
6105: tolhs-24thiaz-bala-betafph6105: tolhs-24thiaz-bala-betafph
6106: tolhs-oxadiaz-gly-betaph6106: tolhs-oxadiaz-gly-betaph
6107: phhs-ithiadiaz-gly-aspaba6107: phhs-ithiadiaz-gly-aspaba
10 6108: phhs-25oxaz-bala-ibsdap10 6108: phhs-25oxaz-bala-ibsdap
6109: ibhs-25thiaz-gly-betabpy6109: ibhs-25thiaz-gly-betabpy
6110 : bhs-25methiaz-bala-betabnaphth6110: bras-25methiaz-bala-betabnaphth
6111: tolhs-25oxaz-bala-betambiph6111: tolhs-25oxaz-bala-betambiph
6112 : tolhs-me25thioph-gly-beta34meoph6112: tolhs-me25thioph-gly-beta34meoph
15 6113: tolhs-25oxaz-bala-betathiome 6114: dhim-25thioph-gly-betainyl 6115: ibhs-25oxaz-bala-aspibua 6116: phhs-oxadiaz-gly-suabu 6117 : ibhs-nme35pyr-bala-beta35dbph15 6113: tolhs-25oxaz-bala-betathiome 6114: dhim-25thioph-gly-betainyl 6115: ibhs-25oxaz-bala-aspibua 6116: phhs-oxadiaz-gly-suabu 6117: ibhs-nme35pyr-bala-beta35dbph
20 6118: 2py-25methiaz-leu-psdap 6119: bim-thiadiaz-gly-psdap 6120 : ibhs-ithiadiaz-gly-betadcphch 6121 : tolhs-oxadiaz-bala-betaibph 6122 : bhs-ithiadiaz-bala-betafph 6123: ibhs-oxadiaz-bala-betahdbph20 6118: 2py-25methiaz-leu-psdap 6119: bim-thiadiaz-gly-psdap 6120: ibhs-ithiadiaz-gly-betadcphch 6121: tolhs-oxadiaz-bala-betaibph 6122: bhs-ithiadiaz-bala-betafph 6123: oxadiaz-bala-betahdbph
25 6124: bhs-25thiaz-bala-betafph 6125: phhs-nme35pyr-gly-betapym 6126: ibhs-25oxaz-bala-betadcph 6127 : phhs-25oxaz-bala-betahdbph 6128: tolhs-oxadiaz-bala-betadmoph25 6124: bhs-25thiaz-bala-betafph 6125: phhs-nme35pyr-gly-betapym 6126: ibhs-25oxaz-bala-betadcph 6127: phhs-25oxaz-bala-betahdbph 6128: tolhs-oxadiaz-bala-betadmoph
30 6129: tolhs-24thioph-gly-betahdcph 6130: bhs-25methiaz-bala-betaph 6131: bhs-25thiaz-gly-betapyee 6132 : tolhs-25methiaz-bala-betaimid 6133 : gua-42pym-gly-betathio330 6129: tolhs-24thioph-gly-betahdcph 6130: bhs-25methiaz-bala-betaph 6131: bhs-25thiaz-gly-betapyee 6132: tolhs-25methiaz-bala-betaimid 6133: gua-42pym-gly-betathio3
35 6134 : bhs-25methiaz-nmgly-beta23meoph 6135: sabhs-42nmeim-gly-betapy 6136 : bhs-24thiaz-bala-betathioph 6137 : impy-25methiaz-bala-betaphethioa 6138: bhs-nme35pyr-gly-suabu 6139: tolhs-ithiadiaz-gly-betapy35 6134: bhs-25methiaz-nmgly-beta23meoph 6135: sabhs-42nmeim-gly-betapy 6136: bhs-24thiaz-bala-betathioph 6137: impy-25methiaz-bala-betaphethioa 6138: bhs-nme35pyr-gly-suabolh613 ithiadiaz-gly-betapy
40 6140 : phhs-oxadiaz-gly-zdaptb 6141 : phhs-ithiadiaz-gly-betahcbph 6142: tolhs-me24oxaz-ala-psdap 6143 : bhs-oxadiaz-gly-betahmph 6144 : ibhs-ithiadiaz-bala-betamesu40 6140: phhs-oxadiaz-gly-zdaptb 6141: phhs-ithiadiaz-gly-betahcbph 6142: tolhs-me24oxaz-ala-psdap 6143: bhs-oxadiaz-gly-betahmph 6144: ibhs-ithiadiaz-bala-betamesu
45 6145: bim-52thiaz-ala-zdap45 6145: bim-52thiaz-ala-zdap
6146: bhs-24thioph-ala-beta34dcph 6147: ibhs-24thiaz-bala-ibsdap 6148 : tolhs-ithiadiaz-bala-betabnaphth 6149 : ibhs-oxadiaz-gly-betadcphtb 6150 : tolhs-oxadiaz-bala-betafphe 6151: tolhs-nme35pyr-gly-betapytb 6152: bhs-53pyrazo-ala-betadcph 6153: 2py-26py-nmala-zdap 6154: bhs-25oxaz-gly-betaheph 6155: bhs-25thiaz-gly-betapym 6156: bhs-24thiaz-leu-betapy 6157: phhs-oxadiaz-bala-betadhbfu6146: bhs-24thioph-ala-beta34dcph 6147: ibhs-24thiaz-bala-ibsdap 6148: tolhs-ithiadiaz-bala-betabnaphth 6149: ibhs-oxadiaz-gly-betadcphtb 6150: tolhs-oxadiaz-bala-betafphe 6151: tolhs-nme35pyr-gly-betapytb 6152: bhs-53 -ypyrazop al -nmala-zdap 6154: bhs-25oxaz-gly-betaheph 6155: bhs-25thiaz-gly-betapym 6156: bhs-24thiaz-leu-betapy 6157: phhs-oxadiaz-bala-betadhbfu
10 6158: phhs-oxadiaz-bala-asppha 6159: bhs-25thioph-gly-betainyl 6160: tolhs-oxadiaz-gly-zdap 6161: impy-25thiaz-ala-betapy 6162 : tolhs-25methiaz-gly-busu2be10 6158: phhs-oxadiaz-bala-asppha 6159: bhs-25thioph-gly-betainyl 6160: tolhs-oxadiaz-gly-zdap 6161: impy-25thiaz-ala-betapy 6162: tolhs-25methiaz-gly-busu2be
15 6163: 2py-35thioph-leu-psdap15 6163: 2py-35thioph-leu-psdap
6164 : phhs-25methiaz-bala-betabpy 6165: 2py-26py-gly-betabnaphth 6166: bhs-25methiaz-bala-betahbcph 6167: ibhs-24thioph-gly-betaipr6164: phhs-25methiaz-bala-betabpy 6165: 2py-26py-gly-betabnaphth 6166: bhs-25methiaz-bala-betahbcph 6167: ibhs-24thioph-gly-betaipr
20 6168: bhs-oxadiaz-bala-betaimid20 6168: bras-oxadiaz-bala-betaimide
6169: impy-25oxaz-bala-betabdimo6169: impy-25oxaz-bala-betabdimo
6170: gua-24thiaz-gly-betapbiph6170: gua-24thiaz-gly-betapbiph
6171: tolhs-24thioph-gly-betal3bendi6171: tolhs-24thioph-gly-betal3bendi
6172: bhs-24thioph-bala-betabph6172: bras-24thioph-bala-betabph
6173: bhs-24thiaz-bala-betaimid 256173: bhs-24thiaz-bala-betaimide 25
6174: ibhs-24thioph-gly-betadhbfu6174: ibhs-24thioph-gly-betadhbfu
6175 : tolhs-24thiaz-gly-betabediox6175: tolhs-24thiaz-gly-betabediox
6176: phhs-25oxaz-gly-betatrif6176: phhs-25oxaz-gly-betatrif
6177 : bhs-triaz-gly-zdap6177: bhs-triaz-gly-zdap
6178: bhs-25thiaz-gly-beta4bph6178: bhs-25thiaz-gly-beta4bph
30 6179: tolhs-25thiaz-bala-betabenfu 6180: bhs-24thiaz-gly-betaheph 6181: bhs-nme35pyr-leu-zdap 6182: impy-42nmeim-bala-betabpy 6183: bhs-25methiaz-bala-aspibua30 6179: tolhs-25thiaz-bala-betabenfu 6180: bhs-24thiaz-gly-betaheph 6181: bhs-nme35pyr-leu-zdap 6182: impy-42nmeim-bala-betabpy 6183: bhs-25methiaz-bala-aspibua
35 6184: tolhs-25thiaz-gly-betainyl 6185: tolhs-me24thioph-leu-betaph 6186: 2py-ithiadiaz-gly-zdap 6187: impy-25oxaz-gly-betafu2 6188: tolhs-me25oxaz-gly-beta34meoph 6189: thpy-24thiaz-gly-betadcph35 6184: tolhs-25thiaz-gly-betainyl 6185: tolhs-me24thioph-leu-betaph 6186: 2py-ithiadiaz-gly-zdap 6187: impy-25oxaz-gly-betafu2 6188: tolhs-me25oxaz-gly-beta34meoph 6189 24thiaz-gly-betadcph
40 6190: 2py-25oxaz-gly-aspaba 6191: tolhs-24thiaz-bala-zdap 6192: thpym-2thioph-gly-zdap 6193 : phhs-25thiaz-bala-betahcbph 6194 : ibhs-25methiaz-gly-betapyr40 6190: 2py-25oxaz-gly-aspaba 6191: tolhs-24thiaz-bala-zdap 6192: thpym-2thioph-gly-zdap 6193: phhs-25thiaz-bala-betahcbph 6194: ibhs-25methiaz-gly-betapyr
45 6195: bhs-ithiadiaz-bala-betaimid 6196 : 2py-me25thiaz-bala-betadcph 6197: bhs-25thiaz-gly-betafbph 6198: phhs-24thiaz-gly-betahcbph45 6195: bhs-ithiadiaz-bala-betaimid 6196: 2py-me25thiaz-bala-betadcph 6197: bhs-25thiaz-gly-betafbph 6198: phhs-24thiaz-gly-betahcbph
6199: phhs-25thiaz-gly-betabmph6199: phhs-25thiaz-gly beta mph
6200 : bhs-25oxaz-gly-betabenfu6200: bhs-25oxaz-gly-betabenfu
6201 : bhs-ithiadiaz-bala-betaanaphth 5 6202: bim-me24thioph-gly-betapy6201: bhs-ithiadiaz-bala-betaanaphth 5 6202: bim-me24thioph-gly-betapy
6203: bhs-24thioph-ala-beta3quin6203: bhs-24thioph-ala-beta3quin
6204 : tolhs-25oxaz-bala-betahdbph6204: tolhs-25oxaz-bala-betahdbph
6205: bhs-oxadiaz-gly-psdap6205: bhs-oxadiaz-gly-psdap
6206: bhs-25oxaz-bala-betatos6206: bras-25oxaz-bala-betatos
6207: ibhs-oxadiaz-bala-betapyr6207: ibhs-oxadiaz-bala-betapyr
1010
6208 : tolhs-me24thiaz-bala-beta34meoph6208: tolhs-me24thiaz-bala-beta34meoph
6209: 2pmhs-25methiaz-gly-betameph6209: 2 pmhs-25methiaz-gly-betameph
6210: phhs-25oxaz-gly-betah35dc6210: phhs-25oxaz-gly-betah35dc
6211: hyd-42pym-gly-psdap6211: hyd-42pym-gly-psdap
6212: ibhs-ithiadiaz-gly-betaet 15 6213: 2py-me24thioph-gly-betapy6212: ibhs-ithiadiaz-gly-betet 15 6213: 2py-me24thioph-gly-betapy
6214: phhs-24thiaz-gly-betahbcph6214: phhs-24thiaz-gly-betahbcph
6215 : phhs-oxadiaz-bala-zdap6215: phhs-oxadiaz-bala-zdap
6216 : phhs-ithiadiaz-bala-betapyr6216: phhs-ithiadiaz-bala-betapyr
6217 : phhs-24thioph-gly-asppha 20 6218: bhs-24thioph-bala-betaanaphth6217: phhs-24thioph-gly-asppha 20 6218: bhs-24thioph-bala-betaanaphth
6219: bhs-24thiaz-bala-betahbcph6219: bras-24thiaz-bala-betahbcph
6220: 2py-25methiaz-bala-zdap6220: 2py-25methiaz-bala-zdap
6221: bhs-ithiadiaz-gly-betadbph6221: bhs-ithiadiaz-gly-betadbph
6222 : 2pmhs-25methiaz-gly-betahbcph6222: 2 pmhs-25methiaz-gly-betahbcph
6223: bhs-ithiadiaz-gly-betabpy6223: bhs-ithiadiaz-gly-betabpy
2525
6224: bim-25thiaz-bala-betafphe6224: bim-25thiaz-bala-betafphe
6225: phhs-24thiaz-bala-betahbcph6225: phhs-24thiaz-bala-betahbcph
6226: ibhs-24thiaz-bala-betaimid6226: ibhs-24thiaz-bala-betaimid
6227: bhs-25thiaz-bala-betadtrif6227: bras-25thiaz-bala-betadtrif
6228: bhs-35fur-ala-zdap 30 6229: bhs-ithiadiaz-bala-aspaba6228: bhs-35fur-ala-zdap 30 6229: bhs-ithiadiaz-bala-aspaba
6230: bhs-24thiaz-bala-betapytb6230: bras-24thiaz-bala-betapytb
6231: tolhs-25oxaz-bala-beta23meoph6231: tolhs-25oxaz-bala-beta23meoph
6232: bim-24thioph-bala-betafphe6232: bim-24thioph-bala-betafphe
6233 : ibhs-24thioph-bala-betadcphtb 35 6234: bim-triaz-leu-zdap6233: ibhs-24thioph-bala-betadcphtb 35 6234: bim-triaz-leu-zdap
6235: tolhs-25methiaz-bala-aspaba6235: tolhs-25methiaz-bala-aspaba
6236: bhs-25oxaz-gly-zdapee6236: bras-25oxaz-gly-zdapee
6237: bhs-nme35pyr-bala-betadhbfu6237: bhs-nme35pyr-bala-betadhbfu
6238: ibhs-25oxaz-gly-betainyl6238: ibhs-25oxaz-gly-betainyl
6239: phhs-me24thiaz-leu-betapy6239: phhs-me24thiaz-leu-betapy
40 6240: phhs-nme35pyr-bala-betatrif40 6240: phhs-nme35pyr-bala-betatrif
6241: bhs-nme35pyr-gly-betapych6241: bhs-nme35pyr-gly-betapych
6242: bim-nme35pyr-gly-psdap6242: bim-nme35pyr-gly-psdap
6243: phhs-ithiadiaz-gly-zdapch6243: phhs-ithiadiaz-gly-zdapch
6244: bhs-42oxaz-gly-psdap 45 6245: bhs-me24thiaz-ala-psdap6244: bhs-42oxaz-gly-psdap 45 6245: bhs-me24thiaz-ala-psdap
6246 : tolhs-25methiaz-bala-betaet6246: tolhs-25methiaz-bala-betaet
6247: bhs-me24oxaz-bala-betadcph 6248: phhs-25methiaz-bala-betaoxope6247: bras-me24oxaz-bala-betadcph 6248: phhs-25methiaz-bala-betaoxope
6249 : bhs-oxadiaz-gly-betabthioph6249: bhs-oxadiaz-gly-betabthioph
6250: tolhs-25methiaz-gly-betahdbph6250: tolhs-25methiaz-gly-betahdbph
6251: phhs-oxadiaz-gly-betabph 5 6252: ibhs-ithiadiaz-gly-betaphethioa6251: phhs-oxadiaz-gly-betabph 5 6252: ibhs-ithiadiaz-gly-betaphethioa
6253 : tolhs-25oxaz-bala-beta35dbph6253: tolhs-25oxaz-bala-beta35dbph
6254: tolhs-24thiaz-gly-betadbph6254: tolhs-24thiaz-gly-betadbph
6255: ibhs-25oxaz-gly-betafbph6255: ibhs-25oxaz-gly-betafbph
6256: impy-25thiaz-bala-betainyl6256: impy-25thiaz-bala-betainyl
6257: 2py-24thioph-gly-zdap6257: 2py-24thioph-gly-zdap
10 6258 : phhs-oxadiaz-gly-psdaptb10 6258: phhs-oxadiaz-gly-psdaptb
6259: dhthi-25thiaz-bala-betadcph6259: dhthi-25thiaz-bala-betadcph
6260: ibhs-24thiaz-gly-betafu36260: ibhs-24thiaz-gly-betafu3
6261: phhs-me24oxaz-ala-betadcph6261: phhs-me24oxaz-ala-betadcph
6262 : bhs-ithiadiaz-bala-betadtrif 15 6263: bhs-ithiadiaz-nmgly-beta34meoph6262: bhs-ithiadiaz-bala-betadtrif 15 6263: bhs-ithiadiaz-nmgly-beta34meoph
6264: bhs-24thiaz-gly-betapytb6264: bhs-24thiaz-gly-betapytb
6265: 2py-24thioph-ala-psdap6265: 2py-24thioph-ala-psdap
6266: nmhs-26py-gly-betapy6266: nmhs-26py-gly-betapy
6267 : bim-26py-ala-psdap 20 6268: gua-26py-gly-betamesu6267: bim-26py-ala-psdap 20 6268: gua-26py-gly-betamesu
6269: 2py-oxadiaz-bala-aspbzla6269: 2py-oxadiaz-bala-aspbzla
6270 : phhs-24thioph-bala-betadcphch6270: phhs-24thioph-bala-betadcphch
6271: gua-42pym-gly-betacbph6271: gua-42pym-gly-betacbph
6272: bhs-24thiaz-bala-betabpy6272: bras-24thiaz-bala-betabpy
6273 : phhs-ithiadiaz-bala-betainyl6273: phhs-ithiadiaz-bala-betainyl
25 6274 : phhs-ithiadiaz-gly-betadcphch25 6274: phhs-ithiadiaz-gly-betadcphch
6275: phhs-25thiaz-bala-betahph6275: phhs-25thiaz-bala-betahph
6276: ibhs-25methiaz-bala-betapyee6276: ibhs-25methiaz-bala-betapyee
6277: ibhs-24thiaz-gly-aspbzla6277: ibhs-24thiaz-gly-aspbzla
6278: phhs-24thiaz-bala-betaoxope 30 6279: ibhs-24thioph-bala-betaphethioa6278: phhs-24thiaz-bala-betaoxope 30 6279: ibhs-24thioph-bala-betaphethioa
6280 : tolhs-ithiadiaz-gly-betamethi6280: tolhs-ithiadiaz-gly-betamethi
6281: bim-24thiaz-gly-betainyl6281: bim-24thiaz-gly-betainyl
6282: phhs-25oxaz-bala-betapym6282: phhs-25oxaz-bala-betapym
6283: tolhs-me24oxaz-bala-zdap 35 6284: bhs-25thioph-bala-betapy6283: tolhs-me24oxaz-bala-zdap 35 6284: bhs-25thioph-bala-betapy
6285: tolhs-24thioph-bala-betaimid6285: tolhs-24thioph-bala-betaimid
6286: bim-25thiaz-gly-aspbzla6286: bim-25thiaz-gly-aspbzla
6287 : tolhs-ithiadiaz-gly-betadtrif6287: tolhs-ithiadiaz-gly-betadtrif
6288: ibhs-24thiaz-bala-betaftrif6288: ibhs-24thiaz-bala-betaftrif
6289: 2py-thiadiaz-bala-psdap6289: 2py-thiadiaz-bala-psdap
40 6290: phhs-25oxaz-bala-betabmph40 6290: phhs-25oxaz-bala-betabmph
6291: phhs-nme35pyr-gly-betahmph6291: phhs-nme35pyr-gly-betahmph
6292: 2py-53pyrazo-gly-betadcph6292: 2py-53pyrazo-gly-betadcph
6293: bhs-me24thiaz-leu-psdap6293: bhs-me24thiaz-leu-psdap
6294 : bim-24im-gly-betadcph 45 6295: 2py-24oxaz-ala-betameph6294: bim-24im-gly-betadcph 45 6295: 2py-24oxaz-ala-betameph
6296: tolhs-24thiaz-gly-betahbcph6296: tolhs-24thiaz-gly-betahbcph
6297 : phhs-25methiaz-bala-beta35dbph 6298: phhs-25thiaz-gly-betapyr6297: phhs-25methiaz-bala-beta35dbph 6298: phhs-25thiaz-gly-betapyr
6299: ibhs-25thiaz-bala-betadbph6299: ibhs-25thiaz-bala-betadbph
6300 : bhs-nme35pyr-bala-betaet6300: bhs-nme35pyr-bala-betaet
6301: bim-me25thiaz-gly-zdap 5 6302: phhs-25thiaz-bala-betaanaphth6301: bim-me25thiaz-gly-zdap 5 6302: phhs-25thiaz-bala-betaanaphth
6303: bhs-nme35pyr-gly-betaol6303: bhs-nme35pyr-gly-betaol
6304 : phhs-24thioph-bala-betadtrif6304: phhs-24thioph-bala-betadtrif
6305: phhs-me25thiaz-leu-beta34meoph6305: phhs-me25thiaz-leu-beta34meoph
6306: ibhs-25thiaz-gly-betamethi6306: ibhs-25thiaz-gly-betamethi
6307: bim-24thioph-leu-zdap6307: bim-24thioph-leu-zdap
1010
6308: bhs-ithiadiaz-bala-betathio36308: bhs-ithiadiaz-bala-betathio3
6309: 2pmhs-24thiaz-gly-betabpy6309: 2 pmhs-24thiaz-gly-betabpy
6310: bhs-24thiaz-gly-betapym6310: bhs-24thiaz-gly-betapym
6311: phhs-25methiaz-gly-betampy6311: phhs-25methiaz-gly-betampy
6312: bim-25oxaz-bala-asppha 15 6313: impy-42nmeim-gly-betamethioph6312: bim-25oxaz-bala-asppha 15 6313: impy-42nmeim-gly-betamethioph
6314: tolhs-nme35pyr-bala-betahcbph6314: tolhs-nme35pyr-bala-betahcbph
6315 : bhs-oxadiaz-bala-betabnaphth6315: bras-oxadiaz-bala-betabnaphth
6316: bhs-nme35pyr-gly-betaipr6316: bhs-nme35pyr-gly-betaipr
6317: ibhs-24thiaz-bala-betahc 20 6318: tolhs-25methiaz-gly-betaanaphth6317: ibhs-24thiaz-bala-betahc 20 6318: tolhs-25methiaz-gly-betaanaphth
6319: 2py-me25thioph-bala-betaph6319: 2py-me25thioph-bala-betaph
6320 : tolhs-24thioph-gly-betapych6320: tolhs-24thioph-gly-betapych
6321: ibhs-oxadiaz-gly-betabenfu6321: ibhs-oxadiaz-gly-betabenfu
6322: phhs-25thiaz-gly-betamesu6322: phhs-25thiaz-gly-betamesu
6323 : tolhs-me24thioph-bala-betaph6323: tolhs-me24thioph-bala-betaph
25 6324 : dimethpym-26py-gly-betahdcph25 6324: dimethpym-26py-gly-betahdcph
6325: ibhs-25thiaz-gly-beta34meoph6325: ibhs-25thiaz-gly-beta34meoph
6326: bim-me25thiaz-gly-betapy6326: bim-me25thiaz-gly-betapy
6327: phhs-24thioph-gly-betapym6327: phhs-24thioph-gly-betapym
6328: 2py-me25thiaz-ala-beta34meoph 30 6329: phhs-oxadiaz-bala-betadbph6328: 2py-me25thiaz-ala-beta34meoph 30 6329: phhs-oxadiaz-bala-betadbph
6330: ibhs-nme35pyr-bala-betafbph6330: ibhs-nme35pyr-bala-betafbph
6331: ibhs-25thiaz-bala-betatrif6331: ibhs-25thiaz-bala-betatrif
6332: tolhs-oxadiaz-gly-betaipr6332: tolhs-oxadiaz-gly-betaipr
6333: bim-me25thiaz-bala-betapy 35 6334: bhs-25oxaz-gly-betahc6333: bim-me25thiaz-bala-betapy 35 6334: bhs-25oxaz-gly-betahc
6335 : ibhs-24thioph-bala-betadtrif6335: ibhs-24thioph-bala-betadtrif
6336: bhs-nme35pyr-gly-betahmo6336: bhs-nme35pyr-gly-betahmo
6337: 2py-52thiaz-gly-betadcph6337: 2py-52thiaz-gly-betadcph
6338: bhs-35fur-leu-betadcph6338: bras-35fur-leu-betadcph
6339: dhim-26py-gly-betainyl6339: dhim-26py-gly-betainyl
40 6340: bim-me24thiaz-ala-zdap40 6340: bim-me24thiaz-ala-zdap
6341: ibhs-nme35pyr-gly-betamesu6341: ibhs-nme35pyr-gly-betamesu
6342: ibhs-oxadiaz-bala-aspibua6342: ibhs-oxadiaz-bala-aspibua
6343: tolhs-24thiaz-bala-psdapee6343: tolhs-24thiaz-bala-psdapee
6344: bim-me24oxaz-bala-psdap 45 6345: bhs-me24thioph-gly-psdap6344: bim-me24oxaz-bala-psdap 45 6345: bhs-me24thioph-gly-psdap
6346: bhs-24thioph-gly-betaet6346: bhs-24thioph-gly-betaet
6347 : ibhs-ithiadiaz-bala-beta23meoph 6348: 2py-25thiaz-bala-suabu6347: ibhs-ithiadiaz-bala-beta23meoph 6348: 2py-25thiaz-bala-suabu
6349 : bhs-me24thiaz-bala-betadcph6349: bhs-me24thiaz-bala-betadcph
6350: 2py-25thiaz-bala-betaet6350: 2py-25thiaz-bala-betaet
6351: bhs-oxadiaz-gly-asppha 5 6352: ibhs-24thioph-bala-betal3bendi6351: bhs-oxadiaz-gly-asppha 5 6352: ibhs-24thioph-bala-betal3bendi
6353 : phhs-25methiaz-bala-betabnaphth6353: phhs-25methiaz-bala-betabnaphth
6354 : 2py-25thiaz-gly-betacthioph6354: 2py-25thiaz-gly-betacthioph
6355: dhim-25oxaz-bala-betadcph6355: dhim-25oxaz-bala-betadcph
6356: phhs-me24thioph-bala-psdap6356: phhs-me24thioph-bala-psdap
6357: 2py-ithiadiaz-bala-aspibua6357: 2py-ithiadiaz-bala-aspibua
10 6358: phhs-24thioph-gly-betadmoph10 6358: phhs-24thioph-gly-betadmoph
6359 : bhs-ithiadiaz-bala-betadcphch6359: bhs-ithiadiaz-bala-betadcphch
6360: ibhs-24thiaz-bala-betadmoph6360: ibhs-24thiaz-bala-betadmoph
6361 : phhs-24thioph-bala-beta4bph6361: phhs-24thioph-bala-beta4bph
6362: ibhs-25oxaz-bala-betapych 15 6363: ibhs-24thioph-bala-betabph6362: ibhs-25oxaz-bala-betapych 15 6363: ibhs-24thioph-bala-betabph
6364: bhs-25oxaz-ala-betapy6364: bhs-25oxaz-ala-betapy
6365: bim-25fur-leu-betapy6365: bim-25fur-leu-betapy
6366 : ibhs-24thioph-bala-beta35dbph6366: ibhs-24thioph-bala-beta35dbph
6367 : bhs-24thioph-bala-betaftrif 2o 6368: bhs-25fur-ala-zdap6367: bhs-24thioph-bala-betaftrif 2o 6368: bhs-25fur-ala-zdap
6369: bhs-25thiaz-bala-beta34meoph6369: bhs-25thiaz-bala-beta34meoph
6370: thazep-26py-gly-betapy6370: thazep-26py-gly-betapy
6371: bhs-nme35pyr-gly-betathio36371: bhs-nme35pyr-gly-betathio3
6372: 2pmhs-25oxaz-bala-betaoxope6372: 2 pmhs-25oxaz-bala-betaoxope
6373: tolhs-oxadiaz-gly-betacph6373: tolhs-oxadiaz-gly-betacph
25 6374 : phhs-25methiaz-bala-psdaptb25 6374: phhs-25methiaz-bala-psdaptb
6375: bim-25thiaz-nmala-betadcph6375: bim-25thiaz-nmala-betadcph
6376: bim-25thiaz-bala-aspbzla6376: bim-25thiaz-bala-aspbzla
6377: bhs-24thiaz-nmgly-betafphe6377: bhs-24thiaz-nmgly-betafphe
6378: tolhs-ithiadiaz-gly-betaph 30 6379: ibhs-ithiadiaz-bala-betaol6378: tolhs-ithiadiaz-gly-betaph 30 6379: ibhs-ithiadiaz-bala-betaol
6380 : impy-24thioph-gly-betathiobe6380: impy-24thioph-gly-betathiobe
6381 : tolhs-25methiaz-gly-betacthioph6381: tolhs-25methiaz-gly-betacthioph
6382 : ibhs-24thiaz-bala-betameph6382: ibhs-24thiaz-bala-betameph
6383: 2py-25methiaz-bala-betaet 35 6384: bhs-25oxaz-nmgly-beta34meoph6383: 2py-25methiaz-bala-betaet 35 6384: bhs-25oxaz-nmgly-beta34meoph
6385: gua-24thiaz-gly-betapy6385: gua-24thiaz-gly-betapy
6386 : tolhs-25oxaz-bala-betahcbph6386: tolhs-25oxaz-bala-betahcbph
6387 : bhs-42nmeim-bala-betacthioph6387: bhs-42nmeim-bala-betacthioph
6388 : tolhs-25methiaz-gly-betameph6388: tolhs-25methiaz-gly-betameph
6389 : ibhs-25thiaz-bala-betathiome6389: ibhs-25thiaz-bala-betathiome
40 6390 : bhs-nme35pyr-bala-betathio340 6390: bhs-nme35pyr-bala-betathio3
6391: phhs-oxadiaz-bala-betahmofu6391: phhs-oxadiaz-bala-betahmofu
6392 : ibhs-ithiadiaz-bala-betadmoph6392: ibhs-ithiadiaz-bala-betadmoph
6393: tolhs-24thiaz-gly-aspaba6393: tolhs-24thiaz-gly-aspaba
6394 : impy-25thiaz-bala-betamesu 45 6395: ibhs-24thiaz-gly-betaibph6394: impy-25thiaz-bala-betamesu 45 6395: ibhs-24thiaz-gly-betaibph
6396: bhs-25oxaz-bala-betainyl6396: bras-25oxaz-bala-betainyl
6397: bhs-25methiaz-bala-betahph 6398: gua-25thiaz-nmgly-betapy 6399: bhs-24thioph-gly-aspbzla 6400: bhs-25oxaz-nmgly-ibsdap 6401: 2py-24im-leu-zdap 6402: phhs-nme35pyr-bala-betafbph 6403: tolhs-25oxaz-bala-zdap 6404: phhs-oxadiaz-gly-betahmofu 6405: bim-42nmeim-bala-betathiobe 6406: bhs-25oxaz-bala-zdaptb 6407: ibhs-25thiaz-gly-aspbzla6397: bras-25methiaz-bala-betahph 6398: gua-25thiaz-nmgly-betapy 6399: bhs-24thioph-gly-aspbzla 6400: bhs-25oxaz-nmgly-ibsdap 6401: 2py-24im-leu-zdap 6402: phhs-nme35pyr-bala-betafbph 6403: tolhs-25az -bala-zdap 6404: phhs-oxadiaz-gly-betahmofu 6405: bim-42nmeim-bala-betathiobe 6406: bhs-25oxaz-bala-zdaptb 6407: ibhs-25thiaz-gly-aspbzla
10 6408: bim-24oxaz-bala-betapy 6409 : ibhs-25oxaz-gly-betal3bendi 6410: bhs-24thiaz-gly-betahbcph 6411 : ibhs-25methiaz-bala-betapbiph 6412 : tolhs-ithiadiaz-bala-betadito10 6408: bim-24oxaz-bala-betapy 6409: ibhs-25oxaz-gly-betal3bendi 6410: bhs-24thiaz-gly-betahbcph 6411: ibhs-25methiaz-bala-betapbiph 6412: tolhs-ithiadiaz-bala-betadito
15 6413: phhs-ithiadiaz-bala-betatrif 6414 : tolhs-24thiaz-gly-betadcphch 6415: bim-25methiaz-bala-betacph 6416 : phhs-25methiaz-gly-betamethioph 6417 : tolhs-25methiaz-gly-betapyr15 6413: phhs-ithiadiaz-bala-betatrif 6414: tolhs-24thiaz-gly-betadcphch 6415: bim-25methiaz-bala-betacph 6416: phhs-25methiaz-gly-betamethioph 6417: tolhs-25methiaz-gly-betapyr
20 6418: bhs-ithiadiaz-gly-psdaptb 6419 : ibhs-ithiadiaz-bala-betapyr 6420: phhs-24thioph-bala-betahdbph 6421: dhim-42pym-ala-betapy 6422: bhs-25thiaz-ala-betambiph 6423: 2py-24thioph-gly-asppha20 6418: bhs-ithiadiaz-gly-psdaptb 6419: ibhs-ithiadiaz-bala-betapyr 6420: phhs-24thioph-bala-betahdbph 6421: dhim-42pym-ala-betapy 6422: bhs-25thiaz-ala-betambiph 6423: 2py- 24thioph-gly-asppha
25 6424: phhs-24thiaz-bala-betafph 6425: 2py-24thiaz-bala-betaet 6426 : tolhs-ithiadiaz-bala-betahph 6427: 2py-nme35pyr-ala-betadcph 6428 : phhs-me24thioph-bala-betaph25 6424: phhs-24thiaz-bala-betafph 6425: 2py-24thiaz-bala-betet 6426: tolhs-ithiadiaz-bala-betahph 6427: 2py-nme35pyr-ala-betadcph 6428: phhs-me24thioph-bala-betaph
30 6429: bhs-25oxaz-gly-betaoxope 6430: phhs-24thiaz-gly-betaimid 6431 : tolhs-25methiaz-gly-betafphe 6432: bhs-35thioph-leu-betapy 6433 : ibhs-25thiaz-bala-betadcphch30 6429: bhs-25oxaz-gly-betaoxope 6430: phhs-24thiaz-gly-betaimide 6431: tolhs-25methiaz-gly-betafphe 6432: bhs-35thioph-leu-betapy 6433: ibhs-25thiaz-bala-betadcphch
35 6434 : tolhs-25thiaz-bala-betatbuph 6435: bhs-24im-gly-betadcph 6436: 2py-26py-gly-betameph 6437: hs-25thioph-gly-zdap 6438: phhs-me24oxaz-gly-zdap 6439: tolhs-25oxaz-bala-betadhbfu35 6434: tolhs-25thiaz-bala-betatbuph 6435: bhs-24im-gly-betadcph 6436: 2py-26py-gly-betameph 6437: hs-25thioph-gly-zdap 6438: phhs-me24oxaz-gly-zdap 6439: tolhs- 25oxaz-bala-betadhbfu
40 6440: bhs-24thioph-bala-betabdimo 6441 : ibhs-ithiadiaz-bala-betahdbph 6442: phhs-24thioph-bala-betapym 6443 : phhs-25methiaz-gly-betadcphee 6444: bhs-25methiaz-gly-betahph40 6440: bhs-24thioph-bala-betabdimo 6441: ibhs-ithiadiaz-bala-betahdbph 6442: phhs-24thioph-bala-betapym 6443: phhs-25methiaz-gly-betadcphee 6444: bhs-25methiaz-gly-betahph
45 6445: phhs-24thiaz-bala-betaheph 6446: bhs-25oxaz-gly-betaoxaz 6447: bhs-24thiaz-bala-aspibua 6448 : phhs-ithiadiaz-gly-betabthioph45 6445: phhs-24thiaz-bala-betaheph 6446: bhs-25oxaz-gly-betaoxaz 6447: bhs-24thiaz-bala-aspibua 6448: phhs-ithiadiaz-gly-betabthioph
6449: agua-26py-gly-betainyl6449: agua-26py-gly-betainyl
6450: phhs-24thioph-gly-betahmofu6450: phhs-24thioph-gly-betahmofu
6451: bhs-oxadiaz-bala-betatrif 5 6452: bhs-me24thioph-ala-betaph6451: bhs-oxadiaz-bala-betatrif 5 6452: bhs-me24thioph-ala-betaph
6453 : tolhs-25methiaz-gly-betabediox6453: tolhs-25methiaz-gly-betabediox
6454: tolhs-24thioph-bala-betabediox6454: tolhs-24thioph-bala-betabediox
6455: bhs-24thioph-gly-betambiph6455: bhs-24thioph-gly-betambiph
6456: bim-35fur-leu-betapy6456: bim-35fur-leu-betapy
6457: phhs-24thiaz-gly-csdap6457: phhs-24thiaz-gly-csdap
1010
6458: agua-42nmeim-gly-betapy6458: agua-42nmeim-gly-betapy
6459: tolhs-me24thioph-ala-psdap6459: tolhs-me24thioph-ala-psdap
6460 : tolhs-ithiadiaz-bala-betabdimo6460: tolhs-ithiadiaz-bala-betabdimo
6461: tolhs-me25oxaz-gly-betaph6461: tolhs-me25oxaz-gly-betaph
6462: 2py-oxadiaz-gly-asppha 15 6463: tolhs-25thiaz-gly-betahph6462: 2py-oxadiaz-gly-asppha 15 6463: tolhs-25thiaz-gly-betahph
6464: bhs-nme35pyr-gly-betahdbph6464: bhs-nme35pyr-gly-betahdbph
6465: bhs-24thiaz-gly-ibsdap6465: bhs-24thiaz-gly-ibsdap
6466 : phhs-nme35pyr-gly-beta4bph6466: phhs-nme35pyr-gly-beta4bph
6467: bhs-25oxaz-bala-betathiome 20 6468: tolhs-25thiaz-bala-betaamibe6467: bhs-25oxaz-bala-betathiome 20 6468: tolhs-25thiaz-bala-betaamibe
6469: tolhs-25oxaz-bala-zdapee6469: tolhs-25oxaz-bala-zdapee
6470: impy-25thiaz-bala-betaftrif6470: impy-25thiaz-bala-betaftrif
6471 : tolhs-25oxaz-gly-betadcphtb6471: tolhs-25oxaz-gly-betadcphtb
6472: bhs-me24thioph-bala-psdap6472: bhs-me24thioph-bala-psdap
6473: bhs-nme35pyr-nmgly-betathio36473: bhs-nme35pyr-nmgly-betathio3
25 6474: bhs-oxadiaz-gly-betapym25 6474: bhs-oxadiaz-gly-betapym
6475: phhs-24thioph-gly-betadito6475: phhs-24thioph-gly-betadito
6476: ibhs-25oxaz-bala-betapbiph6476: ibhs-25oxaz-bala-betapbiph
6477 : tolhs-nme35pyr-bala-betatrif6477: tolhs-nme35pyr-bala-betatrif
6478: bhs-25methiaz-bala-beta34dcph 30 6479: bim-25methiaz-gly-betadmph6478: bhs-25methiaz-bala-beta34dcph 30 6479: bim-25methiaz-gly-betadmph
6480: phhs-25methiaz-gly-betahc6480: phhs-25methiaz-gly-betahc
6481 : tolhs-24thiaz-bala-betah35dc6481: tolhs-24thiaz-bala-betah35dc
6482: bhs-me25thioph-ala-betaph6482: bhs-me25thioph-ala-betaph
6483: tolhs-oxadiaz-gly-betahmph 35 6484: tolhs-25thiaz-bala-betatos6483: tolhs-oxadiaz-gly-betahmph 35 6484: tolhs-25thiaz-bala-betatos
6485: tolhs-ithiadiaz-gly-betaol6485: tolhs-ithiadiaz-gly-betaol
6486 : tolhs-24thioph-bala-betadmoph6486: tolhs-24thioph-bala-betadmoph
6487: tolhs-oxadiaz-gly-betainyl6487: tolhs-oxadiaz-gly-betainyl
6488 : phhs-25methiaz-bala-beta4bph6488: phhs-25methiaz-bala-beta4bph
6489: bim-thiadiaz-ala-betadcph6489: bim-thiadiaz-ala-betadcph
40 6490: ur-25methiaz-gly-betadcph40 6490: ur-25methiaz-gly-betadcph
6491: bim-42nmeim-nmgly-zdap6491: bim-42nmeim-nmgly-zdap
6492: tolhs-24thiaz-bala-betaph6492: tolhs-24thiaz-bala-betaph
6493 : ibhs-24thioph-gly-betapyee6493: ibhs-24thioph-gly-betapyee
6494: thazep-24oxaz-gly-betainyl 45 6495: 4pmhs-25thiaz-bala-betameph6494: thazep-24oxaz-gly-betainyl 45 6495: 4 pmhs-25thiaz-bala-betameph
6496: ibhs-25methiaz-gly-suabu6496: ibhs-25methiaz-gly-suabu
6497: tolhs-25thiaz-bala-betapym 6498 : bhs-oxadiaz-gly-beta23meoph6497: tolhs-25thiaz-bala-betapym 6498: bhs-oxadiaz-gly-beta23meoph
6499: tolhs-nme35pyr-gly-psdap6499: tolhs-nme35pyr-gly-psdap
6500: 2pmhs-42nmeim-gly-betahmo6500: 2 pmhs-42nmeim-gly-betahmo
6501 : phhs-ithiadiaz-bala-betaomebendi 5 6502: bhs-me24thiaz-ala-beta34meoph6501: phhs-ithiadiaz-bala-betaomebendi 5 6502: bhs-me24thiaz-ala-beta34meoph
6503: bhs-24thiaz-bala-beta3quin6503: bhs-24thiaz-bala-beta3quin
6504 : phhs-25methiaz-gly-betathioph6504: phhs-25methiaz-gly-betathioph
6505: tolhs-me25oxaz-gly-betapy6505: tolhs-me25oxaz-gly-betapy
6506: phhs-24thioph-gly-betapyr6506: phhs-24thioph-gly-betapyr
6507: tolhs-25oxaz-bala-betapym6507: tolhs-25oxaz-bala-betapym
10 6508: bhs-ithiadiaz-gly-betaph10 6508: bhs-ithiadiaz-gly-betaph
6509: bim-25oxaz-leu-psdap6509: bim-25oxaz-leu-psdap
6510 : impy-24thioph-bala-betaftrif6510: impy-24thioph-bala-betaftrif
6511: phhs-24thioph-gly-betah35dc6511: phhs-24thioph-gly-betah35dc
6512: ibhs-24thiaz-gly-betadmoph 15 6513: bhs-42oxaz-ala-betapy6512: ibhs-24thiaz-gly-betadmoph 15 6513: bhs-42oxaz-ala-betapy
6514: thazep-42nmeim-bala-betameph6514: thazep-42nmeim-bala-betameph
6515: bhs-24thiaz-bala-busu2be6515: bhs-24thiaz-bala-busu2be
6516: gua-25thiaz-gly-betahph6516: gua-25thiaz-gly-betahph
6517: gua-24thiaz-gly-betainyl 20 6518: bhs-25thiaz-gly-betahmofu6517: gua-24thiaz-gly-betainyl 20 6518: bhs-25thiaz-gly-betahmofu
6519: phhs-nme35pyr-gly-betahmo6519: phhs-nme35pyr-gly-betahmo
6520: bhs-25thiaz-gly-betaamibe6520: bhs-25thiaz-gly-betaamibe
6521: phhs-24thioph-gly-betapy6521: phhs-24thioph-gly-betapy
6522: bhs-oxadiaz-gly-betadmph6522: bhs-oxadiaz-gly-betadmph
6523 : tolhs-me24oxaz-ala-betadcph6523: tolhs-me24oxaz-ala-betadcph
25 6524: thazep-25methiaz-bala-zdap25 6524: thazep-25methiaz-bala-zdap
6525: tolhs-ithiadiaz-bala-aspibua6525: tolhs-ithiadiaz-bala-aspibua
6526: phhs-me25oxaz-bala-zdap6526: phhs-me25oxaz-bala-zdap
6527: phhs-nme35pyr-gly-betadito6527: phhs-nme35pyr-gly-betadito
6528: 2py-24oxaz-bala-psdap 30 6529: bhs-25methiaz-bala-beta35dbph6528: 2py-24oxaz-bala-psdap 30 6529: bhs-25methiaz-bala-beta35dbph
6530: phhs-24thioph-bala-zdaptb6530: phhs-24thioph-bala-zdaptb
6531: bhs-35fur-gly-betadcph6531: bras-35fur-gly-betadcph
6532 : phhs-25thiaz-gly-beta34meoph6532: phhs-25thiaz-gly-beta34meoph
6533 : phhs-25thiaz-gly-betaphethio 35 6534: agua-24oxaz-gly-betainyl6533: phhs-25thiaz-gly-betaphethio 35 6534: agua-24oxaz-gly-betainyl
6535: phhs-25oxaz-bala-betahc6535: phhs-25oxaz-bala-betahc
6536: 2py-53pyrazo-leu-zdap6536: 2py-53pyrazo-leu-zdap
6537 : ibhs-25methiaz-bala-aspibua6537: ibhs-25methiaz-bala-aspibua
6538: 2py-24thiaz-gly-betapy6538: 2py-24thiaz-gly-betapy
6539 : tolhs-ithiadiaz-gly-betaphethio6539: tolhs-ithiadiaz-gly-betaphethio
40 6540: ibhs-oxadiaz-bala-betaipr40 6540: ibhs-oxadiaz-bala-betaipr
6541: bhs-25thiaz-gly-betathio36541: bhs-25thiaz-gly-betathio3
6542: gua-24oxaz-gly-betacbph6542: gua-24oxaz-gly-betacbph
6543: bhs-24oxaz-gly-betapy6543: bhs-24oxaz-gly-betapy
6544 : tolhs-24thioph-bala-betafu2 45 6545: phhs-24thioph-gly-betamethi6544: tolhs-24thioph-bala-betafu2 45 6545: phhs-24thioph-gly-betamethi
6546 : bhs-nme35pyr-bala-beta34dcph6546: bhs-nme35pyr-bala-beta34dcph
6547 : phhs-oxadiaz-bala-betaheph 6548: 2py-oxadiaz-gly-betapy6547: phhs-oxadiaz-bala-betaheph 6548: 2py-oxadiaz-gly-betapy
6549: bhs-25methiaz-nmgly-betameph6549: bhs-25methiaz-nmgly-betameph
6550: 2py-me24oxaz-ala-betadcph6550: 2py-me24oxaz-ala-betadcph
6551: bim-triaz-ala-psdap 5 6552: ibhs-25thiaz-gly-betabenfu6551: bim-triaz-ala-psdap 5 6552: ibhs-25thiaz-gly-betabenfu
6553 : bim-42nmeim-bala-betapy6553: bim-42nmeim-bala-betapy
6554 : bhs-25thiaz-gly-betabnaphth6554: bhs-25thiaz-gly-betabnaphth
6555 : bhs-ithiadiaz-bala-betadhbfu6555: bhs-ithiadiaz-bala-betadhbfu
6556: tolhs-25thiaz-gly-betaipro6556: tolhs-25thiaz-gly-betaipro
6557: dhpyrr-26py-gly-psdap6557: dhpyrr-26py-gly-psdap
10 6558: bhs-24thiaz-ala-betadcph10 6558: bhs-24thiaz-ala-betadcph
6559: hs-25thiaz-gly-betainyl6559: hs-25thiaz-gly-betainyl
6560: bhs-25oxaz-gly-betamethi6560: bhs-25oxaz-gly-betamethi
6561 : bhs-nme35pyr-bala-beta34meoph6561: bhs-nme35pyr-bala-beta34meoph
6562 : ibhs-25methiaz-bala-betaomebendi 15 6563: phhs-24thioph-gly-betadcphtb6562: ibhs-25methiaz-bala-betaomebendi 15 6563: phhs-24thioph-gly-betadcphtb
6564: ibhs-25thiaz-gly-betatbuph6564: ibhs-25thiaz-gly-betatbuph
6565: ibhs-oxadiaz-gly-betafluo6565: ibhs-oxadiaz-gly-betafluo
6566: 2pmhs-24thiaz-phe-zdap6566: 2 pmhs-24thiaz-phe-zdap
6567: ibhs-24thioph-gly-betabph 20 6568: 2py-42nmeim-gly-betaimid6567: ibhs-24thioph-gly-betabph 20 6568: 2py-42nmeim-gly-betaimid
6569: ibhs-25methiaz-gly-betahni6569: ibhs-25methiaz-gly-betahni
6570 : phhs-25methiaz-bala-psdapch6570: phhs-25methiaz-bala-psdapch
6571: phhs-25oxaz-gly-betabpy6571: phhs-25oxaz-gly-betabpy
6572 : bhs-24thiaz-nmgly-betal3bendi6572: bhs-24thiaz-nmgly-betal3bendi
6573 : ibhs-oxadiaz-gly-betabediox6573: ibhs-oxadiaz-gly-betabediox
25 6574: ibhs-nme35pyr-gly-betacph25 6574: ibhs-nme35pyr-gly-betacph
6575: bim-24im-leu-psdap6575: bim-24im-leu-psdap
6576 : bim-25thiaz-gly-betaomebendi6576: bim-25thiaz-gly-betaomebendi
6577: tolhs-oxadiaz-gly-zdapee6577: tolhs-oxadiaz-gly-zdapee
6578: ibhs-24thioph-gly-betahcbph 30 6579: ibhs-25methiaz-bala-betainyl6578: ibhs-24thioph-gly-betahcbph 30 6579: ibhs-25methiaz-bala-betainyl
6580: ibhs-ithiadiaz-bala-zdapee6580: ibhs-ithiadiaz-bala-zdapee
6581: tolhs-ithiadiaz-bala-betahc6581: tolhs-ithiadiaz-bala-betahc
6582: tolhs-24thioph-gly-betamesu6582: tolhs-24thioph-gly-betamesu
6583: tolhs-24thiaz-bala-suabu 35 6584: bhs-24im-ala-betadcph6583: tolhs-24thiaz-bala-suabu 35 6584: bhs-24im-ala-betadcph
6585: gua-24thiaz-gly-beta4bph6585: gua-24thiaz-gly-beta4bph
6586: bhs-25thiaz-bala-betaipr6586: bhs-25thiaz-bala-betaipr
6587: ibhs-25oxaz-gly-betabnaphth6587: ibhs-25oxaz-gly-betabnaphth
6588: ibhs-nme35pyr-gly-betadito6588: ibhs-nme35pyr-gly-betadito
6589: bim-me25thiaz-ala-zdap6589: bim-me25thiaz-ala-zdap
40 6590: bhs-24thioph-bala-zdapee40 6590: bhs-24thioph-bala-zdapee
6591: ibhs-oxadiaz-gly-betafu26591: ibhs-oxadiaz-gly-betafu2
6592: 2py-me25thiaz-leu-betapy6592: 2py-me25thiaz-leu-betapy
6593: phhs-24thiaz-bala-betaipr6593: phhs-24thiaz-bala-betaipr
6594 : tolhs-ithiadiaz-bala-betafluo 45 6595: ibhs-24thioph-bala-betaamibe6594: tolhs-ithiadiaz-bala-betafluo 45 6595: ibhs-24thioph-bala-betaamibe
6596: 2py-25thioph-gly-betapy6596: 2py-25thioph-gly-betapy
6597: bhs-25oxaz-leu-betapy 6598 : tolhs-ithiadiaz-gly-betaamibe 6599: bhs-me24oxaz-leu-betadcph 6600: bhs-nme35pyr-bala-betafluo 6601: bhs-24thiaz-ala-betabpy 6602 : ibhs-25methiaz-bala-betaipr 6603: bhs-24thiaz-bala-betadhbfu 6604 : tolhs-25thiaz-gly-betal3bendi 6605: phhs-nme35pyr-gly-betadcphee 6606: bhs-25oxaz-gly-betabmph 6607: phhs-25methiaz-gly-betaipr6597: bras-25oxaz-leu-betapy 6598: tolhs-ithiadiaz-gly-betaamibe 6599: bhs-me24oxaz-leu-betadcph 6600: bhs-nme35pyr-bala-betafluo 6601: bhs-24thiaz-ala-betabpy 6602: ibhs-25methiaz-bala-betaiprs 6603 -bala-betadhbfu 6604: tolhs-25thiaz-gly-betal3bendi 6605: phhs-nme35pyr-gly-betadcphee 6606: bhs-25oxaz-gly-betabmph 6607: phhs-25methiaz-gly-betaipr
10 6608: tolhs-25oxaz-gly-betaftrif 6609: bhs-25oxaz-bala-betaphethioa 6610: ibhs-24thioph-gly-betaheph 6611: bhs-24thioph-gly-suabu 6612 : tolhs-25methiaz-bala-betamethioph10 6608: tolhs-25oxaz-gly-betaftrif 6609: bhs-25oxaz-bala-betaphethioa 6610: ibhs-24thioph-gly-betaheph 6611: bhs-24thioph-gly-suabu 6612: tolhs-25methiaz-bala-betamethioph
15 6613: tolhs-24thioph-gly-asppha 6614: ibhs-25methiaz-bala-betaol 6615: phhs-24thiaz-bala-betapytb 6616: 2pmhs-42nmeim-bala-betafu2 6617: tolhs-oxadiaz-gly-aspibua15 6613: tolhs-24thioph-gly-asppha 6614: ibhs-25methiaz-bala-betaol 6615: phhs-24thiaz-bala-betapytb 6616: 2 pmhs-42nmeim-bala-betafu2 6617: tolhs-oxadiaz-gly-aspibua
20 6618: bhs-oxadiaz-nmgly-ibsdap 6619: tolhs-24thioph-gly-betapym 6620: ibhs-nme35pyr-bala-betahmofu 6621: bhs-35thioph-bala-zdap 6622: 2pmhs-25methiaz-gly-betahb 6623: gua-26py-gly-betah35dc 6624: phhs-24thiaz-gly-betapytb 6625 : bim-42nmeim-gly-betaphethioa 6626: 2py-triaz-gly-zdap 6627: bhs-24thiaz-gly-zdap 6628: bhs-24thiaz-bala-betampy20 6618: bhs-oxadiaz-nmgly-ibsdap 6619: tolhs-24thioph-gly-betapym 6620: ibhs-nme35pyr-bala-betahmofu 6621: bhs-35thioph-bala-zdap 6622: 2 pmhs-25methiaz-gly-betahb 6623: gua- 26py-gly-betah35dc 6624: phhs-24thiaz-gly-betapytb 6625: bim-42nmeim-gly-betaphethioa 6626: 2py-triaz-gly-zdap 6627: bhs-24thiaz-gly-zdap 6628: bhs-24thiaz-bala-betampy
30 6629: bim-25oxaz-gly-asppha30 6629: bim-25oxaz-gly-asppha
6630 : tolhs-ithiadiaz-bala-beta35dbph 6631: phhs-nme35pyr-bala-asppha 6632: ibhs-oxadiaz-gly-betadhbfu 6633 : ibhs-ithiadiaz-bala-betadcphch6630: tolhs-ithiadiaz-bala-beta35dbph 6631: phhs-nme35pyr-bala-asppha 6632: ibhs-oxadiaz-gly-betadhbfu 6633: ibhs-ithiadiaz-bala-betadcphch
35 6634: 2py-ithiadiaz-gly-aspaba 6635: bhs-25oxaz-nmgly-beta3quin 6636: ibhs-25oxaz-bala-zdapee 6637: bhs-25oxaz-gly-betabthioph 6638: bhs-oxadiaz-gly-betabph 6639: phhs-oxadiaz-bala-betameph35 6634: 2py-ithiadiaz-gly-aspaba 6635: bhs-25oxaz-nmgly-beta3quin 6636: ibhs-25oxaz-bala-zdapee 6637: bhs-25oxaz-gly-betabthioph 6638: bhs-oxadiaz-gly-betabph 6639: phhs- oxadiaz-bala-betameph
40 6640 : tolhs-me25thioph-bala-betapy 6641 : tolhs-ithiadiaz-gly-betahdbph 6642: bim-24thiaz-gly-betadcph 6643 : ibhs-nme35pyr-gly-betaphethioa 6644: tolhs-25thiaz-gly-betathio340 6640: tolhs-me25thioph-bala-betapy 6641: tolhs-ithiadiaz-gly-betahdbph 6642: bim-24thiaz-gly-betadcph 6643: ibhs-nme35pyr-gly-betaphethioa 6644: tolhs-25thiaz-gly-betathio3
45 6645: phhs-24thioph-bala-betapych 6646: 2py-35fur-leu-betapy 6647: bhs-24chin-gly-zdap 6648: tolhs-oxadiaz-gly-betaamibe 6649: bhs-24thioph-nmgly-betahph 6650: ibhs-oxadiaz-gly-betabdimo 6651: 2py-me24oxaz-gly-beta34meoph 6652: bhs-25thiaz-gly-betaimid 6653: bim-24thiaz-ala-betadcph 6654: tolhs-25oxaz-gly-zdap 6655: bhs-ithiadiaz-gly-betacbph 6656: tolhs-nme35pyr-gly-betal3bendi 6657: 2py-thiadiaz-bala-betapy45 6645: phhs-24thioph-bala-betapych 6646: 2py-35fur-leu-betapy 6647: bhs-24chin-gly-zdap 6648: tolhs-oxadiaz-gly-betaamibe 6649: bhs-24thioph-nmgly-betahph 6650: ibhs-oxadiaz-gly-betabdimo 6651: 2py-me24oxaz-gly-beta34meoph 6652: bhs-25thiaz-gly-betaimid 6653: bim-24thiaz -ala-betadcph 6654: tolhs-25oxaz-gly-zdap 6655: bhs-ithiadiaz-gly-betacbph 6656: tolhs-nme35pyr-gly-betal3bendi 6657: 2py-thiadiaz-bala-betapy
10 6658: dhim-24oxaz-gly-psdap 6659: bhs-nme35pyr-bala-psdap 6660: tolhs-oxadiaz-bala-psdapee 6661: gua-25thiaz-gly-betadmoph 6662 : bhs-me24thioph-ala-betadcph10 6658: dhim-24oxaz-gly-psdap 6659: bhs-nme35pyr-bala-psdap 6660: tolhs-oxadiaz-bala-psdapee 6661: gua-25thiaz-gly-betadmoph 6662: bhs-me24thioph-ala-betadcph
15 6663: bhs-25methiaz-gly-betapbiph 6664: bhs-25oxaz-bala-betadcphch 6665 : ibhs-ithiadiaz-bala-betadmph 6666: bim-23thioph-gly-zdap 6667: phhs-24thiaz-bala-betahb15 6663: bhs-25methiaz-gly-betapbiph 6664: bhs-25oxaz-bala-betadcphch 6665: ibhs-ithiadiaz-bala-betadmph 6666: bim-23thioph-gly-zdap 6667: phhs-24thiaz-bala-betahb
20 6668: tolhs-25methiaz-gly-betapy 6669: bhs-24thioph-met-betadcph 6670 : tolhs-24thioph-bala-betapych 6671: 2py-25thioph-leu-betapy 6672: ibhs-25oxaz-bala-asppha 6673: phhs-me24oxaz-bala-zdap20 6668: tolhs-25methiaz-gly-betapy 6669: bhs-24thioph-met-betadcph 6670: tolhs-24thioph-bala-betapych 6671: 2py-25thioph-leu-betapy 6672: ibhs-25oxaz-bala-asppha 6673: phhs- me24oxaz-bala-zdap
25 6674 : ibhs-25oxaz-bala-betabnaphth 6675: tolhs-24thioph-gly-betapbiph 6676: bhs-ithiadiaz-leu-betapy 6677: bhs-25oxaz-bala-zdap 6678 : phhs-25methiaz-gly-betahcbph25 6674: ibhs-25oxaz-bala-betabnaphth 6675: tolhs-24thioph-gly-betapbiph 6676: bhs-ithiadiaz-leu-betapy 6677: bhs-25oxaz-bala-zdap 6678: phhs-25methiaz-gly-betahcbph
30 6679: tolhs-24thiaz-bala-betahmph 6680: tolhs-nme35pyr-gly-betabpy 6681 : ibhs-25methiaz-gly-betaphethio 6682: tolhs-oxadiaz-bala-betahc 6683: phhs-25oxaz-bala-zdaptb30 6679: tolhs-24thiaz-bala-betahmph 6680: tolhs-nme35pyr-gly-betabpy 6681: ibhs-25methiaz-gly-betaphethio 6682: tolhs-oxadiaz-bala-betahc 6683: phhs-25oxaz-bala-zdaptb
35 6684 : ibhs-nme35pyr-bala-betabnaphth 6685: ibhs-25methiaz-gly-aspbzla 6686 : tolhs-24thiaz-bala-betafluo 6687: bhs-ithiadiaz-nmgly-betacph 6688: tolhs-25oxaz-bala-betaipro 6689: bim-25thioph-leu-betapy35 6684: ibhs-nme35pyr-bala-betabnaphth 6685: ibhs-25methiaz-gly-aspbzla 6686: tolhs-24thiaz-bala-betafluo 6687: bhs-ithiadiaz-nmgly-betacph 6688: tolhs-25oxaz-bala-betaipro 6689: 25thioph-leu-betapy
40 6690 : ibhs-oxadiaz-bala-betathiobe 6691: gua-24thiaz-gly-betathiome 6692: bhs-25thioph-ala-betadcph 6693: 2py-24oxaz-ala-betapy 6694 : phhs-25methiaz-bala-betahcbph40 6690: ibhs-oxadiaz-bala-betathiobe 6691: gua-24thiaz-gly-betathiome 6692: bhs-25thioph-ala-betadcph 6693: 2py-24oxaz-ala-betapy 6694: phhs-25methiaz-bala-betahcbph
45 6695: ibhs-25thiaz-bala-betathioph 6696: ibhs-25oxaz-bala-betapytb 6697: phhs-25thiaz-gly-suabu 6698: phhs-me25thioph-bala-zdap45 6695: ibhs-25thiaz-bala-betathioph 6696: ibhs-25oxaz-bala-betapytb 6697: phhs-25thiaz-gly-suabu 6698: phhs-me25thioph-bala-zdap
6699: phhs-oxadiaz-gly-betahmo6699: phhs-oxadiaz-gly-betahmo
6700: bhs-25thiaz-gly-betabpy6700: bhs-25thiaz-gly-betabpy
6701: phhs-24thiaz-bala-betainyl 5 6702: phhs-24thiaz-bala-betaph6701: phhs-24thiaz-bala-betaph. 5 6702: phhs-24thiaz-bala-betaph
6703 : bhs-25methiaz-nmgly-betainyl6703: bhs-25methiaz-nmgly-betainyl
6704: bhs-nme35pyr-gly-betabpy6704: bhs-nme35pyr-gly-betabpy
6705: bhs-25methiaz-bala-betadtrif6705: bras-25methiaz-bala-betadtrif
6706: phhs-24thiaz-bala-betafluo6706: phhs-24thiaz-bala-betafluo
6707: 2py-25thiaz-bala-zdap6707: 2py-25thiaz-bala-zdap
10 6708: 2py-25oxaz-bala-asppha10 6708: 2py-25oxaz-bala-asppha
6709: tolhs-25methiaz-bala-betafu26709: tolhs-25methiaz-bala-betafu2
6710: bhs-25thiaz-bala-beta34dcph6710: bhs-25thiaz-bala-beta34dcph
6711: 2py-25oxaz-ala-betadcph6711: 2py-25oxaz-ala-betadcph
6712: bhs-25methiaz-bala-zdap 15 6713: phhs-oxadiaz-gly-betamethi6712: bhs-25methiaz-bala-zdap 15 6713: phhs-oxadiaz-gly-betamethi
6714: phhs-ithiadiaz-bala-betamesu6714: phhs-ithiadiaz-bala-betamesu
6715: bhs-24thiaz-bala-betarnethioph6715: bhs-24thiaz-bala-betarnethioph
6716: bhs-25oxaz-gly-betapym6716: bhs-25oxaz-gly-betapym
6717: bhs-ithiadiaz-ala-betainyl 20 6718: phhs-24thioph-gly-betabmph6717: bhs-ithiadiaz-ala-betainyl 20 6718: phhs-24thioph-gly-betabmph
6719: ibhs-25methiaz-gly-betadmph6719: ibhs-25methiaz-gly-betadmph
6720: ibhs-24thiaz-bala-betahmo6720: ibhs-24thiaz-bala-betahmo
6721 : tolhs-24thiaz-gly-beta34dcph6721: tolhs-24thiaz-gly-beta34dcph
6722 : phhs-25methiaz-gly-betaphethioa6722: phhs-25methiaz-gly-betaphethioa
6723: 2py-me25oxaz-leu-betaph6723: 2py-me25oxaz-leu-betaph
25 6724 : phhs-ithiadiaz-bala-betathioph25 6724: phhs-ithiadiaz-bala-betathioph
6725: bhs-me25thiaz-leu-betadcph6725: bhs-me25thiaz-leu-betadcph
6726: bhs-25oxaz-bala-betaol6726: bhs-25oxaz-bala-betaol
6727 : bhs-24thiaz-nmgly-betaanaphth6727: bhs-24thiaz-nmgly-betaanaphth
6728: ibhs-24thioph-bala-betamethioph 30 6729: phhs-25methiaz-bala-betamethi6728: ibhs-24thioph-bala-betamethioph 30 6729: phhs-25methiaz-bala-betamethi
6730: ibhs-nme35pyr-gly-zdapee6730: ibhs-nme35pyr-gly-zdapee
6731 : bhs-24thioph-bala-betal3bendi6731: bhs-24thioph-bala-betal3bendi
6732: ibhs-25oxaz-bala-psdapch6732: ibhs-25oxaz-bala-psdapch
6733 : ibhs-ithiadiaz-gly-betaoxope 35 6734: tolhs-25thiaz-gly-betaol6733: ibhs-ithiadiaz-gly-betaoxope 35 6734: tolhs-25thiaz-gly-betaol
6735: tolhs-nme35pyr-gly-betadtrif6735: tolhs-nme35pyr-gly-betadtrif
6736: bhs-26py-ala-betadcph6736: bhs-26py-ala-betadcph
6737 : tolhs-25thiaz-gly-betadcphtb6737: tolhs-25thiaz-gly-betadcphtb
6738: impy-25methiaz-gly-betabediox6738: impy-25methiaz-gly-betabediox
6739: bhs-25thioph-ala-betapy6739: bhs-25thioph-ala-betapy
40 6740: phhs-25thiaz-gly-betadito40 6740: phhs-25thiaz-gly-betadito
6741 : phhs-oxadiaz-gly-beta34dcph6741: phhs-oxadiaz-gly-beta34dcph
6742: bim-25oxaz-gly-betabpy6742: bim-25oxaz-gly-betabpy
6743 : ibhs-25methiaz-bala-betadcph6743: ibhs-25methiaz-bala-betadcph
6744 : tolhs-25methiaz-bala-ibsdap 45 6745: phhs-oxadiaz-gly-betaftrif6744: tolhs-25methiaz-bala-ibsdap 45 6745: phhs-oxadiaz-gly-betaftrif
6746 : tolhs-oxadiaz-gly-betaoxaz6746: tolhs-oxadiaz-gly-betaoxaz
6747: 2py-thiadiaz-leu-zdap 6748: tolhs-me24thioph-leu-zdap6747: 2py-thiadiaz-leu-zdap 6748: tolhs-me24thioph-leu-zdap
674 : ibhs-oxadiaz-bala-betaoxope674: ibhs-oxadiaz-bala-betaoxope
6750 : bhs-ithiadiaz-gly-betaanaphth6750: bhs-ithiadiaz-gly-betaanaphth
6751: thazep-24thiaz-gly-betainyl 5 6752: tolhs-ithiadiaz-gly-betaipr6751: thazep-24thiaz-gly-betainyl 5 6752: tolhs-ithiadiaz-gly-betaipr
6753: bhs-35thioph-ala-psdap6753: bhs-35thioph-ala-psdap
6754: bhs-24thioph-bala-betapytb6754: bhs-24thioph-bala-betapytb
6755: bhs-me25thiaz-ala-betapy6755: bhs-me25thiaz-ala-betapy
6756: bhs-25oxaz-gly-betaipro6756: bhs-25oxaz-gly-betaipro
6757 : ibhs-25methiaz-bala-betahbcph6757: ibhs-25methiaz-bala-betahbcph
10 6758: bim-52thiaz-gly-betainyl10 6758: bim-52thiaz-gly-betainyl
6759: ibhs-24thioph-bala-betafph6759: ibhs-24thioph-bala-betafph
6760: 2py-25thioph-leu-zdap6760: 2py-25thioph-leu-zdap
6761: ibhs-25oxaz-bala-betaet6761: ibhs-25oxaz-bala-betaet
6762: bhs-me25thiaz-leu-betapy 15 6763: ibhs-25oxaz-gly-betabediox6762: bhs-me25thiaz-leu-betapy 15 6763: ibhs-25oxaz-gly-betabediox
6764: ibhs-nme35pyr-bala-betabpy6764: ibhs-nme35pyr-bala-betabpy
6765: phhs-24thioph-bala-betafph6765: phhs-24thioph-bala-betafph
6766: tolhs-25methiaz-gly-betah35dc6766: tolhs-25methiaz-gly-betah35dc
6767: tolhs-25oxaz-bala-aspibua 20 6768: 2py-oxadiaz-gly-zdap6767: tolhs-25oxaz-bala-aspibua 20 6768: 2py-oxadiaz-gly-zdap
6769: bhs-ithiadiaz-leu-psdap6769: bhs-ithiadiaz-leu-psdap
6770: 2py-24oxaz-gly-psdap6770: 2py-24oxaz-gly-psdap
6771: bhs-46pym-gly-betameph6771: bhs-46pym-gly-betameph
6772 : tolhs-ithiadiaz-bala-zdapch6772: tolhs-ithiadiaz-bala-zdapch
6773: ibhs-25oxaz-gly-betathiome6773: ibhs-25oxaz-gly-betathiome
25 6774: bhs-25oxaz-nmgly-betadmoph25 6774: bhs-25oxaz-nmgly-betadmoph
6775: tolhs-25oxaz-bala-betahbcph6775: tolhs-25oxaz-bala-betahbcph
6776 : ibhs-25oxaz-bala-betaphethio6776: ibhs-25oxaz-bala-betaphethio
6777: phhs-nme35pyr-bala-betadhbfu6777: phhs-nme35pyr-bala-betadhbfu
6778: bhs-me24thioph-ala-zdap 30 6779: bhs-triaz-leu-psdap6778: bhs-me24thioph-ala-zdap 30 6779: bhs-triaz-leu-psdap
6780: ibhs-24thioph-bala-aspibua6780: ibhs-24thioph-bala-aspibua
6781: bhs-24py-gly-betapy6781: bhs-24py-gly-betapy
6782: gua-25thiaz-gly-beta4bph6782: gua-25thiaz-gly-beta4bph
6783 : ibhs-oxadiaz-bala-betabdimo 35 6784: gua-24thiaz-gly-betambiph6783: ibhs-oxadiaz-bala-betabdimo 35 6784: gua-24thiaz-gly-betambiph
6785: bhs-nme35pyr-ala-beta23meoph6785: bhs-nme35pyr-ala-beta23meoph
6786 : bhs-24thioph-bala-betatbuph6786: bhs-24thioph-bala-betatbuph
6787: bhs-nme35pyr-bala-zdap6787: bhs-nme35pyr-bala-zdap
6788 : ibhs-24thioph-bala-betafphe6788: ibhs-24thioph-bala-betafphe
6789: phhs-24thiaz-bala-aspbzla6789: phhs-24thiaz-bala-aspbzla
40 6790: ibhs-ithiadiaz-gly-aspbzla40 6790: ibhs-ithiadiaz-gly-aspbzla
6791: bhs-24thiaz-bala-betaol6791: bhs-24thiaz-bala-betaol
6792 : bhs-25methiaz-gly-betadtrif6792: bhs-25methiaz-gly-betadtrif
6793 : ibhs-25methiaz-bala-betaanaphth6793: ibhs-25methiaz-bala-betaanaphth
6794 : tolhs-25oxaz-gly-betamethi 45 6795: phhs-oxadiaz-bala-betahb6794: tolhs-25oxaz-gly-betamethi 45 6795: phhs-oxadiaz-bala-betahb
6796: 2py-me25thiaz-bala-zdap6796: 2py-me25thiaz-bala-zdap
6797: bhs-24thiaz-gly-betainyl 6798: impy-25thiaz-bala-busu2be6797: bhs-24thiaz-gly-betainyl 6798: impy-25thiaz-bala-busu2be
6799: bhs-24thioph-gly-betadbph6799: bhs-24thioph-gly-betadbph
6800: ibhs-oxadiaz-gly-aspibua6800: ibhs-oxadiaz-gly-aspibua
6801: 2py-25fur-leu-zdap 5 6802: ibhs-25thiaz-gly-betafbph6801: 2py-25fur-leu-zdap 5 6802: ibhs-25thiaz-gly-betafbph
6803 : tolhs-ithiadiaz-bala-betabediox6803: tolhs-ithiadiaz-bala-betabediox
6804: impy-24thioph-bala-betafu36804: impy-24thioph-bala-betafu3
6805: phhs-25methiaz-gly-beta35dbph6805: phhs-25methiaz-gly-beta35dbph
6806 : tolhs-me24thioph-bala-beta34meoph6806: tolhs-me24thioph-bala-beta34meoph
6807: bhs-oxadiaz-bala-betafphe6807: bras-oxadiaz-bala-betafphe
1010
6808: tolhs-oxadiaz-bala-betafu26808: tolhs-oxadiaz-bala-betafu2
6809: cima-25thiaz-gly-betainyl6809: cima-25thiaz-gly-betainyl
6810: bhs-25oxaz-bala-betahph6810: bras-25oxaz-bala-betahph
