EP0998979B1 - Appareil de dosage électronique - Google Patents

Appareil de dosage électronique Download PDF

Info

Publication number
EP0998979B1
EP0998979B1 EP99120596A EP99120596A EP0998979B1 EP 0998979 B1 EP0998979 B1 EP 0998979B1 EP 99120596 A EP99120596 A EP 99120596A EP 99120596 A EP99120596 A EP 99120596A EP 0998979 B1 EP0998979 B1 EP 0998979B1
Authority
EP
European Patent Office
Prior art keywords
supply voltage
metering device
electronic metering
drive
voltage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP99120596A
Other languages
German (de)
English (en)
Other versions
EP0998979A3 (fr
EP0998979A2 (fr
Inventor
Matthias Baumgartner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7886388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0998979(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eppendorf SE filed Critical Eppendorf SE
Publication of EP0998979A2 publication Critical patent/EP0998979A2/fr
Publication of EP0998979A3 publication Critical patent/EP0998979A3/fr
Application granted granted Critical
Publication of EP0998979B1 publication Critical patent/EP0998979B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227—Details of motor drive means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED

Definitions

  • the invention relates to an electronic dosing device.
  • Dosing devices are used in the laboratory for dosing liquids. They are known in different versions. Dosing devices operating according to the air-cushion principle have an integrated piston-cylinder unit by means of which an air column can be displaced in order to suck sample liquid into a tip of the dose and eject it out of it. In this case, the piston-cylinder unit does not come into contact with the liquid. Only the dosing tip, which is usually made of plastic, is contaminated and can be replaced after use.
  • a syringe In direct displacement metering, however, a syringe is filled directly with sample liquid. Piston and cylinder of the syringe are so contaminated by the liquid, so that the syringe usually has to be replaced or cleaned by a new syringe before changing the liquid.
  • the syringe is usually made of plastic.
  • Non-piston metering devices may include a metering tip having a balloon-like end portion which expands to suck in liquid and is compressed for ejection. Such metering tips have also been designed as a replacement part.
  • Air-cushion, direct-displacement, piston-less and micro-metering devices may have a fixed or variable metering volume.
  • a change in the dosing volume is achieved by adjusting the displacement of the displacer, i. the displacement of the piston or the degree of deformation of the balloon-like end portion or the chamber wall.
  • Dispensers are dosing devices that can deliver a recorded volume of liquid repetitively in small quantities.
  • All metering devices can be designed in particular as a handheld device and / or stationary devices.
  • All of the aforementioned metering devices may be electronic metering devices in the sense of this application. They have a drive device with an electric drive for driving a displacement device which may be the piston-cylinder unit or the balloon-like end portion of a metering tip or a deformable wall chamber.
  • the electric drive may in particular be an electric drive motor, electric linear drive or one of the electric drives mentioned in connection with the microdosing devices.
  • an electronic control device for the drive and an electrical voltage source for the supply of control device and drive is present.
  • Electronic metering devices have the particular advantage of high reproducibility of dosages. In particular, by preset constant metering speeds ( ⁇ l / s) more accurate results can be achieved than with manually driven metering devices. In addition, they have the advantage of a wide range of applications as they can perform both simple pipetting functions and dispenser functions.
  • the electrical voltage source may include a battery, a rechargeable battery and / or a power supply.
  • US 4671123 discloses an elecktronische metering device with an electric drive proving drive means, at least one driven by the drive means displacement means for metering fluid and an electrical voltage source for the electric drive
  • the electrical power source is dimensioned to provide sufficient power in the normal state for driving at all operating loads of the drive device.
  • a battery or a rechargeable battery this requires a corresponding number of cells.
  • the discharge progresses and supply voltage drops, it can increasingly lead to malfunctions.
  • the drive means With decreasing supply voltage namely decreases the torque of the drive, so that the drive means no longer drives the displacement means at all occurring loads in the desired manner.
  • steps can be lost and dosing errors thereby arise. That is why for reliable operation Over a desired time a complex battery or rechargeable battery supply with appropriate costs, volume and weight required. The same applies to the execution of the electrical voltage source as a power supply.
  • the present invention seeks to provide an electronic dosing device, in which the cost of the electrical voltage source, in particular their cost, space and weight, is reduced and the drive is still supplied with the required voltage at all operating loads.
  • the control and / or regulating device provides the drive via a converter with a supply voltage which is matched to the respective load of the drive device. For example, she can increase the supply voltage at the beginning of a drive operation to overcome starting resistances of the displacement device. Thereafter, it can lower the supply voltage to a nominal value which is sufficient for a further drive of the displacer displaced in motion. If the metering device can be equipped with different displacement devices that represent different loads for the drive devices, for example syringes of different sizes, the supply voltage can be matched to the respective displacement device.
