EP0961782A4 - Human tumor necrosis factor receptor-like 2 - Google Patents

Human tumor necrosis factor receptor-like 2

Info

Publication number
EP0961782A4
EP0961782A4 EP96942776A EP96942776A EP0961782A4 EP 0961782 A4 EP0961782 A4 EP 0961782A4 EP 96942776 A EP96942776 A EP 96942776A EP 96942776 A EP96942776 A EP 96942776A EP 0961782 A4 EP0961782 A4 EP 0961782A4
Authority
EP
European Patent Office
Prior art keywords
necrosis factor
tumor necrosis
factor receptor
human tumor
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96942776A
Other languages
German (de)
French (fr)
Other versions
EP0961782A1 (en
Inventor
Jian Ni
Craig A Rosen
Reiner L Gentz
Sally Doreen Patricia Lyn
Mark Robert Hurle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
SmithKline Beecham Corp
Original Assignee
Human Genome Sciences Inc
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, SmithKline Beecham Corp filed Critical Human Genome Sciences Inc
Publication of EP0961782A1 publication Critical patent/EP0961782A1/en
Publication of EP0961782A4 publication Critical patent/EP0961782A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP96942776A 1996-10-30 1996-10-30 Human tumor necrosis factor receptor-like 2 Withdrawn EP0961782A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/018540 WO1998018824A1 (en) 1996-10-30 1996-10-30 Human tumor necrosis factor receptor-like 2

Publications (2)

Publication Number Publication Date
EP0961782A1 EP0961782A1 (en) 1999-12-08
EP0961782A4 true EP0961782A4 (en) 2003-07-16

Family

ID=22256163

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96942776A Withdrawn EP0961782A4 (en) 1996-10-30 1996-10-30 Human tumor necrosis factor receptor-like 2

Country Status (4)

Country Link
EP (1) EP0961782A4 (en)
JP (1) JP2001502912A (en)
CA (1) CA2270913C (en)
WO (1) WO1998018824A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7427492B1 (en) 1995-06-05 2008-09-23 Human Genome Sciences, Inc. Polynucleotides encoding human tumor necrosis factor receptor-like2
US6291207B1 (en) 1995-07-28 2001-09-18 Northwestern University Herpes virus entry receptor protein
US6140467A (en) * 1997-07-07 2000-10-31 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6998108B1 (en) 1997-07-07 2006-02-14 La Jolla Institute For Allergy And Immunology Antibodies to p30 polypeptides and methods making and using same
US7118742B2 (en) 1997-07-07 2006-10-10 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6346388B1 (en) 1997-08-13 2002-02-12 Smithkline Beecham Corporation Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2
US6287808B1 (en) 1998-09-03 2001-09-11 Millennium Pharmaceuticals, Inc. Molecules of the herpesvirus-entry-mediator-related protein family and uses thereof
WO2000014230A1 (en) * 1998-09-03 2000-03-16 Millennium Pharmaceuticals, Inc. Novel molecules of the herpes virus-entry-mediator-related protein family and uses thereof
TR200504220T2 (en) 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Active lymphotoxin-beta receptor immunoglobulin chime A method for high level expression and purification of purified protein proteins and a method for purification of active lymphotoxin-beta receptor immunoglobulin chimeric proteins.
CA2399388A1 (en) 2000-02-11 2001-08-16 Michael J. Lenardo Identification of a domain in the tumor necrosis factor receptor family that mediates pre-ligand receptor assembly and function
WO2001079496A2 (en) * 2000-03-13 2001-10-25 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
DE60143231D1 (en) * 2000-04-12 2010-11-18 Jolla Inst Allergy Immunolog Ligand of the cell entry-mediating protein of herpes simplex and methods for its uses
US20040235173A1 (en) * 2000-07-03 2004-11-25 Gala Design, Inc. Production of host cells containing multiple integrating vectors by serial transduction

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0393438A2 (en) * 1989-04-21 1990-10-24 Synergen, Inc. TNF-receptor, TNF-binding protein and DNA coding therefor
EP0822984A1 (en) * 1995-04-27 1998-02-11 Human Genome Sciences, Inc. Human tumor necrosis factor receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
US5464938A (en) * 1990-04-09 1995-11-07 Immunex Corporation Isolated viral protein TNF antagonists

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0393438A2 (en) * 1989-04-21 1990-10-24 Synergen, Inc. TNF-receptor, TNF-binding protein and DNA coding therefor
EP0822984A1 (en) * 1995-04-27 1998-02-11 Human Genome Sciences, Inc. Human tumor necrosis factor receptors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MONTGOMERY R I ET AL: "NEW MEMBER OF THE TNF/INGF RECEPTOR FAMILY CAN MEDIATE HERPES SIMPLEX VIRUS 1 ENTRY INTO CELLS", EUROPEAN CYTOKINE NETWORK, JOHN LIBBEY EUROTEXT LTD., MONTROUGE, FR, vol. 7, no. 2, June 1996 (1996-06-01), pages 159, XP000941008, ISSN: 1148-5493 *
See also references of WO9818824A1 *
SMITH C A ET AL: "A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 248, 25 May 1990 (1990-05-25), pages 1019 - 1022-1023, XP002107350, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
WO1998018824A1 (en) 1998-05-07
CA2270913A1 (en) 1998-05-07
JP2001502912A (en) 2001-03-06
WO1998018824A9 (en) 1999-09-30
CA2270913C (en) 2011-05-24
EP0961782A1 (en) 1999-12-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19990531

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20030602

17Q First examination report despatched

Effective date: 20031028

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050728