EP0722326A4 - Maltooligosaccharides fortement sulfatees presentant des proprietes semblables a l'heparine - Google Patents

Maltooligosaccharides fortement sulfatees presentant des proprietes semblables a l'heparine

Info

Publication number
EP0722326A4
EP0722326A4 EP94931314A EP94931314A EP0722326A4 EP 0722326 A4 EP0722326 A4 EP 0722326A4 EP 94931314 A EP94931314 A EP 94931314A EP 94931314 A EP94931314 A EP 94931314A EP 0722326 A4 EP0722326 A4 EP 0722326A4
Authority
EP
European Patent Office
Prior art keywords
heparin
properties
highly sulfated
maltooligosaccharides
sulfated maltooligosaccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94931314A
Other languages
German (de)
English (en)
Other versions
EP0722326A1 (fr
Inventor
Peter Fugedi
David John Tyrrell
Robert James Tressler
Robert Joseph Stack
Masayuki Ishihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycomed Inc
Original Assignee
Glycomed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomed Inc filed Critical Glycomed Inc
Publication of EP0722326A1 publication Critical patent/EP0722326A1/fr
Publication of EP0722326A4 publication Critical patent/EP0722326A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
EP94931314A 1993-10-07 1994-10-04 Maltooligosaccharides fortement sulfatees presentant des proprietes semblables a l'heparine Withdrawn EP0722326A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13348393A 1993-10-07 1993-10-07
US133483 1993-10-07
PCT/US1994/011368 WO1995009637A1 (fr) 1993-10-07 1994-10-04 Maltooligosaccharides fortement sulfatees presentant des proprietes semblables a l'heparine

Publications (2)

Publication Number Publication Date
EP0722326A1 EP0722326A1 (fr) 1996-07-24
EP0722326A4 true EP0722326A4 (fr) 1999-10-06

Family

ID=22458825

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94931314A Withdrawn EP0722326A4 (fr) 1993-10-07 1994-10-04 Maltooligosaccharides fortement sulfatees presentant des proprietes semblables a l'heparine

Country Status (5)

Country Link
EP (1) EP0722326A4 (fr)
JP (1) JPH09503510A (fr)
AU (1) AU700451B2 (fr)
CA (1) CA2171465A1 (fr)
WO (1) WO1995009637A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN261895A0 (en) * 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
AUPO888497A0 (en) * 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
DE19747195A1 (de) * 1997-10-24 1999-04-29 Knoll Ag Verwendung von Glykosaminoglykanen zur Herstellung von pharmazeutischen Zubereitungen zur Behandlung von mit Diabetes assoziierten Augenkrankheiten
AU3837300A (en) * 1999-04-15 2000-11-02 Takara Shuzo Co., Ltd. Remedies
US6608042B2 (en) * 2000-03-28 2003-08-19 Aventis Pharma, S.A. Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof
ATE511846T1 (de) 2001-09-12 2011-06-15 Sigma Tau Res Switzerland Sa Derivate von teildesulfatierten glycosaminoglycanen als inhibitoren von heparanase, mit antiangiogener wirkung und ohne antikoagulatorische wirkung
ES2531880T3 (es) * 2004-03-04 2015-03-20 Progen Pharmaceuticals Limited Derivados de oligosacáridos sulfatados
CN100363373C (zh) * 2005-01-14 2008-01-23 庄茅 异麦芽低聚糖硫酸酯（imos）的制备方法
RU2483074C2 (ru) * 2007-10-16 2013-05-27 Проджен Фармасьютикалз Лимитед Новые сульфатированные производные олигосахаридов
EP2809326B1 (fr) * 2012-01-30 2018-07-25 Baxalta GmbH Polysaccharides sulfatés ou sulfonés non anticoagulants
EP2832848B1 (fr) 2012-03-30 2019-02-13 Ajinomoto Co., Inc. Milieu de culture pour faire proliférer une cellule souche, qui contient un composé sulfaté
US11718609B2 (en) 2016-12-13 2023-08-08 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108713A (en) * 1980-02-01 1981-08-28 Nippon Kayaku Co Ltd Antitumor preparation
JPH03145496A (ja) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc オリゴ糖誘導体
EP0479093A1 (fr) * 1990-10-03 1992-04-08 F. Hoffmann-La Roche Ag Dérivés oligosaccharides et leurs utilisations comme médicaments

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066829A (en) * 1976-07-12 1978-01-03 American Cyanamid Company Malto-dextrin poly(H-)sulfates
US4021544A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
US4435387A (en) * 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
JPS5951583A (ja) * 1983-06-15 1984-03-26 Nippon Telegr & Teleph Corp <Ntt> 半導体レ−ザ装置
US4470976A (en) * 1983-08-29 1984-09-11 American Cyanamid Company Poly-cation salt of 4-O-polyhexaose-thio-arylene sulfates
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
WO1989003684A1 (fr) * 1987-10-30 1989-05-05 Chugai Seiyaku Kabushiki Kaisha Agent anti-vih
JPH036457A (ja) * 1989-06-02 1991-01-11 Koyo Seiko Co Ltd 車輪回転速度検出器を備えた車軸用軸受装置
JP2792914B2 (ja) * 1989-06-02 1998-09-03 光洋精工株式会社 車輪回転速度検出器を備えた車軸用軸受装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108713A (en) * 1980-02-01 1981-08-28 Nippon Kayaku Co Ltd Antitumor preparation
JPH03145496A (ja) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc オリゴ糖誘導体
EP0479093A1 (fr) * 1990-10-03 1992-04-08 F. Hoffmann-La Roche Ag Dérivés oligosaccharides et leurs utilisations comme médicaments

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 15, no. 361 (C - 867) 12 September 1991 (1991-09-12) *
PATENT ABSTRACTS OF JAPAN vol. 5, no. 184 (C - 80) 21 November 1981 (1981-11-21) *
See also references of WO9509637A1 *

Also Published As

Publication number Publication date
EP0722326A1 (fr) 1996-07-24
JPH09503510A (ja) 1997-04-08
AU700451B2 (en) 1999-01-07
WO1995009637A1 (fr) 1995-04-13
AU8013694A (en) 1995-05-01
CA2171465A1 (fr) 1995-04-13

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