EP0830367A4 - HIGH AFFINE NUCLEIC ACID LIGANDS BY CYTOKINE - Google Patents
HIGH AFFINE NUCLEIC ACID LIGANDS BY CYTOKINEInfo
- Publication number
- EP0830367A4 EP0830367A4 EP96919214A EP96919214A EP0830367A4 EP 0830367 A4 EP0830367 A4 EP 0830367A4 EP 96919214 A EP96919214 A EP 96919214A EP 96919214 A EP96919214 A EP 96919214A EP 0830367 A4 EP0830367 A4 EP 0830367A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cytokines
- nucleic acid
- acid ligands
- affinity nucleic
- affinity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/322—2'-R Modification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08010881A EP2011503A3 (en) | 1995-06-07 | 1996-06-04 | High affinity nucleic acid ligands of cytokines |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/481,710 US6028186A (en) | 1991-06-10 | 1995-06-07 | High affinity nucleic acid ligands of cytokines |
US477527 | 1995-06-07 | ||
US08/477,527 US5972599A (en) | 1990-06-11 | 1995-06-07 | High affinity nucleic acid ligands of cytokines |
US481710 | 1995-06-07 | ||
PCT/US1996/009537 WO1996040717A1 (en) | 1995-06-07 | 1996-06-04 | High-affinity nucleic acid ligands of cytokines |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08010881A Division EP2011503A3 (en) | 1995-06-07 | 1996-06-04 | High affinity nucleic acid ligands of cytokines |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0830367A1 EP0830367A1 (en) | 1998-03-25 |
EP0830367A4 true EP0830367A4 (en) | 2003-03-05 |
Family
ID=27045583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96919214A Withdrawn EP0830367A4 (en) | 1995-06-07 | 1996-06-04 | HIGH AFFINE NUCLEIC ACID LIGANDS BY CYTOKINE |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0830367A4 (ja) |
JP (1) | JPH11507529A (ja) |
CA (1) | CA2223003A1 (ja) |
WO (1) | WO1996040717A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2430394T3 (es) * | 1997-12-31 | 2013-11-20 | University Of Iowa Research Foundation | Uso de agentes biológicos parasitarios para la prevención y el control de la enfermedad inflamatoria intestinal |
US6171795B1 (en) * | 1999-07-29 | 2001-01-09 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to CD40ligand |
JP3978187B2 (ja) * | 2002-03-19 | 2007-09-19 | 富士通株式会社 | 機能性分子及びその製造方法 |
US9303262B2 (en) | 2002-09-17 | 2016-04-05 | Archemix Llc | Methods for identifying aptamer regulators |
US20070066550A1 (en) * | 2004-03-05 | 2007-03-22 | Diener John L | Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics |
EP3530738A4 (en) * | 2016-10-24 | 2020-06-03 | KIM, Sung-Chun | TNF-ALPHA BINDING APTAMER, AND THERAPEUTIC USE |
JP7397446B2 (ja) * | 2018-04-20 | 2023-12-13 | 中央研究院 | Tnf関連炎症性疾患を治療または診断するtnf指向性アプタマーおよびその使用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995007364A1 (en) * | 1993-09-08 | 1995-03-16 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands and improved methods for producing the same |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5270163A (en) * | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
AU1435492A (en) * | 1991-02-21 | 1992-09-15 | Gilead Sciences, Inc. | Aptamer specific for biomolecules and method of making |
-
1996
- 1996-06-04 CA CA002223003A patent/CA2223003A1/en not_active Abandoned
- 1996-06-04 WO PCT/US1996/009537 patent/WO1996040717A1/en active Application Filing
- 1996-06-04 JP JP9501840A patent/JPH11507529A/ja active Pending
- 1996-06-04 EP EP96919214A patent/EP0830367A4/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995007364A1 (en) * | 1993-09-08 | 1995-03-16 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands and improved methods for producing the same |
Non-Patent Citations (3)
Title |
---|
BUDINGER T F ET AL: "New approaches to targeting arthritis with radiopharmaceuticals.", THE JOURNAL OF RHEUMATOLOGY. SUPPLEMENT. CANADA FEB 1995, vol. 43, February 1995 (1995-02-01), pages 62 - 67, XP001098388, ISSN: 0380-0903 * |
JELLINEK D ET AL: "INHIBITION OF RECEPTOR BINDING BY HIGH-AFFINITY RNA LIGANDS TO VASCULAR ENDOTHELIAL GROWTH FACTOR", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 34, no. 33, 30 August 1994 (1994-08-30), pages 10450 - 10456, XP001084739, ISSN: 0006-2960 * |
See also references of WO9640717A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0830367A1 (en) | 1998-03-25 |
JPH11507529A (ja) | 1999-07-06 |
CA2223003A1 (en) | 1996-12-19 |
WO1996040717A1 (en) | 1996-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19971202 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 07H 21/02 A, 7C 07H 21/04 B, 7C 12P 19/34 B, 7C 12Q 1/68 B, 7C 12N 15/10 B, 7C 07H 21/00 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030121 |
|
17Q | First examination report despatched |
Effective date: 20030414 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: GILEAD SCIENCES, INC. |
|
17Q | First examination report despatched |
Effective date: 20030414 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080703 |