EP1007211A1 - Dispositif de saisie et de distribution d'objets utilises en laboratoire au moins partiellement de forme cylindrique creuse - Google Patents

Dispositif de saisie et de distribution d'objets utilises en laboratoire au moins partiellement de forme cylindrique creuse

Info

Publication number
EP1007211A1
EP1007211A1 EP98922637A EP98922637A EP1007211A1 EP 1007211 A1 EP1007211 A1 EP 1007211A1 EP 98922637 A EP98922637 A EP 98922637A EP 98922637 A EP98922637 A EP 98922637A EP 1007211 A1 EP1007211 A1 EP 1007211A1
Authority
EP
European Patent Office
Prior art keywords
objects
plate
receiving
actuating
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98922637A
Other languages
German (de)
English (en)
Inventor
Bernd Steinbrenner
Roger Steinbrenner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Steinbrenner Bernd Dr
Original Assignee
Steinbrenner Bernd Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19714135A external-priority patent/DE19714135C1/de
Application filed by Steinbrenner Bernd Dr filed Critical Steinbrenner Bernd Dr
Publication of EP1007211A1 publication Critical patent/EP1007211A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/50—Clamping means, tongs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/023—Adapting objects or devices to another adapted for different sizes of tubes, tips or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric

Definitions

  • Removal and delivery device for objects for laboratory use which at least partially have a hollow cylindrical contour
  • the invention relates to a removal and delivery device for objects for laboratory use, which at least partially have a hollow cylindrical contour, such as pipette tips, test tubes, test tubes or cuvettes, the device having a plate-like body with receiving devices which are designed and arranged in such a way that in one standardized grid with high packing density with the opening facing upwards can be removed from a first carrier and transferred to another carrier,
  • a shoulder is often provided on the outside, which serves as a support when the pipette tips are to be picked up by a pipette from a perforated plate-shaped carrier.
  • the pipette tips can be packed loose in bags and must then be individually attached to the pipettes by hand. This procedure runs the risk of touching the tips by hand and thus contaminating them. In the case of a large number of pipetting processes, this method is also very complex.
  • pipette tips can therefore also be attached to carriers which are usually made of plastic, the carriers being closable by covers.
  • the carriers have perforated plates, the most manufacturers or providers use a standardized, orthogonal 8x12 or
  • a holder for reagent vessels arranged in a grid is known, but this is not used to transfer from one carrier to another carrier. Rather, the objects are inserted by hand in order to then "move" the holder from one workstation to the next. After the test tubes have been used up, a holding device is released in order to dispose of the test tubes. However, the holding device is a complex and relatively space-consuming mechanism is to be removed from a person not suitable for transferring them to another carrier in their standardized grid.
  • two plates are provided with receiving openings in a grid-like arrangement, between which the holding device is arranged. The latter consists of leaf springs, one of which is assigned to a receiving device.
  • the leaf springs are actuated in rows by shafts, the actuation of the shafts being carried out by a control rail via a locking bar.
  • a holding device it is not possible, or not at reasonable cost, to clamp objects arranged in a narrow grid on their circumference.
  • the objects mentioned at the outset for example pipette tips, are arranged on supports in a standardized grid which is very compact and has extremely little space between the objects.
  • the invention is therefore based on the object of designing a device of the type mentioned at the outset in such a way that the conversion process can be carried out simply and safely.
  • an actuating plate extends parallel to the plate-like body over the area of the receiving devices and can be moved relative to the plate-like body by means of an actuating device, as a result of which the receiving devices can be brought into three working states, a first working state in which the objects are recordable, a second working state in which they clamply hold the objects and a third working state in which the objects can be released.
  • Another solution to the problem is that the plate-like body as receiving devices at least at the points where it comes to rest on the objects has an underside to which the objects adhere, and that the plate-like body after the objects have been brought onto the other carrier is detachable from the objects.
  • the device according to the invention means that the repositioning body and carrier no longer have to be turned over.
  • the objects are removed from one carrier, brought to the other carrier and used there in the simplest way.
  • the objects can be inserted from above into the receiving openings of the carrier to be filled, which is much easier than from below.
  • the objects are also exactly in the grid due to the clamping or adhesion, which cannot be achieved with the relocating body according to the prior art because of the play between pipette tips and receiving pins and their upside-down position. Handling is therefore easier and safer, and there is no risk of falling out, as is the case when turning over as is known in the prior art.
  • the risk of the objects being touched when moving them is also significantly lower, which is particularly important in the case of high cleanliness requirements.
  • the mechanics of the proposals according to the invention are simple and space-saving.
