Classifications

• • C—CHEMISTRY; METALLURGY
  • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
  • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
  • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
  • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
• • C—CHEMISTRY; METALLURGY
  • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
  • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
  • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
  • C11D1/66—Non-ionic compounds
  • C11D1/835—Mixtures of non-ionic with cationic compounds
  • C11D1/8355—Mixtures of non-ionic with cationic compounds containing a combination of non-ionic compounds differently alcoxylised or with different alkylated chains
• • C—CHEMISTRY; METALLURGY
  • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
  • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
  • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
  • C11D1/008—Polymeric surface-active agents
• • C—CHEMISTRY; METALLURGY
  • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
  • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
  • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
  • C11D1/38—Cationic compounds
  • C11D1/62—Quaternary ammonium compounds
• • C—CHEMISTRY; METALLURGY
  • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
  • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
  • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
  • C11D1/66—Non-ionic compounds
  • C11D1/72—Ethers of polyoxyalkylene glycols
• • C—CHEMISTRY; METALLURGY
  • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
  • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
  • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
  • C11D1/66—Non-ionic compounds
  • C11D1/722—Ethers of polyoxyalkylene glycols having mixed oxyalkylene groups; Polyalkoxylated fatty alcohols or polyalkoxylated alkylaryl alcohols with mixed oxyalkylele groups

