EP0838265B1 - Mécanisme rotatif actionné par la force centrifuge pour des tubes - Google Patents
Mécanisme rotatif actionné par la force centrifuge pour des tubes Download PDFInfo
- Publication number
- EP0838265B1 EP0838265B1 EP97307161A EP97307161A EP0838265B1 EP 0838265 B1 EP0838265 B1 EP 0838265B1 EP 97307161 A EP97307161 A EP 97307161A EP 97307161 A EP97307161 A EP 97307161A EP 0838265 B1 EP0838265 B1 EP 0838265B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- block
- cup
- vessel
- rotor
- movement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/02—Centrifuges consisting of a plurality of separate bowls rotating round an axis situated between the bowls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
- B04B9/10—Control of the drive; Speed regulating
Definitions
- the present invention relates to an apparatus for producing rotation of a vessel about its longitudinal axis during centrifugation.
- the apparatus of the present invention comprises: (a) a cup adapted to receive a vessel, (b) a block surrounding the cup in such a manner that the block may move in a direction parallel to the longitudinal axis when acted on by the centrifugal force, (c) a means for retarding this movement, (d) an oscillating means which encircles the cup (thereby providing for movement in a longitudinal and transverse direction), and (e) a pivoting means which connects the oscillating means to the block.
- centrifuges typically provide for centrifugation by placing a vessel containing the sample to be subjected to centrifugation in a rotor (or other receiver adapted to contain the vessel) attached to the rotating mechanism. When the centrifuge is started, the force is applied in a direction parallel to the longitudinal axis of the vessel, toward the vessel bottom.
- the present invention is directed to an apparatus for producing rotation of a vessel about its longitudinal axis during centrifugation.
- the apparatus comprises: a cup adapted to receive a vessel, surrounded by a block in such a manner that the block may move in a direction parallel to the longitudinal axis when acted upon by the centrifugal force, this movement being slowed by a spring or other retarding means, and the cup also contains a cam or other oscillating means which encircles and preferably sinusoidally encircles, the cup, (thereby providing for movement in a longitudinal and transverse direction) and which is connected to the block by a pivoting means such as a cam follower.
- the entire apparatus is of such a size that it will fit within a centrifuge rotor (or other receiver) without impeding the operation of the apparatus.
- the block will be forced away from the vessel-containing end of the cup upon application of centrifugal force (e.g., by spinning the rotor) until the pivoting means reaches the outer edge of the oscillating means; decreasing the speed of the centrifuge will result in a decrease in centrifugal force, thereby allowing the retarding means to force the block toward the vessel end of the cup until the pivoting means reaches the other edge of the oscillating means, and thereby partially rotating the cup about its longitudinal axis.
- centrifugal force e.g., by spinning the rotor
- Figure 1 presents a depiction of one embodiment of an apparatus of the present invention.
- Figure 2 presents a detail of a preferred oscillating means of this invention.
- Figure 3 presents a depiction of another preferred embodiment of an apparatus of the present invention.
- Figure 4 presents an overhead perspective view of the apparatus of the present invention shown in Figure 3.
- the present invention is directed to an apparatus for producing rotation of a vessel about its longitudinal axis during centrifugation.
- This apparatus adapted for placement in a centrifuge rotor in a centrifuge, comprises:
- the apparatus comprises a cup (2) which has an end adapted to receive the vessel (1).
- the cup (2) is encircled, and is preferably sinusoidally encircled, by an oscillating means (3) which is connected to the block (4) by a pivoting means (5) inside the block (4). Movement of the block (4) in the direction of the centrifugal force is retarded by the retarding means (6).
- the oscillating means (3) is preferably a cam, and the pivoting means (5) is preferably a cam follower.
- a preferred pattern for the oscillating means (3) is shown in Figure 2.
- the retarding means (6) in this embodiment is, preferably, at least one spring.
- the vessel (1) is a small diameter tube, such as those used in the QBCTM instruments marketed and sold by Becton Dickinson and Company.