  • it is suitable for picking up, holding and releasing objects arranged in a narrow grid, in particular in the usual standardized grids.
  • the objects can be packed tightly and delivered and stored in a space-saving manner, and it is possible, while maintaining this grid, to arrange them on the customary carriers which are intended for the use of the objects.
  • the removal and dispensing device of the first proposal according to the invention can be constructed such that the receiving devices grip the objects on the outside, that they grip the objects on their walls or that they grip the objects in their openings.
  • the relative mobility of the actuating plate relative to the plate-like body which serves to bring the receiving devices into their different working states, can be designed in different ways.
  • One embodiment provides that the actuating plate is displaceable parallel to the plate-like body, and another embodiment provides that the relative mobility is a change in the distance between the plate-like body and the actuating plate.
  • a further development provides that the relative movement between the plate-like body and the actuating plate takes place against a spring force, the objects being held in a locked state by the receiving devices by means of the spring force and the receiving devices by actuating against the spring force in the working states for receiving and are releasable to release the items.
  • the advantage of this embodiment is that the objects are held securely by the spring force and an inadvertent loosening of the receiving devices is almost impossible.
  • An expedient embodiment provides that the relative movement between the plate-like body and the actuating plate takes place from the first to the second working state by the inclusion of the objects in the receiving devices and that the relative movement is effected from the second to the third working state by actuating the actuating device. In this way, the operation of the removal and dispensing device is further simplified.
  • One of the specific configurations is based on the principle that the receiving devices have vertically projecting receiving pins.
  • Such receptacle pins ensure particularly good guidance and alignment of the objects, so that their lower ends are also in the exact grid and can be easily inserted into the receptacle openings of a carrier.
  • the receiving pins are designed in such a way that their diameter can be changed by means of an actuating device in such a way that it ner and once larger than the diameter of the openings of the objects.
  • the receiving pins themselves serve as a clamping device for holding the objects so that they can be removed from one carrier and placed in the other carrier.
  • the receiving pins have resilient holding arms which can be elastically spread apart by means of an expansion body which can be axially displaced by the actuating device and a wedge-shaped surface arrangement.
  • the receiving pins usually have a diameter that is smaller than the openings of the objects.
  • the same effect can also be achieved in a different way, for example in that the receiving pins have resilient holding arms which extend outwards and can be compressed by means of a circumference which can be displaced axially by the actuating device. So the opposite way is followed, the recording pins have to be pressed together before they are inserted into the objects and they are released by pulling back the enclosure.
  • the holding arms it is also possible for the holding arms to have such bevels that they are compressed by them themselves when they are introduced into the objects. Due to their spring force, the holding arms go into the spread position in which they hold the objects.
  • the receiving pins are designed as holding arms, it is expedient for good, centered holding of the objects if the receiving pins have three holding arms. These are arranged axially symmetrically and of the same size and elasticity.
  • the receiving pins are designed as elastic bodies inserted between two surfaces, the latter being dimensioned such that they can have the two diameters in the two working states by changing the distance of the surfaces by means of the actuating device.
  • a device with receiving pins can also be designed in such a way that the receiving pins have an elasticity with regard to their diameter such that the objects can be clamped on them, but can also be wiped off, and that the wiping of clamped objects takes place by means of a wiper and an actuating device can be.
  • the scraper can be designed as webs or as a comb, but it is most expedient to design it as a perforated plate, which is adjustable in height in the region of the receiving pins, but is held captive.
  • the stripper can be a grid-shaped perforated plate, the holes of which surround the receiving pins.
  • the scraper can be a separate plate or the scraper - designed as a perforated plate, comb or component with webs - is also an actuating plate.
  • the scraper can be pushed away from the receiving area of the receiving pins when the objects are picked up by the latter and can be pressed down by the actuating device in such a way that the objects leave the receiving area.
  • the handling of such a device is particularly simple, it only needs to be placed on a carrier with objects and pressed down. As a result, the objects are clamped onto the pick-up pins and the wiper reaches the position in which it is ready for the wiping process. If the objects have been placed on a new carrier, the stripper only needs to be triggered by the actuating device in order to strip the objects from the receiving pins so that they fall into the receiving openings of the carrier.
