EP1019046A4 - Protease inhibitors - Google Patents
Protease inhibitorsInfo
- Publication number
- EP1019046A4 EP1019046A4 EP98920926A EP98920926A EP1019046A4 EP 1019046 A4 EP1019046 A4 EP 1019046A4 EP 98920926 A EP98920926 A EP 98920926A EP 98920926 A EP98920926 A EP 98920926A EP 1019046 A4 EP1019046 A4 EP 1019046A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- protease inhibitors
- protease
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4506797P | 1997-04-29 | 1997-04-29 | |
| US45067 | 1997-04-29 | ||
| PCT/US1998/008740 WO1998048799A1 (en) | 1997-04-29 | 1998-04-29 | Protease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1019046A1 EP1019046A1 (en) | 2000-07-19 |
| EP1019046A4 true EP1019046A4 (en) | 2002-11-27 |
Family
ID=21935831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP98920926A Withdrawn EP1019046A4 (en) | 1997-04-29 | 1998-04-29 | Protease inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1019046A4 (en) |
| JP (1) | JP2002504097A (en) |
| KR (1) | KR20010020391A (en) |
| CN (1) | CN1261276A (en) |
| AR (1) | AR012622A1 (en) |
| AU (1) | AU7365198A (en) |
| BR (1) | BR9809333A (en) |
| CA (1) | CA2287989A1 (en) |
| CO (1) | CO4940477A1 (en) |
| HU (1) | HUP0001294A3 (en) |
| IL (1) | IL132629A0 (en) |
| MA (1) | MA26487A1 (en) |
| NO (1) | NO995268L (en) |
| PE (1) | PE69099A1 (en) |
| PL (1) | PL337725A1 (en) |
| TR (1) | TR199902703T2 (en) |
| WO (1) | WO1998048799A1 (en) |
| ZA (1) | ZA983522B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1924699A (en) | 1997-12-19 | 1999-07-12 | Smithkline Beecham Corporation | Compounds of heteroaryl substituted imidazole, their pharmaceutical compositionsand uses |
| US6100282A (en) * | 1998-01-02 | 2000-08-08 | Hoffman-La Roche Inc. | Thiazole derivatives |
| MA26618A1 (en) * | 1998-04-09 | 2004-12-20 | Smithkline Beecham Corp | PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF MALARIA |
| US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| AU1909200A (en) | 1998-11-04 | 2000-05-22 | Smithkline Beecham Corporation | Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines |
| CO5150165A1 (en) * | 1998-11-13 | 2002-04-29 | Smithkline Beecham Plc | PROTEASE INHIBITORS: KATEPSIN K TYPE |
| US20030144175A1 (en) | 1998-12-23 | 2003-07-31 | Smithkline Beecham Corporation | Protease inhibitors |
| WO2001034599A1 (en) | 1999-11-10 | 2001-05-17 | Smithkline Beecham Corporation | Protease inhibitors |
| WO2001034600A1 (en) | 1999-11-10 | 2001-05-17 | Smithkline Beecham Corporation | Protease inhibitors |
| US6534498B1 (en) | 1999-11-10 | 2003-03-18 | Smithkline Beecham Corporation | Protease inhibitors |
| US6797720B2 (en) | 1999-12-03 | 2004-09-28 | Ono Pharmaceutical Co., Ltd. | 1,3,4-oxadiazoline derivative and an agent comprising its derivative as active ingredient |
| EP1234821A4 (en) * | 1999-12-03 | 2002-10-28 | Ono Pharmaceutical Co | 1,3,4-oxadiazoline derivatives and drugs containing these derivatives as the active ingredient |
| AU2001243441B2 (en) | 2000-03-21 | 2004-11-25 | Smithkline Beecham Corporation | Protease inhibitors |
| JP2005515254A (en) | 2002-01-17 | 2005-05-26 | スミスクライン ビーチャム コーポレーション | Cycloalkylketoamide derivatives useful as cathepsin K inhibitors |
| CA2490468A1 (en) * | 2002-07-04 | 2004-01-22 | Aventis Pharma S.A. | Novel thiophene acyl hydrazino derivatives, method for preparing same, use thereof as medicines, pharmaceutical compositions and novel use |
| KR100962972B1 (en) | 2002-07-26 | 2010-06-09 | 주식회사유한양행 | 1-phenylpiperidin-3-one derivatives and processes for the preparation thereof |
| WO2011015524A2 (en) * | 2009-08-03 | 2011-02-10 | Bayer Cropscience Ag | Fungicide heterocycles derivatives |
| NZ704666A (en) * | 2012-08-23 | 2018-05-25 | Alios Biopharma Inc | Compounds for the treatment of paramoxyvirus viral infections |
| EP3036220A4 (en) | 2013-08-21 | 2017-04-12 | Alios Biopharma, Inc. | Antiviral compounds |
