EP1158897B1 - Procede pour determiner la capacite de charge d'un etre humain - Google Patents
Procede pour determiner la capacite de charge d'un etre humain Download PDFInfo
- Publication number
- EP1158897B1 EP1158897B1 EP00916909A EP00916909A EP1158897B1 EP 1158897 B1 EP1158897 B1 EP 1158897B1 EP 00916909 A EP00916909 A EP 00916909A EP 00916909 A EP00916909 A EP 00916909A EP 1158897 B1 EP1158897 B1 EP 1158897B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- lactate
- measured
- sub
- anaerobic threshold
- time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/22—Ergometry; Measuring muscular strength or the force of a muscular blow
- A61B5/221—Ergometry, e.g. by using bicycle type apparatus
- A61B5/222—Ergometry, e.g. by using bicycle type apparatus combined with detection or measurement of physiological parameters, e.g. heart rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/92—Computer assisted medical diagnostics
Definitions
- the invention relates to methods for determining the load capacity of a People considering the individual anaerobic threshold by non-invasive measurement of lactate concentrations depending on work done.
- lactate concentration of the blood plasma becomes predominant in the loading phase determined by the lactate influx, d. H. due to the predominantly diffusive lactate flow from muscle to blood plasma. This influx is driven by the load occurring concentration gradient between lactate producing muscle tissue and Blood plasma.
- lactate efflux predominates, d. H. the lactate elimination from the blood plasma.
- the so-called individual anaerobic threshold be determined, which is a fixed, uniquely reproducible value is.
- the "individual anaerobic threshold” is also for physiological parameters like assessment of physical performance, exercise blood pressure and coronary heart disease of importance.
- the individual anaerobic threshold is determined by lactic acid determination in the Blood, the changes of the lactic acid portion depending on the work done per unit of time is measured.
- the individual anaerobic threshold according to Stegmann can not only be determined by continuous lactate measurement from human blood, but also from the respiratory measurements of the respiratory minute volume, the O 2 content of the respiratory minute volume and the CO 2 content of the respiratory minute volume determine (EP 0 742 693 B1).
- the present invention is based on the problem, a method of the above so-called type so that there is the possibility of the lactate concentration change to gain more characteristic data for humans.
- Will the slope of the Lactate concentration-time curve, also called lactate accumulation rate is, upon reaching the individual anaerobic threshold (IAT) by the state of a Organism characterized in which a continuous load with that of the individual anaerobic threshold corresponding achievement does not lead to a growing increase, but to a suspension of the lactate concentration-time curve at the maximum level leads, then is, if the individual anaerobic threshold corresponding Performance is exceeded, a rapid increase in lactate concentration in the blood plasma determine.
- the change in the lactate concentration measured as a function of the time load can be a stationary bike or for example a treadmill or a other device or an arrangement are used, which also in the determination of individual anaerobic threshold (IAT).
- the devices are over Lines connected to a data processing system, so the per unit time to determine the work done. Furthermore, there is a time-dependent review of Blood of man.
- the corresponding blur values, i. their for the lactate concentration Characteristic values such as lactic acid content of the data processing system also supplied.
- the data processing system calculates a measurement curve, in accordance with FIG. 1, the concentration C of lactate in mmol compared the time t is preferably plotted in minutes.
- the corresponding trace is provided in Fig. 1 with the reference numeral 22.
- the load increase can be stepped (curve 24) or continuously (curve 26). In that regard, however, is sufficient referenced measuring methods.
- the change in concentration of the lactate is determined not only up to the anaerobic individual threshold IAT, ie beyond the continuous load limit, but also under greater load, in which a rapid increase in the lactate concentration in the blood plasma is detectable.
- a stepwise (FIG. 2) or continuous load increase (FIG. 3) ie in an analogous manner, as is known from the determination of the individual threshold IAT.
