EP1051624A4 - Series haute densite pour l'analyse des proteomes et procedes et compositions pour ces derniers - Google Patents
Series haute densite pour l'analyse des proteomes et procedes et compositions pour ces derniersInfo
- Publication number
- EP1051624A4 EP1051624A4 EP99902461A EP99902461A EP1051624A4 EP 1051624 A4 EP1051624 A4 EP 1051624A4 EP 99902461 A EP99902461 A EP 99902461A EP 99902461 A EP99902461 A EP 99902461A EP 1051624 A4 EP1051624 A4 EP 1051624A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- high density
- density arrays
- proteome analysis
- compositions therefor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7296198P | 1998-01-29 | 1998-01-29 | |
US72961P | 1998-01-29 | ||
PCT/AU1999/000060 WO1999039210A1 (fr) | 1998-01-29 | 1999-01-29 | Series haute densite pour l'analyse des proteomes et procedes et compositions pour ces derniers |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1051624A1 EP1051624A1 (fr) | 2000-11-15 |
EP1051624A4 true EP1051624A4 (fr) | 2002-05-02 |
Family
ID=22110842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99902461A Withdrawn EP1051624A4 (fr) | 1998-01-29 | 1999-01-29 | Series haute densite pour l'analyse des proteomes et procedes et compositions pour ces derniers |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1051624A4 (fr) |
JP (1) | JP2002502038A (fr) |
AU (1) | AU740830B2 (fr) |
CA (1) | CA2319828A1 (fr) |
WO (1) | WO1999039210A1 (fr) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002502977A (ja) | 1998-02-04 | 2002-01-29 | インビトロジェン コーポレイション | マイクロアレイとその使用 |
GB9816514D0 (en) * | 1998-07-29 | 1998-09-30 | Smithkline Beecham Plc | Novel method |
JP2002532066A (ja) | 1998-11-16 | 2002-10-02 | ジェンウェイ バイオテック, インコーポレイテッド | 鳥類におけるポリヌクレオチドワクチンを用いる抗体の産生 |
DK2230303T3 (da) * | 1999-05-05 | 2013-04-15 | Phylogica Ltd | Isolering af biologiske modulatorer fra biodiverse genfragment-biblioteker |
GB9928787D0 (en) * | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
GB9928789D0 (en) * | 1999-12-03 | 2000-02-02 | Medical Res Council | Naive screening method |
US7816098B2 (en) | 2000-01-31 | 2010-10-19 | Sense Proteomic Limited | Methods of making and using a protein array |
JP4730804B2 (ja) * | 2000-01-31 | 2011-07-20 | センス・プロテオミック・リミテッド | 方法 |
AU3037501A (en) * | 2000-01-31 | 2001-08-14 | Sense Proteomic Limited | Methods |
EP1285092A4 (fr) | 2000-04-14 | 2003-07-16 | Metabolon Inc | Procedes permettant de decouvrir des medicaments, de traiter des maladies et de poser des diagnostics a l'aide de la metabolomique |
JP2004511753A (ja) * | 2000-05-04 | 2004-04-15 | イエール ユニバーシティー | タンパク質活性のスクリーニング用タンパク質チップ |
DE10023130B4 (de) * | 2000-05-11 | 2007-10-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Hyphenspezifische Faktoren aus Candida albicans |
US20020115068A1 (en) * | 2000-06-23 | 2002-08-22 | Ian Tomlinson | Matrix screening method |
EP1301632A2 (fr) * | 2000-07-19 | 2003-04-16 | Pointilliste, Inc. | Tri a plusieurs niveaux et le criblage a grande capacite |
IL137460A0 (en) * | 2000-07-24 | 2001-07-24 | Yeda Res & Dev | Identifying antigen clusters for monitoring a global state of an immune system |
US20020048823A1 (en) * | 2000-08-11 | 2002-04-25 | Qianjin Hu | Methods and universal monoclonal antibody array |
JP2004509645A (ja) * | 2000-08-17 | 2004-04-02 | センス・プロテオミック・リミテッド | 方法 |
US7094568B2 (en) | 2000-08-17 | 2006-08-22 | Sense Proteomic Ltd. | Method for producing proteins tagged at the N- or C-terminus |
WO2002025288A2 (fr) * | 2000-09-22 | 2002-03-28 | Clontech Laboratories Inc. | Procedes d'analyse proteomique a haute sensibilite, trousses et systemes utiles pour mettre en oeuvre ces derniers |
DE10054055A1 (de) | 2000-10-31 | 2002-05-23 | Nmi Univ Tuebingen | Verfahren zur Analyse von Proteinen |
WO2002039120A1 (fr) * | 2000-11-09 | 2002-05-16 | Bionova Pharmaceutials, Inc. | Procede d'identification du proteome de cellules utilisant un microreseau de banques d'anticorps |