6811: ibhs-25oxaz-bala-betatos6811: ibhs-25oxaz-bala-betatos
6812: ibhs-25thiaz-bala-betacbph 15 6813 : gua-42pym-gly-betaol6812: ibhs-25thiaz-bala-betacbph 15 6813: gua-42pym-gly-betaol
6814: tolhs-ithiadiaz-bala-psdap6814: tolhs-ithiadiaz-bala-psdap
6815: 2py-26py-gly-betainyl6815: 2py-26py-gly-betainyl
6816: bhs-24thioph-gly-betadhbfu6816: bhs-24thioph-gly-betadhbfu
6817 : tolhs-ithiadiaz-bala-betabph 20 6818: tolhs-24thioph-bala-betaheph6817: tolhs-ithiadiaz-bala-betabph 20 6818: tolhs-24thioph-bala-betaheph
6819 : phhs-25thiaz-gly-betabnaphth6819: phhs-25thiaz-gly-betabnaphth
6820: tolhs-25thiaz-bala-betathiobe6820: tolhs-25thiaz-bala-betathiobe
6821: bhs-oxadiaz-ala-beta34dcph6821: bhs-oxadiaz-ala-beta34dcph
6822: phhs-me24oxaz-leu-betaph6822: phhs-me24oxaz-leu-betaph
6823: bhs-24thiaz-nmgly-betadito6823: bhs-24thiaz-nmgly-betadito
25 6824: phhs-oxadiaz-gly-betahni25 6824: phhs-oxadiaz-gly-betahni
6825: 2py-25oxaz-bala-betamesu6825: 2py-25oxaz-bala-betamesu
6826 : ibhs-nme35pyr-bala-betathiobe6826: ibhs-nme35pyr-bala-betathiobe
6827: bhs-24thioph-gly-betaheph6827: bhs-24thioph-gly-betaheph
6828: phhs-24thiaz-gly-zdapee 30 6829: ibhs-nme35pyr-gly-betadcphch6828: phhs-24thiaz-gly-zdapee 30 6829: ibhs-nme35pyr-gly-betadcphch
6830: tolhs-24thiaz-gly-betatos6830: tolhs-24thiaz-gly-betatos
6831: tolhs-ithiadiaz-bala-betahmo6831: tolhs-ithiadiaz-bala-betahmo
6832: bhs-me24thiaz-gly-betameph6832: bhs-me24thiaz-gly-betameph
6833: a-him-rr.e25thiaz-ala-betarr.eph 35 6834: ibhs-24thiaz-bala-betampy6833: a-him-rr.e25thiaz-ala-betarr.eph 35 6834: ibhs-24thiaz-bala-betampy
6835: ibhs-25oxaz-bala-psdaptb6835: ibhs-25oxaz-bala-psdaptb
6836: tolhs-25thiaz-bala-betampy6836: tolhs-25thiaz-bala-betampy
6837: ibhs-nme35pyr-gly-betarrrpy6837: ibhs-nme35pyr-gly-betarrrpy
6838: tolhs-me25thiaz-gly-zdap6838: tolhs-me25thiaz-gly-zdap
6839: tolhs-25thiaz-bala-betaftrif6839: tolhs-25thiaz-bala-betaftrif
40 6840: ibhs-24thiaz-gly-betafbph40 6840: ibhs-24thiaz-gly-betafbph
6841: bhs-oxadiaz-ala-betadmph6841: bhs-oxadiaz-ala-betadmph
6842 : tolhs-oxadiaz-bala-betadito6842: tolhs-oxadiaz-bala-betadito
6843: tolhs-25thiaz-bala-betamesu6843: tolhs-25thiaz-bala-betamesu
6844 : tolhs-25oxaz-gly-betadcphee 45 6845: gua-25thiaz-gly-beta35dbph6844: tolhs-25oxaz-gly-betadcphee 45 6845: gua-25thiaz-gly-beta35dbph
6846 : tolhs-nme35pyr-gly-betaphethio6846: tolhs-nme35pyr-gly-betaphethio
6847: gua-24oxaz-gly-beta34dcph 6848: 2py-24thiaz-ala-zdap 6849: tolhs-oxadiaz-gly-betafphe 6850 : tolhs-25oxaz-gly-beta23meoph 6851 : ibhs-24thiaz-bala-beta23meoph 6852: phhs-nme35pyr-gly-betahc 6853 : gua-24oxaz-gly-betadmph 6854: bhs-25fur-gly-psdap 6855: bhs-24thiaz-gly-betadbph 6856: ibhs-25thiaz-gly-betabph 6857: 2py-triaz-ala-psdap6847: gua-24oxaz-gly-beta34dcph 6848: 2py-24thiaz-ala-zdap 6849: tolhs-oxadiaz-gly-betafphe 6850: tolhs-25oxaz-gly-beta23meoph 6851: ibhs-24thiaz-bala-beta23meoph 6852: phhs-nme35pyr-gly-betahc 6853: gua-24ox -gly-betadmph 6854: bhs-25fur-gly-psdap 6855: bhs-24thiaz-gly-betadbph 6856: ibhs-25thiaz-gly-betabph 6857: 2py-triaz-ala-psdap
10 6858: tolhs-ithiadiaz-bala-csdap 6859 : tolhs-ithiadiaz-gly-betadito 6860: tolhs-24thiaz-gly-betapyr 6861: bhs-ithiadiaz-gly-betafluo 6862: tolhs-24thioph-gly-betafu210 6858: tolhs-ithiadiaz-bala-csdap 6859: tolhs-ithiadiaz-gly-betadito 6860: tolhs-24thiaz-gly-betapyr 6861: bhs-ithiadiaz-gly-betafluo 6862: tolhs-24thioph-gly-betafu2
15 6863: ibhs-24thioph-gly-betathioph 6864: 2py-53pyrazo-bala-betadcph 6865 : tolhs-oxadiaz-bala-betabenfu 6866: tolhs-25thiaz-bala-betahmo 6867: ibhs-oxadiaz-gly-betahb15 6863: ibhs-24thioph-gly-betathioph 6864: 2py-53pyrazo-bala-betadcph 6865: tolhs-oxadiaz-bala-betabenfu 6866: tolhs-25thiaz-bala-betahmo 6867: ibhs-oxadiaz-gly-betahb
20 6868: bhs-25thiaz-ala-betameph 6869 : phhs-ithiadiaz-gly-betathiome 6870: phhs-oxadiaz-gly-betadbph 6871: tolhs-25oxaz-gly-betaoxope 6872 : bhs-oxadiaz-bala-betadbph 6873 : bhs-ithiadiaz-bala-betadcphee20 6868: bhs-25thiaz-ala-betameph 6869: phhs-ithiadiaz-gly-betathiome 6870: phhs-oxadiaz-gly-betadbph 6871: tolhs-25oxaz-gly-betaoxope 6872: bhs-oxadiaz-bala-betadbph 6873: bhs- ithiadiaz-bala-betadcphee
25 6874: bhs-me24oxaz-gly-betadcph 6875: tolhs-25thiaz-gly-betaphethioa 6876: dhim-26py-ala-betameph 6877: tolhs-oxadiaz-gly-psdap 6878: tolhs-oxadiaz-bala-betahcbph25 6874: bhs-me24oxaz-gly-betadcph 6875: tolhs-25thiaz-gly-betaphethioa 6876: dhim-26py-ala-betameph 6877: tolhs-oxadiaz-gly-psdap 6878: tolhs-oxadiaz-bala-betahcbph
30 6879: bim-24thiaz-bala-aspbzla30 6879: bim-24thiaz-bala-aspbzla
6880 : phhs-24thioph-gly-beta34dcph 6881: bim-42oxaz-leu-zdap 6882 : phhs-25oxaz-bala-betathiobe 6883 : tolhs-24thiaz-bala-betathio36880: phhs-24thioph-gly-beta34dcph 6881: bim-42oxaz-leu-zdap 6882: phhs-25oxaz-bala-betathiobe 6883: tolhs-24thiaz-bala-betathio3
35 6884: 2py-35thioph-bala-zdap 6885: bim-25fur-bala-zdap 6886: bim-me25thioph-leu-psdap 6887 : ibhs-25thiaz-gly-betafu2 6888: bhs-24thiaz-gly-betaamibe 6889: 2pmhs-24thiaz-gly-betameph35 6884: 2py-35thioph-bala-zdap 6885: bim-25fur-bala-zdap 6886: bim-me25thioph-leu-psdap 6887: ibhs-25thiaz-gly-betafu2 6888: bhs-24thiaz-gly-betaamibe 6889: 2 pmhs- 24thiaz-gly-betameph
40 6890: ibhs-24thioph-gly-psdapee 6891 : phhs-25methiaz-gly-psdapch 6892: ibhs-24thiaz-gly-suabu 6893: bhs-25thiaz-ala-betapy 6894: dhim-52thiaz-ala-psdap40 6890: ibhs-24thioph-gly-psdapee 6891: phhs-25methiaz-gly-psdapch 6892: ibhs-24thiaz-gly-suabu 6893: bhs-25thiaz-ala-betapy 6894: dhim-52thiaz-ala-psdap
45 6895: tθlhs-25thiaz-gly-zdaptb 6896: ibhs-24thiaz-gly-aspibua 6897 : 2pmhs-42nmeim-bala-beta23meoph 6898: 2py-52thiaz-gly-betapy45 6895: tθlhs-25thiaz-gly-zdaptb 6896: ibhs-24thiaz-gly-aspibua 6897: 2 pmhs-42nmeim-bala-beta23meoph 6898: 2py-52thiaz-gly-betapy
6899 : bhs-ithiadiaz-gly-betathiome6899: bhs-ithiadiaz-gly-betathiome
6900 : bhs-ithiadiaz-bala-betabnaphth6900: bhs-ithiadiaz-bala-betabnaphth
6901: 2py-24oxaz-leu-zdap6901: 2py-24oxaz-leu-zdap
6902 : tolhs-24thioph-bala-betaphethio6902: tolhs-24thioph-bala-betaphethio
6903: bhs-35fur-gly-zdap6903: bhs-35fur-gly-zdap
6904: hts-25thiaz-gly-betapy6904: hts-25thiaz-gly-betapy
6905: 2py-oxadiaz-bala-aspibua6905: 2py-oxadiaz-bala-aspibua
6906 : tolhs-nme35pyr-gly-betahdcph6906: tolhs-nme35pyr-gly-betahdcph
6907 : ibhs-ithiadiaz-bala-psdaptb6907: ibhs-ithiadiaz-bala-psdaptb
10 6908: ibhs-25methiaz-bala-betacbph10 6908: ibhs-25methiaz-bala-betacbph
6909: 2py-25oxaz-bala-busu2be6909: 2py-25oxaz-bala-busu2be
6910: bim-me25thiaz-leu-betaph6910: bim-me25thiaz-leu-betaph
6911 : phhs-25thiaz-bala-betaphethioa6911: phhs-25thiaz-bala-betaphethioa
6912 : ibhs-ithiadiaz-bala-betafluo6912: ibhs-ithiadiaz-bala-betafluo
15 6913: gua-25thioph-gly-betadcph15 6913: gua-25thioph-gly-betadcph
6914 : bhs-25thiaz-bala-betaomebendi 6915: phhs-25methiaz-bala-betaet 6916: 2pmhs-42nmeim-bala-betahdbph 6917: bhs-35thioph-gly-zdap6914: bhs-25thiaz-bala-betaomebendi 6915: phhs-25methiaz-bala-betaet 6916: 2 pmhs-42nmeim-bala-betahdbph 6917: bhs-35thioph-gly-zdap
20 6918: ibhs-oxadiaz-bala-ibsdap20 6918: ibhs-oxadiaz-bala-ibsdap
6919 : tolhs-24thiaz-gly-betaanaphth 6920: 2py-me24oxaz-leu-betadcph 6921: phhs-25methiaz-bala-psdapee 6922 : pahs-42nmeim-bala-betadcph 6923: ibhs-oxadiaz-bala-betaol6919: tolhs-24thiaz-gly-betaanaphth 6920: 2py-me24oxaz-leu-betadcph 6921: phhs-25methiaz-bala-psdapee 6922: pahs-42nmeim-bala-betadcph 6923: ibhs-oxadiaz-bala-betaol
25 6924: ibhs-25thiaz-gly-betapych 6925: bhs-42nmeim-leu-psdap 6926: tolhs-nme35pyr-gly-betadmoph 6927: phhs-24thioph-gly-ibsdap 6928: tolhs-me25thioph-gly-psdap25 6924: ibhs-25thiaz-gly-betapych 6925: bhs-42nmeim-leu-psdap 6926: tolhs-nme35pyr-gly-betadmoph 6927: phhs-24thioph-gly-ibsdap 6928: tolhs-me25thioph-gly-psdap
30 6929: phhs-25oxaz-gly-betaoxope 6930: bhs-oxadiaz-gly-aspaba 6931 : tolhs-25thiaz-bala-betafluo 6932: tolhs-25methiaz-gly-betahb 6933 : tolhs-ithiadiaz-gly-psdapee30 6929: phhs-25oxaz-gly-betaoxope 6930: bhs-oxadiaz-gly-aspaba 6931: tolhs-25thiaz-bala-betafluo 6932: tolhs-25methiaz-gly-betahb 6933: tolhs-ithiadiaz-gly-psdapee
35 6934: 2py-42nmeim-gly-betahc 6935: tolhs-25thiaz-gly-betaphethio 6936 : bhs-ithiadiaz-bala-betamethi 6937: tolhs-25methiaz-gly-betabph 6938: bhs-24thioph-gly-betaanaphth 6939 : phhs-25methiaz-gly-beta34meoph35 6934: 2py-42nmeim-gly-betahc 6935: tolhs-25thiaz-gly-betaphethio 6936: bhs-ithiadiaz-bala-betamethi 6937: tolhs-25methiaz-gly-betabph 6938: bhs-24thioph-gly-betaanaphth 6939: phhs- 25methiaz-gly-beta34meoph
40 6940 : tolhs-25methiaz-gly-betadmoph 6941: bhs-24thiaz-gly-betadmph 6942: 2py-24thioph-gly-beta35dbph 6943: ibhs-25oxaz-gly-betabmph 6944 : bhs-ithiadiaz-bala-beta34meoph40 6940: tolhs-25methiaz-gly-betadmoph 6941: bhs-24thiaz-gly-betadmph 6942: 2py-24thioph-gly-beta35dbph 6943: ibhs-25oxaz-gly-betabmph 6944: bhs-ithiadiaz-bala-beta34meoph
45 6945: bim-42oxaz-ala-betadcph45 6945: bim-42oxaz-ala-betadcph
6946 : tolhs-25methiaz-gly-betathiome 6947: ibhs-nme35pyr-bala-csdap 6948: bhs-ithiadiaz-ala-betamesu6946: tolhs-25methiaz-gly-betathiome 6947: ibhs-nme35pyr-bala-csdap 6948: bhs-ithiadiaz-ala-betamesu
6949: thpym-26py-gly-betahdcph6949: thpym-26py-gly-betahdcph
6950: 2py-ithiadiaz-bala-betapy6950: 2py-ithiadiaz-bala-betapy
6951: tolhs-oxadiaz-gly-asppha 5 6952: bhs-nme35pyr-nmgly-betaanaphth6951: tolhs-oxadiaz-gly-asppha 5 6952: bhs-nme35pyr-nmgly-betaanaphth
6953: phhs-25thiaz-bala-betahmo6953: phhs-25thiaz-bala-betahmo
6954: bhs-25oxaz-gly-betadhbfu6954: bhs-25oxaz-gly-betadhbfu
6955: bhs-24thiaz-nmgly-betacthioph6955: bhs-24thiaz-nmgly-betacthioph
6956: tolhs-25thiaz-bala-ibsdap6956: tolhs-25thiaz-bala-ibsdap
6957 : tolhs-nme35pyr-bala-beta23meoph6957: tolhs-nme35pyr-bala-beta23meoph
10 6958: bim-24thioph-gly-betadcph10 6958: bim-24thioph-gly-betadcph
6959: tolhs-24thioph-bala-betahc6959: tolhs-24thioph-bala-betahc
6960: bhs-25thiaz-bala-betahcbph6960: bras-25thiaz-bala-betahcbph
6961 : tolhs-24thiaz-bala-betadhbfu6961: tolhs-24thiaz-bala-betadhbfu
6962 : ibhs-25methiaz-bala-betadtrif 15 6963: phhs-25methiaz-bala-beta23meoph6962: ibhs-25methiaz-bala-betadtrif 15 6963: phhs-25methiaz-bala-beta23meoph
6964: phhs-nme35pyr-bala-betampy6964: phhs-nme35pyr-bala-betampy
6965: bhs-25thiaz-gly-betahcbph6965: bhs-25thiaz-gly-betahcbph
6966: bhs-ithiadiaz-ala-zdap6966: bhs-ithiadiaz-ala-zdap
6967 : tolhs-25thiaz-bala-betaimid 20 6968: phhs-25thiaz-gly-betaamibe6967: tolhs-25thiaz-bala-betaimide 20 6968: phhs-25thiaz-gly-betaamibe
6969: bim-ithiadiaz-ala-betapy6969: bim-ithiadiaz-ala-betapy
6970: bhs-42pym-ala-betainyl6970: bhs-42pym-ala-betainyl
6971: tolhs-25thiaz-bala-betafu26971: tolhs-25thiaz-bala-betafu2
6972 : 2pmhs-24thioph-gly-betathiome6972: 2 pmhs-24thioph-gly-betathiome
6973 : imhs-24thiaz-gly-zdap6973: imhs-24thiaz-gly-zdap
25 6974: dhim-52thiaz-gly-betapy 6975: tolhs-24thioph-bala-betamesu 6976: phhs-ithiadiaz-bala-betahmo 6977: gua-25thiaz-gly-betaibph 6978: ibhs-24thiaz-bala-betadito25 6974: dhim-52thiaz-gly-betapy 6975: tolhs-24thioph-bala-betamesu 6976: phhs-ithiadiaz-bala-betahmo 6977: gua-25thiaz-gly-betaibph 6978: ibhs-24thiaz-bala-betadito
30 6979: phhs-nme35pyr-gly-betambiph30 6979: phhs-nme35pyr-gly-betambiph
6980: dhpyrr-25thioph-gly-betapy6980: dhpyrr-25thioph-gly-betapy
6981: bhs-25thiaz-nmgly-betal3bendi6981: bhs-25thiaz-nmgly-betal3bendi
6982: bhs-42nmeim-gly-betaoxope6982: bhs-42nmeim-gly-betaoxope
6983: bim-42pym-ala-betadcph 35 6984: tolhs-me24thioph-leu-psdap6983: bim-42pym-ala-betadcph 35 6984: tolhs-me24thioph-leu-psdap
6985: 2py-42nmeim-leu-betapy6985: 2py-42nmeim-leu-betapy
6986: phhs-oxadiaz-bala-betamesu6986: phhs-oxadiaz-bala-betamesu
6987: tolhs-24thioph-bala-aspaba6987: tolhs-24thioph-bala-aspaba
6988: dhim-26py-ala-zdap6988: dhim-26py-ala-zdap
6989: bhs-oxadiaz-bala-betampy6989: bras-oxadiaz-bala-betampy
40 6990 : ibhs-25thiaz-bala-betamethioph40 6990: ibhs-25thiaz-bala-betamethioph
6991: 2py-42pym-gly-betameph6991: 2py-42pym-gly-betameph
6992 : tolhs-ithiadiaz-bala-betadmph6992: tolhs-ithiadiaz-bala-betadmph
6993: gua-24thiaz-gly-betahmo6993: gua-24thiaz-gly-betahmo
6994: bhs-ithiadiaz-bala-betapym 45 6995: bhs-24thioph-ala-betacthioph6994: bhs-ithiadiaz-bala-betapym 45 6995: bhs-24thioph-ala-betacthioph
6996: bhs-24thiaz-bala-betahph6996: bras-24thiaz-bala-betahph
6997: phhs-ithiadiaz-gly-betadito 6998: phhs-me24oxaz-ala-betapy 6999: bhs-52thiaz-ala-betapy6997: phhs-ithiadiaz-gly-betadito 6998: phhs-me24oxaz-ala-betapy 6999: bhs-52thiaz-ala-betapy
7000: bhs-me25oxaz-ala-zdap 7001: ibhs-25oxaz-bala-betabenfu 5 7002: phhs-24thiaz-bala-beta34dcph7000: bhs-me25oxaz-ala-zdap 7001: ibhs-25oxaz-bala-betabenfu 5 7002: phhs-24thiaz-bala-beta34dcph
7003 : ibhs-24thiaz-bala-betadcphch7003: ibhs-24thiaz-bala-betadcphch
7004: ibhs-25thiaz-gly-betatrif7004: ibhs-25thiaz-gly-betatrif
7005: ibhs-oxadiaz-gly-betahbcph7005: ibhs-oxadiaz-gly-betahbcph
7006: bhs-nme35pyr-bala-betaimid7006: bhs-nme35pyr-bala-betaimid
7007: bhs-oxadiaz-bala-betaamibe7007: bras-oxadiaz-bala-betaamibe
10 7008: phhs-25oxaz-bala-betafu210 7008: phhs-25oxaz-bala-betafu2
7009 : tolhs-24thioph-gly-betahbcph7009: tolhs-24thioph-gly-betahbcph
7010: 2py-25fur-bala-betapy7010: 2py-25fur-bala-betapy
7011: 2py-25oxaz-bala-betainyl7011: 2py-25oxaz-bala-betainyl
7012: tolhs-me25thiaz-leu-betaph 15 7013: bhs-ithiadiaz-bala-betadmph7012: tolhs-me25thiaz-leu-betaph 15 7013: bhs-ithiadiaz-bala-betadmph
7014: bhs-nme35pyr-gly-busu2be7014: bhs-nme35pyr-gly-busu2be
7015: bhs-me24thiaz-gly-betadcph7015: bhs-me24thiaz-gly-betadcph
7016: tolhs-oxadiaz-bala-suabu7016: tolhs-oxadiaz-bala-suabu
7017 : bhs-24thioph-ala-beta34meoph 20 7018: tolhs-24thiaz-bala-betabnaphth7017: bhs-24thioph-ala-beta34meoph 20 7018: tolhs-24thiaz-bala-betabnaphth
7019: ibhs-25methiaz-gly-zdapee7019: ibhs-25methiaz-gly-zdapee
7020 : tolhs-24thiaz-bala-betacbph7020: tolhs-24thiaz-bala-betacbph
7021: bhs-25thiaz-bala-betahni7021: bras-25thiaz-bala-betahni
7022: ibhs-oxadiaz-bala-betaheph7022: ibhs-oxadiaz-bala-betaheph
7023 : phhs-25thiaz-bala-betapbiph7023: phhs-25thiaz-bala-betapbiph
25 7024: ibhs-25oxaz-gly-betafu325 7024: ibhs-25oxaz-gly-betafu3
7025: tolhs-24thioph-bala-betadcph7025: tolhs-24thioph-bala-betadcph
7026 : 2py-me25thiaz-bala-beta34meoph7026: 2py-me25thiaz-bala-beta34meoph
7027 : tolhs-ithiadiaz-gly-betaomebendi7027: tolhs-ithiadiaz-gly-betaomebendi
7028: tolhs-24thiaz-bala-psdapch 30 7029: phhs-nme35pyr-bala-beta23meoph7028: tolhs-24thiaz-bala-psdapch 30 7029: phhs-nme35pyr-bala-beta23meoph
7030 : bhs-24thioph-gly-betadcphch7030: bhs-24thioph-gly-betadcphch
7031: phhs-nme35pyr-gly-betafph7031: phhs-nme35pyr-gly-betafph
7032 : tolhs-24thioph-bala-betadcphtb7032: tolhs-24thioph-bala-betadcphtb
7033: bhs-nme35pyr-bala-betadmph 35 7034: bhs-oxadiaz-gly-betadcphtb7033: bhs-nme35pyr-bala-betadmph 35 7034: bhs-oxadiaz-gly-betadcphtb
7035: phhs-ithiadiaz-gly-betapyr7035: phhs-ithiadiaz-gly-betapyr
7036: dhim-24thiaz-gly-betameph7036: dhim-24thiaz-gly-betameph
7037: bgua-24thiaz-gly-betameph7037: bgua-24thiaz-gly-betameph
7038: bhs-24thiaz-ala-betapy7038: bhs-24thiaz-ala-betapy
7039: tolhs-24thiaz-bala-betaet7039: tolhs-24thiaz-bala-betet
40 7040: ibhs-25thiaz-gly-betadbph40 7040: ibhs-25thiaz-gly-betadbph
7041: 2py-26py-gly-betaanaphth7041: 2py-26py-gly-betaanaphth
7042: bhs-25oxaz-bala-betadhbfu7042: bhs-25oxaz-bala-betadhbfu
7043: phhs-25oxaz-gly-betamethi7043: phhs-25oxaz-gly-betamethi
7044: bim-24im-gly-psdap 45 7045: tolhs-25oxaz-gly-betadhbfu7044: bim-24im-gly-psdap 45 7045: tolhs-25oxaz-gly-betadhbfu
7046: gua-24oxaz-gly-betahb7046: gua-24oxaz-gly-betahb
7047: phhs-oxadiaz-bala-betaph 7048 : ibhs-24thioph-bala-betao ebendi7047: phhs-oxadiaz-bala-betaph 7048: ibhs-24thioph-bala-betao ebendi
7049: bhs-24thiaz-ala-beta3quin7049: bhs-24thiaz-ala-beta3quin
7050 : bhs-25oxaz-bala-beta34meoph7050: bhs-25oxaz-bala-beta34meoph
7051 : ibhs-25methiaz-gly-beta4bph 5 7052: bhs-nme35pyr-bala-betapbiph7051: ibhs-25methiaz-gly-beta4bph 5 7052: bhs-nme35pyr-bala-betapbiph
7053: phhs-25methiaz-bala-psdap7053: phhs-25methiaz-bala-psdap
7054: bhs-25methiaz-bala-betahcbph7054: bras-25methiaz-bala-betahcbph
7055: bhs-oxadiaz-gly-betafu37055: bhs-oxadiaz-gly-betafu3
7056 : phhs-oxadiaz-bala-betaanaphth7056: phhs-oxadiaz-bala-betaanaphth
7057: 2py-42nmeim-gly-zdap7057: 2py-42nmeim-gly-zdap
10 7058: bhs-53pyrazo-leu-betadcph10 7058: bras-53pyrazo-leu-betadcph
7059: ibhs-25oxaz-bala-betahcbph7059: ibhs-25oxaz-bala-betahcbph
7060: gua-24thiaz-gly-betaol7060: gua-24thiaz-gly-betaol
7061: ibhs-nme35pyr-bala-aspaba7061: ibhs-nme35pyr-bala-aspaba
7062: impy-42nmeim-gly-betathioph 15 7063: tolhs-24thioph-bala-betahph7062: impy-42nmeim-gly-betathioph 15 7063: tolhs-24thioph-bala-betahph
7064: bhs-24thiaz-bala-betamesu7064: bras-24thiaz-bala-betamesu
7065: phhs-nme35pyr-gly-betathio37065: phhs-nme35pyr-gly-betathio3
7066: 2py-24thioph-bala-betapy7066: 2py-24thioph-bala-betapy
7067 : phhs-25thiaz-gly-betadcphch 20 7068: phhs-ithiadiaz-gly-betabdimo7067: phhs-25thiaz-gly-betadcphch 20 7068: phhs-ithiadiaz-gly-betabdimo
7069 : bim-me24thioph-ala-betadcph7069: bim-me24thioph-ala-betadcph
7070: phhs-25methiaz-bala-zdaptb7070: phhs-25methiaz-bala-zdaptb
7071: tolhs-25oxaz-gly-betafbph7071: tolhs-25oxaz-gly-betafbph
7072: bgua-25thiaz-gly-betameph7072: bgua-25thiaz-gly-betameph
7073 : thazep-25thioph-gly-betadcph7073: thazep-25thioph-gly-betadcph
25 7074: 2py-me24oxaz-gly-zdap25 7074: 2py-me24oxaz-gly-zdap
7075: tolhs-24thioph-gly-betadtrif7075: tolhs-24thioph-gly-betadtrif
7076 : tolhs-ithiadiaz-gly-betal3bendi7076: tolhs-ithiadiaz-gly-betal3bendi
7077: bhs-me25thioph-bala-psdap7077: bhs-me25thioph-bala-psdap
7078: ibhs-nme35pyr-bala-betampy 30 7079: phhs-25oxaz-gly-betahni7078: ibhs-nme35pyr-bala-betampy 30 7079: phhs-25oxaz-gly-betahni
7080: tolhs-24thioph-gly-betambiph7080: tolhs-24thioph-gly-betambiph
7081: 2py-25thiaz-hphe-psdap7081: 2py-25thiaz-hphe-psdap
7082: tolhs-25oxaz-bala-zdapch7082: tolhs-25oxaz-bala-zdapch
7083 : tolhs-nme35pyr-bala-beta3quin 35 7084: ibhs-25oxaz-bala-betahmph7083: tolhs-nme35pyr-bala-beta3quin 35 7084: ibhs-25oxaz-bala-betahmph
7085: phhs-nme35pyr-gly-betadcphtb7085: phhs-nme35pyr-gly-betadcphtb
7086: bhs-nme35pyr-gly-betadmph7086: bhs-nme35pyr-gly-betadmph
7087: phhs-25methiaz-gly-betadmph7087: phhs-25methiaz-gly-betadmph
7088: ibhs-nme35pyr-gly-beta3quin7088: ibhs-nme35pyr-gly-beta3quin
7089: ibhs-24thiaz-bala-betaibph7089: ibhs-24thiaz-bala-betaibph
40 7090: bhs-25oxaz-bala-busu2be40 7090: bhs-25oxaz-bala-busu2be
7091: dhim-42pym-gly-zdap7091: dhim-42pym-gly-zdap
7092 : tolhs-25methiaz-bala-betatos7092: tolhs-25methiaz-bala-betatos
7093 : phhs-nme35pyr-gly-betal3bendi7093: phhs-nme35pyr-gly-betal3bendi
7094: bhs-24thioph-gly-betabph 45 7095: tolhs-oxadiaz-bala-betaphethioa7094: bhs-24thioph-gly-betabph 45 7095: tolhs-oxadiaz-bala-betaphethioa
7096 : ibhs-nme35pyr-gly-betathiome7096: ibhs-nme35pyr-gly-betathiome
7097: bhs-oxadiaz-bala-betamesu 7098: bhs-oxadiaz-gly-zdapee7097: bras-oxadiaz-bala-betamesu 7098: bhs-oxadiaz-gly-zdapee
7099: phhs-oxadiaz-gly-beta3quin7099: phhs-oxadiaz-gly-beta3quin
7100: ibhs-25methiaz-gly-betaipr7100: ibhs-25methiaz-gly-betaipr
7101 : ibhs-nme35pyr-bala-betaphethioa 5 7102: gua-24oxaz-gly-betaol7101: ibhs-nme35pyr-bala-betaphethioa 5 7102: gua-24oxaz-gly-betaol
7103 : tolhs-24thiaz-bala-betapyee7103: tolhs-24thiaz-bala-betapyee
7104 : bhs-ithiadiaz-nmgly-betacthioph7104: bhs-ithiadiaz-nmgly-betacthioph
7105 : phhs-oxadiaz-gly-betadcphtb7105: phhs-oxadiaz-gly-betadcphtb
7106 : tolhs-ithiadiaz-gly-betabnaphth7106: tolhs-ithiadiaz-gly-betabnaphth
7107: ibhs-25oxaz-bala-betabmph7107: ibhs-25oxaz-bala-betabmph
1010
7108: bim-52thiaz-ala-psdap7108: bim-52thiaz-ala-psdap
7109: tolhs-25methiaz-gly-betamesu7109: tolhs-25methiaz-gly-betamesu
7110: hyd-25oxaz-gly-betapy7110: hyd-25oxaz-gly-betapy
7111: bhs-24thioph-bala-betapyee7111: bhs-24thioph-bala-betapyee
7112: 2py-26py-ala-betameph 15 7113: bim-25methiaz-gly-aspbzla7112: 2py-26py-ala-betameph 15 7113: bim-25methiaz-gly-aspbzla
7114: ibhs-nme35pyr-gly-betadmph7114: ibhs-nme35pyr-gly-betadmph
7115: bim-25thiaz-bala-betadcph7115: bim-25thiaz-bala-betadcph
7116 : tolhs-24thioph-gly-betatrif7116: tolhs-24thioph-gly-betatrif
7117 : phhs-24thiaz-gly-betamethioph 20 7118: tolhs-me24thiaz-ala-betadcph7117: phhs-24thiaz-gly-betamethioph 20 7118: tolhs-me24thiaz-ala-betadcph
7119: phhs-oxadiaz-gly-betadito7119: phhs-oxadiaz-gly-betadito
7120: tolhs-ithiadiaz-gly-beta34meoph7120: tolhs-ithiadiaz-gly-beta34meoph
7121: bhs-ithiadiaz-gly-zdaptb7121: bhs-ithiadiaz-gly-zdaptb
7122 : impy-24thioph-bala-betah35dc7122: impy-24thioph-bala-betah35dc
7123: ibhs-25oxaz-bala-betadbph7123: ibhs-25oxaz-bala-betadbph
25 7124: 2py-25thioph-gly-betameph25 7124: 2py-25thioph-gly-betameph
7125: bim-25methiaz-bala-betahc7125: bim-25methiaz-bala-betahc
7126 : tolhs-me24thioph-gly-betaph7126: tolhs-me24thioph-gly-betaph
7127 : tolhs-oxadiaz-gly-betaftrif7127: tolhs-oxadiaz-gly-betaftrif
7128 : ibhs-oxadiaz-gly-betathiobe 30 7129: tolhs-nme35pyr-gly-beta35dbph7128: ibhs-oxadiaz-gly-betathiobe 30 7129: tolhs-nme35pyr-gly-beta35dbph
7130: ibhs-nme35pyr-bala-ibsdap7130: ibhs-nme35pyr-bala-ibsdap
7131: phhs-25oxaz-gly-betahmph7131: phhs-25oxaz-gly-betahmph
7132: bhs-oxadiaz-ala-betadhbfu7132: bhs-oxadiaz-ala-betadhbfu
7133: impy-25thiaz-bala-betamethi 35 7134: ibhs-nme35pyr-bala-psdapch7133: impy-25thiaz-bala-betamethi 35 7134: ibhs-nme35pyr-bala-psdapch
7135: bhs-me25oxaz-ala-psdap7135: bhs-me25oxaz-ala-psdap
7136: bhs-ithiadiaz-nmgly-betahph7136: bhs-ithiadiaz-nmgly-betahph
7137 : bhs-oxadiaz-ala-betacthioph7137: bhs-oxadiaz-ala-betacthioph
7138: dhim-26py-phe-zdap7138: dhim-26py-phe-zdap
7139: bhs-24thioph-bala-betah35dc7139: bhs-24thioph-bala-betah35dc
40 7140: bhs-oχadiaz-bala-busu2be40 7140: bhs-oχadiaz-bala-busu2be
7141: ibhs-25thiaz-gly-betaol7141: ibhs-25thiaz-gly-betaol
7142: bhs-oxadiaz-bala-betatbuph7142: bras-oxadiaz-bala-betatbuph
7143: ibhs-nme35pyr-bala-betaipro7143: ibhs-nme35pyr-bala-betaipro
7144: bhs-me24thioph-leu-betaph 45 7145: ibhs-24thioph-gly-betampy7144: bhs-me24thioph-leu-betaph 45 7145: ibhs-24thioph-gly-betampy
7146: phhs-oxadiaz-gly-psdap7146: phhs-oxadiaz-gly-psdap
7147 : bhs-nme35pyr-gly-betamethioph 7148: bhs-25methiaz-bala-betathio37147: bhs-nme35pyr-gly-betamethioph 7148: bhs-25methiaz-bala-betathio3
7149 : tolhs-24thiaz-bala-betainyl7149: tolhs-24thiaz-bala-betainyl
7150 : phhs-me25thioph-leu-beta34meoph7150: phhs-me25thioph-leu-beta34meoph
7151: 2py-me25thiaz-leu-psdap 5 7152: bhs-ithiadiaz-bala-aspbzla7151: 2py-me25thiaz-leu-psdap 5 7152: bhs-ithiadiaz-bala-aspbzla
7153: thpy -42nmeim-gly-psdap7153: thpy -42nmeim-gly-psdap
7154: phhs-24thioph-gly-betainyl7154: phhs-24thioph-gly-betainyl
7155: phhs-25methiaz-gly-betambiph7155: phhs-25methiaz-gly-betambiph
7156: ibhs-nme35pyr-gly-suabu7156: ibhs-nme35pyr-gly-suabu
7157: bhs-oxadiaz-gly-betameph7157: bhs-oxadiaz-gly-betameph
10 7158 : impy-24thiaz-gly-beta34meoph10 7158: impy-24thiaz-gly-beta34meoph
7159 : ibhs-nme35pyr-bala-betatbuph7159: ibhs-nme35pyr-bala-betatbuph
7160: ibhs-24thioph-gly-busu2be7160: ibhs-24thioph-gly-busu2be
7161: bhs-24thJoph-gly-betamesu7161: bhs-24thJoph-gly-betamesu
7162: tolhs-ithiadiaz-gly-zdap 15 7163: gua-25thiaz-gly-betameph7162: tolhs-ithiadiaz-gly-zdap 15 7163: gua-25thiaz-gly-betameph
7164 : ibhs-nme35pyr-gly-betacthioph7164: ibhs-nme35pyr-gly-betacthioph
7165: bhs-24im-leu-psdap7165: bhs-24im-leu-psdap
7166: ibhs-24thiaz-bala-betacbph7166: ibhs-24thiaz-bala-betacbph
7167: bhs-oxadiaz-bala-betahni 2o 7168: tolhs-24thiaz-gly-betapyee7167: bhs-oxadiaz-bala-betahni 2o 7168: tolhs-24thiaz-gly-betapyee
7169: ibhs-24thioph-bala-betapyr7169: ibhs-24thioph-bala-betapyr
7170 : phhs-nme35pyr-gly-beta34meoph7170: phhs-nme35pyr-gly-beta34meoph
7171: bhs-24thiaz-ala-betadito7171: bhs-24thiaz-ala-betadito
7172 : bim-42nmeim-bala-betabthioph7172: bim-42nmeim-bala-betabthioph
7173: bhs-24thiaz-bala-betacbph7173: bras-24thiaz-bala-betacbph
25 7174 : ibhs-nme35pyr-bala-betahph25 7174: ibhs-nme35pyr-bala-betahph
7175: phhs-ithiadiaz-gly-betahmph7175: phhs-ithiadiaz-gly-betahmph
7176 : tolhs-ithiadiaz-bala-psdaptb7176: tolhs-ithiadiaz-bala-psdaptb
7177: ibhs-25oxaz-bala-betadmoph7177: ibhs-25oxaz-bala-betadmoph
7178: tolhs-me24oxaz-ala-zdap 30 7179: ibhs-ithiadiaz-bala-betahcbph7178: tolhs-me24oxaz-ala-zdap 30 7179: ibhs-ithiadiaz-bala-betahcbph
7180: ibhs-25methiaz-bala-betathioph7180: ibhs-25methiaz-bala-betathioph
7181 : tolhs-25methiaz-gly-psdaptb7181: tolhs-25methiaz-gly-psdaptb
7182: tolhs-25oxaz-bala-betaph7182: tolhs-25oxaz-bala-betaph
7183: bhs-25thiaz-ala-betadmph 35 7184: bhs-24oxaz-bala-betadcph7183: bras-25thiaz-ala-betadmph 35 7184: bras-24oxaz-bala-betadcph
7185: ibhs-24thioph-bala-psdapee7185: ibhs-24thioph-bala-psdapee
7186: bhs-ithiadiaz-gly-betapyr7186: bhs-ithiadiaz-gly-betapyr
7187: bhs-42nmeim-bala-betadito7187: bras-42nmeim-bala-betadito
7188: bim-24thiaz-bala-asppha7188: bim-24thiaz-bala-asppha
7189 : bhs-24thiaz-gly-beta23meoph7189: bhs-24thiaz-gly-beta23meoph
40 7190: bhs-nme35pyr-nmgly-betacph40 7190: bhs-nme35pyr-nmgly-betacph
7191: bhs-24oxaz-leu-betapy7191: bras-24oxaz-leu-betapy
7192 : impy-24thiaz-bala-betaphethioa7192: impy-24thiaz-bala-betaphethioa
7193: phhs-ithiadiaz-gly-asppha7193: phhs-ithiadiaz-gly-asppha
7194 : phhs-25methiaz-gly-betapyr 45 7195: phhs-24thioph-gly-betaph7194: phhs-25methiaz-gly-betapyr 45 7195: phhs-24thioph-gly-betaph
7196: dhim-26py-ala-psdap7196: dhim-26py-ala-psdap
7197: ibhs-24thioph-bala-betafu3 7198: ibhs-ithiadiaz-bala-betahb 7199 : bhs-ithiadiaz-gly-betaomebendi 7200: phhs-25oxaz-bala-betabenfu7197: ibhs-24thioph-bala-betafu3 7198: ibhs-ithiadiaz-bala-betahb 7199: bhs-ithiadiaz-gly-betaomebendi 7200: phhs-25oxaz-bala-betabenfu
7201: tolhs-25thiaz-bala-betaipro 5 7202: phhs-25oxaz-bala-betal3bendi7201: tolhs-25thiaz-bala-betaipro 5 7202: phhs-25oxaz-bala-betal3bendi
7203: tolhs-oxadiaz-gly-betahc7203: tolhs-oxadiaz-gly-betahc
7204: ibhs-25thiaz-bala-betadcphtb7204: ibhs-25thiaz-bala-betadcphtb
7205: bhs-me24oxaz-bala-psdap7205: bhs-me24oxaz-bala-psdap
7206: ibhs-nme35pyr-bala-zdapee7206: ibhs-nme35pyr-bala-zdapee
7207 : phhs-24thioph-bala-betainyl7207: phhs-24thioph-bala-betainyl
1010
7208: ibhs-24thioph-gly-zdap7208: ibhs-24thioph-gly-zdap
7209: bhs-25methiaz-ala-betaanaphth7209: bhs-25methiaz-ala-betaanaphth
7210 : tolhs-24thioph-gly-betapyee7210: tolhs-24thioph-gly-betapyee
7211 : phhs-25thiaz-bala-ibsdap7211: phhs-25thiaz-bala-ibsdap
7212 : tolhs-24thiaz-gly-betabenfu 15 7213: bhs-oxadiaz-ala-beta23meoph7212: tolhs-24thiaz-gly-betabenfu 15 7213: bhs-oxadiaz-ala-beta23meoph
7214: bhs-25methiaz-ala-beta3quin7214: bhs-25methiaz-ala-beta3quin
7215: phhs-25thiaz-gly-betaimid7215: phhs-25thiaz-gly-betaimide
7216: ibhs-nme35pyr-bala-beta34dcph7216: ibhs-nme35pyr-bala-beta34dcph
7217: ibhs-oxadiaz-gly-betahcbph 20 7218: ibhs-nme35pyr-gly-aspbzla7217: ibhs-oxadiaz-gly-betahcbph 20 7218: ibhs-nme35pyr-gly-aspbzla
7219: 2py-25oxaz-ala-betapy7219: 2py-25oxaz-ala-betapy
7220: gua-24thiaz-gly-betahdbph7220: gua-24thiaz-gly-betahdbph
7221: phhs-nme35pyr-bala-betaph7221: phhs-nme35pyr-bala-betaph
7222: bhs-nme35pyr-bala-betahdbph7222: bhs-nme35pyr-bala-betahdbph
7223: bhs-24thiaz-gly-betafph7223: bhs-24thiaz-gly-betafph
25 7224: tolhs-25thiaz-bala-zdapch25 7224: tolhs-25thiaz-bala-zdapch
7225: ibhs-24thiaz-gly-betapy7225: ibhs-24thiaz-gly-betapy
7226 : tolhs-nme35pyr-bala-betadito7226: tolhs-nme35pyr-bala-betadito
7227: phhs-25thiaz-bala-betafluo7227: phhs-25thiaz-bala-betafluo
7228: tolhs-24thiaz-gly-betaimid 30 7229: bhs-oxadiaz-gly-betafphe7228: tolhs-24thiaz-gly-betaimide 30 7229: bhs-oxadiaz-gly-betafphe
7230: tolhs-me24thiaz-gly-betaph7230: tolhs-me24thiaz-gly-betaph
7231: bim-53pyrazo-leu-psdap7231: bim-53pyrazo-leu-psdap
7232: thazep-26py-gly-betainyl7232: thazep-26py-gly-betainyl
7233 : tolhs-nme35pyr-bala-betafluo 35 7234: tolhs-25methiaz-bala-betal3bendi7233: tolhs-nme35pyr-bala-betafluo 35 7234: tolhs-25methiaz-bala-betal3bendi
7235: bhs-25thioph-bala-psdap7235: bhs-25thioph-bala-psdap
7236: 2pmhs-24thiaz-gly-betathiome7236: 2 pmhs-24thiaz-gly-betathiome
7237: 2py-25oxaz-gly-betabthioph7237: 2py-25oxaz-gly-beta thioph
7238: bhs-25thiaz-bala-betaoxope7238: bhs-25thiaz-bala-betaoxope
7239: bhs-25oxaz-gly-betapych7239: bhs-25oxaz-gly-betapych
40 7240: ibhs-25oxaz-gly-betahmph40 7240: ibhs-25oxaz-gly-betahmph
7241: bhs-25oxaz-gly-betaet7241: bhs-25oxaz-gly-betaet
7242: gua-26py-gly-betainyl7242: gua-26py-gly-betainyl
7243: bim-53pyrazo-gly-betadcph7243: bim-53pyrazo-gly-betadcph
7244: 2py-25oxaz-bala-aspaba 45 7245: bhs-me25thioph-bala-betadcph7244: 2py-25oxaz-bala-aspaba 45 7245: bhs-me25thioph-bala-betadcph
7246: ibhs-25methiaz-bala-betabpy7246: ibhs-25methiaz-bala-betabpy
7247: bhs-24oxaz-gly-psdap 7248: bhs-25thiaz-bala-zdapch7247: bhs-24oxaz-gly-psdap 7248: bhs-25thiaz-bala-zdapch
7249 : tolhs-24thiaz-bala-betaimid7249: tolhs-24thiaz-bala-betaimide
7250 : ibhs-24thioph-gly-beta34meoph7250: ibhs-24thioph-gly-beta34meoph
7251 : tolhs-25methiaz-bala-betaipr 5 7252: bhs-nme35pyr-bala-betadcphee7251: tolhs-25methiaz-bala-betaipr 5 7252: bhs-nme35pyr-bala-betadcphee
7253: tolhs-oxadiaz-gly-betabph7253: tolhs-oxadiaz-gly-betabph
7254: gua-24thiaz-gly-betaheph7254: gua-24thiaz-gly-betaheph
7255: tolhs-nme35pyr-gly-zdaptb7255: tolhs-nme35pyr-gly-zdaptb
7256: ibhs-25oxaz-bala-betahmo7256: ibhs-25oxaz-bala-betahmo
7257 : bim-me25oxaz-leu-beta34meoph7257: bim-me25oxaz-leu-beta34meoph
10 7258: 2py-24im-ala-betapy10 7258: 2py-24im-ala-betapy
7259: bhs-24thiaz-nmgly-betainyl7259: bhs-24thiaz-nmgly-betainyl
7260: phhs-25thiaz-bala-betaipr7260: phhs-25thiaz-bala-betaipr
7261: bhs-24thiaz-gly-asppha7261: bhs-24thiaz-gly-asppha
7262: 2py-53pyrazo-leu-betadcph 15 7263: bhs-me24thioph-bala-betadcph7262: 2py-53pyrazo-leu-betadcph 15 7263: bhs-me24thioph-bala-betadcph
7264: dhim-26py-gly-betameph7264: dhim-26py-gly-betameph
7265: bhs-nme35pyr-ala-betamesu7265: bhs-nme35pyr-ala-betamesu
7266: ibhs-25oxaz-gly-betabpy7266: ibhs-25oxaz-gly-betabpy
7267: bhs-thiadiaz-gly-psdap 20 7268: bim-25methiaz-leu-zdap7267: bhs-thiadiaz-gly-psdap 20 7268: bim-25methiaz-leu-zdap
7269 : phhs-24thiaz-bala-betabnaphth7269: phhs-24thiaz-bala-betabnaphth
7270: ibhs-nme35pyr-gly-betadmoph7270: ibhs-nme35pyr-gly-betadmoph
7271: 2py-25thiaz-bala-betaheph7271: 2py-25thiaz-bala-betaheph
7272: dhpyrr-24thioph-gly-betapy7272: dhpyrr-24thioph-gly-betapy
7273 : phhs-me24thiaz-gly-betadcph7273: phhs-me24thiaz-gly-betadcph
25 7274: tolhs-24thioph-gly-betahc25 7274: tolhs-24thioph-gly-betahc
7275: bhs-24thiaz-gly-betahdbph7275: bhs-24thiaz-gly-betahdbph
7276: bim-25oxaz-gly-betaph7276: bim-25oxaz-gly-betaph
7277: bim-nme35pyr-bala-aspbzla7277: bim-nme35pyr-bala-aspbzla
7278: tolhs-nme35pyr-gly-zdap 30 7279: bhs-25methiaz-bala-psdapee7278: tolhs-nme35pyr-gly-zdap 30 7279: bhs-25methiaz-bala-psdapee
7280: 2py-me24thiaz-leu-betapy7280: 2py-me24thiaz-leu-betapy
7281: bhs-oxadiaz-nmgly-beta3quin7281: bhs-oxadiaz-nmgly-beta3quin
7282: tolhs-24thiaz-gly-betahph7282: tolhs-24thiaz-gly-betahph
7283: bhs-25thiaz-phg-betameph 35 7284: tolhs-me25oxaz-leu-betapy7283: bhs-25thiaz-phg-betameph 35 7284: tolhs-me25oxaz-leu-betapy
7285: 2py-24thioph-bala-betafluo7285: 2py-24thioph-bala-betafluo
7286 : tolhs-25oxaz-bala-betaheph7286: tolhs-25oxaz-bala-betaheph
7287 : ibhs-25thiaz-bala-betabenfu7287: ibhs-25thiaz-bala-betabenfu
7288: phhs-nme35pyr-gly-ibsdap7288: phhs-nme35pyr-gly-ibsdap
7289 : ibhs-24thioph-bala-betarnethi7289: ibhs-24thioph-bala-betarnethi
40 7290 : ibhs-24thioph-bala-betaphethio40 7290: ibhs-24thioph-bala-betaphethio
7291: ibhs-24thioph-gly-suabu7291: ibhs-24thioph-gly-suabu
7292 : bhs-25methiaz-bala-betabph7292: bras-25methiaz-bala-betabph
7293 : 2py-25methiaz-bala-betabnaphth7293: 2py-25methiaz-bala-betabnaphth
7294: tolhs-24thioph-bala-betahni 45 7295: bhs-nme35pyr-gly-betainyl7294: tolhs-24thioph-bala-betahni 45 7295: bhs-nme35pyr-gly-betainyl
7296: ibhs-25methiaz-gly-betadito7296: ibhs-25methiaz-gly-betadito
7297 : impy-25methiaz-gly-betacbph 7298: ibhs-oxadiaz-gly-betafphe7297: impy-25methiaz-gly-betacbph 7298: ibhs-oxadiaz-gly-betafphe
7299: bhs-oxadiaz-gly-betambiph7299: bhs-oxadiaz-gly-betambiph
7300: bhs-nme35pyr-ala-betathio37300: bhs-nme35pyr-ala-betathio3
7301: bhs-25methiaz-gly-betapytb 5 7302: 2py-25oxaz-bala-zdap7301: bhs-25methiaz-gly-betapytb 5 7302: 2py-25oxaz-bala-zdap
7303: phhs-24thiaz-gly-betahmo7303: phhs-24thiaz-gly-betahmo
7304: bim-24thioph-ala-psdap7304: bim-24thioph-ala-psdap
7305: bim-me24oxaz-ala-betadcph7305: bim-me24oxaz-ala-betadcph
7306: bhs-24thioph-gly-betafu27306: bhs-24thioph-gly-betafu2
7307: ibhs-25thiaz-gly-betapytb7307: ibhs-25thiaz-gly-betapytb
10 7308: ibhs-24thioph-bala-betameph10 7308: ibhs-24thioph-bala-betameph
7309: phhs-oxadiaz-gly-betafu37309: phhs-oxadiaz-gly-betafu3
7310: ibhs-25thiaz-gly-betambiph7310: ibhs-25thiaz-gly-betambiph
7311 : ibhs-oxadiaz-gly-betathioph7311: ibhs-oxadiaz-gly-betathioph
7312 : phhs-25methiaz-bala-betahbcph 15 7313: bim-24thiaz-gly-zdap7312: phhs-25methiaz-bala-betahbcph 15 7313: bim-24thiaz-gly-zdap
7314: bhs-25f r-bala-betadcph7314: bras-25f r-bala-betadcph
7315: tolhs-oxadiaz-bala-betatrif7315: tolhs-oxadiaz-bala-betatrif
7316: bhs-24im-bala-betadcph7316: bras-24im-bala-betadcph
7317: tolhs-25methiaz-bala-zdap 20 7318: phhs-ithiadiaz-gly-betadcphee7317: tolhs-25methiaz-bala-zdap 20 7318: phhs-ithiadiaz-gly-betadcphee
7319: ibhs-25methiaz-bala-betaftrif7319: ibhs-25methiaz-bala-betaftrif
7320: tolhs-nme35pyr-gly-betapy7320: tolhs-nme35pyr-gly-betapy
7321: phhs-25methiaz-gly-betabmph7321: phhs-25methiaz-gly-betabmph
7322: dhthi-42nmeim-bala-psdap7322: dhthi-42nmeim-bala-psdap
7323 : tolhs-24thiaz-bala-beta34dcph7323: tolhs-24thiaz-bala-beta34dcph
25 7324: tolhs-me25thiaz-leu-zdap25 7324: tolhs-me25thiaz-leu-zdap
7325: 2py-me25thiaz-bala-betaph7325: 2py-me25thiaz-bala-betaph
7326: bhs-25methiaz-ala-zdap7326: bhs-25methiaz-ala-zdap
7327: bhs-24thioph-nmgly-betadmph7327: bhs-24thioph-nmgly-betadmph
7328: bhs-24thiaz-leu-zdap 30 7329: ibhs-24thiaz-bala-betabdimo7328: bhs-24thiaz-leu-zdap 30 7329: ibhs-24thiaz-bala-betabdimo
7330: tolhs-25oxaz-gly-psdaptb7330: tolhs-25oxaz-gly-psdaptb
7331 : phhs-me24thioph-ala-beta34meoph7331: phhs-me24thioph-ala-beta34meoph
7332: bim-25thiaz-phg-zdap7332: bim-25thiaz-phg-zdap
7333: ibhs-24thiaz-gly-betapym 35 7334: bim-me25thiaz-ala-betapy7333: ibhs-24thiaz-gly-betapym 35 7334: bim-me25thiaz-ala-betapy
7335: 2py-42oxaz-bala-betapy7335: 2py-42oxaz-bala-betapy
7336: bim-42oxaz-gly-be apy7336: bim-42oxaz-gly-be apy
7337: bhs-25oxaz-gly-betapytb7337: bhs-25oxaz-gly-betapytb
7338: bhs-25oxaz-gly-betapyee7338: bhs-25oxaz-gly-betapyee
7339: gua-42pym-gly-betabdimo7339: gua-42pym-gly-betabdimo
40 7340: bhs-26py-gly-betameph40 7340: bhs-26py-gly-betameph
7341: impy-26py-gly-psdap7341: impy-26py-gly-psdap
7342: bhs-25oxaz-bala-betabediox7342: bras-25oxaz-bala-betabediox
7343: tolhs-oxadiaz-bala-zdapee7343: tolhs-oxadiaz-bala-zdapee
7344: bhs-nme35pyr-gly-betathiobe 45 7345: tolhs-25methiaz-gly-betaomebendi7344: bhs-nme35pyr-gly-betathiobe 45 7345: tolhs-25methiaz-gly-betaomebendi
7346: ibhs-24thioph-bala-betampy7346: ibhs-24thioph-bala-betampy
7347 : ibhs-24thiaz-bala-betapbiph 7348: ibhs-24thioph-bala-psdapch7347: ibhs-24thiaz-bala-betapbiph 7348: ibhs-24thioph-bala-psdapch
7349: phhs-24thiaz-bala-betaet7349: phhs-24thiaz-bala-betaet
7350: bhs-25methiaz-bala-betaoxaz7350: bhs-25methiaz-bala-betaoxaz
7351 : bhs-me24thioph-leu-betadcph 5 7352: 2py-25thioph-bala-betadcph7351: bhs-me24thioph-leu-betadcph 5 7352: 2py-25thioph-bala-betadcph
7353 : tolhs-ithiadiaz-gly-betathiobe7353: tolhs-ithiadiaz-gly-betathiobe
7354 : bhs-25methiaz-bala-betathiome7354: bhs-25methiaz-bala-betathiome
7355 : bhs-oxadiaz-gly-betaoxope7355: bhs-oxadiaz-gly-betaoxope
7356 : bhs-24thiaz-bala-betabnaphth7356: bras-24thiaz-bala-betabnaphth
7357: phhs-nme35pyr-bala-betahph 10 7358: ibhs-25thiaz-gly-zdaptb7357: phhs-nme35pyr-bala-betahph 10 7358: ibhs-25thiaz-gly-zdaptb
7359: bhs-oxadiaz-ala-betahph7359: bras-oxadiaz-ala-betahph
7360 : ibhs-42nmeim-gly-betameph7360: ibhs-42nmeim-gly-betameph
7361: ibhs-24thioph-bala-betaol7361: ibhs-24thioph-bala-betaol
7362 : tolhs-24thioph-bala-betah35dc 15 7363: ibhs-24thiaz-gly-betadcphtb7362: tolhs-24thioph-bala-betah35dc 15 7363: ibhs-24thiaz-gly-betadcphtb
7364: bhs-25thiaz-gly-betabenfu7364: bhs-25thiaz-gly-betabenfu
7365: tolhs-ithiadiaz-bala-betaoxope7365: tolhs-ithiadiaz-bala-betaoxope
7366: ibhs-oxadiaz-gly-betaheph7366: ibhs-oxadiaz-gly-betaheph
7367 : bhs-24thiaz-ala-betacthioph 20 7368: ibhs-24thioph-gly-betapbiph7367: bhs-24thiaz-ala-betacthioph 20 7368: ibhs-24thioph-gly-betapbiph
7369: bhs-oxadiaz-nmgly-betathio37369: bhs-oxadiaz-nmgly-betathio3
7370: bim-me25thiaz-ala-betaph7370: bim-me25thiaz-ala-betaph
7371: ibhs-oxadiaz-gly-betahph7371: ibhs-oxadiaz-gly-betahph
7372: gua-42pym-gly-betampy7372: gua-42pym-gly-betampy
7373: tolhs-25oxaz-gly-betafu2 257373: tolhs-25oxaz-gly-betafu2 25
7374: phhs-nme35pyr-bala-betaoxope7374: phhs-nme35pyr-bala-betaoxope
7375: ibhs-nme35pyr-bala-betaimid7375: ibhs-nme35pyr-bala-betaimid
7376: bhs-25oxaz-gly-psdapee7376: bhs-25oxaz-gly-psdapee
7377: bhs-25thiaz-nmgly-betacph7377: bhs-25thiaz-nmgly-betacph
7378: tolhs-24thioph-bala-aspbzla 30 7379: ibhs-25methiaz-gly-psdapee7378: tolhs-24thioph-bala-aspbzla 30 7379: ibhs-25methiaz-gly-psdapee
7380: tolhs-25thiaz-gly-betafph7380: tolhs-25thiaz-gly-betafph
7381: phhs-ithiadiaz-gly-betaphethio7381: phhs-ithiadiaz-gly-betaphethio
7382 : ibhs-ithiadiaz-bala-betafu37382: ibhs-ithiadiaz-bala-betafu3
7383: ibhs-25oxaz-bala-betadcphee 35 7384: phhs-25methiaz-gly-betaanaphth7383: ibhs-25oxaz-bala-betadcphee 35 7384: phhs-25methiaz-gly-betaanaphth
7385 : phhs-ithiadiaz-gly-zdapee7385: phhs-ithiadiaz-gly-zdapee
7386: bim-ithiadiaz-gly-aspibua7386: bim-ithiadiaz-gly-aspibua
7387 : phhs-25oxaz-bala-betaheph7387: phhs-25oxaz-bala-betaheph
7388: tolhs-25methiaz-gly-zdaptb7388: tolhs-25methiaz-gly-zdaptb
7389 : bhs-oxadiaz-ala-betainyl 407389: bhs-oxadiaz-ala-betainyl 40
7390: tolhs-24thιoph-gly-ιbsdap7390: tolhs-24thιoph-gly-ιbsdap
7391 : 2py-nme35pyr-gly-zdap7391: 2py-nme35pyr-gly-zdap
7392: bim-24thiaz-bala-betahc7392: bim-24thiaz-bala-betahc
7393: 2py-me25thioph-bala-zdap7393: 2py-me25thioph-bala-zdap
7394: imhs-25oxaz-bala-psdap7394: imhs-25oxaz-bala-psdap
45 7395: bhs-24thioph-bala-betahni45 7395: bras-24thioph-bala-betahni
7396: tolhs-24thioph-gly-betaet7396: tolhs-24thioph-gly-betaet
7397: ibhs-25thiaz-gly-betahdbph 7398: phhs-nme35pyr-gly-psdapee7397: ibhs-25thiaz-gly-betahdbph 7398: phhs-nme35pyr-gly-psdapee
7399 : phhs-oxadiaz-gly-betahbcph7399: phhs-oxadiaz-gly-betahbcph
7400: hyd-24thioph-bala-betameph7400: hyd-24thioph-bala-betameph
7401: phhs-25thiaz-bala-busu2be 5 7402: tolhs-24thioph-gly-betahph7401: phhs-25thiaz-bala-busu2be 5 7402: tolhs-24thioph-gly-betahph
7403: 2py-24thioph-bala-betaheph7403: 2py-24thioph-bala-betaheph
7404 : tolhs-nme35pyr-bala-betal3bendi7404: tolhs-nme35pyr-bala-betal3bendi
7405: bhs-ithiadiaz-gly-betahb7405: bhs-ithiadiaz-gly-betahb
7406: bhs-oxadiaz-bala-betaibph7406: bhs-oxadiaz-bala-betaibph
7407 : ibhs-25methiaz-gly-betafphe7407: ibhs-25methiaz-gly-betafphe
7408: phhs-24thiaz-gly-betahph7408: phhs-24thiaz-gly-betahph
7409: 2py-24thioph-leu-psdap7409: 2py-24thioph-leu-psdap
7410: phhs-nme35pyr-bala-betadcphtb7410: phhs-nme35pyr-bala-betadcphtb
7411 : ibhs-24thiaz-gly-betadcphch7411: ibhs-24thiaz-gly-betadcphch
7412: 2py-24thiophme-ala-betapy 15 7413: bhs-24thioph-bala-psdaptb7412: 2py-24thiophme-ala-betapy 15 7413: bhs-24thioph-bala-psdaptb
7414 : ibhs-25methiaz-bala-betabenfu7414: ibhs-25methiaz-bala-betabenfu
7415: 2py-ithiadiaz-leu-betapy7415: 2py-ithiadiaz-leu-betapy
7416: bim-42nmeim-leu-psdap7416: bim-42nmeim-leu-psdap
7417: gua-42pym-gly-betahmph 2o 7418: phhs-25methiaz-gly-betabpy7417: gua-42pym-gly-betahmph 2o 7418: phhs-25methiaz-gly-betabpy
7419 : tolhs-24thioph-gly-betaamibe7419: tolhs-24thioph-gly-betaamibe
7420: bhs-25oxaz-bala-psdapee7420: bras-25oxaz-bala-psdapee
7421 : 2pmhs-25methiaz-bala-betamethioph7421: 2 pmhs-25methiaz-bala-betamethioph
7422 : dimethpym-24thiaz-gly-betahdcph7422: dimethpym-24thiaz-gly-betahdcph
7423: bhs-24thiaz-bala-betah35dc7423: bhs-24thiaz-bala-betah35dc
7424: tolhs-24thioph-bala-betabenfu7424: tolhs-24thioph-bala-betabenfu
7425: bim-24thioph-ala-betadcph7425: bim-24thioph-ala-betadcph
7426: phhs-25methiaz-bala-betamesu7426: phhs-25methiaz-bala-betamesu
7427 : bhs-nme35pyr-bala-betathiobe7427: bhs-nme35pyr-bala-betathiobe
7428: phhs-ithiadiaz-gly-zdap 30 7429: phhs-ithiadiaz-bala-betameph7428: phhs-ithiadiaz-gly-zdap 30 7429: phhs-ithiadiaz-bala-betameph
7430: tolhs-nme35pyr-bala-betambiph7430: tolhs-nme35pyr-bala-betambiph
7431: bhs-35fur-leu-betapy7431: bhs-35fur-leu-betapy
7432: phhs-25thiaz-gly-betaanaphth7432: phhs-25thiaz-gly-betaanaphth
7433: bhs-me24thiaz-gly-betaph 35 7434: bhs-25methiaz-bala-betameph7433: bhs-me24thiaz-gly-betaph 35 7434: bhs-25methiaz-bala-betameph
7435: ibhs-nme35pyr-bala-psdaptb7435: ibhs-nme35pyr-bala-psdaptb
7436 : phhs-me24thioph-bala-beta34meoph7436: phhs-me24thioph-bala-beta34meoph
7437 : bhs-25thiaz-gly-betaomebendi7437: bhs-25thiaz-gly-betaomebendi
7438: bhs-25thiaz-gly-betadbph7438: bhs-25thiaz-gly-betadbph
7439: bhs-25methiaz-gly-betamethi7439: bhs-25methiaz-gly-betamethi
40 7440: gua-24oxaz-gly-betaet40 7440: gua-24oxaz-gly-betet
7441: phhs-24thioph-gly-suabu7441: phhs-24thioph-gly-suabu
7442: bhs-42nmeim-bala-beta35dbph7442: bhs-42nmeim-bala-beta35dbph
7443: ibhs-25thiaz-gly-betahmo7443: ibhs-25thiaz-gly-betahmo
7444: bhs-24thiaz-gly-zdapee 45 7445: ibhs-24thiaz-bala-betahdbph7444: bhs-24thiaz-gly-zdapee 45 7445: ibhs-24thiaz-bala-betahdbph
7446: ibhs-24thioph-gly-betahb7446: ibhs-24thioph-gly-betahb
7447: bim-25oxaz-gly-betadtrif 7448: bhs-24thioph-ala-betahph7447: bim-25oxaz-gly-betadtrif 7448: bhs-24thioph-ala-betahph
7449 : bhs-25oxaz-leu-psdap7449: bras-25oxaz-leu-psdap
7450 : bhs-nme35pyr-bala-betainyl7450: bhs-nme35pyr-bala-betainyl
7451: bhs-ithiadiaz-ala-beta3quin 5 7452: phhs-24thiaz-bala-betahdcph7451: bhs-ithiadiaz-ala-beta3quin 5 7452: phhs-24thiaz-bala-betahdcph
7453: bim-me25thiaz-leu-betapy7453: bim-me25thiaz-leu-betapy
7454: 2py-25thiaz-gly-betainyl7454: 2py-25thiaz-gly-betainyl
7455 : tolhs-25oxaz-gly-betal3bendi7455: tolhs-25oxaz-gly-betal3bendi
7456 : tolhs-24thiaz-bala-beta4bph7456: tolhs-24thiaz-bala-beta4bph
7457 : tolhs-ithiadiaz-bala-betampy7457: tolhs-ithiadiaz-bala-betampy
10 7458: bhs-25oxaz-gly-betafphe10 7458: bhs-25oxaz-gly-betafphe
7459 : tolhs-ithiadiaz-bala-betahmph7459: tolhs-ithiadiaz-bala-betahmph
7460 : ibhs-25thiaz-gly-betaphethioa7460: ibhs-25thiaz-gly-betaphethioa
7461: ibhs-24thioph-bala-betacph7461: ibhs-24thioph-bala-betacph
7462 : bhs-25methiaz-bala-betaamibe 15 7463: phhs-me25thioph-leu-psdap7462: bhs-25methiaz-bala-betaamibe 15 7463: phhs-me25thioph-leu-psdap
7464 : 2py-me25thiaz-leu-beta34meoph7464: 2py-me25thiaz-leu-beta34meoph
7465 : ibhs-ithiadiaz-bala-betaamibe7465: ibhs-ithiadiaz-bala-betaamibe
7466: phhs-oxadiaz-bala-betaoxaz7466: phhs-oxadiaz-bala-betaoxaz
7467 : phhs-nme35pyr-gly-betaphethioa 20 7468: bhs-24thiaz-gly-betabpy7467: phhs-nme35pyr-gly-betaphethioa 20 7468: bhs-24thiaz-gly-betabpy
7469 : tolhs-ithiadiaz-bala-betamethioph7469: tolhs-ithiadiaz-bala-betamethioph
7470: bim-24oxaz-leu-psdap7470: bim-24oxaz-leu-psdap
7471: bhs-thiadiaz-leu-psdap7471: bhs-thiadiaz-leu-psdap
7472 : 2py-oxadiaz-gly-aspaba7472: 2py-oxadiaz-gly-aspaba
7473: 2py-42nmeim-gly-psdap7473: 2py-42nmeim-gly-psdap
25 7474 : impy-25methiaz-gly-betathiobe25 7474: impy-25methiaz-gly-betathiobe
7475: tolhs-25oxaz-bala-betampy7475: tolhs-25oxaz-bala-betampy
7476: ibhs-25oxaz-bala-aspbzla7476: ibhs-25oxaz-bala-aspbzla
7477: ibhs-25thiaz-bala-betaamibe7477: ibhs-25thiaz-bala-betaamibe
7478: phhs-24thioph-gly-betahmph 30 7479: ibhs-25thiaz-bala-betaet7478: phhs-24thioph-gly-betahmph 30 7479: ibhs-25thiaz-bala-betet
7480 : ibhs-25methiaz-bala-betaoxope7480: ibhs-25methiaz-bala-betaoxope
7481: bhs-nme35pyr-bala-betaibph7481: bhs-nme35pyr-bala-betaibph
7482: tolhs-25oxaz-gly-betapbiph7482: tolhs-25oxaz-gly-betapbiph
7483: 2py-25methiaz-bala-suabu 35 7484: tolhs-ithiadiaz-gly-betadcph7483: 2py-25methiaz-bala-suabu 35 7484: tolhs-ithiadiaz-gly-betadcph
7485: 2pmhs-42nmeim-gly-betaoxaz7485: 2 pmhs-42nmeim-gly-betaoxaz
7486 : ibhs-25methiaz-bala-psdaptb7486: ibhs-25methiaz-bala-psdaptb
7487 : bhs-25methiaz-bala-betaomebendi7487: bhs-25methiaz-bala-betaomebendi
7488 : impy-25oxaz-gly-beta23meoph7488: impy-25oxaz-gly-beta23meoph
7489: bhs-nme35pyr-gly-psdaptb7489: bhs-nme35pyr-gly-psdaptb
40 7490: bhs-24thioph-gly-betacph40 7490: bhs-24thioph-gly-betacph
7491: bhs-25oxaz-bala-aspibua7491: bras-25oxaz-bala-aspibua
7492: tolhs-nme35pyr-bala-zdapee7492: tolhs-nme35pyr-bala-zdapee
7493: bhs-25methiaz-bala-betamesu7493: bras-25methiaz-bala-betamesu
7494: 2py-42oxaz-leu-betadcph 45 7495: ibhs-25thiaz-gly-betadmoph7494: 2py-42oxaz-leu-betadcph 45 7495: ibhs-25thiaz-gly-betadmoph
7496: bhs-nme35pyr-bala-betaipro7496: bhs-nme35pyr-bala-betaipro
7497: bim-42nmeim-gly-betainyl 7498: phhs-nme35pyr-gly-betaph7497: bim-42nmeim-gly-betainyl 7498: phhs-nme35pyr-gly-betaph
7499: tolhs-25methiaz-bala-betafph7499: tolhs-25methiaz-bala-betafph
7500: tolhs-24thioph-bala-psdap7500: tolhs-24thioph-bala-psdap
7501: bhs-25thioph-ala-betameph 5 7502: tolhs-25oxaz-bala-betaoxaz7501: bhs-25thioph-ala-betameph 5 7502: tolhs-25oxaz-bala-betaoxaz
7503: phhs-25thiaz-bala-betahmofu7503: phhs-25thiaz-bala-betahmofu
7504: bim-24thioph-gly-asppha7504: bim-24thioph-gly-asppha
7505: phhs-25oxaz-bala-betatbuph7505: phhs-25oxaz-bala-betatbuph
7506: bhs-oxadiaz-ala-betamesu7506: bras-oxadiaz-ala-betamesu
7507 : ibhs-24thioph-gly-betabthioph7507: ibhs-24thioph-gly-betabthioph
10 7508: 2pmhs-24thiaz-bala-betahph10 7508: 2 pmhs-24thiaz-bala-betahph
7509: phhs-25oxaz-gly-betabthioph7509: phhs-25oxaz-gly-beta thioph
7510 : phhs-24thioph-bala-betaoxope7510: phhs-24thioph-bala-betaoxope
7511: bhs-ithiadiaz-bala-ibsdap7511: bhs-ithiadiaz-bala-ibsdap
7512: ibhs-25thiaz-gly-zdapee 15 7513: bhs-25oxaz-bala-betafbph7512: ibhs-25thiaz-gly-zdapee 15 7513: bhs-25oxaz-bala-betafbph
7514: tolhs-25oxaz-gly-betabthioph7514: tolhs-25oxaz-gly-betabthioph