  • the device can also be designed without receiving pins, in that the receiving devices are clamping bodies, by means of which the objects can be clamped and released on their circumference.
  • the clamping bodies clamp and release the objects at their opening or their wall.
  • Such clamping bodies can be, for example, elastic grippers or holding elements, which can have a wide variety of configurations.
  • the Klemmgro ⁇ er can also be grippers which can be brought into a clamping and a release position by means of an actuating device. In this case, the grippers themselves are operatively connected to the actuating device.
  • at least two clamping bodies are arranged concentrically per receiving device in such a way that objects of different diameters can be held.
  • At least one clamping body to be designed as an elastic lattice structure with grid-shaped receiving openings.
  • This configuration can be such that the objects are clamped when the device is placed on due to the elasticity of the clamping bodies, for example elastic grippers or flexible openings, and that the objects can be removed from the receiving devices of the clamping bodies by means of an ejector which is operated with an actuating device in Active connection is established.
  • the receiving devices are designed as receiving openings, the width of which can be made narrower and wider than the diameter of the objects by means of an actuating device.
  • a device can be designed, for example, in such a way that lattice structures or perforated plates which are displaceable relative to one another are provided.
  • the Klemmkö ⁇ er is a strong elastic body inserted between two fixed plates, the latter and at least one of the plates serving as receiving devices receiving openings that are slightly larger than the diameter of the objects and by means of the compression of the plates by means an actuating device in the area of the highly elastic body can be narrowed in such a way that they clamp objects lying in them.
  • Such a device is particularly suitable for an inexpensive production, since a sandwich-like body with two fixed plates and a very elastic intermediate layer only has to be provided with the corresponding bores in order to produce a large number of receiving devices in this way.
  • Another design principle is to design a device with an actuating plate which can be displaced parallel to the plate-like body in such a way that at least one fixed holding element and at least one displaceable holding element are arranged per receiving device such that an object J o can be clamped, held or released, or inserted.
  • the receiving devices can grip the objects on their outside, on their walls or in their openings.
  • the at least one fixed holding element on the plate-like body and the at least one displaceable holding element can be arranged on a displaceable actuating plate for each receiving device.
  • At least one spring between the plate-like body and the displaceable actuating plate for applying the clamping force.
  • a manual operation must then take place to pick up and drop off the objects, by means of which the spring force is overcome and the holding elements are brought into the pick up or drop off position. Once the objects have been inserted, the manual operation is released and the spring force moves the displaceable holding element against the fixed holding element in such a way that the objects are held.
  • the holding elements have bevels through which the at least one spring can be compressed when the objects are received. This eliminates manual operation when picking up the objects.
  • the holding elements can be designed in different ways, it can be two pins, bowl-shaped elements or elements that are adapted to the opening of the objects. It can also be provided that one of the holding elements is designed as a pin and the other as an opening, comb or web.
  • the principle of operation of a further embodiment can consist in the fact that the plate-like body and the actuating plate are designed as perforated plates, and have openings as receiving devices which are slightly larger than the objects, the perforated plates being displaceable such that the objects are offset by the openings can be held.
  • the perforated plates be arranged on both sides of the other perforated plate and thereby arranged twice.
  • the actuating device is expediently a lever mechanism with handles for one-hand operation, the lever mechanism for effecting a Force amplification is formed. This enables simple operation without great effort. However, this can also be achieved using wedges or threads.
  • the device has guides through which it can be brought into line with the grid of a carrier of pipette tips.
  • These guides can be arranged on the plate-like body wall elements, which can include the carrier. This makes it very easy to place the device on a carrier. It is neither necessary to thread the device into the pipette tips, nor is it necessary to thread the pipette tips into the receiving openings of the new carrier, since the guides in each case ensure an exact insertion. In this way, handling is particularly quick, simple and safe, the wall elements providing additional protection against contact and contamination of the pipette tips.
  • the second proposed removal and dispensing device which has an underside to which the objects adhere, can also be designed in a wide variety of ways. It is possible that the plate-like body can be detached in whole or in part after the objects have been transferred to the other carrier. The latter has the advantage that instead of the whole grid of objects, only a part of it can be transferred.
  • the plate-like body can consist of strips connected to one another in a hinge-like manner, as a result of which a number of objects can always be detached.