  • the control and / or regulating device controls the operation of the metering device, for example, according to control commands that can be entered via a keyboard, so that it knows the respective operating state of the metering device. According to predetermined criteria, the control and / or regulating device can find out a suitable supply voltage for each operating state and make it available via the converter. In addition, information about the respective existing displacement device, for. As a coding of a syringe, automatically read from the metering device or entered separately. Furthermore, the control and / or regulating device can determine the respective load, which can be changed unpredictably by external influences, and regulate the supply voltage on the basis of the result of the determination. Thus, the vote of the supply voltage to the respective load can be achieved.
  • the invention is not limited to the use of an up-converter. Also included is the case where the supply voltage required by the electric drive is below the supply voltage of the power supply. For example, lithium-ion (Li-ion) batteries are available, which provide a relatively high voltage (about 3V per cell), so that By series connection only a few cells a relatively high supply voltage can be provided. In the prior art is - especially when using stepper motors - at low load of the drive device, the high supply voltage partially converted into heat loss. This is undesirable for several reasons. In the context of the invention, a down-conversion of the supply voltage to a supply voltage with the level required at the respective load can now take place in such cases. Also included in the invention is the case that the supply voltage from the converter both up and down, depending on the load of the drive means.
  • the dosing device has the advantage that the electrical voltage source and the drive can be tuned to an average load. At increased loads, the converter provides an increased supply voltage. Since these occur only briefly, no damage to the drive motor is to get. As a result, the metering device comes with a smaller number of battery or rechargeable battery cells or a smaller sized power supply than conventional metering devices. On the part of the electrical voltage source, a cost saving can be achieved which exceeds the additional costs for the converter. In addition, this reduces the space required for the voltage source and achieved a weight reduction of the metering device. Another advantage is that the converter at the same time allows control of the supply voltage, so that it is largely independent of EndladungsSullivan a battery or a rechargeable battery.
  • the electric drive can in particular be an electric drive motor, an electric linear drive or one of the associated with microdosing be mentioned electrical drives.
  • An electric drive motor may in particular be a stepping motor in which a pulse control favors precisely defined metering quantities or metering steps.
  • precisely defined dosing quantities can be ensured in particular by end stops, angle encoders or coding strips.
  • the drive means may have a gear for converting a rotational movement of a shaft of a drive motor into a linear drive motion for the displacement means.
  • the displacement device has a piston-cylinder arrangement. This can be the syringe of a direct displacer or the displacement unit of an air cushion metering device.
  • the electrical voltage source may have at least one battery, at least one battery and / or a power supply.
  • NiMH batteries may be present.
  • a supply voltage of 2.4 volts is provided by two such batteries.
  • the converter can supply the supply voltage approximately at the level of the supply voltage and above.
  • the supply voltage in the amount of a supply voltage of z. B. 2.4 volts are used to exert a holding torque on a stepper motor, which is limited to a nominal voltage of z. B. 6 volts is designed.
  • a holding torque there is a tendency for the stepping motor to decelerate during deceleration, so that it may still travel one or more undesired steps.
  • the converter may supply the supply voltage at various discrete or continuous levels. Of these, one of the generation of a holding torque can serve. Another level may be the nominal voltage required by the drive motor at average load. In addition, there may be an increased stress level for increased loads. Accordingly, the control device can supply the supply voltage at the low level when the drive motor is stopped, at the average level during average load, and at the elevated level when the load is increased. For example, the supply voltage may assume the discrete values of 2.4 volts, 6 volts and 8 volts.
  • the converter has a boost converter.
  • Step-up converters are circuits known in the field of supply technology with which a DC voltage can be brought to a higher level. Step-up converters can provide an output voltage above the input voltage, typically exploiting the energy stored in an inductor.
  • the electronic dosing device is designed as a handheld device and accordingly equipped with at least one battery or at least one accumulator.
  • the electronic pipetting device consists essentially of six Funtions Schemee, namely a drive device 1, a displacement device 2, an electronic control and / or regulating device 3, an electrical voltage source 4, an operating device 5 and a display device 6. All functional areas 1 to 6 are in or on a - not shown - designed pipette housing a hand pipette.
  • the drive device 1 has an electric drive motor, which is designed as a stepper motor 7. By means of the stepping motor 7, an axis 8 is linearly displaceable back and forth.
