EP1173466A4 - Verfahren zur vermeidung der bindung von leukozyten an fibrinogen - Google Patents

Verfahren zur vermeidung der bindung von leukozyten an fibrinogen

Info

Publication number
EP1173466A4
EP1173466A4 EP00930252A EP00930252A EP1173466A4 EP 1173466 A4 EP1173466 A4 EP 1173466A4 EP 00930252 A EP00930252 A EP 00930252A EP 00930252 A EP00930252 A EP 00930252A EP 1173466 A4 EP1173466 A4 EP 1173466A4
Authority
EP
European Patent Office
Prior art keywords
fibrinogen
leukocyte adhesion
inhibiting leukocyte
inhibiting
adhesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00930252A
Other languages
English (en)
French (fr)
Other versions
EP1173466A1 (de
Inventor
David P O'connell
Elisabeth Wann
Magnus Hook
Timothy J Foster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Texas A&M University System
Original Assignee
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Texas A&M University System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin, Texas A&M University System filed Critical College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Publication of EP1173466A1 publication Critical patent/EP1173466A1/de
Publication of EP1173466A4 publication Critical patent/EP1173466A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP00930252A 1999-04-28 2000-04-28 Verfahren zur vermeidung der bindung von leukozyten an fibrinogen Withdrawn EP1173466A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13240499P 1999-04-28 1999-04-28
US132404P 1999-04-28
PCT/US2000/011685 WO2000064925A1 (en) 1999-04-28 2000-04-28 Method of inhibiting leukocyte adhesion to fibrinogen

Publications (2)

Publication Number Publication Date
EP1173466A1 EP1173466A1 (de) 2002-01-23
EP1173466A4 true EP1173466A4 (de) 2002-10-16

Family

ID=22453897

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00930252A Withdrawn EP1173466A4 (de) 1999-04-28 2000-04-28 Verfahren zur vermeidung der bindung von leukozyten an fibrinogen

Country Status (4)

Country Link
EP (1) EP1173466A4 (de)
AU (1) AU4810600A (de)
CA (1) CA2367830A1 (de)
WO (1) WO2000064925A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002256985B8 (en) 2001-01-26 2008-03-20 Inhibitex, Inc Monoclonal antibodies to the ClfA protein and method of use in treating or preventing infections
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
CN101951948B (zh) 2007-08-31 2015-12-09 芝加哥大学 与针对葡萄球菌性肺部疾病和病症进行免疫相关的方法和组合物
AU2012216332B8 (en) * 2008-01-31 2015-04-30 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Treatment of microbial infections
JP5709527B2 (ja) * 2008-01-31 2015-04-30 ザ プロボスト フェローズ アンドスカラーズ オブ ザ カレッジ オブ ザ ホーリー アンド アンディバイデッドトリニティー オブ クイーン エリザベス ニア ダブリン 微生物感染症の治療
WO2011005341A2 (en) 2009-04-03 2011-01-13 University Of Chicago Compositions and methods related to protein a (spa) variants
CA2768485C (en) 2009-07-16 2018-12-04 Timothy Foster Treatment of staphylococci infections using recombinant fibrinogen binding protein clumping factor a
CA2803298C (en) 2010-07-02 2020-07-14 The University Of Chicago Compositions and methods related to protein a (spa) variants
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008341A (en) * 1994-08-22 1999-12-28 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
O'CONNELL D P ET AL: "The fibrinogen-binding MSCRAMM (clumping factor) of Staphylococcus aureus has a Ca2+-dependent inhibitory site.", JOURNAL OF BIOLOGICAL CHEMISTRY, (1998 MAR 20) 273 (12) 6821-9., XP002195398 *

Also Published As

Publication number Publication date
CA2367830A1 (en) 2000-11-02
WO2000064925A1 (en) 2000-11-02
WO2000064925A9 (en) 2002-06-27
AU4810600A (en) 2000-11-10
EP1173466A1 (de) 2002-01-23

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