Definitions

• the present invention relates to improvements in cleaning compositions. More particularly the present invention is directed to improved cleaning compositions which find particular use in hard surface cleaning and disinfecting applications.
• compositions of the invention are aqueous disinfecting and cleaning compositions and concentrates thereof which are effective cleaning compositions and are efficacious as disinfecting compositions against gram positive and gram negative bacteria, have relatively low volatile organic content ("VOC") and are mild to the user of the compositions. That these results are concurrently achieved with a composition which includes a quaternary ammonium compound as its primary germicidal active agent is surprising, and indicates a synergistic effect not apparent from the prior art.
• VOC volatile organic content
• an aqueous disinfecting and cleaning composition in a concentrated form which comprises, but desirably consists essentially of: a disinfecting effective amount of a quaternary ammonium compound having germicidal properties, desirably present in an amount of from about 0.001 -
• a nonionic surfactant compound which is based on a polymeric alkylene oxide block copolymer
• a builder desirably present in an amount of about 0.1 - 0.5%wt; optionally, minor amounts of up to about 5%wt. of one or more conventional additives particularly coloring agents, fragrances and fragrance solubilizers, viscosity modifying agents such as thickeners, pH adjusting agents and pH buffers including organic and inorganic salts; and, water to form 100%wt. of the concentrate form of the inventive compositions.
• one or more conventional additives particularly coloring agents, fragrances and fragrance solubilizers, viscosity modifying agents such as thickeners, pH adjusting agents and pH buffers including organic and inorganic salts.
• a process for cleaning and/or disinfecting surfaces in need of such treatment which includes contacting a surface with a concentrate composition or aqueous dilution of a concentrate composition as taught herein.
• the concentrated disinfecting and cleaning compositions provided herein provide good cleaning, effective sanitization of surfaces particularly hard surfaces, and low irritancy to the consumer.
• the compositions of the invention include a disinfecting effective amount of a quaternary ammonium compound having germicidal properties.
• Particularly useful quaternary ammonium compounds and salts thereof include quaternary ammonium germicides which may be characterized by the general structural formula:
• the remaining radicals on the nitrogen atoms other than the hydrophobic radicals are substituents of a hydrocarbon structure usually containing a total of no more than 12 carbon atoms.
• the radicals R,, R 2 , R and R 4 may be straight chained or may be branched, but are preferably straight chained, and may include one or more amide or ester linkages.
• the radical X may be any salt-forming anionic radical.
• Exemplary quaternary ammonium salts within the above description include the alkyl ammonium halides such as cetyl trimethyl ammonium bromide, alkyl aryl ammonium halides such as octadecyl dimethyl benzyl ammonium bromide, N-alkyl pyridinium halides such as N-cetyl pyridinium bromide, and the like.
• quaternary ammonium salts include those in which the molecule contains either amide or ester linkages such as octyl phenoxy ethoxy ethyl dimethyl benzyl ammonium chloride, N-(laurylcocoaminoformylmethyl)-pyridinium chloride, and the like.
• Preferred quaternary ammonium compounds which act as germicides and which are be found useful in the practice of the present invention include those which have the structural formula:
• R, and R 3 are the same or different C 8 -C,, alkyl, or R 2 is C l2.16 alkyl, C 8 . l8 alkylethoxy, C 8.18 alkylphenolethoxy and R, is benzyl, and X is a halide, for example chloride, bromide or iodide, or X may be methosulfate.
• the alkyl groups recited in R 2 and R 3 may be straight chained or branched, but are preferably substantially linear.
• these quaternary ammonium compounds may be used singly or in mixtures of two or more. These quaternary ammonium compounds are desirably present in the concentrate compositions in an amount of from about 0.001 - 5% wt., are desirably present in an amount of from 0.1 - 3%wt. and most desirably are present in an amount of from 0.5 - 3%wt. When diluted in a larger volume of water to form a cleaning and disinfecting composition, the quaternary ammonium compounds should be present in sufficient amount such that they are in a concentration of at least about 150 parts per million (p.p.m.), more desirably at least about 175 p.p.m.
• a further constituent of invention is a nonionic surfactant compound which is based on a polymeric alkylene oxide block copolymer.
• Polymeric alkylene oxide block copolymers include nonionic surfactants in which the major portion of the molecule is made up of block polymeric C 2 -C alkylene oxides.
• Such nonionic surfactants while preferably built up from an alkylene oxide chain starting group, and can have as a starting nucleus almost any active hydrogen containing group including, without limitation, amides, phenols, thiols and secondary alcohols.
• One group of such useful nonionic surfactants containing the characteristic alkylene oxide blocks are those which may be generally represented by the formula (A):