US6905816B2 (en) | 2000-11-27 | 2005-06-14 | Intelligent Medical Devices, Inc. | Clinically intelligent diagnostic devices and methods |
WO2002046754A2 (fr) * | 2000-12-08 | 2002-06-13 | Neuronz Limited | Proteomique fonctionnelle mettant en oeuvre un double criblage avec expression a la surface de phages |
ATE513854T1 (de) * | 2000-12-13 | 2011-07-15 | Bac Ip B V | Proteinraster aus variablen domänen der schweren immunoglobulinkette von kamelen |
AU2002231028B2 (en) | 2000-12-14 | 2008-01-31 | Paul Stroobant | Differential phage capture proteomics |
DE10100122A1 (de) * | 2001-01-03 | 2002-07-11 | Henkel Kgaa | Verfahren zur Bestimmung der Hautalterung in vitro |
US7214498B2 (en) | 2001-03-23 | 2007-05-08 | Benaroya Research Institute At Virginia Mason | Tumor associated antigens and methods of using the same |
CA2443777A1 (fr) * | 2001-04-10 | 2002-10-24 | The Board Of Trustees Of The Leland Stanford Junior University | Utilisation therapeutique et diagnostique de profils de specificite d'anticorps |
WO2002084296A2 (fr) * | 2001-04-14 | 2002-10-24 | Aplagen Gmbh | Procede de selection de molecules de liaison immunologiques |
EP1249704A1 (fr) * | 2001-04-14 | 2002-10-16 | Frank, Hans-Georg c/o Lehrstuhl für Anatomie II Universitätsklinikum der RWTH | Procédé de selection des molecules liant immunologiques |
WO2002092118A1 (fr) * | 2001-05-11 | 2002-11-21 | Yale University | Analyse globale d'activites proteiques au moyen de puces proteomiques |
EP1401808B1 (fr) | 2001-05-24 | 2009-07-08 | Neuren Pharmaceuticals Limited | Peptidomimetiques et analogues de gpe |
US7714020B2 (en) | 2001-05-24 | 2010-05-11 | Neuren Pharmaceuticals Limited | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate |
US7605177B2 (en) | 2001-05-24 | 2009-10-20 | Neuren Pharmaceuticals Limited | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration |
US7863004B2 (en) * | 2001-12-04 | 2011-01-04 | Wayne State University | Neoepitope detection of disease using protein arrays |
EP1319954A1 (fr) * | 2001-12-12 | 2003-06-18 | Centre National de Genotypage | Methodes d'analyse des protéines qui utilisent des reseaux de capture |
US20030228709A1 (en) * | 2002-03-25 | 2003-12-11 | Kozlowski Roland Zbignieiw | Arrays |
WO2004046164A2 (fr) * | 2002-05-10 | 2004-06-03 | Engeneos, Inc. | Sequences de reconnaissance uniques et leurs procedes d'utilisation dans l'analyse de proteines |
US7618788B2 (en) | 2002-05-10 | 2009-11-17 | Millipore Corporation | Proteome epitope tags and methods of use thereof in protein modification analysis |
US7460960B2 (en) | 2002-05-10 | 2008-12-02 | Epitome Biosystems, Inc. | Proteome epitope tags and methods of use thereof in protein modification analysis |
CA2490522A1 (fr) * | 2002-06-20 | 2003-12-31 | Paul Stroobant | Procedes ameliores appliques a la proteomique par capture differentielle |
US7252954B2 (en) * | 2002-10-15 | 2007-08-07 | Abmetrix, Inc. | Sets of digital antibodies directed against short epitopes, and methods using same |
GB0305448D0 (en) * | 2003-03-10 | 2003-04-16 | Tcp Innovations Ltd | Immunoassay |
US20050208519A1 (en) * | 2004-03-12 | 2005-09-22 | Genenews Inc. | Biomarkers for diagnosing schizophrenia and bipolar disorder |
EP2270034A3 (fr) | 2004-06-03 | 2011-06-01 | Athlomics Pty Ltd | Agents et procédé permettant le diagnostic de stress |
EP1910565A4 (fr) | 2005-07-07 | 2009-10-28 | Athlomics Pty Ltd | Gènes à polynucléotides marqueurs et leur expression dans le diagnostique de l'endotoxémie |
CA2638912A1 (fr) | 2006-02-20 | 2007-08-30 | Phylogica Limited | Procede de construction et de criblage de bibliotheques de structures peptidiques |
US7855057B2 (en) | 2006-03-23 | 2010-12-21 | Millipore Corporation | Protein splice variant/isoform discrimination and quantitative measurements thereof |
JP2009543862A (ja) | 2006-07-14 | 2009-12-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ガンのバイオマーカーおよびその使用方法 |
