EP0871455A4 - In-vitro wachstum von funktionalen langerhansinseln und deren in vivo verwendung - Google Patents
In-vitro wachstum von funktionalen langerhansinseln und deren in vivo verwendungInfo
- Publication number
- EP0871455A4 EP0871455A4 EP96936866A EP96936866A EP0871455A4 EP 0871455 A4 EP0871455 A4 EP 0871455A4 EP 96936866 A EP96936866 A EP 96936866A EP 96936866 A EP96936866 A EP 96936866A EP 0871455 A4 EP0871455 A4 EP 0871455A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- langerhans
- vitro growth
- vivo uses
- functional islets
- islets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0678—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US547746 | 1995-10-25 | ||
US08/547,746 US6001647A (en) | 1994-04-28 | 1995-10-25 | In vitro growth of functional islets of Langerhans and in vivo uses thereof |
PCT/US1996/016952 WO1997015310A1 (en) | 1995-10-25 | 1996-10-23 | In vitro growth of functional islets of langerhans and in vivo uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0871455A1 EP0871455A1 (de) | 1998-10-21 |
EP0871455A4 true EP0871455A4 (de) | 2003-05-14 |
Family
ID=24185961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96936866A Withdrawn EP0871455A4 (de) | 1995-10-25 | 1996-10-23 | In-vitro wachstum von funktionalen langerhansinseln und deren in vivo verwendung |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0871455A4 (de) |
JP (1) | JPH11514877A (de) |
AU (1) | AU739771B2 (de) |
CA (1) | CA2235509A1 (de) |
WO (1) | WO1997015310A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2359821A1 (en) * | 1999-02-04 | 2000-08-10 | Mcgill University | Platform for the differentiation of cells |
GB9914890D0 (en) * | 1999-06-25 | 1999-08-25 | Univ Buckingham | Methods and compositions relating to pancreatic islet and -cell dysfunction |
EP1224259A4 (de) * | 1999-09-27 | 2005-04-27 | Univ Florida | Rückbildung von insulinabhängigem diabetes durch inselbildende stammzellen, inselvorläuferzellen und inselähnliche strukturen |
WO2001032839A2 (en) * | 1999-10-29 | 2001-05-10 | Mcgill University | Medium for preparing dedifferentiated cells |
US20030082155A1 (en) | 1999-12-06 | 2003-05-01 | Habener Joel F. | Stem cells of the islets of langerhans and their use in treating diabetes mellitus |
US6866843B2 (en) | 1999-12-06 | 2005-03-15 | Viacell, Inc. | Method of transplanting in a mammal and treating diabetes mellitus by administering a pseudo-islet like aggregate differentiated from a nestin-positive pancreatic stem cell |
AU778155B2 (en) * | 1999-12-13 | 2004-11-18 | Scripps Research Institute, The | Markers for identification and isolation of pancreatic islet alpha and beta cell progenitors |
US6610535B1 (en) * | 2000-02-10 | 2003-08-26 | Es Cell International Pte Ltd. | Progenitor cells and methods and uses related thereto |
US6436704B1 (en) * | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
AU2001273108A1 (en) * | 2000-06-30 | 2002-01-14 | Amcyte, Inc. | Culturing pancreatic stem cells having a specified, intermediate stage of development |
US7202080B2 (en) | 2001-03-29 | 2007-04-10 | Ixion Biotechnology, Inc. | Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway |
WO2002088335A1 (fr) * | 2001-04-24 | 2002-11-07 | Ajinomoto Co., Inc. | Cellules souches et procede d'extraction de ces cellules |
US7101546B2 (en) | 2001-12-21 | 2006-09-05 | Amcyte, Inc. | In situ maturation of cultured pancreatic stem cells having a specified, intermediate stage of development |
EP1539928A4 (de) | 2002-09-06 | 2006-09-06 | Amcyte Inc | Cd56-positive menschliche adulte pankreatische endokrine vorläuferzellen |