• PO represents propylene oxide
• y equals at least 15
• (EO) +2 20 to 50% of the total weight of said compounds, and, the total molecular weight is preferably in the range of about 2000 to 15,000.
• Another group of nonionic surfactants appropriate for use in the new compositions can be represented by the formula (B):
• nonionic surfactants which in general are encompassed by Formula B include butoxy derivatives of propylene oxide/ethylene oxide block polymers having molecular weights within the range of about 2000-5000.
• nonionic surfactants containing polymeric butoxy (BO) groups can be represented by formula (C) as follows:
• nonionic block copolymer surfactants which also include polymeric butoxy groups, are those which may be represented by the following formula (D):
• nonionic block copolymer surfactants include ethoxylated derivatives of propoxylated ethylene diamine, which may be represented by the following formula:
• (EO) represents ethoxy
• (PO) represents propoxy
• the amount of (PO) x is such as to provide a molecular weight prior to ethoxylation of about 300 to 7500
• the amount of (EO) v is such as to provide about 20% to 90% of the total weight of said compound.
• HLB values are also available in a wide range of HLB values, and those having HLB values in the range of 1.0 - 23.0 may be used, although those with intermediate HLB values such as from about 12.0 - 18.0 are found to be particularly advantageous. These materials are presently commercially available from BASF AG (Ludwigshafen, Germany).
• Nonionic block copolymers based on a polymeric ethoxy/propoxy units include those presently commercially available in the Poly-Tergent® E, and Poly-Tergent® P from Olin Chemicals Corp., (Stamford CT).
• nonionic surfactants based on polymeric alkylene oxide block copolymers may be used singly or in mixtures of two or more such compounds.
• These nonionic surfactant compounds are desirably present in the concentrate compositions in an amount of from about 0.01 - 10%wt., desirably in an amount of 0.1 - 4%wt. and most desirably in an amount of 1 - 4%wt.
• ethylene oxide for example, lauryl or myristyl alcohol condensed with about 16 moles of ethylene oxide, tridecanol condensed with about 6 to moles of ethylene oxide, myristyl alcohol condensed with about 10 moles of ethylene oxide per mole of myristyl alcohol, the condensation product of ethylene oxide with a distillation or separation fraction of coconut fatty alcohol containing a mixture of fatty alcohols with alkyl chains varying from 10 to about 14 carbon atoms in length and wherein the condensate contains either about 6 moles of ethylene oxide per mole of total alcohol or about 9 moles of ethylene oxide per mole of alcohol and tallow alcohol ethoxylates containing 6 ethylene oxide to 11 ethylene oxide per mole of alcohol.
• nonionic surfactants include certain alkoxylated linear aliphatic alcohol surfactants which are believed to be the condensation products of a C 8 -C l0 hydrophilic moiety with alkylene oxides, especially polyethylene oxide and or polypropylene oxide moieties.
• alkoxylated linear alcohol surfactants are presently commercially available under the tradename PolyTergent® (Olin Chemical Co., Stamford CT). Of these particularly useful are those which are marketed as PolyTergent® SL-22, PolyTergent® SL-42, PolyTergent® SL-62 and PolyTergent®
• PolyTergent® SL-29 of which PolyTergent® SL-62 is particularly advantageous.
• PolyTergent® SL- 62 is described as being a moderately foaming, biodegradable alkoxylated linear alcohol surfactant having on average 8 moles of oxyethylene groups per molecule.
• These alkoxylated linear alcohol surfactants provide good detersive action in the removal of many types of fats and greases such as are frequently found in soils on hard surfaces, as well as providing a further solubilizing effects and may be included in the concentrate compositions according to the present invention with advantage.
• the preferred alkoxylated linear alcohol surfactants also exhibit low levels of ocular irritation in the concentrate compositions.
• Further useful nonionic surfactants include alkoxylated, and particularly ethoxylated octyl and nonyl phenols according to the following general structural formulas:
• Suitable non-ionic ethoxylated octyl and nonyl phenols include those having from about 7 to about 13 ethoxy units. Such compounds are commercially available under the trade name Triton® X (Union Carbide, Danbury CT).
• alkoxylated alkyl phenols useful as a nonionic surfactant also include certain compositions presently commercially available from the Rh ⁇ ne-
• Igepal® Poulenc Co., (Cranbury, NJ) under the general trade name Igepal®, which are described to be octyl and nonyl phenols. These specifically include Igepal® CO730 which is described as an ethoxylated nonyl phenol having an average of 15 ethoxy groups per molecule.
• a further useful class of nonionic surfactants are those based on alkylpolyglycosides.
• Suitable alkyl mono and polyglycosides are prepared generally by reacting a monosaccharide, or a compound hydrolyzable to a monosaccharide with an alcohol such as a fatty alcohol in an acid medium.
• Z is selected 0 2 M'
• R 2 is (CH 2 )C0 2 M' or
• M' is H * or an organic or inorganic cation, such as, for example, an alkali metal, ammonium, monoethanolamine, or calcium
• R is generally the residue of a fatty alcohol having from about 8 to 30 and preferably 8 to 18 carbon atoms
