EP0779812A4 - METHOD FOR TREATING OSTEOPOROSIS USING BONE-ACTIVE PHOSPHONATES AND PARATHORMONE - Google Patents

METHOD FOR TREATING OSTEOPOROSIS USING BONE-ACTIVE PHOSPHONATES AND PARATHORMONE

Info

Publication number
EP0779812A4
EP0779812A4 EP95932426A EP95932426A EP0779812A4 EP 0779812 A4 EP0779812 A4 EP 0779812A4 EP 95932426 A EP95932426 A EP 95932426A EP 95932426 A EP95932426 A EP 95932426A EP 0779812 A4 EP0779812 A4 EP 0779812A4
Authority
EP
European Patent Office
Prior art keywords
osteoporosis
treatment
methods
parathyroid hormone
bone active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP95932426A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0779812A1 (en
Inventor
John Althorp Bevan
Ann Dunbar Geddes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of EP0779812A1 publication Critical patent/EP0779812A1/en
Publication of EP0779812A4 publication Critical patent/EP0779812A4/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP95932426A 1994-09-09 1995-09-06 METHOD FOR TREATING OSTEOPOROSIS USING BONE-ACTIVE PHOSPHONATES AND PARATHORMONE Ceased EP0779812A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30392594A 1994-09-09 1994-09-09
US303925 1994-09-09
PCT/US1995/011335 WO1996007417A1 (en) 1994-09-09 1995-09-06 Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone

Publications (2)

Publication Number Publication Date
EP0779812A1 EP0779812A1 (en) 1997-06-25
EP0779812A4 true EP0779812A4 (en) 1997-09-10

Family

ID=23174289

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95932426A Ceased EP0779812A4 (en) 1994-09-09 1995-09-06 METHOD FOR TREATING OSTEOPOROSIS USING BONE-ACTIVE PHOSPHONATES AND PARATHORMONE

Country Status (8)

Country Link
EP (1) EP0779812A4 (ko)
JP (1) JPH10505090A (ko)
KR (1) KR970705400A (ko)
CN (1) CN1157565A (ko)
AU (1) AU686458B2 (ko)
CA (1) CA2199252A1 (ko)
IL (1) IL115224A0 (ko)
WO (1) WO1996007417A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702401D0 (sv) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
ES2394211T3 (es) 2000-06-20 2013-01-23 Novartis Ag Procedimiento de administración de bifosfonatos
JP2009515535A (ja) 2005-11-10 2009-04-16 ボード オブ コントロール オブ ミシガン テクノロジカル ユニヴァーシティー クロクマの副甲状腺ホルモン及びクロクマの副甲状腺ホルモンを使用する方法
AU2010278860B2 (en) 2009-07-31 2016-05-26 Thar Pharma, Llc Crystallization method and bioavailability
US9169279B2 (en) 2009-07-31 2015-10-27 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
US20160016982A1 (en) 2009-07-31 2016-01-21 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
EP2509996A1 (en) 2009-12-07 2012-10-17 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US9340565B2 (en) 2010-11-24 2016-05-17 Thar Pharmaceuticals, Inc. Crystalline forms
US10195218B2 (en) 2016-05-31 2019-02-05 Grunenthal Gmbh Crystallization method and bioavailability

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0273514A1 (en) * 1986-12-19 1988-07-06 Norwich Eaton Pharmaceuticals, Inc. Novel bicyclic diphosphonate compounds and pharmaceutical compositions
US4833125A (en) * 1986-12-05 1989-05-23 The General Hospital Corporation Method of increasing bone mass
EP0381296A1 (en) * 1984-04-30 1990-08-08 THE PROCTER & GAMBLE COMPANY Kit for use in the treatment of osteoporosis
WO1994021242A1 (en) * 1993-03-19 1994-09-29 The Procter & Gamble Company Methods for the treatment of osteoporosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812304A (en) * 1984-12-21 1989-03-14 The Procter & Gamble Company Treatment of osteoporosis
SK74594A3 (en) * 1991-12-17 1995-01-12 Procter & Gamble Pharma Treatment for treating of osteoporosis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0381296A1 (en) * 1984-04-30 1990-08-08 THE PROCTER & GAMBLE COMPANY Kit for use in the treatment of osteoporosis
US4833125A (en) * 1986-12-05 1989-05-23 The General Hospital Corporation Method of increasing bone mass
EP0273514A1 (en) * 1986-12-19 1988-07-06 Norwich Eaton Pharmaceuticals, Inc. Novel bicyclic diphosphonate compounds and pharmaceutical compositions
WO1994021242A1 (en) * 1993-03-19 1994-09-29 The Procter & Gamble Company Methods for the treatment of osteoporosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9607417A1 *

Also Published As

Publication number Publication date
AU3547595A (en) 1996-03-27
CN1157565A (zh) 1997-08-20
JPH10505090A (ja) 1998-05-19
KR970705400A (ko) 1997-10-09
EP0779812A1 (en) 1997-06-25
WO1996007417A1 (en) 1996-03-14
IL115224A0 (en) 1995-12-31
CA2199252A1 (en) 1996-03-14
AU686458B2 (en) 1998-02-05

Similar Documents

Publication Publication Date Title
HU9401798D0 (en) Methods for the treatment of osteoporosis using bisphonates and parathyroid hormone
LT99010A (en) Parathyroid hormone analogues for the treatment of osteoporosis
GB9407135D0 (en) Treatment of osteoporosis
PL339449A1 (en) Treatment of bone fractures involving the use of pthrp analogues
ZA988886B (en) Formulation for treatment of osteoporosis
EP0767624A4 (en) DEVICES AND METHOD FOR PREPARING BONE / TISSUE
EP0961613A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF BONE RESORPTION DISORDERS, INCLUDING OSTEOPOROSIS
IL132159A0 (en) Plant extracts for the treatment of increased bone resorption
PL328831A1 (en) Combined treatment of osteoporosis
HK1030545A1 (en) Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture
IL112455A0 (en) Combination treatment for osteoporosis
PL321835A1 (en) Method of reducing the risk of non-vertebral bone fracture
IL104940A0 (en) Method and composition for the treatment of osteoporosis
EP0779812A4 (en) METHOD FOR TREATING OSTEOPOROSIS USING BONE-ACTIVE PHOSPHONATES AND PARATHORMONE
GB9808936D0 (en) Combination therapy for the prevention and treatment of osteoporosis
GB9421362D0 (en) Orthopaedic human bone demonstational aid
PL321836A1 (en) Method of reducing the risk of vertebral bone fracture
HUP9904049A3 (en) Growth hormone component and bone anti-resorptive agent in cyclic(coherence)treatment of osteoporosis
EP0779813A4 (en) PHOSPHONATES AND PARATHORMONE AGAINST OSTEOPOROSIS
EP0981545A4 (en) TREATMENT OF OSTEOPOROSIS
ZA961859B (en) Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone
HU9501779D0 (en) Agents for treating metabolic bone diseases
PL320564A1 (en) Therapeutic set for treating osteoporosis
IL120955A0 (en) Treatment of osteoporosis
EP0692965A4 (en) METHOD AND COMPOSITION FOR THE TREATMENT OF OSTEOPOROSIS

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19970403

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19970721

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

17Q First examination report despatched

Effective date: 19970901

GRAG Despatch of communication of intention to grant

Free format text: ORIGINAL CODE: EPIDOS AGRA

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20000319