7515 : bhs-me25thioph-bala-beta34meoph7515: bhs-me25thioph-bala-beta34meoph
7516: impy-25methiaz-gly-betaipr7516: impy-25methiaz-gly-betaipr
7517 : phhs-25thiaz-gly-betadcphtb 20 7518: bhs-24thiaz-bala-betaipr7517: phhs-25thiaz-gly-betadcphtb 20 7518: bhs-24thiaz-bala-betaipr
7519: tolhs-24thioph-gly-psdapch7519: tolhs-24thioph-gly-psdapch
7520: bhs-me24oxaz-gly-betapy7520: bhs-me24oxaz-gly-betapy
7521: phhs-nme35pyr-bala-betathio37521: phhs-nme35pyr-bala-betathio3
7522: bhs-nme35pyr-gly-betabenfu7522: bhs-nme35pyr-gly-betabenfu
7523 : phhs-25methiaz-bala-betadito7523: phhs-25methiaz-bala-betadito
25 7524 : ibhs-nme35pyr-bala-betadcphtb25 7524: ibhs-nme35pyr-bala-betadcphtb
7525: tolhs-24thioph-gly-aspaba7525: tolhs-24thioph-gly-aspaba
7526: 2py-35thioph-bala-psdap7526: 2py-35thioph-bala-psdap
7527: bim-me25thiaz-bala-psdap7527: bim-me25thiaz-bala-psdap
7528: gua-25thioph-gly-beta3quin 30 7529: gua-42pym-gly-betathiome7528: gua-25thioph-gly-beta3quin 30 7529: gua-42pym-gly-betathiome
7530 : phhs-25methiaz-gly-beta23meoph7530: phhs-25methiaz-gly-beta23meoph
7531: phhs-25thiaz-gly-betadbph7531: phhs-25thiaz-gly-betadbph
7532: tolhs-24thiaz-gly-ibsdap7532: tolhs-24thiaz-gly-ibsdap
7533: bim-25oxaz-ala-betadcph 35 7534: 2py-25thiaz-bala-psdap7533: bim-25oxaz-ala-betadcph 35 7534: 2py-25thiaz-bala-psdap
7535: phhs-ithiadiaz-bala-betahbcph7535: phhs-ithiadiaz-bala-betahbcph
7536: ibhs-ithiadiaz-gly-betahmo7536: ibhs-ithiadiaz-gly-betahmo
7537: bhs-25oxaz-gly-betadito7537: bras-25oxaz-gly-betadito
7538 : 2pmhs-25oxaz-gly-betacthioph7538: 2 pmhs-25oxaz-gly-betacthioph
7539: bhs-me25thiaz-ala-beta34meoph7539: bhs-me25thiaz-ala-beta34meoph
40 7540: ibhs-25thiaz-gly-betahmph40 7540: ibhs-25thiaz-gly-betahmph
7541 : bhs-nme35pyr-bala-betahc7541: bhs-nme35pyr-bala-betahc
7542 : tolhs-24thioph-bala-busu2be7542: tolhs-24thioph-bala-busu2be
7543: ibhs-nme35pyr-gly-betahph7543: ibhs-nme35pyr-gly-betahph
7544 : bim-2 thioph-gly-betaanaphth 45 7545: phhs-oxadiaz-bala-csdap7544: bim-2 thioph-gly-betaanaphth 45 7545: phhs-oxadiaz-bala-csdap
7546: phhs-25thiaz-gly-psdaptb7546: phhs-25thiaz-gly-psdaptb
7547: bim-24oxaz-leu-betadcph 7548: phhs-24thiaz-bala-betahc7547: bim-24oxaz-leu-betadcph 7548: phhs-24thiaz-bala-betahc
7549: phhs-25methiaz-bala-aspaba7549: phhs-25methiaz-bala-aspaba
7550: tolhs-25oxaz-gly-betacph7550: tolhs-25oxaz-gly-betacph
7551: bhs-24thiaz-gly-betahni7551: bhs-24thiaz-gly-betahni
5 7552: ibhs-25oxaz-gly-busu2be5 7552: ibhs-25oxaz-gly-busu2be
7553: bhs-24thiaz-bala-betahmofu7553: bras-24thiaz-bala-betahmofu
7554: phhs-25oxaz-bala-betaipro7554: phhs-25oxaz-bala-betaipro
7555: impy-24thiaz-gly-betacbph7555: impy-24thiaz-gly-betacbph
7556 : ibhs-25methiaz-bala-betafph7556: ibhs-25methiaz-bala-betafph
7557 : tolhs-24thiaz-gly-betathiobe 10 7558 : ιbhs-ιthιadιaz-bala-beta4bph7557: tolhs-24thiaz-gly-betathiobe 10 7558: ιbhs-ιthιadιaz-bala-beta4bph
7559: bhs-24thiaz-bala-betambiph7559: bras-24thiaz-bala-betambiph
7560: gua-24thiaz-gly-betathiobe7560: gua-24thiaz-gly-betathiobe
7561: bgua-24thiaz-gly-betapy7561: bgua-24thiaz-gly-betapy
7562 : tolhs-ithiadiaz-bala-betathioph 15 7563: bhs-42pym-gly-betacph7562: tolhs-ithiadiaz-bala-betathioph 15 7563: bhs-42pym-gly-betacph
7564 : phhs-ithiadiaz-bala-betadito7564: phhs-ithiadiaz-bala-betadito
7565: bhs-nme35pyr-bala-aspaba7565: bhs-nme35pyr-bala-aspaba
7566: bhs-24thioph-bala-betaipr7566: bhs-24thioph-bala-betaipr
7567 : ibhs-24thioph-bala-betaanaphth 2o 7568: dhpyrr-26py-gly-betapy7567: ibhs-24thioph-bala-betaanaphth 2o 7568: dhpyrr-26py-gly-betapy
7569 : tolhs-25methiaz-bala-betaomebendi7569: tolhs-25methiaz-bala-betaomebendi
7570: bhs-ithiadiaz-bala-betahph7570: bhs-ithiadiaz-bala-betahph
7571 : bhs-nme35pyr-gly-beta4bph7571: bhs-nme35pyr-gly-beta4bph
7572: bim-oxadiaz-gly-aspbzla7572: bim-oxadiaz-gly-aspbzla
7573 : phhs-25thiaz-bala-betabnaphth7573: phhs-25thiaz-bala-betabnaphth
7574: phhs-24thioph-gly-betaipro7574: phhs-24thioph-gly-betaipro
7575: phhs-25thiaz-gly-beta4bph7575: phhs-25thiaz-gly-beta4bph
7576: ibhs-25thiaz-bala-betathio37576: ibhs-25thiaz-bala-betathio3
7577: ibhs-25thiaz-bala-betabpy7577: ibhs-25thiaz-bala-betabpy
7578: phhs-oxadiaz-bala-beta34dcph 30 7579: bhs-25oxaz-bala-betaomebendi7578: phhs-oxadiaz-bala-beta34dcph 30 7579: bhs-25oxaz-bala-betaomebendi
7580 : tolhs-24thiaz-gly-betamethioph7580: tolhs-24thiaz-gly-betamethioph
7581: 2py-42nmeim-bala-betapbiph7581: 2py-42nmeim-bala-betapbiph
7582: ibhs-oxadiaz-gly-beta35dbph7582: ibhs-oxadiaz-gly-beta35dbph
7583 : bhs-nme35pyr-bala-beta23meoph 35 7584: tolhs-nme35pyr-gly-betabthioph7583: bhs-nme35pyr-bala-beta23meoph 35 7584: tolhs-nme35pyr-gly-betabthioph
7585: tolhs-oxadiaz-gly-betabmph7585: tolhs-oxadiaz-gly-betabmph
7586: bhs-25thiaz-ala-betadcph7586: bhs-25thiaz-ala-betadcph
7587: 2py-42pym-ala-betameph7587: 2py-42pym-ala-betameph
7588: bhs-24thiaz-bala-betameph7588: bras-24thiaz-bala-betameph
7589: ibhs-25thiaz-gly-betaibph7589: ibhs-25thiaz-gly-betaibph
40 7590 : tolhs-ithiadiaz-gly-betambiph40 7590: tolhs-ithiadiaz-gly-betambiph
7591: bhs-triaz-leu-betadcph7591: bras-triaz-leu-betadcph
7592 : tolhs-25oxaz-gly-betaphethio7592: tolhs-25oxaz-gly-betaphethio
7593 : tolhs-24thioph-bala-betahdcph7593: tolhs-24thioph-bala-betahdcph
7594: tolhs-25oxaz-gly-betafluo 45 7595: bhs-me25oxaz-ala-beta34meoph7594: tolhs-25oxaz-gly-betafluo 45 7595: bhs-me25oxaz-ala-beta34meoph
7596: bhs-24thioph-bala-zdap7596: bras-24thioph-bala-zdap
7597: ibhs-oxadiaz-gly-betaipr 7598: tolhs-25methiaz-bala-betahdbph7597: ibhs-oxadiaz-gly-betaipr 7598: tolhs-25methiaz-bala-betahdbph
7599: bhs-me25thioph-leu-zdap7599: bhs-me25thioph-leu-zdap
7600: tolhs-24thiaz-gly-betadmoph7600: tolhs-24thiaz-gly-betadmoph
7601: phhs-25thiaz-gly-betaftrif 5 7602: tolhs-25methiaz-gly-betahmofu7601: phhs-25thiaz-gly-betaftrif 5 7602: tolhs-25methiaz-gly-betahmofu
7603 : bhs-oxadiaz-bala-betaphethioa7603: bras-oxadiaz-bala-betaphethioa
7604: phhs-25thiaz-bala-betadmph7604: phhs-25thiaz-bala-betadmph
7605: phhs-24thiaz-gly-betapych7605: phhs-24thiaz-gly-betapych
7606 : bhs-me24thiaz-gly-beta34meoph7606: bhs-me24thiaz-gly-beta34meoph
7607: bhs-24thioph-gly-betahni7607: bhs-24thioph-gly-betahni
10 7608: bhs-25thiaz-gly-betadcphch10 7608: bhs-25thiaz-gly-betadcphch
7609 : tolhs-oxadiaz-bala-betamethi7609: tolhs-oxadiaz-bala-betamethi
7610: ibhs-25methiaz-gly-betameph7610: ibhs-25methiaz-gly-betameph
7611: phhs-25oxaz-gly-beta4bph7611: phhs-25oxaz-gly-beta4bph
7612: tolhs-24thiaz-gly-aspibua 15 7613: 2py-24thiaz-gly-betatbuph7612: tolhs-24thiaz-gly-aspibua 15 7613: 2py-24thiaz-gly-betatbuph
7614: phhs-oxadiaz-gly-betah35dc7614: phhs-oxadiaz-gly-betah35dc
7615: phhs-ithiadiaz-gly-betapy7615: phhs-ithiadiaz-gly-betapy
7616 : bhs-25oxaz-bala-betabthioph7616: bhs-25oxaz-bala-betabthioph
7617 : tolhs-oxadiaz-gly-betathiobe 20 7618: bhs-25thiaz-gly-betahdbph7617: tolhs-oxadiaz-gly-betathiobe 20 7618: bhs-25thiaz-gly-betahdbph
7619: ibhs-25oxaz-gly-betahc7619: ibhs-25oxaz-gly-betahc
7620: 2py-35thioph-bala-betadcph7620: 2py-35thioph-bala-betadcph
7621: bim-me24thiaz-leu-beta34meoph7621: bim-me24thiaz-leu-beta34meoph
7622 : tolhs-24thiaz-bala-betafphe7622: tolhs-24thiaz-bala-betafphe
7623: 2py-26py-phg-zdap7623: 2py-26py-phg-zdap
25 7624: bhs-24thioph-gly-beta34meoph 7625: tolhs-oxadiaz-bala-betamethioph 7626: phhs-nme35pyr-bala-betamethi 7627: bhs-ithiadiaz-ala-betahph 7628: phhs-25oxaz-gly-betafu2 30 7629: bhs-nme35pyr-bala-zdapch 7630: bhs-24thioph-gly-aspaba 7631: tolhs-25thiaz-gly-betadmoph 7632 : tolhs-24thioph-bala-betatos 7633: bhs-25oxaz-bala-betadito 35 7634: bhs-53pyrazo-leu-psdap 7635: ibhs-oxadiaz-gly-betaipro 7636: 2py-nme35pyr-gly-asppha 7637: thpy -25thiaz-gly-betadcph 7638: gua-25thiaz-gly-betaftrif 7639: bim-nme35pyr-bala-zdap25 7624: bhs-24thioph-gly-beta34meoph 7625: tolhs-oxadiaz-bala-betamethioph 7626: phhs-nme35pyr-bala-betamethi 7627: bhs-ithiadiaz-ala-betahph 7628: phhs-25oxaz-gly-betafhs 30 7629 -nme35pyr-bala-zdapch 7630: bhs-24thioph-gly-aspaba 7631: tolhs-25thiaz-gly-betadmoph 7632: tolhs-24thioph-bala-betatos 7633: bhs-25oxaz-bala-betadito 35 7634: bhs-53uyzo -psdap 7635: ibhs-oxadiaz-gly-betaipro 7636: 2py-nme35pyr-gly-asppha 7637: thpy -25thiaz-gly-betadcph 7638: gua-25thiaz-gly-betaftrif 7639: bim-nme35pyr-bala-zdap
40 7640: phhs-25thiaz-gly-betapym 7641: bim-42nmeim-ala-psdap 7642 : bhs-24thioph-bala-beta35dbph 7643: tolhs-25oxaz-bala-betafph 7644: tolhs-25methiaz-gly-betaimid 45 7645: phhs-me25oxaz-bala-beta34meoph 7646: bim-me25 hioph-leu-betapy 7647: phhs-24thiaz-gly-betaheph 7648: ibhs-25oxaz-bala-csdap 7649: tolhs-me24oxaz-leu-zdap 7650: bhs-oxadiaz-bala-betah35dc40 7640: phhs-25thiaz-gly-betapym 7641: bim-42nmeim-ala-psdap 7642: bhs-24thioph-bala-beta35dbph 7643: tolhs-25oxaz-bala-betafph 7644: tolhs-25methiaz-gly-betaimid 45 7645: phhs -me25oxaz-bala-beta34meoph 7646: bim-me25 hioph-leu-betapy 7647: phhs-24thiaz-gly-betaheph 7648: ibhs-25oxaz-bala-csdap 7649: tolhs-me24oxaz-leu-zdap 7650: bhs-oxadiaz-bala-betah35dc
7651: bhs-24thioph-nmgly-beta3quin 5 7652: tolhs-25oxaz-bala-psdaptb7651: bhs-24thioph-nmgly-beta3quin 5 7652: tolhs-25oxaz-bala-psdaptb
7653: bhs-nme35pyr-gly-betaibph7653: bhs-nme35pyr-gly-betaibph
7654: bhs-oxadiaz-bala-betafluo7654: bras-oxadiaz-bala-betafluo
7655: dimethpym-25oxaz-bala-betapy7655: dimethpym-25oxaz-bala-betapy
7656: tolhs-nme35pyr-bala-betafu27656: tolhs-nme35pyr-bala-betafu2
7657: phhs-nme35pyr-bala-betatbuph7657: phhs-nme35pyr-bala-betatbuph
10 7658: bhs-25oxaz-bala-psdap10 7658: bras-25oxaz-bala-psdap
7659: bim-oxadiaz-gly-aspaba7659: bim-oxadiaz-gly-aspaba
7660 : tolhs-ithiadiaz-gly-betabdimo7660: tolhs-ithiadiaz-gly-betabdimo
7661: bhs-24thioph-bala-betafphe7661: bras-24thioph-bala-betafphe
7662: tolhs-25oxaz-gly-busu2be 15 7663: bim-35pyrazo-ala-zdap7662: tolhs-25oxaz-gly-busu2be 15 7663: bim-35pyrazo-ala-zdap
7664: impy-24thiaz-bala-busu2be7664: impy-24thiaz-bala-busu2be
7665: gua-24thiaz-gly-betatrif7665: gua-24thiaz-gly betatrif
7666: phhs-me25oxaz-gly-betadcph7666: phhs-me25oxaz-gly-betadcph
7667: phhs-me24thioph-leu-zdap 20 7668: phhs-24thioph-gly-betadcph7667: phhs-me24thioph-leu-zdap 20 7668: phhs-24thioph-gly-betadcph
7669 : tolhs-ithiadiaz-bala-betatos7669: tolhs-ithiadiaz-bala-betatos
7670: bhs-ithiadiaz-gly-betafphe7670: bhs-ithiadiaz-gly-betafphe
7671 : phhs-ithiadiaz-bala-betadcphtb7671: phhs-ithiadiaz-bala-betadcphtb
7672: bhs-24thioph-bala-betahbcph7672: bhs-24thioph-bala-betahbcph
7673: bhs-ithiadiaz-gly-zdapch7673: bhs-ithiadiaz-gly-zdapch
25 7674: bim-42nmeim-ala-zdap25 7674: bim-42nmeim-ala-zdap
7675: tolhs-25methiaz-gly-betadcphtb7675: tolhs-25methiaz-gly-betadcphtb
7676: tolhs-nme35pyr-gly-betafu37676: tolhs-nme35pyr-gly-betafu3
7677: bhs-24thiaz-phg-betapy7677: bhs-24thiaz-phg-betapy
7678: ibhs-ithiadiaz-gly-suabu 30 7679: dhpyrr-25oxaz-bala-betadcph7678: ibhs-ithiadiaz-gly-suabu 30 7679: dhpyrr-25oxaz-bala-betadcph
7680: ibhs-oxadiaz-gly-betapbiph7680: ibhs-oxadiaz-gly-betapbiph
7681 : ibhs-25oxaz-bala-betathiome7681: ibhs-25oxaz-bala-betathiome
7682: hts-24oxaz-gly-betapy7682: hts-24oxaz-gly-betapy
7683: tolhs-25oxaz-gly-psdapch 35 7684: phhs-25methiaz-gly-betal3bendi7683: tolhs-25oxaz-gly-psdapch 35 7684: phhs-25methiaz-gly-betal3bendi
7685: bim-25thiaz-bala-zdap7685: bim-25thiaz-bala-zdap
7686: gua-42pym-gly-betahdcph7686: gua-42pym-gly-betahdcph
7687: phhs-25oxaz-gly-betaanaphth7687: phhs-25oxaz-gly-betaanaphth
7688: phhs-ithiadiaz-gly-betathio37688: phhs-ithiadiaz-gly-betathio3
7689 : bhs-nme35pyr-gly-beta34meoph7689: bhs-nme35pyr-gly-beta34meoph
40 7690: bhs-25thiaz-gly-betafu340 7690: bhs-25thiaz-gly-betafu3
7691: bim-24thiaz-ala-betapy7691: bim-24thiaz-ala-betapy
7692: tolhs-ithiadiaz-gly-betabpy7692: tolhs-ithiadiaz-gly-betabpy
7693: ibhs-25thiaz-bala-beta4bph7693: ibhs-25thiaz-bala-beta4bph
7694: tolhs-nme35pyr-bala-betadmph 45 7695: ibhs-24thioph-gly-betathio37694: tolhs-nme35pyr-bala-betadmph 45 7695: ibhs-24thioph-gly-betathio3
7696: bhs-24thioph-gly-betainyl7696: bhs-24thioph-gly-betainyl
7697: ur-42 meim-gly-psdap 7698: phhs-25oxaz-bala-betacthioph 7699: bim-24thioph-bala-aspaba 7700: bim-me24oxaz-bala-betapy 7701: ibhs-nme35pyr-bala-betadmph 5 7702: ibhs-24thiaz-bala-betadcph 7703: tolhs-25oxaz-gly-betabdimo7697: ur-42 meim-gly-psdap 7698: phhs-25oxaz-bala-betacthioph 7699: bim-24thioph-bala-aspaba 7700: bim-me24oxaz-bala-betapy 7701: ibhs-nme35pyr-bala-betadmph 5 7702: ibhs-24thiaz-bala-betadch 7703: tol 25oxaz-gly-betabdimo
7704 : bhs-nme35pyr-gly-beta23meoph7704: bhs-nme35pyr-gly-beta23meoph
7705: bhs-nme35pyr-bala-betafu37705: bhs-nme35pyr-bala-betafu3
7706: cima-42pym-gly-betainyl7706: cima-42pym-gly-betainyl
7707 : tolhs-oxadiaz-bala-betadcphtb7707: tolhs-oxadiaz-bala-betadcphtb
1010
7708: 2py-me24thioph-ala-zdap7708: 2py-me24thioph-ala-zdap
7709: phhs-25oxaz-bala-betaet7709: phhs-25oxaz-bala-betaet
7710: ibhs-oxadiaz-gly-betambiph7710: ibhs-oxadiaz-gly-betambiph
7711: bhs-ithiadiaz-bala-betaet7711: bhs-ithiadiaz-bala-betet
7712: gua-2 oxaz-gly-betadcph 15 7713: tolhs-25methiaz-gly-betaph7712: gua-2 oxaz-gly-betadcph 15 7713: tolhs-25methiaz-gly-betaph
7714: bhs-25thiaz-gly-betacph7714: bhs-25thiaz-gly-betacph
7715: impy-25oxaz-bala-betaoxaz7715: impy-25oxaz-bala-betaoxaz
7716 : ibhs-oxadiaz-bala-beta35dbph7716: ibhs-oxadiaz-bala-beta35dbph
7717 : phhs-ithiadiaz-bala-beta34meoph 20 7718: 2py-35thioph-gly-psdap7717: phhs-ithiadiaz-bala-beta34meoph 20 7718: 2py-35thioph-gly-psdap
7719 : tolhs-nme35pyr-bala-betadcphtb7719: tolhs-nme35pyr-bala-betadcphtb
7720: dhim-52thiaz-gly-betainyl7720: dhim-52thiaz-gly-betainyl
7721 : bhs-25methiaz-nmgly-betathioph7721: bhs-25methiaz-nmgly-betathioph
7722 : tolhs-24thioph-gly-betaimid7722: tolhs-24thioph-gly-betaimide
7723: bhs-25methiaz-bala-betaheph7723: bhs-25methiaz-bala-betaheph
25 7724: phhs-nme35pyr-bala-betahdbph25 7724: phhs-nme35pyr-bala-betahdbph
7725: phhs-25thiaz-gly-psdap7725: phhs-25thiaz-gly-psdap
7726: bhs-ithiadiaz-gly-betadcph7726: bhs-ithiadiaz-gly-betadcph
7727: tolhs-nme35pyr-bala-betabpy7727: tolhs-nme35pyr-bala-betabpy
7728: ibhs-25thiaz-bala-psdaptb 30 7729: 2py-25thiaz-gly-aspbzla7728: ibhs-25thiaz-bala-psdaptb 30 7729: 2py-25thiaz-gly-aspbzla
7730: phhs-25oxaz-gly-betabph7730: phhs-25oxaz-gly-betabph
7731: phhs-25oxaz-gly-betamesu7731: phhs-25oxaz-gly-betamesu
7732: bhs-oxadiaz-ala-betabnaphth7732: bhs-oxadiaz-ala-betabnaphth
7733: bhs-nme35pyr-bala-betafbph 35 7734: tolhs-24thioph-bala-betadito7733: bhs-nme35pyr-bala-betafbph 35 7734: tolhs-24thioph-bala-betadito
7735: ibhs-25thiaz-bala-psdap7735: ibhs-25thiaz-bala-psdap
7736 : tolhs-25thiaz-bala-betabdimo7736: tolhs-25thiaz-bala-betabdimo
7737: bhs-25thiaz-gly-zdapch7737: bhs-25thiaz-gly-zdapch
7738: phhs-me25thiaz-bala-betapy7738: phhs-me25thiaz-bala-betapy
7739: phhs-24thiaz-gly-betapbiph7739: phhs-24thiaz-gly-betapbiph
40 7740 : tolhs-oxadiaz-bala-betaphethio40 7740: tolhs-oxadiaz-bala-betaphethio
7741: hs-26py-gly-betapy7741: hs-26py-gly-betapy
7742: bhs-24thioph-gly-aspibua7742: bhs-24thioph-gly-aspibua
7743: phhs-nme35pyr-bala-betabdimo7743: phhs-nme35pyr-bala-betabdimo
7744: gua-24thiaz-gly-betathio3 45 7745: bhs-25methiaz-gly-betabpy7744: gua-24thiaz-gly-betathio3 45 7745: bhs-25methiaz-gly-betabpy
7746: dhim-42pym-gly-psdap7746: dhim-42pym-gly-psdap
7747: ibhs-25thiaz-gly-asppha 7748: tolhs-nme35pyr-gly-betathiobe7747: ibhs-25thiaz-gly-asppha 7748: tolhs-nme35pyr-gly-betathiobe
7749: 2py-me24oxaz-leu-psdap7749: 2py-me24oxaz-leu-psdap
7750: phhs-25thiaz-bala-zdaptb7750: phhs-25thiaz-bala-zdaptb
7751: 2py-42pym-ala-betapy 5 7752: phhs-25methiaz-bala-betahdcph7751: 2py-42pym-ala-betapy 5 7752: phhs-25methiaz-bala-betahdcph
7753: phhs-25oxaz-gly-psdapee7753: phhs-25oxaz-gly-psdapee
7754: ibhs-24thiaz-gly-betambiph7754: ibhs-24thiaz-gly-betambiph
7755: phhs-oxadiaz-gly-zdap7755: phhs-oxadiaz-gly-zdap
7756: bhs-35thioph-leu-psdap7756: bhs-35thioph-leu-psdap
7757 : tolhs-ithiadiaz-gly-betathioph7757: tolhs-ithiadiaz-gly-betathioph
10 7758: bim-25fur-leu-zdap10 7758: bim-25fur-leu-zdap
7759: gua-24thiaz-gly-betadmph7759: gua-24thiaz-gly-betadmph
7760 : phhs-ithiadiaz-gly-betatrif7760: phhs-ithiadiaz-gly-betatrif
7761: gua-42pym-gly-betapy7761: gua-42pym-gly-betapy
7762: phhs-25oxaz-bala-betaol 15 7763: bim-oxadiaz-gly-zdap7762: phhs-25oxaz-bala-betaol 15 7763: bim-oxadiaz-gly-zdap
7764: ibhs-oxadiaz-gly-betainyl7764: ibhs-oxadiaz-gly-betainyl
7765: bhs-25methiaz-bala-betadbph7765: bras-25methiaz-bala-betadbph
7766: phhs-24thiaz-gly-betabdimo7766: phhs-24thiaz-gly-betabdimo
7767 : bhs-25thiaz-nmgly-beta23meoph 20 7768: bhs-25thiaz-gly-betathiome7767: bhs-25thiaz-nmgly-beta23meoph 20 7768: bhs-25thiaz-gly-betathiome
7769 : tolhs-me25thiaz-ala-betadcph7769: tolhs-me25thiaz-ala-betadcph
7770: bhs-me25oxaz-bala-psdap7770: bhs-me25oxaz-bala-psdap
7771: bhs-nme35pyr-bala-betadbph7771: bhs-nme35pyr-bala-betadbph
7772 : bhs-25methiaz-gly-betathioph7772: bhs-25methiaz-gly-betathioph
7773 : bhs-24thioph-nmgly-beta34dcph 25 7774 : ιbhs-25methιaz-bala-betadmoph7773: bhs-24thioph-nmgly-beta34dcph 25 7774: ιbhs-25methιaz-bala-betadmoph
7775: phhs-24thioph-bala-betaheph7775: phhs-24thioph-bala-betaheph
7776: bhs-25oxaz-bala-betabph7776: bras-25oxaz-bala-betabph
7777: bhs-oxadiaz-ala-betahmph7777: bhs-oxadiaz-ala-betahmph
7778: phhs-nme35pyr-bala-betaimid 30 7779: ibhs-oxadiaz-bala-betapym7778: phhs-nme35pyr-bala-betaimid 30 7779: ibhs-oxadiaz-bala-betapym
7780: ibhs-25thiaz-gly-betafphe7780: ibhs-25thiaz-gly-betafphe
7781: 2py-24thiaz-gly-psdap7781: 2py-24thiaz-gly-psdap
7782 : tolhs-24thiaz-gly-betathiome7782: tolhs-24thiaz-gly-betathioma
7783 : bhs-ithiadiaz-nmgly-betaoxaz 35 7784: thazep-24oxaz-gly-betapy7783: bhs-ithiadiaz-nmgly-betaoxaz 35 7784: thazep-24oxaz-gly-betapy
7785: phhs-oxadiaz-bala-psdap7785: phhs-oxadiaz-bala-psdap
7786: ibhs-25oxaz-gly-beta4bph7786: ibhs-25oxaz-gly-beta4bph
7787 : phhs-25thiaz-gly-betapyee7787: phhs-25thiaz-gly-betapyee
7788: bhs-35thioph-gly-betapy7788: bhs-35thioph-gly-betapy
7789: 2py-35fur-leu-psdap 407789: 2py-35fur-leu-psdap 40
7790: tolhs-24thιoph-gly-aspιbua7790: tolhs-24thιoph-gly-aspιbua
7791: tolhs-24thioph-bala-betaftrif7791: tolhs-24thioph-bala-betaftrif
7792: bhs-25methiaz-gly-betahc7792: bhs-25methiaz-gly-betahc
7793: tolhs-24thiaz-gly-psdapee7793: tolhs-24thiaz-gly-psdapee
7794: bim-24thiaz-gly-betapy7794: bim-24thiaz-gly-betapy
45 7795: tolhs-25thiaz-bala-betaibph45 7795: tolhs-25thiaz-bala-betaibph
7796 : tolhs-me24thiaz-leu-betadcph7796: tolhs-me24thiaz-leu-betadcph
7797 : 2py-me24oxaz-bala-beta34meoph 7798 : bhs-nme35pyr-nmgly-betal3bendi7797: 2py-me24oxaz-bala-beta34meoph 7798: bhs-nme35pyr-nmgly-betal3bendi
7799 : phhs-25oxaz-gly-betafphe7799: phhs-25oxaz-gly-betafphe
7800 : bhs-nme35pyr-bala-betahph7800: bhs-nme35pyr-bala-betahph
7801: impy-25thiaz-gly-zdap 5 7802: gua-24oxaz-gly-betafluo7801: impy-25thiaz-gly-zdap 5 7802: gua-24oxaz-gly-betafluo
7803: phhs-ithiadiaz-gly-betaheph7803: phhs-ithiadiaz-gly-betaheph
7804: bhs-42nmeim-leu-betadcph7804: bras-42nmeim-leu-betadcph
7805: phhs-nme35pyr-bala-busu2be7805: phhs-nme35pyr-bala-busu2be
7806: bim-thiadiaz-leu-psdap7806: bim-thiadiaz-leu-psdap
7807: dhim-52thiaz-ala-zdap7807: dhim-52thiaz-ala-zdap
10 7808: bhs-24thioph-gly-betahdbph10 7808: bhs-24thioph-gly-betahdbph
7809: nmhs-24oxaz-gly-betapy7809: nmhs-24oxaz-gly-betapy
7810: gua-42pym-gly-betahb7810: gua-42pym-gly-betahb
7811 : tolhs-ithiadiaz-gly-betathiome7811: tolhs-ithiadiaz-gly-betathiome
7812: 2py-24thioph-bala-aspbzla 15 7813: bhs-25oxaz-gly-betathiobe7812: 2py-24thioph-bala-aspbzla 15 7813: bhs-25oxaz-gly-betathiobe
7814: tolhs-me24oxaz-bala-psdap7814: tolhs-me24oxaz-bala-psdap
7815: bhs-24thioph-gly-betahmph7815: bhs-24thioph-gly-betahmph
7816: tolhs-nme35pyr-bala-csdap7816: tolhs-nme35pyr-bala-csdap
7817: ibhs-25thiaz-gly-betamesu 20 7818: phhs-24thiaz-bala-ibsdap7817: ibhs-25thiaz-gly-betamesu 20 7818: phhs-24thiaz-bala-ibsdap
7819: 2py-thiadiaz-gly-betadcph7819: 2py-thiadiaz-gly-betadcph
7820: 2py-42oxaz-ala-betapy7820: 2py-42oxaz-ala-betapy
7821: bhs-25thiaz-gly-psdapee7821: bhs-25thiaz-gly-psdapee
7822 : bim-oxadiaz-ala-betadcph7822: bim-oxadiaz-ala-betadcph
7823 : phhs-24thioph-bala-betadcphtb7823: phhs-24thioph-bala-betadcphtb
25 7824: tolhs-25thiaz-gly-betampy25 7824: tolhs-25thiaz-gly-betampy
7825: ibhs-24thiaz-gly-betapych7825: ibhs-24thiaz-gly-betapych
7826: phhs-24thioph-gly-betamesu7826: phhs-24thioph-gly-betamesu
7827: tolhs-me25thiaz-bala-psdap7827: tolhs-me25thiaz-bala-psdap
7828: bim-25oxaz-bala-betadcph 30 7829: bhs-nme35pyr-gly-zdapch7828: bim-25oxaz-bala-betadcph 30 7829: bhs-nme35pyr-gly-zdapch
7830 : ibhs-25methiaz-gly-betaphethioa7830: ibhs-25methiaz-gly-betaphethioa
7831: phhs-24thiaz-bala-aspaba7831: phhs-24thiaz-bala-aspaba
7832 : tolhs-24thioph-bala-betahdbph7832: tolhs-24thioph-bala-betahdbph
7833: bhs-me24thioph-leu-psdap 35 7834: phhs-25oxaz-gly-betathio37833: bhs-me24thioph-leu-psdap 35 7834: phhs-25oxaz-gly-betathio3
7835: bhs-24thiaz-bala-beta4bph7835: bhs-24thiaz-bala-beta4bph
7836: phhs-nme35pyr-gly-betatos7836: phhs-nme35pyr-gly-betatos
7837: ibhs-nme35pyr-bala-betaoxaz7837: ibhs-nme35pyr-bala-betaoxaz
7838 : tolhs-24thioph-bala-betahbcph7838: tolhs-24thioph-bala-betahbcph
7839: bhs-oxadiaz-gly-betahni7839: bhs-oxadiaz-gly-betahni
40 7840 : phhs-25oxaz-bala-betaphethioa40 7840: phhs-25oxaz-bala-betaphethioa
7841: 2py-24thioph-bala-asppha7841: 2py-24thioph-bala-asppha
7842 : tolhs-24thioph-gly-betaomebendi7842: tolhs-24thioph-gly-betaomebendi
7843 : tolhs-25oxaz-bala-betabediox7843: tolhs-25oxaz-bala-betabediox
7844: impy-24 hioph-bala-betamesu 45 7845: ibhs-24thiaz-bala-betathiome7844: impy-24 hioph-bala-betamesu 45 7845: ibhs-24thiaz-bala-betathiome
7846: 2py-42nmeim-ala-betapy7846: 2py-42nmeim-ala-betapy
7847 : ibhs-24thiaz-bala-betaphethio 7848 : phhs-24thioph-bala-betafbph7847: ibhs-24thiaz-bala-betaphethio 7848: phhs-24thioph-bala-betafbph
7849: phhs-me25thioph-ala-psdap7849: phhs-me25thioph-ala-psdap
7850: bhs-nme35pyr-gly-betamethi7850: bhs-nme35pyr-gly-betamethi
7851 : bim-me25thioph-bala-beta34meoph 5 7852: bhs-24thioph-gly-betapyr7851: bim-me25thioph-bala-beta34meoph 5 7852: bhs-24thioph-gly-betapyr
7853: ibhs-oxadiaz-gly-betaoxaz7853: ibhs-oxadiaz-gly-betaoxaz
7854: bhs-me24thioph-gly-betaph7854: bhs-me24thioph-gly-betaph
7855: bhs-53pyrazo-ala-psdap7855: bhs-53pyrazo-ala-psdap
7856 : phhs-oxadiaz-bala-betabdimo7856: phhs-oxadiaz-bala-betabdimo
7857: bhs-24thiaz-gly-betadtrif7857: bhs-24thiaz-gly-betadtrif
10 7858: bim-25oxaz-leu-betadcph10 7858: bim-25oxaz-leu-betadcph
7859: ibhs-ithiadiaz-gly-betapym7859: ibhs-ithiadiaz-gly-betapym
7860: bhs-nme35pyr-bala-beta3quin7860: bhs-nme35pyr-bala-beta3quin
7861 : bhs-ithiadiaz-bala-betabdimo7861: bhs-ithiadiaz-bala-betabdimo
7862: ibhs-oxadiaz-bala-betahmph 15 7863: tolhs-25methiaz-gly-betahmo7862: ibhs-oxadiaz-bala-betahmph 15 7863: tolhs-25methiaz-gly-betahmo
7864 : ibhs-25methiaz-gly-betamethi7864: ibhs-25methiaz-gly-betamethi
7865: ibhs-25thiaz-gly-aspaba7865: ibhs-25thiaz-gly-aspaba
7866 : bhs-oxadiaz-bala-betadcphch7866: bras-oxadiaz-bala-betadcphch
7867 : ibhs-ithiadiaz-bala-betapych 20 7868: bhs-24thiaz-gly-betabmph7867: ibhs-ithiadiaz-bala-betapych 20 7868: bhs-24thiaz-gly-betabmph
7869: ibhs-ithiadiaz-gly-csdap7869: ibhs-ithiadiaz-gly-csdap
7870: bhs-25oxaz-ala-betameph7870: bras-25oxaz-ala-betameph
7871: bhs-25oxaz-gly-psdapch7871: bhs-25oxaz-gly-psdapch
7872: bhs-25thiaz-bala-beta35dbph7872: bhs-25thiaz-bala-beta35dbph
7873: bim-nme35pyr-bala-betadcph7873: bim-nme35pyr-bala-betadcph
25 7874 -. phhs-oxadiaz-bala-betadcph25 7874 -. phhs-oxadiaz-bala-betadcph
7875: bim-24oxaz-leu-zdap7875: bim-24oxaz-leu-zdap
7876: bhs-ithiadiaz-gly-betaphethioa7876: bhs-ithiadiaz-gly-betaphethioa
7877: bhs-24thiaz-gly-betathio37877: bhs-24thiaz-gly-betathio3
7878: tolhs-24thiaz-bala-betampy 30 7879: bhs-24thiaz-gly-betadito7878: tolhs-24thiaz-bala-betampy 30 7879: bhs-24thiaz-gly-betadito
7880: bhs-me24thioph-bala-betaph7880: bhs-me24thioph-bala-betaph
7881: 2py-24oxaz-ala-betainyl7881: 2py-24oxaz-ala-betainyl
7882: bhs-nme35pyr-bala-beta thioph7882: bhs-nme35pyr-bala-beta thioph
7883 : phhs-25methiaz-bala-betathio3 35 7884: bhs-25thiaz-gly-betabph7883: phhs-25methiaz-bala-betathio3 35 7884: bhs-25thiaz-gly-betabph
7885: tolhs-25thiaz-gly-betadcph7885: tolhs-25thiaz-gly-betadcph
7886: ibhs-24thioph-gly-betaimid7886: ibhs-24thioph-gly-betaimide
7887: ibhs-24thiaz-gly-betadcph7887: ibhs-24thiaz-gly-betadcph
7888: ibhs-ithiadiaz-gly-psdapch7888: ibhs-ithiadiaz-gly-psdapch
7889: tolhs-me25thiaz-ala-betaph7889: tolhs-me25thiaz-ala-betaph
40 7890: thazep-42pym-gly-betadcph40 7890: thazep-42pym-gly-betadcph
7891: bhs-25thiaz-bala-betaol7891: bhs-25thiaz-bala-betaol
7892: phhs-ithiadiaz-gly-psdapee7892: phhs-ithiadiaz-gly-psdapee
7893: bhs-24thioph-ala-betaipro7893: bhs-24thioph-ala-betaipro
7894: bhs-24thioph-gly-betaftrif 45 7895: bhs-ithiadiaz-bala-betapych7894: bhs-24thioph-gly-betaftrif 45 7895: bhs-ithiadiaz-bala-betapych
7896: phhs-24thiaz-gly-betaamibe7896: phhs-24thiaz-gly-betaamibe
7897 : bhs-nme35pyr-gly-betaphethioa 7898 : bim-25methiaz-gly-betaanaphth7897: bhs-nme35pyr-gly-betaphethioa 7898: bim-25methiaz-gly-betaanaphth
7899: bim-thiadiaz-gly-zdap7899: bim-thiadiaz-gly-zdap
7900: ibhs-25methiaz-gly-asppha7900: ibhs-25methiaz-gly-asppha
7901 : tolhs-24thiaz-bala-betaphethio 5 7902: ibhs-24thiaz-bala-psdapch7901: tolhs-24thiaz-bala-betaphethio 5 7902: ibhs-24thiaz-bala-psdapch
7903 : tolhs-25thiaz-gly-betaanaphth7903: tolhs-25thiaz-gly-betaanaphth
7904 : bhs-25methiaz-bala-betadcph.ee7904: bhs-25methiaz-bala-betadcph.ee
7905 : tolhs-me24oxaz-bala-betadcph7905: tolhs-me24oxaz-bala-betadcph
7906: bhs-25methiaz-bala-psdap7906: bras-25methiaz-bala-psdap
7907: tolhs-nme35pyr-bala-betafph7907: tolhs-nme35pyr-bala-betafph
10 7908: ibhs-oxadiaz-gly-zdaptb10 7908: ibhs-oxadiaz-gly-zdaptb
7909: bhs-oxadiaz-ala-betabpy7909: bhs-oxadiaz-ala-betabpy
7910: bhs-nme35pyr-gly-betathiome7910: bhs-nme35pyr-gly-betathioma
7911: 2py-42oxaz-gly-psdap7911: 2py-42oxaz-gly-psdap
7912: bim-me24oxaz-gly-betapy 15 7913: tolhs-25oxaz-bala-betahb7912: bim-me24oxaz-gly-betapy 15 7913: tolhs-25oxaz-bala-betahb
7914 : ibhs-ithiadiaz-gly-betah35dc7914: ibhs-ithiadiaz-gly-betah35dc
7915: phhs-25methiaz-bala-betapym7915: phhs-25methiaz-bala-betapym
7916: bhs-ithiadiaz-gly-busu2be7916: bhs-ithiadiaz-gly-busu2be
7917 : tolhs-ithiadiaz-bala-betacph 20 7918: tolhs-24thioph-bala-zdapee7917: tolhs-ithiadiaz-bala-betacph 20 7918: tolhs-24thioph-bala-zdapee
7919: bhs-me25thiaz-leu-psdap7919: bhs-me25thiaz-leu-psdap
7920: gua-24thiaz-gly-betabnaphth7920: gua-24thiaz-gly-betabnaphth
7921: bhs-oxadiaz-gly-betaipr7921: bhs-oxadiaz-gly-betaipr
7922 : bhs-me25thiaz-bala-beta34meoph7922: bhs-me25thiaz-bala-beta34meoph
7923 : bhs-25thiaz-bala-betamethioph 257923: bhs-25thiaz-bala-betamethioph 25
7924 : tolhs-24thiaz-bala-betadito7924: tolhs-24thiaz-bala-betadito
7925 : ibhs-ithiadiaz-bala-betacbph7925: ibhs-ithiadiaz-bala-betacbph
7926: phhs-24thiaz-gly-betafbph7926: phhs-24thiaz-gly-betafbph
7927: phhs-24thioph-gly-betacph7927: phhs-24thioph-gly-betacph
7928: phhs-25methiaz-bala-betainy1 30 7929: ibhs-nme35pyr-gly-betabthioph7928: phhs-25methiaz-bala-betainy1 30 7929: ibhs-nme35pyr-gly-betabthioph
7930: tolhs-24thiaz-bala-betahph7930: tolhs-24thiaz-bala-betahph
7931: tolhs-25oxaz-gly-betahcbph7931: tolhs-25oxaz-gly-betahcbph
7932 : tolhs-me24oxaz-bala-beta34meoph7932: tolhs-me24oxaz-bala-beta34meoph
7933: tolhs-me25oxaz-leu-betaph 35 7934: bhs-nme35pyr-gly-betafu27933: tolhs-me25oxaz-leu-betaph 35 7934: bhs-nme35pyr-gly-betafu2
7935 : bhs-me25oxaz-gly-beta34meoph7935: bhs-me25oxaz-gly-beta34meoph
7936: tolhs-25thiaz-bala-betapyee7936: tolhs-25thiaz-bala-betapyee
7937 : ibhs-nme35pyr-bala-betaanaphth7937: ibhs-nme35pyr-bala-betaanaphth
7938: bhs-oxadiaz-ala-betathio37938: bhs-oxadiaz-ala-betathio3
7939: 2py-25fur-ala-betapy7939: 2py-25fur-ala-betapy
40 7940: tolhs-25oxaz-bala-csdap40 7940: tolhs-25oxaz-bala-csdap
7941 : tolhs-nme35pyr-bala-aspibua7941: tolhs-nme35pyr-bala-aspibua
7942 : 4pmhs-25methiaz-bala-betameph7942: 4 pmhs-25methiaz-bala-betameph
7943 : bhs-nme35pyr-ala-betabnaphth7943: bhs-nme35pyr-ala-betabnaphth
7944: phhs-24thiaz-gly-betabπrph 45 7945: tolhs-24thiaz-gly-betaoxaz7944: phhs-24thiaz-gly-betabπrph 45 7945: tolhs-24thiaz-gly-betaoxaz
7946 : ibhs-ithiadiaz-bala-betambiph7946: ibhs-ithiadiaz-bala-betambiph
7947 : impy-25methiaz-bala-betah35dc 7948: tolhs-25oxaz-gly-betaet7947: impy-25methiaz-bala-betah35dc 7948: tolhs-25oxaz-gly-betaet
7949: phhs-oxadiaz-bala-betampy7949: phhs-oxadiaz-bala-betampy
7950: phhs-ithiadiaz-gly-betambiph7950: phhs-ithiadiaz-gly-betambiph
7951: bhs-nme35pyr-gly-betapytb 5 7952: phhs-ithiadiaz-bala-betabpy7951: bhs-nme35pyr-gly-betapytb 5 7952: phhs-ithiadiaz-bala-betabpy
7953: bim-25thioph-leu-zdap7953: bim-25thioph-leu-zdap
7954: bhs-24thiaz-ala-betafphe7954: bhs-24thiaz-ala-betafphe
7955: ibhs-nme35pyr-bala-betafu27955: ibhs-nme35pyr-bala-betafu2
7956: bhs-24thiaz-bala-zdapee7956: bras-24thiaz-bala-zdapee
7957 : phhs-24thiaz-bala-betacthioph7957: phhs-24thiaz-bala-betacthioph
10 7958: bim-53pyrazo-leu-zdap10 7958: bim-53pyrazo-leu-zdap
7959: ibhs-24thiaz-bala-zdapee7959: ibhs-24thiaz-bala-zdapee
7960: bim-me25thioph-gly-zdap7960: bim-me25thioph-gly-zdap
7961 : ibhs-oxadiaz-bala-betacthioph7961: ibhs-oxadiaz-bala-betacthioph
7962 : tolhs-me25thioph-bala-psdap 15 7963: phhs-25thiaz-gly-betafu37962: tolhs-me25thioph-bala-psdap 15 7963: phhs-25thiaz-gly-betafu3
7964: ibhs-24thiaz-bala-betabenfu7964: ibhs-24thiaz-bala-betabenfu
7965: tolhs-25thiaz-gly-betacbph7965: tolhs-25thiaz-gly-betacbph
7966: bhs-24thiaz-gly-betafbph7966: bhs-24thiaz-gly-betafbph
7967: bim-35fur-leu-betadcph 20 7968: bim-25oxaz-bala-betahph7967: bim-35fur-leu-betadcph 20 7968: bim-25oxaz-bala-betahph
7969 : phhs-24thiaz-gly-beta34dcph7969: phhs-24thiaz-gly-beta34dcph
7970: ibhs-nme35pyr-gly-beta23meoph7970: ibhs-nme35pyr-gly-beta23meoph
7971 : phhs-24thiaz-bala-betamethioph7971: phhs-24thiaz-bala-betamethioph
7972: ibhs-25thiaz-gly-beta3quin7972: ibhs-25thiaz-gly-beta3quin
7973: bim-25thioph-leu-psdap7973: bim-25thioph-leu-psdap
25 7974: bhs-25thiaz-gly-psdaptb25 7974: bhs-25thiaz-gly-psdaptb
7975: bhs-ithiadiaz-bala-betambiph7975: bhs-ithiadiaz-bala-betambiph
7976 : bhs-24thiaz-bala-betabthioph7976: bhs-24thiaz-bala-betabthioph
7977 : bhs-24thiaz-gly-beta34meoph7977: bhs-24thiaz-gly-beta34meoph
7978: bhs-24thioph-bala-betambiph 30 7979: bhs-ithiadiaz-ala-psdap7978: bhs-24thioph-bala-betambiph 30 7979: bhs-ithiadiaz-ala-psdap
7980: phhs-25thiaz-gly-betapych7980: phhs-25thiaz-gly-betapych
7981: bhs-oxadiaz-bala-betaph7981: bras-oxadiaz-bala-betaph
7982: 2py-42oxaz-bala-zdap7982: 2py-42oxaz-bala-zdap
7983: bhs-oxadiaz-gly-betadcphch 35 7984: bhs-25thiaz-gly-betabmph7983: bhs-oxadiaz-gly-betadcphch 35 7984: bhs-25thiaz-gly-betabmph
7985: bhs-25methiaz-gly-betafu37985: bhs-25methiaz-gly-betafu3
7986: bhs~nme35pyr-gly-betahmofu7986: bhs ~ nme35pyr-gly-betahmofu
7987: ibhs-oxadiaz-bala-psdap7987: ibhs-oxadiaz-bala-psdap
7988 : 2py-me24thioph-ala-beta34meoph7988: 2py-me24thioph-ala-beta34meoph
7989 : 2py-nme35pyr-bala-betadcph7989: 2py-nme35pyr-bala-betadcph
40 7990 : phhs-24thioph-bala-betathio340 7990: phhs-24thioph-bala-betathio3
7991: 2py-35thioph-ala-betadcph7991: 2py-35thioph-ala-betadcph
7992: phhs-24thioph-gly-betahcbph7992: phhs-24thioph-gly-betahcbph
7993: 2py-35fur-leu-betadcph7993: 2py-35fur-leu-betadcph
7994: ibhs-oxadiaz-bala-betadmph 45 7995: bhs-nme35pyr-gly-betaph7994: ibhs-oxadiaz-bala-betadmph 45 7995: bhs-nme35pyr-gly-betaph
7996: ibhs-oxadiaz-bala-betapytb7996: ibhs-oxadiaz-bala-betapytb
7997: phhs-25thiaz-gly-zdap 7998: impy-25oxaz-gly-betahdbph 7999: bhs-me25oxaz-bala-betadcph 8000: bim-25fur-gly-zdap 8001: bhs-25oxaz-ala-betaipro 8002: bhs-24thioph-nmgly-betahmph 8003: tolhs-nme35pyr-gly-betamethi 8004: bhs-me25thiaz-ala-psdap 8005 : gua-24thiaz-gly-betaphethioa 8006: birri725methiaz-leu-betadcph 8007: ibhs-ithiadiaz-bala-csdap7997: phhs-25thiaz-gly-zdap 7998: impy-25oxaz-gly-betahdbph 7999: bhs-me25oxaz-bala-betadcph 8000: bim-25fur-gly-zdap 8001: bhs-25oxaz-ala-betaipro 8002: bhs-24thioph-nmgly-betahmph 8003: tolpyrs-n -gly-betamethi 8004: bhs-me25thiaz-ala-psdap 8005: gua-24thiaz-gly-betaphethioa 8006: birri 7 25methiaz-leu-betadcph 8007: ibhs-ithiadiaz-bala-csdap
10 8008: phhs-25oxaz-gly-aspaba 8009 : tolhs-oxadiaz-gly-betathiome 8010: phhs-24thioph-gly-psdapee 8011: phhs-nme35pyr-gly-psdap 8012: bhs-25oxaz-nmgly-betameph10 8008: phhs-25oxaz-gly-aspaba 8009: tolhs-oxadiaz-gly-betathiome 8010: phhs-24thioph-gly-psdapee 8011: phhs-nme35pyr-gly-psdap 8012: bhs-25oxaz-nmgly-betameph
15 8013: tolhs-oxadiaz-gly-beta23meoph 8014 : ibhs-24thiaz-bala-betathioph 8015: tolhs-24thiaz-gly-betaet 8016: bhs-25oxaz-ala-betacthioph 8017: tolhs-oxadiaz-gly-betahmofu15 8013: tolhs-oxadiaz-gly-beta23meoph 8014: ibhs-24thiaz-bala-betathioph 8015: tolhs-24thiaz-gly-betaet 8016: bhs-25oxaz-ala-betacthioph 8017: tolhs-oxadiaz-gly-betahmofu
20 8018: phhs-24thioph-gly-betaet 8019: ibhs-25thiaz-bala-betabph 8020: tolhs-24thioph-bala-betampy 8021: bhs-25oxaz-gly-betahni 8022: bhs-25oxaz-gly-betahmofu 8023: bhs-me25thiaz-ala-betadcph20 8018: phhs-24thioph-gly-betet 8019: ibhs-25thiaz-bala-betabph 8020: tolhs-24thioph-bala-betampy 8021: bhs-25oxaz-gly-betahni 8022: bhs-25oxaz-gly-betahmofu 8023: bhs- me25thiaz-ala-betadcph
25 8024 : phhs-24thioph-bala-beta35dbph 8025: dhim-42pym-ala-psdap 8026: 2py-24thioph-gly-betatbuph 8027: bhs-oxadiaz-ala-betadcph 8028: 2py-35thioph-leu-zdap25 8024: phhs-24thioph-bala-beta35dbph 8025: dhim-42pym-ala-psdap 8026: 2py-24thioph-gly-betatbuph 8027: bhs-oxadiaz-ala-betadcph 8028: 2py-35thioph-leu-zdap
30 8029: phhs-oxadiaz-gly-betaimid 8030: phhs-nme35pyr-gly-betacph 8031: ibhs-nme35pyr-bala-zdap 8032: gua-26py-gly-betadmph 8033: phhs-25thiaz-gly-betaoxope30 8029: phhs-oxadiaz-gly-betaimide 8030: phhs-nme35pyr-gly-betacph 8031: ibhs-nme35pyr-bala-zdap 8032: gua-26py-gly-betadmph 8033: phhs-25thiaz-gly-betaoxope
35 8034: ibhs-oxadiaz-gly-betaamibe 8035: phhs-24thioph-gly-betapyee 8036: 2py-35thioph-gly-betapy 8037: bhs-35fur-ala-betapy 8038: bhs-24thiaz-nmgly-betamesu 8039: phhs-nme35pyr-gly-betaanaphth35 8034: ibhs-oxadiaz-gly-betaamibe 8035: phhs-24thioph-gly-betapyee 8036: 2py-35thioph-gly-betapy 8037: bhs-35fur-ala-betapy 8038: bhs-24thiaz-nmgly-betamesu 8039: phhs- nme35pyr-gly-betaanaphth
40 8040: bgua-42pym-gly-betainyl 8041: ibhs-24thiaz-bala-betafphe 8042: bhs-25thiaz-ala-betathio3 8043 : tolhs-24thiaz-bala-betacthioph 8044 : bhs-25fur-leu-betapy40 8040: bgua-42pym-gly-betainyl 8041: ibhs-24thiaz-bala-betafphe 8042: bhs-25thiaz-ala-betathio3 8043: tolhs-24thiaz-bala-betacthioph 8044: bhs-25fur-leu-betapy
45 8045: phhs-24thiaz-gly-betafu3 8046: phhs-24thiaz-gly-betahdcph 8047: tolhs-25thiaz-gly-aspibua 8048: phhs-25oxaz-bala-betapyee45 8045: phhs-24thiaz-gly-betafu3 8046: phhs-24thiaz-gly-betahdcph 8047: tolhs-25thiaz-gly-aspibua 8048: phhs-25oxaz-bala-betapyee
8049: ibhs-oxadiaz-gly-aspaba8049: ibhs-oxadiaz-gly-aspaba
8050: phhs-25methiaz-bala-betafbph8050: phhs-25methiaz-bala-betafbph
8051: bhs-25oxaz-nmgly-betadito 5 8052: bhs-oxadiaz-bala-betapyee8051: bhs-25oxaz-nmgly-betadito 5 8052: bhs-oxadiaz-bala-betapyee
8053: agua-25oxaz-bala-betameph8053: agua-25oxaz-bala-betameph
8054 : bim-me25thioph-bala-betadcph8054: bim-me25thioph-bala-betadcph
8055: tolhs-24thiaz-bala-betahb8055: tolhs-24thiaz-bala-betahb
8056: tolhs-me24thiaz-gly-psdap8056: tolhs-me24thiaz-gly-psdap
8057 : bhs-24thiaz-bala-betaphethioa8057: bhs-24thiaz-bala-betaphethioa
10 8058: 2py-25thiaz-leu-zdap10 8058: 2py-25thiaz-leu-zdap
8059: ibhs-oxadiaz-gly-betah35dc8059: ibhs-oxadiaz-gly-betah35dc
8060: tolhs-24thiaz-gly-beta4bph8060: tolhs-24thiaz-gly-beta4bph
8061: bhs-25methiaz-gly-betaipr8061: bhs-25methiaz-gly-betaipr
8062 : tolhs-ithiadiaz-gly-betaibph 15 8063: dhim-23thioph-gly-betameph8062: tolhs-ithiadiaz-gly-betaibph 15 8063: dhim-23thioph-gly-betameph
8064: bhs-24thioph-bala-zdaptb8064: bhs-24thioph-bala-zdaptb
8065: ibhs-25oxaz-gly-betaibph8065: ibhs-25oxaz-gly-betaibph
8066 : bhs-oxadiaz-nmgly-betacthioph8066: bhs-oxadiaz-nmgly-betacthioph
8067: bim-me25thioph-gly-betapy 20 8068: bhs-24thioph-gly-betahbcph8067: bim-me25thioph-gly-betapy 20 8068: bhs-24thioph-gly-betahbcph
8069: bim-me24oxaz-gly-betaph8069: bim-me24oxaz-gly-betaph
8070: impy-25oxaz-bala-betahmo8070: impy-25oxaz-bala-betahmo
8071: ibhs-25methiaz-gly-beta23meoph8071: ibhs-25methiaz-gly-beta23meoph
8072 : 2py-ithiadiaz-bala-psdap8072: 2py-ithiadiaz-bala-psdap
8073: phhs-24thiaz-gly-betatos8073: phhs-24thiaz-gly-betatos
25 8074: bim-me24oxaz-leu-betaph25 8074: bim-me24oxaz-leu-betaph
8075: 2py-26py-gly-psdap8075: 2py-26py-gly-psdap
8076: bhs-24thiaz-ala-betathio38076: bhs-24thiaz-ala-betathio3
8077: bhs-25thiaz-bala-betatrif8077: bras-25thiaz-bala-betatrif
8078: bim-24thiaz-gly-aspibua 30 8079: phhs-oxadiaz-bala-betathiome8078: bim-24thiaz-gly-aspibua 30 8079: phhs-oxadiaz-bala-betathiome
8080 : tolhs-24thioph-gly-betaibph8080: tolhs-24thioph-gly-betaibph
8081 : phhs-24thiaz-bala-betaphethio8081: phhs-24thiaz-bala-betaphethio
8082 : tolhs-ithiadiaz-bala-betaph8082: tolhs-ithiadiaz-bala-betaph
8083 : bhs-24thiaz-bala-betathiome 35 8084: bhs-me25thioph-gly-zdap8083: bhs-24thiaz-bala-betathiome 35 8084: bhs-me25thioph-gly-zdap
8085: phhs-nme35pyr-gly-betathiome8085: phhs-nme35pyr-gly-betathiome
8086: tolhs-ithiadiaz-gly-zdapee8086: tolhs-ithiadiaz-gly-zdapee
8087 : phhs-25oχaz-bala-betaamibe8087: phhs-25oχaz-bala-betaamibe
8088: bim-24oxaz-bala-psdap8088: bim-24oxaz-bala-psdap
8089: phhs-25oxaz-bala-aspbzla8089: phhs-25oxaz-bala-aspbzla
40 8090: bim-42oxaz-gly-zdap40 8090: bim-42oxaz-gly-zdap
8091: ibhs-25thiaz-bala-betatos8091: ibhs-25thiaz-bala-betatos
8092: ibhs-oxadiaz-bala-aspaba8092: ibhs-oxadiaz-bala-aspaba
8093: phhs-nme35pyr-g1y-betadcph8093: phhs-nme35pyr-g1y-betadcph
8094: gua-24thiaz-gly-beta3quin 45 8095: 2py-25oxaz-gly-betathiobe8094: gua-24thiaz-gly-beta3quin 45 8095: 2py-25oxaz-gly-betathiobe
8096 : tolhs-25methiaz-bala-betabnaphth8096: tolhs-25methiaz-bala-betabnaphth
8097: bhs-25oxaz-ala-betacph 8098 : bhs-nme35pyr-bala-betahcbph8097: bhs-25oxaz-ala-betacph 8098: bhs-nme35pyr-bala-betahcbph
8099: bim-me24thioph-ala-betaph8099: bim-me24thioph-ala-betaph
8100: ibhs-25methiaz-bala-ibsdap8100: ibhs-25methiaz-bala-ibsdap
8101: bhs-25methiaz-leu-zdap 5 8102: bhs-25thiaz-ala-betadhbfu8101: bhs-25methiaz-leu-zdap 5 8102: bhs-25thiaz-ala-betadhbfu
8103: bim-42oxaz-gly-psdap8103: bim-42oxaz-gly-psdap
8104: bhs-25thiaz-gly-betabiph8104: bhs-25thiaz-gly-betabiph
8105: gua-25thioph-gly-betaipr8105: gua-25thioph-gly-betaipr
8106: phhs-24thioph-gly-betapych8106: phhs-24thioph-gly-betapych
8107: bhs-25oxaz-gly-beta23meoph8107: bhs-25oxaz-gly-beta23meoph
10 8108: tolhs-24thioph-bala-asppha10 8108: tolhs-24thioph-bala-asppha
8109: bhs-24thiaz-gly-betaipro8109: bhs-24thiaz-gly-betaipro
8110 : tolhs-ithiadiaz-bala-betahdcph8110: tolhs-ithiadiaz-bala-betahdcph
8111: bim-24thiaz-ala-zdap8111: bim-24thiaz-ala-zdap
8112 : tolhs-25thiaz-bala-beta34meoph 15 8113: bhs-ithiadiaz-gly-betaipro8112: tolhs-25thiaz-bala-beta34meoph 15 8113: bhs-ithiadiaz-gly-betaipro
8114: tolhs-25thiaz-gly-betapych8114: tolhs-25thiaz-gly-betapych
8115: tolhs-24thioph-bala-aspibua8115: tolhs-24thioph-bala-aspibua
8116: bhs-nme35pyr-gly-betafbph8116: bhs-nme35pyr-gly-betafbph
8117: dhim-52thiaz-ala-betadcph 20 8118: 2py-35fur-ala-betadcph8117: dhim-52thiaz-ala-betadcph 20 8118: 2py-35fur-ala-betadcph
8119: phhs-25thiaz-bala-zdap8119: phhs-25thiaz-bala-zdap
8120: 2pmhs-25thiaz-gly-betahbcph8120: 2 pmhs-25thiaz-gly-betahbcph
8121 : bhs-25thiaz-bala-betahph8121: bras-25thiaz-bala-betahph
8122 : bhs-oxadiaz-bala-betathiobe8122: bras-oxadiaz-bala-betathiobe
8123 : bhs-25methiaz-ala-betathioph8123: bhs-25methiaz-ala-betathioph
2525
8124: tolhs-25oxaz-gly-aspaba8124: tolhs-25oxaz-gly-aspaba
8125: 2py-24thiaz-gly-beta35dbph8125: 2py-24thiaz-gly-beta35dbph
8126: ibhs-ithiadiaz-gly-betahc8126: ibhs-ithiadiaz-gly-betahc
8127: bhs-oxadiaz-bala-betabdimo8127: bras-oxadiaz-bala-betabdimo
8128: phhs-25oxaz-bala-betaphethio 30 8129: bhs-25oxaz-ala-betal3bendi8128: phhs-25oxaz-bala-betaphethio 30 8129: bhs-25oxaz-ala-betal3bendi
8130 : phhs-ithiadiaz-bala-beta23meoph8130: phhs-ithiadiaz-bala-beta23meoph
8131: bhs-25methiaz-gly-betafph8131: bhs-25methiaz-gly-betafph
8132 : tolhs-24thiaz-gly-betaol8132: tolhs-24thiaz-gly-betaol
8133 : tolhs-oxadiaz-gly-betaipro 35 8134: tolhs-25methiaz-gly-aspbzla8133: tolhs-oxadiaz-gly-betaipro 35 8134: tolhs-25methiaz-gly-aspbzla
8135 : ibhs-oxadiaz-gly-betaanaphth8135: ibhs-oxadiaz-gly-betaanaphth
8136 : tolhs-oxadiaz-bala-betaoxope8136: tolhs-oxadiaz-bala-betaoxope
8137 : bhs-25methiaz-nmgly-betacthioph8137: bhs-25methiaz-nmgly-betacthioph
8138: 2pmhs-25thiaz-gly-betaph8138: 2 pmhs-25thiaz-gly-betaph
8139: bhs-25oxaz-gly-betadcphch8139: bhs-25oxaz-gly-betadcphch
40 8140: bim-25oxaz-bala-betabmph40 8140: bim-25oxaz-bala-betabmph
8141: bhs-nme35pyr-gly-betafphe8141: bhs-nme35pyr-gly-betafphe
8142: bhs-ithiadiaz-bala-betatos8142: bras-ithiadiaz-bala-betatos
8143: phhs-24thiaz-gly-betamethi8143: phhs-24thiaz-gly-betamethi
8144: thpym-24oxaz-gly-zdap 45 8145: tolhs-me25thiaz-bala-beta34meoph8144: thpym-24oxaz-gly-zdap 45 8145: tolhs-me25thiaz-bala-beta34meoph
8146 : tolhs-nme35pyr-bala-betaimid8146: tolhs-nme35pyr-bala-betaimid
8147: bhs-nme35pyr-ala-betainyl 8148: bhs-25oxaz-gly-betatbuph8147: bhs-nme35pyr-ala-betainyl 8148: bhs-25oxaz-gly-betatbuph
8149: 2py-42pym-ala-betadcph8149: 2py-42pym-ala-betadcph
8150: tolhs-24thioph-gly-betafph8150: tolhs-24thioph-gly-betafph
8151: bim-me25oxaz-bala-betapy8151: bim-me25oxaz-bala-betapy
5 8152: bim-25methiaz-bala-aspbzla5 8152: bim-25methiaz-bala-aspbzla
8153: 2py-me25thiaz-ala-zdap8153: 2py-me25thiaz-ala-zdap
8154: tolhs-25thiaz-gly-psdaptb8154: tolhs-25thiaz-gly-psdaptb
8155: 2py-52thiaz-ala-betadcph8155: 2py-52thiaz-ala-betadcph
8156: bhs-25oxaz-bala-betah35dc8156: bras-25oxaz-bala-betah35dc
8157: gua-24oxaz-gly-betaipro8157: gua-24oxaz-gly-betaipro
8158: tolhs-me25thioph-ala-psdap8158: tolhs-me25thioph-ala-psdap
8159: gua-24thiaz-gly-betamethi8159: gua-24thiaz-gly-betamethi
8160: bhs-nme35pyr-leu-betadcph8160: bhs-nme35pyr-leu-betadcph
8161: bim-oxadiaz-gly-betapy8161: bim-oxadiaz-gly-betapy
8162: bhs-35fur-ala-psdap8162: bhs-35fur-ala-psdap
15 8163: bhs-25methiaz-gly-betapy15 8163: bhs-25methiaz-gly-betapy
8164 : ibhs-24thiaz-bala-betal3bendi8164: ibhs-24thiaz-bala-betal3bendi
8165 : tolhs-24thiaz-bala-beta3quin8165: tolhs-24thiaz-bala-beta3quin
8166 : bhs-ithiadiaz-bala-betatrif8166: bras-ithiadiaz-bala-betatrif
8167: bhs-ithiadiaz-gly-betahmph8167: bhs-ithiadiaz-gly-betahmph
20 8168: tolhs-ithiadiaz-gly-betaheph20 8168: tolhs-ithiadiaz-gly-betaheph
8169: tolhs-24thioph-gly-betampy8169: tolhs-24thioph-gly-betampy
8170 : tolhs-25oxaz-gly-betathiome8170: tolhs-25oxaz-gly-betathioma
8171: ibhs-nme35pyr-gly-betahdcph8171: ibhs-nme35pyr-gly-betahdcph
8172 : ibhs-oxadiaz-bala-betabediox8172: ibhs-oxadiaz-bala-betabediox
8173: phhs-25methiaz-bala-betadhbfu 258173: phhs-25methiaz-bala-betadhbfu 25
8174 : bhs-25methiaz-gly-betabnaphth8174: bhs-25methiaz-gly-betabnaphth
8175: bhs-ithiadiaz-bala-betacph8175: bras-ithiadiaz-bala-betacph
8176: bhs-24thioph-bala-betadmph8176: bhs-24thioph-bala-betadmph
8177: tolhs-nme35pyr-bala-betafu38177: tolhs-nme35pyr-bala-betafu3
8178: phhs-25methiaz-gly-betahni 30 8179: ibhs-25methiaz-bala-betaphethioa8178: phhs-25methiaz-gly-betahni 30 8179: ibhs-25methiaz-bala-betaphethioa
8180 : tolhs-nme35pyr-bala-betamethioph8180: tolhs-nme35pyr-bala-betamethioph
8181 : tolhs-ithiadiaz-bala-betaphethio8181: tolhs-ithiadiaz-bala-betaphethio
8182 : tolhs-25methiaz-gly-betaipro8182: tolhs-25methiaz-gly-betaipro
8183 : ibhs-24thiaz-gly-betaanaphth 35 8184: bhs-nme35pyr-bala-betabediox8183: ibhs-24thiaz-gly-betaanaphth 35 8184: bhs-nme35pyr-bala-betabediox
8185: 2pmhs-42nmeim-bala-betapym8185: 2 pmhs-42nmeim-bala-betapym
8186: ibhs-25oxaz-gly-betaipro8186: ibhs-25oxaz-gly-betaipro
8187: phhs-24thioph-gly-psdap8187: phhs-24thioph-gly-psdap
8188: bhs-25oxaz-nmgly-betathio38188: bhs-25oxaz-nmgly-betathio3
8189 : bhs-24thioph-bala-betadtrif8189: bras-24thioph-bala-betadtrif
40 8190 : tolhs-ithiadiaz-bala-betamethi40 8190: tolhs-ithiadiaz-bala-betamethi
8191 : tolhs-25methiaz-bala-betabenfu8191: tolhs-25methiaz-bala-betabenfu
8192 : ibhs-24thioph-bala-betadmoph8192: ibhs-24thioph-bala-betadmoph
8193: tolhs-25oxaz-gly-betahb8193: tolhs-25oxaz-gly-betahb
8194: tolhs-me24thiaz-gly-zdap 45 8195: phhs-oxadiaz-gly-betathioph8194: tolhs-me24thiaz-gly-zdap 45 8195: phhs-oxadiaz-gly-betathioph
8196: bhs-25thiaz-gly-betafphe8196: bhs-25thiaz-gly-betafphe
8197: ibhs-24thioph-bala-betaipr 8198: gua-25thioph-gly-betapyr8197: ibhs-24thioph-bala-betaipr 8198: gua-25thioph-gly-betapyr
8199: phhs-nme35pyr-gly-betameph8199: phhs-nme35pyr-gly-betameph
8200: ibhs-25oxaz-gly-zdap8200: ibhs-25oxaz-gly-zdap
8201: ibhs-25methiaz-gly-zdap 5 8202: bhs-24thiaz-ala-betainyl8201: ibhs-25methiaz-gly-zdap 5 8202: bhs-24thiaz-ala-betainyl
8203 : bhs-nme35pyr-bala-betathiome8203: bhs-nme35pyr-bala-betathiome
8204 : bhs-24thiaz-bala-betathiobe8204: bras-24thiaz-bala-betathiobe
8205: tolhs-24thiaz-bala-betapym8205: tolhs-24thiaz-bala-betapym
8206 : tolhs-25methiaz-gly-betathioph8206: tolhs-25methiaz-gly-betathioph
8207 : tolhs-ithiadiaz-bala-betapym8207: tolhs-ithiadiaz-bala-betapym
1010
8208: tolhs-25oxaz-bala-betaimid8208: tolhs-25oxaz-bala-betaimide
8209 : tolhs-ithiadiaz-bala-betaipro8209: tolhs-ithiadiaz-bala-betaipro
8210: bhs-25thiaz-bala-betal3bendi8210: bhs-25thiaz-bala-betal3bendi
8211: 2pmhs-24thioph-gly-betabpy8211: 2 pmhs-24thioph-gly-betabpy
8212 : ibhs-ithiadiaz-bala-betadcph 15 8213: bhs-24thiaz-gly-betabnaphth8212: ibhs-ithiadiaz-bala-betadcph 15 8213: bhs-24thiaz-gly-betabnaphth
8214: bhs-25oxaz-bala-betahmo8214: bras-25oxaz-bala-betahmo
8215: 2py-me24oxaz-leu-betaph8215: 2py-me24oxaz-leu-betaph
8216 : tolhs-25methiaz-gly-betahph8216: tolhs-25methiaz-gly-betahph
8217 : phhs-25oxaz-gly-betapyr 20 8218: bhs-25oxaz-nmgly-betafphe8217: phhs-25oxaz-gly-betapyr 20 8218: bhs-25oxaz-nmgly-betafphe
8219: bim-25thiaz-gly-betameph8219: bim-25thiaz-gly-betameph
8220: bhs-oxadiaz-bala-aspbzla8220: bras-oxadiaz-bala-aspbzla
