EP0917863A1 - Kanüle mit einem aus zwei Komponenten zusammengestellten Stopfen - Google Patents

Kanüle mit einem aus zwei Komponenten zusammengestellten Stopfen Download PDF

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Publication number
EP0917863A1
EP0917863A1 EP98402911A EP98402911A EP0917863A1 EP 0917863 A1 EP0917863 A1 EP 0917863A1 EP 98402911 A EP98402911 A EP 98402911A EP 98402911 A EP98402911 A EP 98402911A EP 0917863 A1 EP0917863 A1 EP 0917863A1
Authority
EP
European Patent Office
Prior art keywords
insert
straw according
membrane
straw
resins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP98402911A
Other languages
English (en)
French (fr)
Other versions
EP0917863B1 (de
Inventor
Jean-Gérard Saint-Ramon
Christian Beau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMV Technologies SA
Original Assignee
Instruments de Medecine Veterinaire SA IMV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instruments de Medecine Veterinaire SA IMV filed Critical Instruments de Medecine Veterinaire SA IMV
Publication of EP0917863A1 publication Critical patent/EP0917863A1/de
Application granted granted Critical
Publication of EP0917863B1 publication Critical patent/EP0917863B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
    • A61D19/022—Containers for animal semen, e.g. pouches or vials ; Methods or apparatus for treating or handling animal semen containers, e.g. filling or closing
    • A61D19/024—Tube-like containers, e.g. straws
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
    • Y10T428/1393—Multilayer [continuous layer]

Definitions

  • the present invention relates to a straw for the preservation of small quantities of substances, in particular biological substances, in particular of biological fluids.
  • An object of the invention is to provide a straw comprising a means shutter which, while being liquid tight and gas permeable, does not absorb no amount of liquid.
  • Another object of the present invention is to provide a glitter allowing absorption of liquid through the closure means in a reduced time.
  • the present invention meets these objects and provides a glitter for the storage of small quantities of substances, especially substances biological, consisting of a segment of tube fitted inside one of its ends of a sealing means, characterized in that said sealing means is a bipartite stopper consisting of a microporous and hydrophobic membrane and a insert pierced with a substantially coaxial orifice.
  • the insert is usually made of a material chosen from the materials elastomers, thermoplastic materials and elastomeric materials thermoplastics.
  • the insert has a shape substantially cylindrical exterior.
  • the insert is tubular, its orifice substantially coaxial which may for example be substantially cylindrical, conical or biconical.
  • the membrane surrounds the insert over part or all of its length.
  • the membrane is positioned substantially perpendicular to the longitudinal axis of the insert.
  • the insert is bipartite.
  • the insert can also be overmolded, glued or welded to the membrane.
  • the insert can be rounded at its ends.
  • the insert will advantageously include a sealing segment on its wall external.
  • the microporous membrane used in the present invention will have preferably a pore diameter of between approximately 0.001 and 10 ⁇ m, better still, the pore diameter of the membrane will be less than or equal to 0.2 ⁇ m.
  • the membrane is for example made of polymer material, for example, a material chosen from high density polyethylene (PE-HD), polyamides, nitrocellulose, polyesters, phenol-formaldehyde resins (PF resins), perfluoroalkoxy resins (PFA) and fluorocarbon resins.
  • PE-HD high density polyethylene
  • PF resins phenol-formaldehyde resins
  • PFA perfluoroalkoxy resins
  • fluorocarbon resins for example, a material chosen from high density polyethylene (PE-HD), polyamides, nitrocellulose, polyesters, phenol-formaldehyde resins (PF resins), perfluoroalkoxy resins (PFA) and fluorocarbon resins.
  • the polymeric material of the membrane will advantageously have a bubble point P greater than 6.10 5 Pa (6 bars) for 0.2 ⁇ m.
  • the plug of the straw of the present invention is non-absorbent vis-à-vis liquids. It allows only gases, especially air, to pass through and is liquids up to its intrusion pressure.
  • the other end of the glitter that is to say the one without the cap according to the invention, remains normally open for the introduction of the product to store, which is usually a liquid.
  • the open end is closed, for example by welding, in particular ultrasonic or thermal, or any other suitable technique known to those skilled in the art.
  • the cap of the invention has many advantages: it is non-toxic, sterilizable, it can be frozen or reheated without damage.
  • the cap of the invention is liquid tight. It neither absorbs the diluent nor sperm.
  • An advantage of the glitter cap according to the present invention is that it can quickly fill the straw.
  • the plug of the invention is also particularly advantageous because it allows only part of the liquid contained in the straw to be withdrawn while keeping the latter for later use. This was not possible with the tripartite plug of the prior art.
  • Another advantage of the invention is that this non-absorbent plug allows good adhesion to the parts of the glitter, thus preventing backwash well known when using the tripartite plug.
  • Another advantage of the invention is that the plug, by its porosity, ensures of course a filtration which makes it possible to work in a more or less sterile mode.
  • Another advantage of the invention is that it is also possible, with the same flake, reabsorb product.
  • Another advantage of the bipartite plug of the present invention is still ability to mark the glitter by coloring the insert. We thus obtain a "code color "without having to resort to colored glitter.
  • Figure 1 shows a straw 1 according to an embodiment of the invention fitted with the bipartite plug 2 consisting of the microporous and hydrophobic membrane 3 and an insert 4 pierced with a cylindrical orifice 5.
  • Figure 2 shows the glitter of Figure 1 in which the insert 4 has on its outer wall a sealing segment 6.
  • Figure 3 illustrates the embodiment of the invention according to which the orifice coaxial 5 is conical.
  • Figure 4 illustrates the embodiment of the invention according to which the orifice coaxial 5 is biconical.
  • FIG. 5 illustrates the embodiment of the invention according to which the insert 4 is bipartite.
  • Figure 6 illustrates the embodiment of the invention according to which the insert 4 is molded onto the membrane 3.
  • Figure 6bis illustrates the embodiment of the invention according to which the insert 4 is welded or glued to the membrane 3.
  • the membrane surrounds insert 4 over its entire length.
  • the membrane 3 surrounds the insert 4 over part of its length.
  • the membrane 3 is positioned substantially perpendicular to the longitudinal axis of the insert 4.
  • Figure 7 shows the straw 1 '"naked", the membrane 3 and the insert 4 according to the invention, separate.
  • Figure 8 shows the insert 4 on which the membrane 3 was threaded and the straw 1 ', before the introduction, in the direction of arrow F, of the insert 4 with the membrane 3 in the straw 1 '.
  • Figure 9 shows the straw 1 comprising the bipartite plug according to the present invention.