- the gradients are then the lactate concentration time curve in each of the individual anaerobic threshold IAT t corresponding time IAT as determined in other times such as t x> t IAT, and optionally up to the load end of t E of the trace 22nd
- the corresponding gradients can be evaluated as a lactate accumulation rate, it being apparent that the lactate accumulation rates increase above the time t IAT , ie the slope tan ⁇ IAT at a time t IAT is less than the slope tan ⁇ x at a time t x > t IAT which in turn is smaller than the slope t ⁇ E at a time t E at the end of loading.
- Characteristic reproducible values of the burdened human can then be obtained from the lactate performance curve 22 above the individual anaerobic threshold IAT if the lactate accumulation rate is adjusted by the individual anaerobic threshold, ie the difference ⁇ A between the slope tan ⁇ x and the slope tan ⁇ IAT is formed. This difference is a measure of the systemic disturbance of the lactate concentration above the continuous load corresponding to the individual anaerobic threshold and thus individually characteristic of the individual.
- the performance or resilience of humans can be seen both from the Fig. 1 to be taken lactate power curve and a characteristic curve 28 taken where the change in lactate accumulation rate is ⁇ A versus power L is applied.
- the characteristic curve 28 can with a standard curve 30, with a curve recorded by the same person at another time or with be compared to another people's trajectory, thus providing statements about the To derive performance and / or load capacity and possibly normalized values.
- FIG. 4 shows the correlation between different powers L 1 x and L 2 x , which are provided in the exercise test for the same lactate accumulation rate ⁇ A adjusted by the individual aerobic threshold.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Investigating Strength Of Materials By Application Of Mechanical Stress (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Claims (5)
- Procédé pour déterminer la résistance d'un individu en tenant compte du seuil anaérobie individuel par mesure non traumatique des concentrations de lactate en fonction du travail fourni, comprenant les étapes suivantes :mesure de la modification de la concentration de lactate en fonction du temps, au-delà du seuil anaérobie,adaptation d'une courbe de mesure aux valeurs mesurées ainsi acquises, dans laquelle la concentration de lactate est portée par rapport au temps,détermination d'une première pente de la courbe de mesure dans un instant tIAt correspondant au seuil anaérobie individuel,détermination d'au moins une autre pente sur la courbe de mesure à instant tx, sachant que tx > tIAt etsoustraction de la deuxième pente de la première pente pour déterminer une différence ΔA.
- Procédé selon la revendication 1,
caractérisé en ce
que des différences ΔAx avec x = 1, 2, ... sont portées en fonction du travail, et que les courbes de mesure ainsi formées sont comparées avec des courbes de mesure normées, des courbes de mesure de différents individus ou des courbes de mesure du même individus pour différents temps d'effort. - Procédé selon la revendication 1 ou 2,
caractérisé en ce que les courbes de mesure sont mesurées lors d'une modification par paliers du travail de l'individu. - Procédé selon la revendication 1 ou 2,
caractérisé en ce que les courbes de mesure sont mesurées lors d'une modification continue du travail de l'individu. - Procédé selon l'une de revendications précédentes,
caractérisé en ce qu'on utilise comme seuil anaérobie individuel le seuil défini selon Stegmann comme paramètre de soustraction pour déterminer la différence ΔA.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19909852 | 1999-03-08 | ||
DE19909852A DE19909852A1 (de) | 1999-03-08 | 1999-03-08 | Verfahren zur Bestimmung der Belastbarkeit eines Menschen |
PCT/EP2000/002030 WO2000053091A1 (fr) | 1999-03-08 | 2000-03-08 | Procede pour determiner la capacite de charge d'un etre humain |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1158897A1 EP1158897A1 (fr) | 2001-12-05 |
EP1158897B1 true EP1158897B1 (fr) | 2005-01-26 |
