EP0777741A4 - Biocapteur et procede destines a la detection par luminescence electrophotochimique d'acides nucleiques adsorbes sur une surface solide - Google Patents
Biocapteur et procede destines a la detection par luminescence electrophotochimique d'acides nucleiques adsorbes sur une surface solideInfo
- Publication number
- EP0777741A4 EP0777741A4 EP95930881A EP95930881A EP0777741A4 EP 0777741 A4 EP0777741 A4 EP 0777741A4 EP 95930881 A EP95930881 A EP 95930881A EP 95930881 A EP95930881 A EP 95930881A EP 0777741 A4 EP0777741 A4 EP 0777741A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- biosensor
- nucleic acid
- solid surface
- chemiluminescent detection
- acid adsorbed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29663094A | 1994-08-26 | 1994-08-26 | |
US296630 | 1994-08-26 | ||
PCT/US1995/010630 WO1996006946A1 (fr) | 1994-08-26 | 1995-08-25 | Biocapteur et procede destines a la detection par luminescence electrophotochimique d'acides nucleiques adsorbes sur une surface solide |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0777741A1 EP0777741A1 (fr) | 1997-06-11 |
EP0777741A4 true EP0777741A4 (fr) | 1999-01-13 |
Family
ID=23142843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95930881A Withdrawn EP0777741A4 (fr) | 1994-08-26 | 1995-08-25 | Biocapteur et procede destines a la detection par luminescence electrophotochimique d'acides nucleiques adsorbes sur une surface solide |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0777741A4 (fr) |
JP (1) | JPH10509025A (fr) |
AU (1) | AU703344B2 (fr) |
CA (1) | CA2198489A1 (fr) |
WO (1) | WO1996006946A1 (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5786141A (en) * | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
BR9607193B1 (pt) * | 1995-03-10 | 2009-01-13 | teste de eletroquimioluscÊncia multi-especÍfico de méltiplos conjuntos. | |
US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
FR2762013B1 (fr) * | 1997-04-09 | 1999-06-04 | Cis Bio Int | Systemes de detection d'hybridation d'acides nucleiques, leur procede de preparation et leurs utilisations |
US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
AU779220B2 (en) | 1999-07-26 | 2005-01-13 | Clinical Micro Sensors, Inc. | Sequence determination of nucleic acids using electronic detection |
US6518024B2 (en) | 1999-12-13 | 2003-02-11 | Motorola, Inc. | Electrochemical detection of single base extension |
AU2907201A (en) * | 1999-12-09 | 2001-06-18 | Motorola, Inc. | Methods and compositions relating to electrical detection of nucleic acid reactions |
US6824669B1 (en) | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
US6706479B2 (en) * | 2000-10-05 | 2004-03-16 | Virginia Tech Intellectual Properties, Inc. | Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips |
US7138121B2 (en) | 2003-01-23 | 2006-11-21 | Spangler Brenda D | Biosensors utilizing dendrimer-immobilized ligands and there use thereof |
US7741033B2 (en) * | 2003-05-13 | 2010-06-22 | Trustees Of Boston College | Electrocatalytic nucleic acid hybridization detection |
ATE445715T1 (de) | 2003-05-13 | 2009-10-15 | Trustees Boston College | Elektrokatalytischer nukleinsäurehybridisierungsnachweis |
JPWO2006075497A1 (ja) * | 2004-12-21 | 2008-06-12 | 国立大学法人京都大学 | プローブユニット、ヌクレオチド領域の同定装置、及びヌクレオチド領域の同定方法 |
ES2732948T3 (es) | 2008-09-02 | 2019-11-26 | Governing Council Univ Toronto | Métodos que utilizan microelectrodos y dispositivos biosensores que incorporan los mismos |
ES2704685T3 (es) | 2011-01-11 | 2019-03-19 | Governing Council Univ Toronto | Método para la detección de proteínas |
WO2012122564A2 (fr) | 2011-03-10 | 2012-09-13 | Xagenic, Inc. | Dispositifs et méthodes de diagnostic et de préparation d'échantillons |
JP6979941B2 (ja) | 2015-08-20 | 2021-12-15 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Peg化分析物特異的結合剤を用いた粒子に基づくイムノアッセイ |
CN108780092A (zh) | 2016-03-07 | 2018-11-09 | 豪夫迈·罗氏有限公司 | 抗p53抗体的检测 |
CN110234995A (zh) | 2017-02-02 | 2019-09-13 | 豪夫迈·罗氏有限公司 | 使用至少两种聚乙二醇化的分析物特异性结合试剂的免疫测定 |
EP3781600A1 (fr) | 2018-04-18 | 2021-02-24 | F. Hoffmann-La Roche AG | Nouveaux anticorps anti-thymidine kinase |
WO2020043868A1 (fr) | 2018-08-31 | 2020-03-05 | F. Hoffmann-La Roche Ag | Thymidine kinase (tk-1) dans la détermination d'indices de pronostic pour le dlbcl |
KR20220016210A (ko) | 2019-07-22 | 2022-02-08 | 에프. 호프만-라 로슈 아게 | 자궁내막증의 비-침습적 진단용 혈액 생물표지자로써 s100a9 |
