EP1173466A4 - Verfahren zur vermeidung der bindung von leukozyten an fibrinogen - Google Patents
Verfahren zur vermeidung der bindung von leukozyten an fibrinogenInfo
- Publication number
- EP1173466A4 EP1173466A4 EP00930252A EP00930252A EP1173466A4 EP 1173466 A4 EP1173466 A4 EP 1173466A4 EP 00930252 A EP00930252 A EP 00930252A EP 00930252 A EP00930252 A EP 00930252A EP 1173466 A4 EP1173466 A4 EP 1173466A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- fibrinogen
- leukocyte adhesion
- inhibiting leukocyte
- inhibiting
- adhesion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000008946 Fibrinogen Human genes 0.000 title 1
- 108010049003 Fibrinogen Proteins 0.000 title 1
- 229940012952 fibrinogen Drugs 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000023404 leukocyte cell-cell adhesion Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13240499P | 1999-04-28 | 1999-04-28 | |
US132404P | 1999-04-28 | ||
PCT/US2000/011685 WO2000064925A1 (en) | 1999-04-28 | 2000-04-28 | Method of inhibiting leukocyte adhesion to fibrinogen |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1173466A1 EP1173466A1 (de) | 2002-01-23 |
EP1173466A4 true EP1173466A4 (de) | 2002-10-16 |
Family
ID=22453897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00930252A Withdrawn EP1173466A4 (de) | 1999-04-28 | 2000-04-28 | Verfahren zur vermeidung der bindung von leukozyten an fibrinogen |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1173466A4 (de) |
AU (1) | AU4810600A (de) |
CA (1) | CA2367830A1 (de) |
WO (1) | WO2000064925A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002256985B8 (en) | 2001-01-26 | 2008-03-20 | Inhibitex, Inc | Monoclonal antibodies to the ClfA protein and method of use in treating or preventing infections |
US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
CN101951948B (zh) | 2007-08-31 | 2015-12-09 | 芝加哥大学 | 与针对葡萄球菌性肺部疾病和病症进行免疫相关的方法和组合物 |
AU2012216332B8 (en) * | 2008-01-31 | 2015-04-30 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | Treatment of microbial infections |
JP5709527B2 (ja) * | 2008-01-31 | 2015-04-30 | ザ プロボスト フェローズ アンドスカラーズ オブ ザ カレッジ オブ ザ ホーリー アンド アンディバイデッドトリニティー オブ クイーン エリザベス ニア ダブリン | 微生物感染症の治療 |
WO2011005341A2 (en) | 2009-04-03 | 2011-01-13 | University Of Chicago | Compositions and methods related to protein a (spa) variants |
CA2768485C (en) | 2009-07-16 | 2018-12-04 | Timothy Foster | Treatment of staphylococci infections using recombinant fibrinogen binding protein clumping factor a |
CA2803298C (en) | 2010-07-02 | 2020-07-14 | The University Of Chicago | Compositions and methods related to protein a (spa) variants |
US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6008341A (en) * | 1994-08-22 | 1999-12-28 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
-
2000
- 2000-04-28 WO PCT/US2000/011685 patent/WO2000064925A1/en not_active Application Discontinuation
- 2000-04-28 CA CA002367830A patent/CA2367830A1/en not_active Abandoned
- 2000-04-28 AU AU48106/00A patent/AU4810600A/en not_active Abandoned
- 2000-04-28 EP EP00930252A patent/EP1173466A4/de not_active Withdrawn
Non-Patent Citations (1)
Title |
---|
O'CONNELL D P ET AL: "The fibrinogen-binding MSCRAMM (clumping factor) of Staphylococcus aureus has a Ca2+-dependent inhibitory site.", JOURNAL OF BIOLOGICAL CHEMISTRY, (1998 MAR 20) 273 (12) 6821-9., XP002195398 * |
Also Published As
Publication number | Publication date |
---|---|
CA2367830A1 (en) | 2000-11-02 |
WO2000064925A1 (en) | 2000-11-02 |
WO2000064925A9 (en) | 2002-06-27 |
AU4810600A (en) | 2000-11-10 |
EP1173466A1 (de) | 2002-01-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP970604B1 (en) | Novel heterocycles as inhibitors of leukocyte adhesion and as antagonists of vla-4 | |
PL344488A1 (en) | Method of bonding metal parts to plastic materials | |
HK1045157A1 (zh) | 抑制vla-4介導的白細胞粘着的化合物 | |
PL339173A1 (en) | Derivatives of benzamidine as inhibitors of factor xa | |
IL133639A0 (en) | Dipeptide and related compounds which inhibit leukocyte adhesion mediated by vla-4 | |
IL149118A0 (en) | Inhibitors of neuraminidases | |
IL133641A0 (en) | Compounds which inhibit leukocyte adhesion mediated by vla-4 | |
HUP0002682A3 (en) | Dipeptide compounds which inhibit leukocyte adhesion mediated by vla-4 | |
PL320995A1 (en) | Fibronectin adhesion inhibitors | |
GB2345790B (en) | Method for improving adhesion to copper | |
EG23980A (en) | Potassium salt of (s)-omeprazole | |
HUP9801991A3 (en) | Proline derivatives useful as inhibitors of human leukocyte elastase | |
IL144274A0 (en) | Derivatives of monosaccharides as cell adhesion inhibitors | |
EP1173466A4 (de) | Verfahren zur vermeidung der bindung von leukozyten an fibrinogen | |
EP1049716A4 (de) | Aufreinigung von fibrinogen | |
AU1183101A (en) | Method relating to anodic bonding | |
HK1041270A1 (en) | 2,-3-o-isoproylidene derivatives of monosaccharides as cell adhesion inhibitors | |
IL138601A0 (en) | Pyrrolidines as inhibitors of neuraminidases | |
HK1046146B (zh) | 可以抑制由vla-4介導的白細胞粘着的焦谷氨酸衍生物及相關化合物 | |
HK1044549B (zh) | 可以抑制由vla-4介導的白細胞粘着的化合物 | |
GB2389182B (en) | Method of purifying b-secretase | |
AU3899200A (en) | Treatment to lower platelet adhesiveness | |
PL336405A1 (en) | Method of purifying isoquinoline | |
GB9924752D0 (en) | Method of construction | |
PL331398A1 (en) | Method of purifying crude salicylic acid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20011030 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 07K 1/00 A, 7C 07K 14/00 B, 7C 07K 17/00 B, 7C 07K 14/31 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20020902 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20021116 |