  • the drive device includes an engine stage in the form of two H-bridges 9, which serves to control the stepping motor 7. This includes in a manner known to those skilled in eight H-connected power transistors with which the stepper motor 7 can be operated via supply lines 10 in the forward and reverse directions.
  • the displacement device 2 has a piston 11 which is fixed to the axis 8.
  • the piston 11 is displaceable in a cylinder 12. This is connected via a channel 13 with a pipette tip 14 which is separable from the device.
  • the electronic control and / or regulating device 3 includes a microcontroller 15, which has in particular a timer, a working memory and a non-volatile memory integrated.
  • the microcontroller controls the H-bridges via control lines 16.
  • Another component of the control and / or regulating device 3 is a further boost converter 20, which supplies the microcontroller 15 via further supply lines 21.
  • the axis 8 of the stepping motor 7 is associated with a repository switch 22 which is monitored by a control line 23 from the microcontroller 15 to allow a zero point adjustment.
  • the electrical voltage source 4 comprises two NiMH batteries 24, the supply voltage via feed lines 25 to the up-converter 17 and the other boost converter 20 is supplied.
  • the supply voltage of the two batteries 24 is supplied via control lines 26 to the microcontroller 15.
  • the electric voltage source 24 includes a charging current control 27, which is connected on the one hand via charging contacts 28 with an external power source and on the other hand is connected via charging lines 29 to the battery 24.
  • the charge current controller 27 is also connected to the microcontroller 15 via control lines 30 for the charging voltage and via charging current control lines 31, respectively.
  • the operating device 5 comprises an input keyboard 32, which is connected via lines 33 to the microcontroller 15. It also includes release buttons 34, which is connected via lines 35 to the microcontroller 15.
  • the display device 6 is an LCD display, which is connected via lines 36 to the microcontroller 15, which contains a display control.
  • the pipetting device works as follows:
  • the control software is stored in the microcontroller 15. Special pipetting parameters may be entered before dosing by means of the input keyboard 32. By means of the release buttons 34 individual pipetting operations can be triggered.
  • the display 6 displays input pipetting parameters, control commands and operating states of the pipetting device.
  • the total supply voltage of the two battery cells 24 is 2.4 volts. This is regulated by the further boost converter 20 to 3.3 volts supply voltage for the microcontroller 15.
  • the boost converter 17 switches the supply voltage of the battery 24 as a supply voltage to the supply lines 18 or increases it to 6 or 8 volts. Since the microcontroller controls the operation of the stepper motor 7 via the control lines 16, it knows its respective voltage requirement and controls the boost converter 17 accordingly.
  • the supply voltage is controlled by the microcontroller 15 via the control lines 26. If it falls below a permissible value, the display 6 outputs a corresponding information. By connecting the charging contacts 28 to an external power supply can be done in case of need, a charge of the battery 24. About the charging current control lines 31, the charging current is controlled according to the determined via the control lines 30 state of charge of the battery 24.
  • the boost converter 17 comprises an IC 37 of the type known in the art as a boost converter.
  • the example is the IC MAX 608 from Maxim.
  • the IC 37 is connected in the usual way with transistor 38, resistor 40, capacitors 45 to 50, diode 51 and inductance 52.
  • the IC 37 controls via the voltage feedback consisting of transistor 39 and resistors 41 to 43, the duty cycle of the transistor 38, whereby the inductance 52 is charged with energy. This energy is delivered as an additional series voltage source during the blocking phase of the transistor 38 to the output capacitors 48 and 49.
  • the voltage feedback can be switched by means of the contact 57. If the contact 57 is set to "low”, the supply voltage is 6V; if it is set to "high”, it is 8V.
  • the feeders 25 are connected to the contacts 53, 54 and the supply lines 18 to the contacts 55, 56 and the control lines 19 to the contacts 57, 58 are connected.
  • U A is the supply voltage and U E is the supply voltage.
  • t1 is the time during which the transistor 38 is conducting and t2 is the time during which the transistor 38 is off. If transistor 38 conducts for as long as it blocks, then U a ⁇ 2 x U e . On the other hand, if the transistor blocks the whole time, U a ⁇ U e .
  • the increase in the torque of the drive motor 7 results from the fixed motor internal resistance and the raised driving voltage U A.
  • the electrical power that is converted in the engine is also a measure of the available engine torque.
  • the Fig. 3 illustrates the principle of operation of the invention.
  • An electrical voltage source 24 in the form of a battery, a rechargeable battery or a power supply provides a low supply voltage to a boost converter 17.
  • This is controlled digitally or analogue by means of control lines 19 via the voltage factor N u and accordingly supplies a supply voltage according to the product of the voltage factor N u and the supply voltage.
  • This supply voltage drives the drive motor 7 via the motor output stage 9.
  • a continuous variation of the voltage factor N u is possible in order to achieve a fine adjustment to the power requirement.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Charge And Discharge Circuits For Batteries Or The Like (AREA)
  • Control Of Stepping Motors (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Dc-Dc Converters (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)

