EP1167757A3 - Pumpe für niedrige Flussraten - Google Patents

Pumpe für niedrige Flussraten Download PDF

Info

Publication number
EP1167757A3
EP1167757A3 EP01114608A EP01114608A EP1167757A3 EP 1167757 A3 EP1167757 A3 EP 1167757A3 EP 01114608 A EP01114608 A EP 01114608A EP 01114608 A EP01114608 A EP 01114608A EP 1167757 A3 EP1167757 A3 EP 1167757A3
Authority
EP
European Patent Office
Prior art keywords
pump
transporting fluid
membrane
low flow
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP01114608A
Other languages
English (en)
French (fr)
Other versions
EP1167757B1 (de
EP1167757A2 (de
Inventor
Carlo Effenhauser
Herbert Harttig
Peter Kraemer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Original Assignee
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Roche Diagnostics GmbH filed Critical F Hoffmann La Roche AG
Publication of EP1167757A2 publication Critical patent/EP1167757A2/de
Publication of EP1167757A3 publication Critical patent/EP1167757A3/de
Application granted granted Critical
Publication of EP1167757B1 publication Critical patent/EP1167757B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/06—Pumps having fluid drive
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Abstract

Die vorliegende Erfindung betrifft eine Pumpe für Flußraten im Bereich von etwa 1 bis 1000nl/min bei der der Flüssigkeitstransport durch eine Verdampfung einer Transportflüssigkeit (3) durch eine benetzbare Membran (4) erfolgt. Insbesondere sind erfindungsgemäße Pumpen für Anwendungen im Bereich der medizinischen Diagnostik wie der Mikrodialyse oder Ultrafiltration geeignet.
EP01114608A 2000-06-21 2001-06-19 Pumpe für niedrige Flussraten Expired - Lifetime EP1167757B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10029453 2000-06-21
DE10029453A DE10029453C2 (de) 2000-06-21 2000-06-21 Pumpe für sehr niedrige Flußraten

Publications (3)

Publication Number Publication Date
EP1167757A2 EP1167757A2 (de) 2002-01-02
EP1167757A3 true EP1167757A3 (de) 2003-07-09
EP1167757B1 EP1167757B1 (de) 2004-10-06

Family

ID=7645800

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01114608A Expired - Lifetime EP1167757B1 (de) 2000-06-21 2001-06-19 Pumpe für niedrige Flussraten

Country Status (5)

