EP1123501A4 - Verfahren zur konzentration von mikroorganismen mittels affinitätstrennung - Google Patents

Verfahren zur konzentration von mikroorganismen mittels affinitätstrennung

Info

Publication number
EP1123501A4
EP1123501A4 EP99943648A EP99943648A EP1123501A4 EP 1123501 A4 EP1123501 A4 EP 1123501A4 EP 99943648 A EP99943648 A EP 99943648A EP 99943648 A EP99943648 A EP 99943648A EP 1123501 A4 EP1123501 A4 EP 1123501A4
Authority
EP
European Patent Office
Prior art keywords
methods
affinity separation
concentrating microorganisms
concentrating
microorganisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99943648A
Other languages
English (en)
French (fr)
Other versions
EP1123501A1 (de
Inventor
Daniel L Siegel
Anthony Saunders
Oded Shoseyov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CBD Technologies Ltd
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
CBD Technologies Ltd
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CBD Technologies Ltd, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical CBD Technologies Ltd
Publication of EP1123501A1 publication Critical patent/EP1123501A1/de
Publication of EP1123501A4 publication Critical patent/EP1123501A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP99943648A 1998-10-19 1999-08-04 Verfahren zur konzentration von mikroorganismen mittels affinitätstrennung Withdrawn EP1123501A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17504098A 1998-10-19 1998-10-19
US175040 1998-10-19
US30145199A 1999-04-29 1999-04-29
US301451 1999-04-29
PCT/US1999/017589 WO2000023792A1 (en) 1998-10-19 1999-08-04 Methods of concentrating microorganisms using affinity separation

Publications (2)

Publication Number Publication Date
EP1123501A1 EP1123501A1 (de) 2001-08-16
EP1123501A4 true EP1123501A4 (de) 2005-04-13

Family

ID=26870805

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99943648A Withdrawn EP1123501A4 (de) 1998-10-19 1999-08-04 Verfahren zur konzentration von mikroorganismen mittels affinitätstrennung

Country Status (4)

Country Link
EP (1) EP1123501A4 (de)
AU (1) AU5670299A (de)
CA (1) CA2347004A1 (de)
WO (1) WO2000023792A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1320631A (zh) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 一种新的多肽——人含纤维素结合结构域的蛋白10和编码这种多肽的多核苷酸
GB0010910D0 (en) * 2000-05-05 2000-06-28 Jones Osborn Analytical method and apparatus
CN102353779B (zh) * 2001-02-05 2014-10-15 米利波尔公司 微生物的检测
EP1253203A1 (de) 2001-04-25 2002-10-30 Becton Dickinson and Company Schnelles Keimen, Wachstum, Immobilisierung und Detektion von Mikroorganismen
GB0112428D0 (en) * 2001-05-22 2001-07-11 Secr Defence Brit Identifying micro-organisms
US20030022358A1 (en) * 2001-05-29 2003-01-30 Hall Jane H. Growth of filterable organisms that require non-diffusable media components
DE10129815A1 (de) * 2001-06-24 2003-01-09 Profos Ag Verfahren zur Aufreinigung von Bakterienzellen und Zellbestandteilen
US7569025B2 (en) 2002-04-02 2009-08-04 Scantibodies Laboratory, Inc. Methods and devices for treating severe peripheral bacterial infections
GB2387130A (en) 2002-04-04 2003-10-08 Fluid Technologies Plc Hollow fibre filter membrane unit with microorganism detector, and associated usage
EP1909833A2 (de) * 2005-06-20 2008-04-16 Scantibodies Laboratory, Inc. Verfahren und vorrichtungen zur entfernungvon pathogenen und schädlichen substanzen aus körperflüssigkeiten
MX2008007716A (es) 2005-12-13 2008-09-26 Exthera Ab Metodo para eliminar extra corporalmente de la sangre un microbio patogeno, una celula inflamatoria o una proteina inflamatoria.
US8710179B2 (en) 2006-12-14 2014-04-29 Technion Research & Development Foundation Limited Compositions and methods for concentrating and depleting microorganisms
CN101215598B (zh) * 2008-01-11 2010-11-17 中华人民共和国吉林出入境检验检疫局 免疫富集丝检测细菌的方法及免疫富集刷
JP5727383B2 (ja) * 2008-12-31 2015-06-03 スリーエム イノベイティブ プロパティズ カンパニー 大腸菌群の検出プロセス及びこのプロセスで使用するためのキット
BRPI0918693A2 (pt) 2008-12-31 2016-07-26 3M Innovative Properties Co dispositivos para amostragem e métodos para concentração de microorganismos
CN106178161B (zh) 2009-12-01 2020-12-22 艾克塞拉医疗公司 使用固定于表面的多糖从血液中去除细胞因子的方法
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
WO2013130875A1 (en) * 2012-02-29 2013-09-06 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
WO2013188073A1 (en) 2012-06-13 2013-12-19 Exthera Medical, Llc Use of heparin and carbohydrates to treat cancer
BR112015032134B1 (pt) 2013-06-24 2022-05-10 Exthera Medical Corporation Método de ligação em ponto de extremidade de uma manose não redutora a um substrato e esfera possuindo uma manose ligada em ponto de extremidade
EP3065796B1 (de) 2013-11-08 2020-04-15 ExThera Medical Corporation Verfahren zur diagnose von infektionskrankheiten unter verwendung von adsorptionsmedien
DE15782250T1 (de) 2014-04-24 2017-08-10 Exthera Medical Corporation Verfahren zur Entfernung von Bakterien aus Blut unter Verwendung einer hohen Durchflussrate
KR20170060062A (ko) 2014-09-22 2017-05-31 엑스테라 메디컬 코퍼레이션 웨어러블 혈액관류 장치
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
WO2017151797A1 (en) 2016-03-02 2017-09-08 Exthera Medical Corporation Method for treating drug intoxication
FR3056294B1 (fr) * 2016-09-20 2020-02-14 Kabcyt Dispositif de capture de particules biologiques
BR112021021141A2 (pt) 2019-05-16 2021-12-14 Exthera Medical Corp Método para modular estrutura glicocalyx endotelial
CN119318642B (zh) * 2024-12-19 2025-03-07 深圳万可森生物科技有限公司 纳米淀粉颗粒载药系统及在防治水产动物病害中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2825636A1 (de) * 1978-06-12 1979-12-20 Boehringer Mannheim Gmbh Vorrichtung fuer mikrobiologische arbeiten
US4563418A (en) * 1982-04-09 1986-01-07 Bio-Controls Systems, Inc. Process for detection of selected motile organisms
US5415997A (en) * 1987-07-28 1995-05-16 Biotechnology Australia Pty Limited Method for detecting low levels of microorganisms
JPH04228097A (ja) * 1990-07-02 1992-08-18 Toyo Ink Mfg Co Ltd ミルク試料からの細胞分離および濃縮方法とそのキット
US5232838A (en) * 1991-12-09 1993-08-03 Minnesota Mining And Manufacturing Company Culture media device and method of use
US5314855A (en) * 1992-11-09 1994-05-24 Akzo N.V. Adsorbent compositions and methods of manufacture
US5496934A (en) * 1993-04-14 1996-03-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acids encoding a cellulose binding domain
JP3866762B2 (ja) * 1993-11-29 2007-01-10 ジェン−プローブ・インコーポレイテッド 広範な生物からの核酸抽出法
US5681712A (en) * 1995-06-02 1997-10-28 Minnesota Mining And Manufacturing Company Surface colony counting device and method of use
US5807694A (en) * 1995-09-07 1998-09-15 Economic Innovation And Technology Council, University Of Manitoba Detection of salmonella enteritidis and other pathogenic microorganisms and monoclonal antibody useful therefor
US5612473A (en) * 1996-01-16 1997-03-18 Gull Laboratories Methods, kits and solutions for preparing sample material for nucleic acid amplification
US5820767A (en) * 1996-07-29 1998-10-13 Pall Corporation Method for quantitation of microorganism contamination of liquids

