JPH10509025A - 固体表面に吸着された核酸の電気的に発生した化学ルミネッセンス性検出のためのバイオセンサーおよび方法 - Google Patents
固体表面に吸着された核酸の電気的に発生した化学ルミネッセンス性検出のためのバイオセンサーおよび方法Info
- Publication number
- JPH10509025A JPH10509025A JP8508822A JP50882296A JPH10509025A JP H10509025 A JPH10509025 A JP H10509025A JP 8508822 A JP8508822 A JP 8508822A JP 50882296 A JP50882296 A JP 50882296A JP H10509025 A JPH10509025 A JP H10509025A
- Authority
- JP
- Japan
- Prior art keywords
- dna
- nucleic acid
- film
- metal
- electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29663094A | 1994-08-26 | 1994-08-26 | |
| US08/296,630 | 1994-08-26 | ||
| PCT/US1995/010630 WO1996006946A1 (fr) | 1994-08-26 | 1995-08-25 | Biocapteur et procede destines a la detection par luminescence electrophotochimique d'acides nucleiques adsorbes sur une surface solide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH10509025A true JPH10509025A (ja) | 1998-09-08 |
Family
ID=23142843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8508822A Pending JPH10509025A (ja) | 1994-08-26 | 1995-08-25 | 固体表面に吸着された核酸の電気的に発生した化学ルミネッセンス性検出のためのバイオセンサーおよび方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0777741A4 (fr) |
| JP (1) | JPH10509025A (fr) |
| AU (1) | AU703344B2 (fr) |
| CA (1) | CA2198489A1 (fr) |
| WO (1) | WO1996006946A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006075497A1 (fr) * | 2004-12-21 | 2006-07-20 | Kyoto University | Sonde, dispositif d'identification de region nucleotidique et procede d'identification de region nucleotidique |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786141A (en) * | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| CZ299135B6 (cs) * | 1995-03-10 | 2008-04-30 | Meso Scale Technologies, Llc. Corporation Servicecompany | Kazeta a zarízení pro použití pri detekci analytu, zpusob provádení testu za použití uvedené kazety, kit pro použití pri provádení množiny elektrochemiluminescencních testu a zpusob detekce nebo merení analytu |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| FR2762013B1 (fr) * | 1997-04-09 | 1999-06-04 | Cis Bio Int | Systemes de detection d'hybridation d'acides nucleiques, leur procede de preparation et leurs utilisations |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| CA2380258C (fr) | 1999-07-26 | 2008-07-15 | Clinical Micro Sensors, Inc. | Determination de sequences d'acides nucleiques par detection electronique |
| US6518024B2 (en) | 1999-12-13 | 2003-02-11 | Motorola, Inc. | Electrochemical detection of single base extension |
| EP1238114A2 (fr) * | 1999-12-09 | 2002-09-11 | Motorola, Inc. | Procedes et compositions se rapportant a la detection electrique des reactions d'acides nucleiques |
| US6824669B1 (en) | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
| US6706479B2 (en) * | 2000-10-05 | 2004-03-16 | Virginia Tech Intellectual Properties, Inc. | Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips |
| WO2005016115A2 (fr) | 2003-01-23 | 2005-02-24 | Montana State University | Biocapteurs faisant intervenir des ligands immobilises sur des dendrimeres et utilisation de ceux-ci |
| US7741033B2 (en) * | 2003-05-13 | 2010-06-22 | Trustees Of Boston College | Electrocatalytic nucleic acid hybridization detection |
| EP1629122B1 (fr) | 2003-05-13 | 2009-10-14 | The Trustees of Boston College | Detection electrocatalytique de l'hybridation d'acides nucleiques |
| CA2735735C (fr) | 2008-09-02 | 2016-11-22 | The Governing Council Of The University Of Toronto | Microelectrodes nanostructurees et dispositifs de biodetection les comprenant |
| JP5989668B2 (ja) | 2011-01-11 | 2016-09-07 | ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント | タンパク質検出方法 |
| EP2683822B1 (fr) | 2011-03-10 | 2020-04-22 | General Atomics | Dispositifs et méthodes de diagnostic et de préparation d'échantillons |