Country Link
US (2) US6860993B2 (de)
EP (1) EP1167757B1 (de)
AT (1) ATE278874T1 (de)
DE (2) DE10029453C2 (de)
ES (1) ES2228700T3 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020010406A1 (en) 1996-05-17 2002-01-24 Douglas Joel S. Methods and apparatus for expressing body fluid from an incision
US7235056B2 (en) 1996-05-17 2007-06-26 Amira Medical Body fluid sampling device and methods of use
EP1579814A3 (de) 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Verfahren und Vorrichtung zur Probenahme und Analyse von Körperflüssigkeit
US7828749B2 (en) 1996-05-17 2010-11-09 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
EP1432353A1 (de) * 2001-09-26 2004-06-30 Hoffman-La Roche AG Verfahren und vorrichtung zur entnahme von körperflüssigkeiten
US10502448B1 (en) 2002-01-02 2019-12-10 United States Of America As Represented By The Secretary Of The Air Force Self-clearing vents based on droplet expulsion
US8679233B1 (en) * 2002-01-02 2014-03-25 The United States Of America As Represented By The Secretary Of The Air Force Modification of the degree of liquid contact with a solid by control of surface and micro-channel capillary geometry
DE10222228A1 (de) * 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Mikropumpe mit Heizelementen für einen pulsierten Betrieb
EP1475113A1 (de) * 2003-05-08 2004-11-10 Novo Nordisk A/S Externer Nadeleinsetzer
EP1624914B1 (de) * 2003-05-08 2008-04-16 Novo Nordisk A/S Interne nadeleinführvorrichtung
ATE474611T1 (de) * 2003-05-08 2010-08-15 Novo Nordisk As Eine auf die haut aufbringbare injektionsvorrichtung mit abtrennbarem betätigungsteil zum einführen der nadel
EP1502613A1 (de) * 2003-08-01 2005-02-02 Novo Nordisk A/S Gerät mit Rückziehvorrichting für eine Nadel
KR20060099520A (ko) * 2003-10-21 2006-09-19 노보 노르디스크 에이/에스 의료용 피부 장착 장치
WO2005094920A1 (en) * 2004-03-30 2005-10-13 Novo Nordisk A/S Actuator system comprising lever mechanism
DE102004022678A1 (de) 2004-05-05 2005-12-15 Humboldt-Universität Zu Berlin Verfahren zum Regeln eines Volumenflusses einer Flüssigkeit in einer osmotischen Mikropumpe und osmotische Mikropumpe
DE102004039404B4 (de) * 2004-08-13 2007-01-25 Humboldt-Universität Zu Berlin Verfahren zum regelbaren Pumpen einer Flüssigkeit und Mikropumpe für die Mikrofluidik
DE102004042578A1 (de) * 2004-09-02 2006-03-23 Roche Diagnostics Gmbh Mikropumpe zur Förderung von Flüssigkeiten mit niedrigen Förderraten im Druck/Saug-Betrieb
DE102004042987A1 (de) * 2004-09-06 2006-03-23 Roche Diagnostics Gmbh Push-Pull betriebene Pumpe für ein mikrofluidisches System
US20090012472A1 (en) * 2004-09-22 2009-01-08 Novo Nordisk A/S Medical Device with Cannula Inserter
US20080215006A1 (en) * 2004-09-22 2008-09-04 Novo Nordisk A/S Medical Device with Transcutaneous Cannula Device
CN100579598C (zh) * 2004-12-06 2010-01-13 诺和诺德公司 透气的皮肤可安装设备
CN100571800C (zh) 2005-01-24 2009-12-23 诺和诺德公司 具有被保护的经皮设备的医疗设备
CN101175516B (zh) * 2005-05-13 2011-02-16 诺和诺德公司 适于检测经皮装置脱离的医疗装置
US8197231B2 (en) 2005-07-13 2012-06-12 Purity Solutions Llc Diaphragm pump and related methods
WO2007039300A1 (en) * 2005-10-06 2007-04-12 Rhodia Operations Microfluidic evaporators and process for determining physical and/or chemical properties of chemical compounds or mixtures of chemical compounds
US20090062778A1 (en) * 2006-03-13 2009-03-05 Novo Nordisk A/S Medical System Comprising Dual-Purpose Communication Means
JP2009530880A (ja) * 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー／エス 複合通信手段を使用した電子装置の安全なペアリング
WO2007122207A1 (en) * 2006-04-26 2007-11-01 Novo Nordisk A/S Skin-mountable device in packaging comprising coated seal member
CN101460207B (zh) * 2006-06-06 2012-03-21 诺沃-诺迪斯克有限公司 包括皮肤可安装设备及其包装件的组件
IL180877A (en) * 2007-01-22 2011-09-27 Mfs Medical Flow Systems Ltd Improved flow regulator
WO2008107467A1 (en) * 2007-03-06 2008-09-12 Novo Nordisk A/S Pump assembly comprising actuator system
US8557179B2 (en) * 2007-10-31 2013-10-15 Novo Nordisk A/S Non-porous material as sterilization barrier
US7526917B1 (en) * 2008-08-11 2009-05-05 Hoffman John C Gas diffusion vacuum device
FR2967915B1 (fr) * 2010-11-26 2014-05-16 Commissariat Energie Atomique Dispositif d'evaporation
US11485968B2 (en) 2012-02-13 2022-11-01 Neumodx Molecular, Inc. Microfluidic cartridge for processing and detecting nucleic acids
AU2013221701B2 (en) 2012-02-13 2017-02-02 Molecular Systems Corporation Microfluidic cartridge for processing and detecting nucleic acids
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US11648561B2 (en) 2012-02-13 2023-05-16 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9610392B2 (en) 2012-06-08 2017-04-04 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
DK2912174T3 (da) 2012-10-25 2019-08-26 Neumodx Molecular Inc Fremgangsmåde og materialer til isolering af nukleinsyrematerialer
US20220280681A1 (en) 2019-09-25 2022-09-08 3M Innovative Properties Company Wound dressing material and methods of making and using the same
WO2021084354A1 (en) 2019-10-28 2021-05-06 3M Innovative Properties Company Wound dressing material and methods of making and using the same
US20240115427A1 (en) 2021-02-01 2024-04-11 3M Innovative Properties Company Reinforced fiber web and wound dressing material including the same