Family
ID=7899908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00916909A Expired - Lifetime EP1158897B1 (fr) | 1999-03-08 | 2000-03-08 | Procede pour determiner la capacite de charge d'un etre humain |
Country Status (6)
Country | Link |
---|---|
US (1) | US6899676B1 (fr) |
EP (1) | EP1158897B1 (fr) |
AT (1) | ATE287663T1 (fr) |
AU (1) | AU3809400A (fr) |
DE (2) | DE19909852A1 (fr) |
WO (1) | WO2000053091A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10324904B4 (de) * | 2003-05-30 | 2013-03-07 | Siemens Aktiengesellschaft | Vorrichtung zur Trainingseinstellung im Sport, insbesondere im Laufsport |
DE10333075B4 (de) * | 2003-07-21 | 2011-06-16 | Siemens Ag | Verfahren und Vorrichtung zur Trainingseinstellung im Sport, insbesondere im Laufsport |
DE102004052083A1 (de) * | 2004-10-26 | 2006-05-04 | Nuske, Andreas | Digitales, elektronisches Diagnose-Verfahren zur unblutigen Lactat-Leistungsbestimmung und einer mobilen Messvorrichtung zur elektronischen Durchführung |
DE102007052776B4 (de) * | 2007-11-02 | 2011-02-24 | Jerichow, Ulrich, Dr. | Verfahren zur Steuerung und/oder Regelung einer Trainings und/oder Rehabilitationseinheit |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4622980A (en) * | 1984-11-01 | 1986-11-18 | Horst E. Kunig | Method and apparatus for determining of stress condition of a subject |
DE4406286A1 (de) * | 1994-02-26 | 1995-08-31 | Stegmann Heiner Dr Med | Verfahren zur Bestimmung der individuellen anaeroben Schwelle eines Menschens |
AT407950B (de) * | 1999-05-25 | 2001-07-25 | Hoffmann La Roche | Verfahren und vorrichtung zur ermittlung eines von respiratorischen messdaten abhängigen indikators |
-
1999
- 1999-03-08 DE DE19909852A patent/DE19909852A1/de not_active Withdrawn
-
2000
- 2000-03-08 EP EP00916909A patent/EP1158897B1/fr not_active Expired - Lifetime
- 2000-03-08 US US09/926,129 patent/US6899676B1/en not_active Expired - Lifetime
- 2000-03-08 AU AU38094/00A patent/AU3809400A/en not_active Abandoned
- 2000-03-08 AT AT00916909T patent/ATE287663T1/de not_active IP Right Cessation
- 2000-03-08 WO PCT/EP2000/002030 patent/WO2000053091A1/fr active IP Right Grant
- 2000-03-08 DE DE50009357T patent/DE50009357D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1158897A1 (fr) | 2001-12-05 |
DE19909852A1 (de) | 2000-09-14 |
AU3809400A (en) | 2000-09-28 |
ATE287663T1 (de) | 2005-02-15 |
DE50009357D1 (de) | 2005-03-03 |
WO2000053091A1 (fr) | 2000-09-14 |
US6899676B1 (en) | 2005-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69532803T2 (de) | Verfahren und vorrichtung zum bestimmen des grades der anstrengung von fitness - und athletik-geräten und zur anzeige der beanspruchung beim training | |
DE102004025895B4 (de) | Müdigkeitsniveau-Erfassungsvorrichtung | |
DE60123693T2 (de) | Ermittlung des Stressniveaus bei Fitnessübung | |
DE69723400T2 (de) | System zur Anzeige von Änderungen der Körperlage | |
DE60115736T2 (de) | Messung bezüglich des menschlichen Energiestoffwechsels | |
DE60203246T2 (de) | Aktive implantierbare medizinische Vorrichtung mit verbesserten Mitteln zum Unterscheiden zwischen den Phasen von Wachzustand und Schlafzustand | |
DE602004000513T2 (de) | System zur Spektroskopieanalyse von Blutkomponenten und zum Beseitigen von abnormalen Daten | |
DE4338958C2 (de) | Verfahren zum Festlegen einer für das Einhalten einer Sollpulszahl optimalen Leistung | |
DE60124689T2 (de) | Überwachung eines Patientenzustandes unter Anästhesie oder Sedierung | |
DE102007025664B4 (de) | Verfahren zur automatischen Registrierung der physischen Leistungsfähigkeit eines Probanden | |
EP2413788A1 (fr) | Procédé et dispositif destinés à déterminer la forme physique générale d'un sujet de test | |
DE102006039957B4 (de) | Verfahren zur Auswertung der Herzratenvariabilität | |
DE69725622T2 (de) | Verfahren für das harmonische filtern von daten | |
DE112017004579T5 (de) | Blutdruckmessgerät, Verfahren zum Steuern des Blutdruckmessgerätes und Programm | |
EP0742693B1 (fr) | Determination de la valeur limite individuelle d'anaerobiose | |
EP1158897B1 (fr) | Procede pour determiner la capacite de charge d'un etre humain | |