Claims (15)

  1. Appareil de dosage électronique comprenant
    - un dispositif d'entraînement (1) présentant un entraînement électrique (7),
    - au moins un dispositif de déplacement (2) pouvant être entraîné par le dispositif d'entraînement (1) pour le pipettage de liquide et
    - un dispositif de commande et/ou de contrôle électronique (3) pour le moteur d'entraînement (7) avec un convertisseur (17), qui transforme une tension d'alimentation fournie par une source de tension électrique (24) en une tension de fonctionnement pour le moteur d'entraînement (7) accordée en hauteur à la charge respective du dispositif d'entraînement (1), le convertisseur (17) fournissant la tension de fonctionnement environ au même niveau que la tension d'alimentation et au-dessus.
  2. Appareil de pipettage électronique selon la revendication 1, dans lequel le moteur d'entraînement électrique est un moteur pas à pas (7).
  3. Appareil de pipettage électronique selon la revendication 1 ou 2, dans lequel le dispositif d'entraînement (1) présente un mécanisme de transmission pour transformer un mouvement rotatif d'un arbre du moteur d'entraînement (7) en un mouvement d'entraînement linéaire pour le dispositif de déplacement (2).
  4. Appareil de pipettage électronique selon l'une des revendications 1 à 3, dans lequel le dispositif de déplacement (2) présente un ensemble piston-cylindre (11, 12) qui est constitué en tant que seringue pour la réception du liquide à pipetter ou qui est relié à une pointe de pipette (14) par un canal (13) pour la réception du liquide à pipetter.
  5. Appareil de pipettage électronique selon l'une des revendications 1 à 4, dans lequel la source de tension électrique présente au moins une pile, au moins un accu (24) et/ou un bloc secteur.
  6. Appareil de pipettage électronique selon la revendication 5, dans lequel l'alimentation en courant électrique (2) présente par exemple des accus NiMH (24), des accus NiCd ou des accus Li-ion.
  7. Appareil de pipettage électronique selon l'une des revendications 1 à 6, dans lequel le convertisseur (17) fournit également une tension de fonctionnement accordée en hauteur à la charge respective du dispositif d'entraînement (1) en-dessous du niveau de la tension d'alimentation.
  8. Appareil de pipettage électronique selon l'une des revendications 1 à 7, dans lequel le convertisseur (17) fournit la tension de fonctionnement à des niveaux discrets ou variables différents.
  9. Appareil de pipettage électronique selon la revendication 8, dans lequel le convertisseur (17) fournit la tension de fonctionnement à trois niveaux différents.
  10. Appareil de pipettage électronique selon la revendication 8 ou 9, dans lequel le convertisseur (17) fournit la tension de fonctionnement au moins aux niveaux de 2,4 volts, 6 volts et 8 volts.
  11. Appareil de pipettage électronique selon l'une des revendications 8 à 10, dans lequel le dispositif de commande (1) fournit la tension de fonctionnement lors de l'arrêt du moteur d'entraînement (7) à un niveau bas, lors d'une charge normale du dispositif d'entraînement (1) à un niveau moyen et lors d'une charge élevée du dispositif d'entraînement (1) à un niveau élevé.
  12. Appareil de pipettage électronique selon l'une des revendications 1 à 11, dans lequel le convertisseur (17) présente un convertisseur-élévateur (37).
  13. Appareil de pipettage électronique selon la revendication 12, dans lequel le convertisseur (17) présente une inductance (32).
  14. Appareil de pipettage électronique selon l'une des revendications 1 à 13, dans lequel le dispositif de commande (3) commande le moteur d'entraînement électrique (7) par des montages en pont (9).
  15. Appareil de pipettage électronique selon l'une des revendications 1 à 14, qui est un appareil de pipettage portatif.
EP99120596A 1998-11-02 1999-10-16 Appareil de dosage électronique Expired - Lifetime EP0998979B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19850417 1998-11-02
DE19850417A DE19850417C2 (de) 1998-11-02 1998-11-02 Elektronische Dosiervorrichtung