CN114144671A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100a12作为用于子宫内膜异位症的非侵入性诊断的血液生物标志物 |
WO2021013784A1 (fr) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a8 utilisée en tant que biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
EP4004555A1 (fr) | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a6 en tant que biomarqueur du sang pour le diagnostic non invasif de l'endométriose |
JP7315780B2 (ja) | 2019-07-22 | 2023-07-26 | エフ. ホフマン-ラ ロシュ アーゲー | 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのサブスタンスp |
JP2023502360A (ja) | 2019-11-15 | 2023-01-24 | エフ.ホフマン-ラ ロシュ アーゲー | 患者試料における質量分析測定のためのβ-ラクタム抗生物質の誘導体化 |
CN111272742B (zh) * | 2020-03-06 | 2022-11-08 | 安徽大学 | 基于金属有机凝胶复合材料和金属有机框架的电致化学发光传感器及其制备和检测方法 |
WO2022090455A1 (fr) | 2020-11-02 | 2022-05-05 | F. Hoffmann-La Roche Ag | Anticorps nucléocapsidiques du sars-cov-2 |
WO2022207628A1 (fr) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf comme biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
EP4314838A1 (fr) | 2021-04-01 | 2024-02-07 | F. Hoffmann-La Roche AG | Psp94 utilisée en tant que biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
CN117337394A (zh) | 2021-05-17 | 2024-01-02 | 豪夫迈·罗氏有限公司 | sFRP4作为血液生物标志物用于子宫腺肌病的非侵入性诊断 |
WO2023072904A1 (fr) | 2021-10-26 | 2023-05-04 | F. Hoffmann-La Roche Ag | Anticorps monoclonaux spécifiques du rbd du sars-cov-2 |
WO2023131594A1 (fr) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Dérivatisation de composés dans des échantillons de patients pour la pharmacovigilance thérapeutique (tdm) |
WO2023247752A1 (fr) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Procédé de diagnostic de l'endométriose et de classification du stade de l'endométriose |
WO2024017985A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Protéine 1 de liaison au facteur de croissance des fibroblastes (fgfbp1) utilisée en tant que biomarqueur (sanguin) pour le diagnostic du syndrome des ovaires polykystiques |
WO2024017983A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Protéine de type météorine (metrnl) utilisée en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques |
WO2024017982A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriène a4 hydrolase (lta4h) en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques |
CN115414930B (zh) * | 2022-08-26 | 2023-10-31 | 重庆医科大学 | Ru(bpy)32+阳极或阴极共反应物及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1258580A (fr) * | 1967-12-28 | 1971-12-30 | ||
US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US5124022A (en) * | 1989-08-23 | 1992-06-23 | Aluminum Company Of America | Electrolytic capacitor and method of making same |
US5019343A (en) * | 1989-12-15 | 1991-05-28 | W. R. Grace & Co.-Conn. | Control of corrosion in aqueous systems using certain phosphonomethyl amines |
US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
-
1995
- 1995-08-25 AU AU34103/95A patent/AU703344B2/en not_active Ceased
- 1995-08-25 CA CA002198489A patent/CA2198489A1/fr not_active Abandoned
- 1995-08-25 JP JP8508822A patent/JPH10509025A/ja active Pending
- 1995-08-25 WO PCT/US1995/010630 patent/WO1996006946A1/fr not_active Application Discontinuation
- 1995-08-25 EP EP95930881A patent/EP0777741A4/fr not_active Withdrawn
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO9606946A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU3410395A (en) | 1996-03-22 |
EP0777741A1 (fr) | 1997-06-11 |
CA2198489A1 (fr) | 1996-03-07 |
WO1996006946A1 (fr) | 1996-03-07 |
AU703344B2 (en) | 1999-03-25 |
JPH10509025A (ja) | 1998-09-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 19970307 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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AX | Request for extension of the european patent |
Free format text: LT PAYMENT 970307;LV PAYMENT 970307;SI PAYMENT 970307 |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: IGEN INTERNATIONAL, INC. |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 19981202 |
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AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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17Q | First examination report despatched |
Effective date: 19990105 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20000718 |
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PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 19981105 Year of fee payment: 4 |