EP2120691B1 (fr) | Procede de determination de l'intensite d'entrainement | |
EP1673009A1 (fr) | Procede et appareil de mesure de la pression arterielle | |
WO2014060182A1 (fr) | Dispositif et procédé pour détecter et signaler un état de tension d'une personne | |
DE102007054358B4 (de) | Vorrichtung zur Ganganalyse zu Trainings- oder Rehabilitationszwecken | |
WO2016142246A2 (fr) | Procédé pour la saisie successive de paires de données et/ou pour la détermination d'au moins une caractéristique, unité d'évaluation de données, dispositif, support d'enregistrement digital, produit programme informatique et programme informatique | |
EP1417926A1 (fr) | Méthode et appareil pour l'enrégistrement non-invasif du debit sanguin et pour l'enrégistrement et le traitement des signaux ECG et usage d'un appareil ECG | |
WO2011060782A1 (fr) | Procédé non invasif et dispositif pour déterminer des limites seuils de charge notamment lors d'activité sportive | |
EP0359972B1 (fr) | Dispositif pour la détermination non intrusive de paramètres d'écoulement dans les extrémités humaines | |
DE19781642B4 (de) | Verfahren zum Bestimmen eines die maximale Sauerstoffaufnahme beschreibenden Wertes eines zu beurteilenden Lebenswesens |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20011004 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20031230 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT;WARNING: LAPSES OF ITALIAN PATENTS WITH EFFECTIVE DATE BEFORE 2007 MAY HAVE OCCURRED AT ANY TIME BEFORE 2007. THE CORRECT EFFECTIVE DATE MAY BE DIFFERENT FROM THE ONE RECORDED. Effective date: 20050126 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050126 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050126 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D Free format text: GERMAN |
|
REF | Corresponds to: |
Ref document number: 50009357 Country of ref document: DE Date of ref document: 20050303 Kind code of ref document: P |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050308 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050331 Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050331 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050426 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050426 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050426 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20050507 |
|
GBT | Gb: translation of ep patent filed (gb section 77(6)(a)/1977) |
Effective date: 20050518 |
|
NLV1 | Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act | ||
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: LUCHS & PARTNER PATENTANWAELTE |
|
BERE | Be: lapsed |
Owner name: STEGMANN, HEINER Effective date: 20050331 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20051027 |
|
ET | Fr: translation filed | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: AT Payment date: 20060329 Year of fee payment: 7 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IE Payment date: 20070412 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: LU Payment date: 20070417 Year of fee payment: 8 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070308 |
|
BERE | Be: lapsed |
Owner name: STEGMANN, HEINER Effective date: 20050331 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050626 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20080423 Year of fee payment: 9 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080310 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20090324 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20090331 Year of fee payment: 10 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090331 Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090331 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080308 |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20100308 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20101130 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100331 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100308 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20190327 Year of fee payment: 20 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 50009357 Country of ref document: DE |