| MA41614A (en) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | ANTIVIRAL COMPOUNDS |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR19990067184A (en) * | 1995-10-30 | 1999-08-16 | 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 | Protease inhibitor |
-
1998
- 1998-04-24 MA MA25047A patent/MA26487A1/en unknown
- 1998-04-27 PE PE1998000320A patent/PE69099A1/en not_active Application Discontinuation
- 1998-04-28 ZA ZA983522A patent/ZA983522B/en unknown
- 1998-04-29 BR BR9809333-9A patent/BR9809333A/en not_active IP Right Cessation
- 1998-04-29 JP JP54738998A patent/JP2002504097A/en active Pending
- 1998-04-29 HU HU0001294A patent/HUP0001294A3/en unknown
- 1998-04-29 CO CO98023491A patent/CO4940477A1/en unknown
- 1998-04-29 AR ARP980101999A patent/AR012622A1/en unknown
- 1998-04-29 CA CA002287989A patent/CA2287989A1/en not_active Abandoned
- 1998-04-29 CN CN98806641A patent/CN1261276A/en active Pending
- 1998-04-29 TR TR1999/02703T patent/TR199902703T2/en unknown
- 1998-04-29 PL PL98337725A patent/PL337725A1/en unknown
- 1998-04-29 EP EP98920926A patent/EP1019046A4/en not_active Withdrawn
- 1998-04-29 IL IL13262998A patent/IL132629A0/en unknown
- 1998-04-29 KR KR1019997010013A patent/KR20010020391A/en not_active Application Discontinuation
- 1998-04-29 AU AU73651/98A patent/AU7365198A/en not_active Abandoned
- 1998-04-29 WO PCT/US1998/008740 patent/WO1998048799A1/en not_active Application Discontinuation
-
1999
- 1999-10-28 NO NO995268A patent/NO995268L/en not_active Application Discontinuation
Non-Patent Citations (1)
| Title |
|---|
| No further relevant documents disclosed * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010020391A (en) | 2001-03-15 |
| PE69099A1 (en) | 1999-09-26 |
| AR012622A1 (en) | 2000-11-08 |
| IL132629A0 (en) | 2001-03-19 |
| CO4940477A1 (en) | 2000-07-24 |
| NO995268L (en) | 1999-11-15 |
| MA26487A1 (en) | 2004-12-20 |
| HUP0001294A3 (en) | 2001-06-28 |
| AU7365198A (en) | 1998-11-24 |
| PL337725A1 (en) | 2000-08-28 |
| WO1998048799A1 (en) | 1998-11-05 |
| BR9809333A (en) | 2000-07-04 |
| NO995268D0 (en) | 1999-10-28 |
| JP2002504097A (en) | 2002-02-05 |
| HUP0001294A2 (en) | 2001-04-28 |
| ZA983522B (en) | 1998-10-29 |
| CN1261276A (en) | 2000-07-26 |
| TR199902703T2 (en) | 2000-02-21 |
| EP1019046A1 (en) | 2000-07-19 |
| CA2287989A1 (en) | 1998-11-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL336625A1 (en) | Protease inhibitors | |
| PL336589A1 (en) | Serinic protease inhibitors | |
| PL349192A1 (en) | Protease inhibitors | |
| ZA98376B (en) | Sulfamide-metalloprotease inhibitors | |
| GB2321641B (en) | Sulfamide-metalloprotease inhibitors | |
| PL328307A1 (en) | Serinic protease inhibitors | |
| EP0744948A4 (en) | Protease inhibitors | |
| HUP0002247A3 (en) | Protease inhibitors | |
| IL132630A0 (en) | Protease inhibitors | |
| EP1093367A4 (en) | Protease inhibitors | |
| ZA983522B (en) | Protease inhibitors | |
| ZA988479B (en) | Protease inhibitors | |
| PL328875A1 (en) | Serinic protease inhibitors | |
| PL328223A1 (en) | Aspartil protease inhibitors | |
| EP1067894A4 (en) | Protease inhibitors | |
| EP1079821A4 (en) | Protease inhibitors | |
| ZA988064B (en) | Protease inhibitors | |
| EP1086083A4 (en) | Protease inhibitors | |
| EP1140897A4 (en) | Protease inhibitors | |
| EP0975612A4 (en) | Protease inhibitors | |
| ZA983097B (en) | Protease inhibitors | |
| ZA977032B (en) | Protease inhibitors | |
| GB9420277D0 (en) | Protease inhibitors | |
| GB9727371D0 (en) | Inhibitors | |
| GB9725783D0 (en) | Inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19991117 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
| AX | Request for extension of the european patent |
Free format text: SI PAYMENT 19991117 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20021014 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20030104 |