  • the design of the underside of the plate-like body can also be designed differently. It is possible that the underside is an adhesive surface or that the underside is such a plastic mass that the objects stick.
  • This liability must be such that it can be overcome after moving the objects into the other carrier to remove the plate-like body.
  • the underside has elastic receptacles that receive the objects. The recordings must then be shaped such that the objects can be inserted into and removed from them.
  • 7, 7a, 7b an embodiment with receiving openings that are adjustable in width
  • 11 and 11a an embodiment with openings and comb-shaped or web-shaped holding elements
  • Fig. 18 shows an embodiment with plastic or elastic mass
  • Fig. 1 shows a first embodiment in section and a carrier 31 which is equipped with pipette tips 1.
  • These pipette tips 1 are arranged in an 8 x 12 grid on the carrier 31 and are to be removed from there in order to place them on another carrier.
  • Such carriers 31 can be stacked one on top of the other in a tower, the pipette tips 1 of a carrier 31 engaging with their tips in the openings 2 of the pipette tips 1 of the carrier 31 underneath. These stacks are used for the transport and storage of a large number of pipette tips 1 in the smallest space.
  • the device for converting the pipette tips 1 consists of a plate-like body 3, on which receiving devices 5 are arranged in a grid 4, which corresponds to the grid 4 of the carrier 31.
  • the holding devices 5 consist of holding pins 8, which are formed by three elastic holding arms 12.
  • the receiving pins 8 have a diameter 9 ', which is slightly larger than the openings 2 of the pipette tips 1.
  • the elasticity and diameter 9 of the receiving pins 8 are dimensioned such that the pipette tips 1 can be plugged onto the receiving pins 8, clamp there, but without additional can be pushed back down.
  • the receiving pins 8 have chamfers 77 at their lower ends.
  • a stripper 19 which is designed as a grid-shaped perforated plate 20, is used to remove the pipette tips 1 such that each of its holes 21 surrounds a receiving pin 8.
  • This grid-shaped perforated plate 20 is slidably arranged, but held by means of brackets 42 in such a way that it cannot fall out. The device is placed on a support
  • the receiving pins 8 slide into the openings 2 of the pipette tips 1, and these clamp.
  • the scraper 19, which is designed as a grid-shaped perforated plate 20, is displaced upward in such a way that it leaves the receiving area 22 of the receiving pins 8 and thereby clears the way for receiving the pipette tips 1. So that the receiving pins 8 can be inserted into the openings 2 of the pipette tips 1 without problems, a guide is provided on the device, which consists of wall elements projecting perpendicularly from the plate-shaped body 3
  • a bevel 52 is used for better introduction. If necessary, springs can be provided which prevent the carrier 31 from becoming jammed in the device.
  • the plate-like body 3 is lifted off the carrier 31 again, all pipette tips 1 have been removed from the carrier 31 and are clamped onto receiving pins 8.
  • the plate-like body 3 is now placed on another carrier 31, this placement process in turn being facilitated by the wall elements 32.
  • the actuating device 10 is activated, which is designed as a lever mechanism 30. These are angular levers which have a long actuating arm and a short force transmission arm for the grid-shaped perforated plate 20. A pivot point is formed on the plate-like body 3 in the region of the bend.
  • FIG. 1 a shows a detail from FIG. 1, a pick-up pin 8 being shown, on which a pipette tip 1 is stuck.
  • the holding arms 12 are slightly compressed, the elastic holding force can be increased by an additional elastic body 33, which is placed between the holding arms 12.
  • the raster-shaped perforated plate 20 abuts the edges of its holes 21 against the upper ends of the pipette tips 1 and pushes them out of the receiving area 22 until the clamping in the opening 2 is released by the receiving pin 8 .
  • Fig. Lb shows the configuration of a receiving pin, which consists of three holding arms 12, which are arranged axially symmetrically and have the same shape.
  • the elastic body 33 is shown, which, if necessary, can increase the elastic holding force.
  • FIG. 1c shows an alternative embodiment of a receiving pin 8 which is mushroom-shaped 35, the head being divided into resilient areas which have a diameter 9 'which is slightly larger than the diameter 11 of the openings 2 of the pipette tips 1.
  • Fig. Id shows a further embodiment with a receiving pin 8, which has an elastic ring 73 for holding the objects 1.
  • FIG. 2 shows the possibility of a further embodiment on the basis of a receiving pin 8, in which resiliently designed holding arms 12 'are arranged such that the diameter 9 is somewhat smaller than the diameter 11 of the openings 2 of the pipette tips 1.
  • a pick-up pin 8 is inserted into the opening 2 of a pipette tip 1 and then an actuating device 10 'is started which, with an actuating rod 34, displaces an expansion body 13 within a wedge-shaped surface arrangement 14 lying between the holding arms 12' in such a way that the holding arms 12 'are spread outward in the direction of the arrows and the diameter of the receiving pin 8 increases so that it is larger than the diameter 11 of the openings 2 of the pipette tips 1.
  • Reference 9' stands for the larger diameter.
  • FIG. 3 shows holding arms 12 ", which form a receiving pin 8, which has a larger diameter 9 'than the diameter 11 of the openings 2 of the pipette tips 1.
  • the holding arms 12" can be compressed by moving an axially displaceable surround 15 by which To achieve diameter 9, which is smaller than the diameter 11 of the openings 2 of the pipette tips 1.
