EP1042943A1 - Milieu d'irrigation pour canaux radiculaires - Google Patents

Milieu d'irrigation pour canaux radiculaires

Info

Publication number
EP1042943A1
EP1042943A1 EP98965457A EP98965457A EP1042943A1 EP 1042943 A1 EP1042943 A1 EP 1042943A1 EP 98965457 A EP98965457 A EP 98965457A EP 98965457 A EP98965457 A EP 98965457A EP 1042943 A1 EP1042943 A1 EP 1042943A1
Authority
EP
European Patent Office
Prior art keywords
solution
aqueous
anion
electro
cation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98965457A
Other languages
German (de)
English (en)
Other versions
EP1042943A4 (fr
Inventor
Jacobus Theodorus Marais
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Radical Waters IP Pty Ltd
Original Assignee
Radical Waters IP Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radical Waters IP Pty Ltd filed Critical Radical Waters IP Pty Ltd
Publication of EP1042943A1 publication Critical patent/EP1042943A1/fr
Publication of EP1042943A4 publication Critical patent/EP1042943A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C5/00—Filling or capping teeth
    • A61C5/40—Implements for surgical treatment of the roots or nerves of the teeth; Nerve needles; Methods or instruments for medication of the roots
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/52—Cleaning; Disinfecting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Definitions

  • This invention relates to the use of antiseptics in root canal treatment so as
  • Sodium hypochlorite is universally used as an antiseptic for root canal
  • sodium hypochlorite is that it is highly toxic to human tissues and cells in
  • aqueous solution characterised in that
  • aqueous anion-containing solution may consist of an aqueous anion-containing and/or an aqueous cation-containing solution.
  • aqueous cation-containing solution may be prepared by means of
  • the salt may be sodium
  • chloride In particular, it may be non-iodated sodium chloride or potassium
  • the anion-containing and the associated cation-containing solution may be
  • the anion-containing solution is referred to hereinafter for brevity as the
  • anolyte solution and the cation-containing solution is referred to
  • the catholyte solution are preferably provided from an electro-chemical
  • reactor comprising a through-flow, electro-chemical cell having two co-axial
  • the anolyte solution may be produced from a 10% aqueous NaCI solution,
  • the anolyte solution may include activated radical species such as CIO;
  • the activated radical species have been found to have a synergistic anti ⁇
  • viral organisms including Gram positive and
  • Gram negative bacteria such as Enterococcus faecalis and Pseudomonas
  • the catholyte solution generally may have a pH of up to about 7-13 and a
  • the catholyte solution may include
  • activated radical species such as NaOH; KOH; Ca(OH) 2 ; Mg (OH) 2 ; HO ' ;
  • anolyte solution act synergistically as a biocidal and virucidal
  • catholyte solution in the preparation of an irrigating medium for use in the
  • ORP ORP
  • the exposure time i.e. the contact time between the root canal
  • Anolyte has been found to be more effective at lower than at
  • the irrigating medium comprising an
  • aqueous solution being substantially as hereinbefore defined.
  • irrigating root canals including the step of applying an clectro-chemically
  • the method of irrigating root canals may include the steps of first applying
  • catholyte solution to the root canal aimed at removing organic biofilm
  • Group A sodium hypochlorite
  • the root canals of Group A were prepared, using a series of K-
  • STEDS produced included two separate solutions, namely
  • the catholyte and anolyte solutions had a pH
  • the catholyte solution had a pH of about 9,5 and a redox potential
  • Root canals in Group B were prepared using the same
  • the specimens were placed into a dust-free incubator and allowed to air-dry for 10 days.
  • the air-dried specimens were mounted with conductive
  • metal spreader over the surface of the plates. After overnight
  • tuberculin syringe 30 ⁇ i saline was then aspirated from the root canals, serially diluted and spread plated onto 10% blood
  • hypoclorite for 5 and 10 minutes respectively. After 5 minutes
  • the broth was shown to contain 4.4 x 10 10 cfus after 7 days'
  • catholyte is known to act in a similar way to a detergent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dentistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Abstract

Cette invention concerne des antiseptiques que l'on utilise dans le traitement de canaux radiculaires. Ces antiseptiques permettent de freiner la prolifération de bactéries et d'autres micro-organismes restant dans un canal radiculaire après obturation de celui-ci.
EP98965457A 1997-12-30 1998-12-24 Milieu d'irrigation pour canaux radiculaires Withdrawn EP1042943A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA9711702 1997-12-30
ZA9711702 1997-12-30
PCT/US1998/027380 WO1999034652A1 (fr) 1997-12-30 1998-12-24 Milieu d'irrigation pour canaux radiculaires

Publications (2)

Publication Number Publication Date
EP1042943A1 true EP1042943A1 (fr) 2000-10-11
EP1042943A4 EP1042943A4 (fr) 2002-05-02

