EP1169449A2 - Proteines transmembranaires clasp-2 - Google Patents

Proteines transmembranaires clasp-2

Info

Publication number
EP1169449A2
EP1169449A2 EP00923388A EP00923388A EP1169449A2 EP 1169449 A2 EP1169449 A2 EP 1169449A2 EP 00923388 A EP00923388 A EP 00923388A EP 00923388 A EP00923388 A EP 00923388A EP 1169449 A2 EP1169449 A2 EP 1169449A2
Authority
EP
European Patent Office
Prior art keywords
clasp
polypeptide
sequence
polynucleotide
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00923388A
Other languages
German (de)
English (en)
Inventor
Peter S. Lu
Jonathan David Garman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arbor Vita Corp
Original Assignee
Arbor Vita Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arbor Vita Corp filed Critical Arbor Vita Corp
Publication of EP1169449A2 publication Critical patent/EP1169449A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne une molécule de surface dénommée protéine asymétrique de type cadhérine («Clasp-2»). L'invention concerne en particulier des polynucléotides, des polypeptides, des protéines hybrides et des anticorps de CLASP-2. L'invention concerne en outre des méthodes de modulation d'une réponse immunitaire par perturbation de la fonction de CLASP-2.
EP00923388A 1999-04-14 2000-04-13 Proteines transmembranaires clasp-2 Withdrawn EP1169449A2 (fr)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US12917199P 1999-04-14 1999-04-14
US129171P 1999-04-14
US13411499P 1999-05-14 1999-05-14
US13411899P 1999-05-14 1999-05-14
US13411799P 1999-05-14 1999-05-14
US134114P 1999-05-14
US134117P 1999-05-14
US134118P 1999-05-14
US16086099P 1999-10-21 1999-10-21
US160860P 1999-10-21
US16249899P 1999-10-29 1999-10-29
US162498P 1999-10-29
US17045399P 1999-12-13 1999-12-13
US170453P 1999-12-13
US17619500P 2000-01-14 2000-01-14
US176195P 2000-01-14
US18229600P 2000-02-14 2000-02-14
US182296P 2000-02-14
PCT/US2000/010158 WO2000061747A2 (fr) 1999-04-14 2000-04-13 Proteines transmembranaires clasp-2

Publications (1)

Publication Number Publication Date
EP1169449A2 true EP1169449A2 (fr) 2002-01-09

Family

ID=27578518

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00923388A Withdrawn EP1169449A2 (fr) 1999-04-14 2000-04-13 Proteines transmembranaires clasp-2

Country Status (3)

Country Link
EP (1) EP1169449A2 (fr)
AU (1) AU4352000A (fr)
WO (1) WO2000061747A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002031117A2 (fr) * 2000-10-13 2002-04-18 Arbor Vita Corporation Proteines transmembranaires clasp-2
US20020152493A1 (en) * 2000-12-06 2002-10-17 Allen Keith D. Transgenic mice containing PTP36 tyrosine phosphatase gene disruptions
ATE483976T1 (de) * 2001-06-05 2010-10-15 Exelixis Inc Gfats als modifikatoren des p53-wegs und verwendungsverfahren
AU2003291558B2 (en) * 2001-08-03 2009-08-13 Arbor Vita Corporation Molecular interactions in neurons
BR0314155A (pt) * 2002-09-09 2005-07-05 Arbor Vita Corp Métodos para diagnosticar câncer cervical
CN101287988B (zh) * 2005-07-01 2012-10-10 阿波维塔公司 用于流感诊断和治疗的方法和组合物
CN112986589B (zh) * 2017-01-05 2023-01-24 深圳迈瑞生物医疗电子股份有限公司 网织红细胞模拟粒子、血小板模拟粒子制备方法及质控物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU761425B2 (en) * 1998-10-02 2003-06-05 Board Of Trustees Of The Leland Stanford Junior University Cadherin-like asymmetry protein-1, and methods for its use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0061747A3 *

Also Published As

Publication number Publication date
WO2000061747A2 (fr) 2000-10-19
WO2000061747A9 (fr) 2002-07-11
WO2000061747A3 (fr) 2001-01-11
AU4352000A (en) 2000-11-14

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Legal Events

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Effective date: 20011026

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Effective date: 20040915