EP0838265B1 - Mécanisme rotatif actionné par la force centrifuge pour des tubes - Google Patents

Mécanisme rotatif actionné par la force centrifuge pour des tubes Download PDF

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Publication number
EP0838265B1
EP0838265B1 EP97307161A EP97307161A EP0838265B1 EP 0838265 B1 EP0838265 B1 EP 0838265B1 EP 97307161 A EP97307161 A EP 97307161A EP 97307161 A EP97307161 A EP 97307161A EP 0838265 B1 EP0838265 B1 EP 0838265B1
Authority
EP
European Patent Office
Prior art keywords
block
cup
vessel
rotor
movement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP97307161A
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German (de)
English (en)
Other versions
EP0838265A2 (fr
EP0838265A3 (fr
Inventor
Michael R. Walters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of EP0838265A2 publication Critical patent/EP0838265A2/fr
Publication of EP0838265A3 publication Critical patent/EP0838265A3/fr
Application granted granted Critical
Publication of EP0838265B1 publication Critical patent/EP0838265B1/fr
Anticipated expiration legal-status Critical
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/02—Centrifuges consisting of a plurality of separate bowls rotating round an axis situated between the bowls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/10—Control of the drive; Speed regulating

Definitions

  • the present invention relates to an apparatus for producing rotation of a vessel about its longitudinal axis during centrifugation.
  • the apparatus of the present invention comprises: (a) a cup adapted to receive a vessel, (b) a block surrounding the cup in such a manner that the block may move in a direction parallel to the longitudinal axis when acted on by the centrifugal force, (c) a means for retarding this movement, (d) an oscillating means which encircles the cup (thereby providing for movement in a longitudinal and transverse direction), and (e) a pivoting means which connects the oscillating means to the block.
  • centrifuges typically provide for centrifugation by placing a vessel containing the sample to be subjected to centrifugation in a rotor (or other receiver adapted to contain the vessel) attached to the rotating mechanism. When the centrifuge is started, the force is applied in a direction parallel to the longitudinal axis of the vessel, toward the vessel bottom.
  • the present invention is directed to an apparatus for producing rotation of a vessel about its longitudinal axis during centrifugation.
  • the apparatus comprises: a cup adapted to receive a vessel, surrounded by a block in such a manner that the block may move in a direction parallel to the longitudinal axis when acted upon by the centrifugal force, this movement being slowed by a spring or other retarding means, and the cup also contains a cam or other oscillating means which encircles and preferably sinusoidally encircles, the cup, (thereby providing for movement in a longitudinal and transverse direction) and which is connected to the block by a pivoting means such as a cam follower.
  • the entire apparatus is of such a size that it will fit within a centrifuge rotor (or other receiver) without impeding the operation of the apparatus.
  • the block will be forced away from the vessel-containing end of the cup upon application of centrifugal force (e.g., by spinning the rotor) until the pivoting means reaches the outer edge of the oscillating means; decreasing the speed of the centrifuge will result in a decrease in centrifugal force, thereby allowing the retarding means to force the block toward the vessel end of the cup until the pivoting means reaches the other edge of the oscillating means, and thereby partially rotating the cup about its longitudinal axis.
  • centrifugal force e.g., by spinning the rotor
  • Figure 1 presents a depiction of one embodiment of an apparatus of the present invention.
  • Figure 2 presents a detail of a preferred oscillating means of this invention.
  • Figure 3 presents a depiction of another preferred embodiment of an apparatus of the present invention.
  • Figure 4 presents an overhead perspective view of the apparatus of the present invention shown in Figure 3.
  • the present invention is directed to an apparatus for producing rotation of a vessel about its longitudinal axis during centrifugation.
  • This apparatus adapted for placement in a centrifuge rotor in a centrifuge, comprises:
  • the apparatus comprises a cup (2) which has an end adapted to receive the vessel (1).
  • the cup (2) is encircled, and is preferably sinusoidally encircled, by an oscillating means (3) which is connected to the block (4) by a pivoting means (5) inside the block (4). Movement of the block (4) in the direction of the centrifugal force is retarded by the retarding means (6).
  • the oscillating means (3) is preferably a cam, and the pivoting means (5) is preferably a cam follower.
  • a preferred pattern for the oscillating means (3) is shown in Figure 2.
  • the retarding means (6) in this embodiment is, preferably, at least one spring.
  • the vessel (1) is a small diameter tube, such as those used in the QBCTM instruments marketed and sold by Becton Dickinson and Company.
  • Figure 3 shows another embodiment of the present invention.
  • the apparatus as shown in Figures 1 and 3 illustrates the mechanical processes of the centrifugally actuated tube rotator mechanism of the present invention.
  • the apparatus in each of Figures 1 and 3 uses centrifugal forces to move the associated parts required to achieve rotation of the vessel (1) about the axis of the vessel (1) while the centrifuge rotor is spinning.
  • the apparatus is comprised of a block (14) having a pivoting means (13) such as, preferably, a cam follower, an oscillating means such as, preferably, a cam or cam groove (not pictured), a retarding means comprising, preferably, at least two springs (15), and a cup (12) for placement of a vessel (1), wherein the vessel (1) is, preferably, a small diameter tube, or more preferably, a QBCTM tube as described above.
  • a pivoting means (13) such as, preferably, a cam follower, an oscillating means such as, preferably, a cam or cam groove (not pictured), a retarding means comprising, preferably, at least two springs (15), and a cup (12) for placement of a vessel (1), wherein the vessel (1) is, preferably, a small diameter tube, or more preferably, a QBCTM tube as described above.
  • centrifugal force acts upon the block (14) and the attached cam follower (13) to move the apparatus away from the centrifuge rotor center.
  • the cam follower (13) moves along a cam groove (as shown, for example, in Figure 2) on the outer circumference of the cup (12) (the cam groove is not shown in Figure 3) translating the linear movement of the block (14) and the cam follower (13) to a rotational movement of the cup (12).
  • the cup (12) is adapted to accept the vessel (1), therefore the rotational movement of the cup (12) translates directly to the vessel (1).

