EP0773716A4 - Behandlung von lösungen roter blutkörperchen mit antivralen wirkstoffen - Google Patents

Behandlung von lösungen roter blutkörperchen mit antivralen wirkstoffen

Info

Publication number
EP0773716A4
EP0773716A4 EP96918369A EP96918369A EP0773716A4 EP 0773716 A4 EP0773716 A4 EP 0773716A4 EP 96918369 A EP96918369 A EP 96918369A EP 96918369 A EP96918369 A EP 96918369A EP 0773716 A4 EP0773716 A4 EP 0773716A4
Authority
EP
European Patent Office
Prior art keywords
red blood
blood cell
viral agents
cell solutions
treating red
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96918369A
Other languages
English (en)
French (fr)
Other versions
EP0773716A1 (de
Inventor
David Cook
Susan Wollowitz
Aileen Nerio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cerus Corp
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/476,842 external-priority patent/US6143490A/en
Application filed by Cerus Corp filed Critical Cerus Corp
Publication of EP0773716A1 publication Critical patent/EP0773716A1/de
Publication of EP0773716A4 publication Critical patent/EP0773716A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088Liquid substances
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/18011Details ssRNA Bacteriophages positive-sense
    • C12N2795/18111Leviviridae
    • C12N2795/18161Methods of inactivation or attenuation
    • C12N2795/18163Methods of inactivation or attenuation by chemical treatment
EP96918369A 1995-06-07 1996-06-07 Behandlung von lösungen roter blutkörperchen mit antivralen wirkstoffen Withdrawn EP0773716A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/476,842 US6143490A (en) 1994-11-14 1995-06-07 Treating blood or blood product with a compound having a mustard and a nucleic acid binding moiety
US476842 1995-06-07
US08/486,821 US6171777B1 (en) 1994-11-14 1995-06-07 Treating blood or blood product with a compound having a mustard and a nucleic acid binding moiety
US486821 1995-06-07
PCT/US1996/009616 WO1996039818A1 (en) 1995-06-07 1996-06-07 Treating red blood cell solutions with anti-viral agents

Publications (2)

Publication Number Publication Date
EP0773716A1 EP0773716A1 (de) 1997-05-21
EP0773716A4 true EP0773716A4 (de) 1999-08-04

Family

ID=27045311

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96918369A Withdrawn EP0773716A4 (de) 1995-06-07 1996-06-07 Behandlung von lösungen roter blutkörperchen mit antivralen wirkstoffen

Country Status (4)