Publications (3)

Publication Number Publication Date
EP0998979A2 EP0998979A2 (fr) 2000-05-10
EP0998979A3 EP0998979A3 (fr) 2002-04-10
EP0998979B1 true EP0998979B1 (fr) 2008-06-11

Family

ID=7886388

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99120596A Expired - Lifetime EP0998979B1 (fr) 1998-11-02 1999-10-16 Appareil de dosage électronique

Country Status (4)

Country Link
US (1) US6499365B1 (fr)
EP (1) EP0998979B1 (fr)
JP (1) JP4981200B2 (fr)
DE (2) DE19850417C2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE499989T1 (de) 2000-12-18 2011-03-15 Protedyne Corp Extrudieren von gel für gel elektrophorese
DE102004016003B4 (de) * 2004-04-01 2006-05-04 Eppendorf Ag Elektronische Pipette
CN102735305B (zh) * 2012-06-19 2014-05-07 浙江大学 一种伺服电机控制的燃料测量装置
CN107847929B (zh) 2015-06-05 2020-08-11 米梅塔斯私人有限公司 微流体板
CN113908899B (zh) * 2021-09-17 2023-05-02 圣湘生物科技股份有限公司 移液装置、核酸提取、检测装置及移液器更换方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018362A (en) * 1975-11-06 1977-04-19 Union Chimique Continentale-U.C.C. Automatic control for liquid flow
US4071168A (en) * 1976-04-22 1978-01-31 Pettibone Corporation Level control system for a rotary cone-type feed hopper
CA1105956A (fr) * 1978-01-09 1981-07-28 William J. Bourne Applicateur de substances granulaires
US4232255A (en) * 1978-11-06 1980-11-04 Carlen Eric T Delivery control system for vehicle-mounted spreader
US4475666A (en) * 1981-08-31 1984-10-09 American Hospital Supply Corporation Automated liquid dispenser control
US4671123A (en) * 1984-02-16 1987-06-09 Rainin Instrument Co., Inc. Methods and apparatus for pipetting and/or titrating liquids using a hand held self-contained automated pipette
US4616305A (en) * 1985-02-11 1986-10-07 Eaton Corporation AC/DC power MOSFET reversing H-drive system
US4964533A (en) * 1985-03-18 1990-10-23 Isco, Inc. Pumping system
DE3531241A1 (de) * 1985-08-31 1987-03-05 Eppendorf Geraetebau Netheler Vorrichtung zur gesteuerten ausgabe von fluessigkeiten
US4988481A (en) * 1989-01-30 1991-01-29 Labsystems Oy Electrical pipette
CH678926A5 (fr) * 1989-04-04 1991-11-29 Mettler Toledo Ag
JPH03188326A (ja) * 1989-12-19 1991-08-16 Aisan Ind Co Ltd 電子式定量止水栓
FI87740C (fi) * 1990-05-04 1994-04-08 Biohit Oy Pipett
GB9119448D0 (en) * 1991-09-12 1991-10-23 Vickers Systems Ltd System controls
US5269353A (en) * 1992-10-29 1993-12-14 Gilbarco, Inc. Vapor pump control
JP3188326B2 (ja) 1992-11-06 2001-07-16 有限会社美濃資源開発 溶融スラグの高級資源化方法および低温窯業焼結体の製造方法
JPH08223993A (ja) * 1995-02-16 1996-08-30 Canon Inc ステップモータの駆動制御装置
US5840346A (en) * 1995-05-26 1998-11-24 Hannaford; Christopher S. Viscous material dispensing apparatus
JP3648326B2 (ja) * 1996-05-22 2005-05-18 アロカ株式会社 ピペット装置
JP3694755B2 (ja) * 1996-07-22 2005-09-14 アークレイ株式会社 ピペッティング方法、ピペッティング装置、および記憶媒体
US5992686A (en) * 1998-02-27 1999-11-30 Fluid Research Corporation Method and apparatus for dispensing liquids and solids
US6254832B1 (en) * 1999-03-05 2001-07-03 Rainin Instrument Co., Inc. Battery powered microprocessor controlled hand portable electronic pipette