  • This receiving pin 8 can either be inserted into a pipette tip 1 by the displaceable surround 15 compressing the holding arms 12 "beforehand or by the receiving pin 8 is inserted into the opening 2 of a pipette tip 1 with such force that the holding arms 12 ′′ are compressed during insertion.
  • clamping is achieved in that the axially displaceable casing 15 is pushed up again, the holding arms 12 "spring outwards and hold the pipette tip 1.
  • the axially displaceable enclosures become 15 pushed back down by an actuating device 10, as a result of which the holding arms 12 ′′ are compressed in the direction of the arrows 44 and the pipette tips 1 are released.
  • the device is removed again while the pipette tips 1 remain on the carrier 31.
  • FIGS. 4 and 4a show a further embodiment using a receiving pin 8 made of an elastic body 18.
  • the elastic body 18 is located between a fixed surface 16, which is designed as a ring, which can be larger than the upper end of the pipette tips 1 and one Surface 17, which has a smaller diameter than the diameter 11 of the openings 2 of the pipette tips 1.
  • the second surface 17 is connected by means of an actuating rod 34 to an actuating device 10 ', this actuating rod 34 being passed through the elastic body 18 and the surface 16 is.
  • the receiving pin 8 can be inserted into a pipette tip 1 in order to then clamp it.
  • Fig. 5 shows an embodiment with externally engaging holding arms 24.
  • the plate-like body 3 is only equipped with short pick-up pins 8, which serve to better place picked-up pipette tips 1.
  • the pipette tips 1 are held after being picked up by elastic grippers 24 attacking on the outside.
  • Fig. 6 shows an embodiment with ejectors 25.
  • the Klemmkö ⁇ er 23 consists of a plate-like body 3 with receiving openings 29 which have a larger width than the diameter 51 of the pipette tips 1.
  • an ejector 25 is set in action by means of an actuating device 10 and removes the pipette tips 1 from the clamping body 23.
  • an embodiment is also conceivable in which the pipette tips 1 only hold by widening the receiving openings 29, the latter having a slightly smaller diameter than the diameter 51 of the pipette tips 1.
  • FIG. 7, 7a and 7b show an embodiment with receiving openings 29 which have an adjustable width 29 ', 29 ".
  • This embodiment consists of plates 26 and 27, between which a highly elastic body 28 is inserted.
  • the plate 27 and the strongly elastic bodies 28 have receiving openings 29 in a grid 4 which corresponds to that of a carrier 31.
  • These receiving openings have a width 29 which is larger than the outer diameter of the pipette tips 1. In this way the device, which is also equipped with wall elements 32 is placed over a carrier 31 which is equipped with pipette tips 1.
  • the lever mechanism 30' is equipped with long lever arms 37 which can be actuated by handles 36. These levers 37 are connected to the lower plate 27 by means of joints 38, angled short lever arms 39 being provided which press the plate 26 against the plate 27 when actuated.
  • the arrows 45 show the compression of the handles 36 and the arrows 46 the pressing of the elastic body 28 thereby triggered.
  • FIGS. 7a and 7b show the clamping and releasing of a pipette tip 1 by actuating and releasing the lever mechanism 30 '. Since the strongly elastic body 28 has sufficient resilient properties, it is sufficient to let go of the handles 36 so that they spring back again, the pipette tips 1 are released and the device is ready to receive pipette tips 1 again.
  • FIG. 8 shows an alternative embodiment of an actuating device 10 '. It is provided for embodiments in which a tensile force has to be applied, for example, to actuating rods 34 in order to clamp the pipette tips 1 firmly.
  • the actuating rods 34 are connected to one another by an actuating plate 47, and a lever mechanism 30 ′′ is arranged which has a joint 38 ′ on the actuating plate 47.
  • a force can be applied when the lever mechanism 30 ′ is actuated the plate-like body 3 and the actuating plate 47 are separated from one another and thereby act upon the actuating rods 34 with tension in order to effect the clamping of the pipette tips 1 for exemplary embodiments as shown in Fig.
  • a additional spring 48 or 48 ' can be provided to facilitate the actuation by additional spring force application. It can be tension or compression springs, depending on whether one direction of adjustment or the other is to be supported. In solid lines there is one Possibility of attaching a spring 48 shown, the dash-dotted lines 50 show a alternative attachment of a spring 48 '. With all actuating devices 10, 10 'and 10 ", care must be taken that the forces act evenly in order to bring about a parallel displacement of the scraper 19, an actuating plate 47 or a plate 26. It is therefore expedient for levers such as 39 and 39' to grip. either on two longitudinal sides of the plate 20, 26, 47 to be moved or they are arranged such that they each act in the four corner regions of the plates 20, 26, 47.
  • actuating devices are only to be regarded as an example; of course, instead of a lever mechanism, another actuation option is also conceivable, including hydraulic, electrical or pneumatic actuation. The latter will be used in particular if the device is integrated in an automatic machine.
  • FIG. 9 and 9a show an embodiment of the invention with displaceable perforated plates 63 and 64.
  • the perforated plate 63 is stationary, that is to say as a plate-like body, and the perforated plate 64 is designed as a displaceable actuating plate.