• alkylglycosides as desc ⁇ bed above include, for example, APGTM 325 CS
• GLYCOSIDE which is desc ⁇ bed as being a 50% C r C ⁇ alkyl polyglycoside, also commonly referred to as D-glucopyranoside, (commercially available from Henkel Corp, Ambler PA) and GLUCOPONTM 625 CS which is desc ⁇ bed as being a 50% C
• nonionic surfactant compounds desc ⁇ bed above may be used singly or in mixtures They comp ⁇ se 0 01 - 10%wt of the concentrate compositions, desirably comp ⁇ se 0 1 - 7%wt and most desirably comp ⁇ se about 2 5-6%wt and especially about 5%wt of the concentrate compositions taught herein
• inventive compositions optionally but desirably include a builder Such a builder constituent may be present in an amount of from 0 - 3%wt based on the total weight of the concentrate compositions taught herein
• Exemplary builders include alkali metal carbonates, phosphates, polyphosphates and silicates, including sodium carbonate and sodium sesquicarbonate
• Further exemplary builders include organic alkaline sequestrant builder salts such as alkali metal polycarboxylates including water-soluble citrates such as sodium and potassium citrate, sodium and potassium tartarate, sodium and potassium ethylenediaminetetraacetate, sodium and potassium N-(2-hydroxyethyl)- ethylene diamine triacetates, sodium and potassium nitrilotriacetates, as well as sodium and potassium tartrate mono- and di-succinates.
• gluconate or glucoheptonate salts particularly sodium gluconate and sodium glucoheptonate.
• organic builder salts are di-, tri- and tetrasodium salts of ethylenediaminetetraacetic acid, especially tetrasodium salts thereof.
• these organic builder salts may be used individually, as a combination of two or more organic builder salts, as well as in conjunction with one or more detergency builders, including those indicated above.
• An optional but particularly desirable further constituent is a cationic polymeric polyquatemary ammonium salt, especially a halogen salt such as a chloride salt.
• a cationic polymeric polyquatemary ammonium salt especially a halogen salt such as a chloride salt.
• Such a material is one which includes at least one repeating monomer unit wherein such monomer includes as part of its structure a quaternary ammonium.
• a particularly useful class of such materials are those sold under the trade designation "Mirapol®" and are available from Rh ⁇ ne-Poulenc Surfactant & Specialty Chemicals Co. (Cranbury, NJ). These materials are highly cationic in nature, and are believed to be in accordance with the following general structure:
• n is an integer or 2 or greater, and is desirably in the range of 2 - 12, more desirably is about 6.
• Mirapol® A- 15 from from Rh ⁇ ne-Poulenc, identified above.
• compositions according to the invention are known, and are commercially available from a number of sources
• the compositions according to the invention are useful in the disinfecting and/or cleaning of surfaces, especially hard surfaces in need of such treatment These in particular include surfaces wherein the presence of gram positive and/or gram negative bacte ⁇ a are suspected
• cleaning and/or disinfecting of such surfaces compnses the step of applying a stain releasing and a disinfecting effective amount of a composition as taught herein to such a stained surface Afterwards, the compositions are optionally but desirably wiped, scrubbed or otherwise physically contacted with the hard surface, and further optionally, may be subsequently ⁇ nsed from such a cleaned and disinfected hard surface
• Such a hard surface cleaning and disinfecting composition according to the invention is may be provided as a ready to use product which may be directly applied to a hard surface, but is desirably provided in a concentrated form intended to be diluted in water to form a cleaning composition therefrom
• compositions according to the invention can also be provided as a ready to use product in a manually operated spray dispensing container
• the compositions according to the invention may be formulated so that it may be useful in conjunction with a "aerosol" type product wherein it is discharged from a pressu ⁇ zed aerosol container
• cleaning compositions are most beneficial for use in their form, I e , their form as described above, they may also be diluted to form a cleaning composition therefrom Such cleaning compositions may be easily prepared by diluting measured amounts of the compositions in further amounts of water by the consumer or other end user in certain weight ratios of composition water, and optionally, agitating the same to ensure even distribution of the composition m the water
• the concentrate compositions according to the invention may be used without further dilution, but may also be used with a further aqueous dilution, i.e , in concentrate composition water concentrations of 1 0, to extremely dilute dilutions such as 1 1000
• a dilution is preferably a weight or volume ratio proportion of from 1 10 - 1 64, and most desirably is about 1 64
• the actual dilution selected is in part determinable by the degree and amount of dirt and g ⁇ me to be removed from a surface(s), the amount of mechanical force imparte