Also Published As

Publication number Publication date
DE19850417A1 (de) 2000-05-11
JP2000146663A (ja) 2000-05-26
EP0998979A3 (fr) 2002-04-10
EP0998979A2 (fr) 2000-05-10
DE59914784D1 (de) 2008-07-24
DE19850417C2 (de) 2002-08-08
US6499365B1 (en) 2002-12-31
JP4981200B2 (ja) 2012-07-18

Similar Documents

Publication Publication Date Title
EP0390253B1 (fr) Dispositif chargeur pour appareils électriques munis d'accumulateurs
EP1598113B1 (fr) Pipette
EP2283927B1 (fr) Appareil électrique de dosage pour liquide
DE60120891T2 (de) Piezoaktor-Ansteuervorrichtung mit Funktion zur Detektion von Abweichungen
EP0095072B1 (fr) Dispositif d'alimentation à commutation électronique
EP0999432B2 (fr) Procédé d' opération d' un système de dosage électronique et système de dosage pour la mise en oeuvre du procédé
EP2292330A1 (fr) Dispositif de dosage électronique destiné au dosage de liquides
EP0998979B1 (fr) Appareil de dosage électronique
WO2009135824A1 (fr) Procédé et dispositif permettant de commander une servocommande
EP1825123B1 (fr) Circuit electrique pour reguler un element piezo-electrique, notamment un systeme d'injection de carburant d'automobile
DE60027829T2 (de) Ansteuerschaltung für piezoelektrische/elektrostriktive Bauelemente
DE10301343B4 (de) Dosiervorrichtung
DE102004003838B4 (de) Schaltungsanordnung zum Aufladen und Entladen von mehreren kapazitiven Stellgliedern
EP1825529B1 (fr) Circuit electrique pour reguler un element piezo-electrique, notamment d'un systeme d'injection de carburant d'automobile
DE19861339B4 (de) Elektronische Handpipettiervorrichtung
DE102004030249A1 (de) Piezoaktor-Ansteuerschaltung zur Aufladung und Entladung eines Piezoaktors
DE102004026250B4 (de) Ansteuerschaltung für Piezoaktoren
EP1302990A2 (fr) Méthode de commande d'un actionneur piézoélectrique et actionneur correspondant
EP0183981B1 (fr) Dispositif de clouage ou d'agrafage entraîné par une batterie
DE10113801B4 (de) Vorrichtung zum Ansteuern wenigstens eines kapazitiven Stellgliedes und Verfahren zum Betreiben einer solchen Vorrichtung
DE19944249B4 (de) Vorrichtung zum Ansteuern wenigstens eines kapazitiven Stellgliedes
DE19653666A1 (de) Verfahren zum schnellen Ansteuern kapazitiver Lasten
WO1994014229A1 (fr) Regulation automatique de retour du courant sous charge
DE3323747A1 (de) Elektronisches schaltnetzteil
EP0932927B1 (fr) Appareil de commande avec reduction du courant de repos

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Kind code of ref document: A2

Designated state(s): CH DE FI FR GB LI

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: EPPENDORF AG

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

17P Request for examination filed

Effective date: 20020502

AKX Designation fees paid

Free format text: CH DE FI FR GB LI

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): CH DE FI FR GB LI

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REF Corresponds to:

Ref document number: 59914784

Country of ref document: DE

Date of ref document: 20080724

Kind code of ref document: P

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: ISLER & PEDRAZZINI AG

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20090312

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 17

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 18

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 19

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20181019

Year of fee payment: 20

Ref country code: FI

Payment date: 20181022

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20181019

Year of fee payment: 20

Ref country code: CH

Payment date: 20181019

Year of fee payment: 20

Ref country code: FR

Payment date: 20181022

Year of fee payment: 20

REG Reference to a national code

Ref country code: DE

Ref legal event code: R071

Ref document number: 59914784

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Expiry date: 20191015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20191015