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Public Health (AREA)
  • Closures For Containers (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Packages (AREA)
  • Materials For Medical Uses (AREA)
EP98402911A 1997-11-24 1998-11-23 Kanüle mit einem aus zwei Komponenten zusammengestellten Stopfen Expired - Lifetime EP0917863B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714729A FR2771285B1 (fr) 1997-11-24 1997-11-24 Paillette avec bouchon bipartite
FR9714729 1997-11-24

Publications (2)

Publication Number Publication Date
EP0917863A1 true EP0917863A1 (de) 1999-05-26
EP0917863B1 EP0917863B1 (de) 2002-09-04

Family

ID=9513717

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98402911A Expired - Lifetime EP0917863B1 (de) 1997-11-24 1998-11-23 Kanüle mit einem aus zwei Komponenten zusammengestellten Stopfen

Country Status (6)

Country Link
US (1) US6472036B2 (de)
EP (1) EP0917863B1 (de)
AT (1) ATE223179T1 (de)
DE (2) DE29820912U1 (de)
DK (1) DK0917863T3 (de)
FR (1) FR2771285B1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0993930A1 (de) * 1998-10-15 2000-04-19 IMV Technologies Verfahren zum Herstellen eines Gegenstandes bestehend aus einem Träger und einer darauf geschweissten Membran, insbesondere eines Stopfens für ein Röhrchen und eine dadurch hergestellte Membran-Trägergruppe
FR3069755A1 (fr) * 2017-08-01 2019-02-08 Imv Technologies Paillette pour la conservation d'une dose predeterminee de substance a base liquide