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2208324A (en) * 1987-07-24 1989-03-22 Amersham Int Plc Controlled flow rate capillary suction pump
US4832034A (en) * 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
WO1995010221A2 (en) * 1993-10-09 1995-04-20 Jakob Korf Monitoring the concentration of a substance or a group of substances in a body fluid
US5938928A (en) * 1991-08-01 1999-08-17 Nonap Pty. Ltd. Osmotic distillation process using a membrane laminate
US6039792A (en) * 1997-06-24 2000-03-21 Regents Of The University Of California And Bp Amoco Corporation Methods of forming and using porous structures for energy efficient separation of light gases by capillary condensation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1245567A (en) * 1983-09-16 1988-11-29 Michio Inoue Hollow-fiber filtering module and water purification device utilizing it
US5045202A (en) * 1985-11-18 1991-09-03 Stearns Donald M Centrifugal oxygenator for treatment of waste water and system
US4976866A (en) * 1989-04-03 1990-12-11 The Dow Chemical Company Concentric tubular membrane device and process useful in ion exchange or absorbent processes
IT1241940B (it) * 1989-11-09 1994-02-01 Grace W R & Co Dispositivo di multiconcentrazione di liquidi a perdere.
US5552046A (en) * 1995-01-23 1996-09-03 Johnston; Arthur W. Multi-stage microbiological water filter
US5693230A (en) * 1996-01-25 1997-12-02 Gas Research Institute Hollow fiber contactor and process
US6136189A (en) * 1998-01-20 2000-10-24 Innova Pure Water Inc. Enhanced in-bottle filtration mechanism and techniques
JP2001269572A (ja) * 2000-03-28 2001-10-02 Forestry & Forest Products Research Inst Forestry Agency 無機質多孔粒体の再生方法及び水の浄化方法並びに水の連続浄化装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4832034A (en) * 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
GB2208324A (en) * 1987-07-24 1989-03-22 Amersham Int Plc Controlled flow rate capillary suction pump
US5938928A (en) * 1991-08-01 1999-08-17 Nonap Pty. Ltd. Osmotic distillation process using a membrane laminate
WO1995010221A2 (en) * 1993-10-09 1995-04-20 Jakob Korf Monitoring the concentration of a substance or a group of substances in a body fluid
US6039792A (en) * 1997-06-24 2000-03-21 Regents Of The University Of California And Bp Amoco Corporation Methods of forming and using porous structures for energy efficient separation of light gases by capillary condensation

Also Published As

Publication number Publication date
DE10029453A1 (de) 2002-01-10
ATE278874T1 (de) 2004-10-15
US20020087110A1 (en) 2002-07-04
EP1167757B1 (de) 2004-10-06
US6860993B2 (en) 2005-03-01
EP1167757A2 (de) 2002-01-02
ES2228700T3 (es) 2005-04-16
DE50103943D1 (de) 2004-11-11
DE10029453C2 (de) 2002-06-13
US6872315B2 (en) 2005-03-29
US20050006309A1 (en) 2005-01-13

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