Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
  • A61C5/00—Filling or capping teeth
  • A61C5/40—Implements for surgical treatment of the roots or nerves of the teeth; Nerve needles; Methods or instruments for medication of the roots
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K6/00—Preparations for dentistry
  • A61K6/50—Preparations specially adapted for dental root treatment
  • A61K6/52—Cleaning; Disinfecting
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
  • A61P31/02—Local antiseptics
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Definitions

• This invention relates to the use of antiseptics in root canal treatment so as
• Sodium hypochlorite is universally used as an antiseptic for root canal
• sodium hypochlorite is that it is highly toxic to human tissues and cells in
• aqueous solution characterised in that
• aqueous anion-containing solution may consist of an aqueous anion-containing and/or an aqueous cation-containing solution.
• aqueous cation-containing solution may be prepared by means of
• the salt may be sodium
• chloride In particular, it may be non-iodated sodium chloride or potassium
• the anion-containing and the associated cation-containing solution may be
• the anion-containing solution is referred to hereinafter for brevity as the
• anolyte solution and the cation-containing solution is referred to
• the catholyte solution are preferably provided from an electro-chemical
• reactor comprising a through-flow, electro-chemical cell having two co-axial
• the anolyte solution may be produced from a 10% aqueous NaCI solution,
• the anolyte solution may include activated radical species such as CIO;
• the activated radical species have been found to have a synergistic anti ⁇
• viral organisms including Gram positive and
• Gram negative bacteria such as Enterococcus faecalis and Pseudomonas
• the catholyte solution generally may have a pH of up to about 7-13 and a
• the catholyte solution may include
• activated radical species such as NaOH; KOH; Ca(OH) 2 ; Mg (OH) 2 ; HO ' ;
• anolyte solution act synergistically as a biocidal and virucidal
• catholyte solution in the preparation of an irrigating medium for use in the
• ORP ORP
• the exposure time i.e. the contact time between the root canal
• Anolyte has been found to be more effective at lower than at
• the irrigating medium comprising an
• aqueous solution being substantially as hereinbefore defined.
• irrigating root canals including the step of applying an clectro-chemically
• the method of irrigating root canals may include the steps of first applying
• catholyte solution to the root canal aimed at removing organic biofilm
• Group A sodium hypochlorite
• the root canals of Group A were prepared, using a series of K-
• STEDS produced included two separate solutions, namely
• the catholyte and anolyte solutions had a pH
• the catholyte solution had a pH of about 9,5 and a redox potential
• Root canals in Group B were prepared using the same
• the specimens were placed into a dust-free incubator and allowed to air-dry for 10 days.
• the air-dried specimens were mounted with conductive
• metal spreader over the surface of the plates. After overnight
• tuberculin syringe 30 ⁇ i saline was then aspirated from the root canals, serially diluted and spread plated onto 10% blood
• hypoclorite for 5 and 10 minutes respectively. After 5 minutes
• the broth was shown to contain 4.4 x 10 10 cfus after 7 days'
• catholyte is known to act in a similar way to a detergent

Landscapes

• Health & Medical Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Veterinary Medicine (AREA)
• Public Health (AREA)
• General Health & Medical Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• Oral & Maxillofacial Surgery (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• Medicinal Chemistry (AREA)
• Surgery (AREA)
• Organic Chemistry (AREA)
• General Chemical & Material Sciences (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Chemical & Material Sciences (AREA)
• Epidemiology (AREA)
• Engineering & Computer Science (AREA)
• Pharmacology & Pharmacy (AREA)
• Bioinformatics & Cheminformatics (AREA)
• Biomedical Technology (AREA)
• Neurology (AREA)
• Neurosurgery (AREA)
• Communicable Diseases (AREA)
• Dentistry (AREA)
• Oncology (AREA)
• Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
• Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Applications Claiming Priority (3)

Publications (2)

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Citations (5)

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• 1998
  • 1998-12-24 EP EP98965457A patent/EP1042943A4/de not_active Withdrawn
  • 1998-12-24 JP JP2000527130A patent/JP2002500055A/ja active Pending
  • 1998-12-24 WO PCT/US1998/027380 patent/WO1999034652A1/en not_active Application Discontinuation
  • 1998-12-24 AU AU20918/99A patent/AU2091899A/en not_active Abandoned

Patent Citations (5)

Non-Patent Citations (4)

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