EP1629089A1 (de) * | 2003-06-03 | 2006-03-01 | Organ Recovery Systems, Inc. | Selektion und vermehrung von vorläuferzellen |
JP2007520194A (ja) * | 2003-06-20 | 2007-07-26 | ブレイエ・ユニバージテイト・ブリュッセル | 外分泌膵臓細胞から、膵島ベータ−細胞を生成する方法 |
US20060121512A1 (en) * | 2004-12-02 | 2006-06-08 | Organ Recovery Systems, Inc. | Biological pathways in progenitor cells |
WO2007039986A1 (ja) | 2005-10-05 | 2007-04-12 | Osaka University | 脂肪組織由来細胞から膵内分泌細胞を得る方法 |
KR101452877B1 (ko) * | 2013-08-05 | 2014-10-22 | 사회복지법인 삼성생명공익재단 | 조기-내피전구세포 및 췌도세포를 포함하는 세포이식물의 제조방법 |
JP7081483B2 (ja) * | 2016-04-19 | 2022-06-07 | 凸版印刷株式会社 | 被検化合物の脈管新生阻害活性の評価方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995029988A1 (en) * | 1994-04-28 | 1995-11-09 | University Of Florida Research Foundation, Inc. | In vitro growth of functional islets of langerhans and in vivo uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0605428T5 (da) * | 1991-06-24 | 2003-01-06 | Hcell Technology Inc | Hormonsecernerende pancreasceller opretholdt i langtidskultur |
JP2813467B2 (ja) * | 1993-04-08 | 1998-10-22 | ヒューマン・セル・カルチャーズ・インコーポレーテッド | 細胞培養法および培地 |
-
1996
- 1996-10-23 AU AU74683/96A patent/AU739771B2/en not_active Ceased
- 1996-10-23 JP JP9516734A patent/JPH11514877A/ja not_active Ceased
- 1996-10-23 EP EP96936866A patent/EP0871455A4/de not_active Withdrawn
- 1996-10-23 CA CA002235509A patent/CA2235509A1/en not_active Abandoned
- 1996-10-23 WO PCT/US1996/016952 patent/WO1997015310A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995029988A1 (en) * | 1994-04-28 | 1995-11-09 | University Of Florida Research Foundation, Inc. | In vitro growth of functional islets of langerhans and in vivo uses thereof |
Non-Patent Citations (6)
Title |
---|
CORNELIUS J G ET AL: "In vitro-generation of islets in long-term cultures of pluripotent stem cells from adult mouse pancreas", HORMONE AND METABOLIC RESEARCH, THIEME-STRATTON, STUTTGART, DE, vol. 29, no. 6, 1997, pages 271 - 277, XP000864742, ISSN: 0018-5043 * |
PECK AB & CORNELIUS JG: "In vitro growth of mature pancreatic islets of Langerhans from single, pluripotent stem cells isolated from prediabetic adult pancreas", DIABETES, ABSTRACT BOOK, 55TH ANNUAL MEETING AND SCIENTIFIC SESSIONS, vol. 44, no. Supp. 1, 10 June 1995 (1995-06-10) - 13 June 1995 (1995-06-13), pages A10, XP009006982 * |
PECK AMMON B ET AL: "Pancreatic stem cells: Building blocks for a better surrogate islet to treat type 1 diabetes.", ANNALS OF MEDICINE, vol. 33, no. 3, April 2001 (2001-04-01), pages 186 - 192, XP009006630, ISSN: 0785-3890 * |
PIPELEERS D G: "TRANSPLANTATION OF PURIFIED ISLET CELLS IN DIABETIC RATS. STANDARDIZATION OF ISLET CELL GRAFTS", DIABETES, NEW YORK, NY, US, vol. 40, no. 7, 1 July 1991 (1991-07-01), pages 908 - 919, XP000651349, ISSN: 0012-1797 * |
RAMIYA VIJAYAKUMAR K ET AL: "Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells", NATURE MEDICINE, NATURE AMERICA, NEW YORK, US, vol. 6, no. 3, March 2000 (2000-03-01), pages 278 - 282, XP002228537, ISSN: 1078-8956 * |
See also references of WO9715310A1 * |
Also Published As
Publication number | Publication date |
---|---|
MX9803263A (es) | 1998-09-30 |
CA2235509A1 (en) | 1997-05-01 |
AU739771B2 (en) | 2001-10-18 |
JPH11514877A (ja) | 1999-12-21 |
AU7468396A (en) | 1997-05-15 |
WO1997015310A1 (en) | 1997-05-01 |
EP0871455A1 (de) | 1998-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980525 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030327 |
|
17Q | First examination report despatched |
Effective date: 20031008 |
|
17Q | First examination report despatched |
Effective date: 20031008 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20071228 |