| CN117491623A (zh) | 2015-08-20 | 2024-02-02 | 豪夫迈·罗氏有限公司 | 使用聚乙二醇化分析物特异性结合剂的基于颗粒的免疫测定法 |
| CN108780092A (zh) | 2016-03-07 | 2018-11-09 | 豪夫迈·罗氏有限公司 | 抗p53抗体的检测 |
| EP3577460B1 (fr) | 2017-02-02 | 2021-01-20 | Roche Diagnostics GmbH | Immunodosage utilisant au moins deux agents de liaison analyte-spécifiques pegylés. |
| EP3781600A1 (fr) | 2018-04-18 | 2021-02-24 | F. Hoffmann-La Roche AG | Nouveaux anticorps anti-thymidine kinase |
| EP3844503B1 (fr) | 2018-08-31 | 2024-05-29 | F. Hoffmann-La Roche AG | Thymidine kinase (tk-1) dans la détermination d'indices de pronostic pour le dlbcl |
| BR112022000172A2 (pt) | 2019-07-22 | 2022-02-22 | Hoffmann La Roche | Métodos para avaliar se uma paciente tem endometriose, para selecionar uma paciente para terapia e para monitorar uma paciente |
| BR112022001140A2 (pt) | 2019-07-22 | 2022-03-15 | Hoffmann La Roche | Métodos para avaliar se um paciente tem endometriose ou está em risco de desenvolver endometriose, selecionar um paciente para terapia e monitorar um paciente que sofre de endometriose ou que está sendo tratado para endometriose |
| WO2021013786A1 (fr) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a6 en tant que biomarqueur du sang pour le diagnostic non invasif de l'endométriose |
| WO2021013781A1 (fr) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | Substance p en tant que biomarqueur du sang pour le diagnostic non invasif de l'endométriose |
| KR20220024782A (ko) | 2019-07-22 | 2022-03-03 | 에프. 호프만-라 로슈 아게 | 자궁내막증의 비침습적 진단을 위한 혈액 바이오마커로서의 s100a8 |
| JP2023502360A (ja) | 2019-11-15 | 2023-01-24 | エフ．ホフマン－ラ ロシュ アーゲー | 患者試料における質量分析測定のためのβ－ラクタム抗生物質の誘導体化 |
| CN111272742B (zh) * | 2020-03-06 | 2022-11-08 | 安徽大学 | 基于金属有机凝胶复合材料和金属有机框架的电致化学发光传感器及其制备和检测方法 |
| US20230406909A1 (en) | 2020-11-02 | 2023-12-21 | Roche Diagnostics Operations, Inc. | Sars-cov-2 nucleocapsid antibodies |
| WO2022207628A1 (fr) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf comme biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
| EP4314838A1 (fr) | 2021-04-01 | 2024-02-07 | F. Hoffmann-La Roche AG | Psp94 utilisée en tant que biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
| EP4341700A1 (fr) | 2021-05-17 | 2024-03-27 | F. Hoffmann-La Roche AG | Sfrp4 en tant que biomarqueur sanguin pour le diagnostic non invasif de l'adénomyose |
| CN118434762A (zh) | 2021-10-26 | 2024-08-02 | 豪夫迈·罗氏有限公司 | 对SARS-CoV-2 RBD具有特异性的单克隆抗体 |
| WO2023131594A1 (fr) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Dérivatisation de composés dans des échantillons de patients pour la pharmacovigilance thérapeutique (tdm) |
| WO2023247752A1 (fr) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Procédé de diagnostic de l'endométriose et de classification du stade de l'endométriose |
| WO2024017982A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriène a4 hydrolase (lta4h) en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques |
| WO2024017983A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Protéine de type météorine (metrnl) utilisée en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques |
| WO2024017985A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Protéine 1 de liaison au facteur de croissance des fibroblastes (fgfbp1) utilisée en tant que biomarqueur (sanguin) pour le diagnostic du syndrome des ovaires polykystiques |
| CN115414930B (zh) * | 2022-08-26 | 2023-10-31 | 重庆医科大学 | Ru(bpy)32+阳极或阴极共反应物及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1258580A (fr) * | 1967-12-28 | 1971-12-30 | ||
| US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5124022A (en) * | 1989-08-23 | 1992-06-23 | Aluminum Company Of America | Electrolytic capacitor and method of making same |
