EP0957912A4 - - Google Patents

Info

Publication number
EP0957912A4
EP0957912A4 EP97941379A EP97941379A EP0957912A4 EP 0957912 A4 EP0957912 A4 EP 0957912A4 EP 97941379 A EP97941379 A EP 97941379A EP 97941379 A EP97941379 A EP 97941379A EP 0957912 A4 EP0957912 A4 EP 0957912A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97941379A
Other versions
EP0957912A1 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1996/013855 external-priority patent/WO1997007798A1/en
Application filed filed Critical
Publication of EP0957912A1 publication Critical patent/EP0957912A1/en
Publication of EP0957912A4 publication Critical patent/EP0957912A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP97941379A 1996-08-30 1997-08-29 Pharmaceutical compounds Withdrawn EP0957912A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/US1996/013855 WO1997007798A1 (en) 1995-08-30 1996-08-30 Pharmaceutical compounds
WOPCT/US96/13855 1996-08-30
US3898997P 1997-02-26 1997-02-26
US38989P 1997-02-26
US3952997P 1997-03-03 1997-03-03
US39529P 1997-03-03
PCT/US1997/015245 WO1998008506A1 (en) 1996-08-30 1997-08-29 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
EP0957912A1 EP0957912A1 (en) 1999-11-24
EP0957912A4 true EP0957912A4 (zh) 1999-12-22

Family

ID=27365489

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97941379A Withdrawn EP0957912A1 (en) 1996-08-30 1997-08-29 Pharmaceutical compounds

Country Status (5)

Country Link
EP (1) EP0957912A1 (zh)
JP (1) JP2001502297A (zh)
AU (1) AU4330097A (zh)
CA (1) CA2263420A1 (zh)
WO (1) WO1998008506A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0869786B1 (en) * 1995-12-22 2003-03-05 Eli Lilly And Company Pharmaceutical compounds
JP2001500484A (ja) * 1996-08-30 2001-01-16 イーライ・リリー・アンド・カンパニー 医薬化合物の製造法
EP0929556A4 (en) * 1996-09-06 2001-04-18 Lilly Co Eli PROCESS AND NEW INTERMEDIATES
WO1998009988A1 (en) * 1996-09-06 1998-03-12 Eli Lilly And Company Process to prepare pharmaceutical compounds
JP2001513775A (ja) * 1997-02-26 2001-09-04 イーライ・リリー・アンド・カンパニー トリペプチドおよびテトラペプチド医薬化合物
EA002547B1 (ru) * 1997-02-26 2002-06-27 Эли Лилли Энд Компани Способ селективного эпоксидирования для получения лекарственных соединений
US6180679B1 (en) * 1998-04-07 2001-01-30 Eli Lilly And Company Method for treating fungal infections
US6103913A (en) * 1998-10-16 2000-08-15 Eli Lilly And Company Process for preparing enollactone derivatives
US6376230B1 (en) 1998-10-16 2002-04-23 Eli Lilly And Company Stereoselective process for producing intermediates of cryptophycins
US7303749B1 (en) 1999-10-01 2007-12-04 Immunogen Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
JP2006516275A (ja) * 2003-01-22 2006-06-29 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー シクロプロピルβ−アミノ酸誘導体
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007798A1 (en) * 1995-08-30 1997-03-06 Eli Lilly And Company Pharmaceutical compounds
EP0792875A1 (en) * 1996-02-27 1997-09-03 Eli Lilly And Company Cryptophycin derivatives and their use as anti-microtubule agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69427706T2 (de) * 1993-12-21 2001-10-25 Univ Hawaii Honolulu Cryptophycine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007798A1 (en) * 1995-08-30 1997-03-06 Eli Lilly And Company Pharmaceutical compounds
WO1997008334A1 (en) * 1995-08-30 1997-03-06 University Of Hawaii Cryptophycins from aberrant biosynthesis
EP0792875A1 (en) * 1996-02-27 1997-09-03 Eli Lilly And Company Cryptophycin derivatives and their use as anti-microtubule agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9808506A1 *

Also Published As

Publication number Publication date
JP2001502297A (ja) 2001-02-20
EP0957912A1 (en) 1999-11-24
WO1998008506A1 (en) 1998-03-05
CA2263420A1 (en) 1998-03-05
AU4330097A (en) 1998-03-19

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19990224

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19991104

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 6A 61K 31/395 A, 6C 07D 273/08 B, 6C 07D 413/06 B

17Q First examination report despatched

Effective date: 20010730

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20020212