- Figure 3 shows another embodiment of the present invention.
- the apparatus as shown in Figures 1 and 3 illustrates the mechanical processes of the centrifugally actuated tube rotator mechanism of the present invention.
- the apparatus in each of Figures 1 and 3 uses centrifugal forces to move the associated parts required to achieve rotation of the vessel (1) about the axis of the vessel (1) while the centrifuge rotor is spinning.
- the apparatus is comprised of a block (14) having a pivoting means (13) such as, preferably, a cam follower, an oscillating means such as, preferably, a cam or cam groove (not pictured), a retarding means comprising, preferably, at least two springs (15), and a cup (12) for placement of a vessel (1), wherein the vessel (1) is, preferably, a small diameter tube, or more preferably, a QBCTM tube as described above.
- a pivoting means (13) such as, preferably, a cam follower, an oscillating means such as, preferably, a cam or cam groove (not pictured), a retarding means comprising, preferably, at least two springs (15), and a cup (12) for placement of a vessel (1), wherein the vessel (1) is, preferably, a small diameter tube, or more preferably, a QBCTM tube as described above.
- centrifugal force acts upon the block (14) and the attached cam follower (13) to move the apparatus away from the centrifuge rotor center.
- the cam follower (13) moves along a cam groove (as shown, for example, in Figure 2) on the outer circumference of the cup (12) (the cam groove is not shown in Figure 3) translating the linear movement of the block (14) and the cam follower (13) to a rotational movement of the cup (12).
- the cup (12) is adapted to accept the vessel (1), therefore the rotational movement of the cup (12) translates directly to the vessel (1).
Landscapes
- Centrifugal Separators (AREA)
Claims (10)
- Dispositif servant à entraíner la rotation longitudinale d'un récipient comportant un axe longitudinal, destiné à être agencé dans un rotor de centrifugeuse, ledit dispositif comprenant:(i) une coupelle cylindrique comportant une extrémité destinée à recevoir le récipient lors de l'application d'une force centrifuge produite par la rotation du rotor;(ii) un bloc entourant ladite coupelle, de sorte que le bloc peut se déplacer librement dans une direction parallèle à l'axe longitudinal dudit récipient lors de l'application de ladite force centrifuge;(ii) un moyen pivotant, ledit moyen pivotant étant fixé à l'intérieur dudit bloc;(iv) un moyen oscillant sur ladite coupelle et fixé sur ledit bloc par ledit moyen pivotant, de sorte que le déplacement du bloc dans une direction parallèle à l'axe longitudinal dudit récipient entraíne le déplacement dudit moyen pivotant dans ledit moyen oscillant; et(v) un moyen pour retarder le déplacement dudit bloc,
- Dispositif selon la revendication 1, dans lequel ledit moyen destiné à retarder le déplacement dudit bloc est constitué par au moins un ressort.
- Dispositif selon la revendication 1, dans lequel ledit moyen oscillant sur ladite coupelle est une rainure continue encerclant de manière sinusoïdale ladite coupelle, ledit moyen oscillant assurant le déplacement dans la direction longitudinale et dans la direction transversale.
- Dispositif selon la revendication 1, dans lequel ledit moyen oscillant est une came ou une rainure de came.
- Dispositif selon la revendication 1, dans lequel ledit moyen pivotant est un galet de came.
