EP0671941A4 - Bradykininantagonisten. - Google Patents

Bradykininantagonisten.

Info

Publication number
EP0671941A4
EP0671941A4 EP93924412A EP93924412A EP0671941A4 EP 0671941 A4 EP0671941 A4 EP 0671941A4 EP 93924412 A EP93924412 A EP 93924412A EP 93924412 A EP93924412 A EP 93924412A EP 0671941 A4 EP0671941 A4 EP 0671941A4
Authority
EP
European Patent Office
Prior art keywords
bradykinin antagonists
bradykinin
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93924412A
Other languages
English (en)
French (fr)
Other versions
EP0671941A1 (de
Inventor
John C Chronis
James K Blodgett
Val Smith Goodfellow
Manoj V Marathe
Lyle W Spruce
Eric T Whalley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortech Inc
Original Assignee
Cortech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortech Inc filed Critical Cortech Inc
Publication of EP0671941A1 publication Critical patent/EP0671941A1/de
Publication of EP0671941A4 publication Critical patent/EP0671941A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP93924412A 1992-11-10 1993-10-29 Bradykininantagonisten. Withdrawn EP0671941A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97400092A 1992-11-10 1992-11-10
US974000 1992-11-10
PCT/US1993/010222 WO1994011021A1 (en) 1992-11-10 1993-10-29 Bradykinin antagonists

Publications (2)

Publication Number Publication Date
EP0671941A1 EP0671941A1 (de) 1995-09-20
EP0671941A4 true EP0671941A4 (de) 1996-05-29

Family

ID=25521455

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93924412A Withdrawn EP0671941A4 (de) 1992-11-10 1993-10-29 Bradykininantagonisten.

Country Status (11)

Country Link
EP (1) EP0671941A4 (de)
JP (1) JPH08503460A (de)
CN (1) CN1094058A (de)
AU (1) AU5410994A (de)
CA (1) CA2147869A1 (de)
IL (1) IL107400A0 (de)
MX (1) MX9306988A (de)
NZ (1) NZ257477A (de)
PL (1) PL304654A1 (de)
WO (1) WO1994011021A1 (de)
ZA (1) ZA938014B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003308A1 (en) * 1993-07-23 1995-02-02 Toray Industries, Inc. Morphinan derivative and medicinal use
AU6044496A (en) * 1995-06-05 1996-12-24 Cortech, Inc. Compounds having bradykinin antagonistic activity and mu-opi oid agonistic activity
DE69627191T2 (de) * 1995-06-09 2004-01-08 The Regents Of The University Of Michigan, Ann Arbor Bradikininanaloge als selektive thrombininhibitoren
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
DE19642289A1 (de) 1996-10-14 1998-04-16 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit
US6982249B1 (en) 1997-04-23 2006-01-03 The Regents Of The University Of Michigan Bradykinin analogs as selective inhibitors of cell activation
US6359111B1 (en) * 1998-05-28 2002-03-19 Neorx Corporation Opioid receptor targeting
US6716452B1 (en) 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US7060708B2 (en) 1999-03-10 2006-06-13 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
EP2080511A3 (de) * 2000-08-22 2009-09-30 Shire LLC Aktivmittelzufuhrsysteme und Verfahren zum Schutz und zur Lieferung von Aktivmitteln
WO2003020200A2 (en) 2000-11-16 2003-03-13 New River Pharmaceuticals Inc. A novel pharmaceutical compound and methods of making and using same
EP1357928B1 (de) * 2000-11-16 2011-11-16 Shire LLC Neuartige pharmazeutische verbindung und verfahren zur herstellung und verwendung derselben
AU2001297565B2 (en) * 2000-11-16 2008-06-05 Takeda Pharmaceutical Company Limited A novel pharmaceutical compound and methods of making and using same
US7169752B2 (en) 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
US7375082B2 (en) 2002-02-22 2008-05-20 Shire Llc Abuse-resistant hydrocodone compounds
US7338939B2 (en) 2003-09-30 2008-03-04 New River Pharmaceuticals Inc. Abuse-resistant hydrocodone compounds
WO2003072046A2 (en) 2002-02-22 2003-09-04 New River Pharmaceuticals Inc. Novel sustained release pharmaceutical compounds to prevent abuse of controlled substances
US7700561B2 (en) 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs
AR040956A1 (es) 2002-07-31 2005-04-27 Schering Ag Nuevos conjugados de efectores, procedimientos para su preparacion y su uso farmaceutico
JP2006505627A (ja) * 2002-07-31 2006-02-16 シエーリング アクチエンゲゼルシャフト 新規エフェクター接合体、それらの生成方法及びそれらの医薬使用
EA008864B1 (ru) 2003-09-30 2007-08-31 Нью Ривер Фармасьютикалз Инк. Фармацевтические композиции для предотвращения передозировки или неправильного употребления лекарственных средств
GB0624880D0 (en) * 2006-12-14 2007-01-24 Johnson Matthey Plc Improved method for making analgesics

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017201A1 (en) * 1991-04-01 1992-10-15 Cortech, Inc. Bradykinin antagonists
EP0514361A1 (de) * 1991-05-15 1992-11-19 Aktiebolaget Astra Galanin-Antagonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894443A (en) * 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017201A1 (en) * 1991-04-01 1992-10-15 Cortech, Inc. Bradykinin antagonists
EP0514361A1 (de) * 1991-05-15 1992-11-19 Aktiebolaget Astra Galanin-Antagonist

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
12th American Peptide Symposium, Cambridge, June 16-21, 1991; Program and Abstracts *
J.C. CHERONIS ET AL.: "A New Class of Bradykinin Antagonists: Synthesis and in Vitro Activity of Bissuccinimidoalkane Peptide Dimers", JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, no. 9, 1 May 1992 (1992-05-01), WASHINGTON US, pages 1563 - 1572, XP002246182, DOI: doi:10.1021/jm00087a010 *
See also references of WO9411021A1 *

Also Published As

Publication number Publication date
PL304654A1 (en) 1995-01-09
CN1094058A (zh) 1994-10-26
MX9306988A (es) 1995-01-31
ZA938014B (en) 1994-07-11
JPH08503460A (ja) 1996-04-16
CA2147869A1 (en) 1994-05-26
NZ257477A (en) 1996-07-26
IL107400A0 (en) 1994-01-25
EP0671941A1 (de) 1995-09-20
WO1994011021A1 (en) 1994-05-26
AU5410994A (en) 1994-06-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950520

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RHK1 Main classification (correction)

Ipc: C07K 7/18

A4 Supplementary search report drawn up and despatched
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18W Application withdrawn

Withdrawal date: 19971015