8221: bim-25oxaz-gly-betahb8221: bim-25oxaz-gly-betahb
8222: phhs-me25thiaz-ala-zdap8222: phhs-me25thiaz-ala-zdap
8223: tolhs-me24oxaz-bala-betapy8223: tolhs-me24oxaz-bala-betapy
25 8224: gua-24thiaz-gly-betahbcph25 8224: gua-24thiaz-gly-betahbcph
8225: bim-24oxaz-ala-betainyl8225: bim-24oxaz-ala-betainyl
8226: 2pmhs-25oxaz-gly-betathio38226: 2 pmhs-25oxaz-gly-betathio3
8227: bhs-25oxaz-bala-betadcphtb8227: bras-25oxaz-bala-betadcphtb
8228 : 2py-me24oxaz-gly-betaph 30 8229: bhs-24thiaz-nmgly-beta34dcph8228: 2py-me24oxaz-gly-betaph 30 8229: bhs-24thiaz-nmgly-beta34dcph
8230 : ibhs-nme35pyr-bala-betal3bendi8230: ibhs-nme35pyr-bala-betal3bendi
8231: bhs-me24thiaz-gly-psdap8231: bhs-me24thiaz-gly-psdap
8232 : ibhs-nme35pyr-bala-betadtrif8232: ibhs-nme35pyr-bala-betadtrif
8233 : tolhs-nme35pyr-bala-betaoxope 35 8234: 2py-25fur-leu-betapy8233: tolhs-nme35pyr-bala-betaoxope 35 8234: 2py-25fur-leu-betapy
8235: tolhs-nme35pyr-bala-betahc8235: tolhs-nme35pyr-bala-betahc
8236: 2py-me24thiaz-ala-psdap8236: 2py-me24thiaz-ala-psdap
8237: bim-me24thiaz-ala-betapy8237: bim-me24thiaz-ala-betapy
8238 : tolhs-25thiaz-gly-betabthioph8238: tolhs-25thiaz-gly-betabthioph
8239: 2py-25thioph-bala-psdap8239: 2py-25thioph-bala-psdap
40 8240 : ibhs-25thiaz-gly-betahdcph40 8240: ibhs-25thiaz-gly-betahdcph
8241 : bim-26py-gly-psdap8241: bim-26py-gly-psdap
8242: 2py-35fur-gly-betapy8242: 2py-35fur-gly-betapy
8243 : phhs-25methiaz-bala-betabph8243: phhs-25methiaz-bala-betabph
8244 : phhs-25thiaz-bala-betahbcph 45 8245: ibhs-24thioph-gly-betadcphtb8244: phhs-25thiaz-bala-betahbcph 45 8245: ibhs-24thioph-gly-betadcphtb
8246: 2py-me25thiaz-leu-betaph8246: 2py-me25thiaz-leu-betaph
8247 : ibhs-25thiaz-gly-betaipr 8248: ibhs-24thioph-gly-betacbph8247: ibhs-25thiaz-gly-betaipr 8248: ibhs-24thioph-gly-betacbph
8249 : ibhs-25methiaz-bala-betaamibe8249: ibhs-25methiaz-bala-betaamibe
8250 : phhs-25methiaz-gly-betapyee8250: phhs-25methiaz-gly-betapyee
8251: bhs-24thioph-bala-betahdbph 5 8252: bhs-24thiaz-gly-aspbzla8251: bhs-24thioph-bala-betahdbph 5 8252: bhs-24thiaz-gly-aspbzla
8253 : phhs-25methiaz-bala-betadcphch8253: phhs-25methiaz-bala-betadcphch
8254 : bhs-nme35pyr-gly-betabph8254: bhs-nme35pyr-gly-betabph
8255: bim-42nmeim-bala-betambiph8255: bim-42nmeim-bala-betambiph
8256: bhs-25thiaz-gly-betaet8256: bhs-25thiaz-gly-betaet
8257 : ibhs-nme35pyr-gly-betaamibe8257: ibhs-nme35pyr-gly-betaamibe
10 8258 : ibhs-oxadiaz-bala-betahmo10 8258: ibhs-oxadiaz-bala-betahmo
8259: tolhs-oxadiaz-bala-asppha8259: tolhs-oxadiaz-bala-asppha
8260: ibhs-nme35pyr-bala-betacph8260: ibhs-nme35pyr-bala-betacph
8261: phhs-ithiadiaz-bala-betabthioph8261: phhs-ithiadiaz-bala-betabthioph
8262: bhs-25thiaz-gly-betafph 15 8263: hyd-25thioph-gly-zdap8262: bhs-25thiaz-gly-betafph 15 8263: hyd-25thioph-gly-zdap
8264: phhs-24thiaz-bala-betahmph8264: phhs-24thiaz-bala-betahmph
8265 : ibhs-nme35pyr-gly-betabnaphth8265: ibhs-nme35pyr-gly-betabnaphth
8266 : tolhs-me25oxaz-bala-betaph8266: tolhs-me25oxaz-bala-betaph
8267 : impy-24thioph-gly-betabediox 20 8268: tolhs-me25oxaz-leu-betadcph8267: impy-24thioph-gly-betabediox 20 8268: tolhs-me25oxaz-leu-betadcph
8269 : tolhs-oxadiaz-gly-betadmoph8269: tolhs-oxadiaz-gly-betadmoph
8270: bhs-26py-gly-betaph8270: bhs-26py-gly-betaph
8271: bhs-24thioph-gly-asppha8271: bhs-24thioph-gly-asppha
8272: bhs-25oxaz-gly-betacph8272: bhs-25oxaz-gly-betacph
8273: bhs-24thiaz-bala-betapbiph8273: bras-24thiaz-bala-betapbiph
25 8274: ibhs-nme35pyr-gly-betaph25 8274: ibhs-nme35pyr-gly-betaph
8275: phhs-25thiaz-bala-beta3quin8275: phhs-25thiaz-bala-beta3quin
8276: dhim-42pym-gly-betameph8276: dhim-42pym-gly-betameph
8277 : 2py-25methiaz-bala-beta34dcph8277: 2py-25methiaz-bala-beta34dcph
8278: tolhs-25methiaz-gly-betaphethioa 30 8279: bhs-24thioph-bala-betathio38278: tolhs-25methiaz-gly-betaphethioa 30 8279: bhs-24thioph-bala-betathio3
8280: bim-24thioph-bala-betampy8280: bim-24thioph-bala-betampy
8281: phhs-24thiaz-gly-betabph8281: phhs-24thiaz-gly-betabph
8282: bim-24thiaz-bala-betaimid8282: bim-24thiaz-bala-betaimide
8283 : tolhs-me25thiaz-bala-betaph 35 8284: phhs-24thioph-gly-zdapee8283: tolhs-me25thiaz-bala-betaph 35 8284: phhs-24thioph-gly-zdapee
8285: phhs-24thioph-bala-betadcph8285: phhs-24thioph-bala-betadcph
8286: tolhs-ithiadiaz-gly-betampy8286: tolhs-ithiadiaz-gly-betampy
8287 : bhs-25methiaz-gly-csdap8287: bhs-25methiaz-gly-csdap
8288: bhs-42nmeim-ala-psdap8288: bhs-42nmeim-ala-psdap
8289: phhs-oxadiaz-gly-betabmph8289: phhs-oxadiaz-gly-betabmph
40 8290: tolhs-oxadiaz-gly-betaheph40 8290: tolhs-oxadiaz-gly-betaheph
8291: bhs-oxadiaz-ala-betapy8291: bras-oxadiaz-ala-betapy
8292: ibhs-oxadiaz-bala-betahni8292: ibhs-oxadiaz-bala-betahni
8293 : ibhs-24thioph-bala-betaph8293: ibhs-24thioph-bala-betaph
8294 : phhs-25oxaz-bala-psdap 45 8295: tolhs-me25thioph-leu-betadcph8294: phhs-25oxaz-bala-psdap 45 8295: tolhs-me25thioph-leu-betadcph
8296: phhs-25thiaz-bala-betahni8296: phhs-25thiaz-bala-betahni
8297 : phhs-nme35pyr-bala-beta34meoph 8298 : phhs-nme35pyr-bala-betafphe8297: phhs-nme35pyr-bala-beta34meoph 8298: phhs-nme35pyr-bala-betafphe
8299: 2py-25thiaz-bala-betaoxope8299: 2py-25thiaz-bala-betaoxope
8300: tolhs-ithiadiaz-bala-psdapee8300: tolhs-ithiadiaz-bala-psdapee
8301 : tolhs-25methiaz-gly-betapbiph 5 8302: ibhs-ithiadiaz-bala-betabmph8301: tolhs-25methiaz-gly-betapbiph 5 8302: ibhs-ithiadiaz-bala-betabmph
8303: bim-24thiaz-gly-aspbzla8303: bim-24thiaz-gly-aspbzla
8304 : phhs-oxadiaz-bala-betabthioph8304: phhs-oxadiaz-bala-betabthioph
8305: bhs-25fur-leu-psdap8305: bras-25fur-leu-psdap
8306: bhs-nme35pyr-gly-betadcphch8306: bhs-nme35pyr-gly-betadcphch
8307: 2py-oxadiaz-leu-zdap8307: 2py-oxadiaz-leu-zdap
1010
8308: tolhs-24thioph-bala-betadmph8308: tolhs-24thioph-bala-betadmph
8309: 2pmhs-25methiaz-phe-zdap8309: 2 pmhs-25methiaz-phe-zdap
8310 : phhs-25methiaz-bala-betapyee8310: phhs-25methiaz-bala-betapyee
8311: bhs-25methiaz-ala-betameph8311: bhs-25methiaz-ala-betameph
8312: phhs-me24oxaz-leu-psdap 15 8313: 2pmhs-42nmeim-bala-betampy8312: phhs-me24oxaz-leu-psdap 15 8313: 2 pmhs-42nmeim-bala-betampy
8314: bhs-ithiadiaz-gly-betaoxaz8314: bhs-ithiadiaz-gly-betaoxaz
8315: tolhs-me25thiaz-leu-betadcph8315: tolhs-me25thiaz-leu-betadcph
8316 : tolhs-24thioph-bala-betahmofu8316: tolhs-24thioph-bala-betahmofu
8317: bim-24thiaz-gly-betapbiph 20 8318: tolhs-me24thiaz-ala-beta34meoph8317: bim-24thiaz-gly-betapbiph 20 8318: tolhs-me24thiaz-ala-beta34meoph
8319: bhs-24thioph-nmgly-betafphe8319: bhs-24thioph-nmgly-betafphe
8320: ibhs-24thioph-bala-aspaba8320: ibhs-24thioph-bala-aspaba
8321: bhs-ithiadiaz-nmgly-betadmph8321: bhs-ithiadiaz-nmgly-betadmph
8322: tolhs-25thiaz-gly-betaimid8322: tolhs-25thiaz-gly-betaimide
8323 : bhs-24thiaz-ala-beta34meoph8323: bhs-24thiaz-ala-beta34meoph
25 8324: tolhs-25thiaz-bala-betafu325 8324: tolhs-25thiaz-bala-betafu3
8325: phhs-25methiaz-gly-betapy8325: phhs-25methiaz-gly-betapy
8326: tolhs-25methiaz-gly-betadcphee8326: tolhs-25methiaz-gly-betadcphee
8327 : tolhs-25methiaz-gly-betafu28327: tolhs-25methiaz-gly-betafu2
8328: phhs-24thiaz-bala-betahni 30 8329: bhs-25oxaz-gly-beta34dcph8328: phhs-24thiaz-bala-betahni 30 8329: bhs-25oxaz-gly-beta34dcph
8330: ibhs-25methiaz-bala-betacph8330: ibhs-25methiaz-bala-betacph
8331: phhs-24thioph-gly-aspaba8331: phhs-24thioph-gly-aspaba
8332: bhs-53pyrazo-ala-zdap8332: bhs-53pyrazo-ala-zdap
8333: bhs-ithiadiaz-bala-psdaptb 35 8334: ibhs-oxadiaz-bala-psdapee8333: bhs-ithiadiaz-bala-psdaptb 35 8334: ibhs-oxadiaz-bala-psdapee
8335: bhs-nme35pyr-gly-ibsdap8335: bhs-nme35pyr-gly-ibsdap
8336: bhs-52thiaz-ala-betameph8336: bhs-52thiaz-ala-betameph
8337: bhs-nme35pyr-nmgly-betadito8337: bhs-nme35pyr-nmgly-betadito
8338: phhs-24thioph-bala-betadhbfu8338: phhs-24thioph-bala-betadhbfu
8339: phhs-25oxaz-bala-betaanaphth8339: phhs-25oxaz-bala-betaanaphth
40 8340 : bhs-nme35pyr-gly-betacthioph40 8340: bhs-nme35pyr-gly-betacthioph
8341: bhs-25methiaz-gly-betadmoph8341: bhs-25methiaz-gly-betadmoph
8342: tolhs-24thioph-gly-betabph8342: tolhs-24thioph-gly-betabph
8343: phhs-24thiaz-gly-zdap8343: phhs-24thiaz-gly-zdap
8344: bhs-25oxaz-gly-betadbph 45 8345: tolhs-ithiadiaz-bala-betameph8344: bhs-25oxaz-gly-betadbph 45 8345: tolhs-ithiadiaz-bala-betameph
8346: phhs-25oxaz-gly-betapy8346: phhs-25oxaz-gly-betapy
8347: bhs-25methiaz-bala-betadhbfu 8348: bim-25oxaz-leu-zdap8347: bhs-25methiaz-bala-betadhbfu 8348: bim-25oxaz-leu-zdap
8349: bhs-ithiadiaz-gly-csdap8349: bhs-ithiadiaz-gly-csdap
8350: tolhs-24thiaz-gly-zdaptb8350: tolhs-24thiaz-gly-zdaptb
8351 : ibhs-nme35pyr-bala-betaph 5 8352: ibhs-25thiaz-bala-betapyr8351: ibhs-nme35pyr-bala-betaph 5 8352: ibhs-25thiaz-bala-betapyr
8353: ibhs-24thiaz-gly-betahmo8353: ibhs-24thiaz-gly-betahmo
8354 : ur-25thiaz-gly-betadcph8354: ur-25thiaz-gly-betadcph
8355 : ibhs-25methiaz-bala-betabnaphth8355: ibhs-25methiaz-bala-betabnaphth
8356: tolhs-24thiaz-gly-asppha8356: tolhs-24thiaz-gly-asppha
8357: bhs-24thiaz-nmgly-betaoxaz8357: bhs-24thiaz-nmgly-betaoxaz
10 8358: ibhs-25methiaz-gly-betacph10 8358: ibhs-25methiaz-gly-betacph
8359 : bhs-25oxaz-ala-psdap8359: bhs-25oxaz-ala-psdap
8360: bim-ithiadiaz-bala-asppha8360: bim-ithiadiaz-bala-asppha
8361 : dhim-26py-gly-betambiph8361: dhim-26py-gly-betambiph
8362 : phhs-25oxaz-gly-beta34meoph 15 8363: 2py-ithiadiaz-ala-zdap8362: phhs-25oxaz-gly-beta34meoph 15 8363: 2py-ithiadiaz-ala-zdap
8364: 2pmhs-42nmeim-bala-betadhbfu8364: 2 pmhs-42nmeim-bala-betadhbfu
8365 : phhs-nme35pyr-gly-betabpy8365: phhs-nme35pyr-gly-betabpy
8366 : ibhs-ithiadiaz-gly-betadhbfu8366: ibhs-ithiadiaz-gly-betadhbfu
8367 : bhs-25methiaz-bala-betamethi 20 8368: tolhs-oxadiaz-bala-betafluo8367: bhs-25methiaz-bala-betamethi 20 8368: tolhs-oxadiaz-bala-betafluo
8369 : phhs-25oxaz-gly-betapyee8369: phhs-25oxaz-gly-betapyee
8370: phhs-25thiaz-bala-betapyee8370: phhs-25thiaz-bala-betapyee
8371: ibhs-oxadiaz-gly-betacph8371: ibhs-oxadiaz-gly-betacph
8372: bim-53pyrazo-bala-betapy8372: bim-53pyrazo-bala-betapy
8373 : phhs-25oxaz-bala-betabph8373: phhs-25oxaz-bala-betabph
25 8374 : bhs-24thioph-bala-betaphethio25 8374: bhs-24thioph-bala-betaphethio
8375: 2py-me25oxaz-ala-betaph8375: 2py-me25oxaz-ala-betaph
8376: tolhs-nme35pyr-gly-betatos8376: tolhs-nme35pyr-gly-betatos
8377: ibhs-nme35pyr-bala-betaoxope8377: ibhs-nme35pyr-bala-betaoxope
8378: tolhs-25thiaz-bala-betabpy 30 8379: gua-25thiaz-gly-betabnaphth8378: tolhs-25thiaz-bala-betabpy 30 8379: gua-25thiaz-gly-betabnaphth
8380 : bhs-24thioph-nmgly-beta34meoph8380: bhs-24thioph-nmgly-beta34meoph
8381 : impy-42nmeim-bala-betaph8381: impy-42nmeim-bala-betaph
8382 : ibhs-24thioph-gly-betapy8382: ibhs-24thioph-gly-betapy
8383 : tolhs-25thiaz-gly-betacthioph 35 8384: tolhs-25thiaz-gly-betabnaphth8383: tolhs-25thiaz-gly-betacthioph 35 8384: tolhs-25thiaz-gly-betabnaphth
8385: bhs-24thioph-gly-betafphe8385: bhs-24thioph-gly-betafphe
8386 : tolhs-oxadiaz-bala-betadcph8386: tolhs-oxadiaz-bala-betadcph
8387 : bim-25thiaz-gly-betaanaphth8387: bim-25thiaz-gly-beta-anaphth
8388 : 2py-ithiadiaz-bala-betadcph8388: 2py-ithiadiaz-bala-betadcph
8389: dhim-53pyrazo-gly-betameph8389: dhim-53pyrazo-gly-betameph
40 8390: ibhs-25thiaz-gly-beta34dcph40 8390: ibhs-25thiaz-gly-beta34dcph
8391: tolhs-25thiaz-bala-beta3quin8391: tolhs-25thiaz-bala-beta3quin
8392: bhs-24thioph-bala-betadito8392: bhs-24thioph-bala-betadito
8393: gua-24oxaz-gly-betabph8393: gua-24oxaz-gly-betabph
8394 : 2py-triaz-ala-betadcph 45 8395: bhs-25oxaz-bala-psdapch8394: 2py-triaz-ala-betadcph 45 8395: bhs-25oxaz-bala-psdapch
8396 : bhs-nme35pyr-nmgly-betameph8396: bhs-nme35pyr-nmgly-betameph
8397: phhs-25oxaz-bala-betah35dc 8398: impy-24thiaz-bala-betamesu8397: phhs-25oxaz-bala-betah35dc 8398: impy-24thiaz-bala-betamesu
8399: 2pmhs-25oxaz-bala-betaheph8399: 2 pmhs-25oxaz-bala-betaheph
8400 : bhs-25oxaz-bala-beta23meoph8400: bhs-25oxaz-bala-beta23meoph
8401: impy-25oxaz-bala-betahdcph 5 8402: 2py-me25oxaz-gly-zdap8401: impy-25oxaz-bala-betahdcph 5 8402: 2py-me25oxaz-gly-zdap
8403: phhs-24thiaz-bala-betacph8403: phhs-24thiaz-bala-betacph
8404: phhs-oxadiaz-bala-betacph8404: phhs-oxadiaz-bala-betacph
8405 : tolhs-nme35pyr-bala-betapych8405: tolhs-nme35pyr-bala-betapych
8406: tolhs-25oxaz-bala-betamethioph8406: tolhs-25oxaz-bala-betamethioph
8407 : bhs-ithiadiaz-gly-beta34dcph8407: bhs-ithiadiaz-gly-beta34dcph
10 8408: tolhs-me25thioph-leu-zdap10 8408: tolhs-me25thioph-leu-zdap
8409: ibhs-25thiaz-bala-betadmoph8409: ibhs-25thiaz-bala-betadmoph
8410: phhs-25thiaz-bala-zdapee8410: phhs-25thiaz-bala-zdapee
8411: bhs-oxadiaz-gly-betatbuph8411: bhs-oxadiaz-gly-betatbuph
8412 : bhs-42nmeim-bala-betatbuph 15 8413: 2py-42nmeim-bala-betadmph8412: bhs-42nmeim-bala-betatbuph 15 8413: 2py-42nmeim-bala-betadmph
8414: phhs-25oxaz-bala-betaoxaz8414: phhs-25oxaz-bala-betaoxaz
8415: 2py-24oxaz-gly-betameph8415: 2py-24oxaz-gly-betameph
8416 : tolhs-ithiadiaz-bala-betabenfu8416: tolhs-ithiadiaz-bala-betabenfu
8417: 2py-42nmeim-phg-betadcph 20 8418: ibhs-24thiaz-gly-betahc8417: 2py-42nmeim-phg-betadcph 20 8418: ibhs-24thiaz-gly-betahc
8419: phhs-25thiaz-gly-betabediox8419: phhs-25thiaz-gly-betabediox
8420 : tolhs-24thioph-bala-betatrif8420: tolhs-24thioph-bala-betatrif
8421 : bhs-25f r-bala-psdap8421: bhs-25f r-bala-psdap
8422: ibhs-25thiaz-bala-betaibph8422: ibhs-25thiaz-bala-betaibph
8423: tolhs-nme35pyr-bala-psdapch8423: tolhs-nme35pyr-bala-psdapch
25 8424: tolhs-24thioph-gly-betaph25 8424: tolhs-24thioph-gly-betaph
8425 : bhs-ithiadiaz-gly-betabnaphth8425: bhs-ithiadiaz-gly-betabnaphth
8426: bim-25methiaz-ala-zdap8426: bim-25methiaz-ala-zdap
8427 : ibhs-ithiadiaz-gly-betafluo8427: ibhs-ithiadiaz-gly-betafluo
8428: bhs-25thiaz-bala-betaf 2 30 8429: phhs-nme35pyr-gly-csdap8428: bhs-25thiaz-bala-betaf 2 30 8429: phhs-nme35pyr-gly-csdap
8430: thpym-24oxaz-gly-betahdcph8430: thpym-24oxaz-gly-betahdcph
8431: bim-25thioph-gly-betadcph8431: bim-25thioph-gly-betadcph
8432: bhs-25oxaz-bala-betadmoph8432: bras-25oxaz-bala-betadmoph
8433 : bhs-24thioph-gly-psdaptb 35 8434: bim-me24oxaz-ala-psdap8433: bhs-24thioph-gly-psdaptb 35 8434: bim-me24oxaz-ala-psdap
8435 : gua-26py-gly-betadcph8435: gua-26py-gly-betadcph
8436 : bhs-ithiadiaz-bala-betapytb8436: bhs-ithiadiaz-bala-betapytb
8437 : phhs-25methiaz-gly-betadito8437: phhs-25methiaz-gly-betadito
8438: impy-24thiaz-bala-betah35dc8438: impy-24thiaz-bala-betah35dc
8439: ibhs-24thiaz-bala-betapyr8439: ibhs-24thiaz-bala-betapyr
40 8440: bhs-25thiaz-gly-betameph40 8440: bhs-25thiaz-gly-betameph
8441: tolhs-25oxaz-gly-betabenfu8441: tolhs-25oxaz-gly-betabenfu
8442: 2py-25thiaz-leu-betadcph8442: 2py-25thiaz-leu-betadcph
8443 : bhs-24thiaz-gly-betacbph8443: bhs-24thiaz-gly-betacbph
8444: bhs-25 hiaz-bala-busu2be 45 8445: bhs-oxadiaz-gly-betaimid8444: bhs-25 hiaz-bala-busu2be 45 8445: bhs-oxadiaz-gly-betaimid
8446: ibhs-oxadiaz-gly-betaftrif8446: ibhs-oxadiaz-gly-betaftrif
8447 : bhs-ithiadiaz-bala-betah35dc 8448: bhs-25methiaz-bala-betaftrif8447: bhs-ithiadiaz-bala-betah35dc 8448: bras-25methiaz-bala-betaftrif
8449: phhs-24thiaz-gly-betahmph8449: phhs-24thiaz-gly-betahmph
8450 : tolhs-me25thiaz-gly-betadcph8450: tolhs-me25thiaz-gly-betadcph
8451: phhs-me24thiaz-bala-psdap 5 8452: 2py-me24thioph-ala-betadcph8451: phhs-me24thiaz-bala-psdap 5 8452: 2py-me24thioph-ala-betadcph
8453: bhs-24thioph-bala-betadmoph8453: bras-24thioph-bala-betadmoph
8454: ibhs-25thiaz-gly-betapym8454: ibhs-25thiaz-gly-betapym
8455: phhs-24thiaz-gly-betaoxaz8455: phhs-24thiaz-gly-betaoxaz
8456: 2py-25thiaz-bala-asppha8456: 2py-25thiaz-bala-asppha
8457 : bhs-me25thioph-leu-betadcph8457: bhs-me25thioph-leu-betadcph
1010
8458: phhs-24thiaz-gly-betabpy8458: phhs-24thiaz-gly-betabpy
8459: bim-25oxaz-gly-betapy8459: bim-25oxaz-gly-betapy
8460: phhs-24thioph-gly-betapytb8460: phhs-24thioph-gly-betapytb
8461 : ibhs-ithiadiaz-gly-betatrif8461: ibhs-ithiadiaz-gly-betatrif
8462: bhs-24thiaz-bala-csdap 15 8463: phhs-ithiadiaz-bala-zdapee8462: bhs-24thiaz-bala-csdap 15 8463: phhs-ithiadiaz-bala-zdapee
8464: 2py-25fur-ala-psdap8464: 2py-25fur-ala-psdap
8465: tolhs-me25oxaz-bala-betapy8465: tolhs-me25oxaz-bala-betapy
8466: ibhs-nme35pyr-bala-betadito8466: ibhs-nme35pyr-bala-betadito
8467: 2pmhs-24thioph-gly-betahb 20 8468: thpym-24thiaz-gly-betahcbph8467: 2 pmhs-24thioph-gly-betahb 20 8468: thpym-24thiaz-gly-betahcbph
8469 : ibhs-ithiadiaz-gly-betahcbph8469: ibhs-ithiadiaz-gly-betahcbph
8470: ibhs-oxadiaz-gly-betapyr8470: ibhs-oxadiaz-gly-betapyr
8471: ibhs-25oxaz-gly-betafph8471: ibhs-25oxaz-gly-betafph
8472: phhs-24thioph-gly-psdaptb8472: phhs-24thioph-gly-psdaptb
8473: bhs-25oxaz-gly-betafu28473: bhs-25oxaz-gly-betafu2
2525
8474 : ibhs-25methiaz-gly-betadcphtb8474: ibhs-25methiaz-gly-betadcphtb
8475: dhim-24thiaz-gly-psdap8475: dhim-24thiaz-gly-psdap
8476: bhs-ithiadiaz-bala-betafu28476: bhs-ithiadiaz-bala-betafu2
8477 : tolhs-25methiaz-bala-betameph8477: tolhs-25methiaz-bala-betameph
8478: phhs-25thiaz-bala-betafu2 30 8479: gua-24oxaz-gly-busu2be8478: phhs-25thiaz-bala-betafu2 30 8479: gua-24oxaz-gly-busu2be
8480: phhs-nme35pyr-bala-betahc8480: phhs-nme35pyr-bala-betahc
8481: phhs-24thiaz-gly-betahc8481: phhs-24thiaz-gly-betahc
8482: phhs-25oxaz-gly-asppha8482: phhs-25oxaz-gly-asppha
8483: phhs-nme35pyr-gly-betafu2 35 8484: ibhs-24thioph-bala-betabmph8483: phhs-nme35pyr-gly-betafu2 35 8484: ibhs-24thioph-bala-betabmph
8485: phhs-ithiadiaz-gly-betaol8485: phhs-ithiadiaz-gly-betaol
8486: bhs-25methiaz-nmgly-betadhbf8486: bhs-25methiaz-nmgly-betadhbf
8487 : tolhs-24thioph-gly-betaanaphth8487: tolhs-24thioph-gly-betaanaphth
8488: tolhs-24thiaz-bala-betameph8488: tolhs-24thiaz-bala-betameph
8489: phhs-25thiaz-bala-betamesu8489: phhs-25thiaz-bala-betamesu
40 8490: tolhs-25methiaz-gly-asppha40 8490: tolhs-25methiaz-gly-asppha
8491: ibhs-ithiadiaz-bala-betabpy8491: ibhs-ithiadiaz-bala-betabpy
8492: bhs-25thiaz-gly-betahb8492: bhs-25thiaz-gly-betahb
8493: phhs-25oxaz-bala-betambiph8493: phhs-25oxaz-bala-betambiph
8494 : bim-35fur-ala-betadcph 45 8495: bhs-oxadiaz-bala-betacbph8494: bim-35fur-ala-betadcph 45 8495: bhs-oxadiaz-bala-betacbph
8496: bhs-nme35pyr-bala-betadcphtb8496: bhs-nme35pyr-bala-betadcphtb
8497: bhs-26py-gly-betadcph 8498: ibhs-25thiaz-bala-betafu3 8499: phhs-24thiaz-gly-suabu 8500: bim-24oxaz-ala-betadcph 8501: bhs-oxadiaz-nmgly-betafphe 8502: bhs-24thioph-bala-betampy 8503: bim-25methiaz-bala-zdap 8504: tolhs-oxadiaz-gly-betaibph 8505: 2py-me24thiaz-gly-psdap 8506: thpym-42nmeim-bala-betapy 8507: bhs-25oxaz-bala-betahni8497: bhs-26py-gly-betadcph 8498: ibhs-25thiaz-bala-betafu3 8499: phhs-24thiaz-gly-suabu 8500: bim-24oxaz-ala-betadcph 8501: bhs-oxadiaz-nmgly-betafphe 8502: bhs-24thioph-bala-betampy 8503: bim-25methiaz -bala-zdap 8504: tolhs-oxadiaz-gly-betaibph 8505: 2py-me24thiaz-gly-psdap 8506: thpym-42nmeim-bala-betapy 8507: bhs-25oxaz-bala-betahni
10 8508: 2py-oxadiaz-leu-betadcph 8509: ibhs-oxadiaz-bala-zdapee 8510: gua-42nmeim-bala-psdap 8511: gua-25thioph-gly-beta35dbph 8512: bhs-25oxaz-gly-betafph10 8508: 2py-oxadiaz-leu-betadcph 8509: ibhs-oxadiaz-bala-zdapee 8510: gua-42nmeim-bala-psdap 8511: gua-25thioph-gly-beta35dbph 8512: bhs-25oxaz-gly-betafph
15 8513: ibhs-nme35pyr-gly-betahni 8514 : ibhs-ithiadiaz-bala-betafu2 8515: phhs-25oxaz-bala-betadmoph 8516: bim-triaz-leu-betapy 8517: 2py-24oxaz-gly-betadcph15 8513: ibhs-nme35pyr-gly-betahni 8514: ibhs-ithiadiaz-bala-betafu2 8515: phhs-25oxaz-bala-betadmoph 8516: bim-triaz-leu-betapy 8517: 2py-24oxaz-gly-betadcph
20 8518: tolhs-25thiaz-gly-betapy 8519: tolhs-ithiadiaz-gly-csdap 8520 : tolhs-25thiaz-bala-betathio3 8521: 2py-25oxaz-gly-betabediox 8522 : ibhs-ithiadiaz-bala-betathio3 8523 : tolhs-ithiadiaz-bala-beta3quin20 8518: tolhs-25thiaz-gly-betapy 8519: tolhs-ithiadiaz-gly-csdap 8520: tolhs-25thiaz-bala-betathio3 8521: 2py-25oxaz-gly-betabediox 8522: ibhs-ithiadiaz-bala-betathios- 8523: tolh ithiadiaz-bala-beta3quin
25 8524: agua-25thiaz-gly-psdap 8525: ibhs-ithiadiaz-gly-betameph 8526: phhs-me25oxaz-ala-zdap 8527: 2pmhs-24thiaz-bala-zdap 8528: bim-oxadiaz-bala-aspbzla25 8524: agua-25thiaz-gly-psdap 8525: ibhs-ithiadiaz-gly-betameph 8526: phhs-me25oxaz-ala-zdap 8527: 2 pmhs-24thiaz-bala-zdap 8528: bim-oxadiaz-bala-aspbzla
30 8529: bhs-25thiaz-ala-betathioph 8530: bhs-nme35pyr-bala-beta4bph 8531 : phhs-me25thiaz-bala-beta34meoph 8532: bhs-24thioph-gly-betapych 8533: gua-24oxaz-gly-betadito30 8529: bhs-25thiaz-ala-betathioph 8530: bhs-nme35pyr-bala-beta4bph 8531: phhs-me25thiaz-bala-beta34meoph 8532: bhs-24thioph-gly-betapych 8533: gua-24oxaz-gly-betadito
35 8534: tolhs-me25thioph-gly-betaph 8535 : impy-25methiaz-gly-beta34meoph 8536 : phhs-ithiadiaz-gly-betacbph 8537 : ibhs-nme35pyr-bala-betaftrif 8538: 2py-25thioph-leu-psdap 8539: phhs-25oxaz-bala-betatos35 8534: tolhs-me25thioph-gly-betaph 8535: impy-25methiaz-gly-beta34meoph 8536: phhs-ithiadiaz-gly-betacbph 8537: ibhs-nme35pyr-bala-betaftrif 8538: 2py-25thioph-leu-psdap 8539: phhs- 25oxaz-bala-betatos
40 8540: dhim-24thioph-gly-betapy 8541 : tolhs-24thioph-bala-betabdimo 8542 : bhs-42nmeim-bala-betathio3 8543 : bhs-42nmeim-ala-zdap 8544: phhs-nme35pyr-bala-betabpy40 8540: dhim-24thioph-gly-betapy 8541: tolhs-24thioph-bala-betabdimo 8542: bhs-42nmeim-bala-betathio3 8543: bhs-42nmeim-ala-zdap 8544: phhs-nme35pyr-bala-betabpy
45 8545: ibhs-nme35pyr-gly-betacbph 8546 : bhs-25methiaz-bala-betadcphtb 8547 : tolhs-me24oxaz-gly-beta34meoph 8548 : tolhs-25oxaz-bala-betaftrif 8549: 3pmhs-24thiaz-gly-betapy 8550: bhs-24thioph-bala-betaamibe 8551: bim-24thioph-bala-zdap 8552: ibhs-24thiaz-gly-beta3quin 8553: tolhs-nme35pyr-gly-betafluo 8554: gua-26py-gly-betatrif 8555: phhs-me24thiaz-leu-betadcph 8556: 2pmhs-42nmeim-gly-betabdimo 8557: bim-52thiaz-gly-betapy45 8545: ibhs-nme35pyr-gly-betacbph 8546: bhs-25methiaz-bala-betadcphtb 8547: tolhs-me24oxaz-gly-beta34meoph 8548: tolhs-25oxaz-bala-betaftrif 8549: 3 pmhs-24thiaz-gly-betapy 8550: bhs-24thioph-bala-betaamibe 8551: bim-24thioph-bala-zdap 8552: ibhs-24thiaz-gly-beta3quin 8553: tolhs-nme35p -gly-betafluo 8554: gua-26py-gly-betatrif 8555: phhs-me24thiaz-leu-betadcph 8556: 2 pmhs-42nmeim-gly-betabdimo 8557: bim-52thiaz-gly-betapy
10 8558: phhs-25thiaz-gly-csdap 8559: phhs-25oxaz-gly-betahcbph 8560: phhs-oxadiaz-bala-betambiph 8561: ibhs-25oxaz-bala-ibsdap 8562 : tolhs-24thioph-gly-betaipro10 8558: phhs-25thiaz-gly-csdap 8559: phhs-25oxaz-gly-betahcbph 8560: phhs-oxadiaz-bala-betambiph 8561: ibhs-25oxaz-bala-ibsdap 8562: tolhs-24thioph-gly-betaipro
15 8563: bhs-24thiaz-bala-betaanaphth 8564 : tolhs-25methiaz-gly-betatos 8565 : tolhs-ithiadiaz-bala-betatbuph 8566: bhs-oxadiaz-gly-suabu 8567: 2pmhs-42nmeim-gly-betafbph15 8563: bhs-24thiaz-bala-betaanaphth 8564: tolhs-25methiaz-gly-betatos 8565: tolhs-ithiadiaz-bala-betatbuph 8566: bhs-oxadiaz-gly-suabu 8567: 2 pmhs-42nmeim-gly-betafbph
20 8568: 2py-me24thioph-bala-zdap 8569: phhs-nme35pyr-bala-suabu 8570 : phhs-24thiaz-bala-betahcbph 8571: phhs-25thiaz-bala-betapych 8572: ibhs-24thioph-gly-psdapch 8573 : ibhs-24thiaz-gly-betaphethioa20 8568: 2py-me24thioph-bala-zdap 8569: phhs-nme35pyr-bala-suabu 8570: phhs-24thiaz-bala-betahcbph 8571: phhs-25thiaz-bala-betapych 8572: ibhs-24thioph-gly-psdapch 8573: ibhs 24thiaz-gly-betaphethioa
25 8574 : tolhs-25methiaz-bala-betadtrif 8575: ibhs-ithiadiaz-bala-zdap 8576: bhs-24thioph-bala-betacph 8577: bhs-nme35pyr-gly-betathioph 8578: nmhs-25thioph-gly-betameph25 8574: tolhs-25methiaz-bala-betadtrif 8575: ibhs-ithiadiaz-bala-zdap 8576: bhs-24thioph-bala-betacph 8577: bhs-nme35pyr-gly-betathioph 8578: nmhs-25thioph-gly-betameph
30 8579: bhs-ithiadiaz-bala-betaheph 8580 : ibhs-oxadiaz-gly-betamethioph 8581 : phhs-24thioph-gly-betathiobe 8582: bhs-oxadiaz-gly-psdapch 8583: bim-26py-ala-betameph30 8579: bhs-ithiadiaz-bala-betaheph 8580: ibhs-oxadiaz-gly-betamethioph 8581: phhs-24thioph-gly-betathiobe 8582: bhs-oxadiaz-gly-psdapch 8583: bim-26py-ala-betameph
35 8584: tolhs-25oxaz-gly-betaamibe 8585 : phhs-24thioph-bala-betal3bendi 8586: phhs-25methiaz-bala-betadbph 8587: 2pmhs-25oxaz-bala-betahni 8588: ibhs-24thioph-gly-aspibua 8589: dhim-25thioph-gly-psdap35 8584: tolhs-25oxaz-gly-betaamibe 8585: phhs-24thioph-bala-betal3bendi 8586: phhs-25methiaz-bala-betadbph 8587: 2 pmhs-25oxaz-bala-betahni 8588: ibhs-24thioph-gly-aspibua 8589: dhim- 25thioph-gly-psdap
40 8590: phhs-25oxaz-gly-betaipro 8591 : bhs-25methiaz-gly-beta34meoph 8592: bhs-me25thioph-leu-betaph 8593: 2py-25oxaz-bala-betah35dc 8594 : 2pmhs-24thioph-gly-betadtrif40 8590: phhs-25oxaz-gly-betaipro 8591: bhs-25methiaz-gly-beta34meoph 8592: bhs-me25thioph-leu-betaph 8593: 2py-25oxaz-bala-betah35dc 8594: 2 pmhs-24thioph-gly-betadtrif
45 8595: phhs-nme35pyr-bala-psdapch 8596 : tolhs-25methiaz-gly-betadito 8597 : ibhs-25oxaz-gly-beta34meoph 8598: bhs-25oxaz-bala-betaoxope45 8595: phhs-nme35pyr-bala-psdapch 8596: tolhs-25methiaz-gly-betadito 8597: ibhs-25oxaz-gly-beta34meoph 8598: bhs-25oxaz-bala-betaoxope
8599: phhs-nme35pyr-gly-betadcphch8599: phhs-nme35pyr-gly-betadcphch
8600 : bhs-24thioph-gly-betathioph8600: bhs-24thioph-gly-betathioph
8601 : phhs-25thiaz-gly-betaphethioa 5 8602: phhs-25thiaz-gly-betambiph8601: phhs-25thiaz-gly-betaphethioa 5 8602: phhs-25thiaz-gly-betambiph
8603 : tolhs-ithiadiaz-gly-betafph8603: tolhs-ithiadiaz-gly-betafph
8604 : bhs-nme35pyr-bala-betaph8604: bhs-nme35pyr-bala-betaph
8605: ibhs-25oxaz-gly-betapytb8605: ibhs-25oxaz-gly-betapytb
8606: bim-24thiaz-gly-aspaba8606: bim-24thiaz-gly-aspaba
8607: gua-26py-gly-busu2be8607: gua-26py-gly-busu2be
8608: bhs-25oxaz-ala-beta34meoph8608: bhs-25oxaz-ala-beta34meoph
8609: phhs-nme35pyr-bala-betapyr8609: phhs-nme35pyr-bala-betapyr
8610: phhs-ithiadiaz-gly-beta35dbph8610: phhs-ithiadiaz-gly-beta35dbph
8611 : tolhs-me24oxaz-leu-betadcph8611: tolhs-me24oxaz-leu-betadcph
8612 : bhs-24thiaz-gly-betahph 15 8613: phhs-25oxaz-gly-csdap8612: bhs-24thiaz-gly-betahph 15 8613: phhs-25oxaz-gly-csdap
8614: tolhs-25thiaz-gly-betatos8614: tolhs-25thiaz-gly-betatos
8615 : tolhs-25methiaz-gly-beta23meoph8615: tolhs-25methiaz-gly-beta23meoph
8616: tolhs-24thiaz-bala-asppha8616: tolhs-24thiaz-bala-asppha
8617: ibhs-ithiadiaz-gly-psdaptb 20 8618: bhs-me24thiaz-bala-betapy8617: ibhs-ithiadiaz-gly-psdaptb 20 8618: bhs-me24thiaz-bala-betapy
8619: phhs-25methiaz-bala-betahc8619: phhs-25methiaz-bala-betahc
8620: ibhs-24thioph-bala-betamesu8620: ibhs-24thioph-bala-betamesu
8621: bhs-25oxaz-gly-csdap8621: bhs-25oxaz-gly-csdap
8622: ibhs-nme35pyr-gly-psdapee8622: ibhs-nme35pyr-gly-psdapee
8623: ibhs-25methiaz-gly-betafu3 25 8624: 2py-me24thi.az-ala-betadcph8623: ibhs-25methiaz-gly-betafu3 25 8624: 2py-me24thi.az-ala-betadcph
8625: bhs-25thiaz-bala-betabdimo8625: bras-25thiaz-bala-betabdimo
8626: phhs-nme35pyr-bala-betapych8626: phhs-nme35pyr-bala-betapych
8627: phhs-me24thiaz-ala-betapy8627: phhs-me24thiaz-ala-betapy
8628: bhs-25thiaz-gly-betaanaphth 30 8629: phhs-ithiadiaz-gly-betadcph8628: bhs-25thiaz-gly-betaanaphth 30 8629: phhs-ithiadiaz-gly-betadcph
8630: bhs-25oxaz-gly-betapyr8630: bhs-25oxaz-gly-betapyr
8631 : phhs-nme35pyr-gly-betaphethio8631: phhs-nme35pyr-gly-betaphethio
8632: phhs-25oxaz-gly-betameph8632: phhs-25oxaz-gly-betameph
8633: ibhs-25oxaz-gly-betabenfu 35 8634: phhs-24thiaz-bala-betapyr8633: ibhs-25oxaz-gly-betabenfu 35 8634: phhs-24thiaz-bala-betapyr
8635 : tolhs-ithiadiaz-gly-betadbph8635: tolhs-ithiadiaz-gly-betadbph
8636: ibhs-24thiaz-gly-betaoxaz8636: ibhs-24thiaz-gly-betaoxaz
8637: bhs-25thiaz-gly-betarπpy8637: bhs-25thiaz-gly-betarπpy
8638: phhs-24thiaz-bala-betadtrif8638: phhs-24thiaz-bala-betadtrif
8639: bhs-24thioph-gly-busu2be8639: bhs-24thioph-gly-busu2be
40 8640 : tolhs-ithiadiaz-gly-beta3quin40 8640: tolhs-ithiadiaz-gly-beta3quin
8641 : tolhs-ithiadiaz-bala-betapyee8641: tolhs-ithiadiaz-bala-betapyee
8642: gua-25thiaz-bala-betadcph8642: gua-25thiaz-bala-betadcph
8643 : tolhs-oxadiaz-gly-betapytb8643: tolhs-oxadiaz-gly-betapytb
8644: ibhs-24thiaz-gly-betahbcph 45 8645: ibhs-25methiaz-gly-betadbph8644: ibhs-24thiaz-gly-betahbcph 45 8645: ibhs-25methiaz-gly-betadbph
8646: 2py-24thioph-gly-aspaba8646: 2py-24thioph-gly-aspaba
8647 : ibhs-25thiaz-gly-betahni 8648: ibhs-oxadiaz-bala-betacph 8649: bhs-25thiaz-gly-betacbph 8650: 2py-42oxaz-leu-psdap 8651: bhs-nme35pyr-gly-betahcbph 8652: tolhs-25thiaz-bala-betambiph 8653: phhs-oxadiaz-gly-betapych 8654 : bhs-25methiaz-bala-betadcph 8655 : tolhs-ithiadiaz-gly-betatos 8656: bhs-me25oxaz-gly-betadcph 8657: phhs-oxadiaz-gly-zdapch8647: ibhs-25thiaz-gly-betahni 8648: ibhs-oxadiaz-bala-betacph 8649: bhs-25thiaz-gly-betacbph 8650: 2py-42oxaz-leu-psdap 8651: bhs-nme35pyr-gly-betahcbph 8652: tolhs-25thiaz-bala-betambiphs 8653iaz: ph -gly-betapych 8654: bhs-25methiaz-bala-betadcph 8655: tolhs-ithiadiaz-gly-betatos 8656: bhs-me25oxaz-gly-betadcph 8657: phhs-oxadiaz-gly-zdapch
10 8658 : tolhs-oxadiaz-bala-betafbph 8659: bim-me25thioph-gly-psdap 8660: 2py-24thioph-bala-suabu 8661: 2pmhs-24thioph-phe-zdap 8662: bim-24oxaz-leu-betapy10 8658: tolhs-oxadiaz-bala-betafbph 8659: bim-me25thioph-gly-psdap 8660: 2py-24thioph-bala-suabu 8661: 2 pmhs-24thioph-phe-zdap 8662: bim-24oxaz-leu-betapy
15 8663: bhs-25oxaz-bala-betapbiph 8664: ibhs-25methiaz-gly-betafph 8665 : phhs-25thiaz-gly-betathioph 8666 : tolhs-24thioph-gly-betatbuph 8667: gua-26py-gly-betaibph15 8663: bhs-25oxaz-bala-betapbiph 8664: ibhs-25methiaz-gly-betafph 8665: phhs-25thiaz-gly-betathioph 8666: tolhs-24thioph-gly-betatbuph 8667: gua-26py-gly-betaibph
20 8668: ibhs-24thiaz-bala-betabmph 8669: phhs-ithiadiaz-gly-psdaptb 8670 : phhs-nme35pyr-gly-beta23meoph 8671: bhs-25thiaz-bala-betampy 8672: ibhs-25thiaz-bala-psdapee 8673: 2pmhs-25thiaz-bala-betahph20 8668: ibhs-24thiaz-bala-betabmph 8669: phhs-ithiadiaz-gly-psdaptb 8670: phhs-nme35pyr-gly-beta23meoph 8671: bhs-25thiaz-bala-betampy 8672: ibhs-25thiaz-bala-psdapee 8673: 2 pmh 25thiaz-bala-betahph
25 8674: 2py-53pyrazo-bala-psdap 8675 : bhs-oxadiaz-gly-betabnaphth 8676: 2py-42oxaz-bala-psdap 8677: bim-24thioph-phg-zdap 8678: tolhs-25thiaz-gly-betahmo25 8674: 2py-53pyrazo-bala-psdap 8675: bhs-oxadiaz-gly-betabnaphth 8676: 2py-42oxaz-bala-psdap 8677: bim-24thioph-phg-zdap 8678: tolhs-25thiaz-gly-betahmo
30 8679: bhs-24thiaz-nmgly-betadmoph 8680: phhs-nme35pyr-gly-betaet 8681 : phhs-24thioph-bala-betapyee 8682 : phhs-ithiadiaz-gly-beta34meoph 8683: bhs-42py-ala-zdap30 8679: bhs-24thiaz-nmgly-betadmoph 8680: phhs-nme35pyr-gly-betaet 8681: phhs-24thioph-bala-betapyee 8682: phhs-ithiadiaz-gly-beta34meoph 8683: bhs-42py-ala-zdap
35 8684: bhs-24oxaz-ala-psdap 8685: impy-42nmeim-gly-beta4bph 8686: 2py-25thiaz-ala-betapy 8687: bim-me24oxaz-gly-psdap 8688: bhs-24thioph-gly-betabdimo 8689: tolhs-nme35pyr-bala-ibsdap35 8684: bhs-24oxaz-ala-psdap 8685: impy-42nmeim-gly-beta4bph 8686: 2py-25thiaz-ala-betapy 8687: bim-me24oxaz-gly-psdap 8688: bhs-24thioph-gly-betabdimo 8689: tolhs- nme35pyr-bala-ibsdap
40 8690: gua-25thiaz-gly-betathiobe 8691: phhs-24thiaz-bala-beta35dbph 8692: 3pmhs-25oxaz-gly-betadcph 8693: phhs-24thioph-gly-betaheph 8694: dhim-26py-leu-zdap40 8690: gua-25thiaz-gly-betathiobe 8691: phhs-24thiaz-bala-beta35dbph 8692: 3 pmhs-25oxaz-gly-betadcph 8693: phhs-24thioph-gly-betaheph 8694: dhim-26py-leu-zdap
45 8695: phhs-24thioph-gly-betathiome 8696: bhs-35thioph-ala-zdap 8697: bim-42oxaz-gly-betadcph 8698: phhs-25methiaz-gly-betafph 8699 : bhs-ithiadiaz-bala-betaphethio 8700 : phhs-nme35pyr-bala-betamethioph 8701: phhs-25thiaz-gly-betabph 8702: ibhs-24thioph-gly-betafluo 8703: bhs-25methiaz-bala-zdapee 8704: phhs-ithiadiaz-gly-betahmofu 8705: bhs-24thioph-gly-betathio3 8706: bhs-25thioph-bala-zdap 8707 : phhs-24thioph-bala-betapytb45 8695: phhs-24thioph-gly-betathiome 8696: bhs-35thioph-ala-zdap 8697: bim-42oxaz-gly-betadcph 8698: phhs-25methiaz-gly-betafph 8699: bhs-ithiadiaz-bala-betaphethio 8700: phhs-nme35pyr-bala-betamethioph 8701: phhs-25thiaz-gly-betabph 8702: ibhs-24thioph-gly-betafluo 8703iaz: -bala-zdapee 8704: phhs-ithiadiaz-gly-betahmofu 8705: bhs-24thioph-gly-betathio3 8706: bhs-25thioph-bala-zdap 8707: phhs-24thioph-bala-betapytb
10 8708: phhs-24thiaz-bala-betatos 8709: phhs-nme35pyr-bala-betahb 8710 : bhs-24thiaz-gly-betaomebendi 8711 : phhs-nme35pyr-bala-betal3bendi 8712 : tolhs-25methiaz-bala-betafu310 8708: phhs-24thiaz-bala-betatos 8709: phhs-nme35pyr-bala-betahb 8710: bhs-24thiaz-gly-betaomebendi 8711: phhs-nme35pyr-bala-betal3bendi 8712: tolhs-25methiaz-bala-betafu
15 8713: bhs-thiadiaz-bala-betadcph 8714: phhs-25thiaz-bala-betathiobe 8715: tolhs-me25thiaz-bala-betapy 8716: phhs-oxadiaz-gly-betadhbfu 8717: tolhs-oxadiaz-bala-betah35dc15 8713: bhs-thiadiaz-bala-betadcph 8714: phhs-25thiaz-bala-betathiobe 8715: tolhs-me25thiaz-bala-betapy 8716: phhs-oxadiaz-gly-betadhbfu 8717: tolhs-oxadiaz-bala-betah35dc
20 8718: bim-24thioph-bala-betacph 8719: bim-me25oxaz-gly-zdap 8720: tolhs-me25thiaz-ala-beta34meoph 8721: ibhs-24thiaz-gly-zdapch 8722: bhs-ithiadiaz-gly-betahdbph 8723: bhs-24thioph-gly-betaamibe20 8718: bim-24thioph-bala-betacph 8719: bim-me25oxaz-gly-zdap 8720: tolhs-me25thiaz-ala-beta34meoph 8721: ibhs-24thiaz-gly-zdapch 8722: bhs-ithiadiaz-gly-betahdbph 8723: bhs- 24thioph-gly-betaamibe
25 8724: bhs-25oxaz-gly-betabdimo 8725 : 2py-me25oxaz-gly-psdap 8726 : gua-25thiaz-gly-betabediox 8727: phhs-24thioph-bala-suabu 8728: bhs-24thioph-ala-betadmoph25 8724: bhs-25oxaz-gly-betabdimo 8725: 2py-me25oxaz-gly-psdap 8726: gua-25thiaz-gly-betabediox 8727: phhs-24thioph-bala-suabu 8728: bhs-24thioph-ala-betadmoph
30 8729: 2py-nme35pyr-leu-zdap30 8729: 2py-nme35pyr-leu-zdap
8730 : tolhs-ithiadiaz-bala-busu2be8730: tolhs-ithiadiaz-bala-busu2be
8731: tolhs-nme35pyr-gly-betahph8731: tolhs-nme35pyr-gly-betahph
8732: 2py-25oxaz-gly-psdap8732: 2py-25oxaz-gly-psdap
8733 : ibhs-25methiaz-gly-betafluo8733: ibhs-25methiaz-gly-betafluo
35 8734: bhs-25thiaz-bala-betabediox35 8734: bhs-25thiaz-bala-betabediox
8735: impy-25thiaz-gly-betabthioph8735: impy-25thiaz-gly-betabthioph
8736: bhs-24thiaz-ala-betahph8736: bhs-24thiaz-ala-betahph
8737 : tolhs-me25thioph-bala-beta34meoph8737: tolhs-me25thioph-bala-beta34meoph
8738: gua-26py-gly-betathioph8738: gua-26py-gly-betathioph
8739 : ibhs-24thioph-bala-betabnaphth8739: ibhs-24thioph-bala-betabnaphth
40 8740: tolhs-24thiaz-gly-betahmo40 8740: tolhs-24thiaz-gly-betahmo
8741 : tolhs-ithiadiaz-gly-beta23meoph8741: tolhs-ithiadiaz-gly-beta23meoph
8742 : phhs-25methiaz-bala-betafu38742: phhs-25methiaz-bala-betafu3
8743 : phhs-24thioph-bala-betaomebendi8743: phhs-24thioph-bala-betaomebendi
8744: bim-24thiaz-bala-betaipro8744: bim-24thiaz-bala-betaipro
45 8745: tolhs-me24oxaz-ala-betapy 8746: 2pmhs-25thiaz-gly-betafph 8747: ibhs-oxadiaz-bala-betabenfu 8748: bim-25methiaz-gly-betadbph45 8745: tolhs-me24oxaz-ala-betapy 8746: 2 pmhs-25thiaz-gly-betafph 8747: ibhs-oxadiaz-bala-betabenfu 8748: bim-25methiaz-gly-betadbph
8749: phhs-25methiaz-bala-betabediox8749: phhs-25methiaz-bala-betabediox
8750 : tolhs-ithiadiaz-gly-betahdcph8750: tolhs-ithiadiaz-gly-betahdcph
8751: bhs-25thiaz-leu-betadcph 5 8752: phhs-oxadiaz-bala-zdaptb8751: bhs-25thiaz-leu-betadcph 5 8752: phhs-oxadiaz-bala-zdaptb
8753 : phhs-ithiadiaz-bala-betadtrif8753: phhs-ithiadiaz-bala-betadtrif
8754: bhs-42oxaz-leu-psdap8754: bhs-42oxaz-leu-psdap
8755 : phhs-oxadiaz-gly-betaanaphth8755: phhs-oxadiaz-gly-beta-anaphth
8756: ibhs-25thiaz-gly-betathio38756: ibhs-25thiaz-gly-betathio3
8757: bhs-24thiaz-bala-psdapee8757: bras-24thiaz-bala-psdapee
1010
8758: bhs-25oxaz-bala-betaimid8758: bhs-25oxaz-bala-betaimide
8759: phhs-25thiaz-bala-betadcphtb8759: phhs-25thiaz-bala-betadcphtb
8760: 2py-triaz-bala-psdap8760: 2py-triaz-bala-psdap
8761 : tolhs-25methiaz-gly-betahcbph8761: tolhs-25methiaz-gly-betahcbph
8762: bhs-ithiadiaz-bala-betameph 15 8763: bim-24thioph-ala-betapy8762: bhs-ithiadiaz-bala-betameph 15 8763: bim-24thioph-ala-betapy
8764: bhs-25oxaz-gly-betaphethioa8764: bhs-25oxaz-gly-betaphethioa
8765: bim-24thiaz-gly-betahmph8765: bim-24thiaz-gly-betahmph
8766 : phhs-25methiaz-gly-betadcphch8766: phhs-25methiaz-gly-betadcphch
8767 : ibhs-24thioph-bala-betafluo 20 8768: tolhs-24thiaz-gly-betapym8767: ibhs-24thioph-bala-betafluo 20 8768: tolhs-24thiaz-gly-betapym
8769: bhs-24thioph-gly-betahcbph8769: bhs-24thioph-gly-betahcbph
8770: ibhs-nme35pyr-gly-betahc8770: ibhs-nme35pyr-gly-betahc
8771: 2py-me25thioph-ala-betapy8771: 2py-me25thioph-ala-betapy
8772: 2py-53pyrazo-bala-zdap8772: 2py-53pyrazo-bala-zdap
8773: ibhs-oxadiaz-bala-betafu28773: ibhs-oxadiaz-bala-betafu2
25 8774: ibhs-25oxaz-gly-zdapee25 8774: ibhs-25oxaz-gly-zdapee
8775: phhs-25thiaz-gly-betapytb8775: phhs-25thiaz-gly-betapytb
8776: ibhs-25oxaz-bala-beta34dcph8776: ibhs-25oxaz-bala-beta34dcph
8777 : tolhs-25oxaz-bala-betaphethio8777: tolhs-25oxaz-bala-betaphethio
8778: bhs-oxadiaz-bala-psdapee 30 8779: tolhs-oxadiaz-gly-betahdbph8778: bhs-oxadiaz-bala-psdapee 30 8779: tolhs-oxadiaz-gly-betahdbph
8780: 2py-25methiaz-gly-betapy8780: 2py-25methiaz-gly-betapy
8781: ibhs-24thiaz-gly-betahcbph8781: ibhs-24thiaz-gly-betahcbph
8782: bhs-25methiaz-gly-betafbph8782: bhs-25methiaz-gly-betafbph
8783: phhs-24thiaz-gly-betahb 35 8784: 2pmhs-24thioph-bala-zdap8783: phhs-24thiaz-gly-betahb 35 8784: 2 pmhs-24thioph-bala-zdap
8785: phhs-24thiaz-bala-betabdimo8785: phhs-24thiaz-bala-betabdimo
8786 : tolhs-nme35pyr-bala-betaoxaz8786: tolhs-nme35pyr-bala-betaoxaz
8787: hts-25methiaz-gly-betapy8787: hts-25methiaz-gly-betapy
8788: phhs-me25thioph-bala-beta34meoph8788: phhs-me25thioph-bala-beta34meoph
8789: bhs-24thiaz-gly-betadhbfu8789: bhs-24thiaz-gly-betadhbfu
40 8790: gua-25thioph-gly-betafu340 8790: gua-25thioph-gly-betafu3
8791 : 2pmhs-24thiaz-bala-betal3bendi8791: 2 pmhs-24thiaz-bala-betal3bendi
8792: bhs-oxadiaz-gly-beta4bph8792: bhs-oxadiaz-gly-beta4bph
8793 : ibhs-24thiaz-gly-betal3bendi8793: ibhs-24thiaz-gly-betal3bendi
8794 : ibhs-25methiaz-gly-betaoxaz 45 8795: tolhs-oxadiaz-gly-betal3bendi8794: ibhs-25methiaz-gly-betaoxaz 45 8795: tolhs-oxadiaz-gly-betal3bendi
8796: ibhs-24thiaz-bala-busu2be8796: ibhs-24thiaz-bala-busu2be
8797 : bim-me24 hiaz-ala-beta34meoph 8798: phhs-ithiadiaz-bala-betacthioph 8799: bim-24thioph-gly-psdap 8800: 2pmhs-25oxaz-hphe-betadcph 8801: bhs-me24thioph-bala-betapy 8802: ibhs-24thiaz-gly-psdaptb 8803 : bhs-24thiaz-gly-betacthioph 8804 : phhs-oxadiaz-bala-betathioph 8805: bim-24oxaz-gly-betameph 8806: phhs-nme35pyr-bala-betahdcph 8807: bim-24thiaz-bala-aspibua8797: bim-me24 hiaz-ala-beta34meoph 8798: phhs-ithiadiaz-bala-betacthioph 8799: bim-24thioph-gly-psdap 8800: 2 pmhs-25oxaz-hphe-betadcph 8801: bhs-me24thioph-bala-betapy 8802: ibhs-24thiaz-gly-psdaptb-24803iaz: bhs -gly-betacthioph 8804: phhs-oxadiaz-bala-betathioph 8805: bim-24oxaz-gly-betameph 8806: phhs-nme35pyr-bala-betahdcph 8807: bim-24thiaz-bala-aspibua
10 8808: 2py-nme35pyr-ala-zdap 8809: dhim-24oxaz-ala-psdap 8810: tolhs-25oxaz-gly-beta35dbph 8811 : tolhs-25methiaz-bala-zdaptb 8812 : bhs-oxadiaz-gly-betafu210 8808: 2py-nme35pyr-ala-zdap 8809: dhim-24oxaz-ala-psdap 8810: tolhs-25oxaz-gly-beta35dbph 8811: tolhs-25methiaz-bala-zdaptb 8812: bhs-oxadiaz-gly-betafu2
15 8813: bhs-oxadiaz-bala-beta34dcph 8814 : tolhs-25thiaz-gly-betadtrif 8815: tolhs-24thiaz-gly-betaomebendi 8816 : tolhs-me24thioph-gly-betapy 8817: bhs-25methiaz-gly-aspbzla15 8813: bhs-oxadiaz-bala-beta34dcph 8814: tolhs-25thiaz-gly-betadtrif 8815: tolhs-24thiaz-gly-betaomebendi 8816: tolhs-me24thioph-gly-betapy 8817: bhs-25methiaz-gly-aspbzla
20 8818: tolhs-24thioph-bala-betaanaphth 8819 : ibhs-25methiaz-bala-betameph 8820: 2py-24im-leu-betapy 8821: bhs-25thiaz-gly-beta35dbph 8822 : bim-42nmeim-gly-betadcph 8823 : tolhs-me24thiaz-bala-betaph20 8818: tolhs-24thioph-bala-betaanaphth 8819: ibhs-25methiaz-bala-betameph 8820: 2py-24im-leu-betapy 8821: bhs-25thiaz-gly-beta35dbph 8822: bim-42nmeim-gly-betadcph 8823: tolhs- me24thiaz-bala-betaph
25 8824: bhs-me24thiaz-leu-betaph 8825: bhs-25methiaz-gly-psdapch 8826: phhs-me25oxaz-leu-betadcph 8827: 2py-me25oxaz-ala-zdap 8828: phhs-24thiaz-bala-psdapch25 8824: bhs-me24thiaz-leu-betaph 8825: bhs-25methiaz-gly-psdapch 8826: phhs-me25oxaz-leu-betadcph 8827: 2py-me25oxaz-ala-zdap 8828: phhs-24thiaz-bala-psdapch
30 8829: phhs-24thiaz-bala-psdaptb30 8829: phhs-24thiaz-bala-psdaptb
8830 : phhs-24thioph-gly-betacthioph 8831: ibhs-ithiadiaz-gly-betabmph 8832: bim-24oxaz-ala-betameph 8833: ibhs-25methiaz-bala-betahph8830: phhs-24thioph-gly-betacthioph 8831: ibhs-ithiadiaz-gly-betabmph 8832: bim-24oxaz-ala-betameph 8833: ibhs-25methiaz-bala-betahph
35 8834: tolhs-25oxaz-gly-betadcph 8835: ibhs-nme35pyr-bala-betahmo 8836 : ibhs-ithiadiaz-bala-psdapee 8837: ibhs-25oxaz-bala-betabph 8838: bhs-oxadiaz-gly-beta3quin 8839 : phhs-25oxaz-gly-betaamibe35 8834: tolhs-25oxaz-gly-betadcph 8835: ibhs-nme35pyr-bala-betahmo 8836: ibhs-ithiadiaz-bala-psdapee 8837: ibhs-25oxaz-bala-betabph 8838: bhs-oxadiaz-gly-beta3quin 8839: phhs- 25oxaz-gly-betaamibe
40 8840: tolhs-25thiaz-gly-aspbzla 8841 : phhs-nme35pyr-gly-beta35dbph 8842: 2py-25methiaz-ala-zdap 8843 : tolhs-24thiaz-bala-betapyr 8844: bhs-24thiaz-bala-betabenfu40 8840: tolhs-25thiaz-gly-aspbzla 8841: phhs-nme35pyr-gly-beta35dbph 8842: 2py-25methiaz-ala-zdap 8843: tolhs-24thiaz-bala-betapyr 8844: bhs-24thiaz-bala-betabenfu
45 8845: ibhs-nme35pyr-gly-betafu3 8846 : ibhs-ithiadiaz-gly-betadtrif 8847: tolhs-24thioph-gly-zdapch 8848 : phhs-me25thioph-bala-betapy 8849: 2py-25thiaz-ala-zdap 8850 : phhs-ithiadiaz-bala-betaipro 8851: bim-me25oxaz-ala-betaph 8852 : ibhs-24thiaz-bala-betadcphee 8853: phhs-25methiaz-bala-betambiph 8854 : tolhs-ithiadiaz-bala-betafph 8855: phhs-25thiaz-bala-betadito 8856: 4pmhs-26py-gly-psdap 8857: bhs-25thiaz-nmgly-betahph45 8845: ibhs-nme35pyr-gly-betafu3 8846: ibhs-ithiadiaz-gly-betadtrif 8847: tolhs-24thioph-gly-zdapch 8848: phhs-me25thioph-bala-betapy 8849: 2py-25thiaz-ala-zdap 8850: phhs-ithiadiaz-bala-betaipro 8851: bim-me25oxaz-ala-betaph 8852: ibhs-24thiaz-bala-betadcphee 8853: phhs 25meth -bala-betambiph 8854: tolhs-ithiadiaz-bala-betafph 8855: phhs-25thiaz-bala-betadito 8856: 4 pmhs-26py-gly-psdap 8857: bhs-25thiaz-nmgly-betahph
10 8858 : tolhs-24thioph-bala-betabpy 8859: phhs-24thiaz-gly-betatbuph 8860: phhs-25thiaz-gly-betabenfu 8861: bhs-25oxaz-gly-betaftrif 8862: phhs-25oxaz-gly-betaimid10 8858: tolhs-24thioph-bala-betabpy 8859: phhs-24thiaz-gly-betatbuph 8860: phhs-25thiaz-gly-betabenfu 8861: bhs-25oxaz-gly-betaftrif 8862: phhs-25oxaz-gly-betaimid
15 8863: phhs-25oxaz-bala-betacph15 8863: phhs-25oxaz-bala-betacph
8864 : tolhs-25thiaz-bala-betabnaphth 8865: bhs-25thioph-gly-betadcph 8866: bhs-24oxaz-gly-zdap 8867: bhs-25thioph-gly-betameph8864: tolhs-25thiaz-bala-betabnaphth 8865: bhs-25thioph-gly-betadcph 8866: bhs-24oxaz-gly-zdap 8867: bhs-25thioph-gly-betameph
20 8868: phhs-nme35pyr-bala-betainyl 8869: phhs-me25thiaz-bala-psdap 8870 : tolhs-25oxaz-bala-betathio3 8871: impy-25thiaz-bala-betafu3 8872: bim-25methiaz-phg-zdap 8873: phhs-24thiaz-bala-betadcph20 8868: phhs-nme35pyr-bala-betainyl 8869: phhs-me25thiaz-bala-psdap 8870: tolhs-25oxaz-bala-betathio3 8871: impy-25thiaz-bala-betafu3 8872: bim-25methiaz-phg-zdap 8873: phhs- 24thiaz-bala-betadcph
25 8874: tolhs-24thiaz-gly-zdapch 8875: phhs-25methiaz-gly-zdaptb 8876 : bhs-24thiaz-nmgly-beta23meoph 8877: tolhs-me25oxaz-leu-zdap 8878: gua-25thioph-gly-betahni25 8874: tolhs-24thiaz-gly-zdapch 8875: phhs-25methiaz-gly-zdaptb 8876: bhs-24thiaz-nmgly-beta23meoph 8877: tolhs-me25oxaz-leu-zdap 8878: gua-25thioph-gly-betahni
30 8879: tolhs-25thiaz-bala-betahph 8880: ibhs-25oxaz-gly-betaph 8881 : bhs-ithiadiaz-bala-betadcph 8882 : tolhs-25methiaz-gly-betabdimo 8883: phhs-nme35pyr-gly-betapbiph30 8879: tolhs-25thiaz-bala-betahph 8880: ibhs-25oxaz-gly-betaph 8881: bhs-ithiadiaz-bala-betadcph 8882: tolhs-25methiaz-gly-betabdimo 8883: phhs-nme35pyr-gly-betapbiph
35 8884: bhs-25thiaz-gly-suabu 8885: bim-me25oxaz-ala-betapy 8886: phhs-25oxaz-gly-betathiome 8887: impy-24thiaz-gly-betahmofu 8888 : tolhs-nme35pyr-gly-betadcphtb 8889: gua-26py-gly-betaphethioa35 8884: bhs-25thiaz-gly-suabu 8885: bim-me25oxaz-ala-betapy 8886: phhs-25oxaz-gly-betathiome 8887: impy-24thiaz-gly-betahmofu 8888: tolhs-nme35pyr-gly-betadcphtb 8889: gua- 26py-gly-betaphethioa
40 8890: 2py-oxadiaz-bala-betadcph 8891 : tolhs-nme35pyr-gly-betadcphee 8892: tolhs-nme35pyr-bala-betaipr 8893 : tolhs-me25thioph-leu-betaph 8894: 2py-24im-bala-betadcph 45 8895: ibhs-24thiaz-gly-betatos 8896: ibhs-25thiaz-gly-betaipro 8897: gua-25thioph-gly-betadbph 8898 : tolhs-ithiadiaz-bala-betabmph 8899: tolhs-25methiaz-gly-betampy 8900: phhs-nme35pyr-gly-betafbph 8901: 2py-25fur-ala-zdap 8902 : ibhs-24thioph-bala-betahmofu 8903 : tolhs-24thiaz-bala-betaftrif 8904: bhs-25methiaz-gly-betaheph 8905: phhs-25methiaz-gly-aspibua 8906: bim-24thiaz-bala-betahcbph 8907: 2py-25thioph-ala-psdap40 8890: 2py-oxadiaz-bala-betadcph 8891: tolhs-nme35pyr-gly-betadcphee 8892: tolhs-nme35pyr-bala-betaipr 8893: tolhs-me25thioph-leu-betaph 8894: 2py-24im-bala-betadch -24thiaz-gly-betatos 8896: ibhs-25thiaz-gly-betaipro 8897: gua-25thioph-gly-betadbph 8898: tolhs-ithiadiaz-bala-betabmph 8899: tolhs-25methiaz-gly-betampy 8900: phhs-nme35pyr-gly-betafbph 8901: 2py-25fur-ala-zdap 8902: ibhs-24thioph-bala-betahmiazh 8903 -bala-betaftrif 8904: bhs-25methiaz-gly-betaheph 8905: phhs-25methiaz-gly-aspibua 8906: bim-24thiaz-bala-betahcbph 8907: 2py-25thioph-ala-psdap
10 8908: bim-24thioph-leu-betadcph 8909: bhs-nme35pyr-gly-beta34dcph 8910: bhs-ithiadiaz-bala-betapy 8911 : ibhs-nme35pyr-bala-betadmoph 8912: 2py-me24oxaz-leu-zdap10 8908: bim-24thioph-leu-betadcph 8909: bhs-nme35pyr-gly-beta34dcph 8910: bhs-ithiadiaz-bala-betapy 8911: ibhs-nme35pyr-bala-betadmoph 8912: 2py-me24oxaz-leu-zdap
15 8913: tolhs-ithiadiaz-gly-betapyee 8914 : bhs-25oxaz-bala-betabnaphth 8915 : phhs-nme35pyr-bala-betaomebendi 8916: bhs-24thioph-nmgly-betaoxaz 8917: bhs-nme35pyr-gly-betabdimo15 8913: tolhs-ithiadiaz-gly-betapyee 8914: bhs-25oxaz-bala-betabnaphth 8915: phhs-nme35pyr-bala-betaomebendi 8916: bhs-24thioph-nmgly-betaoxaz 8917: bhs-nme35pyr-gly-betabdimo
20 8918: ibhs-nme35pyr-gly-betadcph20 8918: ibhs-nme35pyr-gly-betadcph
8919: bim-25methiaz-bala-betatos8919: bim-25methiaz-bala-betatos
8920: phhs-nme35pyr-bala-beta35dbph8920: phhs-nme35pyr-bala-beta35dbph
8921: bhs-42nmeim-bala-beta3quin8921: bhs-42nmeim-bala-beta3quin
8922 : phhs-oxadiaz-bala-betahdbph8922: phhs-oxadiaz-bala-betahdbph
8923 : ibhs-24thioph-bala-betabenfu 25 . . .8923: ibhs-24thioph-bala-betabenfu 25. . .