• Exemplary optional conventional additives include but are not limited to pH adjusting agents and pH buffers including organic and inorganic salts, non-aqueous solvents, perfumes, perfume earners, optical b ⁇ ghteners, colo ⁇ ng agents such as dyes and pigments, opacifying agents, hydrotropes, antifoaming agents, viscosity modifying agents such as thickeners, enzymes, anti-spotting agents, anti-oxidants, anti-corrosion agents as well as others not specifically elucidated here These should be present m minor amounts, preferably in total comp ⁇ se less than about 5% by weight of the compositions, and desirably less than about 3%wt
• weight percents of any constituent are to be understood as the weight percent of the active portion of the referenced constituent, unless otherwise indicated
• Example Formulations Preparation of Example Formulations Exemplary formulations illustrating certain preferred embodiments of the inventive compositions and described in more detail in Table 1 below were formulated generally in accordance with the following protocol
• a measured amount of water was provided after which the constituents were added in no specific or uniform sequence, which indicated that the order of addition of the constituents was not critical. All of the constituents were supplied at room temperature, and any remaining amount of water was added thereafter. Certain of the nonionic surfactants were gelled at room temperature and were first preheated to render them pourable liquids prior to addition and mixing. Mixing of the constituents was achieved by the use of a mechanical stirrer with a small diameter propeller at the end of its rotating shaft. Mixing, which generally lasted from 5 minutes to 120 minutes was maintained until the particular exemplary formulation appeared to be homogeneous. The exemplary compositions were readily pourable, and retained well mixed characteristics (i.e., stable mixtures) upon standing for extend periods, even in excess of 120 days.
• compositions of the example formulations are listed on Table 1, below where are described the weights of the actives provided in the named constituent is indicated.
• Salmonella choleraesuis (gram negative type pathogenic bacteria) (ATCC 10708), and Pseudomonas aeruginosa (ATCC 15442).
• the testing was performed in accordance with the protocols outlined in "Use-Dilution Method", Protocols 955.14, 955.15 and 964.02 described in Chapter 6 of "Official Methods of Analysis", 16'" Edition, of the Association of Official Analytical Chemists; "Germicidal and Detergent Sanitizing Action of Disinfectants", 960.09 described in Chapter 6 of "Official Methods of Analysis", 15"' Edition, of the Association of Official Analytical Chemists; or American Society for Testing and Materials (ASTM) E 1054-91 the contents of which are herein incorporated by reference. This test is also commonly referred to as the "AOAC Use-Dilution Test Method".
• the results of the AOAC Use-Dilution Test Method indicates the number of test substrates wherein the tested organism remains viable after contact for 10 minutes with at test disinfecting composition / total number of tested substrates (cylinders) evaluated in accordance with the AOAC Use-Dilution Test.
• a result of "0/60” indicates that of 60 test substrates bearing the test organism and contacted for 10 minutes in a test disinfecting composition, 0 test substrates had viable (live) test organisms at the conclusion of the test.
• Such a result is excellent, illustrating the excellent disinfecting efficacy of the tested composition.
• Results for lesser amount of test substrates such as for 10, 20, 30 or 40 test substrates provide useful screening results, although insufficient to satisfy the requirement of 60 test substrates as dictated by the AOAC Use-Dilution Test. Results of the antimicrobial testing are indicated on Table 3, below. The reported results indicate the number of test cylinders with live test organisms/number of test cylinders tested for each example formulation and organism tested.
• Formulation Corneal opacity in test subjects / number of days
• Lt reflectance average after scrubbing solid tile
• Ls reflectance average before cleaning soiled tile
• the measurement of the cleaning effectiveness of the test samples involved the ability of the cleaning composition to remove the test soil from the test substrate. This was expressed by Cleaning Efficiency; as numerical values for a Cleaning Efficiency increase, higher cleaning effectiveness is achieved for the cleaning composition tested. As the results show, the inventive composition showed excellent cleaning characteristics which favorably compare to the commercially available products.

Applications Claiming Priority (3)

Publications (1)

Family

ID=10804057

Family Applications (1)

Country Status (10)

Families Citing this family (10)

Family Cites Families (11)

• 1996
  • 1996-12-06 GB GB9625396A patent/GB2320030A/en not_active Withdrawn
• 1997
  • 1997-10-28 BR BR9713875-4A patent/BR9713875A/pt not_active IP Right Cessation
  • 1997-10-28 AU AU50829/98A patent/AU5082998A/en not_active Abandoned
  • 1997-10-28 WO PCT/US1997/018873 patent/WO1998024314A1/en not_active Application Discontinuation
  • 1997-10-28 CN CN 97180344 patent/CN1239864A/zh active Pending
  • 1997-10-28 CA CA002273484A patent/CA2273484A1/en not_active Abandoned
  • 1997-10-28 EP EP97913702A patent/EP0946091A1/de not_active Ceased
  • 1997-10-28 NZ NZ336091A patent/NZ336091A/xx unknown
  • 1997-12-04 AR ARP970105691 patent/AR010675A1/es unknown
  • 1997-12-04 ZA ZA9710895A patent/ZA9710895B/xx unknown

Non-Patent Citations (1)

Also Published As

Similar Documents

Legal Events