WO2008147345A2 (fr) * | 2006-11-13 | 2008-12-04 | George Dacai Liu | Système et procédé pour la détection indépendante de la structure d'antigène d'antigènes capturés sur des matrices d'anticorps |
DK3255146T3 (da) | 2009-03-16 | 2019-08-19 | Pangu Biopharma Ltd | Præparater og fremgangsmåder omfattende histidyl-tRNA-synthetasesplejsningsvarianter med ikke-kanoniske biologiske aktiviteter |
US20100310576A1 (en) | 2009-03-31 | 2010-12-09 | Adams Ryan A | COMPOSITIONS AND METHODS COMPRISING ASPARTYL-tRNA SYNTHETASES HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES |
US8980253B2 (en) | 2010-04-26 | 2015-03-17 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase |
US20120003639A1 (en) | 2010-04-27 | 2012-01-05 | Prelude, Inc. | Cancer biomarkers and methods of use thereof |
CN103096911B (zh) | 2010-04-27 | 2018-05-29 | Atyr 医药公司 | 与异亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
AU2011248489B2 (en) | 2010-04-28 | 2016-10-06 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl tRNA synthetases |
WO2011150279A2 (fr) | 2010-05-27 | 2011-12-01 | Atyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, de diagnostic et d'anticorps liées à fragments protéiques de glutaminyl-arnt synthétases |
CN103097523B (zh) | 2010-04-29 | 2016-09-28 | Atyr医药公司 | 与天冬酰胺酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
EP2563383B1 (fr) | 2010-04-29 | 2017-03-01 | Atyr Pharma, Inc. | Découverte innovatrice de compositions thérapeutiques, diagnostiques, et d'anticorps associées aux fragments protéiques des valyle arnt synthétases |
CA2800557A1 (fr) | 2010-04-29 | 2011-11-03 | Medical Prognosis Institute A/S | Methodes et dispositifs permettant de predire l'efficacite d'un traitement |
CA2797277C (fr) | 2010-05-03 | 2021-02-23 | Atyr Pharma, Inc. | Decouverte innovante de compositions therapeutiques, de diagnostic et d'anticorps liees a des fragments proteiques d'arginyle-arnt synthetases |
EP2566496B1 (fr) | 2010-05-03 | 2018-02-28 | aTyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, diagnostiques et à base d'anticorps liées des fragments protéiques de méthionyl-arnt-synthétases |
US9034321B2 (en) | 2010-05-03 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases |
CA2798139C (fr) | 2010-05-04 | 2019-09-24 | Atyr Pharma, Inc. | Decouverte innovante de compositions therapeutiques, diagnostiques et a base d'anticorps liees a des fragments proteiques de complexe multi-arnt synthetase p38 |
CN103200953B (zh) | 2010-05-14 | 2017-02-15 | Atyr 医药公司 | 与苯丙氨酰‑β‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
CN103096914B (zh) | 2010-05-17 | 2015-08-12 | Atyr医药公司 | 与亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
AU2011261486B2 (en) | 2010-06-01 | 2017-02-23 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-tRNA synthetases |
WO2011159959A2 (fr) * | 2010-06-16 | 2011-12-22 | Cdi Laboratories | Procédés et systèmes permettant de générer, de valider et d'utiliser des anticorps monoclonaux |
EP2593125B1 (fr) | 2010-07-12 | 2017-11-01 | aTyr Pharma, Inc. | DÉCOUVERTE INNOVANTE DE COMPOSITIONS THÉRAPEUTIQUES, DE DIAGNOSTIC ET D'ANTICORPS SE RAPPORTANT À DES FRAGMENTS PROTÉIQUES DE GLYCYL-ARNt SYNTHÉTASES |
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- 1999-01-29 EP EP99902461A patent/EP1051624A4/fr not_active Withdrawn
- 1999-01-29 AU AU22597/99A patent/AU740830B2/en not_active Ceased
- 1999-01-29 JP JP2000529613A patent/JP2002502038A/ja active Pending
- 1999-01-29 CA CA002319828A patent/CA2319828A1/fr not_active Abandoned
- 1999-01-29 WO PCT/AU1999/000060 patent/WO1999039210A1/fr not_active Application Discontinuation
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Also Published As
Publication number | Publication date |
---|---|
EP1051624A1 (fr) | 2000-11-15 |
WO1999039210A1 (fr) | 1999-08-05 |
AU2259799A (en) | 1999-08-16 |
JP2002502038A (ja) | 2002-01-22 |
CA2319828A1 (fr) | 1999-08-05 |
AU740830B2 (en) | 2001-11-15 |
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