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030087005A1 (en) * 1996-10-10 2003-05-08 Peter Baron Drink flavouring straw
AUPS270602A0 (en) 2002-05-31 2002-06-20 Baron, Peter Drink flavouring straw
FR2804416B1 (fr) 2000-01-31 2002-04-26 Imv Technologies Machine de convoyage et d'amenee en position de tubes, notamment de paillettes
GB0025315D0 (en) * 2000-10-16 2000-11-29 Capsule Technology Ltd Filtration container
FR2891166B1 (fr) * 2005-09-28 2007-11-23 Cryo Bio System Sa Enveloppe de conditionnement d'un volume predetermine de substance biologique destinee a etre plongee dans un agent cryogenique liquide
AR060029A1 (es) 2006-03-02 2008-05-21 Unistraw Patent Holdings Ltd Pajilla para beber adaptada para acondicionar progresivamente un ingrediente activo y metodo de fabricar dicha pajilla
FR2908038A1 (fr) * 2006-11-08 2008-05-09 Genes Diffusion Sa Sonde d'insemination artificielle pour animaux d'elevage
FR2932064B1 (fr) * 2008-06-06 2010-08-13 Imv Technologies Paillette pour la conservation d'une dose de substance a base liquide, notamment une substance biologique
FR3017793B1 (fr) 2014-02-21 2019-08-23 Imv Technologies Paillette pour la conservation d'une dose predeterminee de substance a base liquide, notamment une substance biologique
FR3017792B1 (fr) 2014-02-21 2019-08-23 Imv Technologies Paillette pour la conservation d'une dose predeterminee de substance a base liquide, notamment une substance biologique
FR3021522A1 (fr) 2014-05-28 2015-12-04 Imv Technologies Paillette pour la conservation d'une dose predeterminee de substance a base liquide, notamment de la semence animale diluee ; milieu de dilution pour donner une telle substance ; et systeme les comportant
FR3036954B1 (fr) 2015-06-03 2017-07-14 Imv Tech Paillette pour la conservation d'une dose predeterminee de substance a base liquide, ainsi que dispositif d'injection et procede la mettant en oeuvre
FR3074419B1 (fr) 2017-12-05 2019-12-27 Imv Technologies Paillette pour la conservation cryogenique d'une dose de substance a base liquide, ensemble la comportant et procede de vidage de cette paillette
US11116206B2 (en) 2018-10-01 2021-09-14 Cook Medical Technologies Llc Cryocontainer

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR995878A (fr) 1949-09-20 1951-12-10 Procédé pour la conservation à l'abri de l'air de petites quantités dosées de liquides et produit en résultant
FR1488345A (fr) * 1966-05-26 1967-07-13 Procédé et appareillage pour la récolte et le conditionnement de poses destinées à l'insémination artificielle des oiseaux et des petits mammifères
FR2651793A1 (fr) * 1989-09-14 1991-03-15 Cassou Robert Tubes ou paillettes pour la conservation cryogenique d'echantillons biologiques tels que virus, et procede de remplissage.
EP0622055A1 (de) * 1993-04-26 1994-11-02 Societe D'etudes, De Gestion, D'engineering Filtersammelvorrichtung einer viskosen Flüssigkeit

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558014A (en) * 1983-06-13 1985-12-10 Myron J. Block Assay apparatus and methods
US6117394A (en) * 1996-04-10 2000-09-12 Smith; James C. Membrane filtered pipette tip
US6145688A (en) * 1996-07-17 2000-11-14 Smith; James C. Closure device for containers
FR2771284B1 (fr) * 1997-11-24 2000-08-18 Instr Medecine Veterinaire Paillette avec insert adaptateur

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR995878A (fr) 1949-09-20 1951-12-10 Procédé pour la conservation à l'abri de l'air de petites quantités dosées de liquides et produit en résultant
FR1488345A (fr) * 1966-05-26 1967-07-13 Procédé et appareillage pour la récolte et le conditionnement de poses destinées à l'insémination artificielle des oiseaux et des petits mammifères
FR2651793A1 (fr) * 1989-09-14 1991-03-15 Cassou Robert Tubes ou paillettes pour la conservation cryogenique d'echantillons biologiques tels que virus, et procede de remplissage.
EP0622055A1 (de) * 1993-04-26 1994-11-02 Societe D'etudes, De Gestion, D'engineering Filtersammelvorrichtung einer viskosen Flüssigkeit

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0993930A1 (de) * 1998-10-15 2000-04-19 IMV Technologies Verfahren zum Herstellen eines Gegenstandes bestehend aus einem Träger und einer darauf geschweissten Membran, insbesondere eines Stopfens für ein Röhrchen und eine dadurch hergestellte Membran-Trägergruppe
FR2784572A1 (fr) * 1998-10-15 2000-04-21 Instr Medecine Veterinaire Procede de fabrication d'un element constitue d'un support et d'une membrane qui y est soudee, en particulier d'un bouchon de paillette, et ensemble membrane support obtenu par ce procede
US6416611B1 (en) 1998-10-15 2002-07-09 Imv Technologies Method of making a component consisting of a support and a membrane welded thereto, in particular a plug for a straw, and membrane-support
FR3069755A1 (fr) * 2017-08-01 2019-02-08 Imv Technologies Paillette pour la conservation d'une dose predeterminee de substance a base liquide

Also Published As

Publication number Publication date
DK0917863T3 (da) 2002-11-18
DE29820912U1 (de) 1999-02-11
EP0917863B1 (de) 2002-09-04
US20010014376A1 (en) 2001-08-16
US6472036B2 (en) 2002-10-29
DE69807627D1 (de) 2002-10-10
FR2771285A1 (fr) 1999-05-28
FR2771285B1 (fr) 2000-02-11
ATE223179T1 (de) 2002-09-15

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