| US5019343A (en) * | 1989-12-15 | 1991-05-28 | W. R. Grace & Co.-Conn. | Control of corrosion in aqueous systems using certain phosphonomethyl amines |
| US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
-
1995
- 1995-08-25 AU AU34103/95A patent/AU703344B2/en not_active Ceased
- 1995-08-25 JP JP8508822A patent/JPH10509025A/ja active Pending
- 1995-08-25 CA CA002198489A patent/CA2198489A1/fr not_active Abandoned
- 1995-08-25 WO PCT/US1995/010630 patent/WO1996006946A1/fr not_active Application Discontinuation
- 1995-08-25 EP EP95930881A patent/EP0777741A4/fr not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006075497A1 (fr) * | 2004-12-21 | 2006-07-20 | Kyoto University | Sonde, dispositif d'identification de region nucleotidique et procede d'identification de region nucleotidique |
Also Published As
| Publication number | Publication date |
|---|---|
| AU703344B2 (en) | 1999-03-25 |
| EP0777741A1 (fr) | 1997-06-11 |
| WO1996006946A1 (fr) | 1996-03-07 |
| CA2198489A1 (fr) | 1996-03-07 |
| EP0777741A4 (fr) | 1999-01-13 |
| AU3410395A (en) | 1996-03-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH10509025A (ja) | 固体表面に吸着された核酸の電気的に発生した化学ルミネッセンス性検出のためのバイオセンサーおよび方法 | |
| Xu et al. | Immobilization and hybridization of DNA on an aluminum (III) alkanebisphosphonate thin film with electrogenerated chemiluminescent detection | |
| US6127127A (en) | Monolayer and electrode for detecting a label-bearing target and method of use thereof | |
| JP4618886B2 (ja) | サンプル中の標的の検出 | |
| US6096500A (en) | Multi-label complex for enhanced sensitivity in electrochemiluminescence assay | |
| Hendji et al. | Sensitive detection of pesticides using a differential ISFET-based system with immobilized cholinesterases | |
| Rai et al. | Electrochemical nanoporous alumina membrane-based label-free DNA biosensor for the detection of Legionella sp | |
| Dharuman et al. | Label-free impedance detection of oligonucleotide hybridisation on interdigitated ultramicroelectrodes using electrochemical redox probes | |
| IE69371B1 (en) | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets | |
| US20090036315A1 (en) | Device and methods for detecting and quantifying one or more target agents | |
| US9068979B2 (en) | Micro bio sensor and method for manufacturing the micro bio sensor | |
| US6387625B1 (en) | Monolayer and electrode for detecting a label-bearing target and method of use thereof | |
| Rasheed et al. | Quartz crystal microbalance genosensor for sequence specific detection of attomolar DNA targets | |
| Rasheed et al. | Femtomolar level detection of BRCA1 gene using a gold nanoparticle labeled sandwich type DNA sensor | |
| JP2004132954A (ja) | 一個または複数個の分析物を検出するための方法および装置、ならびに装置の使用 | |
| Truong et al. | Development of label-free impedimetric Hcg-immunosensor using screen-printed electrode | |
| Wang et al. | Coupling of background reduction with rolling circle amplification for highly sensitive protein detection via terminal protection of small molecule-linked DNA | |
| Cha et al. | Quantitative analysis of H5N1 DNA hybridization on nanowell array electrode | |
| US20100279278A1 (en) | Methods of detecting one or more bioterrorism target agents | |
| Miao et al. | Fabrication of multi-functionalized gold nanoparticles and the application to electrochemical detection of nitrite | |
| CN110849958B (zh) | 一种利用ZnO纳米棒提升光寻址电位传感器检测DNA性能的装置及方法 | |
| Wei et al. | Determination of surface-immobilized double-stranded DNA using a metallointercalator and catalytic voltammetry | |
| CN109856210B (zh) | 一种检测早期肺癌标记物nap-2蛋白的电化学发光生物传感器及其制备方法 | |
| Palchetti et al. | Electrochemical adsorption technique for immobilization of single-stranded oligonucleotides onto carbon screen-printed electrodes | |
| AU3676799A (en) | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to solid surface |