- Procédé servant à entraíner une rotation longitudinale d'un récipient comportant un axe longitudinal, comprenant un dispositif destiné à être agencé dans un rotor dans une centrifugeuse, ledit dispositif comprenant:(i) une coupelle cylindrique comportant une extrémité destinée à recevoir le récipient lors de l'application d'une force centrifuge produite par la rotation du rotor;(ii) un bloc entourant ladite coupelle, de sorte que le bloc peut se déplacer librement dans une direction parallèle à l'axe longitudinal dudit récipient lors de l'application de ladite force centrifuge;(ii) un moyen pivotant, ledit moyen pivotant étant fixé à l'intérieur dudit bloc;(iv) un moyen oscillant sur ladite coupelle et fixé sur ledit bloc par ledit moyen pivotant, de sorte que le déplacement du bloc dans une direction parallèle à l'axe longitudinal dudit récipient entraíne le déplacement dudit moyen pivotant dans ledit moyen oscillant; et(v) un moyen pour retarder le déplacement dudit bloc, ledit procédé comprenant les étapes ci-dessous:a) agencement dudit dispositif dans ledit rotor de la centrifugeuse;b) agencement d'un récipient dans la coupelle dudit dispositif;c) démarrage de la rotation du rotor de ladite centrifugeuse;d) variation de la vitesse de rotation dudit rotor, de sorte que la réduction de la vitesse du rotor entraíne le déplacement du bloc dudit dispositif dans deux directions, pour entraíner la rotation de ladite coupelle; ete) exécution de la rotation longitudinale dudit récipient.
- Procédé selon la revendication 6, dans lequel ledit moyen destiné à retarder le déplacement dudit bloc est constitué par au moins un ressort.
- Procédé selon la revendication 6, dans lequel ledit moyen oscillant sur ladite coupelle est une rainure continue encerclant de manière sinusoïdale ladite coupelle, ledit moyen oscillant assurant le déplacement dans la direction longitudinale et dans la direction transversale.
- Procédé selon la revendication 6, dans lequel ledit moyen oscillant est une came ou une rainure de came
- Procédé selon la revendication 6, dans lequel ledit moyen pivotant est un galet de came.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72178296A | 1996-09-25 | 1996-09-25 | |
US721782 | 1996-09-25 | ||
1996-11-18 | |||
US91843797A | 1997-08-26 | 1997-08-26 | |
US918437 | 1997-08-26 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0838265A2 EP0838265A2 (fr) | 1998-04-29 |
EP0838265A3 EP0838265A3 (fr) | 1999-03-17 |
EP0838265B1 true EP0838265B1 (fr) | 2002-06-05 |
Family
ID=27110488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97307161A Expired - Lifetime EP0838265B1 (fr) | 1996-09-25 | 1997-09-15 | Mécanisme rotatif actionné par la force centrifuge pour des tubes |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0838265B1 (fr) |
KR (1) | KR19980024909A (fr) |
CA (1) | CA2216056C (fr) |
DE (1) | DE69713025T2 (fr) |
ES (1) | ES2177906T3 (fr) |
SG (1) | SG55488A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6080366A (en) * | 1998-03-02 | 2000-06-27 | Becton, Dickinson And Company | Disposable blood tube holder |
GB2349108B (en) * | 1999-02-09 | 2001-03-28 | Michael Cole | Centrifugal evaporator |
FR2797202B1 (fr) * | 1999-08-02 | 2001-10-26 | Genomic | Equipement pour l'extraction automatique d'acides nucleiques |
US10940491B1 (en) * | 2018-04-25 | 2021-03-09 | Spherical Holdings, Llc | Centrifuge operating with sinusoidal motion |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3850368A (en) * | 1973-02-12 | 1974-11-26 | Kennametal Inc | Apparatus for centrifugal compaction |
GB2190489A (en) * | 1986-02-28 | 1987-11-18 | Automated Diagnostic Systems | Specimen processing system |
-
1997
- 1997-09-15 ES ES97307161T patent/ES2177906T3/es not_active Expired - Lifetime
- 1997-09-15 DE DE69713025T patent/DE69713025T2/de not_active Expired - Fee Related
- 1997-09-15 EP EP97307161A patent/EP0838265B1/fr not_active Expired - Lifetime
- 1997-09-17 CA CA002216056A patent/CA2216056C/fr not_active Expired - Fee Related
- 1997-09-18 SG SG1997003449A patent/SG55488A1/en unknown
- 1997-09-24 KR KR1019970048480A patent/KR19980024909A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69713025D1 (de) | 2002-07-11 |
CA2216056C (fr) | 2000-05-23 |
EP0838265A2 (fr) | 1998-04-29 |
CA2216056A1 (fr) | 1998-03-25 |