8924 : phhs-ιthιadιaz-bala-busu2be8924: phhs-ιthιadιaz-bala-busu2be
8925: bhs-24thiaz-bala-beta34dcph8925: bhs-24thiaz-bala-beta34dcph
8926: sabhs-24oxaz-gly-zdap8926: sabhs-24oxaz-gly-zdap
8927: phhs-25oxaz-gly-betahdbph8927: phhs-25oxaz-gly-betahdbph
8928: bhs-24thiaz-gly-betapyr8928: bhs-24thiaz-gly-betapyr
30 8929: ibhs-ithiadiaz-bala-betabthioph 8930: bhs-nme35pyr-nmgly-betadmoph 8931: ibhs-ithiadiaz-gly-betabph 8932 : tolhs-25methiaz-bala-betapbiph 8933: tolhs-me24oxaz-ala-betaph30 8929: ibhs-ithiadiaz-bala-betabthioph 8930: bhs-nme35pyr-nmgly-betadmoph 8931: ibhs-ithiadiaz-gly-betabph 8932: tolhs-25methiaz-bala-betapbiph 8933: tolhs-me24oxaz-ala-betaph
35 8934: phhs-25thiaz-bala-betadcphee 8935: gua-25thioph-gly-betabenfu 8936: ibhs-nme35pyr-gly-beta34dcph 8937 : bhs-me24thioph-ala-beta34meoph 8938: bhs-25thiaz-nmgly-beta34meoph 8939: phhs-ithiadiaz-gly-betadmoph35 8934: phhs-25thiaz-bala-betadcphee 8935: gua-25thioph-gly-betabenfu 8936: ibhs-nme35pyr-gly-beta34dcph 8937: bhs-me24thioph-ala-beta34meoph 8938: bhs-25thiaz-nmgly-beta34hoph39 ithiadiaz-gly-betadmoph
40 8940: phhs-nme35pyr-bala-zdaptb 8941 : bhs-ithiadiaz-gly-betathioph 8942: gua-24thiaz-gly-betabmph 8943: 2py-24thioph-gly-betapy 8944: bhs-24thiaz-bala-psdap40 8940: phhs-nme35pyr-bala-zdaptb 8941: bhs-ithiadiaz-gly-betathioph 8942: gua-24thiaz-gly-betabmph 8943: 2py-24thioph-gly-betapy 8944: bhs-24thiaz-bala-psdap
45 8945: bhs-24thiaz-gly-betaibph 8946: phhs-oxadiaz-gly-betapbiph 8947: bim-triaz-bala-betadcph 8948: hs-42pym-gly-psdap45 8945: bhs-24thiaz-gly-betaibph 8946: phhs-oxadiaz-gly-betapbiph 8947: bim-triaz-bala-betadcph 8948: hs-42pym-gly-psdap
8949: tolhs-ithiadiaz-bala-suabu8949: tolhs-ithiadiaz-bala-suabu
8950 : tolhs-24thioph-bala-betacbph8950: tolhs-24thioph-bala-betacbph
8951: phhs-me25oxaz-leu-psdap8951: phhs-me25oxaz-leu-psdap
8952: bhs-oxadiaz-gly-beta35dbph8952: bhs-oxadiaz-gly-beta35dbph
8953: phhs-25oxaz-gly-betahph8953: phhs-25oxaz-gly-betahph
8954 : tolhs-me25oxaz-leu-beta34meoph8954: tolhs-me25oxaz-leu-beta34meoph
8955: bhs-oxadiaz-gly-aspibua8955: bras-oxadiaz-gly-aspibua
8956 : tolhs-25methiaz-bala-betabediox8956: tolhs-25methiaz-bala-betabediox
8957: phhs-oxadiaz-gly-psdapee8957: phhs-oxadiaz-gly-psdapee
1010
8958: phhs-nme35pyr-bala-betaipro8958: phhs-nme35pyr-bala-betaipro
8959: bhs-nme35pyr-bala-betahmph8959: bhs-nme35pyr-bala-betahmph
8960: phhs-25oxaz-gly-betabediox8960: phhs-25oxaz-gly-betabediox
8961: bhs-25thiaz-bala-betapych8961: bhs-25thiaz-bala-betapych
8962 : tolhs-25methiaz-gly-betadtrif8962: tolhs-25methiaz-gly-betadtrif
15 8963: bhs-24thioph-leu-psdap 8964: 2py-24im-bala-psdap 8965: bim-42nmeim-gly-betaftrif 8966: bhs-24thioph-bala-betameph 8967 : phhs-ithiadiaz-gly-betaphethioa15 8963: bhs-24thioph-leu-psdap 8964: 2py-24im-bala-psdap 8965: bim-42nmeim-gly-betaftrif 8966: bhs-24thioph-bala-betameph 8967: phhs-ithiadiaz-gly-betaphethioa
2o 8968: 2pmhs-24thioph-bala-betabmph 8969 : phhs-24thiaz-bala-betathiobe 8970 : tolhs-me25thioph-ala-betadcph 8971: bhs-25methiaz-gly-zdapch 8972 : ibhs-25methiaz-bala-betadcphee 8973: phhs-25oxaz-gly-aspibua2o 8968: 2 pmhs-24thioph-bala-betabmph 8969: phhs-24thiaz-bala-betathiobe 8970: tolhs-me25thioph-ala-betadcph 8971: bhs-25methiaz-gly-zdapch 8972: ibhs-25methiaz-bala-betadchhe 89 25oxaz-gly-aspibua
25 8974: tolhs-25thiaz-bala-busu2be 8975 : phhs-24thioph-bala-betaphethio 8976: ibhs-25methiaz-gly-betahph 8977: tolhs-24thioph-bala-betaol 8978: tolhs-25oxaz-gly-betapyee25 8974: tolhs-25thiaz-bala-busu2be 8975: phhs-24thioph-bala-betaphethio 8976: ibhs-25methiaz-gly-betahph 8977: tolhs-24thioph-bala-betaol 8978: tolhs-25oxaz-gly-betapyee
30 8979: ibhs-ithiadiaz-bala-beta35dbph 8980 : bhs-25methiaz-bala-betadcphch 8981: phhs-nme35pyr-bala-betabenfu 8982: phhs-nme35pyr-gly-betadhbfu 8983 : bhs-ithiadiaz-ala-betabpy30 8979: ibhs-ithiadiaz-bala-beta35dbph 8980: bhs-25methiaz-bala-betadcphch 8981: phhs-nme35pyr-bala-betabenfu 8982: phhs-nme35pyr-gly-betadhbfu 8983: bhs-ithiadiaz-ala-betabc
35 8984: ibhs-24thioph-gly-betahph 8985: 2py-me25thiaz-ala-betapy 8986: bim-53pyrazo-ala-psdap 8987: 2py-nme35pyr-bala-zdap 8988 : 2py-nme35pyr-gly-aspaba 8989: bhs-oxadiaz-bala-betahdbph35 8984: ibhs-24thioph-gly-betahph 8985: 2py-me25thiaz-ala-betapy 8986: bim-53pyrazo-ala-psdap 8987: 2py-nme35pyr-bala-zdap 8988: 2py-nme35pyr-gly-aspaba 8989: bhs- oxadiaz-bala-betahdbph
40 8990: bhs-oxadiaz-gly-betaol 8991: ibhs-25oxaz-bala-betahb 8992: tolhs-25oxaz-gly-ibsdap 8993: tolhs-nme35pyr-gly-asppha 8994: phhs-25oxaz-gly-betafph40 8990: bhs-oxadiaz-gly-betaol 8991: ibhs-25oxaz-bala-betahb 8992: tolhs-25oxaz-gly-ibsdap 8993: tolhs-nme35pyr-gly-asppha 8994: phhs-25oxaz-gly-betafph
45 8995: bhs-25oxaz-ala-betadmoph 8996: bim-ithiadiaz-bala-psdap 8997: bhs-me25oxaz-leu-zdap 8998: ibhs-25thiaz-bala-busu2be 8999: bim-me24thioph-leu-psdap 9000: bhs-me25thioph-ala-zdap 9001: phhs-oxadiaz-bala-betahmo 9002 : bhs-ithiadiaz-bala-betafluo 9003: bhs-25methiaz-bala-betafph 9004: bhs-53pyrazo-gly-zdap 9005: bhs-ithiadiaz-gly-betah35dc 9006: tolhs-25methiaz-gly-csdap 9007: phhs-me25thiaz-leu-zdap45 8995: bhs-25oxaz-ala-betadmoph 8996: bim-ithiadiaz-bala-psdap 8997: bhs-me25oxaz-leu-zdap 8998: ibhs-25thiaz-bala-busu2be 8999: bim-me24thioph-leu-psdap 9000: bhs-me25thioph-ala-zdap 9001: phhs-oxadiaz-bala-betahmo 9002: bhs-ithiadiaz-bala-betafluo 9003meth: bhs -bala-betafph 9004: bhs-53pyrazo-gly-zdap 9005: bhs-ithiadiaz-gly-betah35dc 9006: tolhs-25methiaz-gly-csdap 9007: phhs-me25thiaz-leu-zdap
10 9008: ibhs-nme35pyr-gly-betaet 9009: bhs-oxadiaz-ala-beta3quin 9010: phhs-24thiaz-bala-betaol 9011 : bhs-25methiaz-gly-betatbuph 9012: bhs-25thiaz-gly-psdap10 9008: ibhs-nme35pyr-gly-betaet 9009: bhs-oxadiaz-ala-beta3quin 9010: phhs-24thiaz-bala-betaol 9011: bhs-25methiaz-gly-betatbuph 9012: bhs-25thiaz-gly-psdap
15 9013: tolhs-me24thioph-gly-psdap 9014: tolhs-nme35pyr-gly-betadbph 9015: bhs-24thioph-gly-betabediox 9016: tolhs-25methiaz-gly-aspaba 9017 : 2pmhs-25methiaz-gly-betadtrif15 9013: tolhs-me24thioph-gly-psdap 9014: tolhs-nme35pyr-gly-betadbph 9015: bhs-24thioph-gly-betabediox 9016: tolhs-25methiaz-gly-aspaba 9017: 2 pmhs-25methiaz-gly-betadtrif
20 9018: ibhs-25oxaz-bala-betahdcph 9019: bim-oxadiaz-gly-asppha 9020: phhs-nme35pyr-bala-beta4bph 9021: bhs-25oxaz-ala-betahmph 9022: tolhs-25oxaz-bala-betahni 9023: phhs-me24oxaz-ala-psdap20 9018: ibhs-25oxaz-bala-betahdcph 9019: bim-oxadiaz-gly-asppha 9020: phhs-nme35pyr-bala-beta4bph 9021: bhs-25oxaz-ala-betahmph 9022: tolhs-25oxaz-bala-betahni 9023: phhs- me24oxaz-ala-psdap
25 9024: bhs-42nmeim-gly-zdap 9025: phhs-25methiaz-gly-betahmo 9026: bhs-24thiaz-nmgly-betapy 9027: ibhs-24thiaz-bala-zdaptb 9028: bim-35thioph-bala-betadcph25 9024: bhs-42nmeim-gly-zdap 9025: phhs-25methiaz-gly-betahmo 9026: bhs-24thiaz-nmgly-betapy 9027: ibhs-24thiaz-bala-zdaptb 9028: bim-35thioph-bala-betadcph
30 9029: ibhs-ithiadiaz-gly-betaipr 9030: bhs-25thiaz-bala-aspibua 9031: phhs-25oxaz-gly-betadcphch 9032: 2py-me25thiaz-gly-psdap 9033: ibhs-25thiaz-bala-beta3quin30 9029: ibhs-ithiadiaz-gly-betaipr 9030: bhs-25thiaz-bala-aspibua 9031: phhs-25oxaz-gly-betadcphch 9032: 2py-me25thiaz-gly-psdap 9033: ibhs-25thiaz-bala-beta3quin
35 9034: bhs-25thiaz-leu-zdap35 9034: bhs-25thiaz-leu-zdap
9035: dhthi-24thioph-bala-betadcph 9036: ibhs-oxadiaz-gly-psdapch 9037: ibhs-25oxaz-bala-zdaptb 9038: tolhs-25oxaz-gly-betaimid 9039: bhs-ithiadiaz-bala-betahc9035: dhthi-24thioph-bala-betadcph 9036: ibhs-oxadiaz-gly-psdapch 9037: ibhs-25oxaz-bala-zdaptb 9038: tolhs-25oxaz-gly-betaimid 9039: bhs-ithiadiaz-bala-betahc
40 9040: bhs-oxadiaz-gly-betampy 9041: bhs-me24thiaz-bala-psdap 9042: tolhs-24thiaz-gly-psdap 9043: phhs-25thiaz-bala-betapym 9044: bim-ithiadiaz-gly-betapy40 9040: bhs-oxadiaz-gly-betampy 9041: bhs-me24thiaz-bala-psdap 9042: tolhs-24thiaz-gly-psdap 9043: phhs-25thiaz-bala-betapym 9044: bim-ithiadiaz-gly-betapy
45 9045: bhs-oxadiaz-bala-betainyl 9046: ibhs-25oxaz-bala-betadmph 9047: ibhs-24thiaz-bala-psdaptb 9048: bhs-24thiaz-bala-betadcph45 9045: bhs-oxadiaz-bala-betainyl 9046: ibhs-25oxaz-bala-betadmph 9047: ibhs-24thiaz-bala-psdaptb 9048: bras-24thiaz-bala-betadcph
9049: bhs-24thiaz-gly-beta34dcph9049: bhs-24thiaz-gly-beta34dcph
9050: bhs-ithiadiaz-gly-zdap9050: bhs-ithiadiaz-gly-zdap
9051: agua-24thiaz-gly-psdap 5 9052: 2py-24thioph-leu-zdap9051: agua-24thiaz-gly-psdap 5 9052: 2py-24thioph-leu-zdap
9053 : phhs-24thioph-gly-betatbuph9053: phhs-24thioph-gly-betatbuph
9054: ibhs-25oxaz-gly-betadhbfu9054: ibhs-25oxaz-gly-betadhbfu
9055: bhs-ithiadiaz-gly-betahni9055: bhs-ithiadiaz-gly-betahni
9056 : 2py-24thioph-bala-betabnaphth9056: 2py-24thioph-bala-betabnaphth
9057: gua-26py-gly-betahni9057: gua-26py-gly-betahni
10 9058 : phhs-24thioph-bala-beta34meoph10 9058: phhs-24thioph-bala-beta34meoph
9059: bhs-25methiaz-gly-betadbph9059: bhs-25methiaz-gly-betadbph
9060: bhs-triaz-leu-betapy9060: bras-triaz-leu-betapy
9061: bhs-ithiadiaz-gly-betaimid9061: bhs-ithiadiaz-gly-betaimide
9062: ibhs-24thiaz-gly-betaamibe 15 9063: gua-24thiaz-gly-betahph9062: ibhs-24thiaz-gly-betaamibe 15 9063: gua-24thiaz-gly-betahph
9064: phhs-25methiaz-gly-zdapch9064: phhs-25methiaz-gly-zdapch
9065: phhs-oxadiaz-gly-aspaba9065: phhs-oxadiaz-gly-aspaba
9066: bhs-25methiaz-leu-betadcph9066: bras-25methiaz-leu-betadcph
9067 : 2pmhs-25methiaz-bala-betahph 2o 9068: phhs-24thioph-bala-beta3quin9067: 2 pmhs-25methiaz-bala-betahph 2o 9068: phhs-24thioph-bala-beta3quin
9069: dhim-52thiaz-gly-betadcph9069: dhim-52thiaz-gly-betadcph
9070: tolhs-25oxaz-gly-aspibua9070: tolhs-25oxaz-gly-aspibua
9071 : 2py-nme35pyr-bala-aspbzla9071: 2py-nme35pyr-bala-aspbzla
9072: bhs-24thiaz-bala-betahmph9072: bhs-24thiaz-bala-betahmph
9073: tolhs-24thioph-bala-betahmo9073: tolhs-24thioph-bala-betahmo
25 9074: impy-25oxaz-gly-betadhbfu25 9074: impy-25oxaz-gly-betadhbfu
9075: phhs-25thiaz-bala-betapytb9075: phhs-25thiaz-bala-betapytb
9076: bhs-25methiaz-gly-asppha9076: bhs-25methiaz-gly-asppha
9077 : ibhs-24thiaz-bala-betathio39077: ibhs-24thiaz-bala-betathio3
9078: impy-25oxaz-ser-zdap 30 9079: bhs-ithiadiaz-gly-betacph9078: impy-25oxaz-ser-zdap 30 9079: bhs-ithiadiaz-gly-betacph
9080: bhs-24thioph-gly-betadtrif9080: bhs-24thioph-gly-betadtrif
9081: tolhs-me24oxaz-gly-zdap9081: tolhs-me24oxaz-gly-zdap
9082 : phhs-25methiaz-bala-betaipro9082: phhs-25methiaz-bala-betaipro
9083: bhs-24oxaz-bala-betapy 35 9084: bhs-25methiaz-gly-betacthioph9083: bhs-24oxaz-bala-betapy 35 9084: bhs-25methiaz-gly-betacthioph
9085: bhs-25methiaz-ala-betadmph9085: bhs-25methiaz-ala-betadmph
9086: bhs-24thiaz-bala-betathio39086: bhs-24thiaz-bala-betathio3
9087: bhs-nme35pyr-gly-betaet9087: bhs-nme35pyr-gly-betaet
9088: phhs-nme35pyr-bala-betaftrif9088: phhs-nme35pyr-bala-betaftrif
9089: bhs-24thiaz-gly-betadcphch9089: bhs-24thiaz-gly-betadcphch
40 9090 : tolhs-oxadiaz-bala-beta34dcph40 9090: tolhs-oxadiaz-bala-beta34dcph
9091 : tolhs-24thioph-gly-betaoxope9091: tolhs-24thioph-gly-betaoxope
9092: hyd-25methiaz-bala-betameph9092: hyd-25methiaz-bala-betameph
9093: bhs-25oxaz-bala-betapych9093: bras-25oxaz-bala-betapych
9094: phhs-me24thiaz-gly-betapy 45 9095: bhs-24thioph-bala-betahmofu9094: phhs-me24thiaz-gly-betapy 45 9095: bhs-24thioph-bala-betahmofu
9096: ibhs-25thiaz-gly-beta4bph9096: ibhs-25thiaz-gly-beta4bph
9097: tolhs-25thiaz-gly-betadhbfu 9098: tolhs-25oxaz-gly-betaoxaz 9099: 2py-me24oxaz-gly-betapy 9100: ibhs-25oxaz-bala-betapym 9101: bhs-24im-ala-psdap 9102 : ibhs-oxadiaz-bala-betathioph 9103: bim-42nmeim-bala-psdap 9104: bhs-me25oxaz-bala-betaph 9105 : 2py-me24thiaz-bala-betadcph 9106: ibhs-24thiaz-gly-betafluo 9107 : bhs-oxadiaz-gly-betamethioph9097: tolhs-25thiaz-gly-betadhbfu 9098: tolhs-25oxaz-gly-betaoxaz 9099: 2py-me24oxaz-gly-betapy 9100: ibhs-25oxaz-bala-betapym 9101: bhs-24im-ala-psdap 9102: ibhs-oxadiaz-bala-betathioph 9103: bim-42nim -bala-psdap 9104: bhs-me25oxaz-bala-betaph 9105: 2py-me24thiaz-bala-betadcph 9106: ibhs-24thiaz-gly-betafluo 9107: bhs-oxadiaz-gly-betamethioph
10 9108: tolhs-24thiaz-bala-betathiome 9109: 2py-42pym-gly-psdap 9110: bhs-24thioph-bala-betapy 9111: bim-25oxaz-gly-zdap 9112: 2py-24pym-gly-betapy10 9108: tolhs-24thiaz-bala-betathiome 9109: 2py-42pym-gly-psdap 9110: bhs-24thioph-bala-betapy 9111: bim-25oxaz-gly-zdap 9112: 2py-24pym-gly-betapy
15 9113: bim-35fur-gly-zdap15 9113: bim-35fur-gly-zdap
9114: phhs-25methiaz-bala-betafphe 9115: tolhs-25methiaz-bala-betapytb 9116: bim-25thioph-ala-zdap 9117: tolhs-oxadiaz-bala-betahni9114: phhs-25methiaz-bala-betafphe 9115: tolhs-25methiaz-bala-betapytb 9116: bim-25thioph-ala-zdap 9117: tolhs-oxadiaz-bala-betahni
20 9118: 2py-triaz-leu-zdap 9119 : phhs-ithiadiaz-gly-beta23meoph 9120: tolhs-oxadiaz-bala-zdaptb 9121: bhs-triaz-ala-betapy 9122: bim-35thioph-leu-betapy 9123: bhs-25thioph-leu-zdap20 9118: 2py-triaz-leu-zdap 9119: phhs-ithiadiaz-gly-beta23meoph 9120: tolhs-oxadiaz-bala-zdaptb 9121: bhs-triaz-ala-betapy 9122: bim-35thioph-leu-betapy 9123: bhs- 25thioph-leu-zdap
25 9124: tolhs-25oxaz-bala-betadcph 9125: 2py-oxadiaz-gly-aspibua 9126: phhs-oxadiaz-bala-betatos 9127 : phhs-ithiadiaz-gly-betaftrif 9128: bhs-25thiaz-bala-betaphethioa25 9124: tolhs-25oxaz-bala-betadcph 9125: 2py-oxadiaz-gly-aspibua 9126: phhs-oxadiaz-bala-betatos 9127: phhs-ithiadiaz-gly-betaftrif 9128: bhs-25thiaz-bala-betaphethioa
30 9129: phhs-ithiadiaz-gly-psdap 9130: bim-26py-gly-zdap 9131: phhs-oxadiaz-bala-betafphe 9132: gua-42pym-gly-betahdbph 9133: dimethpym-26py-gly-betadcph30 9129: phhs-ithiadiaz-gly-psdap 9130: bim-26py-gly-zdap 9131: phhs-oxadiaz-bala-betafphe 9132: gua-42pym-gly-betahdbph 9133: dimethpym-26py-gly-betadcph
35 9134: phhs-24thiaz-gly-asppha35 9134: phhs-24thiaz-gly-asppha
9135 : tolhs-nme35pyr-gly-betaoxope 9136: bim-me24thiaz-bala-betapy 9137: phhs-oxadiaz-gly-betaamibe 9138 : phhs-nme35pyr-gly-betamethioph 9139: phhs-25oxaz-bala-betafu39135: tolhs-nme35pyr-gly-betaoxope 9136: bim-me24thiaz-bala-betapy 9137: phhs-oxadiaz-gly-betaamibe 9138: phhs-nme35pyr-gly-betamethioph 9139: phhs-25oxaz-bala-betafu3
40 9140 : tolhs-25methiaz-bala-betaamibe 9141: ibhs-ithiadiaz-bala-betaπrpy 9142 : tolhs-oxadiaz-gly-betabnaphth 9143: bhs-25thiaz-gly-zdapee 9144: phhs-24thiaz-gly-betafph40 9140: tolhs-25methiaz-bala-betaamibe 9141: ibhs-ithiadiaz-bala-betaπrpy 9142: tolhs-oxadiaz-gly-betabnaphth 9143: bhs-25thiaz-gly-zdapee 9144: phhs-24thiaz-gly-betafph
45 9145: bhs-25methiaz-ala-betadito 9146: phhs-24thioph-bala-betadmoph 9147: tolhs-25oxaz-gly-betahdcph 9148: tolhs-nme35pyr-gly-betaph 9149 : ibhs-ithiadiaz-gly-betapych 9150 : tolhs-25methiaz-gly-betadcph 9151 : phhs-25oxaz-bala-betathiome 9152 : phhs-ithiadiaz-bala-betabenfu 9153: bhs-25oxaz-gly-betadcphtb 9154: ibhs-25oxaz-gly-betathiobe 9155: bhs-25oxaz-gly-betahdbph 9156: 2py-me24thiaz-leu-zdap 9157: phhs-25oxaz-gly-betahmo45 9145: bhs-25methiaz-ala-betadito 9146: phhs-24thioph-bala-betadmoph 9147: tolhs-25oxaz-gly-betahdcph 9148: tolhs-nme35pyr-gly-betaph 9149: ibhs-ithiadiaz-gly-betapych 9150: tolhs-25methiaz-gly-betadcph 9151: phhs-25oxaz-bala-betathiome 9152: phhs-ithiadiaz-bala-betabenhu 9 253 -gly-betadcphtb 9154: ibhs-25oxaz-gly-betathiobe 9155: bhs-25oxaz-gly-betahdbph 9156: 2py-me24thiaz-leu-zdap 9157: phhs-25oxaz-gly-betahmo
10 9158: thazep-25thiaz-gly-betapy 9159: bhs-42nmeim-hphe-zdap 9160: bim-42oxaz-bala-zdap 9161: phhs-25oxaz-gly-aspbzla 9162: ibhs-25thiaz-gly-betafu310 9158: thazep-25thiaz-gly-betapy 9159: bhs-42nmeim-hphe-zdap 9160: bim-42oxaz-bala-zdap 9161: phhs-25oxaz-gly-aspbzla 9162: ibhs-25thiaz-gly-betafu3
15 9163: ibhs-24 hiaz-bala-asppha15 9163: ibhs-24 hiaz-bala-asppha
9164 : ibhs-ithiadiaz-bala-betadcphtb 9165: tolhs-me24oxaz-gly-betapy 9166: tolhs-24thiaz-gly-betadcphee 9167: tolhs-25thiaz-gly-betathioph9164: ibhs-ithiadiaz-bala-betadcphtb 9165: tolhs-me24oxaz-gly-betapy 9166: tolhs-24thiaz-gly-betadcphee 9167: tolhs-25thiaz-gly-betathioph
20 9168 : bim-24thioph-bala-betahcbph 9169 : ibhs-25methiaz-bala-betambiph 9170: phhs-nme35pyr-gly-betampy 9171 : ibhs-25thiaz-bala-betahdcph 9172: tolhs-25oxaz-bala-asppha 9173: bhs-24thiaz-leu-betadcph20 9168: bim-24thioph-bala-betahcbph 9169: ibhs-25methiaz-bala-betambiph 9170: phhs-nme35pyr-gly-betampy 9171: ibhs-25thiaz-bala-betahdcph 9172: tolhs-25oxaz-bala-asppha 917 24thiaz-leu-betadcph
25 9174: bhs-me24oxaz-ala-psdap 9175: phhs-nme35pyr-gly-betabthioph 9176: gua-26py-gly-betafu3 9177 : 2pmhs-24thioph-bala-betathioph 9178: ibhs-25methiaz-bala-asppha25 9174: bhs-me24oxaz-ala-psdap 9175: phhs-nme35pyr-gly-betabthioph 9176: gua-26py-gly-betafu3 9177: 2 pmhs-24thioph-bala-betathioph 9178: ibhs-25methiaz-bala-asppha
30 9179: phhs-25oxaz-gly-betapych 9180: bhs-24thiaz-phe-betapy 9181: tolhs-25thiaz-bala-betaheph 9182: ibhs-24thiaz-gly-betapyr 9183: bhs-24thiaz-bala-betafluo30 9179: phhs-25oxaz-gly-betapych 9180: bhs-24thiaz-phe-betapy 9181: tolhs-25thiaz-bala-betaheph 9182: ibhs-24thiaz-gly-betapyr 9183: bhs-24thiaz-bala-betafluo
35 9184: bim-25thioph-gly-betainyl 9185 : bhs-me24thiaz-bala-beta34meoph 9186 : bhs-25oxaz-nmgly-betaanaphth 9187: bhs-24thiaz-bala-betahcbph 9188: bhs-nme35pyr-bala-betah35dc 9189: ur-24thiaz-gly-betadcph35 9184: bim-25thioph-gly-betainyl 9185: bhs-me24thiaz-bala-beta34meoph 9186: bhs-25oxaz-nmgly-betaanaphth 9187: bhs-24thiaz-bala-betahcbph 9188: bhs-nme35pyr-bala-bet935 24thiaz-gly-betadcph
40 9190: phhs-25thiaz-gly-zdapch 9191: tolhs-25thiaz-gly-betahmofu 9192 : bhs-25oxaz-nmgly-beta34dcph 9193 : tolhs-oxadiaz-gly-beta4bph 9194 : tolhs-25methiaz-gly-betaol40 9190: phhs-25thiaz-gly-zdapch 9191: tolhs-25thiaz-gly-betahmofu 9192: bhs-25oxaz-nmgly-beta34dcph 9193: tolhs-oxadiaz-gly-beta4bph 9194: tolhs-25methiaz-gly-betaol
45 9195: phhs-24thioph-bala-betapyr 9196: bim-nme35pyr-gly-asppha 9197 : 2py-24thioph-bala-betaoxope 9198: bhs-oxadiaz-bala-betacph45 9195: phhs-24thioph-bala-betapyr 9196: bim-nme35pyr-gly-asppha 9197: 2py-24thioph-bala-betaoxope 9198: bras-oxadiaz-bala-betacph
9199: ibhs-oxadiaz-bala-betacbph9199: ibhs-oxadiaz-bala-betacbph
9200: 2py-me24thiaz-gly-zdap9200: 2py-me24thiaz-gly-zdap
9201: ibhs-24thiaz-bala-betahbcph 5 9202: bhs-24thioph-bala-suabu9201: ibhs-24thiaz-bala-betahbcph 5 9202: bhs-24thioph-bala-suabu
9203: tolhs-24thioph-gly-psdaptb9203: tolhs-24thioph-gly-psdaptb
9204 : phhs-oxadiaz-gly-betahmph9204: phhs-oxadiaz-gly-betahmph
9205: phhs-25methiaz-bala-betaheph9205: phhs-25methiaz-bala-betaheph
9206: ibhs-25methiaz-gly-betadcphee9206: ibhs-25methiaz-gly-betadcphee
9207: bhs-25thiaz-gly-betadcphee9207: bhs-25thiaz-gly-betadcphee
1010
9208: bhs-25thiaz-gly-betal3bendi9208: bhs-25thiaz-gly-betal3bendi
9209 : bhs-24thioph-gly-betal3bendi9209: bhs-24thioph-gly-betal3bendi
9210: bhs-25thiaz-gly-betamethioph9210: bhs-25thiaz-gly-betamethioph
9211: 2py-me24oxaz-bala-zdap9211: 2py-me24oxaz-bala-zdap
9212 : 2py-25oxaz-gly-betahmof 15 9213: phhs-25thiaz-bala-betabenfu9212: 2py-25oxaz-gly-betahmof 15 9213: phhs-25thiaz-bala-betabenfu
9214: bhs-25oxaz-ala-betadmph9214: bhs-25oxaz-ala-betadmph
9215: ibhs-24thiaz-gly-betabenfu9215: ibhs-24thiaz-gly-betabenfu
9216: phhs-oxadiaz-gly-betatbuph9216: phhs-oxadiaz-gly-betatbuph
9217: 2py-me25oxaz-bala-betapy 20 9218: tolhs-nme35pyr-gly-betadito9217: 2py-me25oxaz-bala-betapy 20 9218: tolhs-nme35pyr-gly-betadito
9219: bhs-25thiaz-nmgly-betathio39219: bhs-25thiaz-nmgly-betathio3
9220: bhs-nme35pyr-nmgly-betahph 9221: bhs-25oxaz-ala-betathio3 9222: phhs-24thiaz-gly-betambiph 9223: bhs-24thiaz-bala-betaamibe9220: bhs-nme35pyr-nmgly-betahph 9221: bhs-25oxaz-ala-betathio3 9222: phhs-24thiaz-gly-betambiph 9223: bhs-24thiaz-bala-betaamibe
25 9224 : bhs-24thioph-bala-betabnaphth 9225: tolhs-oxadiaz-gly-zdapch 9226: ibhs-24thiaz-gly-betaftrif 9227: phhs-ithiadiaz-gly-betadmph 9228 : ibhs-25thiaz-bala-betacthioph25 9224: bhs-24thioph-bala-betabnaphth 9225: tolhs-oxadiaz-gly-zdapch 9226: ibhs-24thiaz-gly-betaftrif 9227: phhs-ithiadiaz-gly-betadmph 9228: ibhs-25thiaz-bala-betacthioph
30 9229: bhs-53pyrazo-gly-betapy30 9229: bhs-53pyrazo-gly-betapy
9230: phhs-25thiaz-gly-betaoxaz9230: phhs-25thiaz-gly-betaoxaz
9231: ibhs-nme35pyr-bala-psdap9231: ibhs-nme35pyr-bala-psdap
9232 : bhs-nme35pyr-bala-betal3bendi9232: bhs-nme35pyr-bala-betal3bendi
9233 : ibhs-25oxaz-bala-betabthioph 35 9234: bhs-25oxaz-bala-betadcphee9233: ibhs-25oxaz-bala-betabthioph 35 9234: bhs-25oxaz-bala-betadcphee
9235: tolhs-25methiaz-bala-betamesu 9236: tolhs-25methiaz-gly-betabmph 9237: bhs-24oxaz-gly-betainyl 9238: pahs-25methiaz-bala-betameph 9239: bhs-25methiaz-ala-betacph9235: tolhs-25methiaz-bala-betamesu 9236: tolhs-25methiaz-gly-betabmph 9237: bhs-24oxaz-gly-betainyl 9238: pahs-25methiaz-bala-betameph 9239: bhs-25methiaz-ala-betacph
40 9240 : ibhs-25thiaz-gly-betathiobe 9241: bhs-42nmeim-gly-betadcph 9242: tolhs-oxadiaz-gly-betahni 9243: ibhs-24thiaz-bala-betatos 9244 : dimethpym-24thiaz-gly-betameph40 9240: ibhs-25thiaz-gly-betathiobe 9241: bhs-42nmeim-gly-betadcph 9242: tolhs-oxadiaz-gly-betahni 9243: ibhs-24thiaz-bala-betatos 9244: dimethpym-24thiaz-gly-betameph
45 9245: tolhs-25thiaz-gly-betapyee 9246: hs-24thiaz-gly-betapy 9247 : phhs-24thiaz-gly-betacthioph 9248: bim-35thioph-bala-psdap45 9245: tolhs-25thiaz-gly-betapyee 9246: hs-24thiaz-gly-betapy 9247: phhs-24thiaz-gly-betacthioph 9248: bim-35thioph-bala-psdap
9249 : tolhs-25methiaz-gly-betaamibe9249: tolhs-25methiaz-gly-betaamibe
9250: bim-25oxaz-gly-betadcph9250: bim-25oxaz-gly-betadcph
9251: 2py-46pym-gly-betapy 5 9252: bhs-oxadiaz-ala-betaipro9251: 2py-46pym-gly-betapy 5 9252: bhs-oxadiaz-ala-betaipro
9253: dhim-52thiaz-gly-betameph9253: dhim-52thiaz-gly-betameph
9254: 2py-ithiadiaz-gly-betadcph9254: 2py-ithiadiaz-gly-betadcph
9255: bhs-25methiaz-nmgly-betahmph9255: bhs-25methiaz-nmgly-betahmph
9256: bim-24thioph-gly-betadmph9256: bim-24thioph-gly-betadmph
9257: bhs-25thiaz-bala-aspbzla9257: bras-25thiaz-bala-aspbzla
10 9258: ibhs-25thiaz-bala-betafphe10 9258: ibhs-25thiaz-bala-betafphe
9259 : ibhs-25methiaz-gly-betaanaphth9259: ibhs-25methiaz-gly-betaanaphth
9260 : tolhs-24thioph-bala-betahcbph9260: tolhs-24thioph-bala-betahcbph
9261: phhs-25oxaz-bala-psdaptb9261: phhs-25oxaz-bala-psdaptb
9262 : ibhs-24thioph-gly-betahdbph 15 9263: ibhs-25oxaz-bala-betainyl9262: ibhs-24thioph-gly-betahdbph 15 9263: ibhs-25oxaz-bala-betainyl
9264: tolhs-25oxaz-gly-betahni9264: tolhs-25oxaz-gly-betahni
9265 : bhs-oxadiaz-bala-betamethioph9265: bhs-oxadiaz-bala-betamethioph
9266: 2py-me24oxaz-ala-psdap9266: 2py-me24oxaz-ala-psdap
9267 : tolhs-me24oxaz-ala-beta34meoph 20 9268: bhs-25thiaz-bala-betapyr9267: tolhs-me24oxaz-ala-beta34meoph 20 9268: bhs-25thiaz-bala-betapyr
9269: tolhs-me24oxaz-leu-psdap9269: tolhs-me24oxaz-leu-psdap
9270 : tolhs-24thioph-gly-betapytb9270: tolhs-24thioph-gly-betapytb
9271: bhs-oxadiaz-bala-betapych9271: bras-oxadiaz-bala-betapych
9272 : ibhs-25methiaz-bala-betaphethio9272: ibhs-25methiaz-bala-betaphethio
9273: 2py-thiadiaz-ala-psdap9273: 2py-thiadiaz-ala-psdap
25 9274 : bhs-oxadiaz-nmgly-betal3bendi25 9274: bhs-oxadiaz-nmgly-betal3bendi
9275: tolhs-nme35pyr-gly-betainyl9275: tolhs-nme35pyr-gly-betainyl
9276 : ibhs-25thiaz-bala-betabthioph9276: ibhs-25thiaz-bala-betabthioph
9277: bim-triaz-gly-zdap9277: bim-triaz-gly-zdap
9278: tolhs-24thioph-gly-betacthioph 30 9279: ibhs-nme35pyr-gly-betadhbfu9278: tolhs-24thioph-gly-betacthioph 30 9279: ibhs-nme35pyr-gly-betadhbfu
9280: bhs-25thiaz-bala-betahmofu9280: bras-25thiaz-bala-betahmofu
9281 : ibhs-25oxaz-gly-betaomebendi9281: ibhs-25oxaz-gly-betaomebendi
9282: tolhs-me25thioph-gly-zdap9282: tolhs-me25thioph-gly-zdap
9283: phhs-ithiadiaz-bala-betaheph 35 9284: ibhs-25thiaz-bala-zdapee9283: phhs-ithiadiaz-bala-betaheph 35 9284: ibhs-25thiaz-bala-zdapee
9285 : tolhs-nme35pyr-bala-betabph9285: tolhs-nme35pyr-bala-betabph
9286 : phhs-me24oxaz-bala-betapy9286: phhs-me24oxaz-bala-betapy
9287: 2py-me25thioph-gly-psdap9287: 2py-me25thioph-gly-psdap
9288 : bim-24thiaz-gly-betaomebendi9288: bim-24thiaz-gly-betaomebendi
9289: 2py-42pym-gly-betadcph9289: 2py-42pym-gly-betadcph
40 9290: bim-24im-bala-betadcph40 9290: bim-24im-bala-betadcph
9291: ibhs-25methiaz-gly-betafu29291: ibhs-25methiaz-gly-betafu2
9292: bhs-24thioph-ala-ibsdap9292: bhs-24thioph-ala-ibsdap
9293 : phhs-ithiadiaz-gly-betapbiph9293: phhs-ithiadiaz-gly-betapbiph
9294 : 2pmhs-25thiaz-gly-betathiome 45 9295: phhs-25thiaz-bala-betaoxope9294: 2 pmhs-25thiaz-gly-betathiome 45 9295: phhs-25thiaz-bala-betaoxope
9296 : phhs-me25oxaz-gly-beta34meoph9296: phhs-me25oxaz-gly-beta34meoph
9297 : tolhs-25methiaz-bala-betahni 9298: ibhs-nme35pyr-gly-betaomebendi9297: tolhs-25methiaz-bala-betahni 9298: ibhs-nme35pyr-gly-betaomebendi
9299: bim-42pym-gly-psdap9299: bim-42pym-gly-psdap
9300: tolhs-oxadiaz-gly-betaet9300: tolhs-oxadiaz-gly-betet
9301: tolhs-nme35pyr-gly-betafph 5 9302: bim-25thiaz-leu-zdap9301: tolhs-nme35pyr-gly-betafph 5 9302: bim-25thiaz-leu-zdap
9303: bhs-ithiadiaz-bala-betampy9303: bras-ithiadiaz-bala-betampy
9304: phhs-25methiaz-bala-betatrif9304: phhs-25methiaz-bala-betatrif
9305: phhs-25thiaz-gly-betaph9305: phhs-25thiaz-gly-betaph
9306: sabhs-25thioph-gly-betapy9306: sabhs-25thioph-gly-betapy
9307: phhs-25oxaz-gly-betahmofu9307: phhs-25oxaz-gly-betahmofu
10 9308: imhs-42nmeim-gly-betameph10 9308: imhs-42nmeim-gly-betameph
9309 : bhs-ithiadiaz-bala-betahdcph9309: bhs-ithiadiaz-bala-betahdcph
9310: 2py-35thioph-ala-psdap9310: 2py-35thioph-ala-psdap
9311: bim-42nmeim-gly-betamethi9311: bim-42nmeim-gly-betamethi
9312: bhs-25oxaz-ala-beta23meoph 15 9313: tolhs-25thiaz-gly-betadcphch9312: bhs-25oxaz-ala-beta23meoph 15 9313: tolhs-25thiaz-gly-betadcphch
9314 : phhs-oxadiaz-gly-betabpy9314: phhs-oxadiaz-gly-betabpy
9315: bhs-24oxaz-gly-betadcph9315: bhs-24oxaz-gly-betadcph
9316: bhs-25methiaz-ala-betaipro9316: bhs-25methiaz-ala-betaipro
9317: tolhs-24thiaz-gly-psdapch 20 9318: bim-me24thiaz-bala-betadcph9317: tolhs-24thiaz-gly-psdapch 20 9318: bim-me24thiaz-bala-betadcph
9319: tolhs-nme35pyr-bala-psdap9319: tolhs-nme35pyr-bala-psdap
9320: phhs-25thiaz-bala-betafbph9320: phhs-25thiaz-bala-betafbph
9321: bim-25fur-ala-betapy9321: bim-25fur-ala-betapy
9322 : ibhs-ithiadiaz-gly-betathiome9322: ibhs-ithiadiaz-gly-betathiome
9323: bhs-oxadiaz-bala-betabediox9323: bras-oxadiaz-bala-betabediox
25 9324: dhim-25thiaz-ala-betainyl25 9324: dhim-25thiaz-ala-betainyl
9325: bim-25thiaz-gly-asppha9325: bim-25thiaz-gly-asppha
9326: bhs-nme35pyr-bala-betahmofu9326: bhs-nme35pyr-bala-betahmofu
9327 : bhs-ithiadiaz-bala-betathioph9327: bhs-ithiadiaz-bala-betathioph
9328: bhs-nme35pyr-bala-betacbph 30 9329: bhs-25methiaz-bala-aspbzla9328: bhs-nme35pyr-bala-betacbph 30 9329: bhs-25methiaz-bala-aspbzla
9330 : 2py-me25thioph-gly-betadcph9330: 2py-me25thioph-gly-betadcph
9331 : tolhs-ithiadiaz-bala-betatrif9331: tolhs-ithiadiaz-bala-betatrif
9332: 2pmhs-25thiaz-bala-beta4bph9332: 2 pmhs-25thiaz-bala-beta4bph
9333: ibhs-nme35pyr-gly-betameph 35 9334: tolhs-25thiaz-bala-betatrif9333: ibhs-nme35pyr-gly-betameph 35 9334: tolhs-25thiaz-bala-betatrif
9335: bim-me25thioph-ala-betaph9335: bim-me25thioph-ala-betaph
9336: tolhs-24thiaz-gly-beta3quin9336: tolhs-24thiaz-gly-beta3quin
9337: bhs-26py-ala-betameph9337: bhs-26py-ala-betameph
9338: bhs-42oxaz-bala-psdap9338: bras-42oxaz-bala-psdap
9339: 2py-triaz-bala-betadcph9339: 2py-triaz-bala-betadcph
40 9340: bhs-25methiaz-ala-betabpy40 9340: bhs-25methiaz-ala-betabpy
9341: tolhs-24thioph-bala-zdap9341: tolhs-24thioph-bala-zdap
9342: bhs-me25oxaz-leu-psdap9342: bhs-me25oxaz-leu-psdap
9343 : phhs-25methiaz-bala-betabdimo9343: phhs-25methiaz-bala-betabdimo
9344: bhs-nme35pyr-bala-suabu 45 9345: phhs-25thiaz-bala-betahc9344: bhs-nme35pyr-bala-suabu 45 9345: phhs-25thiaz-bala-betahc
9346: phhs-24thiaz-gly-betaanaphth9346: phhs-24thiaz-gly-betaanaphth
9347: 2py-52thiaz-gly-betameph 9348 : bhs-nme35pyr-gly-asppha9347: 2py-52thiaz-gly-betameph 9348: bhs-nme35pyr-gly-asppha
9349 : dimethpym-42nmeim-gly-betadcph9349: dimethpym-42nmeim-gly-betadcph
9350 : bhs-ithiadiaz-bala-betapbiph9350: bhs-ithiadiaz-bala-betapbiph
9351: bhs-oxadiaz-gly-betaph 5 9352: ibhs-ithiadiaz-gly-betafu29351: bhs-oxadiaz-gly-betaph 5 9352: ibhs-ithiadiaz-gly-betafu2
9353: phhs-25oxaz-bala-betahbcph9353: phhs-25oxaz-bala-betahbcph
9354: bhs-24thiaz-met-betapy9354: bhs-24thiaz-met-betapy
9355 : bhs-ithiadiaz-bala-betatbuph9355: bhs-ithiadiaz-bala-betatbuph
9356: bhs-ithiadiaz-ala-betathioph9356: bhs-ithiadiaz-ala-betathioph
9357 : 2py-25oxaz-gly-beta34meoph9357: 2py-25oxaz-gly-beta34meoph
10 9358: 2py-25thiaz-ala-betadcph10 9358: 2py-25thiaz-ala-betadcph
9359: 2py-me25thioph-gly-betapy9359: 2py-me25thioph-gly-betapy
9360: phhs-ithiadiaz-bala-beta3quin9360: phhs-ithiadiaz-bala-beta3quin
9361: phhs-nme35pyr-gly-betaomebendi9361: phhs-nme35pyr-gly-betaomebendi
9362: bhs-oxadiaz-bala-psdapch 15 9363: ibhs-25oxaz-gly-betaipr9362: bhs-oxadiaz-bala-psdapch 15 9363: ibhs-25oxaz-gly-betaipr
9364 : ibhs-24thiaz-gly-betacthioph9364: ibhs-24thiaz-gly-betacthioph
9365 : phhs-me25thiaz-ala-betaph9365: phhs-me25thiaz-ala-betaph
9366: bhs-24oxaz-leu-zdap9366: bras-24oxaz-leu-zdap
9367: phhs-nme35pyr-gly-betah35dc 20 9368: phhs-me25thioph-ala-beta34meoph9367: phhs-nme35pyr-gly-betah35dc 20 9368: phhs-me25thioph-ala-beta34meoph
9369: dhpyrr-25thiaz-gly-zdap9369: dhpyrr-25thiaz-gly-zdap
9370 : phhs-25thiaz-bala-betaomebendi9370: phhs-25thiaz-bala-betaomebendi
9371: bhs-52thiaz-gly-betadcph9371: bhs-52thiaz-gly-betadcph
9372: phhs-ithiadiaz-gly-betadbph9372: phhs-ithiadiaz-gly-betadbph
9373: 2py-25fur-ala-betadcph9373: 2py-25fur-ala-betadcph
25 9374: gua-24thiazme-gly-betapy25 9374: gua-24thiazme-gly-betapy
9375: tolhs-24thiaz-gly-beta35dbph9375: tolhs-24thiaz-gly-beta35dbph
9376: tolhs-25oxaz-gly-betadbph9376: tolhs-25oxaz-gly-betadbph
9377: phhs-nme35pyr-gly-zdap9377: phhs-nme35pyr-gly-zdap
9378: bhs-me24oxaz-gly-betaph 30 9379: gua-25thiaz-gly-betaimid9378: bhs-me24oxaz-gly-betaph 30 9379: gua-25thiaz-gly-betaimid
9380: tolhs-25oxaz-bala-betaomebendi9380: tolhs-25oxaz-bala-betaomebendi
9381: tolhs-24thiaz-gly-betaipro9381: tolhs-24thiaz-gly-betaipro
9382: bim-triaz-ala-betapy9382: bim-triaz-ala-betapy
9383: bhs-24thioph-gly-zdapee 35 9384: ibhs-nme35pyr-gly-betafluo9383: bhs-24thioph-gly-zdapee 35 9384: ibhs-nme35pyr-gly-betafluo
9385 : ibhs-25oxaz-bala-betaomebendi9385: ibhs-25oxaz-bala-betaomebendi
9386 : phhs-25methiaz-bala-betapytb9386: phhs-25methiaz-bala-betapytb
9387 : bhs-25methiaz-bala-betapyr9387: bras-25methiaz-bala-betapyr
9388: tolhs-25oxaz-bala-betacph9388: tolhs-25oxaz-bala-betacph
9389 : phhs-oxadiaz-bala-aspbzla9389: phhs-oxadiaz-bala-aspbzla
40 9390 : tolhs-25methiaz-bala-betaftrif40 9390: tolhs-25methiaz-bala-betaftrif
9391 : tolhs-ithiadiaz-bala-betabthioph9391: tolhs-ithiadiaz-bala-betabthioph
9392: bhs-24thiaz-gly-betamesu9392: bhs-24thiaz-gly-betamesu
9393: bhs-24thiaz-ala-betadhbfu9393: bhs-24thiaz-ala-betadhbfu
9394 : tolhs-24thioph-bala-betadcphch 45 9395: ibhs-nme35pyr-bala-zdapch9394: tolhs-24thioph-bala-betadcphch 45 9395: ibhs-nme35pyr-bala-zdapch
9396: bhs-oxadiaz-gly-betahph9396: bras-oxadiaz-gly-betahph
9397 : bhs-25oxaz-gly-betaol 9398: tolhs-24thioph-gly-zdap9397: bhs-25oxaz-gly-betaol 9398: tolhs-24thioph-gly-zdap
9399: bhs-oxadiaz-ala-betadmoph9399: bhs-oxadiaz-ala-betadmoph
9400: phhs-oxadiaz-bala-betapyr9400: phhs-oxadiaz-bala-betapyr
9401: bhs-nme35pyr-bala-aspbzla 5 9402: 2py-25oxaz-bala-betamethi9401: bhs-nme35pyr-bala-aspbzla 5 9402: 2py-25oxaz-bala-betamethi
9403: bhs-oxadiaz-gly-betahcbph9403: bras-oxadiaz-gly-betahcbph
9404: tolhs-ithiadiaz-bala-aspaba9404: tolhs-ithiadiaz-bala-aspaba
9405: ibhs-oxadiaz-bala-betambiph9405: ibhs-oxadiaz-bala-betambiph
9406: bim-thiadiaz-ala-zdap9406: bim-thiadiaz-ala-zdap
9407 : phhs-24thioph-bala-betatbuph9407: phhs-24thioph-bala-betatbuph
10 9408: bhs-25thiaz-gly-betaipr10 9408: bhs-25thiaz-gly-betaipr
9409: tolhs-25methiaz-bala-betacthioph9409: tolhs-25methiaz-bala-betacthioph
9410: phhs-24thiaz-bala-betadmoph9410: phhs-24thiaz-bala-betadmoph
9411: gua-42pym-gly-betal3bendi9411: gua-42pym-gly-betal3bendi
9412: tolhs-25methiaz-gly-betahmph 15 9413: ibhs-25oxaz-gly-betameph9412: tolhs-25methiaz-gly-betahmph 15 9413: ibhs-25oxaz-gly-betameph
9414: bhs-24thiaz-bala-psdaptb9414: bhs-24thiaz-bala-psdaptb
9415 : bhs-nme35pyr-gly-betadcphtb9415: bhs-nme35pyr-gly-betadcphtb
9416: bhs-24thiaz-bala-betadmph9416: bhs-24thiaz-bala-betadmph
9417: phhs-ithiadiaz-gly-busu2be 20 9418: bim-24thiaz-ala-betainyl9417: phhs-ithiadiaz-gly-busu2be 20 9418: bim-24thiaz-ala-betainyl
9419: phhs-25oxaz-bala-betahmph9419: phhs-25oxaz-bala-betahmph
9420: phhs-25thiaz-gly-psdapee9420: phhs-25thiaz-gly-psdapee
9421: ibhs-nme35pyr-bala-betahmph9421: ibhs-nme35pyr-bala-betahmph
9422: gua-24oxaz-gly-betaphethioa9422: gua-24oxaz-gly-betaphethioa
9423 : 2pmhs-42nmeim-gly-betadmoph9423: 2 pmhs-42nmeim-gly-betadmoph
25 9424: ibhs-24thioph-bala-betadbph25 9424: ibhs-24thioph-bala-betadbph
9425: phhs-ithiadiaz-bala-betabmph9425: phhs-ithiadiaz-bala-betabmph
9426: bim-24oxaz-ala-betapy9426: bim-24oxaz-ala-betapy
9427 : tolhs-25methiaz-gly-betafbph9427: tolhs-25methiaz-gly-betafbph
9428: bhs-25oxaz-gly-betapy 30 9429: bhs-nme35pyr-bala-betafph9428: bhs-25oxaz-gly-betapy 30 9429: bhs-nme35pyr-bala-betafph
9430: 2py-24thiaz-bala-betahni9430: 2py-24thiaz-bala-betahni
9431 : phhs-ithiadiaz-bala-betafu29431: phhs-ithiadiaz-bala-betafu2
9432: impy-42nmeim-phe-betadcph9432: impy-42nmeim-phe-betadcph
9433: tolhs-24thioph-gly-betadcph 35 9434: bhs-ithiadiaz-gly-betafbph9433: tolhs-24thioph-gly-betadcph 35 9434: bhs-ithiadiaz-gly-betafbph
9435: bhs-nme35pyr-gly-betameph9435: bhs-nme35pyr-gly-betameph
9436: bhs-25oxaz-gly-betabpy9436: bhs-25oxaz-gly-betabpy
9437: ibhs-25oxaz-gly-psdapee9437: ibhs-25oxaz-gly-psdapee
9438: bim-25fur-bala-betadcph9438: bim-25fur-bala-betadcph
9439: bhs-25thiaz-gly-aspbzla9439: bhs-25thiaz-gly-aspbzla
40 9440: 2py-oxadiaz-ala-psdap40 9440: 2py-oxadiaz-ala-psdap
9441: bim-24thiaz-leu-zdap9441: bim-24thiaz-leu-zdap
9442 : tolhs-oxadiaz-gly-betampy9442: tolhs-oxadiaz-gly-betampy
9443: 2pmhs-25thioph-ala-betameph9443: 2 pmhs-25thioph-ala-betameph
9444: bhs-25thioph-ala-zdap 45 9445: bhs-24thioph-gly-betaomebendi9444: bhs-25thioph-ala-zdap 45 9445: bhs-24thioph-gly-betaomebendi
9446 : phhs-25oxaz-gly-betaibph9446: phhs-25oxaz-gly-betaibph
9447: bhs-42nmeim-leu-zdap 9448: bhs-oxadiaz-leu-betadcph 9449: bhs-ithiadiaz-ala-betahmph 9450 : bhs-25methiaz-gly-betadcphch 9451: tolhs-nme35pyr-gly-betaphethioa 9452: gua-26py-gly-betatos 9453: bhs-24thiaz-bala-betadtrif 9454 : ibhs-ithiadiaz-bala-betaibph 9455: dhim-26py-ala-betaph 9456: bim-35thioph-ala-psdap 9457: phhs-25thiaz-bala-betaamibe9447: bhs-42nmeim-leu-zdap 9448: bhs-oxadiaz-leu-betadcph 9449: bhs-ithiadiaz-ala-betahmph 9450: bhs-25methiaz-gly-betadcphch 9451: tolhs-nme35pyr-gly-betaphethioa 9452: gua-26py-gly-bethos 9243: -bala-betadtrif 9454: ibhs-ithiadiaz-bala-betaibph 9455: dhim-26py-ala-betaph 9456: bim-35thioph-ala-psdap 9457: phhs-25thiaz-bala-betaamibe
10 9458: 2py-26py-ala-psdap 9459: 2py-25thiaz-gly-beta3quin 9460: bhs-25methiaz-bala-betapym 9461 : tolhs-24thiaz-bala-betapbiph 9462 : tolhs-ithiadiaz-gly-betamesu10 9458: 2py-26py-ala-psdap 9459: 2py-25thiaz-gly-beta3quin 9460: bhs-25methiaz-bala-betapym 9461: tolhs-24thiaz-bala-betapbiph 9462: tolhs-ithiadiaz-gly-betamesu
15 9463: phhs-24thioph-bala-betathiome 9464 : ibhs-25oxaz-gly-betaphethio 9465: tolhs-oxadiaz-gly-betadmph 9466: ibhs-24thiaz-bala-betadbph 9467: bim-nme35pyr-bala-aspaba15 9463: phhs-24thioph-bala-betathiome 9464: ibhs-25oxaz-gly-betaphethio 9465: tolhs-oxadiaz-gly-betadmph 9466: ibhs-24thiaz-bala-betadbph 9467: bim-nme35pyr-bala-aspaba
20 9468: 2py-35fur-ala-zdap20 9468: 2py-35fur-ala-zdap
9469 : phhs-ithiadiaz-bala-betahcbph 9470 : ibhs-25methiaz-gly-betapbiph 9471 : tolhs-25methiaz-bala-betadcphch 9472 : ibhs-25methiaz-gly-betatbuph 9473 : bim-42oxaz-bala-betapy9469: phhs-ithiadiaz-bala-betahcbph 9470: ibhs-25methiaz-gly-betapbiph 9471: tolhs-25methiaz-bala-betadcphch 9472: ibhs-25methiaz-gly-betatbuph 9473: bim-42oxaz-bala-betapy
25 9474: phhs-24thiaz-gly-zdapch 9475: tolhs-24thiaz-bala-betatos 9476: bhs-42oxaz-bala-betapy 9477: bim-35fur-bala-betadcph 9478: 2py-me24thioph-ala-betapy25 9474: phhs-24thiaz-gly-zdapch 9475: tolhs-24thiaz-bala-betatos 9476: bhs-42oxaz-bala-betapy 9477: bim-35fur-bala-betadcph 9478: 2py-me24thioph-ala-betapy
30 9479: tolhs-25oxaz-gly-betamesu30 9479: tolhs-25oxaz-gly-betamesu
9480 : tolhs-nme35pyr-gly-betabnaphth 9481: ibhs-oxadiaz-gly-betahdcph 9482 : tolhs-24thiaz-bala-aspbzla 9483: phhs-oxadiaz-bala-zdapch9480: tolhs-nme35pyr-gly-betabnaphth 9481: ibhs-oxadiaz-gly-betahdcph 9482: tolhs-24thiaz-bala-aspbzla 9483: phhs-oxadiaz-bala-zdapch
35 9484: ibhs-ithiadiaz-gly-psdapee 9485: ibhs-nme35pyr-gly-beta35dbph 9486 : ibhs-24thiaz-gly-betabnaphth 9487: bhs-ithiadiaz-gly-betafph 9488: bhs-42nmeim-gly-betafluo 9489: phhs-25thiaz-bala-betatrif35 9484: ibhs-ithiadiaz-gly-psdapee 9485: ibhs-nme35pyr-gly-beta35dbph 9486: ibhs-24thiaz-gly-betabnaphth 9487: bhs-ithiadiaz-gly-betafph 9488: bhs-42nmeim-gly-bet9 phafho 25thiaz-bala-betatrif
40 9490: tolhs-nme35pyr-bala-betaph 9491 : ibhs-25methiaz-bala-beta34dcph 9492: bim-24oxaz-gly-zdap 9493: bhs-25thiaz-bala-beta4bph 9494: bhs-25thioph-gly-betapy40 9490: tolhs-nme35pyr-bala-betaph 9491: ibhs-25methiaz-bala-beta34dcph 9492: bim-24oxaz-gly-zdap 9493: bhs-25thiaz-bala-beta4bph 9494: bhs-25thioph-gly-betapy
45 9495: bhs-25methiaz-bala-psdapch 9496: bhs-25oxaz-nmgly-betadmph 9497: phhs-me25thioph-ala-betapy 9498: ibhs-oxadiaz-bala-betafu345 9495: bhs-25methiaz-bala-psdapch 9496: bhs-25oxaz-nmgly-betadmph 9497: phhs-me25thioph-ala-betapy 9498: ibhs-oxadiaz-bala-betafu3
9499: ibhs-24thiaz-bala-betamethi9499: ibhs-24thiaz-bala-betamethi
9500 : phhs-24thioph-bala-betatrif9500: phhs-24thioph-bala-betatrif
9501: tolhs-25oxaz-gly-betathio3 5 9502: bim-25thioph-gly-psdap9501: tolhs-25oxaz-gly-betathio3 5 9502: bim-25thioph-gly-psdap
9503 : phhs-ithiadiaz-bala-betahdbph9503: phhs-ithiadiaz-bala-betahdbph
9504 : tolhs-25oxaz-gly-betaomebendi9504: tolhs-25oxaz-gly-betaomebendi
9505: phhs-me24thioph-ala-psdap9505: phhs-me24thioph-ala-psdap
9506: ibhs-ithiadiaz-gly-betafph9506: ibhs-ithiadiaz-gly-betafph
9507: phhs-oxadiaz-bala-betaol9507: phhs-oxadiaz-bala-betaol
1010
9508: bhs-ithiadiaz-ala-betadhbfu9508: bhs-ithiadiaz-ala-betadhbfu
9509 : ibhs-oxadiaz-gly-betabnaphth9509: ibhs-oxadiaz-gly-betabnaphth
9510: bhs-nme35pyr-ala-betadhbfu9510: bhs-nme35pyr-ala-betadhbfu
9511 : bhs-ithiadiaz-nmgly-betaipro9511: bhs-ithiadiaz-nmgly-betaipro
9512: 2py-oxadiaz-bala-zdap 15 9513: phhs-25oxaz-bala-beta23meoph9512: 2py-oxadiaz-bala-zdap 15 9513: phhs-25oxaz-bala-beta23meoph
9514: bhs-me24oxaz-bala-betapy9514: bhs-me24oxaz-bala-betapy
9515: ibhs-24thiaz-gly-zdap9515: ibhs-24thiaz-gly-zdap
9516: bhs-me25thioph-leu-psdap9516: bhs-me25thioph-leu-psdap
9517: phhs-oxadiaz-bala-betafbph 20 9518: bhs-ithiadiaz-bala-betabmph9517: phhs-oxadiaz-bala-betafbph 20 9518: bhs-ithiadiaz-bala-betabmph
9519 : bhs-25methiaz-gly-betaphethioa9519: bhs-25methiaz-gly-betaphethioa
9520: bhs-24thiaz-bala-suabu9520: bras-24thiaz-bala-suabu
9521 : tolhs-25methiaz-bala-betacbph9521: tolhs-25methiaz-bala-betacbph
9522 : tolhs-25methiaz-gly-betaheph9522: tolhs-25methiaz-gly-betaheph
9523 : phhs-25thiaz-gly-beta34dcph9523: phhs-25thiaz-gly-beta34dcph
2525
9524 : impy-25methiaz-nmgly-psdap9524: impy-25methiaz-nmgly-psdap
9525: bhs-oxadiaz-nmgly-betabpy9525: bhs-oxadiaz-nmgly-betabpy
9526: bhs-25thiaz-bala-zdap9526: bras-25thiaz-bala-zdap
9527: tolhs-24thiaz-gly-busu2be9527: tolhs-24thiaz-gly-busu2be
9528: 2py-24thiaz-leu-psdap 30 9529: bhs-nme35pyr-gly-betadmoph9528: 2py-24thiaz-leu-psdap 30 9529: bhs-nme35pyr-gly-betadmoph
9530: ibhs-25thiaz-bala-betafluo9530: ibhs-25thiaz-bala-betafluo
9531: tolhs-rιme35pyr-gly-betahmph9531: tolhs-rιme35pyr-gly-betahmph
9532: tolhs-oxadiaz-gly-betahb9532: tolhs-oxadiaz-gly-betahb
9533 : bhs-ithiadiaz-gly-betaheph 35 9534: phhs-oxadiaz-bala-betaomebendi9533: bhs-ithiadiaz-gly-betaheph 35 9534: phhs-oxadiaz-bala-betaomebendi
9535: bhs-oxadiaz-gly-zdap9535: bhs-oxadiaz-gly-zdap
9536 : bhs-25methiaz-gly-betahdcph9536: bhs-25methiaz-gly-betahdcph
9537: ibhs-25thiaz-bala-zdap9537: ibhs-25thiaz-bala-zdap
9538: tolhs-25methiaz-bala-betathiome9538: tolhs-25methiaz-bala-betathiome
9539 : phhs-ithiadiaz-bala-betaimid9539: phhs-ithiadiaz-bala-betaimid
40 9540: phhs-24thiaz-gly-betapyee40 9540: phhs-24thiaz-gly-betapyee
9541 : tolhs-ithiadiaz-bala-betaphethioa9541: tolhs-ithiadiaz-bala-betaphethioa
9542: ibhs-24thiaz-bala-zdap9542: ibhs-24thiaz-bala-zdap
9543 : phhs-25thiaz-gly-betaomebendi9543: phhs-25thiaz-gly-betaomebendi
9544: bhs-25oxaz-bala-psdaptb 45 9545: bhs-25oxaz-gly-betaph9544: bhs-25oxaz-bala-psdaptb 45 9545: bhs-25oxaz-gly-betaph
9546 : ibhs-25methiaz-gly-betahc9546: ibhs-25methiaz-gly-betahc
9547: tolhs-25methiaz-bala-betahb 9548 : tolhs-nme35pyr-bala-betadcphch9547: tolhs-25methiaz-bala-betahb 9548: tolhs-nme35pyr-bala-betadcphch
9549: gua-25thioph-gly-betamesu9549: gua-25thioph-gly-betamesu
9550 : tolhs-24thioph-bala-betadcphee9550: tolhs-24thioph-bala-betadcphee
9551: bhs-oxadiaz-ala-betaoxaz 5 9552: ibhs-25oxaz-gly-betathio39551: bhs-oxadiaz-ala-betaoxaz 5 9552: ibhs-25oxaz-gly-betathio3
9553: phhs-24thioph-gly-betafluo9553: phhs-24thioph-gly-betafluo
9554: bim-25oxaz-gly-betameph9554: bim-25oxaz-gly-betameph
9555: bim-25methiaz-gly-aspibua9555: bim-25methiaz-gly-aspibua
9556: bim-me25oxaz-bala-psdap9556: bim-me25oxaz-bala-psdap
9557: ibhs-oxadiaz-gly-zdapch9557: ibhs-oxadiaz-gly-zdapch
10 9558: 2py-oxadiaz-bala-aspaba10 9558: 2py-oxadiaz-bala-aspaba
9559: bhs-oxadiaz-nmgly-betainyl9559: bhs-oxadiaz-nmgly-betainyl
9560 : tolhs-25methiaz-bala-betaipro9560: tolhs-25methiaz-bala-betaipro
9561: bhs-25fur-gly-betapy9561: bhs-25fur-gly-betapy
9562: bhs-25thioph-ala-psdap 15 9563 : ibhs-oxadiaz-gly-betadcphch9562: bhs-25thioph-ala-psdap 15 9563: ibhs-oxadiaz-gly-betadcphch
9564: phhs-25oxaz-bala-betafluo9564: phhs-25oxaz-bala-betafluo
9565: phhs-25oxaz-bala-betadbph9565: phhs-25oxaz-bala-betadbph
9566 : ibhs-oxadiaz-gly-betaomebendi9566: ibhs-oxadiaz-gly-betaomebendi
9567 : ibhs-nme35pyr-gly-betaphethio 2o 9568: bhs-25oxaz-bala-betabpy9567: ibhs-nme35pyr-gly-betaphethio 2o 9568: bhs-25oxaz-bala-betabpy
9569: phhs-25thiaz-bala-betaipro9569: phhs-25thiaz-bala-betaipro
9570: 2py-nme35pyr-ala-betapy9570: 2py-nme35pyr-ala-betapy
9571: ibhs-24thiaz-bala-betahb9571: ibhs-24thiaz-bala-betahb
9572 : bhs-24thioph-gly-betaimid9572: bhs-24thioph-gly-betaimide
9573 : bhs-25methiaz-bala-betaoxope9573: bhs-25methiaz-bala-betaoxope
25 9574: ibhs-ithiadiaz-bala-betahmph25 9574: ibhs-ithiadiaz-bala-betahmph
9575: 2py-24thiaz-leu-zdap9575: 2py-24thiaz-leu-zdap
9576: bhs-25methiaz-gly-betapym9576: bhs-25methiaz-gly-betapym
9577: bhs-ithiadiaz-ala-betaoxaz9577: bhs-ithiadiaz-ala-betaoxaz
9578 : ibhs-24thioph-bala-betaimid 30 9579: ibhs-24thioph-gly-beta23meoph9578: ibhs-24thioph-bala-betaimid 30 9579: ibhs-24thioph-gly-beta23meoph
9580: bim-me24oxaz-gly-zdap9580: bim-me24oxaz-gly-zdap
9581: tolhs-nme35pyr-gly-betahc9581: tolhs-nme35pyr-gly-betahc
9582: bhs-25thiophme-gly-betapy9582: bhs-25thiophme-gly-betapy
9583: bhs-25oxaz-gly-betambiph 35 9584: phhs-25oxaz-bala-betadito9583: bhs-25oxaz-gly-betambiph 35 9584: phhs-25oxaz-bala-betadito
9585 : phhs-25methiaz-gly-betatbuph9585: phhs-25methiaz-gly-betatbuph
9586 : tolhs-24thiaz-bala-betapytb9586: tolhs-24thiaz-bala-betapytb
9587 : impy-25thiaz-bala-betah35dc9587: impy-25thiaz-bala-betah35dc
9588: bhs-nme35pyr-bala-zdaptb9588: bhs-nme35pyr-bala-zdaptb
9589: 2py-26py-ser-zdap9589: 2py-26py-ser-zdap
40 9590: dhim-42pym-gly-betadcph40 9590: dhim-42pym-gly-betadcph
9591 : 2py-me25thioph-bala-betadcph9591: 2py-me25thioph-bala-betadcph
9592 : tolhs-oxadiaz-bala-betathiobe9592: tolhs-oxadiaz-bala-betathiobe
9593: ibhs-24thiaz-bala-betaipr9593: ibhs-24thiaz-bala-betaipr
9594 : phhs-nme35pyr-bala-betahcbph 45 9595: gua-24thiaz-gly-betaipro9594: phhs-nme35pyr-bala-betahcbph 45 9595: gua-24thiaz-gly-betaipro
9596: tolhs-oxadiaz-bala-betatos9596: tolhs-oxadiaz-bala-betatos
9597: phhs-24thiaz-bala-betatrif 9598 : tolhs-ithiadiaz-gly-betadhbfu 9599: 2pmhs-25methiaz-bala-zdap 9600: gua-24oxaz-gly-betabmph 9601: bhs-oxadiaz-bala-zdaptb 9602: bhs-oxadiaz-nmgly-betadhbfu 9603: phhs-25thiaz-gly-betahmo 9604 : phhs-ithiadiaz-gly-betamethioph 9605: bhs-ithiadiaz-leu-zdap 9606: tolhs-24thiaz-gly-betapytb 9607: ibhs-24thioph-gly-betaet9597: phhs-24thiaz-bala-betatrif 9598: tolhs-ithiadiaz-gly-betadhbfu 9599: 2 pmhs-25methiaz-bala-zdap 9600: gua-24oxaz-gly-betabmph 9601: bhs-oxadiaz-bala-zdaptb 9602: bhs-oxadiaz-nmgly-betadhhfu 9603: ph -gly-betahmo 9604: phhs-ithiadiaz-gly-betamethioph 9605: bhs-ithiadiaz-leu-zdap 9606: tolhs-24thiaz-gly-betapytb 9607: ibhs-24thioph-gly-betaet
10 9608: phhs-25thiaz-gly-betainyl 9609: tolhs-oxadiaz-bala-betathio3 9610: bhs-25oxaz-ala-betabnaphth 9611: bim-nme35pyr-gly-zdap 9612: 2py-25thioph-gly-betadcph10 9608: phhs-25thiaz-gly-betainyl 9609: tolhs-oxadiaz-bala-betathio3 9610: bhs-25oxaz-ala-betabnaphth 9611: bim-nme35pyr-gly-zdap 9612: 2py-25thioph-gly-betadcph
15 9613: phhs-24thioph-gly-betadcphee 9614 : ibhs-24thioph-gly-betal3bendi 9615: bhs-42pym-gly-zdap 9616: 2py-24im-bala-betapy 9617: phhs-25methiaz-gly-psdapee15 9613: phhs-24thioph-gly-betadcphee 9614: ibhs-24thioph-gly-betal3bendi 9615: bhs-42pym-gly-zdap 9616: 2py-24im-bala-betapy 9617: phhs-25methiaz-gly-psdapee
20 9618: bhs-24im-leu-betadcph 9619: phhs-24thiaz-bala-betafphe 9620: tolhs-24thiaz-bala-psdap 9621: bhs-nme35pyr-bala-betapy 9622 : impy-42nmeim-gly-betal3bendi 9623: phhs-25thiaz-bala-betadhbfu20 9618: bhs-24im-leu-betadcph 9619: phhs-24thiaz-bala-betafphe 9620: tolhs-24thiaz-bala-psdap 9621: bhs-nme35pyr-bala-betapy 9622: impy-42nmeim-gly-betal3bendi 9623: phhs- 25thiaz-bala-betadhbfu
25 9624: ibhs-24thiaz-bala-betabpy 9625: phhs-oxadiaz-bala-aspibua 9626: ibhs-nme35pyr-gly-betafu2 9627: 2pmhs-42nmeim-bala-ibsdap 9628: bhs-25thiaz-gly-betahc25 9624: ibhs-24thiaz-bala-betabpy 9625: phhs-oxadiaz-bala-aspibua 9626: ibhs-nme35pyr-gly-betafu2 9627: 2 pmhs-42nmeim-bala-ibsdap 9628: bhs-25thiaz-gly-betahc
30 9629: bim-42pym-gly-betainyl 9630: bim-me25thiaz-gly-psdap 9631: phhs-ithiadiaz-bala-betafu3 9632 : bhs-24thioph-nmgly-betathioph 9633: bim-42pym-gly-zdap30 9629: bim-42pym-gly-betainyl 9630: bim-me25thiaz-gly-psdap 9631: phhs-ithiadiaz-bala-betafu3 9632: bhs-24thioph-nmgly-betathioph 9633: bim-42pym-gly-zdap
35 9634: ibhs-24thiaz-gly-betabmph 9635: phhs-24thioph-gly-beta23meoph 9636: phhs-24thiaz-gly-betadito 9637: phhs-25oxaz-gly-beta3quin 9638: bim-nme35pyr-gly-aspibua 9639: bim-oxadiaz-gly-aspibua35 9634: ibhs-24thiaz-gly-betabmph 9635: phhs-24thioph-gly-beta23meoph 9636: phhs-24thiaz-gly-betadito 9637: phhs-25oxaz-gly-beta3quin 9638: bim-nme35pyr-gly-aspibua 9639: bim- oxadiaz-gly-aspibua
40 9640 : tolhs-25thiaz-gly-betahcbph 9641: ibhs-ithiadiaz-gly-asppha 9642: irtrpy-25oxaz-met-psdap 9643: ibhs-nme35pyr-bala-betahc 9644: 2py-25fur-gly-betadcph 45 9645: tolhs-24thioph-bala-betaomebendi 9646: gua-24thiaz-gly-betahmofu 9647: ibhs-25methiaz-bala-zdapch 9648: 2py-24thiaz-bala-zdap40 9640: tolhs-25thiaz-gly-betahcbph 9641: ibhs-ithiadiaz-gly-asppha 9642: irtrpy-25oxaz-met-psdap 9643: ibhs-nme35pyr-bala-betahc 9644: 2py-25fur-gly-betadcph 45 9645: tolhs -24thioph-bala-betaomebendi 9646: gua-24thiaz-gly-betahmofu 9647: ibhs-25methiaz-bala-zdapch 9648: 2py-24thiaz-bala-zdap
9649: bhs-24thiaz-gly-beta4bph9649: bhs-24thiaz-gly-beta4bph
9650: phhs-24thioph-gly-betahdcph9650: phhs-24thioph-gly-betahdcph
9651: bhs-42nmeim-bala-psdap 5 9652: phhs-25thiaz-gly-aspbzla9651: bhs-42nmeim-bala-psdap 5 9652: phhs-25thiaz-gly-aspbzla
9653: 2py-24thioph-ala-betadcph9653: 2py-24thioph-ala-betadcph
9654: bhs-24thiaz-ala-betahmph9654: bhs-24thiaz-ala-betahmph
9655: bhs-triaz-leu-zdap9655: bhs-triaz-leu-zdap
9656 : tolhs-nme35pyr-bala-betaftrif9656: tolhs-nme35pyr-bala-betaftrif
9657 : bhs-ithiadiaz-bala-betal3bendi9657: bhs-ithiadiaz-bala-betal3bendi
10 9658: ibhs-25methiaz-gly-betahmo10 9658: ibhs-25methiaz-gly-betahmo
9659: ibhs-24thioph-gly-betahmofu9659: ibhs-24thioph-gly-betahmofu
9660: bhs-25oxaz-bala-asppha9660: bras-25oxaz-bala-asppha
9661 : tolhs-25methiaz-gly-betaftrif9661: tolhs-25methiaz-gly-betaftrif
9662: bhs-oxadiaz-gly-betacph 15 9663: phhs-25oxaz-gly-betabenfu9662: bhs-oxadiaz-gly-betacph 15 9663: phhs-25oxaz-gly-betabenfu
9664: dhim-24oxaz-ala-betadcph9664: dhim-24oxaz-ala-betadcph
9665: tolhs-25oxaz-bala-aspaba9665: tolhs-25oxaz-bala-aspaba
9666: bhs-25thiaz-bala-psdaptb9666: bhs-25thiaz-bala-psdaptb
9667: bhs-25oxaz-nmala-psdap 20 9668: 4pmhs-24thioph-bala-betameph9667: bhs-25oxaz-nmala-psdap 20 9668: 4 pmhs-24thioph-bala-betameph
9669 : bhs-nme35pyr-bala-betahmo9669: bhs-nme35pyr-bala-betahmo
9670 : ibhs-nme35pyr-gly-betaanaphth9670: ibhs-nme35pyr-gly-betaanaphth
9671: dhim-52thiaz-ala-betapy9671: dhim-52thiaz-ala-betapy
9672 : bim-52thiaz-gly-psdap9672: bim-52thiaz-gly-psdap
2525
00
55
00
5 Die Abkürzungen nach dem Doppelpunkt in der vorstehenden Liste stehen getrennt durch einen Bindungsstrich jeweils für ein Strukturelement A, E, G und L, wobei die Abkürzungen folgende Bedeutung haben:5 The abbreviations after the colon in the list above stand for a structural element A, E, G and L, separated by a hyphen. The abbreviations have the following meaning:
In der Tabelle bedeutet Et : Ethyl und iPr : iso-Propyl .In the table, Et means ethyl and iPr means isopropyl.