Country Link
EP (1) EP0773716A4 (de)
AU (1) AU722811B2 (de)
CA (1) CA2199731A1 (de)
WO (1) WO1996039818A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691132A (en) 1994-11-14 1997-11-25 Cerus Corporation Method for inactivating pathogens in red cell compositions using quinacrine mustard
US6177441B1 (en) 1995-06-05 2001-01-23 Cerus Corporation Treating red blood cell solutions with anti-viral agents
US6114108A (en) * 1995-08-29 2000-09-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of viral nucleic acids
US6136586A (en) * 1995-08-29 2000-10-24 Vi Technologies, Inc. Methods for the selective modification of viral nucleic acids
US6093725A (en) * 1997-01-06 2000-07-25 Cerus Corporation Frangible compounds for pathogen inactivation
DE69827770T2 (de) * 1997-01-06 2006-03-02 Cerus Corp., Concord Adsorbentien und geräte zur verminderung von kleinen organischen verbindungen aus blutprodukten
US6514987B1 (en) 1997-01-06 2003-02-04 Cerus Corporation Frangible compounds for pathogen inactivation
CN101676268B (zh) * 1997-01-06 2013-09-25 塞鲁斯公司 用于病原体灭活的脆性化合物
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
EP1364944A1 (de) * 1997-01-06 2003-11-26 Cerus Corporation Verbindungen mit leicht spaltbaren Bindungen zur Inaktivierung von Pathogenen
AU773836B2 (en) * 1997-01-06 2004-06-10 Cerus Corporation Methods and devices for the reduction of small organic compounds from blood products
US5891705A (en) * 1997-04-08 1999-04-06 Pentose Pharmaceuticals, Inc. Method for inactivating a virus
US6093564A (en) * 1997-10-03 2000-07-25 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids
US6352695B1 (en) 1997-10-03 2002-03-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids
AU759966C (en) * 1998-01-06 2004-02-12 Cerus Corporation Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
WO1999034839A1 (en) 1998-01-06 1999-07-15 Cerus Corporation Methods for quenching pathogen inactivators in biological materials
US6369048B1 (en) 1998-01-12 2002-04-09 V.I. Technologies, Inc. Methods and compositions for inactivating viruses
EP1085880A2 (de) 1998-06-11 2001-03-28 Cerus Corporation Verwendung von alkylierungsmitteln zur hemmung der proliferation von glatten muskelzellen
US6403359B1 (en) 1998-09-25 2002-06-11 V. I. TECHNOLOGIES, Inc. Solid phase quenching systems
US6617100B2 (en) 1998-09-25 2003-09-09 V.I. Technologies, Inc. Solid phase quenching systems
US6150109A (en) 1999-01-25 2000-11-21 V. I. TECHNOLOGIES, Inc. Lipophilic quenching of viral inactivating agents
DE10051628B4 (de) * 2000-10-18 2007-06-06 Fresenius Hemocare Beteiligungs Gmbh Einzelsträngiges Oligonukleotid und dessen Verwendung
US20020131958A1 (en) * 2001-01-22 2002-09-19 John Chapman Method for purifying a biological composition
AU2004224425B2 (en) 2003-02-06 2010-06-24 Aduro Biotech Modified free-living microbes, vaccine compositions and methods of use thereof
CA2515369C (en) 2003-02-06 2015-03-31 Cerus Corporation Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the listeria, and methods of use thereof
US7695725B2 (en) 2003-02-06 2010-04-13 Aduro Biotech Modified free-living microbes, vaccine compositions and methods of use thereof
JP2007512341A (ja) * 2003-11-21 2007-05-17 メルク エンド カムパニー インコーポレーテッド 神経障害性疼痛の治療に有用なピリジン−4−イルアミン化合物
CN103961731B (zh) 2004-10-29 2017-01-18 塞鲁斯公司 用于红细胞灭活过程的改进的猝灭方法
CN102046006B (zh) 2008-04-09 2014-09-24 塞鲁斯公司 用于红细胞病原体灭活的改进猝灭方法
CN101857598B (zh) * 2010-06-25 2012-11-28 西安交通大学 一种具有降高血压活性的呋喃香豆素类化合物及其制备方法
WO2012154879A2 (en) 2011-05-09 2012-11-15 Van Andel Research Institute Autophagy inhibitors
EP3313418B1 (de) 2015-06-26 2024-03-13 Cerus Corporation Kryopräzipitatzusammensetzungen und verfahren zur herstellung davon
EP3364986B1 (de) 2015-10-23 2023-12-13 Cerus Corporation Pathogen-inaktiviertes kryoarmes plasma und verfahren zur verwendung davon
US11235090B2 (en) 2017-03-03 2022-02-01 Cerus Corporation Kits and methods for preparing pathogen-inactivated platelet compositions
CN116571191A (zh) 2017-12-29 2023-08-11 塞鲁斯公司 用于处理生物流体的系统和方法
CA3143732A1 (en) 2019-06-28 2020-12-30 Cerus Corporation System and methods for implementing a biological fluid treatment device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111418A2 (de) * 1982-12-08 1984-06-20 Edelson, Richard L., Dr. System zur Blutbehandlung ausserhalb des Körpers
US5342752A (en) * 1990-04-16 1994-08-30 Cryopharm Corporation Method of inactivation of viral blood contaminants using acridine deriatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182750A (en) * 1977-04-21 1980-01-08 Sullivan Thomas E Bloodcompatible functional polymers
US5593823A (en) * 1993-06-28 1997-01-14 Cerus Corporation Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens
US5399719A (en) * 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
WO1996040857A1 (en) * 1995-06-07 1996-12-19 Cerus Corporation Methods and devices for the removal of psoralens from blood products

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111418A2 (de) * 1982-12-08 1984-06-20 Edelson, Richard L., Dr. System zur Blutbehandlung ausserhalb des Körpers
US5342752A (en) * 1990-04-16 1994-08-30 Cryopharm Corporation Method of inactivation of viral blood contaminants using acridine deriatives

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
RYTIR V ET AL: "Effect of certain compounds during elimination of plasmids in Escherichia coli", FOLIA MICROBIOLOGICA, vol. 20, no. 1, 1975, Prague, Czech., pages 17 - 23, XP002101363 *
See also references of WO9639818A1 *

Also Published As

Publication number Publication date
EP0773716A1 (de) 1997-05-21
AU722811B2 (en) 2000-08-10
AU6104996A (en) 1996-12-30
CA2199731A1 (en) 1996-12-19
WO1996039818A1 (en) 1996-12-19

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