  • the perforated plates 63, 64 have openings 65, 66 with a slightly larger diameter than the objects 1, which are drawn here as pipette tips. If these openings 65, 66 are exactly aligned, as shown in FIG. 9a, the objects 1 can be picked up or released. The latter is shown by arrow 75. With such aligned openings 65, 66, objects 1 are received by a carrier by being inserted into the openings 65, 66 with the region of their cylindrical outer wall.
  • the perforated plate 64 is displaced in the direction of the arrow 74, as is shown in FIG. 9. So that the objects 1 are held exactly vertically, the perforated plate 63 is arranged twice and on both sides of the perforated plate 64.
  • FIG. 10 shows another embodiment in which the holding elements 57, 58 are designed as openings 68 and pins 67. These pins 67 can also have the shape of receiving pins 8 in order to better guide the objects 1.
  • the perforated plate 64 serving as the actuating plate can be displaced in the direction of the double arrow 62, as a result of which objects 1 can be clamped or released between the openings 68 and the pin 67 with their walls 53.
  • Fig. 11 shows an embodiment in which the pin 67 with a comb-shaped
  • the comb-shaped holding element can be designed as a fixed 57 or as a displaceable holding element 58.
  • the cones are corresponding
  • 11a shows a similar embodiment, in which the holding element 57 or 58 as
  • FIG. 12 shows an embodiment with a displaceable actuating plate 56 and the holding elements 57 and 58 which grip the object 1 in its opening 2.
  • the object 1 is a test tube.
  • the fixed holding element 57 is connected to the plate-like body 3, and the displaceable holding element 58 with the actuating plate 56, which can be moved in the direction of the double arrow 62.
  • Fig. 12 shows the position in which the sample tube 1 is held.
  • 12a shows the working state in which the objects 1 can be picked up or released.
  • FIG. 12b also shows an expedient arrangement of the holding elements 57 and 58, the fixed holding element 57 consisting of two pins and the displaceable holding element 58 consisting of one pin.
  • the double arrow and the dash-dotted representation of the displaceable holding element 58 indicate the actuation. With this embodiment, three breakpoints are reached on the object 1 so that it is held securely in its position.
  • the internally engaging holding element 55 can be designed as a receiving pin 8 for safe guiding of the object 1.
  • FIG. 13 and 13a show rounded, concentrically arranged holding elements designed as clamping bodies 23, 23 '.
  • Objects 1 can be plugged onto holding elements 23 or onto holding elements 23 ', whereby objects of different diameters can be held. This is shown in Fig. 13a. It is also possible that objects 1 can also be inserted in the spaces between four arrangements of clamping elements 23 ', as shown in FIG. 13.
  • ejectors 25 are provided, 2 ⁇ which, coming from the direction of the plate-like body 3, strip the objects 1 from the clamping bodies 23, 23 '.
  • FIG. 15 and 15a show a side view of how the concentric holding elements 23, 23 'and 23' "can accommodate different sizes of objects 1.
  • Fig. 15a shows several objects 1 of different sizes.
  • a receiving device takes 5 shows only one object 1 in one of the sizes
  • Fig. 15a shows how an ejector 25 removes the object 1 by means of an actuating device 10.
  • 16 and 16a shows holding elements 57 and 58 which engage on the inside, with bevels 59 for the introduction of the objects 1.
  • a displaceable holding element 58 is connected to the displaceable actuating plate 56 and the fixed holding element 57 is connected to the plate-like body 3.
  • a spring 60 is arranged between the plate-like body 3 and the displaceable actuating element 56, which generates the holding force for the objects 1. If the objects 1 are to be picked up, the removal and dispensing device is only to be pressed against the carrier 31 with the objects 1, since the holding elements 58 and 57 move by means of the bevels 59 when the objects 1 are inserted into their holding position 6, in which they are held by the holding force of the spring 60.
  • 16a shows a section XVIa through FIG. 16.
  • the bevels 59 are arranged in such a way that there is a frustoconical roof surface onto which the objects 1 can be easily pushed.
  • 16b shows a corresponding exemplary embodiment with the difference that the holding elements 57 and 58 engage on the outside and accordingly the bevels 59 are arranged differently.
  • the plate-like body 69 having an adhesive layer in the form of an adhesive layer 76 to which the objects 1 adhere, from which, however, it can be detached again after being placed on the new carrier 31.
  • FIG. 18 A similar embodiment is shown in FIG. 18, wherein a plate-like body 71 is provided with an elastic mass which has receptacles 72 shaped in such a way that objects 1 can be inserted, are held, but can also be detached again after being placed on a carrier 31.
  • An alternative is a plate-like body 71 'which has a plastic mass, by means of which the shape 72 of the elastic mass just described and illustrated is produced by pressing it onto the objects 1 in the plastic mass. The required holding force is also applied by this design 72.
  • the advantage of the plastic mass is that such a device can always be used regardless of the shape and size of the objects.
  • 19 and 20 show the detachment of a plate-like body 69, 71 or 71 'after the objects 1 have been placed on a carrier 31. It is possible that the plate-like body 69, 71 or 71' is either folded away in strips 70 in order to To release rows of objects 1, or as shown in Fig. 19, to release portions 70 is bent upwards.
  • Removal and delivery device for objects for laboratory use which at least partially have a hollow cylindrical contour
  • Actuating plate, 48 'spring (pull or push)
  • Double arrow displacement of the holding element 58