Family

ID=25586798

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98965457A Withdrawn EP1042943A4 (fr) 1997-12-30 1998-12-24 Milieu d'irrigation pour canaux radiculaires

Country Status (4)

Country Link
EP (1) EP1042943A4 (fr)
JP (1) JP2002500055A (fr)
AU (1) AU2091899A (fr)
WO (1) WO1999034652A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2355190B (en) 1999-08-23 2004-07-28 Sterilox Medical Improvements in or relating to sterilising preparations
US6426066B1 (en) 2000-01-12 2002-07-30 California Pacific Labs, Inc. Use of physiologically balanced, ionized, acidic solution in wound healing
US7393522B2 (en) 2000-01-12 2008-07-01 Novabay Pharmaceuticals, Inc. Physiologically balanced, ionized, acidic solution and methodology for use in wound healing
EP1383461B1 (fr) * 2000-12-15 2011-05-04 Radical Waters IP (PTY) Ltd Fluide de refroidissement et d'irrigation utilise dans la chirurgie dentaire
WO2003049750A1 (fr) * 2001-12-10 2003-06-19 Radical Waters (Ip) (Pty) Limited Traitement des pathologies infectieuses des muqueuses et des tissus cutaneo-muqueux
JP5409796B2 (ja) * 2008-11-05 2014-02-05 メディクエヌ．アール．ジー． リミテッド 歯腔処置のための装置と方法
US8871278B2 (en) 2011-03-18 2014-10-28 Puricore, Inc. Stabilized hypohalous acid solutions
US11452778B2 (en) 2011-03-18 2022-09-27 Urgo Us, Inc. Stabilized hypohalous acid solutions
US9381214B2 (en) 2011-03-18 2016-07-05 Puricore, Inc. Methods for treating skin irritation
RU2724850C1 (ru) * 2016-07-22 2020-06-25 Конинклейке Филипс Н.В. Введение противомикробных препаратов для ухода за полостью рта

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1939790A1 (de) * 1968-08-05 1970-02-05 Gwynn Ross Merton Verfahren zum Erzeugen von erhoehter,biozider Aktivitaet bei der Elektrolyse von chlorhaltigen Loesungen
FR2131816A1 (en) * 1971-03-29 1972-11-17 Caillot Jean Perchloric acid and salts - for clearing and disinfecting dental canals
DE3637887A1 (de) * 1986-11-06 1988-05-19 Wolf Schillinger Vorrichtung zum transport dissoziierender medikamente
WO1996006959A1 (fr) * 1994-08-26 1996-03-07 Medical Discoveries, Inc. Systeme d'electrolyse de fluides administres a des etres humains ou a d'autres mammiferes a sang chaud
WO1997019597A1 (fr) * 1995-11-29 1997-06-05 Marco Rotondi Composition a usage odontostomatologique permettant le nettoyage et la desinfection des canaux radiculaires et de la dentine vivante

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622848A (en) * 1990-05-23 1997-04-22 Medical Discoveries, Inc. Electrically hydrolyzed salines as microbiocides for in vitro treatment of contaminated fluids containing blood

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1939790A1 (de) * 1968-08-05 1970-02-05 Gwynn Ross Merton Verfahren zum Erzeugen von erhoehter,biozider Aktivitaet bei der Elektrolyse von chlorhaltigen Loesungen
FR2131816A1 (en) * 1971-03-29 1972-11-17 Caillot Jean Perchloric acid and salts - for clearing and disinfecting dental canals
DE3637887A1 (de) * 1986-11-06 1988-05-19 Wolf Schillinger Vorrichtung zum transport dissoziierender medikamente
WO1996006959A1 (fr) * 1994-08-26 1996-03-07 Medical Discoveries, Inc. Systeme d'electrolyse de fluides administres a des etres humains ou a d'autres mammiferes a sang chaud
WO1997019597A1 (fr) * 1995-11-29 1997-06-05 Marco Rotondi Composition a usage odontostomatologique permettant le nettoyage et la desinfection des canaux radiculaires et de la dentine vivante

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
INOUE, YOSHIHIRO ET AL: "Trial of electrolyzed strong acid aqueous solution lavage in the treatment of peritonitis and intraperitoneal abscess" ARTIF. ORGANS (1997), 21(1), 28-31 , XP001064985 *
KETTERL, A. L.: "[ Dental ] root treatment and ionophoresis" DEUT. DENTIST Z. (1950), 4, 801-3 FROM: CHEM. ZENTR. 1952, 410., XP001059037 *
See also references of WO9934652A1 *
TENYGL, JIRI: "The use of short-circuited galvanic cells in dentistry" BIOELECTROCHEM. BIOENERG. (1983), 10(2-3), 301-7 , XP001064980 *

Also Published As

Publication number Publication date
WO1999034652A1 (fr) 1999-07-08
EP1042943A4 (fr) 2002-05-02
JP2002500055A (ja) 2002-01-08
AU2091899A (en) 1999-07-19

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