EP0988371A4 - Human tumor necrosis factor receptor tr9 - Google Patents

Human tumor necrosis factor receptor tr9

Info

Publication number
EP0988371A4
EP0988371A4 EP19980926471 EP98926471A EP0988371A4 EP 0988371 A4 EP0988371 A4 EP 0988371A4 EP 19980926471 EP19980926471 EP 19980926471 EP 98926471 A EP98926471 A EP 98926471A EP 0988371 A4 EP0988371 A4 EP 0988371A4
Authority
EP
European Patent Office
Prior art keywords
necrosis factor
tumor necrosis
factor receptor
human tumor
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19980926471
Other languages
German (de)
French (fr)
Other versions
EP0988371A1 (en
Inventor
Jian Ni
Guo-Liang Yu
Ping Fan
Reiner L Gentz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0988371A1 publication Critical patent/EP0988371A1/en
Publication of EP0988371A4 publication Critical patent/EP0988371A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
EP19980926471 1997-06-11 1998-06-10 Human tumor necrosis factor receptor tr9 Withdrawn EP0988371A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5299197P 1997-06-11 1997-06-11
US52991P 1997-06-11
PCT/US1998/011932 WO1998056892A1 (en) 1997-06-11 1998-06-10 Human tumor necrosis factor receptor tr9

Publications (2)

Publication Number Publication Date
EP0988371A1 EP0988371A1 (en) 2000-03-29
EP0988371A4 true EP0988371A4 (en) 2002-11-04

Family

ID=21981206

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980926471 Withdrawn EP0988371A4 (en) 1997-06-11 1998-06-10 Human tumor necrosis factor receptor tr9

Country Status (5)

Country Link
EP (1) EP0988371A4 (en)
JP (1) JP2002503963A (en)
AU (1) AU7830398A (en)
CA (1) CA2295991A1 (en)
WO (1) WO1998056892A1 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US6713061B1 (en) 1996-03-12 2004-03-30 Human Genome Sciences, Inc. Death domain containing receptors
WO1997033904A1 (en) 1996-03-12 1997-09-18 Human Genome Sciences, Inc. Death domain containing receptors
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
EP1007659B1 (en) 1997-01-14 2007-06-27 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6 alpha & 6 beta
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
US6358508B1 (en) 1997-06-11 2002-03-19 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR9
US6949358B1 (en) 1997-06-11 2005-09-27 Human Genome Sciences, Inc. Human tumor necrosis factor receptor TR9
US6194151B1 (en) 1997-09-26 2001-02-27 Millenium Pharmaceuticals, Inc. Molecules of the TNF receptor superfamily and uses therefor
GB9812607D0 (en) * 1998-06-12 1998-08-12 Zeneca Ltd Protein
US6916907B1 (en) 1998-10-23 2005-07-12 Curagen Corporation Nucleic acids encoding osteoprotegern-like proteins and methods of using same
WO2000034294A2 (en) * 1998-12-11 2000-06-15 Bristol-Myers Squibb Company Tumor necrosis factor receptor homologue-1 ('trh1')
EP2357192A1 (en) 1999-02-26 2011-08-17 Human Genome Sciences, Inc. Human endokine alpha and methods of use
EP1171579A4 (en) * 1999-03-24 2002-07-31 Human Genome Sciences Inc Human tumor necrosis factor receptor tr9
NZ521540A (en) 2000-04-11 2004-09-24 Genentech Inc Multivalent antibodies and uses therefor
EP2267026A1 (en) 2000-04-12 2010-12-29 Human Genome Sciences, Inc. Albumin fusion proteins
EP1282441A2 (en) * 2000-05-10 2003-02-12 Eli Lilly And Company Treating t-cell mediated diseases by modulating dr6 activity
EP1294949A4 (en) 2000-06-15 2004-08-25 Human Genome Sciences Inc Human tumor necrosis factor delta and epsilon
AU6842701A (en) 2000-06-16 2002-01-14 Human Genome Sciences Inc Antibodies that immunospecifically bind to blys
JP4309758B2 (en) 2001-05-25 2009-08-05 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Antibodies that immunospecifically bind to TRAIL receptors
PT1463751E (en) 2001-12-21 2013-08-26 Human Genome Sciences Inc Albumin fusion proteins
JO3000B1 (en) 2004-10-20 2016-09-05 Genentech Inc Antibody Formulations.
AU2006344395B2 (en) 2005-10-13 2013-05-02 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive diseases
WO2010045002A2 (en) 2008-09-26 2010-04-22 Tocagen Inc. Gene therapy vectors and cytosine deaminases
JP5773879B2 (en) 2008-11-25 2015-09-02 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Use of DR6 and p75 antagonists to promote survival of cells of the nervous system
EP2640744A4 (en) 2010-11-19 2014-05-28 Eisai R&D Man Co Ltd Neutralizing anti-ccl20 antibodies
WO2014066700A1 (en) 2012-10-25 2014-05-01 Tocagen Inc. Retroviral vector with mini-promoter cassette
WO2021110110A1 (en) 2019-12-03 2021-06-10 上海交通大学医学院 ANTIBODY FC REGION HAVING ENHANCED FCγRIIB AFFINITY