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un dispositif de saisie et de distribution d'objets utilisés en laboratoire au moins partiellement de forme cylindrique creuse, tels que pointes de pipettes, éprouvettes, récipients de réactifs ou cuvettes. Le dispositif comprend un corps plat (3, 26, 63) pourvu de dispositifs de saisie (5) conçus et agencés de façon à pouvoir saisir des objets (1) réunis sur un premier support (31) avec leur ouverture (2) vers le haut selon une grille normalisée de haute densité et les transférer sur un autre support (31). Une plaque d'actionnement (15, 20, 27, 47, 56, 64) s'étend sur la zone des dispositifs de saisie (5), parallèlement au corps plat (3, 26), et peut être déplacée par rapport au corps plat (3, 26, 63) au moyen d'un dispositif d'actionnement (10, 10', 10''). Les dispositifs de saisie (5) peuvent ainsi être mis dans trois états de fonctionnement (6, 7, 8'). Dans un premier état de fonctionnement (7), les dispositifs de saisie (5) peuvent saisir les objets (1), dans un deuxième état de fonctionnement (6), il peuvent les serrer, et dans un troisième état de fonctionnement (7'), ils peuvent les libérer.
EP98922637A 1997-04-05 1998-04-03 Dispositif de saisie et de distribution d'objets utilises en laboratoire au moins partiellement de forme cylindrique creuse Withdrawn EP1007211A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19714135A DE19714135C1 (de) 1997-04-05 1997-04-05 Vorrichtung zum Umsetzen von Gegenständen für Laborbedarf
DE19714135 1997-04-05
DE19722667 1997-05-30
DE19722667 1997-05-30
PCT/EP1998/001950 WO1998045041A1 (fr) 1997-04-05 1998-04-03 Dispositif de saisie et de distribution d'objets utilises en laboratoire au moins partiellement de forme cylindrique creuse