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
FRANCISCO J A ET AL: "SPECIFIC ADHESION AND HYDROLYSIS OF CELLULOSE BY INTACT ESCHERICHIACOLI EXPRESSING SURFACE ANCHORED CELLULASE OR CELLULOSE BINDING DOMAINS", BIO/TECHNOLOGY, NATURE PUBLISHING, NEW YORK, NY, US, vol. 11, April 1993 (1993-04-01), pages 491 - 496, XP002947290, ISSN: 0733-222X *
LINDER M ET AL: "The roles and function of cellulose-binding domains", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 57, no. 1-3, 16 September 1997 (1997-09-16), pages 15 - 28, XP004097727, ISSN: 0168-1656 *
See also references of WO0023792A1 *
TOMME P ET AL: "Characterization and affinity applications of cellulose-binding domains", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL SCIENCES & APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 715, no. 1, 11 September 1998 (1998-09-11), pages 283 - 296, XP004147002, ISSN: 1570-0232 *
WIERZBA ANDREW ET AL: "Production and Properties of a Bifunctional Fusion Protein that Mediates Attachment of Vero Cells to Cellulosic Matrices", BIOTECHNOLOGY AND BIOENGINEERING, vol. 47, no. 2, 1995, pages 147 - 154, XP002307744, ISSN: 0006-3592 *

Also Published As

Publication number Publication date
CA2347004A1 (en) 2000-04-27
AU5670299A (en) 2000-05-08
WO2000023792A1 (en) 2000-04-27
EP1123501A1 (de) 2001-08-16

Similar Documents

Publication Publication Date Title
EP1123501A4 (de) Verfahren zur konzentration von mikroorganismen mittels affinitätstrennung
PL342186A1 (en) Improved separating methods
PL342187A1 (en) Improved separating methods
EP0880544A4 (de) Oberflächenmodifizierte affinitätstrennmembran
EP1062365A4 (de) Nachweis von fermentation-verwandten mikroorganismen
AU6884898A (en) Water separation process
ZA97628B (en) Membrane separation process
EP0927353A4 (de) Nachweis von mikroorganismen
GB9806293D0 (en) Separation of air
AUPP790698A0 (en) Separation of microorganisms
GB9827604D0 (en) Methods of immunosuppression
GB9625400D0 (en) Culture of micro-organisms
CZ1495A3 (en) Method of adsorptive separation
AUPP385598A0 (en) Purification of antibodies
GB2319246B (en) Separation process
AU5486099A (en) Recovery of sublethally-injured microorganisms
GB9807833D0 (en) Separation of air
GB9912140D0 (en) Pollutant separation
GB9716710D0 (en) Dielectrophoresis
EP1117476A4 (de) Verfahren und vorrichtung zur aufkonzentration ausgewählter gruppen von mikroorganismen
GB9606063D0 (en) Bicycle suspension
GB9621751D0 (en) Method of separation
AU2882597A (en) Separation of minerals
AU1553201A (en) Method of separation and purification
GB9401122D0 (en) Methods of analysis/separation

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010426

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12M 1/12 B

Ipc: 7B 01D 25/00 B

Ipc: 7C 12Q 1/68 B

Ipc: 7G 01N 33/569 B

Ipc: 7C 12N 1/02 A

A4 Supplementary search report drawn up and despatched

Effective date: 20050225

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050301