WO2000061747A3 - Clasp-2 transmembrane proteins - Google Patents

Clasp-2 transmembrane proteins Download PDF

Info

Publication number
WO2000061747A3
WO2000061747A3 PCT/US2000/010158 US0010158W WO0061747A3 WO 2000061747 A3 WO2000061747 A3 WO 2000061747A3 US 0010158 W US0010158 W US 0010158W WO 0061747 A3 WO0061747 A3 WO 0061747A3
Authority
WO
WIPO (PCT)
Prior art keywords
clasp
relates
transmembrane proteins
polynucleotides
polypeptides
Prior art date
Application number
PCT/US2000/010158
Other languages
French (fr)
Other versions
WO2000061747A9 (en
WO2000061747A2 (en
Inventor
Peter S Lu
Original Assignee
Arbor Vita Corp
Peter S Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arbor Vita Corp, Peter S Lu filed Critical Arbor Vita Corp
Priority to JP2000611670A priority Critical patent/JP2004535751A/en
Priority to AU43520/00A priority patent/AU4352000A/en
Priority to EP00923388A priority patent/EP1169449A2/en
Publication of WO2000061747A2 publication Critical patent/WO2000061747A2/en
Publication of WO2000061747A3 publication Critical patent/WO2000061747A3/en
Publication of WO2000061747A9 publication Critical patent/WO2000061747A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to a cell surface molecule, designated cadherin-like asymmetry protein-2 ('CLASP-2'). In particular, it relates to CLASP-2 polynucleotides, polypeptides, fusion proteins, and antibodies. The invention also relates to methods of modulating an immune response by interfering with CLASP-2 function.
PCT/US2000/010158 1999-04-14 2000-04-13 Clasp-2 transmembrane proteins WO2000061747A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2000611670A JP2004535751A (en) 1999-04-14 2000-04-13 CLASP-2 transmembrane protein
AU43520/00A AU4352000A (en) 1999-04-14 2000-04-13 Clasp-2 transmembrane proteins
EP00923388A EP1169449A2 (en) 1999-04-14 2000-04-13 Clasp-2 transmembrane proteins

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US12917199P 1999-04-14 1999-04-14
US60/129,171 1999-04-14
US13411499P 1999-05-14 1999-05-14
US13411899P 1999-05-14 1999-05-14
US13411799P 1999-05-14 1999-05-14
US60/134,117 1999-05-14
US60/134,118 1999-05-14
US60/134,114 1999-05-14
US16086099P 1999-10-21 1999-10-21
US60/160,860 1999-10-21
US16249899P 1999-10-29 1999-10-29
US60/162,498 1999-10-29
US17045399P 1999-12-13 1999-12-13
US60/170,453 1999-12-13
US17619500P 2000-01-14 2000-01-14
US60/176,195 2000-01-14
US18229600P 2000-02-14 2000-02-14
US60/182,296 2000-02-14

Publications (3)

Publication Number Publication Date
WO2000061747A2 WO2000061747A2 (en) 2000-10-19
WO2000061747A3 true WO2000061747A3 (en) 2001-01-11
WO2000061747A9 WO2000061747A9 (en) 2002-07-11

Family

ID=27578518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/010158 WO2000061747A2 (en) 1999-04-14 2000-04-13 Clasp-2 transmembrane proteins

Country Status (3)

Country Link
EP (1) EP1169449A2 (en)
AU (1) AU4352000A (en)
WO (1) WO2000061747A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002031117A2 (en) * 2000-10-13 2002-04-18 Arbor Vita Corporation Clasp-2 transmembrane proteins
US20020152493A1 (en) * 2000-12-06 2002-10-17 Allen Keith D. Transgenic mice containing PTP36 tyrosine phosphatase gene disruptions
ATE483976T1 (en) * 2001-06-05 2010-10-15 Exelixis Inc GFATS AS P53 PATHWAY MODIFIERS AND METHODS OF USE
AU2003291558B2 (en) * 2001-08-03 2009-08-13 Arbor Vita Corporation Molecular interactions in neurons
EP1537415B1 (en) * 2002-09-09 2008-12-17 Arbor Vita Corporation Methods of diagnosing cervical cancer
US20070014803A1 (en) * 2005-07-01 2007-01-18 Arbor Vita Corporation Methods and compositions for diagnosis and treatment of viral and bacterial infections
CN112986589B (en) * 2017-01-05 2023-01-24 深圳迈瑞生物医疗电子股份有限公司 Reticulocyte mimic particle, platelet mimic particle preparation method and quality control material

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000020434A1 (en) * 1998-10-02 2000-04-13 The Board Of Trustees Of The Leland Stanford Junior University Cadherin-like asymmetry protein-1, and methods for its use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000020434A1 (en) * 1998-10-02 2000-04-13 The Board Of Trustees Of The Leland Stanford Junior University Cadherin-like asymmetry protein-1, and methods for its use

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 11 November 1999 (1999-11-11), L. HILLIER ET AL: "WashU-NCI human EST project", XP002148282 *
DATABASE EMBL 16 December 1999 (1999-12-16), A. POUSTKA ET AL: "Homo sapiens mRNA; EST DKFZp761J19121_r1 ( from clone DKFZp761J19121)", XP002148281 *
DATABASE EMBL 24 September 1994 (1994-09-24), L. PIANESE ET AL: "TRG gene and protein.", XP002148278 *
DATABASE EMBL 4 August 1999 (1999-08-04), R. KIKUNO ET AL: "Homo sapiens mRNA for KIAA1058 protein, partial cds", XP002148280 *
DATABASE EMBL 6 March 2000 (2000-03-06), Z.YE ET AL: "Identification of Iron regulated genes by rescreening cDNA libraries from SSH with antisense probe from three iron conditions", XP002148279 *
L. PIANESE ET AL: "a novel thyroid transcript negatively regulated by TSH.", LIFE SCI. ADV. (MOL. BIOL.), vol. 13, 1994, pages 75 - 83 *
R. KIKUNO ET AL: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequenecs of 100 new cDNA clones from brain which code for large proteins in vitro", DNA RESEARCH, vol. 6, no. 3, 1999, pages 197 - 205, XP000852618 *
UNPUBLISHED *

Also Published As

Publication number Publication date
AU4352000A (en) 2000-11-14
WO2000061747A9 (en) 2002-07-11
WO2000061747A2 (en) 2000-10-19
EP1169449A2 (en) 2002-01-09

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