Publications (1)

Publication Number Publication Date
EP1007211A1 true EP1007211A1 (fr) 2000-06-14

Family

ID=26035519

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98922637A Withdrawn EP1007211A1 (fr) 1997-04-05 1998-04-03 Dispositif de saisie et de distribution d'objets utilises en laboratoire au moins partiellement de forme cylindrique creuse

Country Status (2)

Country Link
EP (1) EP1007211A1 (fr)
WO (1) WO1998045041A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6286678B1 (en) * 1999-03-05 2001-09-11 Rainin Instruments Co., Inc. Refill pack for pipette tip racks and improved pipette tip support plate for use in such packs and racks
EP3459635B1 (fr) * 2008-04-11 2021-03-03 Biotix, Inc. Dispositifs de manipulation de pointe de pipette
US8590736B2 (en) 2009-04-11 2013-11-26 Biotix, Inc. Automated pipette tip loading devices and methods
CN105344407B (zh) * 2015-10-16 2017-09-26 浙江省海洋水产研究所 一种高通量浮动式试管安装装置
CN113877648B (zh) * 2021-08-26 2023-02-24 湖南伊鸿健康科技有限公司 一种加样装置
CN114178059B (zh) * 2021-11-23 2023-10-03 辽阳友信制药机械科技有限公司 一种血液科病人血液分层离心设备

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US4478094A (en) * 1983-01-21 1984-10-23 Cetus Corporation Liquid sample handling system
US5324482A (en) * 1992-08-27 1994-06-28 David A. White Pipette tip packaging system
GB9300200D0 (en) * 1993-01-07 1993-03-03 Unilever Plc Article handling
SE500962C2 (sv) * 1993-07-08 1994-10-10 Lars Erik Trygg Flaskgripare
DE9310258U1 (de) * 1993-07-09 1993-08-26 Carl Roth GmbH & Co, 76185 Karlsruhe Verpackungseinheit für Pipettenspitzen
DE4419291C2 (de) * 1994-06-02 1996-11-21 Bernd Dr Steinbrenner Pipettenspitzen- und Einwegreaktionsgefäße-Bereitstellungs- und Entnahmevorrichtung
US5588792A (en) * 1995-03-16 1996-12-31 Tiso; Allan Pipette tip rack loader

Non-Patent Citations (1)

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Title
See references of WO9845041A1 *

Also Published As

Publication number Publication date
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