Verbindungen der allgemeinen Formel I und die zu ihrer Her- Stellung verwendeten Ausgangsstoffe lassen sich generell nach dem Fachmann bekannten Methoden der organischen Chemie herstellen, wie es in Standardwerken wie beispielsweise Houben-Weyl , "Methoden der Organischen Chemie", Thieme-Verlag, Stuttgart, oder March "Advanced Organic Chemistry" , 4th Edition, Wiley & Sons, beschrieben ist.Compounds of the general formula I and the starting materials used for their preparation can generally be prepared by methods of organic chemistry known to the person skilled in the art, as described in standard works such as, for example, Houben-Weyl, "Methods of Organic Chemistry", Thieme-Verlag, Stuttgart, or March "Advanced Organic Chemistry", 4th Edition, Wiley & Sons.
Die Synthese von Verbindungen der Formel I kann entweder nach "klassischer" Methode in Lösung durch Fragmentkondensation einzelner Bausteine in Lösung oder an einem polymeren Träger durchgeführt werden, wobei jeweils Reaktionsbedingungen verwendet werden, wie sie für die jeweiligen Umsetzungen bekannt und ge- eignet sind. Dabei kann auch von an sich bekannten, hier nicht erwähnten Varianten Gebrauch gemacht werden.The synthesis of compounds of the formula I can be carried out either according to the "classic" method in solution by fragment condensation of individual building blocks in solution or on a polymeric support, reaction conditions being used in each case as are known and suitable for the respective reactions. Use can also be made of variants which are known per se and are not mentioned here.
Die Kupplung der einzelnen Fragmente und die Abspaltung der Schutzgruppen kann nach bekannten Verfahren analog den Methoden der Peptidsynthese erfolgen, wie in Standardwerken z.B. in Bodanszky "The Practice of Peptide Synthesis", 2nd Edition, Springer-Verlag 1994, und Bodanszky "Principles of Peptide Synthesis", Springer-Verlag 1984, beschrieben ist. Methoden zur Festphasensynthese und Anwendungen sind z.B. beschrieben in J. Am. Chem. Soc. 1972, 94, 3102ff, Int. J. Peptide Protein Res. 1990, 35, 161-214; Angew. Chem. 1992, 375-391, J. Med. Chem. 1994, 37, 1233, J. Med. Chem. 1994, 37, 1385, und Angew. Chem. 1996, 108, 2437-2488. Eine allgemeine Übersicht der gängigen Methoden zur Peptidsynthese und eine Auflistung geeigneter Reagenzien ist weiterhin zu finden in NOVABIOCHEM 1999 "Catalog and Peptide Synthesis Handbook" .The coupling of the individual fragments and the splitting off of the protective groups can be carried out by known methods analogously to the methods of peptide synthesis, as in standard works e.g. in Bodanszky "The Practice of Peptide Synthesis", 2nd Edition, Springer-Verlag 1994, and Bodanszky "Principles of Peptide Synthesis", Springer-Verlag 1984. Methods for solid phase synthesis and applications are e.g. described in J. Am. Chem. Soc. 1972, 94, 3102ff, Int. J. Peptide Protein Res. 1990, 35, 161-214; Appl. Chem. 1992, 375-391, J. Med. Chem. 1994, 37, 1233, J. Med. Chem. 1994, 37, 1385, and Angew. Chem. 1996, 108, 2437-2488. A general overview of the common methods for peptide synthesis and a list of suitable reagents can also be found in NOVABIOCHEM 1999 "Catalog and Peptide Synthesis Handbook".
Die allgemeine Synthese von Verbindungen der Formel I ist in den Schemata 1-8 beschrieben. Sofern nicht anders angegeben sind sämtliche Ausgangsmaterialien und Reagenzien käuflich, oder lassen sich aus käuflich erhältlichen Vorprodukten nach gängigen Methoden herstellen.The general synthesis of compounds of formula I is described in Schemes 1-8. Unless otherwise stated, all starting materials and reagents are commercially available, or they can be prepared from commercially available intermediate products using standard methods.
Schema 1-3 beschreibt allgemein den Aufbau von Verbindungen der Formel I. Die Synthese kann prinzipiell durch N-terminale Verlängerung von Baustein II erfolgen (Schema 1). Kupplung von II mit III ergibt IV, Abspaltung der Schutzgruppe SG3 zu V und erneute Kupplung mit VI führt zu VII.Scheme 1-3 generally describes the structure of compounds of formula I. The synthesis can in principle be carried out by N-terminal extension of building block II (Scheme 1). Coupling from II with III results in IV, splitting off the protective group SG3 to V and renewed coupling with VI leads to VII.
Alternativ können Verbindungen des Typs I auch durch C-terminale Verlängerung ausgehend von Baustein VI hergestellt werden. Kupplung mit VIII ergibt IX, Abspaltung der Schutzgruppe SG2 und erneute Kupplung mit II führt zu VII (Schema 2).Alternatively, type I compounds can also be prepared by C-terminal extension starting from building block VI. Coupling with VIII gives IX, splitting off of protective group SG2 and renewed coupling with II leads to VII (Scheme 2).
Verbindungen der allgemeinen Formel I erhält man letztendlich nach Abspaltung der Schutzgruppe SGI in VII (Schema 3). Zur Ermöglichung einer detaillierteren Beschreibung werden in den Syntheseschemata statt der Gruppe T bereits Carbonsäurederivat- reste, wie beispielsweise die Gruppe -CO-R1, eine bevorzugten Ausführungsform der Gruppe Z gezeigt. Die Synthese mit der entsprechenden Gruppe Z läuft analog. Für den Fall, daß in den Resten R2, R3, R4, R5, R6, Q oder A funktionelle Gruppen enthalten sind, die bei einer Verknüpfung der genannten Bausteine stören, so sind diese funktioneilen Gruppen ebenfalls durch geeignete Schutzgruppen blockiert.Compounds of the general formula I are ultimately obtained after splitting off the protective group SGI in VII (Scheme 3). To enable a more detailed description, the Synthetic schemes, instead of the group T, already have carboxylic acid derivative residues, such as the group —CO-R 1 , a preferred embodiment of the group Z shown. The synthesis with the corresponding group Z runs analogously. In the event that the radicals R 2 , R 3 , R 4 , R 5 , R 6 , Q or A contain functional groups which interfere with the linking of the above-mentioned building blocks, these functional groups are also blocked by suitable protective groups .
Die genannten Kupplungen können mithilfe gängiger Kupplungsreagenzien unter Verwendung der geeignet geschützten Amino- und Carbonsäure-Derivate durchgeführt werden (Y=OH in Formel III und VI). Eine andere Methode besteht in der Verwendung voraktivierter Carbonsäure-Derivate, vorzugsweise von Carbonsäurehalogeniden, symmetrischen oder gemischten Anhydriden oder sogenannter Aktivester (Y= Halogenid, Aktivester, Anhydrid; in Formel III und VI), die üblicherweise zur Acylierung von Aminen verwendet werden. Diese aktivierten Carbonsäure-Derivate können auch in-situ hergestellt werden.The couplings mentioned can be carried out using conventional coupling reagents using the suitably protected amino and carboxylic acid derivatives (Y = OH in formula III and VI). Another method is to use preactivated carboxylic acid derivatives, preferably carboxylic acid halides, symmetrical or mixed anhydrides or so-called active esters (Y = halide, active ester, anhydride; in formula III and VI), which are usually used for the acylation of amines. These activated carboxylic acid derivatives can also be prepared in situ.
Die Kupplungen lassen sich in der Regel in inerten Lösungsmitteln in Gegenwart eines säurebindenden Mittels durchführen, vorzugsweise einer organischen Base wie z.B. Triethylamin, Pyridin, Diisopropylethylamin, N-Methylmorpholin, Chinolin; auch der Zusatz eines Alkali- oder Erdalkalimetallhydroxids, -carbonats oder -hydrogencarbonats oder eines anderen Salzes einer schwachen Säure der Alkali- oder Erdalkalimetalle, vorzugsweise des Kaliums, Natriums, Calciums oder Caesiums kann vorteilhaft sein. Die Reaktionszeit liegt je nach verwendeten Bedingungen zwischen Minuten und 14 Tagen, die Reaktionstemperatur zwischen -40°C und 140°C, vorzugsweise zwischen -20°C und 100°C.The couplings can usually be carried out in inert solvents in the presence of an acid-binding agent, preferably an organic base such as e.g. Triethylamine, pyridine, diisopropylethylamine, N-methylmorpholine, quinoline; the addition of an alkali or alkaline earth metal hydroxide, carbonate or bicarbonate or another salt of a weak acid of the alkali or alkaline earth metals, preferably potassium, sodium, calcium or cesium, can also be advantageous. Depending on the conditions used, the reaction time is between minutes and 14 days, the reaction temperature between -40 ° C and 140 ° C, preferably between -20 ° C and 100 ° C.
Als inerte Lösungsmittel eignen sich z.B. Kohlenwasserstoffe wie Hexan, Heptan, Petrolether, Toluol, Benzol oder Xylol; chlorierte Kohlenwasserstoffe wie Trichlorethylen, 1,2-Dichlorethan,Suitable inert solvents are e.g. Hydrocarbons such as hexane, heptane, petroleum ether, toluene, benzene or xylene; chlorinated hydrocarbons such as trichlorethylene, 1,2-dichloroethane,
Tetrachlorkohlenstoff, Chloroform, Dichlormethan; Alkohole wie Methanol, Ethanol, Isopropanol, n-Propanol, n-Butanol oder tert.- Butanol; Ether wie Diethylether, Methyl-tert.butylether, Diiso- propylether, Tetrahydrofuran, Dioxan; Glycolether wie Ethylen- glycolmonomethylether oder -monoethylether, Ethylenglycoldi- methylether; Ketone wie Aceton, Butanon; Amide wie Dimethylform- amid (DMF) , Dimethylacetamid oder Acetamid; Nitrile wie Aceto- nitril; Sulfoxide wie Dimethylsulfoxid; Carbonsäuren wie Ameisensäure oder Essigsäure; Nitroverbindungen wie Nitromethan oder Nitrobenzol; Ester wie Ethylacetat (Essigester); Wasser; oder Gemische der genannten Lösungsmittel. Als Schutzgruppen SG können alle dem Fachmann aus der Peptidsynthese bekannten und gängigen Schutzgruppen verwendet werden, wie sie auch in den oben genannten Standard-werken beschrieben sind. Die Abspaltung der Schutzgruppen zu den Verbindungen der Formel V, X und I erfolgt ebenfalls nach Bedingungen, wie sie dem Fachmann bekannt sind und z.B. von Greene und Wuts in "Protective Groups in Organic Synthesis", 2nd Edition, Wiley & Sons, 1991, beschrieben sind.Carbon tetrachloride, chloroform, dichloromethane; Alcohols such as methanol, ethanol, isopropanol, n-propanol, n-butanol or tert-butanol; Ethers such as diethyl ether, methyl tert-butyl ether, diisopropyl ether, tetrahydrofuran, dioxane; Glycol ethers such as ethylene glycol monomethyl ether or monoethyl ether, ethylene glycol dimethyl ether; Ketones such as acetone, butanone; Amides such as dimethylformamide (DMF), dimethylacetamide or acetamide; Nitriles such as acetonitrile; Sulfoxides such as dimethyl sulfoxide; Carboxylic acids such as formic acid or acetic acid; Nitro compounds such as nitromethane or nitrobenzene; Esters such as ethyl acetate (ethyl acetate); Water; or mixtures of the solvents mentioned. Protective groups SG which can be used are all of the conventional protective groups known to the person skilled in the art from peptide synthesis, as are also described in the above-mentioned standard works. The protective groups are split off to give the compounds of the formulas V, X and I likewise under conditions known to the person skilled in the art and described, for example, by Greene and Wuts in "Protective Groups in Organic Synthesis", 2nd Edition, Wiley & Sons, 1991 are.
Bei SG3 und SG5 handelt es sich um sogenannte N-terminale Amino- schutzgruppen; bevorzugt sind hier Boc, Fmoc, Benzyloxycarbonyl (Z), Acetyl, Mtr.SG3 and SG5 are so-called N-terminal amino protecting groups; Boc, Fmoc, benzyloxycarbonyl (Z), acetyl, Mtr are preferred here.
SGI, SG2 und SG4 stehen für geeignete C-terminale Hydroxyschutz- gruppen, bevorzugt sind hier Cι-C-Alkyl wie z.B. Methyl, Ethyl, tert-Butyl, oder auch Benzyl oder Trityl, oder -insbesondere für SGI- auch polymer gebundene Schutzgruppen in Form der handelsüblichen Poylstyrol-Harze wie z.B. 2-Chlortritylchloridharz oder Wang-Harz (Fa. Bachern, Fa. Novabiochem) .SGI, SG2 and SG4 stand for suitable C-terminal hydroxyl protective groups, preference being given here to C 1 -C 6 -alkyl, such as Methyl, ethyl, tert-butyl, or also benzyl or trityl, or - especially for SGI - also polymer-bound protective groups in the form of the commercially available polystyrene resins, such as 2-chlorotrityl chloride resin or Wang resin (Bachern, Novabiochem).
Die Abspaltung säurelabiler Schutzgruppen (z.B. Boc, tert. Butyl, Mtr, Trityl) kann - je nach verwendeter Schutzgruppe - mit organischen Säuren wie Trifluoressigsäure (TFA) , Trichloressig- säure, Triflurethanol oder auch anorganischen Säuren wie Per- Chlorsäure, Salzsäure oder Schwefelsäure, Sulfonsäuren wie Benzol- oder p-Toluolsulfonsäure erfolgen, wobei die Säuren generell im Überschuß eingesetzt werden. Im Falle von Trityl kann der Zusatz von Thiolen wie z.B. Thioanisol, Ethandithiol oder Thiophenol vorteilhaft sein. Die Anwesenheit eines zusätz- liehen inerten Lösungsmittels ist möglich, aber nicht immer erforderlich. Als inerte Lösungsmittel eignen sich vorzugsweise organische Lösungsmittel, beispielsweise Carbonsäuren wie Essigsäure; Ether wie THF oder Dioxan; Amide wie DMF oder Dimethyl- acetamid; halogenierte Kohlenwasserstoffe wie Dichlormethan; Alkohole wie Methanol, Isopropanol; oder Wasser. Es kommen auch Gemische der genannten Lösungsmittel in Frage. Die Reaktionstemperatur für diese Umsetzungen liegt zwischen -10°C und 50°C, vorzugsweise arbeitet man in einem Bereich zwischen 0°C und 30°C.Depending on the protective group used, the cleavage of acid-labile protective groups (eg Boc, tert-butyl, Mtr, trityl) can be carried out using organic acids such as trifluoroacetic acid (TFA), trichloroacetic acid, triflurethanol or else inorganic acids such as perchloric acid, hydrochloric acid or sulfuric acid, Sulfonic acids such as benzene or p-toluenesulfonic acid take place, the acids being generally used in excess. In the case of trityl, the addition of thiols such as e.g. Thioanisole, ethanedithiol or thiophenol may be advantageous. The presence of an additional inert solvent is possible, but not always necessary. Suitable inert solvents are preferably organic solvents, for example carboxylic acids such as acetic acid; Ethers such as THF or dioxane; Amides such as DMF or dimethyl acetamide; halogenated hydrocarbons such as dichloromethane; Alcohols such as methanol, isopropanol; or water. Mixtures of the solvents mentioned are also suitable. The reaction temperature for these reactions is between -10 ° C and 50 ° C, preferably in a range between 0 ° C and 30 ° C.
Basenlabile Schutzgruppen wie Fmoc werden durch Behandlung mit organischen Aminen wie Dimethylamin, Diethylamin, Morpholin, Piperidin als 5-50% Lösungen in CH2C1 oder DMF gespalten. Die Reaktionstemperatur für diese Umsetzungen liegt zwischen -10°C und 50°C, vorzugsweise arbeitet man in einem Bereich zwischen 0°C und 30°C. Säureschutzgruppen wie Methyl oder Ethyl werden bevorzugt durch basische Hydrolyse in einem inerten Lösungsmittel gespalten. Als Basen werden bevorzugt Alkali- oder Erdalkalimetallhydroxide, vorzugsweise NaOH, KOH oder LiOH verwendet; als Lösungsmittel kommen alle gängigen inerten Lösungsmittel wie z.B. Kohlenwasserstoffe wie Hexan, Heptan, Petrolether, Toluol, Benzol oder Xylol; chlorierte Kohlenwasserstoffe wie Trichlorethylen, 1,2-Dichlor- ethan, Tetrachlorkohlenstoff, Chloroform, Dichlormethan; Alkohole wie Methanol, Ethanol, Isopropanol, n-Propanol, n-Butanol oder tert.-Butanol; Ether wie Diethylether, Methyl-tert .butylether, Diisopropylether, Tetrahydrofuran, Dioxan; Glycolether wie Ethylenglycolmonomethylether oder -monoethylether, Ethylenglycol- dimethylether; Ketone wie Aceton, Butanon; Amide wie Dimethyl- formamid (DMF) , Dirnethylacetamid oder Acetamid; Nitrile wie Acetonitril; Sulfoxide wie Dimethylsulfoxid; Nitroverbindungen wie Nitromethan oder Nitrobenzol; Wasser oder Gemische der genannten Lösungsmittel zum Einsatz. Der Zusatz eines Phasen- transferkatalysators kann -je nach verwendetem Lösungsmittel bzw. -gemischs von Vorteil sein. Die Reaktionstemperatur für diese Umsetzungen liegt generell zwischen -10°C und 100°C.Base-labile protective groups such as Fmoc are cleaved by treatment with organic amines such as dimethylamine, diethylamine, morpholine, piperidine as 5-50% solutions in CH 2 C1 or DMF. The reaction temperature for these reactions is between -10 ° C and 50 ° C, preferably in a range between 0 ° C and 30 ° C. Acid protecting groups such as methyl or ethyl are preferably cleaved by basic hydrolysis in an inert solvent. Alkali or alkaline earth metal hydroxides, preferably NaOH, KOH or LiOH, are preferably used as bases; all common inert solvents such as hydrocarbons such as hexane, heptane, petroleum ether, toluene, benzene or xylene are used as solvents; chlorinated hydrocarbons such as trichlorethylene, 1,2-dichloroethane, carbon tetrachloride, chloroform, dichloromethane; Alcohols such as methanol, ethanol, isopropanol, n-propanol, n-butanol or tert-butanol; Ethers such as diethyl ether, methyl tert-butyl ether, diisopropyl ether, tetrahydrofuran, dioxane; Glycol ethers such as ethylene glycol monomethyl ether or monoethyl ether, ethylene glycol dimethyl ether; Ketones such as acetone, butanone; Amides such as dimethylformamide (DMF), dirthylacetamide or acetamide; Nitriles such as acetonitrile; Sulfoxides such as dimethyl sulfoxide; Nitro compounds such as nitromethane or nitrobenzene; Water or mixtures of the solvents mentioned are used. The addition of a phase transfer catalyst can be advantageous, depending on the solvent or mixture used. The reaction temperature for these reactions is generally between -10 ° C and 100 ° C.
Hydrogenolytisch abspaltbare Schutzgruppen wie Benzyloxycarbonyl (Z) oder Benzyl können z.B. durch Hydrogenolyse in Gegenwart eines Katalysators (z.B. eines Edelmetallkatalysators auf Aktiv- kohle als Träger) abgespalten werden. Als Lösungsmittel eignen sich die oben angegebenen, insbesondere Alkohole wie Methanol, Ethanol; Amide wie DMF oder Dimethylacetamid; Ester wie Ethyl- acetat. Die Hydrogenolyse wird in der Regel bei einem Druck von l-200bar und Temperaturen zwischen 0° und 100°C durchgeführt; der Zusatz einer Säure wie z.B. Essigsäure oder Salzsäure kann vorteilhaft sein. Als Katalysator wird bevorzugt 5-10% Pd auf Aktivkohle verwendet. Protective groups which can be split off hydrogenolytically, such as benzyloxycarbonyl (Z) or benzyl, can be split off, for example, by hydrogenolysis in the presence of a catalyst (for example a noble metal catalyst on activated carbon as a support). Suitable solvents are those given above, in particular alcohols such as methanol, ethanol; Amides such as DMF or dimethylacetamide; Esters such as ethyl acetate. The hydrogenolysis is usually carried out at a pressure of 1-200 bar and temperatures between 0 ° and 100 ° C; the addition of an acid such as acetic acid or hydrochloric acid can be advantageous. 5-10% Pd on activated carbon is preferably used as the catalyst.
Die Verbindungen der Formel II, III und VIII bzw. die Ausgangsmaterialien zu ihrer Darstellung sind entweder käuflich oder nach bekannten Methoden herstellbar. So können z.B. ß-Aryl- bzw. Heteroaryl-Aminosäuren nach der Methode von Johnson et al., J. Am. Chem. Soc, 299, 1936, oder Edwards et al., J. Org. Chem. 1979, 44, 3136-3140, aus einem Aryl- bzw. Heteroarylaldehyd, Malonsäure und Ammoniumacetat synthetisiert werden. The compounds of the formulas II, III and VIII or the starting materials for their preparation are either commercially available or can be prepared by known methods. For example, β-aryl or heteroaryl amino acids can be prepared by the method of Johnson et al., J. Am. Chem. Soc, 299, 1936, or Edwards et al., J. Org. Chem. 1979, 44, 3136-3140, can be synthesized from an aryl or heteroaryl aldehyde, malonic acid and ammonium acetate.
Cole beschreibt in Tetrahedron 1994, 50, 9517-9582, generell die Synthese von ß-Aminosäuren. Eine Methode zur enantioselektiven Synthese von ß-Aminosäuren wird z.B. von Enders, Angew. Chem. Int. Ed. Engl., 1995, 34, 455-457, beschrieben. Die Darstellung von enantiomerenreinem 3-Pyridinyl-ß-alanin ist von Rico et al . ,Cole generally describes the synthesis of β-amino acids in Tetrahedron 1994, 50, 9517-9582. A method for the enantioselective synthesis of β-amino acids is e.g. by Enders, Angew. Chem. Int. Ed. Engl., 1995, 34, 455-457. The representation of enantiomerically pure 3-pyridinyl-β-alanine is from Rico et al. .
J. Org. Chem., 1993, 58, 7948-7951 beschrieben, 3-Ethinyl-ß-alanin kann gemäß Zablocki et al . , J. Med. Chem. 1995, 38, 2378-2394 hergestellt werden. Geeignete Diaminopropionsäure-Derivate sind ebenfalls käuflich oder können gemäß WO 97/37655 einfach her- gestellt werden.J. Org. Chem., 1993, 58, 7948-7951, 3-ethynyl-β-alanine can be according to Zablocki et al. , J. Med. Chem. 1995, 38, 2378-2394. Suitable diaminopropionic acid derivatives are also commercially available or can simply be prepared in accordance with WO 97/37655.
Die Überführung der freien ß-Aminosäuren bzw. Diaminopropionsäure- Derivate in die entsprechend N- oder C-terminal geschützten Derivate läßt sich nach gängigen Methoden der organischen Chemie durchführen, wie es z.B. von Bodanszky oder Greene in den genannten Standardwerken beschrieben ist.The conversion of the free ß-amino acids or diaminopropionic acid derivatives into the correspondingly N- or C-terminally protected derivatives can be carried out according to common methods in organic chemistry, such as e.g. by Bodanszky or Greene in the standard works mentioned.
Amino-Heteroarylcarbonsäuren bzw. Amino-Heteroarylcarbonsäure- ester der allgemeinen Formel:Amino-heteroarylcarboxylic acids or amino-heteroarylcarboxylic acid esters of the general formula:
XI XII XV-aXI XII XV-a
die als Ausgangsmaterialien in der Synthese von Verbindungen der Formel I Verwendung finden, sind entweder käuflich oder können gemäß der folgenden Beispiele dargestellt werden:which are used as starting materials in the synthesis of compounds of the formula I are either commercially available or can be prepared according to the following examples:
2-Amino-l,3-thiazol-5-carbonsäureethylester in Kushner et al., J. Org. Chem. 1948, 13, 834ff; 2-Amino-4-pyridincarbonsäure- methylester in Podany et al., J. Org. Chem. 1986, 51, 2988-2994; 5-Amino-3-pyridincarbonsäuremethylester in Hawkins et al., J. Org. Chem. 1949, 14, 328-332; 4-Amino-2-pyrimidincarbonsäure- methylester in DE 2848912, 6-Amino-4-pyrimidin-carbonsäure- methylester in Zh. Org. Khim. 1981, 17, 312-317; 5-Amino-l,3- thiazol-2-carbonsäureethylester in Adams et al., J. Chem. Soc. 1956 , 1870-1873 ; 4- (Aminomethyl ) -2-thiophencarbonsäuremethylester in Peschke et al., Bioorg. Med. Chem. Lett. 1997, 7, 1969-1972; 2-Amino-l, 3-oxazol-4-carbonsäure in Foulis et al., J. Med. Chem. 5 1971, 14, 1075-1077; 4-Aminopyridin-2-carbonsäuremethylester in Mostier et al . , J. Org. Chem. 1955, 20, 283-285; 2-Amino- pyrimidin-3-carbonsäuremethylester in Liebigs Ann. Chem. 1965, 209-211; 5-Amino-l, 3 , 4-thiadiazol-5-carbonsäure in Liebigs Ann. Chim. 1963, 3; 5-Amino-l, 3 , 4-triazol-5-carbonsäure in US 3023210; 0 4-Aminopyrrol-2-carbonsäure in J. Med. Chem. 1983, 26, 1042; l-Methyl-3-aminopyrazol-5-carbonsäure in Acta Chem. Scand. 1990, 44, 74; l-Methyl-5-amino-3-carbonsäure in Lee et al . , J. Org. Chem. 1989, 54, 428.2-amino-1,3-thiazole-5-carboxylic acid ethyl ester in Kushner et al., J. Org. Chem. 1948, 13, 834ff; 2-amino-4-pyridinecarboxylic acid methyl ester in Podany et al., J. Org. Chem. 1986, 51, 2988-2994; 5-Amino-3-pyridinecarboxylic acid methyl ester in Hawkins et al., J. Org. Chem. 1949, 14, 328-332; 4-Amino-2-pyrimidine carboxylic acid methyl ester in DE 2848912, 6-amino-4-pyrimidine carboxylic acid methyl ester in Zh. Org. Khim. 1981, 17, 312-317; 5-amino-l, 3- ethyl thiazole-2-carboxylate in Adams et al., J. Chem. Soc. 1956, 1870-1873; Methyl 4- (aminomethyl) -2-thiophenecarboxylate in Peschke et al., Bioorg. Med. Chem. Lett. 1997, 7, 1969-1972; 2-amino-1,3-oxazole-4-carboxylic acid in Foulis et al., J. Med. Chem. 5 1971, 14, 1075-1077; 4-aminopyridine-2-carboxylic acid methyl ester in Mostier et al. , J. Org. Chem. 1955, 20, 283-285; 2-Amino-pyrimidine-3-carboxylic acid methyl ester in Liebigs Ann. Chem. 1965, 209-211; 5-amino-1,3,4-thiadiazole-5-carboxylic acid in Liebigs Ann. Chim. 1963, 3; 5-amino-1,3,4-triazole-5-carboxylic acid in US 3023210; 0 4-aminopyrrole-2-carboxylic acid in J. Med. Chem. 1983, 26, 1042; l-methyl-3-aminopyrazole-5-carboxylic acid in Acta Chem. Scand. 1990, 44, 74; l-methyl-5-amino-3-carboxylic acid in Lee et al. , J. Org. Chem. 1989, 54, 428.
Die Überführung von Amino-Heteroarylcarbonsäuren bzw. Amino- Heteroarylcarbonsäureester der allgemeinen Formel:The transfer of amino-heteroarylcarboxylic acids or amino-heteroarylcarboxylic acid esters of the general formula:
XI XIIXI XII
in Verbindungen der allgemeinen Formel:in compounds of the general formula:
XIII XIVXIII XIV
kann nach dem Fachmann bekannten Methoden erfolgen, die z.B. in WO 97/08145 beschrieben sind. Diese Bausteine können dann entweder direkt -im Fall der entsprechenden freien Carbonsäurenoder nach Abspaltung der Schutzgruppe SG4 mit Verbindungen der allgemeinen Formel V zu VII (Schema 1) bzw. mit VIII zu IX umgesetzt werden (für Y=OH entspricht Verbindung VI Verbindung XIII) .can be carried out according to methods known to those skilled in the art, e.g. are described in WO 97/08145. These building blocks can then be reacted either directly - in the case of the corresponding free carboxylic acids or after splitting off the protective group SG4 - with compounds of the general formula V to VII (Scheme 1) or with VIII to IX (for Y = OH, compound VI corresponds to compound XIII).
In den Schemata 4-7 sind eine Reihe der Methoden zur Einführung von A exemplarisch beschrieben, wobei jeweils Reaktionsbedingungen verwendet wurden, wie sie für die jeweiligen Umsetzungen bekannt und geeignet sind. Dabei kann auch von an sich bekannten, hier nicht erwähnten Varianten Gebrauch gemacht werden. Harnstoffe bzw. Thioharnstoffe (AE-1 bis AE-3) lassen sich nach gängigen Methoden der organischen Chemie herstellen, z.B. wie in Schema 4 dargestellt, durch Umsetzung eines Isocyanats bzw. eines Thioisocyanats mit einem Amin, gegebenenfalls in einem inerten 5 Lösungsmittel unter Erwärmen (Houben-Weyl Band VIII, 157ff.)A number of the methods for introducing A are described by way of example in schemes 4-7, reaction conditions being used as are known and suitable for the respective reactions. Use can also be made of variants which are known per se and are not mentioned here. Urea or thiourea (AE-1 to AE-3) can be prepared by conventional methods in organic chemistry, for example as shown in Scheme 4, by reacting an isocyanate or a thioisocyanate with an amine, optionally in an inert solvent, with heating (Houben-Weyl Volume VIII, 157ff.)
Schema 5 zeigt beispielhaft die Darstellung von Verbindungen des Typs AE-4, wie es z.B. von Blakemoore et al. in Eur. J. Med. Chem. 1987 (22) 2, 91-100, oder von Misra et al . in Bioorg. Med. 10 Chem. Lett. 1994 4 (18), 2165-2170 beschrieben ist.Scheme 5 shows an example of the representation of compounds of the type AE-4, e.g. by Blakemoore et al. in Eur. J. Med. Chem. 1987 (22) 2, 91-100, or by Misra et al. in Bioorg. Med. 10 Chem. Lett. 1994 4 (18), 2165-2170.
Unsubstituierte oder cycl. Guanidin-Derivate der allgemeinen Formel AE-5 und AE-6 lassen sich mittels käuflicher oder einfach zugänglicher Reagenzien herstellen, wie z.B. in Synlett 1990, 15 745, J. Org. Chem. 1992, 57, 2497, Bioorg. Med. Chem. 1996, 6, 1185-1208; Bioorg. Med. Chem. 1998, 1185, oder Synth. Comm. 1998, 28, 741-746, beschrieben.Unsubstituted or cycl. Guanidine derivatives of the general formula AE-5 and AE-6 can be prepared using commercially available or easily accessible reagents, such as e.g. in Synlett 1990, 15 745, J. Org. Chem. 1992, 57, 2497, Bioorg. Med. Chem. 1996, 6, 1185-1208; Bioorg. Med. Chem. 1998, 1185, or Synth. Comm. 1998, 28, 741-746.
Die Darstellung von Verbindungen der allgemeinen Formel AE-7 kann 20 analog zu US 3,202,660, Verbindungen der Formel AE-9, AE-10,Compounds of the general formula AE-7 can be represented analogously to US Pat. No. 3,202,660, compounds of the formula AE-9, AE-10,
AE-11 und AE-12 analog zu WO 97/08145 erfolgen. Verbindungen der Formel AE-8 lassen sich, wie in Schema 6 gezeigt, z.B. gemäß der von Perkins et al., Tetrahedron Lett. 1999, 40, 1103-1106, beschriebenen Methode herstellen. Schema 6 gibt eine Übersicht über 25 die Synthese der genannten Verbindungen.AE-11 and AE-12 take place analogously to WO 97/08145. Compounds of formula AE-8, as shown in Scheme 6, e.g. according to the method described by Perkins et al., Tetrahedron Lett. 1999, 40, 1103-1106. Scheme 6 gives an overview of 25 the synthesis of the compounds mentioned.
Verbindungen der allgemeinen Formel AE-13 lassen sich analog zu Froeyen et al . , Phosphorus Sulfur Silicon Relat. Eiern. 1991, 63, 283-293, AE-14 analog zu Yoneda et al., Heterocycles 1998, 15 0 No-1, Spec. Issue, 341-344, wie in Schema 7 dargestellt, herstellen. Die Darstellung entsprechender Verbindungen kann auch analog WO 97/36859 erfolgen.Compounds of the general formula AE-13 can be analogous to Froeyen et al. , Phosphorus Sulfur Silicon Relat. Eggs. 1991, 63, 283-293, AE-14 analogous to Yoneda et al., Heterocycles 1998, 15 0 No-1, Spec. Prepare Issue, 341-344 as shown in Scheme 7. Corresponding connections can also be represented analogously to WO 97/36859.
Wie in Schema 8 gezeigt, können auch alternativ Verbindungen 5 der allgemeinen Formel IX mit XV zu Verbindungen der allgemeinen Formel XVI umgesetzt werden, die dann nach Abspaltung der Schutzgruppe SG5 nach den in WO 97/08145 und Schemata 2-5 gezeigten Methoden in Verbindungen des Typs VIII überführt werden. Für den Fall R1 gleich Cι-C4-Alkoxy oder Benzyloxy entsprechen die Ver- 0 bindungen der allgemeinen Formel VIII direkt den Verbindungen des Typs I .As shown in Scheme 8, alternatively compounds 5 of the general formula IX can also be reacted with XV to give compounds of the general formula XVI which, after splitting off the protective group SG5, can then be converted into compounds of the Type VIII are transferred. In the case R 1 is C 1 -C 4 -alkoxy or benzyloxy, the compounds of the general formula VIII correspond directly to the compounds of type I.
5 Ü u co co o o5 Ü u co co oo
I I o PI I o P
II II o u I ω < x X u uII II o u I ω <x X u u
I I σ σ i II I σ σ i I
υ υ
-i-Z -_ z-i-Z -_ z
>-» Λ> - »Λ
noch Schema 6 : Scheme 6:
mit : ankondensiertes cycl. ystem wie Aryl oder Hetaryl with: condensed cycl. ystem such as aryl or hetaryl
AE-8AE-8
CH,! AE-9CH ,! AE-9
Acetonacetone
R-NH2 R-NH 2
HN " H.C« DIPEAHN "H.C« DIPEA
HN^N — (CH 2)f-Q-(CH2)e-(C=0)-OSG4 HN^N-(CH 2)-Q-(CH2)β-{C=0)-OSG4 HHN ^ N - (CH 2 ) f -Q- (CH 2 ) e - (C = 0) -OSG4 HN ^ N- (CH 2 ) -Q- (CH 2 ) β - {C = 0) -OSG4 H
Dloxan/H 20 HDloxan / H 2 0 H
AE-10 AE-10
noch Schema 6: Scheme 6:
Rückfluß Reflux
AE-12 AE-11 AE-12 AE-11
Schema 7 :Scheme 7:
AE-14 AE-14
Die Erfindung betrifft ferner Arzneimittelzubereitungen zur peroralen und parenteralen Anwendung, enthaltend neben den üblichen Arzneimittelhilfsstoffen, mindestens eine Verbindung der Formel I . The invention further relates to pharmaceutical preparations for oral and parenteral use, containing, in addition to the usual pharmaceutical excipients, at least one compound of the formula I.
Die erfindungsgemäßen Verbindungen können in üblicher Weise oral oder parenteral (subkutan, intravenös, intramuskulär, intra- pertoneal) verabreicht werden. Die Applikation kann auch mit Dämpfen oder Sprays durch den Nasen-Rachenraum erfolgen.The compounds according to the invention can be administered in the usual way orally or parenterally (subcutaneously, intravenously, intramuscularly, intrapertonally). It can also be applied with vapors or sprays through the nasopharynx.
Die Dosierung hängt vom Alter, Zustand und Gewicht des Patienten sowie von der Applikationsart ab. In der Regel beträgt die tägliche Wirkstoffdosis zwischen etwa 0,5 und 50 mg/kg Körpergewicht bei oraler Gabe und zwischen etwa 0,1 und 10 mg/kg Körpergewicht bei parenteraler Gabe.The dosage depends on the age, condition and weight of the patient and on the type of application. As a rule, the daily dose of active substance is between approximately 0.5 and 50 mg / kg body weight when administered orally and between approximately 0.1 and 10 mg / kg body weight when administered parenterally.
Die neuen Verbindungen können in den gebräuchlichen galenischen Applikationsformen fest oder flüssig angewendet werden, z.B. als Tabletten, Filmtabletten, Kapseln, Pulver, Granulate, Dragees, Suppositorien, Lösungen, Salben, Cremes oder Sprays. Diese werden in üblicher Weise hergestellt. Die Wirkstoffe können dabei mit den üblichen galenischen Hilfsmitteln wie Tablettenbindern, Füllstoffen, Konservierungsmitteln, Tablettensprengmitteln, Fließ- reguliermitteln, Weichmachern, Netzmitteln, Dispergiermitteln, Emulgatoren, Lösungsmitteln, Retardierungsmitteln, Antioxidantien und/oder Treibgasen verarbeitet werden (vgl. H. Sucker et al.: Pharmazeutische Technologie, Thieme-Verlag, Stuttgart, 1991) . Die so erhaltenen Applikationsformen enthalten den Wirkstoff normalerweise in einer Menge von 0,1 bis 90 Gew. -%.The new compounds can be used in the customary pharmaceutical application forms, solid or liquid, e.g. as tablets, film-coated tablets, capsules, powders, granules, dragees, suppositories, solutions, ointments, creams or sprays. These are manufactured in the usual way. The active ingredients can be processed with the usual pharmaceutical auxiliaries such as tablet binders, fillers, preservatives, tablet disintegrants, flow regulators, plasticizers, wetting agents, dispersants, emulsifiers, solvents, retardants, antioxidants and / or propellants (see H. Sucker et al. : Pharmaceutical Technology, Thieme-Verlag, Stuttgart, 1991). The administration forms thus obtained normally contain the active ingredient in an amount of 0.1 to 90% by weight.
Ferner betrifft die Erfindung die Verwendung der Verbindungen der Formel I zur Herstellung von Arzneimitteln zur Behandlung von Krankheiten. Die Verbindungen der Formel I können zur Behandlung von humanen und tierischen Krankheiten verwendet werden. Die Verbindungen der Formel I binden an Integrinrezeptoren und können somit als Integrin-Rezeptorantagonisten und zur Herstellung von Arzneimitteln zur Behandlung von Krankheiten, in die ein Integrinrezeptor involviert ist, verwendet werden.The invention further relates to the use of the compounds of the formula I for the production of medicaments for the treatment of diseases. The compounds of formula I can be used for the treatment of human and animal diseases. The compounds of the formula I bind to integrin receptors and can thus be used as integrin receptor antagonists and for the preparation of medicaments for the treatment of diseases in which an integrin receptor is involved.
Bevorzugt binden die Verbindungen der Formel I an denαvß3- Integrinrezeptor und können somit bevorzugt als Antagonisten des αvß3-Integrinrezeptors und zur Behandlung von Krankheiten, in die der αvß3-Integrinrezeptor involviert ist, verwendet werden.The compounds of the formula I preferably bind to the α v β 3 integrin receptor and can thus preferably be used as antagonists of the αv β 3 integrin receptor and for the treatment of diseases in which the α v β 3 integrin receptor is involved.
Die Verbindungen der Formel I werden bevorzugt zur Behandlung folgender Krankheiten verwendet: Kardiovaskuläre Erkrankungen wie Atherosklerose, Restenose nach Gefäßverletzung, und Angioplastie (Neointimabildung, Glattmuskelzeilmigration und Proliferation) ,The compounds of the formula I are preferably used for the treatment of the following diseases: Cardiovascular diseases such as atherosclerosis, restenosis after vascular injury, and angioplasty (neointima formation, smooth muscle line migration and proliferation),
akutes Nierenversagen,acute kidney failure,
Angiogenese-assoziierte Mikroangiopathien wie beispielsweise diabetische Angiopathien oder Retinopathie oder rheumatische Arthritis,Angiogenesis-associated microangiopathies such as diabetic angiopathies or retinopathy or rheumatic arthritis,
Blutplättchen vermittelter Gefäßverschluß, arterielle Thrombose,Platelet mediated vascular occlusion, arterial thrombosis,
Schlaganfall, Reperfusionsschäden nach Myokardinfarkt oder Schlaganfall,Stroke, reperfusion damage after myocardial infarction or stroke,
Krebserkrankungen, wie beispielsweise bei der Tumormetastasierung oder beim Tumorwachstum (tumorinduzierte Angiogenese) ,Cancer, such as tumor metastasis or tumor growth (tumor-induced angiogenesis),
Osteoporose (Knochenresorption nach Chemotaxis und Adhäsion von Osteoclasten an Knochenmatrix) ,Osteoporosis (bone resorption after chemotaxis and adhesion of osteoclasts to bone matrix),
Bluthochdruck, Psoriasis, Hyperparathyroismus, Paget'sche Erkrankung, maligne Hypercalcemie, metastatische osteolytische Läsionen, Entzündung, Wundheilung, Herzinsuffizienz, Kongestives Herzversagen CHF, sowie beiHypertension, psoriasis, hyperparathyroism, Paget's disease, malignant hypercalcemia, metastatic osteolytic lesions, inflammation, wound healing, heart failure, congestive heart failure CHF, as well as in
anti-viraler, anti-parasitärer oder anti-bakterieller Therapie und Prophylaxe (Adhäsion und Internalisierung) .anti-viral, anti-parasitic or anti-bacterial therapy and prophylaxis (adhesion and internalization).
Vorteilhafterweise können die Verbindungen der Formel I in Kombination mit mindestens einer weiteren Verbindung verabreicht werden, um in einer Reihe von Indikationen eine verbesserte Heilwirkung zu erreichen. Diese weiteren Verbindungen können den gleichen oder einem anderen Wirkmechanismus wie die Verbindungen der Formel I aufweisen.The compounds of the formula I can advantageously be administered in combination with at least one further compound in order to achieve an improved curative effect in a number of indications. These further compounds can have the same or a different mode of action as the compounds of the formula I.
Die Arzneimittelzubereitungen können daher neben den Verbindungen der Formel I und den üblichen Arzneimittelhilfsstoffen mindestens eine weitere Verbindung, abhängig von der Indikation jeweils aus einer der nachstehenden 10 Gruppen ausgewählt, enthalten.In addition to the compounds of the formula I and the customary pharmaceutical excipients, the pharmaceutical preparations can therefore contain at least one further compound, selected from one of the 10 groups below, depending on the indication.
Gruppe 1:Group 1:
Inhibitoren der Blutplättchenadhäsion, -aktivierung oder -aggre- gation, wie beispielsweise Acetylsalicylsäure, Lysinacetylsalicy- lat, Pilacetym, Dipyridamol, Abciximab, Thromboxane-Antagonisten, Fibrinogen-Antagonisten, wie beispielsweise Tirofiban, oder Inhibitoren der ADP-induzierten Aggregation wie beispielsweise Ticlo- pidin oder Clopidogrel,Inhibitors of platelet adhesion, activation or aggregation, such as, for example, acetylsalicylic acid, lysine acetylsalicylic, pilacetym, dipyridamole, abciximab, thromboxane antagonists, fibrinogen antagonists, for example tirofiban, or inhibitors of ADP inhibitors such as pidin or clopidogrel,
Antikoagulantia, die die Thrombinaktivität oder -bildung verhindern, wie beispielsweise Inhibitoren von Ha, Xa, Xla, IXa oder VIIa, Antagonisten von blutplättchenaktivierenden Verbindungen und Selectin-AntagonistenAnticoagulants that prevent thrombin activity or formation, such as inhibitors of Ha, Xa, Xla, IXa or VIIa, antagonists of platelet activating compounds and selectin antagonists
zur Behandlung von Blutblättchenvermitteltem vaskulärem Verschluß oder Thrombose, oderfor the treatment of platelet mediated vascular occlusion or thrombosis, or
Gruppe 2 :Group 2:
Inhibitoren der Blutplättchenaktivierung oder -aggregation, wie beispielsweise GPIIb/IIIa-Antagonisten, Thrombin- oder Faktor Xa-Inhibitors of platelet activation or aggregation, such as, for example, GPIIb / IIIa antagonists, thrombin or factor Xa
Inhibitoren oder ADP-Rezeptor-Antagonisten, Serin-Protease Inhibitoren,Inhibitors or ADP receptor antagonists, serine protease inhibitors,
Fibrinogen-senkende Verbindungen,Fibrinogen-lowering compounds,
Selectin-Antagonisten,Selectin antagonists,
Antagonisten von ICAM-1 oder VCAM-1Antagonists of ICAM-1 or VCAM-1
Inhibitoren der Leukozytenadhäsion Inhibitoren der Gefäßwandtransmigration,Inhibitors of leukocyte adhesion inhibitors of vascular wall transmigration,
Fibrinolyse-modulierende Verbindungen, wie beispielsweise Strep- tokinase, tPA, Plasminogenaktivierungs-Stimulantien, TAFI-Inhibi- toren, Xla Inhibitoren oder PAI-1-Antagonisten,Fibrinolysis-modulating compounds, such as streptokinase, tPA, plasminogen activation stimulants, TAFI inhibitors, Xla inhibitors or PAI-1 antagonists,
Inhibitoren von Komplementfaktoren, Endothelinrezeptor-Antagonisten,Inhibitors of complement factors, endothelin receptor antagonists,
Tyrosinkinase-Inhibitoren,Tyrosine kinase inhibitors,
Antioxidantien undAntioxidants and
Interleukin 8 AntagonistenInterleukin 8 antagonists
zur Behandlung von Myokardinfarkt oder Schlaganfall, oderfor the treatment of myocardial infarction or stroke, or
Gruppe 3 :Group 3:
Endothelinantagonisten,Endothelin antagonists,
ACE-Inhibitoren, Angiotensinrezeptorantagonisten,ACE inhibitors, angiotensin receptor antagonists,
Endopeptidase Inhibitoren,Endopeptidase inhibitors,
Beta-Blocker,Beta blocker,
Kalziumkanal-Antagonisten,Calcium channel antagonists,
Phosphodiesterasehemmer und CaspaseinhibitorenPhosphodiesterase inhibitors and caspase inhibitors
zur Behandlung von kongestiven Herzversagen, oderfor the treatment of congestive heart failure, or
Gruppe 4 : Thrombininhibitoren,Group 4: thrombin inhibitors,
Inhibitoren des Faktors Xa,Inhibitors of factor Xa,
Inhibitoren des Koagulationsweges der zur Thrombinbildung führt, wie beispielsweise Heparin oder niedermolekulare Heparine, Inhibitoren der Blutplättchenadhäsion, -aktivierung oder -aggre- gation, wie beispielsweise GPllb-lIIa-Antagonisten oder Antagonisten der durch vWF oder GPlb vermittelten Blutplättchenadhäsiion und Aktivierung,Inhibitors of the coagulation pathway leading to thrombin formation, such as heparin or low molecular weight heparins, inhibitors of platelet adhesion, activation or aggregation, such as, for example, GPllb-lIIa antagonists or antagonists of platelet adhesion and activation mediated by vWF or GPlb,
Endothelinrezeptor-Antagonisten, Stickstoffoxidsynthasehemmer, CD44-Antagonisten, Selectin-Antagonisten, MCP-1-Antagonisten,Endothelin receptor antagonists, nitric oxide synthase inhibitors, CD44 antagonists, selectin antagonists, MCP-1 antagonists,
Inhibitoren der Signaltransduktion in proliferierenden Zellen, Antagonisten der durch EGF, PDGF, VEGF oder bFGF vermittelten Zellantwort und AntioxidantienInhibitors of signal transduction in proliferating cells, antagonists of the cell response mediated by EGF, PDGF, VEGF or bFGF and antioxidants
zur Behandlung von Restenose nach Gefäßverletzung oder Stentim- plantation, oderfor the treatment of restenosis after vascular injury or stent implantation, or
Gruppe 5 : Antagonisten der durch EGF, PDGF, VEGF oder bFGF vermitteltenGroup 5: antagonists mediated by EGF, PDGF, VEGF or bFGF
Zellantwort,Cell response,
Heparin oder niedermolekulare Heparine oder weitere GAGs,Heparin or low molecular weight heparins or other GAGs,
Inhibitoren von MMPs,Inhibitors of MMPs,
Selectin-Antagonisten, Endothelin-Antagonisten,Selectin antagonists, endothelin antagonists,
ACE-Inhibitoren,ACE inhibitors,
Angiotensinrezeptor-Antagonisten undAngiotensin receptor antagonists and
Glycosilierungsheinmer oder AGE-Bildungs-Inhibitoren und Antagonisten Ihrer Rezeptoren, wie beispielsweise RAGE,Glycosylation inhibitors or AGE formation inhibitors and antagonists of your receptors, such as RAGE,
zur Behandlung von diabetischen Angiopathien oderfor the treatment of diabetic angiopathies or
Gruppe 6: fettsenkende Verbindungen, Selectin-Antagonisten,Group 6: fat-lowering compounds, selectin antagonists,
Antagonisten von ICAM-1 oder VCAM-1Antagonists of ICAM-1 or VCAM-1
Heparin oder niedermolekulare Heparine oder weitere GAGs,Heparin or low molecular weight heparins or other GAGs,
Inhibitoren von MMPs,Inhibitors of MMPs,
Endothelinantagonisten, Apolipoprotein AI-Antagonisten,Endothelin antagonists, apolipoprotein AI antagonists,
Cholesterol-Antagonisten,Cholesterol antagonists,
HMG CoA Reduktase-Inhibitoren,HMG CoA reductase inhibitors,
ACAT Inhibitoren,ACAT inhibitors,
ACE Inhibitoren, Angiotensinrezeptorantagonisten,ACE inhibitors, angiotensin receptor antagonists,
Tyrosinkinaseinhibitoren,Tyrosine kinase inhibitors,
Proteinkinase C-Inhibitoren, Kalzium-Kanal-Antagonisten, LDL-Rezeptor-Funktionsstimulantien, Antioxidantien und Freie Radikal-FängerProtein kinase C inhibitors, Calcium channel antagonists, LDL receptor function stimulants, antioxidants and free radical scavengers
zur Behandlung von Atherosklerose oderfor the treatment of atherosclerosis or
Gruppe 7 : cytostatische oder antineoplastische Verbindungen, Verbindungem die die Proliferation inhibieren, wie beispielsweise Kinaseinhibitoren und Heparin oder niedermolekulare Heparine oder weitere GAGsGroup 7: cytostatic or antineoplastic compounds, compounds which inhibit proliferation, such as kinase inhibitors and heparin or low molecular weight heparins or other GAGs
zur Behandlung von Krebs, vorzugsweise zur Inhibierung von Tumor- Wachstum oder -metastase, oderfor the treatment of cancer, preferably for the inhibition of tumor growth or metastasis, or
Gruppe 8:Group 8:
Verbindungen zur Anti-resorptiven Therapie,Connections to anti-resorptive therapy,
Verbindungen zur Hormon-Austausch-Therapie, wie beispielsweise Östrogen- oder Progesteron-Antagonisten,Compounds for hormone exchange therapy, such as, for example, estrogen or progesterone antagonists,
Rekombinantes humanes Wachstumshormon,Recombinant human growth hormone,
Bisphosphonate, wie beispielsweise AlendronateBisphosphonates such as alendronates
Verbindungen zur Calcitonintherapie,Connections to calcitonin therapy,
Calcitoninstimulantien, Kaizium-Kanal-Antagonisten,Calcitonin stimulants, calcium channel antagonists,
Knochenbildungsstimulantien, wie beispielsweise Wachstumsfaktora- gonisten,Bone formation stimulants, such as growth factor agonists,
Interleukin-6-Antagonisten undInterleukin-6 antagonists and
Src Tyrosinkinase-InhibitorenSrc tyrosine kinase inhibitors
zur Behandlung von Osteoporose oderfor the treatment of osteoporosis or
Gruppe 9 :Group 9:
TNF-Antagonisten, Antagonisten von VLA-4 oder VCAM-1,TNF antagonists, VLA-4 or VCAM-1 antagonists,
Antagonisten von LFA-1, Mac-1 oder ICAMS,Antagonists of LFA-1, Mac-1 or ICAMS,
Komplementinhibitoren,Complement inhibitors,
Immunosuppressiva,Immunosuppressants,
Interleukin-1-, -5- oder -8-Antagonisten und Dihydrofolatreduktase-InhibitorenInterleukin 1, -5 or 8 antagonists and dihydrofolate reductase inhibitors
zur Behandlung von rheumatoider Arthritis oderfor the treatment of rheumatoid arthritis or
Gruppe 10: Collagenase,Group 10: collagenase,
PDGF-Antagonisten und MMPs zur verbesserten Wundheilung.PDGF antagonists and MMPs for improved wound healing.
Unter einer Arzneimittelzubereitungen, enthaltend mindestens eine Verbindungen der Formel I, gebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, abhängig von der Indikation jeweils aus einer der vorstehenden Gruppen ausgewählt, wird eine kombinierte Verabreichung mindestens einer der Verbindungen der Formel 1 mit mindestens einer weiteren Verbindung jeweils ausgewählt aus einer der vorstehend beschriebenen Gruppen und gegebenenfalls ArzneimittelhilfStoffen, verstanden.From a pharmaceutical preparation containing at least one compound of the formula I, optionally pharmaceutical excipients and at least one further compound, depending on the indication selected from one of the above groups, a combined administration of at least one of the compounds of the formula 1 with at least one further compound is selected in each case from one of the groups described above and, where appropriate, pharmaceutical auxiliaries.
Die kombinierte Verabreichung kann durch ein Stoffgemisch, enthaltend mindestens eine Verbindungen der Formel I, gebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, abhängig von der Indikation jeweils aus einer der vorstehenden Gruppen ausgewählt, aber auch räumlich und/oder zeitlich getrennt erfolgen.The combined administration can be carried out by means of a mixture of substances containing at least one compound of the formula I, optionally pharmaceutical excipients and at least one further compound, depending on the indication, in each case selected from one of the above groups, but also spatially and / or chronologically separated.
Bei der räumlich und/oder zeitlich getrennten Verabreichung erfolgt die Verabreichung der Komponenten der Arzneimittelzubereitung, die Verbindungen der Formel 1 und die Verbindungen ausgewählt aus einer der vorstehend erwähnten Gruppen räumlich und/ oder zeitlich getrennt.In the case of spatially and / or chronologically separate administration, the components of the pharmaceutical preparation, the compounds of formula 1 and the compounds selected from one of the groups mentioned above are administered spatially and / or chronologically separately.