Landscapes

  • Centrifugal Separators (AREA)

Claims (10)

  1. Dispositif servant à entraíner la rotation longitudinale d'un récipient comportant un axe longitudinal, destiné à être agencé dans un rotor de centrifugeuse, ledit dispositif comprenant:
    (i) une coupelle cylindrique comportant une extrémité destinée à recevoir le récipient lors de l'application d'une force centrifuge produite par la rotation du rotor;
    (ii) un bloc entourant ladite coupelle, de sorte que le bloc peut se déplacer librement dans une direction parallèle à l'axe longitudinal dudit récipient lors de l'application de ladite force centrifuge;
    (ii) un moyen pivotant, ledit moyen pivotant étant fixé à l'intérieur dudit bloc;
    (iv) un moyen oscillant sur ladite coupelle et fixé sur ledit bloc par ledit moyen pivotant, de sorte que le déplacement du bloc dans une direction parallèle à l'axe longitudinal dudit récipient entraíne le déplacement dudit moyen pivotant dans ledit moyen oscillant; et
    (v) un moyen pour retarder le déplacement dudit bloc,
       ladite rotation longitudinale étant assurée par variation de la vitesse de rotation dudit rotor, de sorte que le bloc est déplacé dans les deux directions, entraínant ainsi la rotation de ladite coupelle destinée à recevoir ledit récipient.
  2. Dispositif selon la revendication 1, dans lequel ledit moyen destiné à retarder le déplacement dudit bloc est constitué par au moins un ressort.
  3. Dispositif selon la revendication 1, dans lequel ledit moyen oscillant sur ladite coupelle est une rainure continue encerclant de manière sinusoïdale ladite coupelle, ledit moyen oscillant assurant le déplacement dans la direction longitudinale et dans la direction transversale.
  4. Dispositif selon la revendication 1, dans lequel ledit moyen oscillant est une came ou une rainure de came.
  5. Dispositif selon la revendication 1, dans lequel ledit moyen pivotant est un galet de came.
  6. Procédé servant à entraíner une rotation longitudinale d'un récipient comportant un axe longitudinal, comprenant un dispositif destiné à être agencé dans un rotor dans une centrifugeuse, ledit dispositif comprenant:
    (i) une coupelle cylindrique comportant une extrémité destinée à recevoir le récipient lors de l'application d'une force centrifuge produite par la rotation du rotor;
    (ii) un bloc entourant ladite coupelle, de sorte que le bloc peut se déplacer librement dans une direction parallèle à l'axe longitudinal dudit récipient lors de l'application de ladite force centrifuge;
    (ii) un moyen pivotant, ledit moyen pivotant étant fixé à l'intérieur dudit bloc;
    (iv) un moyen oscillant sur ladite coupelle et fixé sur ledit bloc par ledit moyen pivotant, de sorte que le déplacement du bloc dans une direction parallèle à l'axe longitudinal dudit récipient entraíne le déplacement dudit moyen pivotant dans ledit moyen oscillant; et
    (v) un moyen pour retarder le déplacement dudit bloc, ledit procédé comprenant les étapes ci-dessous:
    a) agencement dudit dispositif dans ledit rotor de la centrifugeuse;
    b) agencement d'un récipient dans la coupelle dudit dispositif;
    c) démarrage de la rotation du rotor de ladite centrifugeuse;
    d) variation de la vitesse de rotation dudit rotor, de sorte que la réduction de la vitesse du rotor entraíne le déplacement du bloc dudit dispositif dans deux directions, pour entraíner la rotation de ladite coupelle; et
    e) exécution de la rotation longitudinale dudit récipient.
  7. Procédé selon la revendication 6, dans lequel ledit moyen destiné à retarder le déplacement dudit bloc est constitué par au moins un ressort.
  8. Procédé selon la revendication 6, dans lequel ledit moyen oscillant sur ladite coupelle est une rainure continue encerclant de manière sinusoïdale ladite coupelle, ledit moyen oscillant assurant le déplacement dans la direction longitudinale et dans la direction transversale.
  9. Procédé selon la revendication 6, dans lequel ledit moyen oscillant est une came ou une rainure de came
  10. Procédé selon la revendication 6, dans lequel ledit moyen pivotant est un galet de came.
EP97307161A 1996-09-25 1997-09-15 Mécanisme rotatif actionné par la force centrifuge pour des tubes Expired - Lifetime EP0838265B1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US721782 1985-04-10
US72178296A 1996-09-25 1996-09-25
US91843797A 1997-08-26 1997-08-26
US918437 1997-08-26
2000-02-22

Publications (3)

Publication Number Publication Date
EP0838265A2 EP0838265A2 (fr) 1998-04-29
EP0838265A3 EP0838265A3 (fr) 1999-03-17
EP0838265B1 true EP0838265B1 (fr) 2002-06-05

Family

ID=27110488

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97307161A Expired - Lifetime EP0838265B1 (fr) 1996-09-25 1997-09-15 Mécanisme rotatif actionné par la force centrifuge pour des tubes

Country Status (6)

Country Link
EP (1) EP0838265B1 (fr)
KR (1) KR19980024909A (fr)
CA (1) CA2216056C (fr)
DE (1) DE69713025T2 (fr)
ES (1) ES2177906T3 (fr)
SG (1) SG55488A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080366A (en) * 1998-03-02 2000-06-27 Becton, Dickinson And Company Disposable blood tube holder
GB2349108B (en) * 1999-02-09 2001-03-28 Michael Cole Centrifugal evaporator
FR2797202B1 (fr) * 1999-08-02 2001-10-26 Genomic Equipement pour l'extraction automatique d'acides nucleiques
US10940491B1 (en) * 2018-04-25 2021-03-09 Spherical Holdings, Llc Centrifuge operating with sinusoidal motion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3850368A (en) * 1973-02-12 1974-11-26 Kennametal Inc Apparatus for centrifugal compaction
GB2190489A (en) * 1986-02-28 1987-11-18 Automated Diagnostic Systems Specimen processing system

Also Published As

Publication number Publication date
DE69713025D1 (de) 2002-07-11
SG55488A1 (en) 1998-12-21
CA2216056A1 (fr) 1998-03-25
DE69713025T2 (de) 2002-12-19
EP0838265A2 (fr) 1998-04-29
EP0838265A3 (fr) 1999-03-17
ES2177906T3 (es) 2002-12-16
CA2216056C (fr) 2000-05-23
KR19980024909A (ko) 1998-07-06

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