EP0838265A3 (fr) | 1999-03-17 |
DE69713025T2 (de) | 2002-12-19 |
ES2177906T3 (es) | 2002-12-16 |
KR19980024909A (ko) | 1998-07-06 |
SG55488A1 (en) | 1998-12-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2770154B1 (fr) | Centrifugeuse a rotor demontable et a dispositif de blocage axial du rotor sur une tete d'entrainement, et rotor pour une telle centrifugeuse | |
DE59703712D1 (de) | Schneckenzentrifuge mit Fliehkraft-Ventil | |
JP2000504993A (ja) | 遠心機ローターを安定化するための装置および方法 | |
EP0838265B1 (fr) | Mécanisme rotatif actionné par la force centrifuge pour des tubes | |
JP2000510220A (ja) | 制動装置 | |
US4832678A (en) | Adapter for a centrifuge tube and a removal tool therefor | |
KR940013556A (ko) | 원심분리기 챔버용 고정시스템 | |
EP0392711A2 (fr) | Moyeu d'entraînement pour centrifugeuse | |
MXPA97007190A (en) | Mechanism of powered rotator tube centrifugame | |
US6183408B1 (en) | Rotor shaft assembly having non-linear stiffness | |
US4190195A (en) | Hanger design for a swinging centrifuge rotor | |
EP0109410A1 (fr) | Palier stabilisateur pour centrifugeuse | |
US6063017A (en) | Method and apparatus capable of preventing vertical forces during rotor failure | |
MXPA98002912A (en) | Mechanism of powered rotator tube centrifugame | |
JPH11500662A (ja) | スイングバケット式遠心分離機ローターに使用するバケット | |
SU1195203A1 (ru) | АВТОБАЛАНСИРУЮЩЕЕ УСТРОЙСТВО для закритической частоты вращения | |
EP0224955B1 (fr) | Centrifugeuse, en particulier à usage biomédical | |
JP2839588B2 (ja) | 連続遠心分離装置 | |
MX9707190A (es) | Mecanismo de tubo rotador accionado centrifugamente. | |
SU1650256A1 (ru) | Способ автоматической балансировки центрифуги | |
RU1771893C (ru) | Фреза | |
CA2210332A1 (fr) | Machine d'actionnement basee sur la force centrifuge | |
JPH10249240A (ja) | 遠心機用の管回転装置及び同方法 | |
SU1065102A1 (ru) | Центробежный цанговый патрон | |
SU1697208A1 (ru) | Ротор высокоскоростной электрической машины |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): BE CH DE ES FR GB IT LI |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;RO;SI |
|
PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;RO;SI |
|
17P | Request for examination filed |
Effective date: 19990428 |
|
AKX | Designation fees paid |
Free format text: BE CH DE ES FR GB IT LI |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
17Q | First examination report despatched |
Effective date: 20010613 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): BE CH DE ES FR GB IT LI |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REF | Corresponds to: |
Ref document number: 69713025 Country of ref document: DE Date of ref document: 20020711 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: RITSCHER & PARTNER AG PATENTANWAELTE |
|
ET | Fr: translation filed | ||
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2177906 Country of ref document: ES Kind code of ref document: T3 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20030306 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20060928 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 20070926 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20070926 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20070926 Year of fee payment: 11 Ref country code: DE Payment date: 20071031 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20071025 Year of fee payment: 11 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PCAR Free format text: RITSCHER & PARTNER AG;RESIRAIN 1;8125 ZOLLIKERBERG (CH) |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20070917 Year of fee payment: 11 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070930 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070930 |
|
BERE | Be: lapsed |
Owner name: *BECTON DICKINSON AND CY Effective date: 20080930 |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20080915 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20090529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080930 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080915 Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090401 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080930 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20080916 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080915 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080916 |