Zur Behandlung von Restenose nach Gefäßverletzung oder Stenting kann die Verabreichungen der Verbindungen der Formel I alleine oder in Kombination mit mindestens einer Verbindung ausgewählt aus der Gruppe 4 lokal auf die betroffenen Stellen erfolgen. Auch kann es vorteilhaft sein, die Stents mit diesen Verbindungen zu überziehen.For the treatment of restenosis after vascular injury or stenting, the compounds of the formula I can be administered alone or in combination with at least one compound selected from group 4 locally to the affected sites. It can also be advantageous to coat the stents with these compounds.
Zur Behandlung von Osteoporose kann es vorteilhaft sein, die Verabreichung der Verbindungen der Formel I in Kombination mit einer antiresorptiven oder Hormonaustausch-Therapie durchzuführen.For the treatment of osteoporosis, it may be advantageous to administer the compounds of the formula I in combination with an antiresorptive or hormone exchange therapy.
Die Erfindung betrifft demnach die Verwendung der vorstehend erwähnten Arzneimittelzubereitungen zur Herstellung von Arzneimittel zur Behandlung von Krankheiten.The invention accordingly relates to the use of the pharmaceutical preparations mentioned above for the production of pharmaceuticals for the treatment of diseases.
In einer bevorzugten Ausführungsform betrifft die Erfindung die Verwendung der vorstehend erwähnten kombinierten Arzneimittelzubereitungen zur Herstellung von Arzneimitteln zur Behandlung vonIn a preferred embodiment, the invention relates to the use of the aforementioned combined pharmaceutical preparations for the production of pharmaceuticals for the treatment of
Blutplättchen vermitteltem vaskulärem Verschluß oder Thrombose bei Verwendung von Verbindungen der Gruppe 1, Myokardinfarkt oder Schlaganfall bei Verwendung von Verbindungen der Gruppe 2,Platelet mediated vascular occlusion or thrombosis using group 1 compounds, Myocardial infarction or stroke when using group 2 compounds,
kongestivem Herzversagen bei Verwendung von Verbindungen der Gruppe 3,congestive heart failure when using group 3 compounds,
Restenose nach Gefäßverletzung bei Verwendung von Verbindungen der Gruppe 4,Restenosis after vascular injury when using group 4 compounds,
diabetischen Angiopathien bei Verwendung von Verbindungen der Gruppe 5,diabetic angiopathies when using group 5 compounds,
Atherosklerose bei Verwendung von Verbindungen der Gruppe 6,Atherosclerosis when using group 6 compounds,
Krebs bei Verwendung von Verbindungen der Gruppe 7,Cancer when using group 7 compounds,
Osteoporose bei Verwendung von Verbindungen der Gruppe 8,Osteoporosis when using group 8 compounds,
Rheumatoider Arthritis bei Verwendung von Verbindungen der Gruppe 9,Rheumatoid arthritis when using group 9 compounds,
Wundheilung bei Verwendung von Verbindungen der Gruppe 10.Wound healing when using group 10 compounds.
Die folgenden Beispiele erläutern die Erfindung, wobei die Auswahl dieser Beispiele nicht limitierend ist.The following examples illustrate the invention, the selection of these examples being not limiting.
I. Synthesebeispiele I .A VorstufenI. Synthesis Examples I .A Precursors
Darstellung der Bausteine LRepresentation of the blocks L
3- (4-Methylphenyl) -ß-alanin3- (4-methylphenyl) -ß-alanine
4-Methylbenzaldehyd (30 g, 0,25 mol) wurde in 500 ml Ethanol vorgelegt, Malonsäure (25,9 g, 0,25 mol) und Ammoniumacetat (28,8 g, 0,374 mol) zugegeben, und die Mischung für 8 h auf Rück- fluß erhitzt. Nach beendeter Umsetzung wurde auf 5°C abgekühlt, der entstandene Niederschlag abgesaugt, mit kaltem Ethanol und Diethylether nachgewaschen, und im Trockenschrank bei 40°C getrocknet . 19,9 g; ESI-MS [M+H+] = 180. Fmoc-3- (4-Methylphenyl ) -ß-alanin4-Methylbenzaldehyde (30 g, 0.25 mol) was placed in 500 ml of ethanol, malonic acid (25.9 g, 0.25 mol) and ammonium acetate (28.8 g, 0.374 mol) were added, and the mixture for 8 h heated to reflux. When the reaction was complete, the mixture was cooled to 5 ° C., the precipitate formed was suction filtered, washed with cold ethanol and diethyl ether and dried in a drying cabinet at 40 ° C. 19.9 g; ESI-MS [M + H + ] = 180. Fmoc-3- (4-methylphenyl) -ß-alanine
3- (4-Methylphenyl) -ß-alanin 1 (7 g, 39,6 mmol) wurden in einer Mischung aus 160 ml wäßriger 10 % Na2C03-Lösung und 50 ml THF ge- löst. Anschließend wurde Fmoc-Cl (10,31 g, 39,8 mmol) - gelöst in 40 ml THF - zugegeben, und über Nacht bei Raumtemperatur gerührt. Zur Aufarbeitung wurde die Reaktionsmischung mit konz. HCI auf pH 2 gestellt, und zweimal mit Diethylether extrahiert. Die vereinigten organischen Phasen wurden anschließend getrocknet (NaS0 ) , eingeengt, der verbliebene Rückstand aus Diethylether/ Cyclohexan kristallisiert und getrocknet. Auf diese Weise wurden 14 g eines weißen Feststoffs erhalten. ESI-MS [M+H+] = 4023- (4-Methylphenyl) -ß-alanine 1 (7 g, 39.6 mmol) were mixed in a mixture of 160 ml of aqueous 10% Na 2 CO 3 solution and 50 ml of THF. solves. Then Fmoc-Cl (10.31 g, 39.8 mmol) - dissolved in 40 ml THF - was added and the mixture was stirred overnight at room temperature. For working up, the reaction mixture was concentrated with. HCl adjusted to pH 2, and extracted twice with diethyl ether. The combined organic phases were then dried (NaSO 4), concentrated, the remaining residue was crystallized from diethyl ether / cyclohexane and dried. In this way 14 g of a white solid were obtained. ESI-MS [M + H + ] = 402
Darstellung von Bausteinen A-ERepresentation of blocks A-E
2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-carbonsäureethyl- ester 2-Amino-l, 3-thiazol-carbonsäureethylester (1,6 g, 9,82 mmol) und Benzylisocyanat (1,31 g, 9,83 mmol) wurden in 10 ml CH2C12 7 h lang auf Rückfluß erhitzt. Nach beendeter Umsetzung wurde die Mischung eingeengt. Chromatographie des erhaltenen Rückstands an Kieselgel (CH2Cl2/CH3OH 2 %) ergab 2,4 g der Verbindung.2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazole-4-carboxylic acid ethyl ester 2-amino-l, 3-thiazole-carboxylic acid ethyl ester (1.6 g, 9.82 mmol) and benzyl isocyanate (1, 31 g, 9.83 mmol) were refluxed in 10 ml CH 2 C1 2 for 7 hours. After the reaction was complete, the mixture was concentrated. Chromatography of the residue obtained on silica gel (CH 2 Cl 2 / CH 3 OH 2%) gave 2.4 g of the compound.
2-{ [ (Benzylamino)carbonyl] amino}-l, 3-thiazol-4-carbonsäure 2-{ [ (Benzylamino)carbonyl] amino}-l, 3-thiazol-4-carbonsäureethyl- ester (2,4 g, 7,86 mmol) wurde in 10 ml CH3OH und 1 ml H20 suspendiert, LiOH (0,18 g, 7,86 mmol) zugesetzt, und 18 h bei Raumtemperatur gerührt. Nach beendeter Reaktion wurden 20 ml H20 zugegeben, mit konz. HCI auf pH 1 gestellt, der entstandene Feststoff abgesaugt und getrocknet. 1,3 g; ESI-MS [M+H+] = 2782- {[(Benzylamino) carbonyl] amino} -l, 3-thiazole-4-carboxylic acid 2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazole-4-carboxylic acid ethyl ester (2.4 g, 7.86 mmol) was suspended in 10 ml of CH 3 OH and 1 ml of H 2 0, LiOH (0.18 g, 7.86 mmol) was added, and the mixture was stirred at room temperature for 18 h. After the reaction had ended, 20 ml of H 2 O were added, with conc. HCl adjusted to pH 1, the solid formed suction filtered and dried. 1.3 g; ESI-MS [M + H +] = 278
(2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-yl)-essigsäure- ethylester(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) ethyl acetate
Die Umsetzung erfolgte analog mit 2-Amino-l, 3-thiazol-4-yl-essig- säureethylester (1,25 g, 9,39 mmol). Nach Chromatographie wurden 2,8 g der Verbindung erhalten.The reaction was carried out analogously with 2-amino-1,3-thiazol-4-yl-acetic acid ethyl ester (1.25 g, 9.39 mmol). After chromatography, 2.8 g of the compound were obtained.
(2-{ [ (Benzylamino)carbonyl]amino}-1, 3-thiazol-4-yl) -essigsaure Die Umsetzung erfolgte analog aus (2-{ [ (Benzylamino)-carbonyl] - amino}-l,3-thiazol-4-yl)-essigsäureethylester (2,8 g, 8,77 mmol) und ergab 1,9 g der Verbindung als weißen Feststoff; ESI-MS [M+H+] = 292.(2- {[(Benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetic acid The reaction was carried out analogously from (2- {[(benzylamino) carbonyl] amino} -1, 3-thiazole -4-yl) ethyl acetate (2.8 g, 8.77 mmol) to give 1.9 g of the compound as a white solid; ESI-MS [M + H + ] = 292.
2-{ [ (Benzylamino)carbonyl]amino}-l,3-oxazol-5-carbonsäure2- {[(Benzylamino) carbonyl] amino} -l, 3-oxazole-5-carboxylic acid
a) Methylchloressigester (32,6 g, 0,30 mol) und Methylformiat (25,2 g, 0,42 mol) gelöst in Ether (300 mL) wurden unter Kühlung (0 bis 10°C) zu einer Lösung von Kaliumethanolat (29,9 g, 0,32 mol) in 80 ml Ethanol getropft. Die entstehende Suspension wurde 1,5 h bei 5°C und 12 h bei Raumtemperatur nachgerührt. Das entstandene Salz wurde abfiltriert und mit Diethylether gewaschen. Der Rückstand wurde in H20 gelöst, bei 4°C auf pH 3 mit HCI (10 N) angesäuert und mit Diethyl- ether extrahiert. Die vereinigten organischen Fraktionen wurden getrocknet, filtriert und zur Trockne einrotiert; 12,7 g.a) Methyl chloroacetic ester (32.6 g, 0.30 mol) and methyl formate (25.2 g, 0.42 mol) dissolved in ether (300 mL) were cooled (0 to 10 ° C) to a solution of potassium ethanolate ( 29.9 g, 0.32 mol) in 80 ml of ethanol. The emerging Suspension was stirred for 1.5 h at 5 ° C and 12 h at room temperature. The resulting salt was filtered off and washed with diethyl ether. The residue was dissolved in H 2 0, acidified to pH 3 with HCl (10 N) at 4 ° C. and extracted with diethyl ether. The combined organic fractions were dried, filtered and evaporated to dryness; 12.7 g.
b) Ethylformylchloressigester (10,0 g, 66,42 mmol) und Harnstoff (4,4 g, 73,97 mmol) wurden 60 ml H03,5 h auf Rückfluß erhitzt. Nach beendeter Reaktion wurde die Mischung filtriert und das Filtrat eingeengt. Chromatographie (MPLC, RP, Chroma- sil 100 C18, Gradient 1 bis 11 % Acetonitril) des erhaltenen Rückstands ergab 0,66 g der Verbindung.b) Ethyl formyl chloroacetic ester (10.0 g, 66.42 mmol) and urea (4.4 g, 73.97 mmol) were heated to reflux with 60 ml of H03.5 h. After the reaction was complete, the mixture was filtered and the filtrate was concentrated. Chromatography (MPLC, RP, Chromatos 100 C18, gradient 1 to 11% acetonitrile) of the residue obtained gave 0.66 g of the compound.
c) 2-Amino-l, 3-oxazol-5-carbonsäureethylester (0,3 g, 1,92 mmol) und Benzylisocyanat (0,26 g, 1,92 mmol) wurden in 15 ml Toluol 8 h lang auf Rückfluß erhitzt. Nach beendeter Umsetzung wurde die Mischung mit Wasser (15 ml) gewaschen, mit 5 % Citronensäure (2 x 15 m) extrahiert und mit H20 ausgeschüttelt. Die organische Phase wurde getrocknet und eingeengt. Eine Mischung (1,27 g) aus Benzylamin, Dibenzyl- harnstoff und gewünschtes Produkt (25 % Reinheit) fällt aus Ethylacetat aus und wurde ohne weitere Reinigung umgesetzt.c) Ethyl 2-amino-l, 3-oxazole-5-carboxylate (0.3 g, 1.92 mmol) and benzyl isocyanate (0.26 g, 1.92 mmol) were refluxed in 15 ml of toluene for 8 hours . After the reaction had ended, the mixture was washed with water (15 ml), extracted with 5% citric acid (2 × 15 m) and extracted with H 2 O. The organic phase was dried and concentrated. A mixture (1.27 g) of benzylamine, dibenzylurea and the desired product (25% purity) precipitates from ethyl acetate and was reacted without further purification.
d) 2-{ [ (Benzylamino) carbonyl] amino}-l, 3-oxazol-5-carbonsäure- ethylester (0,35 g, 25 % Reinheit) wurde in 20 ml CH3OH und 20 ml H20 suspendiert, NaOH (1 N, 2,56 mmol) zugesetzt, und 6 h bei 35°C gerührt. Nach beendeter Reaktion wurde ein- geengt, die Wasserphase mit HCI (2 N) auf pH 2 angesäuert und mit Ethylacetat erschöpfend extrahiert. Die vereinigte organische Phasen wurden getrocknet, filtriert und eingeengt, Ausrühren in Acetonitril ergab 136 mg der Verbindung; ESI-MS [M+H+] = 262,05.d) 2- {[(benzylamino) carbonyl] amino} -1, 3-oxazole-5-carboxylic acid ethyl ester (0.35 g, 25% purity) was suspended in 20 ml CH 3 OH and 20 ml H 2 0, NaOH (1N, 2.56 mmol) was added, and the mixture was stirred at 35 ° C. for 6 h. When the reaction was complete, the mixture was concentrated, the water phase was acidified to pH 2 with HCl (2 N) and extracted exhaustively with ethyl acetate. The combined organic phases were dried, filtered and concentrated, stirring in acetonitrile gave 136 mg of the compound; ESI-MS [M + H +] = 262.05.
2-{ [ (Benzylamino) carbonyl] amino}-!, 3-oxazol-4-carbonsäure2- {[(Benzylamino) carbonyl] amino} - !, 3-oxazole-4-carboxylic acid
a) Bromethylpyruvat (59,7 g, 0,306 mol) und Harnstoff (27,6 g, 0,46 mol) wurden in 220 ml Ethanol 24 h lang auf Rückfluß erhitzt. Die Mischung wurde eingedampft, der verbliebenea) Bromethylpyruvate (59.7 g, 0.306 mol) and urea (27.6 g, 0.46 mol) were heated to reflux in 220 ml of ethanol for 24 hours. The mixture was evaporated, the remaining one
Rückstand mit 20 ml H20 versetzt, mit In NaOH-Lösung ein pH von 10 eingestellt und mit CH2C12 extrahiert. Einengen der org. Phasen und Verrühren des Rückstands mit Diethylether ergab 12,3 g der freien Base,- ESI-MS [M+H+] = 157,05. Die Mutterlauge wurde wurde bei 10°C mit etherischer HCI versetzt. Auf diese Weise wurden noch 11,4 g des Esters als Hydrochlorid erhalten.20 ml of H 2 0 were added to the residue, the pH was adjusted to 10 with NaOH solution and the mixture was extracted with CH 2 C1 2 . Narrowing the org. Phasing and stirring the residue with diethyl ether gave 12.3 g of the free base, - ESI-MS [M + H +] = 157.05. The mother liquor was mixed with ethereal HCl at 10 ° C. In this way, 11.4 g of the ester were obtained as the hydrochloride.
b) 4 g 2-Amino-l, 3-oxazol-4-carbonsäureethylester wurden mit Benzylisocyanat (3,75 g; 0,13 mmol) und 3,3 g Diisopropyl- ethylamin in 60 ml Toluol 1 h lang auf Rückfluß erhitzt. Nach beendeter Reaktion wurde die Mischung eingedampft, der Rückstand in CH2C12 aufgenommen und mit In HCI- und ges . NaCl- Lösung gewaschen. Trocknen der org. Phase, Einengen und Verrühren des Rückstands in Methyl-tert .butylether ergaben 4,6 g weiße Festkörper; ESI-MS [M+H+] = 290,05.b) 4 g of 2-amino-l, 3-oxazole-4-carboxylic acid ethyl ester were refluxed with benzyl isocyanate (3.75 g; 0.13 mmol) and 3.3 g of diisopropylethylamine in 60 ml of toluene for 1 hour. After the reaction had ended, the mixture was evaporated, the residue was taken up in CH 2 C1 2 and washed with In HCl and sat. Washed NaCl solution. Drying the org. Phase, concentration and stirring of the residue in methyl tert-butyl ether gave 4.6 g of white solid; ESI-MS [M + H + ] = 290.05.
c) 4,3 g 2-{ [ (Benzylamino) carbonyl]amino}-l, 3-oxazol-4-carbon- säureethylester in 120 ml Dioxan/H20 2:1 wurden mit 1,4 g KOH versetzt und 2 h auf Rückfluß erhitzt. Einengen der Mischung und Ansäuern mit 2 n HCI ergab einen weißen Niederschlag, der abgesaugt, mit Aceton nachgewaschen und getrocknet wurde. 3,38 g; ESI-MS [M+H+] = 262,05.c) 4.3 g of ethyl 2- {[(benzylamino) carbonyl] amino} -l, 3-oxazole-4-carbonate in 120 ml of dioxane / H 2 0 2: 1 were mixed with 1.4 g of KOH and 2 h heated to reflux. Concentration of the mixture and acidification with 2N HCl gave a white precipitate which was filtered off with suction, washed with acetone and dried. 3.38 g; ESI-MS [M + H +] = 262.05.
4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol-2-carbonsäure4- {[(benzylamino) carbonyl] amino} -l-methyl-1H-pyrrole-2-carboxylic acid
4-Amino-l-methyl-pyrrol-2-methylcarboxylat (4 g, 26 mmol) wurden in 40 ml Toluol und 70 ml THF suspendiert und 1 eq Benzyliso- cyanat als Lösung in 10 ml THF zugegeben. Die Mischung wurde über Nacht gerührt und der entstandene Niederschlag abfiltriert. Die Mutterlauge wurde eingeengt, das verbliebene Öl mit Diethylether versetzt und der entstandene Niederschlag abfiltriert. Ver- einigung der Niederschläge ergab 5,16 g; ESI-MS: M+H+ = 288 7,18 g (25 mmol) des Methylesters wurden in 150 ml THF gelöst und 2 eq LiOH in Wasser gelöst zugegeben. Es wurde 3 h bei Raumtemp. gerührt. Dann wurde neutralisiert, eingeengt, mit HCI angesäuert und der weiße Niederschlag abgesaugt. Waschen mit H20 und Kristallisation aus ca. 100 ml Ethanol ergaben 3,90 g; ESI-MS: M+H+ = 274, 0.4-Amino-l-methyl-pyrrole-2-methylcarboxylate (4 g, 26 mmol) were suspended in 40 ml of toluene and 70 ml of THF and 1 eq of benzyl isocyanate was added as a solution in 10 ml of THF. The mixture was stirred overnight and the precipitate formed was filtered off. The mother liquor was concentrated, the remaining oil was mixed with diethyl ether and the precipitate formed was filtered off. Association of the precipitates yielded 5.16 g; ESI-MS: M + H + = 288 7.18 g (25 mmol) of the methyl ester were dissolved in 150 ml THF and 2 eq LiOH dissolved in water were added. It was 3 h at room temp. touched. The mixture was then neutralized, concentrated, acidified with HCl and the white precipitate was filtered off with suction. Washing with H 2 0 and crystallization from about 100 ml of ethanol gave 3.90 g; ESI-MS: M + H + = 274.0.
5-{ [ (Benzylamino) carbonyl] amino}thiophen-2-carbonsäure5- {[(Benzylamino) carbonyl] amino} thiophene-2-carboxylic acid
a) 85 ml Methanol wurden bei 0°C vorgelegt und dann 7,76 mla) 85 ml of methanol were placed at 0 ° C and then 7.76 ml
Thionylchlorid bei 0°C zugetropft. Zu dieser Mischung wurden 16,8 g (97 mmol) 2-Nitrothiophen-5-carbonsäure portionsweise zugegeben und danach 5 h bei Raumtemperatur gerührt. Es wurden noch 6 h bei 40°C gerührt. Nach dem Abkühlen wurde die Mischung mit Eiswasser versetzt, der Niederschlag abfiltriert, mit Wasser gewaschen und in Ethylacetat aufgenommen. Die Phasen wurden separiert, die organische Phase 4x mit Wasser gewaschen, mit Na2S04 getrocknet und eingeengt (16,45 g).Thionyl chloride was added dropwise at 0 ° C. 16.8 g (97 mmol) of 2-nitrothiophene-5-carboxylic acid were added in portions to this mixture and the mixture was then stirred at room temperature for 5 h. The mixture was stirred at 40 ° C for 6 h. After cooling, the mixture was mixed with ice water, the precipitate was filtered off, washed with water and taken up in ethyl acetate. The phases were separated, the organic phase Washed 4x with water, dried with Na 2 S04 and concentrated (16.45 g).
b) 9,2 g (49 mmol) 2-Nitrothiophen-5-carbonsäuremethylester wurden in 600 ml Eisessig gelöst, und bei 40°C portionsweise mit 27,45 g Eisenpulver (Merck, Fe durch Reduktion) versetzt. Nach mehreren Stunden wurde abgesaugt, der Feststoff mit Eisessig, Ethylacetat und Dichlormethan gewaschen. Die Filtrate wurden vereinigt, mit NaS0 getrocknet und eingeengt. Der ölige Rückstand wurde in Diethylether aufgenommen und das Hydrochlorid mit 6n isopropanolischer HCI ausgefällt. Absaugen und Trocknen ergaben 5,80 g.b) 9.2 g (49 mmol) of 2-nitrothiophene-5-carboxylic acid methyl ester were dissolved in 600 ml of glacial acetic acid, and 27.45 g of iron powder (Merck, Fe by reduction) were added in portions at 40 ° C. After several hours, the mixture was filtered off with suction, and the solid was washed with glacial acetic acid, ethyl acetate and dichloromethane. The filtrates were combined, dried with NaSO and concentrated. The oily residue was taken up in diethyl ether and the hydrochloride was precipitated with 6N isopropanolic HCl. Sucking off and drying gave 5.80 g.
c) 5,80 g (30 mmol) des Aminothiophens wurden in 50 ml Toluol mit 10,2 ml Diisopropylethylamin und 85 ml THF vorgelegt.c) 5.80 g (30 mmol) of the aminothiophene were placed in 50 ml of toluene with 10.2 ml of diisopropylethylamine and 85 ml of THF.
Nach Zugabe von 1 eq Benzylisocyanat wurde über Nacht gerührt, anschließend ca. 13 h unter Rückfluß gekocht, die schwarze Lösung eingeengt, in Ethylacetat aufgenommen und mit In HCI, Wasser und ges. NaHC03-Lösung extrahiert. Die wäßrigen Phasen wurden verworfen. Der entstehende Niederschlag wurde abfiltriert, die Mutterlauge mit NaS04 getrocknet und auf 20 ml eingeengt. Der entstandene Niederschlag wurde abfiltriert und mit kaltem Ethylacetat gewaschen. 6,70 g; ESI-MS: M+H+ = 291,0.After adding 1 eq of benzyl isocyanate, the mixture was stirred overnight, then refluxed for about 13 h, the black solution was concentrated, taken up in ethyl acetate and washed with 1N HCl, water and sat. NaHC0 3 solution extracted. The aqueous phases were discarded. The resulting precipitate was filtered off, the mother liquor was dried with NaSO 4 and concentrated to 20 ml. The resulting precipitate was filtered off and washed with cold ethyl acetate. 6.70 g; ESI-MS: M + H + = 291.0.
d) 6,6 g (22,8 mmol) des Methylesters wurden in 150 ml THF gelöst und 1,1 g LiOH in Wasser gelöst hinzugegeben. Nach 3 h wurde erneut 0,55 g LiOH hinzugegeben und die Mischung bei 60°C 16 h gerührt. Nach Einengen und Extraktion des Rück- Stands mit Ethylacetat wurde die wäßrige Phase wird mitd) 6.6 g (22.8 mmol) of the methyl ester were dissolved in 150 ml of THF and 1.1 g of LiOH dissolved in water were added. After 3 hours, 0.55 g of LiOH was again added and the mixture was stirred at 60 ° C. for 16 hours. After concentration and extraction of the residue with ethyl acetate, the aqueous phase was washed with
Aktivkohle entfärbt, mit HCI angesäuert und das ausfallende Produkt abfiltriert. Nach Trocknen verblieben 4,5 g; ESI-MS: M+H+ = 277,0.Activated carbon decolorized, acidified with HCI and the precipitated product filtered off. After drying, 4.5 g remained; ESI-MS: M + H + = 277.0.
5-{ [ (Benzylamino) carbonyl] amino}-4H-l, 2, 4-triazol-3-carbonsäure5- {[(Benzylamino) carbonyl] amino} -4H-1,2,4,4-triazole-3-carboxylic acid
a) 100 ml Methanol wurden bei 0°C mit 10.9 ml Thionylchlorid versetzt und dann bei Raumtemperatur 12,81 g (100 mmol) 1,2, 4-Triazol-5-carbonsäure hemihydrat versetzt. Es wurde 16 h bei Raumtemperatur gerührt, das Reaktionsgemisch eingeengt und mit 100 ml ges. NaHC03-Lösung versetzt. Der vorhandene voluminöse Niederschlag wurde abgesaugt, von Ethylacetat im Vakuum befreit und aus 200 ml Wasser umkristallisiert. 10,51 g; ESI-MS: M+H+ = 143,0. b) 10.35 g (72,9 mmol) des Aminotriazols wurden in 350 mla) 100 ml of methanol were mixed at 0 ° C with 10.9 ml of thionyl chloride and then added 12.81 g (100 mmol) of 1,2,4-triazole-5-carboxylic acid hemihydrate at room temperature. It was stirred for 16 h at room temperature, the reaction mixture was concentrated and saturated with 100 ml. NaHC0 3 solution added. The voluminous precipitate present was filtered off, freed from ethyl acetate in vacuo and recrystallized from 200 ml of water. 10.51 g; ESI-MS: M + H + = 143.0. b) 10.35 g (72.9 mmol) of the aminotriazole in 350 ml
Toluol, 16 ml Diisopropyl-ethylamin und 85 ml THF gelöst, 1,11 eq Benzylisocyanat hinzugegeben und die Mischung 5 h bei Rückfluß gerührt. Die Lösung wurde eingeengt, in Ethylacetat aufgenommen und die org. Phase mit 1 n Salzsäure, H20 (2x) , ges. NaHC03-Lösung und H20 (2x) extrahiert. Die org. Phase wurde mit Na2S04 getrocknet, eingeengt und der Rückstand mit Diethylether verrührt. 15,7 g; ESI-MS [M+H+] = 276,1.Toluene, 16 ml of diisopropylethylamine and 85 ml of THF dissolved, 1.11 eq of benzyl isocyanate added and the mixture stirred at reflux for 5 h. The solution was concentrated, taken up in ethyl acetate and the org. Phase with 1N hydrochloric acid, H 2 0 (2x), sat. NaHC0 3 solution and H 2 0 (2x) extracted. The org. Phase was dried with Na 2 S0 4 , concentrated and the residue was stirred with diethyl ether. 15.7 g; ESI-MS [M + H +] = 276.1.
c) 15,42 g (56,1 mmol) des Triazolcarbonsäuremethylesters wurden in 360 ml THF gelöst und dann 2,55 g LiOH in 250 ml Wasser hinzugegeben. Nach 4 h wurde eingeengt, mit Ethylacetat versetzt, mit HCI angesäuert, die org. Phase mit Wasser, ges. NaHC03-Lösung und Wasser extrahiert. Das ausfallende Produkt wurde abgesaugt und getrocknet. 1,50 g; ESI-MS [M+H+] = 262,0.c) 15.42 g (56.1 mmol) of the triazolecarboxylic acid methyl ester were dissolved in 360 ml of THF and then 2.55 g of LiOH in 250 ml of water were added. After 4 h, the mixture was concentrated, treated with ethyl acetate, acidified with HCl, the org. Phase with water, sat. NaHC0 3 solution and water extracted. The product which precipitated was filtered off and dried. 1.50 g; ESI-MS [M + H +] = 262.0.
4-{ [ (Benzylamino) carbonyl]amino}thiophen-2-carbonsäure4- {[(benzylamino) carbonyl] amino} thiophene-2-carboxylic acid
a) Zu 160 ml Methanol wurden bei 0°C 19,24 g Thionylchlorid getropft und anschließend portionsweise 25,45 g (147 mmol) 2-Nitrothiophen-4-carbonsäure zugesetzt. Es wurde 4,5 h bei 45°C nachgerührt. Nach dem Abkühlen wurde mit 160 ml Wasser versetzt und der entstandene Niederschlag abgesaugt. 26,75 g.a) 19.24 g of thionyl chloride were added dropwise to 160 ml of methanol at 0 ° C., and 25.45 g (147 mmol) of 2-nitrothiophene-4-carboxylic acid were then added in portions. The mixture was stirred at 45 ° C for 4.5 h. After cooling, 160 ml of water were added and the precipitate formed was suction filtered. 26.75 g.
b) 21,5 g (115 mmol) des Nitrothiophens wurden in 1,4 1 Eisessig vorgelegt, auf 40°C erwärmt und portionsweise mit 10 eq Eisen (Merck, durch Reduktion hergestellt) versetzt. Nach mehreren Stunden wurde der Feststoff abgesaugt, mit Eisessig, Ethyl- acetat und Dichlormethan gewaschen, die Mutterlauge mit der doppelten Menge Wasser versetzt, mit Dichlormethan 4x extrahiert und die vereinigten org. Phasen mit Na2S04 getrocknet und eingeengt. Der Rückstand wurde in Diethylether aufgenommen und mit 6 n isopropanolischer HCI in das Hydrochlorid überführt. Absaugen und Trocknen ergaben 13,3 g.b) 21.5 g (115 mmol) of the nitrothiophene were placed in 1.4 l of glacial acetic acid, warmed to 40 ° C. and 10 eq of iron (Merck, produced by reduction) were added in portions. After several hours, the solid was filtered off with suction, washed with glacial acetic acid, ethyl acetate and dichloromethane, twice the amount of water was added to the mother liquor, extracted 4 times with dichloromethane and the combined org. Phases dried with Na 2 S0 4 and concentrated. The residue was taken up in diethyl ether and converted into the hydrochloride using 6N isopropanolic HCl. Sucking off and drying gave 13.3 g.
!H-NMR (d6-DMS0) d (ppm) = 3,75 (s, 3H, OCH3) , 6,75, 7,70 (je s, 1H, Ar-H) ) ! H-NMR (d6-DMS0) d (ppm) = 3.75 (s, 3H, OCH 3 ), 6.75, 7.70 (each s, 1H, Ar-H))
c) 20,4 g (105,3 mmol) des Aminothiophens wurden in 530 ml Toluol, 85 ml THF und 27,2 g Diisopropylethylamin vorgelegt. Anschließend wurden 14,0 g Benzylisocyanat zugegeben und bei Raumtemperatur 16 h, dann 3 h bei Rückfluß gerührt. Die schwarze Lösung wurde eingeengt, in Ethylacetat aufgenommen, mit 1 n HCI, Wasser und ges. NaHC03-Lösung extrahiert. Die org. Phase wurde mit Na2S04 getrocknet, eingeengt und der Rückstand mit Diethylether verrührt; 21,0 g. d) 28 g (96,2 mmol) des Thiophenmethylesters wurden in 600 ml THF gelöst und 4,62 g LiOH in 350 ml Wasser hinzugegeben. Nach 3 h bei 60°C wurde das THF i. Vak. entfernt und der wäßrige Rückstand mit Ethylacetat 2x extrahiert. Die wäßrige Phase wurde mit Salzsäure angesäuert und das ausfallendec) 20.4 g (105.3 mmol) of the aminothiophene were placed in 530 ml of toluene, 85 ml of THF and 27.2 g of diisopropylethylamine. Then 14.0 g of benzyl isocyanate were added and the mixture was stirred at room temperature for 16 h, then at reflux for 3 h. The black solution was concentrated, taken up in ethyl acetate, with 1N HCl, water and sat. NaHC0 3 solution extracted. The org. Phase was dried with Na 2 S0 4 , concentrated and the residue was stirred with diethyl ether; 21.0 g. d) 28 g (96.2 mmol) of the thiophene methyl ester were dissolved in 600 ml of THF and 4.62 g of LiOH in 350 ml of water were added. After 3 h at 60 ° C the THF i. Vak. removed and the aqueous residue extracted twice with ethyl acetate. The aqueous phase was acidified with hydrochloric acid and the precipitated
Produkt abgesaugt. Zur Reinigung wurde in NaOH-Lösung aufgenommen, mit Aktivkohle versetzt und über Celite abgesaugt. Ansäuern mit HCI, Absaugen und Trocknen ergaben 20,0 g; ESI-MS: [M+H+]= 277, 0.Aspirated product. For cleaning, it was taken up in NaOH solution, mixed with activated carbon and suction filtered through Celite. Acidification with HCI, suction and drying gave 20.0 g; ESI-MS: [M + H + ] = 277.0.
5-{ [ (Benzylamino) carbonyl]amino}-2-furancarbonsäure5- {[(Benzylamino) carbonyl] amino} -2-furan carboxylic acid
a) 10 g (70,86 mmol) 5-Aminofuran-2-carbonsäuremethylester werden in 200 ml THF gelöst, 10,07 g Hünig-Base zugegeben und dann 18,87 g (141,7 mmol) Benzylisocyanat zugetropft. Die Lösung wird 6 h bei 30°C gerührt, dann i. Hochvak. eingeengt und der Rückstand in Ethylacetat aufgenommen. Es wird mit 1 n HCI, Wasser und ges. NaCl Lösung gewaschen. Die organ. Phase wird getrocknet und eingeengt. Der Rückstand wird mit wenig Methanol versetzt, kurz aufgekocht und in einem Eisbad gekühlt. Der Feststoff wird abgesaugt, mit wenig kaltem Methanol gewaschen und getrocknet (14,0 g) . ESI-MS [M+H+] = 408,15a) 10 g (70.86 mmol) of 5-aminofuran-2-carboxylic acid methyl ester are dissolved in 200 ml of THF, 10.07 g of Hünig base are added and then 18.87 g (141.7 mmol) of benzyl isocyanate are added dropwise. The solution is stirred at 30 ° C. for 6 h, then i. High vacuum concentrated and the residue taken up in ethyl acetate. It is mixed with 1N HCl, water and sat. Washed NaCl solution. The organ. Phase is dried and concentrated. A little methanol is added to the residue, boiled briefly and cooled in an ice bath. The solid is filtered off, washed with a little cold methanol and dried (14.0 g). ESI-MS [M + H + ] = 408.15
b) 10,50 g (25,77 mmol) 5-{Bis [ (benzylamino) carbonyl] amino}-2- furancarbonsäuremethylester werden in 100 ml THF suspendiert und 18,5 g (773 mmol) LiOH in 100 ml Wasser zugegeben. Die Suspension rührt 20 h bei Raumtemp. Zur Mischung wird Ethylacetat und Wasser gegeben, die wäßrige Phase abgetrennt und noch zweimal mit Ethylacetat gewaschen. Anschließend wird mit 10 % HCI pH 1 eingestellt, 1 der ausfallende Feststoff abfiltriert, mit Wasser gewaschen und getrocknet (5,92 g) . ESI-MS [M+H+] = 261,05b) 10.50 g (25.77 mmol) of methyl 5- {bis [(benzylamino) carbonyl] amino} -2-furancarboxylic acid are suspended in 100 ml of THF and 18.5 g (773 mmol) of LiOH in 100 ml of water are added. The suspension is stirred at room temperature for 20 h. Ethyl acetate and water are added to the mixture, the aqueous phase is separated off and washed twice more with ethyl acetate. The mixture is then adjusted to pH 1 with 10% HCl, 1 the precipitated solid is filtered off, washed with water and dried (5.92 g). ESI-MS [M + H + ] = 261.05
Beispiele I.BExamples I.B
Synthese der Verbindungen der Formel I (A-E-G-L)Synthesis of the compounds of the formula I (A-E-G-L)
Beispiel 1example 1
N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl]-amino}acetyl) -3- (4-methylphenyl) -ß-alanin (1)N - ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] -amino} acetyl) -3- (4-methylphenyl) -ß-alanine (1 )
1.1 H- [3- (4-Methylphenyl) -ß-alanin] -Trityl-Harz1.1 H- [3- (4-methylphenyl) -ß-alanine] trityl resin
3,0 g Cl-Trityl-Harz wurden in Dichlormethan suspendiert, Diisopropylethylamin (1,64 ml, 9 mmol) und 3-(4-Methyl- phenyl ) -ß-alanin (1,45 g, 3,6 mmol) zugegeben und über Nacht bei RT geschüttelt. Anschließend wurden erneut 1,5 ml Diisopropylethylamin und 9 ml Methanol zugegeben und nochmals 30 min geschüttelt. Das Harz wurde abgesaugt und nacheinander mit Dimethylformamid, CHC12, CH3OH und CH2C1 gewaschen. Zur Abspaltung der Fmoc-Schutzgruppe wurde das Harz in Piperidin/ CH2C12 1:1 20 min bei RT geschüttelt, abgesaugt, mit CHC1 5x gewaschen. Die Schutzgruppenspaltung wurde insgesamt 2x durchgeführt. Anschließend wurde das Harz erneut gewaschen mit Dimethylformamid, CH2C12, CH3OH und CH2C12 und über Nacht bei RT im Trockenschrank getrocknet. Die Auswaage betrug 3,44 g (Beladung: 0,896 g/mmol) .3.0 g of Cl-trityl resin were suspended in dichloromethane, diisopropylethylamine (1.64 ml, 9 mmol) and 3- (4-methylphenyl) -ß-alanine (1.45 g, 3.6 mmol) were added and shaken at RT overnight. Then again 1.5 ml of diisopropylethylamine and 9 ml of methanol were added and again Shaken for 30 minutes. The resin was filtered off and washed successively with dimethylformamide, CHC1 2 , CH 3 OH and CH 2 C1. To remove the Fmoc protective group, the resin was shaken in piperidine / CH 2 C1 2 1: 1 for 20 min at RT, filtered off with suction, washed 5 times with CHC1. The protection groups were split twice in total. The resin was then washed again with dimethylformamide, CH 2 C1 2 , CH 3 OH and CH 2 C1 2 and dried overnight at RT in a drying cabinet. The weight was 3.44 g (loading: 0.896 g / mmol).
1.2 H-Gly- [3- (4-Methylphenyl ) -ß-alanin] -Trityl-Harz1.2 H-Gly- [3- (4-methylphenyl) -ß-alanine] trityl resin
H- [3- (4-Methylphenyl) -ß-alanin] -Trityl-Harz (111,6 mg,H- [3- (4-methylphenyl) -ß-alanine] trityl resin (111.6 mg,
0,1 mmol) wurde in Dimethylformamid suspendiert, Fmoc-Gly-OH0.1 mmol) was suspended in dimethylformamide, Fmoc-Gly-OH
(59,5 mg, 0,2 mmol), Diisopropylethylamin (34,4 ml, 0,2 mmol) und TBTU (64,4 mg, 0,2 mmol) zugesetzt und 48 h lang bei(59.5 mg, 0.2 mmol), diisopropylethylamine (34.4 ml, 0.2 mmol) and TBTU (64.4 mg, 0.2 mmol) were added and added for 48 h
Raumtemperatur geschüttelt. Das Harz wurde dann abgesaugt und nacheinander mit Dimethylformamid, CH2C12, CH3OH und CH2C12 gewaschen. Zur Abspaltung der Fmoc-Schutzgruppe wurde das Harz in Piperidin/CHC12 1:1 20 min bei RT geschüttelt, ab- gesaugt, mit CH2C12 5x gewaschen. Die Schutzgruppenspaltung wurde insgesamt 2x durchgeführt. Anschließend wurde das Harz erneut gewaschen mit Dimethylformamid, CH2C12, CH3OH und CH2C12 und über Nacht bei RT im Trockenschrank getrocknet.Shaken at room temperature. The resin was then suctioned off and washed successively with dimethylformamide, CH 2 C1 2 , CH 3 OH and CH 2 C1 2 . To remove the Fmoc protective group, the resin was shaken in piperidine / CHC1 2 1: 1 for 20 min at RT, filtered off with suction, washed with CH 2 C1 2 5x. The protection groups were split twice in total. The resin was then washed again with dimethylformamide, CH 2 C1 2 , CH 3 OH and CH 2 C1 2 and dried overnight at RT in a drying cabinet.
1.3 N- ({[ (2-{[ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) - carbonyl] amino}acetyl) -3- (4-methylphenyl)-ß-alanin (1) 0,03 mmol H-Gly- [3- (4-Methylphenyl) -ß-alanin] -Trityl-Harz wurden in DMF suspendiert, 2-{[ (Benzylamino) carbonyl] amino}- 1, 3-thiazol-4-carbonsäure (17,5 mg, 0,06 mmol), Diiso- propylethylamin (10,32 ml, 0,06 mmol) und TBTU (19,32 mg, 0,06 mmol) zugesetzt und über Nacht bei Raumtemperatur geschüttelt. Das Harz wurde dann abgesaugt und nacheinander mit Dimethylformamid, CH2C12, CH3OH und CH2C12 gewaschen. Anschließend wurde zur Spaltung vom Harz mit 1,5 ml einer Mischung aus Trifluor-ethanol/Essigsäure/CH2Cl2 1:1:3 versetzt und erneut 1 h bei Raumtemperatur geschüttelt. Eindampfen der Spaltlösung, Versetzen des Rückstandes mit 2 ml Essigsäure und Lyophilisieren ergab 5 mg des gewünschten Produktes, ESI-MS [M+H+] = 496.1.3 N- ({[(2 - {[(Benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) carbonyl] amino} acetyl) -3- (4-methylphenyl) -ß-alanine (1 ) 0.03 mmol H-Gly- [3- (4-methylphenyl) -ß-alanine] trityl resin was suspended in DMF, 2 - {[(benzylamino) carbonyl] amino} - 1, 3-thiazole-4 Carboxylic acid (17.5 mg, 0.06 mmol), diisopropylethylamine (10.32 ml, 0.06 mmol) and TBTU (19.32 mg, 0.06 mmol) were added and shaken overnight at room temperature. The resin was then suctioned off and washed successively with dimethylformamide, CH 2 C1 2 , CH 3 OH and CH 2 C1 2 . Subsequently, 1.5 ml of a mixture of trifluoroethanol / acetic acid / CH 2 Cl 2 1: 1: 3 was added to cleave the resin and the mixture was shaken again at room temperature for 1 h. Evaporation of the cleavage solution, addition of the residue with 2 ml of acetic acid and lyophilization gave 5 mg of the desired product, ESI-MS [M + H + ] = 496.
Beispiel 2Example 2
N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l,3-thiazol-4-yl)acetyl]- amino}acetyl ) -3- (4-methylphenyl) -ß-alanin (2 )N - ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) acetyl] - amino} acetyl) -3- (4-methylphenyl) -ß-alanine (2)
0,03 mmol H-Gly- [3- (4-Methylphenyl) -ß-alanin] -Trityl-Harz wurden in DMF suspendiert, (2-{ [ (Benzylamino)carbonyl]amino}-l,3- thiazol-4-yl) -essigsaure (17,5 mg, 0,06 mmol), Diisopropyl-ethyl- amin (10,32 ml, 0,06 mmol) und TBTU (19,32 mg, 0,06 mmol) zugesetzt und über Nacht bei Raumtemperatur geschüttelt. Das Harz wurde dann abgesaugt und nacheinander mit Dimethylformamid, CH2C12, CH3OH und CH2C12 gewaschen. Anschließend wurde zur Spaltung vom Harz mit 1,5 ml einer Mischung aus Trifluorethanol/ Essigsäure/CH2C12 1:1:3 versetzt und erneut 1 h bei Raumtemperatur geschüttelt. Eindampfen der Spaltlösung, Versetzen des Rückstandes mit 2 ml Essigsäure und Lyophilisieren ergab 8 mg des gewünschten Produktes, ESI-MS [M+H+] = 510. Die Spaltlösung wurde dann zur Trockenen eingedampft, der Rückstand in Essigsäure aufgenommen und lyophilisiert.0.03 mmol H-Gly- [3- (4-methylphenyl) -ß-alanine] trityl resin was suspended in DMF, (2- {[(benzylamino) carbonyl] amino} -l, 3-thiazole-4 -yl) -acetic acid (17.5 mg, 0.06 mmol), diisopropyl-ethyl- amine (10.32 ml, 0.06 mmol) and TBTU (19.32 mg, 0.06 mmol) were added and shaken overnight at room temperature. The resin was then suctioned off and washed successively with dimethylformamide, CH 2 C1 2 , CH 3 OH and CH 2 C1 2 . Then 1.5 ml of a mixture of trifluoroethanol / acetic acid / CH 2 C1 2 1: 1: 3 was added to cleave the resin and the mixture was shaken again at room temperature for 1 h. Evaporation of the cleavage solution, addition of the residue with 2 ml of acetic acid and lyophilization gave 8 mg of the desired product, ESI-MS [M + H +] = 510. The cleavage solution was then evaporated to dryness, the residue was taken up in acetic acid and lyophilized.
Beispiel 3Example 3
N- ({ [ (2-{ t (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}acetyl) -3- (3-pyridinyl) -ß-alanin (3)N- ({[(2- {t (benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] amino} acetyl) -3- (3-pyridinyl) -ß-alanine (3)
3.1 H- [3- (3-Pyridinyl ) -ß-alanin] -Trityl-Harz Durchführung analog zur Herstellung von H- [3-(4-Methyl- phenyl ) -ß-alanin] -Trityl-Harz . H-Gly- [3- (3-Pyridinyl) -ß-alanin] -Trityl-Harz3.1 H- [3- (3-pyridinyl) -ß-alanine] trityl resin Carried out analogously to the preparation of H- [3- (4-methylphenyl) -ß-alanine] trityl resin. H-Gly- [3- (3-pyridinyl) -ß-alanine] trityl resin
H- [3- (3-Pyridinyl) -ß-alanin] -Trityl-Harz (106,4 mg, 0,1 mmol) wurde in Dimethylformamid suspendiert, Fmoc-Gly-OH (59,5 mg, 0,2 mmol), Diisopropylethylamin (34,4 ml, 0,2 mmol) und TBTU (64,4 mg, 0,2 mmol) zugesetzt und 48 h lang bei Raum- temperatur geschüttelt. Das Harz wurde abgesaugt und nacheinander mit Dimethylformamid, CHC12, CH3OH und CH2C1 gewaschen. Zur Abspaltung der Fmoc-Schutzgruppe wurde das Harz in Piperidin/CH2C1 1:1 20 min bei RT geschüttelt, abgesaugt, mit CH2C12 5x gewaschen. Die Schutzgruppenspaltung wurde ins- gesamt 2x durchgeführt. Anschließend wurde das Harz erneut gewaschen mit Dimethylformamid, CHC12, CH30H und CH2C12 und über Nacht bei RT im Trockenschrank getrocknet.H- [3- (3-pyridinyl) -ß-alanine] trityl resin (106.4 mg, 0.1 mmol) was suspended in dimethylformamide, Fmoc-Gly-OH (59.5 mg, 0.2 mmol ), Diisopropylethylamine (34.4 ml, 0.2 mmol) and TBTU (64.4 mg, 0.2 mmol) were added and shaken at room temperature for 48 h. The resin was filtered off and washed successively with dimethylformamide, CHC1 2 , CH 3 OH and CH 2 C1. To remove the Fmoc protective group, the resin was shaken in piperidine / CH 2 C1 1: 1 for 20 min at RT, filtered off with suction, washed with CH 2 C1 2 5 times. The protection groups were split twice in total. The resin was then washed again with dimethylformamide, CHC1 2 , CH 3 0H and CH 2 C1 2 and dried overnight at RT in a drying cabinet.
3.2 N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl) - carbonyl] amino}acetyl) -3- (3-pyridinyl) -ß-alanin (3)3.2 N - ({[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) carbonyl] amino} acetyl) -3- (3-pyridinyl) -ß-alanine (3rd )
0,03 mmol H-Gly- [3- (3-Pyridinyl)-b-alanin] -Trityl-Harz wurden in DMF suspendiert, 2-{ [ (Benzylamino) carbonyl] amino}-1,3- thiazol-4-carbonsäure 4 (17,5 mg, 0,06 mmol), Diisopropylethylamin (10,32 ml, 0,06 mmol) und TBTU (19,32 mg, 0,06 mmol) zugesetzt und über Nacht bei Raumtemperatur geschüttelt. Das Harz wurde dann abgesaugt und nacheinander mit Dimethylformamid, CHC12, CH3OH und CHC12 gewaschen. Anschließend wurde zur Spaltung vom Harz mit 1,5 ml einer Mischung aus Trifluor-ethanol/Essigsäure/CH2Cl2 1:1:3 versetzt und erneut 1 h bei Raumtemperatur geschüttelt. Eindampfen der Spaltlösung, Versetzen des Rückstandes mit 2 ml Essigsäure und Lyophilisieren ergab 8 mg des gewünschten Produktes, ESI-MS [M+H+] = 483.0.03 mmol H-Gly- [3- (3-pyridinyl) -b-alanine] trityl resin were suspended in DMF, 2- {[(benzylamino) carbonyl] amino} -1,3-thiazole-4- carboxylic acid 4 (17.5 mg, 0.06 mmol), diisopropylethylamine (10.32 ml, 0.06 mmol) and TBTU (19.32 mg, 0.06 mmol) were added and shaken overnight at room temperature. The resin was then suctioned off and washed successively with dimethylformamide, CHC1 2 , CH 3 OH and CHC1 2 . Subsequently, 1.5 ml of a mixture of trifluoroethanol / acetic acid / CH 2 Cl 2 1: 1: 3 was added to cleave the resin and the mixture was shaken again at room temperature for 1 h. Evaporation of the cleavage solution, adding 2 ml of acetic acid to the residue and lyophilization gave 8 mg of the desired product, ESI-MS [M + H +] = 483.
Beispiel 4 5 N- ( { [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl)acetyl] - amino}acetyl)-3- (3-pyridinyl) -ß-alanin (4)Example 4 5 N- ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) acetyl] - amino} acetyl) -3- (3-pyridinyl) -ß-alanine (4)
0,03 mmol H-Gly- [3- (3-Pyridinyl) -ß-alanin] -Trityl-Harz wurden in DMF suspendiert, (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-0.03 mmol H-Gly- [3- (3-pyridinyl) -ß-alanine] trityl resin was suspended in DMF, (2- {[(benzylamino) carbonyl] amino} -l, 3-thiazole-
10 4-yl) -essigsaure (17,5 mg, 0,06 mmol), Diiso-propyl-ethylamin (10,32 ml, 0,06 mmol) und TBTU (19,32 mg, 0,06 mmol) zugesetzt und über Nacht bei Raumtemperatur geschüttelt. Das Harz wurde dann abgesaugt und nacheinander mit Dimethylformamid, CH2C12, CH3OH und CH2C1 gewaschen. Anschließend wurde zur Spaltung vom10 4-yl) acetic acid (17.5 mg, 0.06 mmol), diisopropylethylamine (10.32 ml, 0.06 mmol) and TBTU (19.32 mg, 0.06 mmol) were added and shaken overnight at room temperature. The resin was then suctioned off and washed successively with dimethylformamide, CH 2 C1 2 , CH 3 OH and CH 2 C1. Subsequently, the split from
15 Harz mit 1,5 ml einer Mischung aus Trifluor-ethanol/Essigsäure/ CH2C12 1:1:3 versetzt und erneut 1 h bei Raumtemperatur geschüttelt. Eindampfen der Spaltlösung, Versetzen des Rückstandes mit 2 ml Essigsäure und Lyophilisieren ergab 10 mg des gewünschten Produktes, ESI-MS [M+H+] = 497.15 resin with 1.5 ml of a mixture of trifluoroethanol / acetic acid / CH 2 C1 2 1: 1: 3 and shaken again at room temperature for 1 h. Evaporation of the cleavage solution, addition of the residue with 2 ml of acetic acid and lyophilization gave 10 mg of the desired product, ESI-MS [M + H + ] = 497.
2020th
Analog wurden hergestellt:The following were produced analogously:
N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] -amino}acetyl)-3- (3, 5-dichlorophenyl) -ß-alanin (5)N - ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) -carbonyl] -amino} acetyl) -3- (3, 5-dichlorophenyl) -ß-alanine (5)
25 21 mg; ESI-MS [M+H+] = 550.25 21 mg; ESI-MS [M + H +] = 550.
N- ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}acetyl) -3- (2-naphthyl) -ß-alanin (6) 15 mg; ESI-MS [M+H+] = 532. 30N- ({[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] amino} acetyl) -3- (2-naphthyl) -ß-alanine (6) 15 mg; ESI-MS [M + H +] = 532. 30
N- ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}acety1) -3- [1, 1'-biphenyl] -4-y1-ß-alanin (7) 22 mg; ESI-MS [M+H+] = 560.N- ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) carbonyl] amino} acety1) -3- [1, 1'-biphenyl] -4-y1 -ß-alanine (7) 22 mg; ESI-MS [M + H +] = 560.
35 N-({ [ (2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-yl) - carbonyl] amino}acetyl) -3- (2 , 3-dimethoxyphenyl) -ß-alanin (8)35 N - ({[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) carbonyl] amino} acetyl) -3- (2, 3-dimethoxyphenyl) -ß-alanine (8th)
18 mg; ESI-MS [M+H+] = 542.18 mg; ESI-MS [M + H +] = 542.
N- ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - 40 carbonyl] amino}acetyl) -3- ( 1-naphthyl) -ß-alanin (9)N- ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - 40 carbonyl] amino} acetyl) -3- (1-naphthyl) -ß-alanine (9 )
19 mg; ESI-MS [M+H+] = 532.19 mg; ESI-MS [M + H +] = 532.
N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl)acetyl] amino}acetyl)-3-(3, 5-dichlorophenyl) -ß-alanin (10) 45 42 mg; ESI-MS [M+H+] = 565. N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl) acetyl] amino}acetyl)-3- (2-naphthyl) -ß-alanin (11) 44 mg; ESI-MS [M+H+] = 546.N - ({[(2- {[(Benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetyl] amino} acetyl) -3- (3, 5-dichlorophenyl) -ß-alanine (10 ) 45 42 mg; ESI-MS [M + H +] = 565. N - ({[(2- {[(Benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetyl] amino} acetyl) -3- (2-naphthyl) -ß-alanine (11) 44 mg; ESI-MS [M + H +] = 546.
5 N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl) acetyl] amino}acetyl)-3- [1,1 '-biphenyl]-4-yl-alanin (12) 7 mg; ESI-MS [M+H+] = 572.5 N - ({[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetyl] amino} acetyl) -3- [1,1'-biphenyl] -4-yl -alanine (12) 7 mg; ESI-MS [M + H +] = 572.
N- ({ t (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl)acetyl] ■ 10 amino}acetyl ) -3- (2 , 3-dimethoxyphenyl) -ß-alanin (13) 30 mg; ESI-MS [M+H+] = 556.N- ({t (2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) acetyl] ■ 10 amino} acetyl) -3- (2, 3-dimethoxyphenyl) -ß-alanine (13) 30 mg; ESI-MS [M + H +] = 556.
N- ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl)acetyl] ■ amino}acetyl) -3- (1-naphthyl) -ß-alanin (14) 15 37 mg; ESI-MS [M+H+] = 546.N- ({[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetyl] ■ amino} acetyl) -3- (1-naphthyl) -ß-alanine (14) 15 37 mg; ESI-MS [M + H +] = 546.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) - acetyl]amino}-propanoyl)-3- (3, 5-dichlorophenyl) -ß-alanin (15) 24 mg; ESI-MS [M+H+] = 579. 20N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) acetyl] amino} propanoyl) -3- (3, 5- dichlorophenyl) -ß-alanine (15) 24 mg; ESI-MS [M + H +] = 579.20
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) - acetyl] amino}-propanoy1) -3- (3-pyridiny1) -ß-alanin (16) 7,1 mg; ESI-MS [M+H+] = 511.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) -acetyl] amino} -propanoy1) -3- (3-pyridiny1) -ß-alanine (16) 7.1 mg; ESI-MS [M + H +] = 511.
25 N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl) - acetyl] mino}-propanoyl) -3-(2-naphthyl) -ß-alanin (17) 17 mg; ESI-MS [M+H+] = 560.25 N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetyl] mino} propanoyl) -3- (2-naphthyl ) -ß-alanine (17) 17 mg; ESI-MS [M + H +] = 560.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) - 30 acetyl] amino}-propanoyl) -3-[1, l'-biphenyl] -4-yl-ß-alanin (18) 20 mg; ESI-MS [M+H+] = 586.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) - 30 acetyl] amino} -propanoyl) -3- [1,1 '-biphenyl] -4-yl-β-alanine (18) 20 mg; ESI-MS [M + H +] = 586.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-yl)- acetyl] amino}-propanoyl) -3- (2 , 3-dimethoxyphenyl) -ß-alanin (19) 35 16 mg; ESI-MS [M+H+] = 570.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - acetyl] amino} -propanoyl) -3- (2, 3- dimethoxyphenyl) -ß-alanine (19) 35 16 mg; ESI-MS [M + H +] = 570.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-yl)- acetyl]amino}-propanoyl) -3- (1-naphthyl)-ß-alanin (20) 16 mg; ESI-MS [M+H+] = 560.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - acetyl] amino} -propanoyl) -3- (1-naphthyl) -ß-alanine (20) 16 mg; ESI-MS [M + H +] = 560.
4040
N-( (2S)-2-{ [ (2-{ [(Benzylamino) carbonyl]amino}-l, 3-thiazol-4-yl)' acetyl] mino}-propanoyl) -3- (4-methylphenyl) -ß-alanin (21) 19 mg; ESI-MS [M+H+] = 524.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) 'acetyl] mino} -propanoyl) -3- (4-methylphenyl) -ß-alanine (21) 19 mg; ESI-MS [M + H +] = 524.
45 N-( (2S)-2-{ [ (2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-yl)- carbonyl]amino}-propanoyl)-3-(3, 5-dichlorophenyl) -ß-alanin (22) 18,5 mg; ESI-MS [M+H+] = 565.45 N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] amino} -propanoyl) -3- (3, 5- dichlorophenyl) -ß-alanine (22) 18.5 mg; ESI-MS [M + H +] = 565.
5 N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}-propanoyl) -3- (3-pyridinyl) -ß-alanin (23 ) 4,8 mg; ESI-MS [M+H+] = 497.5 N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) carbonyl] amino} -propanoyl) -3- (3-pyridinyl ) -ß-alanine (23) 4.8 mg; ESI-MS [M + H +] = 497.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l,3-thiazol-4-yl )- 10 carbonyl] amino}-propanoyl) -3- (2-naphthyl) -ß-alanin (24) 18,4 mg; ESI-MS [M+H+] = 546.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - 10 carbonyl] amino} -propanoyl) -3- (2-naphthyl ) -ß-alanine (24) 18.4 mg; ESI-MS [M + H +] = 546.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}-propanoyl) -3- [1, l'-biphenyl] -4-yl-ß-alanin (25) 15 16 mg; ESI-MS [M+H+] = 572.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] amino} -propanoyl) -3- [1, l ' -biphenyl] -4-yl-β-alanine (25) 15 16 mg; ESI-MS [M + H +] = 572.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl]amino}-l, 3-thiazol-4-yl) - carbonyl ] amino}-propanoyl) -3- (2 , 3-dimethoxypheny1) -ß-alanin (26) 15 mg; ESI-MS [M+H+] = 556. 20N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] amino} -propanoyl) -3- (2, 3- dimethoxypheny1) -ß-alanine (26) 15 mg; ESI-MS [M + H +] = 556.20
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}-propanoyl) -3- ( 1-naphthyl ) -ß-alanin (27) 13 mg; ESI-MS [M+H+] = 546.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] amino} -propanoyl) -3- (1-naphthyl) -ß-alanine (27) 13 mg; ESI-MS [M + H +] = 546.
25 N-( (2S)-2-{ [ (2-{ [(Benzylamino) carbonyl] amino}-l,3-thiazol-4-yl )- carbonyl] amino}-propanoyl) -3- (4-methylphenyl) -ß-alanin (28) 18 mg; ESI-MS [M+H+] = 510.25 N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) -carbonyl] amino} -propanoyl) -3- (4-methylphenyl ) -ß-alanine (28) 18 mg; ESI-MS [M + H +] = 510.
N-( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl]amino}-l, 3-thiazol-4-yl) - 0 acetyl] amino}-propanoyl) -3-(4-methylphenyl) -ß-alanin (29) 17,2mg; ESI-MS [M+H+] = 510.N- ((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - 0 acetyl] amino} -propanoyl) -3- (4-methylphenyl ) -ß-alanine (29) 17.2 mg; ESI-MS [M + H +] = 510.
(2S)-3-[ ( (2S)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol- 4-yl ) -acetyl] amino}-propanoyl) amino] -2-{ [ (benzyloxy) carbonyl] - 5 amino}propansäure (30)(2S) -3- [((2S) -2- {[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) -acetyl] amino} -propanoyl) amino] - 2- {[(benzyloxy) carbonyl] -5 amino} propanoic acid (30)
11,1 mg; ESI-MS [M+H+] = 583.11.1 mg; ESI-MS [M + H +] = 583.
(2S)-3-[ ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) - acetyl] -amino}acetyl)amino] -2-{ [ (benzyloxy) carbonyl] amino}propan- 0 säure (31)(2S) -3- [({[(2- {[(benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) acetyl] amino} acetyl) amino] -2- {[(benzyloxy ) carbonyl] amino} propanoic acid (31)
14,9 mg; ESI-MS [M+H+] = 569.14.9 mg; ESI-MS [M + H +] = 569.
(2S)-3-[ ( (2S)-2-{ [ (2-{ [(Benzylamino) carbonyl] amino}-1, 3-thiazol- 4-yl)carbonyl]-amino}propanoyl)amino]-2-{ [ (benzyloxy) carbonyl] - 5 amino}propansäure (32)(2S) -3- [((2S) -2- {[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) carbonyl] amino} propanoyl) amino] -2 - {[(benzyloxy) carbonyl] - 5 amino} propanoic acid (32)
6,5 mg; ESI-MS [M+H+] = 569. (2S)-3-[ ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l,3-thiazol-4-yl)- carbonyl] -amino}acetyl) amino] -2-{ [ (benzyloxy) carbonyl] amino}- propansäure (33) 5,9 mg; ESI-MS [M+H+] = 555. 56.5 mg; ESI-MS [M + H +] = 569. (2S) -3- [({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) - carbonyl] -amino} acetyl) amino] -2- {[(benzyloxy ) carbonyl] amino} - propanoic acid (33) 5.9 mg; ESI-MS [M + H +] = 555.5
N-{ [ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) acetyl]- (methy1) amino] acetyl }-3- (3-pyridinyl ) -ß-alanin (34) 15 mg; [M+H+] = 512.N- {[[(2- {[(Benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) acetyl] - (methy1) amino] acetyl} -3- (3-pyridinyl) -ß-alanine (34) 15 mg; [M + H +] = 512.
10 N-{ [ [ (2-{ [ (Benzylamino) carbonyl] amino}-l,3-thiazol-4-yl) acetyl] - (methyl) amino] acetyl}-3- (3 , 5-dichlorophenyl) -ß-alanin (35) 18 mg; [M+H+] = 579.10 N- {[[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) acetyl] - (methyl) amino] acetyl} -3- (3, 5-dichlorophenyl) - β-alanine (35) 18 mg; [M + H +] = 579.
(2R)-3-({ [ [(2-{ [(Benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl)- 15 acetyl]- (methyl) amino] acetyl}amino) -2-{ [ (benzyloxy) carbonyl] - amino}propansäure (36) 14 mg; [M+H+] = 583.(2R) -3 - ({[[(2- {[(Benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) - 15 acetyl] - (methyl) amino] acetyl} amino) -2- {[(benzyloxy) carbonyl] - amino} propanoic acid (36) 14 mg; [M + H +] = 583.
(2R)-3-({[(3-{[ (Benzylamino) carbonyl] aminoJbenzoyl) amino] acetyl}- 20 amino) -2-{ [ (benzyloxy) carbonyl] amino}propansäure (37) 10 mg; [M+H+] = 548.(2R) -3 - ({[(3 - {[(Benzylamino) carbonyl] aminoJbenzoyl) amino] acetyl} - 20 amino) -2- {[(benzyloxy) carbonyl] amino} propanoic acid (37) 10 mg; [M + H +] = 548.
(2R)-3-( { (2S)-2-[ (3-{ [ (Benzylamino) carbonyl] amino}benzoyl) amino] - propanoyl}amino) -2-{ [ (benzyloxy) carbonyl] amino}propansäure (38) 25 4 mg; [M+H+] = 562.(2R) -3- ({(2S) -2- [(3- {[(Benzylamino) carbonyl] amino} benzoyl) amino] - propanoyl} amino) -2- {[(benzyloxy) carbonyl] amino} propanoic acid ( 38) 25 4 mg; [M + H +] = 562.
N-{ [ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol-4-yl) - carbonyl]- (methyl) amino] acetyl}-3- (3, 5-dichlorophenyl) -ß- alanin (39) 30 16 mg; [M+H+] = 564.N- {[[(2- {[(benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) - carbonyl] - (methyl) amino] acetyl} -3- (3,5-dichlorophenyl) - β-alanine (39) 30 16 mg; [M + H +] = 564.
N-{ [ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] - (methyl) amino] acetyl}-3- (3-pyridinyl ) -ß-alanin (40 ) 18 mg; [M+H+] = 497.N- {[[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) carbonyl] - (methyl) amino] acetyl} -3- (3-pyridinyl) -ß- alanine (40) 18 mg; [M + H +] = 497.
3535
(2R)-3-({ [ [(2-{ [ (benzylamino) carbonyl] amino}-1, 3-thiazol-4-yl) - carbonyl]- (methyl) amino] acetyl}amino) -2-{ [ (benzyloxy) carbonyl] - amino}propansäure (41) 15 mg; [M+H+] = 569.(2R) -3 - ({[[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) - carbonyl] - (methyl) amino] acetyl} amino) -2- { [(benzyloxy) carbonyl] - amino} propanoic acid (41) 15 mg; [M + H +] = 569.
4040
N-( (2R)-2-{ [ (2-{ [(Benzylamino) carbonyl]amino}-1, 3-thiazol-4-yl) acetyl] amino}propanoyl ) -3- (3-pyridinyl) -ß-alanin (42 ) 18 mg; ESI-MS [M+H+] = 511.N- ((2R) -2- {[(2- {[(benzylamino) carbonyl] amino} -1, 3-thiazol-4-yl) acetyl] amino} propanoyl) -3- (3-pyridinyl) -ß -alanine (42) 18 mg; ESI-MS [M + H +] = 511.
5 N-( (2R)-2-{ [ (2-{ [ (Benzylamino)carbonyl]amino}-l,3-thiazol-4-yl) acetyl] amino}propanoyl)-3- (3 , 5-dichlorophenyl) -ß-alanin (43 ) 20 mg; ESI-MS [M+H+] = 579.5 N- ((2R) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) acetyl] amino} propanoyl) -3- (3, 5-dichlorophenyl) -ß-alanine (43) 20 mg; ESI-MS [M + H +] = 579.
5 N- ( (2R)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) ■ carbonyl] amino}propanoyl ) -3- (3 , 5-dichlorophenyl) -ß-alanin (44)5 N- ((2R) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) ■ carbonyl] amino} propanoyl) -3- (3, 5- dichlorophenyl) -ß-alanine (44)
16 mg; ESI-MS [M+H+] = 565.16 mg; ESI-MS [M + H +] = 565.
N- ( (2R)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) ■ 10 carbonyl]amino}propanoyl)-3-(3-pyridinyl)-ß-alanin (45) 10 mg; ESI-MS [M+H+] = 497.N- ((2R) -2- {[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) ■ 10 carbonyl] amino} propanoyl) -3- (3-pyridinyl) -ß-alanine (45) 10 mg; ESI-MS [M + H +] = 497.
(2S)-3-[ ( (2R)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-!, 3-thiazol- 4-yl) -carbonyl] aminoJpropanoyl)amino] -2-{ [ (benzyloxy) carbonyl] - 15 amino}propansäure (46)(2S) -3- [((2R) -2- {[(2- {[(Benzylamino) carbonyl] amino} - !, 3-thiazol-4-yl) carbonyl] aminoJpropanoyl) amino] -2- { [(benzyloxy) carbonyl] - 15 amino} propanoic acid (46)
12 mg; ESI-MS [M+H+] = 569.12 mg; ESI-MS [M + H +] = 569.
(2S)-3-[ ( (2R)-2-{ [ (2-{ [ (Benzylamino) carbonyl] amino}-1,3-thiazol- 4-yl ) acetyl] amino}propanoyl) amino] -2-{ [ (benzyloxy) carbonyl] - 20 amino}propansäure (47)(2S) -3- [((2R) -2- {[(2- {[(Benzylamino) carbonyl] amino} -1,3-thiazol-4-yl) acetyl] amino} propanoyl) amino] -2- {[(benzyloxy) carbonyl] - 20 amino} propanoic acid (47)
17 mg; ESI-MS [M+H+] = 583.17 mg; ESI-MS [M + H +] = 583.
N-{ [ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] (methyl)amino]acetyl}-3-cyclohexyl-ß-alanin (48) 25 12 mg; ESI-MS [M+H+] = 502.N- {[[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) carbonyl] (methyl) amino] acetyl} -3-cyclohexyl-ß-alanine (48) 25 12 mg; ESI-MS [M + H +] = 502.
N- ( { [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-4-yl) - carbonyl] amino}acetyl) -3-cyclohexyl-ß-alanin (49) 10 mg; ESI-MS [M+H+] = 488. 30N- ({[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-4-yl) carbonyl] amino} acetyl) -3-cyclohexyl-β-alanine (49) 10 mg; ESI-MS [M + H + ] = 488. 30
N-( { [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-thiazol-5-yl) - carbonyl] amino}acetyl) -3-pyridin-3-yl-beta-alanin (50) ; ESI-MS [M+H+] = 483.N- ({[(2- {[(benzylamino) carbonyl] amino} -l, 3-thiazol-5-yl) - carbonyl] amino} acetyl) -3-pyridin-3-yl-beta-alanine (50) ; ESI-MS [M + H + ] = 483.
35 N-({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-oxazol-4-yl) - carbonyl] amino}acetyl) -3-pyridin-3-yl-beta-alanin (51) ; ESI-MS [M+H+] = 467.35 N - ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-oxazol-4-yl) - carbonyl] amino} acetyl) -3-pyridin-3-yl-beta-alanine (51 ); ESI-MS [M + H + ] = 467.