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011790A1 (en) * 1997-09-04 1999-03-11 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-6
WO2000056862A1 (en) * 1999-03-24 2000-09-28 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9
US6358508B1 (en) * 1997-06-11 2002-03-19 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR9

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
EP0394827A1 (en) 1989-04-26 1990-10-31 F. Hoffmann-La Roche Ag Chimaeric CD4-immunoglobulin polypeptides
US5462856A (en) 1990-07-19 1995-10-31 Bunsen Rush Laboratories, Inc. Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins
WO1994009137A1 (en) 1992-10-15 1994-04-28 Genentech, Inc. Antibodies against type 2 tumor necrosis factor receptor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358508B1 (en) * 1997-06-11 2002-03-19 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR9
WO1999011790A1 (en) * 1997-09-04 1999-03-11 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-6
WO2000056862A1 (en) * 1999-03-24 2000-09-28 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 18 February 1996 (1996-02-18), XP002215173, retrieved from EMBL Database accession no. N49208 *
DATABASE EMBL [online] 18 January 1997 (1997-01-18), XP002215175, retrieved from EMBL Database accession no. AA156356 *
DATABASE EMBL [online] 19 January 1997 (1997-01-19), XP002215169, retrieved from EMBL Database accession no. AA155873 *
DATABASE EMBL [online] 19 January 1997 (1997-01-19), XP002215172, retrieved from EMBL Database accession no. AA186423 *
DATABASE EMBL [online] 22 April 1998 (1998-04-22), XP002215170, retrieved from EMBL Database accession no. AA918818 *
DATABASE EMBL [online] 27 August 1995 (1995-08-27), XP002215174, retrieved from EMBL Database accession no. D59902 *
DATABASE EMBL [online] 5 August 1995 (1995-08-05), XP002215176, retrieved from EMBL Database accession no. H41873 *
DATABASE EMBL [online] 5 October 1996 (1996-10-05), XP002215171, retrieved from EMBL Database accession no. AA072902 *
See also references of WO9856892A1 *

Also Published As

Publication number Publication date
CA2295991A1 (en) 1998-12-17
EP0988371A1 (en) 2000-03-29
AU7830398A (en) 1998-12-30
JP2002503963A (en) 2002-02-05
WO1998056892A1 (en) 1998-12-17

Similar Documents

Publication Publication Date Title
EP0988371A4 (en) Human tumor necrosis factor receptor tr9
EP0822984A4 (en) Human tumor necrosis factor receptors
EP1007562A4 (en) TUMOR NECROSIS FACTOR RECEPTOR RELATED PROTEINS TANGO-63d AND TANGO-63e
AU9013998A (en) Tumor necrosis factor receptor ztnfr-5
GB2323531B (en) Therapeutic formulations
ZA952587B (en) Human tumor necrosis factor receptor
AU7705198A (en) Human tumor necrosis factor receptor tr10
ZA982368B (en) New therapeutic combinations
EP0961782A4 (en) Human tumor necrosis factor receptor-like 2
EP1009431A4 (en) Human tumor necrosis factor receptor-like 2 (tr2) antibodies
AU9130598A (en) Tumor necrosis factor receptor ztnfr-6
EP1191940A4 (en) Tumor necrosis factor receptor 5
EP1171579A4 (en) Human tumor necrosis factor receptor tr9
GB9723999D0 (en) Therapeutic use
GB9703633D0 (en) Cancer therapy
GB9726701D0 (en) Therapeutic use
EP1210370A4 (en) Human tumor necrosis factor receptor tr16
ZA954143B (en) Human tumor necrosis factor receptors.
GB9726702D0 (en) Therapeutic use
AU2159995A (en) Human tumor necrosis factor receptor
GB9721173D0 (en) Therapeutic use
GB9721190D0 (en) Therapeutic use
GB9726700D0 (en) Therapeutic use
GB9721193D0 (en) Therapeutic use
GB9721194D0 (en) Therapeutic use

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000111

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched
AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20021104

17Q First examination report despatched

Effective date: 20040701

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 14/715 20060101ALI20100412BHEP

Ipc: C07K 14/705 20060101ALI20100412BHEP

Ipc: C07K 14/47 20060101AFI20100412BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: HUMAN GENOME SCIENCES, INC.

18D Application deemed to be withdrawn

Effective date: 20101110