EP0939900A4 - DETECTION D'ANTICORPS DE RECEPTEUR GPIIb/IIIa DEPENDANT D'ANTAGONISTES - Google Patents
DETECTION D'ANTICORPS DE RECEPTEUR GPIIb/IIIa DEPENDANT D'ANTAGONISTESInfo
- Publication number
- EP0939900A4 EP0939900A4 EP97947553A EP97947553A EP0939900A4 EP 0939900 A4 EP0939900 A4 EP 0939900A4 EP 97947553 A EP97947553 A EP 97947553A EP 97947553 A EP97947553 A EP 97947553A EP 0939900 A4 EP0939900 A4 EP 0939900A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- gpiib
- antagonist
- dependent
- detection
- receptor antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3166196P | 1996-11-21 | 1996-11-21 | |
US31661P | 1996-11-21 | ||
US3546197P | 1997-01-14 | 1997-01-14 | |
US35461P | 1997-01-14 | ||
GB9702822 | 1997-02-12 | ||
GBGB9702822.9A GB9702822D0 (en) | 1997-02-12 | 1997-02-12 | Anticoagulant test |
GB9705856 | 1997-03-21 | ||
GBGB9705856.4A GB9705856D0 (en) | 1997-03-21 | 1997-03-21 | Anticoagulant test |
PCT/US1997/020954 WO1998022821A1 (fr) | 1996-11-21 | 1997-11-17 | DETECTION D'ANTICORPS DE RECEPTEUR GPIIa/IIIb DEPENDANT D'ANTAGONISTES |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0939900A1 EP0939900A1 (fr) | 1999-09-08 |
EP0939900A4 true EP0939900A4 (fr) | 2003-01-08 |
Family
ID=27451602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97947553A Withdrawn EP0939900A4 (fr) | 1996-11-21 | 1997-11-17 | DETECTION D'ANTICORPS DE RECEPTEUR GPIIb/IIIa DEPENDANT D'ANTAGONISTES |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0939900A4 (fr) |
JP (1) | JP2001504584A (fr) |
CA (1) | CA2271684A1 (fr) |
WO (1) | WO1998022821A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6623981B2 (en) | 1998-01-27 | 2003-09-23 | Bristol-Myers Squibb Company | Detection of patients at risk for developing integrin antagonist/agonist mediated disease states |
US20020132276A1 (en) * | 1999-01-26 | 2002-09-19 | Dicker Ira B. | FACS method for detecton of GPIIb/IIIa inhibitor dependent activators in plasma samples |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4717654A (en) * | 1984-06-19 | 1988-01-05 | Akzo N.V. | Process for solid phase platelet antibody assay |
FR2665769A1 (fr) * | 1990-08-09 | 1992-02-14 | Serbio | Determination des thrombopenies notamment induites par l'heparine au moyen du facteur plaquettaire 4. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
US5585243A (en) * | 1993-09-15 | 1996-12-17 | The Blood Center Of Southeastern Wisconsin, Inc. | Method of detecting cytopenia that is mediated by drug-dependent antibody binding to blood cells |
-
1997
- 1997-11-17 JP JP52378398A patent/JP2001504584A/ja active Pending
- 1997-11-17 WO PCT/US1997/020954 patent/WO1998022821A1/fr not_active Application Discontinuation
- 1997-11-17 EP EP97947553A patent/EP0939900A4/fr not_active Withdrawn
- 1997-11-17 CA CA002271684A patent/CA2271684A1/fr not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4717654A (en) * | 1984-06-19 | 1988-01-05 | Akzo N.V. | Process for solid phase platelet antibody assay |
FR2665769A1 (fr) * | 1990-08-09 | 1992-02-14 | Serbio | Determination des thrombopenies notamment induites par l'heparine au moyen du facteur plaquettaire 4. |
Non-Patent Citations (4)
Title |
---|
BEDNAR B ET AL: "DRUG-DEPENDENT ANTIBODIES AGAINST GPIIB/IIIA INDUCE THROMBOCYTOPENIA", CIRCULATION, AMERICAN HEART ASSOCIATION, DALLAS, TX, US, vol. 94, no. 8, SUPPL 1, 15 October 1996 (1996-10-15), pages 571, XP001029709, ISSN: 0009-7322 * |
CURTIS BRIAN R ET AL: "Antibodies in sulfonamide-induced immune thrombocytopenia recognize calcium-dependent epitopes on the glycoprotein IIb/IIIa complex.", BLOOD, vol. 84, no. 1, 1994, pages 176 - 183, XP001029348, ISSN: 0006-4971 * |
See also references of WO9822821A1 * |
VISENTIN G P ET AL: "DETECTION OF DRUG-DEPENDENT, PLATELET-REACTIVE ANTIBODIES BY ANTIGEN-CAPTURE ELISA AND FLOW CYTOMETRY", TRANSFUSION, AMERICAN ASSOCIATION OF BLOOD BANKS, BETHESDA, MD, US, vol. 30, no. 8, October 1990 (1990-10-01), pages 694 - 700, XP000983195, ISSN: 0041-1132 * |
Also Published As
Publication number | Publication date |
---|---|
EP0939900A1 (fr) | 1999-09-08 |
CA2271684A1 (fr) | 1998-05-28 |
WO1998022821A1 (fr) | 1998-05-28 |
JP2001504584A (ja) | 2001-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990621 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20021127 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7G 01N 33/53 A, 7G 01N 33/567 B, 7G 01N 33/566 B |
|
17Q | First examination report despatched |
Effective date: 20030704 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20031115 |