0 N-({ [ (2-{ [ (Benzylamino) carbonyl]amino}-l,3-thiazol-5-yl)- carbonyl] amino}acetyl) -3- (2 , 5-dimethoxyphenyl) -beta-alanin (52); ESI-MS [M+H+] = 542. 5 N- ( { [ (2- { [ (Benzylamino) carbonyl ] amino }-l , 3-oxazol-4-yl ) - carbonyl] amino} acetyl ) -3- (2-naphthyl ) -beta-alanin ( 53 ) ; ESI-MS [M+H+] = 516.0 N - ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-thiazol-5-yl) -carbonyl] amino} acetyl) -3- (2,5-dimethoxyphenyl) -beta-alanine (52); ESI-MS [M + H + ] = 542.5 N- ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-oxazol-4-yl) - carbonyl] amino} acetyl) -3- (2-naphthyl) -beta-alanine (53) ; ESI-MS [M + H + ] = 516.
N- ( { [ (2-{ [ (Benzylamino) carbonyl]amino}-l, 3-oxazol-4-yl) - carbonyl] amino}acetyl) -3- (4-methylphenyl) -beta-alanin (54) ; ESI-MS [M+H+] = 480.N- ({[(2- {[(benzylamino) carbonyl] amino} -l, 3-oxazol-4-yl) - carbonyl] amino} acetyl) -3- (4-methylphenyl) beta-alanine (54) ; ESI-MS [M + H + ] = 480.
(2S)-3- [ ({ [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-oxazol- 4-yl) carbonyl]amino}acetyl)amino] -2-{ [ (benzyloxy) carbonyl] - amino}propansäure (55); ESI-MS [M+H+] = 539.(2S) -3- [({[(2- {[(benzylamino) carbonyl] amino} -l, 3-oxazol-4-yl) carbonyl] amino} acetyl) amino] -2- {[(benzyloxy) carbonyl ] - amino} propanoic acid (55); ESI-MS [M + H + ] = 539.
3-{l- [ ( { [ (4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH- pyrrol-2-yl ) carbonyl] amino}acetyl)amino] -2-carboxyethyl}- pyridinium acetat (56) ;3- {l- [({[(4- {[(Benzylamino) carbonyl] amino} -1-methyl-1H-pyrrol-2-yl) carbonyl] amino} acetyl) amino] -2-carboxyethyl} pyridinium acetate (56);
ESI-MS [M+H+] = 479.ESI-MS [M + H + ] = 479.
N-({ [ (4-{ [ (Benzylamino)carbonyl]amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] amino}acetyl) -3-(2-naphthyl) -beta-alanin (57) ;N - ({[(4- {[(Benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] amino} acetyl) -3- (2-naphthyl) -beta-alanine (57 );
ESI-MS [M+H+] = 528.ESI-MS [M + H + ] = 528.
(2S)-3- [ ({ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH- pyrrol-2-yl) carbonyl] amino}acetyl) amino] -2-{ [ (benzyloxy) - carbonyl] amino}propansäure (58); ESI-MS [M+H+] = 551.(2S) -3- [({[(4- {[(Benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] amino} acetyl) amino] -2- {[(benzyloxy ) - carbonyl] amino} propanoic acid (58); ESI-MS [M + H + ] = 551.
N-( { [ (4-{ [ (Benzylamino) carbonyl]amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] amino}acetyl) -3- [1, 1 '-bipheny1] -4-yl-beta- alanin (59);N- ({[(4- {[(Benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] amino} acetyl) -3- [1, 1 '-bipheny1] -4- yl-beta-alanine (59);
ESI-MS [M+H+] = 554.ESI-MS [M + H +] = 554.
N-({ [(4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH-pyrrol- 2-yl) carbonyl] amino}acetyl) -3- (4-methylphenyl)-beta- alanin (60) ;N - ({[(4- {[(Benzylamino) carbonyl] amino} -1-methyl-1H-pyrrol-2-yl) carbonyl] amino} acetyl) -3- (4-methylphenyl) beta-alanine (60 );
ESI-MS [M+H+] = 492.ESI-MS [M + H + ] = 492.
N- ( { [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol-N- ({[(4- {[(benzylamino) carbonyl] amino} -l-methyl-lH-pyrrole-
2-yl) carbonyl] amino}acetyl) -3-cyclohexyl-beta-alanin (61);2-yl) carbonyl] amino} acetyl) -3-cyclohexyl-beta-alanine (61);
ESI-MS [M+H+] = 484. N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] (methyl)amino] acetyl}-3-cyclohexyl-beta- alanin ( 62 ) ; ESI-MS [M+H+] = 498.ESI-MS [M + H + ] = 484. N- {[[(4- {[(benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] (methyl) amino] acetyl} -3-cyclohexyl-beta-alanine (62) ; ESI-MS [M + H + ] = 498.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] (methyl)amino] acetyl}-3- (3 , 4-dimethoxyphenyl ) - beta-alanin ( 63 ) ; ESI-MS [M+H+] = 552.N- {[[(4- {[(benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] (methyl) amino] acetyl} -3- (3, 4-dimethoxyphenyl) - beta-alanine (63); ESI-MS [M + H +] = 552.
N-(3-{ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] amino}propanoyl)-3-pyridin-3-yl-beta-alanin (64) ; ESI-MS [M+H+] = 493.N- (3- {[(4- {[(Benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] amino} propanoyl) -3-pyridin-3-yl-beta-alanine (64); ESI-MS [M + H + ] = 493.
N-(3-{ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] amino}propanoyl) -3- (2 , 5-dimethoxypheny1 ) -beta- alanin (65) ;N- (3- {[(4- {[(Benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] amino} propanoyl) -3- (2, 5-dimethoxypheny1) -beta - alanine (65);
ESI-MS [M+H+] = 552.ESI-MS [M + H +] = 552.
N-( (2R)-2-{ [(4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH- pyrrol-2-yl ) carbonyl] amino}propanoyl) -3- (4-tert-butylphenyl ) - beta-alanin (66); ESI-MS [M+H+] = 548.N- ((2R) -2- {[(4- {[(benzylamino) carbonyl] amino} -1-methyl-lH-pyrrol-2-yl) carbonyl] amino} propanoyl) -3- (4-tert- butylphenyl) beta-alanine (66); ESI-MS [M + H + ] = 548.
N-( (2R)-2-{ [(4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH- pyrrol-2-yl) carbonyl] amino}propanoyl) -3- (3, 4-dimethoxyphenyl) - beta-alanin (67); ESI-MS [M+H+] = 552.N- ((2R) -2- {[(4- {[(benzylamino) carbonyl] amino} -1-methyl-lH-pyrrol-2-yl) carbonyl] amino} propanoyl) -3- (3, 4- dimethoxyphenyl) - beta-alanine (67); ESI-MS [M + H + ] = 552.
(2S)-3- [ ({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) - carbonyl] amino}acetyl) amino] -2-{ [ (benzyloxy) carbonyl] amino}- propansäure (68); ESI-MS [M+H+] = 554.(2S) -3- [({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) - carbonyl] amino} acetyl) amino] -2- {[(benzyloxy) carbonyl] amino} - propanoic acid (68); ESI-MS [M + H + ] = 554.
N-({ [ (4-{ [ (Benzylamino) carbonyl]amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] amino}acetyl) -3- (3, 5-dichlorophenyl)-beta- alanin (69) ; ESI-MS [M+H+] = 546. N-({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl) -3-pyridin-3-yl-beta-alanin (70) ; ESI-MS [M+H+] = 482.N - ({[(4- {[(Benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] amino} acetyl) -3- (3, 5-dichlorophenyl) beta-alanine (69); ESI-MS [M + H + ] = 546. N - ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3-pyridin-3-yl-beta-alanine (70); ESI-MS [M + H + ] = 482.
N-({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl)-3-(3, 5-dichlorophenyl) -beta-alanin (71) ;N - ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3- (3,5-dichlorophenyl) beta-alanine (71);
ESI-MS [M+H+] = 549.ESI-MS [M + H + ] = 549.
N- ( { [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl) -3- (4-methylphenyl) -beta-alanin (72) ; ESI-MS [M+H+] = 495.N- ({[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3- (4-methylphenyl) beta-alanine (72); ESI-MS [M + H + ] = 495.
(2S)-3- [ ( { [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) - carbonyl] amino}acetyl ) amino] -2- [ (phenylsulfonyl ) amino]propansäure (73 ) ; ESI-MS [M+H+] = 560.(2S) -3- [({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} acetyl) amino] -2- [(phenylsulfonyl) amino] propanoic acid (73) ; ESI-MS [M + H + ] = 560.
N-({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl) -3- (4-tert-butylphenyl)-beta-alanin (74) ; ESI-MS [M+H+] = 537.N - ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3- (4-tert-butylphenyl) beta-alanine (74); ESI-MS [M + H +] = 537.
4-[({ [(5-{ [ (Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino}acetyl) amino] -3-{ [ (benzyloxy) carbonyl] amino}butansäure (75) ; ESI-MS [M+H+] = 568.4 - [({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) amino] -3- {[(benzyloxy) carbonyl] amino} butanoic acid (75); ESI-MS [M + H +] = 568.
N-( { [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl) -3-cyclohexyl-beta-alanin (76) ; ESI-MS [M+H+] = 487.N- ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3-cyclohexyl-beta-alanine (76); ESI-MS [M + H + ] = 487.
N-{ [ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - (methyl) amino] acetyl}-3-[l, l'-biphenyl] -4-yl-beta-alanin (77) ; ESI-MS [M+H+] = 571.N- {[[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - (methyl) amino] acetyl} -3- [l, l'-biphenyl] -4-yl-beta -alanine (77); ESI-MS [M + H + ] = 571.
N-{ [[ (5-{ [ (Benzylamino) carbonyl]amino}thien-2-yl) carbonyl] -N- {[[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] -
(methyl ) amino] acetyl}-3- (2 , 5-dimethoxyphenyl) -beta-alanin (78); ESI-MS [M+H+] = 555. N-{ [ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - (methyl) amino] acetyl} -3-(4-methylphenyl) -beta-alanin (79) ; ESI-MS [M+H+] = 509.(methyl) amino] acetyl} -3- (2,5-dimethoxyphenyl) beta-alanine (78); ESI-MS [M + H + ] = 555. N- {[[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - (methyl) amino] acetyl} -3- (4-methylphenyl) beta-alanine (79); ESI-MS [M + H + ] = 509.
(2S)-3-({ [ [ (5-{ [ (Benzylamino) carbonyl]amino}thien-2-yl) - carbonyl] (methyl) amino] acetyl}amino) -2-{ [ (benzyloxy) - carbonyl] amino}propansäure (80) ;(2S) -3 - ({[[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] (methyl) amino] acetyl} amino) -2- {[(benzyloxy) carbonyl ] amino} propanoic acid (80);
ESI-MS [M+H+] = 568.ESI-MS [M + H + ] = 568.
N-{ [ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - (methyl) amino] cetyl}-3-cyclohexyl-beta-alanin (81) ; ESI-MS [M+H+] = 501.N- {[[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - (methyl) amino] cetyl} -3-cyclohexyl-beta-alanine (81); ESI-MS [M + H + ] = 501.
N-{ [[(5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] -N- {[[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] -
(methyl)amino] acetyl}-3-(3, 4-dimethoxyphenyl) -beta-alanin (82) ; ESI-MS [M+H+] = 555.(methyl) amino] acetyl} -3- (3,4-dimethoxyphenyl) beta-alanine (82); ESI-MS [M + H + ] = 555.
4-( { [ [ (5-{ [ (Benzylamino)carbonyl] amino}thien-2-yl) carbonyl] -4- ({[[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] -
(methyl) amino] acetyl}amino) -3-{ [ (benzyloxy) carbonyl] amino} - butansäure ( 83 ) ,-(methyl) amino] acetyl} amino) -3- {[(benzyloxy) carbonyl] amino} - butanoic acid (83), -
ESI-MS [M+H+] = 582.ESI-MS [M + H +] = 582.
N-(3-{ [ (5-{ [ (Benzy1amino) carbonyl]amino}thien-2-yl) carbonyl] - amino}propanoyl)-3-pyridin-3-yl-beta-alanin (84) ; ESI-MS [M+H+] = 496.N- (3- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3-pyridin-3-yl-beta-alanine (84); ESI-MS [M + H + ] = 496.
N-(3-{ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] amino}propanoyl) -3- (2, 5-dimethoxyphenyl) -beta-alanin (85) ; ESI-MS [M+H+] = 555.N- (3- {[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3- (2,5-dimethoxyphenyl) beta-alanine (85); ESI-MS [M + H + ] = 555.
(2S)-3-[ (3-{ [ (5-{ [ (Benzylamino) carbonyl]amino}thien-2-yl) - carbonyl] amino}propanoyl) amino] -2-{ [ (benzyloxy) carbonyl] - amino}propansäure (86); ESI-MS [M+H+] = 568.(2S) -3- [(3- {[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) - carbonyl] amino} propanoyl) amino] -2- {[(benzyloxy) carbonyl] - amino} propanoic acid (86); ESI-MS [M + H + ] = 568.
N-(3-{ [ (5-{ [ (Benzylamino) carbonyl]amino}thien-2-yl) carbonyl] ■ amino}propanoyl)-3-cyclohexyl-beta-alanin (87) ; ESI-MS [M+H+] = 501. (2S)-3- [ (3-{ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) - carbony1] amino}propanoyl) amino] - - [ (phenylsulfonyl) amino] - propansäure (88);N- (3- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] ■ amino} propanoyl) -3-cyclohexyl-beta-alanine (87); ESI-MS [M + H + ] = 501. (2S) -3- [(3- {[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) - carbony1] amino} propanoyl) amino] - - [(phenylsulfonyl) amino] - propanoic acid ( 88);
5 ESI-MS [M+H+] = 574. 5 ESI-MS [M + H + ] = 574.
N-(3-{ [(5-{ [ (Benzylamino)carbonyl]amino}thien-2-yl) carbonyl] - amino}propanoyl) -3- (4-tert-butylphenyl) -beta-alanin (89); .N- (3- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3- (4-tert-butylphenyl) beta-alanine (89); .
ESI-MS [M+H+] = 551. 10ESI-MS [M + H + ] = 551.10
N-(3-{ [(5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}propanoyl)-3- (3 , 4-dimethoxyphenyl ) -beta-alanin (90) ; ESI-MS [M+H+] = 555.N- (3- {[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} propanoyl) -3- (3,4-dimethoxyphenyl) beta-alanine (90); ESI-MS [M + H + ] = 555.
1515
N-(3-{ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}propanoyl) -3- (3 , 4-dimethoxyphenyl) -beta-alanin (91) ; ESI-MS [M+H+] = 582.N- (3- {[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} propanoyl) -3- (3,4-dimethoxyphenyl) beta-alanine (91); ESI-MS [M + H + ] = 582.
20 N-( (2S)-2-{ [(5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) - carbonyl] amino}propanoyl) -3- (4-tert-butylphenyl)-beta- alanin ( 92 ) ; 20 N- ((2S) -2- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) - carbonyl] amino} propanoyl) -3- (4-tert-butylphenyl) -beta- alanine (92);
ESI-MS [M+H+] = 551.ESI-MS [M + H + ] = 551.
2525
N-( (2S)-2-{ [ (5-{ [ (Benzylamino) carbonyl] amino} thien-2-yl)- carbonyl] amino}propanoyl) -3- (3 , 4-dimethoxyphenyl) -beta- alanin ( 93 ) ;N- ((2S) -2- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3- (3, 4-dimethoxyphenyl) beta-alanine (93);
30 ESI-MS [M+H+] = 555.30 ESI-MS [M + H + ] = 555.
N-({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl)-3-(2, 5-dimethoxyphenyl) -beta-alanin (94) ;N - ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3- (2,5-dimethoxyphenyl) beta-alanine (94);
ESI-MS [M+H+] = 541. 35ESI-MS [M + H + ] = 541. 35
N-({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}acetyl) -3- (1-naphthyl ) -beta-alanin (95) ; ESI-MS [M+H+] = 531.N - ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3- (1-naphthyl) beta-alanine (95); ESI-MS [M + H + ] = 531.
4040
N-( { [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol-N- ({[(4- {[(benzylamino) carbonyl] amino} -l-methyl-lH-pyrrole-
2-yl) carbonyl] amino}acetyl) -3- (3 , 4-dimethoxyphenyl) -beta- alanin (96); a ESI-MS [M+H+] = 538. 5 N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH-pyrrol- 2-yl) carbonyl] (methyl ) amino] acetyl }-3- (3, 5-dichlorophenyl)- beta-alanin (97); ESI-MS [M+H+] = 560.2-yl) carbonyl] amino} acetyl) -3- (3,4-dimethoxyphenyl) beta-alanine (96); a ESI-MS [M + H + ] = 538. 5 N- {[[(4- {[(benzylamino) carbonyl] amino} -1-methyl-1H-pyrrol-2-yl) carbonyl] (methyl) amino] acetyl} -3- (3, 5-dichlorophenyl) - beta-alanine (97); ESI-MS [M + H +] = 560.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol- 2-y1 ) carbonyl ] (methyl ) amino] acetyl } -3-pyridin-3-y1-beta- alanin (98) ;N- {[[(4- {[(benzylamino) carbonyl] amino} -l-methyl-1H-pyrrole-2-y1) carbonyl] (methyl) amino] acetyl} -3-pyridin-3-y1-beta alanine (98);
ESI-MS [M+H+] = 493.ESI-MS [M + H + ] = 493.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH-pyrrol-N- {[[(4- {[(benzylamino) carbonyl] amino} -1-methyl-lH-pyrrole-
2-yl) carbonyl] (methyl ) amino] acetyl}-3- (2-naphthyl ) -beta- alanin (99) ;2-yl) carbonyl] (methyl) amino] acetyl} -3- (2-naphthyl) beta-alanine (99);
ESI-MS [M+H+] = 542.ESI-MS [M + H + ] = 542.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH-pyrrol-N- {[[(4- {[(benzylamino) carbonyl] amino} -1-methyl-lH-pyrrole-
2-yl) carbonyl] (methyl) amino] acetyl} -3- [1, l'-biphenyl] -4-yl- beta-alanin (100);2-yl) carbonyl] (methyl) amino] acetyl} -3- [1, l'-biphenyl] -4-yl-beta-alanine (100);
ESI-MS [M+H+] = 568.ESI-MS [M + H + ] = 568.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH-pyrrol- 2-yl) carbonyl] (methyl) amino] acetyl} -3- (2, 5-dimethoxyphenyl ) - beta-alanin (101); ESI-MS [M+H+] = 552.N- {[[(4- {[(benzylamino) carbonyl] amino} -1-methyl-1H-pyrrol-2-yl) carbonyl] (methyl) amino] acetyl} -3- (2, 5-dimethoxyphenyl) - beta-alanine (101); ESI-MS [M + H + ] = 552.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol- 2-yl) carbonyl] (methyl )amino] acetyl}-3- ( 1-naphthyl ) -beta- alanin (102) ; ESI-MS [M+H+] = 542.N- {[[(4- {[(benzylamino) carbonyl] amino} -l-methyl-1H-pyrrol-2-yl) carbonyl] (methyl) amino] acetyl} -3- (1-naphthyl) -beta- alanine (102); ESI-MS [M + H + ] = 542.
N-{ [ [ (4-{ [ (Benzylamino) carbonyl] amino}-l-methyl-lH-pyrrol-N- {[[(4- {[(benzylamino) carbonyl] amino} -l-methyl-lH-pyrrole-
2-yl ) carbonyl] (methyl)ammo]acetyl}-3- (4-methylphenyl) -beta- alanin (103); ESI-MS [M+H+] = 506.2-yl) carbonyl] (methyl) ammo] acetyl} -3- (4-methylphenyl) beta-alanine (103); ESI-MS [M + H + ] = 506.
(2S)-3-({ [[(4-{ [ (Benzylamino) carbonyl] amino}-1-methyl-lH- pyrrol-2-yl) carbonyl] (methyl) amino] acetyl}amino) -2-{ [ (benzyloxy) carbonyl] amino}propansäure (104) ; ESI-MS [M+H+] = 56,5. N-({ [ (5-{ [ (Benzylamino)carbonyl]amino}thien-2-yl)carbonyl]- amino}acetyl)-3-(3, 4-dimethoxyphenyl) -beta-alanin (105) ;(2S) -3 - ({[[(4- {[(Benzylamino) carbonyl] amino} -1-methyl-1H-pyrrol-2-yl) carbonyl] (methyl) amino] acetyl} amino) -2- { [(benzyloxy) carbonyl] amino} propanoic acid (104); ESI-MS [M + H + ] = 56.5. N - ({[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} acetyl) -3- (3,4-dimethoxyphenyl) beta-alanine (105);
ESI-MS [M+H+] = 541.ESI-MS [M + H + ] = 541.
N-{ [[(5-{ [ (Benzylamino) carbonyl]amino}thien-2-yl) carbonyl] -N- {[[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] -
(methyl) amino] acetyl}-3-pyridin-3-yl-beta-alanin (106) ; ESI-MS [M+H+] = 496.(methyl) amino] acetyl} -3-pyridin-3-yl-beta-alanine (106); ESI-MS [M + H + ] = 496.
N_(3_{ [ (5_{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}propanoyl ) -3- (1-naphthyl) -beta-alanin (107) ; ESI-MS [M+H+] = 545.N_ (3_ {[(5_ {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] - amino} propanoyl) -3- (1-naphthyl) beta-alanine (107); ESI-MS [M + H + ] = 545.
N-(3-{ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-2-yl) carbonyl] - amino}propanoyl) -3- (4-methylphenyl) -beta-alanin (108) ; ESI-MS [M+H+] = 509.N- (3- {[(5- {[(Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3- (4-methylphenyl) beta-alanine (108); ESI-MS [M + H + ] = 509.
N-({ [ (5-{ [ (Benzylamino) carbonyl] amino}thien-3-yl) carbonyl] - ammo}acetyl) -3-pyrιdm-3-yl-beta-alanm (109) ;N - ({[(5- {[(benzylamino) carbonyl] amino} thien-3-yl) carbonyl] ammo} acetyl) -3-pyridm-3-yl-beta-alanm (109);
ESI-MS [M+H+] = 482.ESI-MS [M + H +] = 482.
N- ( { [ (5-{ [ (Benzylamino) carbonyl] amino}thien-3-yl) carbonyl] - amino}acetyl) -3- (3, 5-dichlorophenyl) -beta-alanin (110); ESI-MS [M+H+] = 549.N- ({[(5- {[(Benzylamino) carbonyl] amino} thien-3-yl) carbonyl] - amino} acetyl) -3- (3,5-dichlorophenyl) beta-alanine (110); ESI-MS [M + H + ] = 549.
N-( { [ (5-{ [ (Benzylamino) carbonyl] amino}thien-3-yl) carbonyl] - amino}acetyl) -3- (4-methylphenyl) -beta-alanin (111); ESI-MS [M+H+] = 495.N- ({[(5- {[(Benzylamino) carbonyl] amino} thien-3-yl) carbonyl] amino} acetyl) -3- (4-methylphenyl) beta-alanine (111); ESI-MS [M + H +] = 495.
(2S)-3- [ ( { [ (5-{ [ (Benzylamino) carbonyl] amino}thien-3-yl) - carbonyl] amino}acetyl)amino] -2-{ [ (benzyloxy) carbonyl] amino} - propanoic acid (112); ESI-MS [M+H+] = 554.(2S) -3- [({[(5- {[(Benzylamino) carbonyl] amino} thien-3-yl) - carbonyl] amino} acetyl) amino] -2- {[(benzyloxy) carbonyl] amino} - propanoic acid (112); ESI-MS [M + H + ] = 554.
N-( { [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-oxazol-5-yl) - carbonyl] amino}acetyl )-3-pyridin-3-yl-beta-alanin (113); ESI-MS [M+H+] = 467. N-( { [ (2-{ [ (Benzylamino) carbonyl] amino}-!, 3-oxazol-5-yl) - carbonyl] amino}acetyl) -3- (3 , 5-dichlorophenyl) -beta- alanin (114) ; ESI-MS [M+H+] = 534.N- ({[(2- {[(Benzylamino) carbonyl] amino} -l, 3-oxazol-5-yl) - carbonyl] amino} acetyl) -3-pyridin-3-yl-beta-alanine (113) ; ESI-MS [M + H + ] = 467. N- ({[(2- {[(Benzylamino) carbonyl] amino} - !, 3-oxazol-5-yl) - carbonyl] amino} acetyl) -3- (3, 5-dichlorophenyl) beta-alanine ( 114); ESI-MS [M + H + ] = 534.
(2S)-3- [ ( { [ (2-{ [ (Benzylamino) carbonyl] amino}-l, 3-oxazol- 5-yl) carbonyl] amino}acetyl) amino] -2-{ [ (benzyloxy) carbonyl] amino}propanoic acid (115);(2S) -3- [({[(2- {[(benzylamino) carbonyl] amino} -l, 3-oxazol-5-yl) carbonyl] amino} acetyl) amino] -2- {[(benzyloxy) carbonyl ] amino} propanoic acid (115);
ESI-MS [M+H+] = 539.ESI-MS [M + H +] = 539.
N-( (2R)-2-{ [ (5-{ [ (Benzylamino)carbonyl]amino}thien-2-yl) carbonyl] amino}propanoyl) -3- (3 , 4-dimethoxypheny1 ) -beta- alanin (116) ;N- ((2R) -2- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3- (3, 4-dimethoxypheny1) -beta- alanine ( 116);
ESI-MS [M+H+] = 555.ESI-MS [M + H + ] = 555.
N-( (2R)-2-{ [ (5-{ [ (Benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino}propanoyl) -3- (4-tert-butylphenyl ) -beta- alanin (117); ESI-MS [M+H+] = 551.N- ((2R) -2- {[(5- {[(benzylamino) carbonyl] amino} thien-2-yl) carbonyl] amino} propanoyl) -3- (4-tert-butylphenyl) beta-alanine ( 117); ESI-MS [M + H + ] = 551.
Synthesesynthesis
Durch die folgende Reaktionssequenz können die N-Substituenten in α-Position zur Carbonsäure breit variiert werden:The following reaction sequence allows the N substituents in the α position to the carboxylic acid to be varied widely:
α-N-Fmoc-ß-N-Aloc-diaminopropansäure (4,52 g) werden wie von P. Sieber (Tetrahedron Lett. 28 (1987) 6147) beschrieben an 5 g Wang-Harz gekuppelt. Anschließend wird die Fmoc-Gruppe durch Anwendung von 20 ml einer Mischung von 10% DBU, 2 % Piperidin und 88% DMF in 3 min abgespalten. Das Harz wird abgesaugt, mehrfach mit DMF, CH2C12 und Diethylether gewaschen und getrocknet. Es resultiert eine Beladung von ca. 1,15 mmol/g.α-N-Fmoc-β-N-Aloc-diaminopropanoic acid (4.52 g) are coupled to 5 g of Wang resin as described by P. Sieber (Tetrahedron Lett. 28 (1987) 6147). The Fmoc group is then split off in 3 minutes by using 20 ml of a mixture of 10% DBU, 2% piperidine and 88% DMF. The resin is sucked off, several times washed with DMF, CH 2 C1 2 and diethyl ether and dried. The result is a loading of approx. 1.15 mmol / g.
Die Einführung von Acylresten in der α-Position gelingt durch 5 Zugabe von 3 eq Carbonsäure und Aktivierung mittels HATU oder TBTU nach den gängigen Standardverfahren innerhalb von 4 h. Zur Einführung von Sulfonylresten werden 0.145 g beladenes Harz in 1 ml CH2C12 suspendiert und eine Lösung von 0,4 eq DMAP, 4 eq Methoxy-trimethylsilyloxy-dimethylketenacetal (MTDA) und 2 eq 10 Sulfonsäurechlorid in 1,5 ml CH2C12 zugegeben (s. M. Gude et al, Tetrahedron Lett. 37 (1996) 8589). Nach 8 h wird abgesaugt und das Harz lOx mit CH2C12, 5x mit DMF und 5x mit CH2C12 gewaschen.Acyl residues can be introduced in the α position by adding 3 eq of carboxylic acid and activation by means of HATU or TBTU within 4 hours using the standard methods. To introduce sulfonyl residues, 0.145 g loaded resin is suspended in 1 ml CH 2 C1 2 and a solution of 0.4 eq DMAP, 4 eq methoxy-trimethylsilyloxy-dimethyl ketene acetal (MTDA) and 2 eq 10 sulfonic acid chloride in 1.5 ml CH 2 C1 2 added (see M. Gude et al, Tetrahedron Lett. 37 (1996) 8589). After 8 hours, is filtered off and the resin is washed lOx with CH 2 C1 2, 5x with DMF and 5 times with CH 2 C1. 2
Für die Abspaltung der Aloe-Gruppe wird das Polymer mit N2 gespült 15 und eine Lösung von 24 eq Phenylsilan in Sauerstofffreiem CHC12 zugegeben (s. N. Thieriet et al., Tetrahedron Lett. 38 (1997) 7275). 0,1 eq Pd(PPh3)4 werden in CH2C12 gelöst zugegeben und die Mischung ca. 90 min umgesetzt.To split off the aloe group, the polymer is flushed with N 2 15 and a solution of 24 eq phenylsilane in oxygen-free CHC1 2 is added (see N. Thieriet et al., Tetrahedron Lett. 38 (1997) 7275). 0.1 eq Pd (PPh 3 ) 4 dissolved in CH 2 C1 2 are added and the mixture is reacted for about 90 min.
20 Anschließend werden 3 eq Fmoc-Aminosäure in DMF nach den gängigen Standardverfahren mit TBTU aktiviert und innerhalb 8 h auf die freie Aminogruppe gekuppelt. Die Abspaltung der Fmoc-Schutzgruppe erfolgt wie bereits oben beschrieben.20 Then 3 eq Fmoc-amino acid in DMF are activated with TBTU according to the standard procedures and coupled to the free amino group within 8 hours. The Fmoc protective group is split off as already described above.
25 Die abschließende Kupplung mit N- (3-Carboxy-thien-5-yl) -NΛ- benzylharnstoff erfolgt analog der obigen Kupplung innerhalb 2d.25 The final coupling with N- (3-carboxy-thien-5-yl) -N Λ - benzylurea takes place analogously to the above coupling within 2d.
Das Harz wird gründlich mit DMF und CH2C12 gewaschen und dann mit 1,5 ml einer Mischung aus 95% TFA und 5% Wasser versetzt. Nach 30 45 min wird abfiltriert und das Harz mit wenig CH2C12 nachgewaschen. Das Filtrat wird vereinigt und eingeengt. Der Rückstand läßt sich durch eine oder mehrere der folgenden Methoden für Testzwecke reinigen:The resin is washed thoroughly with DMF and CH 2 C1 2 and then mixed with 1.5 ml of a mixture of 95% TFA and 5% water. After 30 45 min, the mixture is filtered off and the resin is washed with a little CH 2 C1 2 . The filtrate is combined and concentrated. The residue can be purified for testing by one or more of the following methods:
35 1. Lösen in wenig Methanol und ausfällen durch Zugabe von Wasser. Es wird abgesaugt und getrocknet.35 1. Dissolve in a little methanol and precipitate out by adding water. It is suctioned off and dried.
2. Der Rückstand wird in Ethylacetat gelöst und die Lösung mit Wasser extrahiert. Anschließend wird eingeengt und mit2. The residue is dissolved in ethyl acetate and the solution extracted with water. It is then concentrated and with
40 Diethylether gerührt. Der Niederschlag wird abgesaugt und getrocknet .40 diethyl ether stirred. The precipitate is filtered off and dried.
3. Der Rückstand wird über eine Kieselgelsäule chromato- graphiert. 5 3. The residue is chromatographed on a silica gel column. 5
II. Biologische BeispieleII. Biological examples
Beispiel 1 Integrin 0Cvß3-AssayExample 1 Integrin 0C v ß 3 assay
Zur Identifizierung und Bewertung von Integrin-αvß3 Antagonisten wurde ein Testsystem verwendet, das auf einer Kompetition zwischen dem natürlichen Integrin otvß3-Liganden Vitronectin und der Testsubstanz um die Bindung an Festphasen-gebundenes lntegrin-o-vß3 basiert.For the identification and evaluation of integrin-α v ß 3 antagonists, a test system was used which was based on a competition between the natural integrin ot v ß 3 ligand vitronectin and the test substance around binding to integrin-o- v ß 3 bound to solid phases.
Durchführungexecution
- Microtiterplatten beschichten mit 250 ng/ml Integrin-ovß3 in 0,05 M NaHC03 pH 9,2; 0,1 ml/well;- Coating microtiter plates with 250 ng / ml Integrin-ovß 3 in 0.05 M NaHC0 3 pH 9.2; 0.1 ml / well;
- Absättigen mit 1 % Milchpulver/Assaypuffer; 0,3 ml/well; 0,5 h/RT- Saturate with 1% milk powder / assay buffer; 0.3 ml / well; 0.5 h / rt
- 3x Waschen mit 0,05 % Tween 20/Assaypuffer- Wash three times with 0.05% Tween 20 / assay buffer
- Testsubstanz in 0,1 % Milchpulver/Assaypuffer, 50 μl/well + 0 μg/ml bzw. 2 μg/ml human Vitronectin (Boehriner Ingelheim- Test substance in 0.1% milk powder / assay buffer, 50 μl / well + 0 μg / ml or 2 μg / ml human Vitronectin (Boehriner Ingelheim
T007) in 0,1 % Milchpulver/Assaypuffer, 50 μl/well; 1 h/RTT007) in 0.1% milk powder / assay buffer, 50 μl / well; 1 h / RT
- 3x Waschen mit 0,05 % Tween 20/Assaypuffer- Wash three times with 0.05% Tween 20 / assay buffer
- 1 μg/ml anti human Vitronectin Antikörper gekoppelt an- 1 μg / ml anti human Vitronectin antibody coupled to
Peroxidase (Kordia SAVN-APHRP) in 0,1 % Milchpulver/Assaypuffer; 0,1 ml/well; 1 h/RTPeroxidase (Kordia SAVN-APHRP) in 0.1% milk powder / assay buffer; 0.1 ml / well; 1 h / RT
- 3x Waschen mit 0,05 % Tween 20/Assaypuffer- Wash three times with 0.05% Tween 20 / assay buffer
- 0,1 ml/well Peroxidasesubstrat- 0.1 ml / well peroxidase substrate
- Reaktion stoppen mit 0,1 ml/well 2 M H2S0- Stop reaction with 0.1 ml / well 2 MH 2 S0
- Messung der Absorption bei 450 nm- Measurement of the absorption at 450 nm
Integrin-αvß3 : Human-Placenta wird mit Nonidet solubilisiert und Integrin-θvß3 an einer GRGDSPK-Matrix äffinitätsgereinigt (Elution mit EDTA) . Verunreinigungen durch Integrin ccnbß3 und humanes Serumalbumin sowie das Detergens und EDTA werden durch Anionen- austauschchromatographie entfernt .Integrin-α v ß 3 : Human placenta is solubilized with Nonidet and integrin-θ v ß 3 affinity-cleaned on a GRGDSPK matrix (elution with EDTA). Contamination by integrin ccn b ß 3 and human serum albumin as well as the detergent and EDTA are removed by anion exchange chromatography.
Assaypuffer: 50 mM Tris pH 7,5; 100 mM NaCl; 1 mM CaCl2; 1 mM MgCl2; 10 μM MnCl2 Peroxidasesubstrat: 0,1 ml TMB-Lösung (42 mM TMB in DMSO) und 10 ml Substratpuffer (0,1 m Na-Acetat pH 4,9) mischen, dann Zusatz von 14,7 μl 3 % H202.Assay buffer: 50 mM Tris pH 7.5; 100 mM NaCl; 1 mM CaCl 2 ; 1 mM MgCl 2 ; Mix 10 μM MnCl 2 peroxidase substrate: 0.1 ml TMB solution (42 mM TMB in DMSO) and 10 ml substrate buffer (0.1 m Na acetate pH 4.9), then add 14.7 μl 3% H 2 0 2 .
In dem Assay werden verschiedene Verdünnungen der Testsubstanzen eingesetzt und die ICso-Werte bestimmt (Konzentration desVarious dilutions of the test substances are used in the assay and the IC 50 values are determined (concentration of the
Antagonisten, bei der 50 % des Liganden verdrängt werden) . Die nachstehende Tabelle zeigt die ICso-Werte ausgewählter Beispiele. Antagonists in which 50% of the ligand are displaced). The table below shows the ICso values of selected examples.
Beispiel 2Example 2
Integrin 0Cιrß3-AssayIntegrin 0Cross 3 assay
Der Assay basiert auf einer Kompetition zwischen dem natürlichen Integrin-αnbß3 Liganden Fibrinogen und der Testsubstanz um Bindung an Integrin-αnbß3 -The assay is based on a competition between the natural integrin-αn b ß 3 ligand fibrinogen and the test substance for binding to integrin-αnbß3 -
Durchführungexecution
_ Microtiterplatten beschichten mit 10 μg/ml Fibrinogen (Calbio- chem 341578) in 0,05 M NaHC03 pH 9,2; 0,1 ml/well;_ Coating microtiter plates with 10 μg / ml fibrinogen (Calbiochem 341578) in 0.05 M NaHC0 3 pH 9.2; 0.1 ml / well;
- Absättigen mit 1 % BSA/PBS; 0,3 ml/well; 30 min/RT- Saturate with 1% BSA / PBS; 0.3 ml / well; 30 min / rt
- 3x Waschen mit 0,05 % Tween 20/PBS- Wash three times with 0.05% Tween 20 / PBS
- Testsubstanz in 0,1 % BSA/PBS; 50 μl/well +- test substance in 0.1% BSA / PBS; 50 μl / well +
200 μg/ml Integrin-O-nbßs (Kordia) in 0,1 % BSA/PBS; 50 μl/well; 2 bis 4 h/RT200 µg / ml Integrin-On b ßs (Kordia) in 0.1% BSA / PBS; 50 ul / well; 2 to 4 h / RT
- 3x Waschen wie oben- Wash 3 times as above
- biotinylierter anti Integrin-αnbß3 Antikörper (Dianova CBL 130 B); 1:1000 in 0,1 % BSA/PBS; 0,1 ml/well; 2 bis 4 h/RT- biotinylated anti integrin-αn b ß 3 antibody (Dianova CBL 130 B); 1: 1000 in 0.1% BSA / PBS; 0.1 ml / well; 2 to 4 h / RT
- 3x Waschen wie oben - Streptavidin-Peroxidase Komplex (B.M. 1089153) 1:10000 in 0,1 % BSA/PBS; 0,1 ml/well; 30 min/RT- Wash 3 times as above - streptavidin-peroxidase complex (BM 1089153) 1: 10000 in 0.1% BSA / PBS; 0.1 ml / well; 30 min / rt
- 3x Waschen wie oben- Wash 3 times as above
- 0,1 ml/well Peroxidasesubstrat- 0.1 ml / well peroxidase substrate
- Reaktion stoppen mit 0,1 ml/well 2 M HS04 - Stop reaction with 0.1 ml / well 2 M HS0 4
- Messung der Absorption bei 450 nm- Measurement of the absorption at 450 nm
Peroxidasesubstrat: 0,1 ml TMB-Lösung (42 mM TMB in DMSO) und 10 ml Substratpuffer (0,1 M Na-acetat pH 4,9) mischen, dann Zusatz von 14,7 μl 3 % H202 Peroxidase substrate: Mix 0.1 ml TMB solution (42 mM TMB in DMSO) and 10 ml substrate buffer (0.1 M Na acetate pH 4.9), then add 14.7 μl 3% H 2 0 2
In dem Assay werden verschiedene Verdünnungen der Testsubstanzen eingesetzt und die ICso-Werte bestimmt (Konzentration des Antagonisten, bei der 50 % des Liganden verdrängt werden) . Durch Vergleich der ICso-Werte im Integrin αnbß3- und Integrin 0vb3-Assay kann die Selektivität der Substanzen bestimmt werden.Various dilutions of the test substances are used in the assay and the IC 50 values are determined (concentration of the antagonist at which 50% of the ligand is displaced). The selectivity of the substances can be determined by comparing the IC 50 values in the integrin αn b ß 3 and integrin 0 v b 3 assays.
Beispiel 3 CAM-AssayExample 3 CAM assay
Der CAM (Chorioallantoinmembran) Assay dient als allgemein anerkanntes Modell zur Beurteilung der in vivo Aktivität von Integrin otvß3 _Antagonisten. Er beruht auf der Inhibition von Angiogenese und Neovaskularisation von Tumorgewebe (Am. J. Pathol. 1975, 79, 597-618; Cancer Res . 1980, 40, 2300-2309; Nature 1987, 329, 630). Die Durchführung erfolgt analog zum Stand der Technik. Das Wachstum der Hühnerembryo-Blutgefäße und des transplantierten Tumorgewebes ist gut zu verfolgen und zu bewerten.The CAM (chorioallantoin membrane) assay serves as a generally recognized model for assessing the in vivo activity of integrin ot v ß 3 _ antagonists. It is based on the inhibition of angiogenesis and neovascularization of tumor tissue (Am. J. Pathol. 1975, 79, 597-618; Cancer Res. 1980, 40, 2300-2309; Nature 1987, 329, 630). The implementation is analogous to the state of the art. The growth of the chicken embryo blood vessels and the transplanted tumor tissue is easy to follow and evaluate.
Beispiel 4 Kaninchenaugen-AssayExample 4 Rabbit Eye Assay
In diesem in vivo Modell kann analog zu Beispiel 3 die Inhibition der Angiogenese und Neovaskularisation in Gegenwart von Integrin Otvß3-Antagonisten verfolgt und bewertet werden. Das Modell ist allgemein anerkannt und beruht auf dem Wachstum der Kaninchenblutgefäße ausgehend vom Rand in die Cornea des Auges (Proc. Natl. Acad. Sei. USA. 1994, 91, 4082-4085; Science 1976, 193, 70-72). Die Durchführung erfolgt analog zum Stand der Technik. In this in vivo model, the inhibition of angiogenesis and neovascularization in the presence of integrin Ot v ß 3 antagonists can be monitored and evaluated analogously to Example 3. The model is generally recognized and is based on the growth of rabbit blood vessels from the edge into the cornea of the eye (Proc. Natl. Acad. Sei. USA. 1994, 91, 4082-4085; Science 1976, 193, 70-72). The implementation is analogous to the state of the art.

Claims

Patentansprüche claims
1. Verbindungen der Formel I1. Compounds of formula I.
A—E-G—L IA-E-G-L I
wobei A, E, G und L folgende Bedeutung haben:where A, E, G and L have the following meaning:
L ein Strukturelement der Formel IL,L is a structural element of the formula I L ,
wobei in which
a 0 oder 1,a 0 or 1,
T eine Gruppe COOH oder einen zu COOH hydrolysierbaren Rest,T is a group of COOH or a radical which can be hydrolyzed to COOH,
R2 Wasserstoff, NHS02R21, NHCOR21 oder NHCOOR22,R 2 is hydrogen, NHS0 2 R 21 , NHCOR 21 or NHCOOR 22 ,
wobeiin which
R21 einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cε-Alkyl-, C3-C6-Cycloalkyl-, Cι-C-Alkyl-C3-C6-Cycloalkylrest, C5-Cι2-Bicycloalkyl- oder Cδ-Cis-Tricycloalkylrest, einen mit bis zu drei gleichen oder verschiedenen Resten substituierten Aryl-, Alkylaryl-, Alkylheteroarylrest oder 3- bis 6 gliedrigen, gesättigten, ungesättigten oder aromatischen Heterocyclus, der bis zu drei ver- schiedene oder gleiche Heteroatome 0, N, S enthalten kann, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und dieser Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann, R22 einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cß-Alkylrest oder einen gegebenenfalls substituierten Aryl- oder Alkylarylrest,R 21 is a branched or unbranched, optionally substituted Ci-Cε-alkyl, C 3 -C 6 cycloalkyl, -C-C alkyl-C 3 -C 6 cycloalkyl radical, C 5 -Cι 2 bicycloalkyl or C δ Cis-tricycloalkyl radical, an aryl, alkylaryl, alkylheteroaryl radical which is substituted by up to three identical or different radicals or a 3- to 6-membered, saturated, unsaturated or aromatic heterocycle which has up to three different or identical heteroatoms 0, N, S can contain, where two radicals together can form an fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, and this cycle optionally substituted or a further one on this cycle, optionally substituted, saturated, unsaturated or aromatic cycle can be fused on, R22 is a branched or unbranched, optionally substituted C-C alkyl radical or ß an optionally substituted aryl or alkylaryl,
R3 Wasserstoff oder - (CH )b- (X)c-R31,R 3 is hydrogen or - (CH) b - (X) c -R 31 ,
wobeiin which
b 0, 1, 2 oder 3,b 0, 1, 2 or 3,
c 0 oder 1,c 0 or 1,
X -S02-, -S-, -0-, -CO-, -NH-S02-, -0-CO-, -CO-O-,X -S0 2 -, -S-, -0-, -CO-, -NH-S0 2 -, -0-CO-, -CO-O-,
-NH-CO-, -CO-NH-, -CO-N(R31)-, -N(Rl)-CO-, -S02-NH-, -S02-N(R31)- oder -N(R31) -S02-,-NH-CO-, -CO-NH-, -CO-N (R 31 ) -, -N (Rl) -CO-, -S0 2 -NH-, -S0 2 -N (R 31 ) - or - N (R 31 ) -S0 2 -,
R31 Wasserstoff, eine Hydroxygruppe, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cδ-Alkyl-, Cι-C4-Alkoxy-, -O-Alkylaryl- oder -O-Arylrest, einen primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest, einen gegebenenfalls mit Cι-C-Alkyl oder Aryl substituierten C2-C6-Alkinyl- oder C2-Cg-Alkenylrest, einen C5-Cι2-Bicycloalkyl-, Cβ-Cis-Tricycloalkylrest oder einen mit bis zu drei gleichen oder verschiedenenR 31 is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted Ci-C δ- alkyl, -C-C 4 alkoxy, -O-alkylaryl or -O-aryl radical, a primary or optionally secondary or tertiary substituted amino radical , a C 2 -C 6 alkynyl or C 2 -Cg alkenyl radical optionally substituted with C 1 -C 4 alkyl or aryl, a C 5 -C 2 bicycloalkyl, Cβ-cis-tricycloalkyl radical or one with up to three of the same or different
Resten substituierten, 3- bis 6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome O, N, S enthalten kann, C3-C8-Cycloalkyl-, Aryl- oder Hetero- arylrest, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann,Residues substituted, 3- to 6-membered, saturated or unsaturated heterocycle, which can contain up to three different or identical heteroatoms O, N, S, C 3 -C 8 cycloalkyl, aryl or heteroaryl radical, two radicals together a fused, saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, can represent and the cycle optionally substituted or on this cycle another, optionally substituted, saturated, unsaturated or aromatic Cycle can be condensed,
undand
R4 Wasserstoff, oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι_4-Alkyl-, C3-Cδ- Alkenyl-, C3-C6-Alkinyl- oder C3-C6-Cycloalkylrest,R4 is hydrogen, or a branched or unbranched, optionally substituted Cι_ 4 alkyl, C 3 -C δ - alkenyl, C 3 -C 6 alkynyl or C 3 -C 6 cycloalkyl,
bedeuten, G ein Strukturelement der Formel IG,mean, G is a structural element of the formula I G ,
wobei in which
d 0, 1 oder 2,d 0, 1 or 2,
R5 Wasserstoff, eine Hydroxygruppe, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C6-Alkyl-, C!-C4-Alkoxy, -O-Alkylaryl- oder -O-Arylrest, einen primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest, einen gegebenenfalls mit Cι-C4-Alkyl oder Aryl substituierten C2-C6-Alkinyl- oder C2-Cg-Alkenylrest, einen C5-Cι2-Bicycloalkyl-, Cδ-Cig-Tricycloalkylrest oder einen mit bis zu drei gleichen oder verschiedenenR 5 is hydrogen, a hydroxy group, a branched or unbranched, optionally substituted C 1 -C 6 alkyl, C ! -C 4 -alkoxy, -O-alkylaryl or -O-aryl radical, a primary or optionally secondary or tertiary substituted amino radical, a C 2 -C 6 -alkynyl or C 2 optionally substituted with C 1 -C 4 -alkyl or aryl -Cg alkenyl, a C 5 -C 2 bicycloalkyl, C δ -Cig tricycloalkyl or one with up to three identical or different
Resten substituierten, 3- bis 6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, C3_8-Cycloalkyl-, Aryl- oder Heteroaryl- rest, wobei zwei Reste zusammen einen gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome O, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substi- tuiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann, oder die Seitenkette einer natürlichen Aminosäure,Radicals substituted, 3- to 6-membered, saturated or unsaturated heterocycle containing up to three different or identical heteroatoms 0, N, which may contain S, C 3 _ 8 cycloalkyl radical, aryl or heteroaryl, where two radicals together form a saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms O, N, S, and the cycle is optionally substituted or on this cycle another, optionally substituted, saturated, unsaturated or aromatic cycle can be condensed, or the side chain of a natural amino acid,
R6 Wasserstoff, oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-4-Alkyl-, C3-Cg- Alkenyl-, C3-Cg-Alkinyl- oder C3-C6-Cycloalkylrest bedeuten,R 6 is hydrogen, or a branched or unbranched, optionally substituted Cι- 4 alkyl, C 3 -Cg- alkenyl, C3 -CG-alkynyl or C 3 -C 6 cycloalkyl,
E ein Strukturelement der Formel IE E is a structural element of the formula I E
-(NH)g-(CH2)f-Q-(CH2)e-CO- IE - (NH) g - (CH 2 ) f -Q- (CH 2 ) e -CO- I E
wobei e 0, 1 oder 2,in which e 0, 1 or 2,
f 0 oder 1,f 0 or 1,
g 0 oder 1,g 0 or 1,
Q ein zweifach gebundener, gegebenenfalls substituierter Heteroarylrest, wobei zwei Substituenten zusammen einen gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und dieser Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann,Q is a double-bonded, optionally substituted heteroaryl radical, where two substituents together can represent a saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, and this cycle optionally substituted or on this cycle a further, optionally substituted, saturated, unsaturated or aromatic cycle can be fused on,
A eines der Strukturelemente der Formeln IA 1 bis IA 20,A one of the structural elements of the formulas I A 1 to I A 20 ,
wobei in which
Rio, Rii unabhängig voneinander Wasserstoff, - (CH2)h~ (Y)i-R101, oder beide Reste zusammen einen 3 bis 8 gliedrigen, gegebenenfalls substituierten, gesättigten ungesättigten oder aromatischen N-Heterocyclus der zusätzlich zwei weitere, gleiche oder verschiedene Heteroatome 0, N oder S enthalten kann,R i o, R ii independently of one another hydrogen, - (CH 2 ) h ~ (Y) iR 101 , or both radicals together form a 3 to 8-membered, optionally substituted, saturated unsaturated or aromatic N-heterocycle of the two additional, identical or can contain different heteroatoms 0, N or S,
wobeiin which
h 0, 1, 2 oder 3,h 0, 1, 2 or 3,
i 0 oder 1,i 0 or 1,
Y -S02-, -S-, -0-, -CO-, -NH-S02-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R101)-, -N(R101) -CO-, -S02-NH-, -N(R101)-SO2- oder -S02-N(R101) - undY -S0 2 -, -S-, -0-, -CO-, -NH-S0 2 -, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, - CO-N (R 101 ) -, -N (R 101 ) -CO-, -S0 2 -NH-, -N (R 101 ) -SO 2 - or -S0 2 -N (R 101 ) - and
R101 eine Hydroxygruppe, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Ci-Cg-Alkyl-, Cχ-C4-Alkoxy, -O-Alkylaryl- oder -O-Aryl-, einen primär oder gegebenenfalls sekundär oder tertiär substituierten Aminorest, einen gegebenenfalls mit Cχ-C4-Alkyl oder Aryl substituierten C2-C6~Alkinyl- oder C -C6~Alkenylrest, einen Cs-Cι2-Bicycloalkyl-, C6-Ci8-Tricycloalkylrest oder einen mit bis zu drei gleichen oder verschiedenen Resten substituierten, 3- bis 6 gliedrigen, gesättigten oder ungesättigten Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, C3_8-Cycloalkyl-, Aryl- oder Heteroarylrest, wobei zwei Reste zusammen einen anelierten, gesättigten, ungesättigten oder aromatischen Carbocyclus oder Heterocyclus, der bis zu drei verschiedene oder gleiche Heteroatome 0, N, S enthalten kann, darstellen können und der Cyclus gegebenenfalls substituiert oder an diesem Cyclus ein weiterer, gegebenenfalls substituierter, gesättigter, ungesättigter oder aromatischer Cyclus ankondensiert sein kann,R 101 is a hydroxyl group, a branched or unbranched, optionally substituted Ci-Cg-alkyl, Cχ-C 4 alkoxy, -O-alkylaryl or -O-aryl, a primary or optionally secondary or tertiary substituted amino radical, one optionally with Cχ-C 4 alkyl or aryl substituted C 2 -C 6 ~ alkynyl or C -C 6 ~ alkenyl radical, a Cs -C 2 bicycloalkyl, C 6 -Ci 8 tricycloalkyl radical or one with up to three of the same or various residues substituted, 3- to 6-membered, saturated or unsaturated heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, C 3 _ 8 -cycloalkyl, aryl or heteroaryl residue, two residues together fused together , saturated, unsaturated or aromatic carbocycle or heterocycle, which can contain up to three different or identical heteroatoms 0, N, S, can represent and the cycle optionally substituted or on this cycle another, optionally substi tuated, saturated, unsaturated or aromatic cycle can be fused,
R12 einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cχ-C4-Alkyl-, Alkylaryl-, C3-C6~Cyclo- alkyl- oder Cι-C4-Alkyl-C3-C6-Cycloalkylrest oder einen gegebenenfalls substituierten Arylrest, R13 Wasserstoff, -OH, -CN, -CONH2/ einen verzweigten oder unverzweigten, gegebenenfalls substituierten C1-C4-Alkyl-, Cι-C4-Alkoxy- oder -0-CO-Cι-C4-Alkylrest, oder einen gegebenenfalls substituierten Alkylaryl-, -O-Alkylaryl-, -O-CO-Aryl-, -O-CO-Alkylaryl- oder -O-CO-Allylrest,R 12 is a branched or unbranched, optionally substituted Cχ-C 4 alkyl, alkylaryl, C 3 -C 6 ~ cycloalkyl or C 1 -C 4 alkyl C 3 -C 6 cycloalkyl radical or an optionally substituted aryl radical , R 13 is hydrogen, -OH, -CN, -CONH 2 / a branched or unbranched, optionally substituted C 1 -C 4 -alkyl, -C-C 4 -alkoxy or -0-CO-Cι-C 4 -alkyl radical, or an optionally substituted alkylaryl, -O-alkylaryl, -O-CO-aryl, -O-CO-alkylaryl or -O-CO-allyl radical,
R14 Wasserstoff, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl-, -CO-0-Cι-C4-Alkyl- Alkylaryl-, -CO-O-Alkylaryl-, -CO-O-Allyl-, -CO-Cι-C-Alkyl- , -CO-Alkylaryl- oderR 14 is hydrogen, a branched or unbranched, optionally substituted C 1 -C 4 -alkyl, -CO-0-C 1 -C 4 -alkyl-alkylaryl-, -CO-O-alkylaryl-, -CO-O-allyl-, -CO-C-C-alkyl, -CO-alkylaryl or
-CO-Allylrest,-CO-allyl residue,
R15 Wasserstoff, einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkylrest oder einen gegebenenfalls substituierten Aryl- oder Alkylarylrest,R 15 is hydrogen, a branched or unbranched, optionally substituted C 1 -C 4 -alkyl radical or an optionally substituted aryl or alkylaryl radical,
R16, R17 unabhängig voneinander -NH2, Halogen oder einen verzweigten oder unverzweigten, gegebenenfalls substituierten Cι-C4-Alkyl- oder Cι-C4-Alkoxyrest oder einen, gegebenenfalls substituierten Arylrest,R 16 , R 17 independently of one another are -NH 2 , halogen or a branched or unbranched, optionally substituted C 1 -C 4 -alkyl or C 1 -C 4 alkoxy radical or an optionally substituted aryl radical,
Z1 ' Z2 ' Z3 ' Z4 unabhängig voneinander CH, C-CH3, C-OCH3/ C-Cl oder NZ 1 ' Z 2 ' Z 3 ' Z 4 independently of one another CH, C-CH 3 , C-OCH 3 / C-Cl or N
bedeuten, sowie die physiologisch verträglichen Salze,mean, as well as the physiologically acceptable salts,
Prodrugs und die enantiomerenremen oder diastereomerenreinen und tautomeren Formen.Prodrugs and the enantiomerically or diastereomerically pure and tautomeric forms.
2. Arzneimittelzubereitungen zur peroralen und parenteralen Anwendung, enthaltend neben den üblichen Arzneimittelhilfsstoffen mindestens eine Verbindung gemäß Anspruch 1.2. Pharmaceutical preparations for oral and parenteral use, comprising, in addition to the usual pharmaceutical excipients, at least one compound according to claim 1.
3. Verwendung der Verbindungen gemäß Anspruch 1 zur Herstellung von Arzneimitteln zur Behandlung von Krankheiten.3. Use of the compounds according to claim 1 for the manufacture of medicaments for the treatment of diseases.
4. Verwendung der Verbindungen gemäß Anspruch 1 nach Anspruch 3 als Integrin-Rezeptorantagonisten.4. Use of the compounds according to claim 1 according to claim 3 as integrin receptor antagonists.
5. Verwendung der Verbindungen gemäß Anspruch 1 nach Anspruch 4 als Antagonisten des αvß3~Integrinrezeptors.5. Use of the compounds according to claim 1 according to claim 4 as antagonists of the αvß 3 ~ integrin receptor.
6. Verwendung der Verbindungen gemäß Anspruch 1 zur Herstellung von Arzneimitteln zur Behandlung von Krankheiten, in die ein Integrinrezeptor involviert ist. 6. Use of the compounds according to claim 1 for the manufacture of medicaments for the treatment of diseases in which an integrin receptor is involved.
7. Verwendung der Verbindungen gemäß Anspruch 1 nach Anspruch 6 zur Behandlung von Krankheiten, in die der αvß3~Integrinrezeptor involviert ist.7. Use of the compounds according to claim 1 according to claim 6 for the treatment of diseases in which the α v ß 3 ~ integrin receptor is involved.
8. Verwendung der Verbindungen gemäß Anspruch 1 nach Anspruch 7 zur Behandlung von Atherosklerose, rheumatoider Arthritis, Restenose nach Gefäßverletzung, Angioplastie, akutem Nieren- versagen, Angiogenese-assoziierte Mikroangiopathien, dia- betischen Angiopathien, Blutplättchenvermitteltem vaskulärem Verschluß, arterieller Thrombose, kongestivem Herzversagen, Myokardinfarkt, Schlaganfall, Krebs, Osteoporose, Bluthochdruck, Psoriasis oder viralen, parasitären oder bakteriellen Erkrankungen, Entzündungen, Wundheilung, Hyperparathyroismus, Paget' scher Erkrankung, maligne Hypercalcemie oder meta- statische osteolytische Läsionen.8. Use of the compounds according to claim 1 according to claim 7 for the treatment of atherosclerosis, rheumatoid arthritis, restenosis after vascular injury, angioplasty, acute renal failure, angiogenesis-associated microangiopathies, diabetic angiopathies, platelet-mediated vascular occlusion, arterial thrombosis, congestive heart disease Myocardial infarction, stroke, cancer, osteoporosis, high blood pressure, psoriasis or viral, parasitic or bacterial diseases, inflammation, wound healing, hyperparathyroism, Paget's disease, malignant hypercalcemia or metatic static osteolytic lesions.
9. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der9. A pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the
Gruppegroup
Inhibitoren der Blutplättchenadhäsion, -aktivierung oderInhibitors of platelet adhesion, activation or
-aggregation,aggregation,
Antikoagulantia, die die Thrombinaktivität oder -bildung verhindern,Anticoagulants that prevent thrombin activity or formation
Antagonisten von blutplattchenaktivierenden Verbindungen oderAntagonists of blood platelet activating compounds or
Selectin-Antagonisten.Selectin antagonists.
10. Verwendung der Arzneimittelzubereitung gemäß Anspruch 9 zur Herstellung eines Arzneimittels zur Behandlung von blutplättchenvermitteltem vaskulärem Verschluß oder Thrombose.10. Use of the pharmaceutical preparation according to claim 9 for the manufacture of a medicament for the treatment of platelet-mediated vascular occlusion or thrombosis.
11. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfs- Stoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe11. A pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group
Inhibitoren der Blutplättchenaktivierung oder -aggregation,Inhibitors of platelet activation or aggregation,
Serin-Protease Inhibitoren,Serine protease inhibitors,
Fibrinogen-senkende Verbindungen, Selectin-Antagonisten,Fibrinogen-lowering compounds, selectin antagonists,
Antagonisten von ICAM-1 oder VCAM-1Antagonists of ICAM-1 or VCAM-1
Inhibitoren der LeukozytenadhäsionInhibitors of leukocyte adhesion
Inhibitoren der Gefäßwandtransmigration,Inhibitors of vascular wall transmigration,
Fibrinolyse-modulierende Verbindungen, Inhibitoren von Komplementfaktoren,Fibrinolysis-modulating compounds, inhibitors of complement factors,
Endothelinrezeptor-Antagonisten,Endothelin receptor antagonists,
Tyrosinkinase-Inhibitoren, Antioxidantien oder Interleukin 8 Antagonisten.Tyrosine kinase inhibitors, Antioxidants or Interleukin 8 antagonists.
12. Verwendung der Arzneimittelzubereitung gemäß Anspruch 11 zur Herstellung eines Arzneimittels zur Behandlung von Myokard- infarkt oder Schlaganfall .12. Use of the pharmaceutical preparation according to claim 11 for the manufacture of a medicament for the treatment of myocardial infarction or stroke.
13. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfs- Stoffe und mindestens eine weitere Verbindung, ausgewählt aus der13. Pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the
Gruppegroup
Endothelinantagonisten,Endothelin antagonists,
ACE-Inhibitoren, Angiotensinrezeptorantagonisten,ACE inhibitors, angiotensin receptor antagonists,
Endopeptidase Inhibitoren,Endopeptidase inhibitors,
Beta-Blocker,Beta blocker,
Kaiziumkanal-Antagonisten,Silicon channel antagonists,
Phosphodiesterasehemmer oder Caspaseinhibitoren.Phosphodiesterase inhibitors or caspase inhibitors.
14. Verwendung der Arzneimittelzubereitung gemäß Anspruch 13 zur Herstellung eines Arzneimittels zur Behandlung von kongestivem Herzversagen.14. Use of the pharmaceutical preparation according to claim 13 for the manufacture of a medicament for the treatment of congestive heart failure.
15. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe Thrombininhibitoren,15. A pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group consisting of thrombin inhibitors,
Inhibitoren des Faktors Xa,Inhibitors of factor Xa,
Inhibitoren des Koagulationsweges der zur Thrombinbildung führt,Inhibitors of the coagulation pathway leading to thrombin formation,
Inhibitoren der Blutplättchenadhäsion, -aktivierung oder -aggregation,Inhibitors of platelet adhesion, activation or aggregation,
Endothelinrezeptor-Antagonisten,Endothelin receptor antagonists,
Stickstoffoxidsynthasehemmer,Nitric oxide synthase inhibitor,
CD44-Antagonisten,CD44 antagonists,
Selectin-Antagonisten, MCP-1-Antagonisten,Selectin antagonists, MCP-1 antagonists,
Inhibitoren der Signaltransduktion in proliferierendenInhibitors of signal transduction in proliferating
Zellen,Cells,
Antagonisten der durch EGF, PDGF, VEGF oder bFGF vermitteltenAntagonists of those mediated by EGF, PDGF, VEGF or bFGF
Zellantwort oder Antioxidantien. Cell response or antioxidants.
16. Verwendung der Arzneimittelzubereitung gemäß Anspruch 15 zur Herstellung eines Arzneimittels zur Behandlung von Restenose nach Gefäßverletzung oder Stentimplantation.16. Use of the pharmaceutical preparation according to claim 15 for the manufacture of a medicament for the treatment of restenosis after vascular injury or stent implantation.
5 17. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe17. Medicament preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group
10 Antagonisten der durch EGF, PDGF, VEGF oder bFGF vermittelten Zellantwort,10 antagonists of the cell response mediated by EGF, PDGF, VEGF or bFGF,
Heparin oder niedermolekulare Heparine oder weitere GAGs, Inhibitoren von MMPs, Selectin-Antagonisten,Heparin or low molecular weight heparins or other GAGs, inhibitors of MMPs, selectin antagonists,
15 Endothelin-Antagonisten, ACE-Inhibitoren,15 endothelin antagonists, ACE inhibitors,
Angiotensinrezeptor-Antagonisten, Glycosilierungshemmer oder AGE-Bildungs-Inhibitoren und Antagonisten Ihrer Rezeptoren.Angiotensin receptor antagonists, glycosylation inhibitors or AGE formation inhibitors and antagonists of your receptors.
2020th
18. Verwendung der Arzneimittelzubereitung gemäß Anspruch 17 zur Herstellung eines Arzneimittels zur Behandlung von diabetischen Angiopathien.18. Use of the pharmaceutical preparation according to claim 17 for the manufacture of a medicament for the treatment of diabetic angiopathies.
25 19. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe fettsenkende Verbindungen,19. Medicament preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group of fat-lowering compounds,
30 Selectin-Antagonisten,30 selectin antagonists,
Antagonisten von ICAM-I oder VCAM-1Antagonists of ICAM-I or VCAM-1
Heparin oder niedermolekulare Heparine oder weitere GAGs,Heparin or low molecular weight heparins or other GAGs,
Inhibitoren von MMPs,Inhibitors of MMPs,
Endothelinantagonisten,Endothelin antagonists,
35 Apolipoprotein Al-Antagonisten, Cholesterol-Antagonisten, HMG CoA Reduktase-lnhibitoren, ACAT Inhibitoren, ACE Inhibitoren, 0 Angiotensinrezeptorantagonisten, Tyrosinkinaseinhibitoren, Proteinkinase C-Inhibitoren, Kalzium-Kanal-Antagonisten, LDL-Rezeptor-Funktionsstimulantien, 5 Antioxidantiren oder Freie Radikal-Fanger. 35 apolipoprotein Al antagonists, cholesterol antagonists, HMG CoA reductase inhibitors, ACAT inhibitors, ACE inhibitors, 0 angiotensin receptor antagonists, tyrosine kinase inhibitors, protein kinase C inhibitors, calcium channel antagonists, LDL receptor or antioxidant functional 5-free stimulant antioxidants Catcher.
20. Verwendung der Arzneimittelzubereitung gemäß Anspruch 19 zur Herstellung eines Arzneimittels zur Behandlung von Atherosklerose .20. Use of the pharmaceutical preparation according to claim 19 for the manufacture of a medicament for the treatment of atherosclerosis.
21. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe cytostatische oder antineoplastische Verbindungen, Verbindungen die die Proliferation inhibieren oder Heparin oder niedermolekulare Heparine oder weitere GAGs.21. Pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group consisting of cytostatic or antineoplastic compounds, compounds which inhibit proliferation or heparin or low molecular weight heparins or other GAGs.
22. Verwendung der Arzneimittelzubereitung gemäß Anspruch 21 zur Herstellung eines Arzneimittels zur Behandlung von Krebs.22. Use of the pharmaceutical preparation according to claim 21 for the manufacture of a medicament for the treatment of cancer.
23. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe23. A pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group
Verbindungen zur Anti-resorptiven Therapie,Connections to anti-resorptive therapy,
Verbindungen zur Hormon-Austausch-Therapie,Connections to hormone exchange therapy,
Rekombinantes humanes Wachstumshormon,Recombinant human growth hormone,
Bisphosphonate, Verbindungen zur Calcitonintherapie,Bisphosphonates, compounds for calcitonin therapy,
Calcitoninstimulantien,Calcitonin stimulants,
Kalzium-Kanal-Antagonisten,Calcium channel antagonists,
Knochenbildungsstimulantien, lnterleukin-6-Antagonisten oder Src Tyrosinkinase-Inhibitoren.Bone formation stimulants, interleukin-6 antagonists or Src tyrosine kinase inhibitors.
24. Verwendung der Arzneimittelzubereitung gemäß Anspruch 23 zur Herstellung eines Arzneimittels zur Behandlung von Osteoporose.24. Use of the pharmaceutical preparation according to claim 23 for the manufacture of a medicament for the treatment of osteoporosis.
25. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe25. Pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group
TNF-Antagonisten,TNF antagonists,
Antagonisten von VLA-4 oder VCAM-1,VLA-4 or VCAM-1 antagonists,
Antagonisten von LFA-1, Mac-1 oder ICAMs,Antagonists of LFA-1, Mac-1 or ICAMs,
Komplementinhibitoren, Immunosuppressiva,Complement inhibitors, immunosuppressants,
Interleukin-1-, -5- oder -8-Antagonisten oder Dihydrofolatreduktase-Inhibitoren.Interleukin-1, -5 or -8 antagonists or Dihydrofolate reductase inhibitors.
26. Verwendung der Arzneimittelzubereitung gemäß Anspruch 25 zur Herstellung eines Arzneimittels zur Behandlung von rheumatoider Arthritis.26. Use of the pharmaceutical preparation according to claim 25 for the manufacture of a medicament for the treatment of rheumatoid arthritis.
27. Arzneimittelzubereitung, enthaltend mindestens eine Verbindung gemäß Anspruch 1, gegebenenfalls Arzneimittelhilfsstoffe und mindestens eine weitere Verbindung, ausgewählt aus der Gruppe Collagenase, PDGF-Antagonisten oder MMPs.27. A pharmaceutical preparation containing at least one compound according to claim 1, optionally pharmaceutical excipients and at least one further compound selected from the group consisting of collagenase, PDGF antagonists or MMPs.
28. Verwendung der Arzneimittelzubereitung gemäß Anspruch 27 zur Herstellung eines Arzneimittels zur Verbesserung der Wundheilung. 28. Use of the medicament preparation according to claim 27 for the manufacture of a medicament for improving wound healing.
EP00926971A 1999-04-28 2000-04-17 Integrin receptor antagonists Withdrawn EP1173468A1 (en)

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DE1999119218 DE19919218A1 (en) 1999-04-28 1999-04-28 New peptide compounds, e.g. aza-heterocyclic substituted beta-alanine derivatives, are integrin receptor antagonists useful e.g. for treating atherosclerosis, cancer, osteoporosis, hypertension or inflammation
DE19919218 1999-04-28
DE19948269 1999-10-06
DE1999148269 DE19948269A1 (en) 1999-10-06 1999-10-06 New compounds as integrin antagonists useful for treating e.g. cardiovascular disorders, rheumatoid arthritis, kidney failure, stroke, cancer, osteoporosis, psoriasis or infection
PCT/EP2000/003469 WO2000066618A1 (en) 1999-04-28 2000-04-17 Integrin receptor antagonists

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AU4551500A (en) 2000-11-17
CZ20013846A3 (en) 2002-06-12
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RU2001132141A (en) 2004-03-20
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CN1355811A (en) 2002-06-26
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WO2000066618A1 (en) 2000-11-09
PL352777A1 (en) 2003-09-08
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