EP1092147A1 - Durchflusskontrolle und materialien für mikrovorrichtungen - Google Patents

Durchflusskontrolle und materialien für mikrovorrichtungen

Info

Publication number
EP1092147A1
EP1092147A1 EP99927515A EP99927515A EP1092147A1 EP 1092147 A1 EP1092147 A1 EP 1092147A1 EP 99927515 A EP99927515 A EP 99927515A EP 99927515 A EP99927515 A EP 99927515A EP 1092147 A1 EP1092147 A1 EP 1092147A1
Authority
EP
European Patent Office
Prior art keywords
fluid pathway
constrained
sample
fluid
channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99927515A
Other languages
English (en)
French (fr)
Inventor
Mark A. Hayes
Nolan A. Polson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arizona Board of Regents of University of Arizona
University of Arizona
Original Assignee
Arizona Board of Regents of University of Arizona
University of Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arizona Board of Regents of University of Arizona, University of Arizona filed Critical Arizona Board of Regents of University of Arizona
Publication of EP1092147A1 publication Critical patent/EP1092147A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories

Definitions

  • the present invention provides an analytical device, either microchip- or capillary-based, having the means to exclude specific sample components of interest from a capillary or channel for the purpose of preconcentration or control of movement of sample components.
  • a control system includes a means for controlling the flow of the fluid in the channel and the placement of an electrode at the immediate entrance of each channel on such devices so that material may be directly manipulated by either or both of the effects of both bulk flow and electrically driven migration.
  • Capillary zone electrophoresis is an efficient analytical separation technique which utilizes differences in mobility of sample components in an electric field based on the electrical charge and molecular site and shape of the sample component.
  • Conventional CZE systems typically comprise a buffer- filled capillary with outlet and inlet ends disposed in two reservoirs into which one sample is injected, a means for applying voltage to the capillary resulting in migration of the sample through the capillary, and a means for detecting the sample zone.
  • Figure 5 is a graph showing the normalized fluorescence intensity versus distance outside the capillary entrance for two control experiments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP99927515A 1998-06-11 1999-06-11 Durchflusskontrolle und materialien für mikrovorrichtungen Withdrawn EP1092147A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8895698P 1998-06-11 1998-06-11
US88956P 1998-06-11
PCT/US1999/013340 WO1999064851A1 (en) 1998-06-11 1999-06-11 Control of flow and materials for micro devices

Publications (1)

Publication Number Publication Date
EP1092147A1 true EP1092147A1 (de) 2001-04-18

Family

ID=22214492

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99927515A Withdrawn EP1092147A1 (de) 1998-06-11 1999-06-11 Durchflusskontrolle und materialien für mikrovorrichtungen

Country Status (4)

Country Link
EP (1) EP1092147A1 (de)
JP (1) JP2002517751A (de)
CA (1) CA2328400A1 (de)
WO (1) WO1999064851A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2477287A (en) * 2010-01-27 2011-08-03 Izon Science Ltd Control of particle flow in an aperture

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004009231A1 (ja) 2002-07-18 2004-01-29 National Institute Of Advanced Industrial Science And Technology マイクロ反応装置の製造方法およびマイクロ反応装置
US11090660B2 (en) 2016-08-10 2021-08-17 Arizona Board Of Regents On Behalf Of Arizona State University Hyper efficient separations device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453382A (en) * 1991-08-05 1995-09-26 Indiana University Foundation Electrochromatographic preconcentration method
US5200050A (en) * 1991-10-25 1993-04-06 Washington State University Research Foundation Electrophoretic processor and methods
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
AU710548B2 (en) * 1995-03-03 1999-09-23 Dionex Corporation Apparatus/method for electrochemically modifying chromatographic material

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9964851A1 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2477287A (en) * 2010-01-27 2011-08-03 Izon Science Ltd Control of particle flow in an aperture
GB2477287B (en) * 2010-01-27 2012-02-15 Izon Science Ltd Control of particle flow in an aperture
US9052262B2 (en) 2010-01-27 2015-06-09 Izon Science Limited Control of particle flow in an aperture

Also Published As

Publication number Publication date
JP2002517751A (ja) 2002-06-18
CA2328400A1 (en) 1999-12-16
WO1999064851A1 (en) 1999-12-16

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