EP0663925A4 - Aminosäure-mimetika als elutionsreagentien in affinitätsreinigungsmethoden. - Google Patents

Aminosäure-mimetika als elutionsreagentien in affinitätsreinigungsmethoden.

Info

Publication number
EP0663925A4
EP0663925A4 EP93923139A EP93923139A EP0663925A4 EP 0663925 A4 EP0663925 A4 EP 0663925A4 EP 93923139 A EP93923139 A EP 93923139A EP 93923139 A EP93923139 A EP 93923139A EP 0663925 A4 EP0663925 A4 EP 0663925A4
Authority
EP
European Patent Office
Prior art keywords
protein
molecule
complex
amino acid
elution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93923139A
Other languages
English (en)
French (fr)
Other versions
EP0663925A1 (de
Inventor
Brian Seed
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of EP0663925A1 publication Critical patent/EP0663925A1/de
Publication of EP0663925A4 publication Critical patent/EP0663925A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
EP93923139A 1992-10-02 1993-09-27 Aminosäure-mimetika als elutionsreagentien in affinitätsreinigungsmethoden. Withdrawn EP0663925A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95666092A 1992-10-02 1992-10-02
US956660 1992-10-02
PCT/US1993/009174 WO1994007912A1 (en) 1992-10-02 1993-09-27 Affinity purification methods involving amino acid mimetics as elution reagents

Publications (2)

Publication Number Publication Date
EP0663925A1 EP0663925A1 (de) 1995-07-26
EP0663925A4 true EP0663925A4 (de) 1997-11-19

Family

ID=25498506

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93923139A Withdrawn EP0663925A4 (de) 1992-10-02 1993-09-27 Aminosäure-mimetika als elutionsreagentien in affinitätsreinigungsmethoden.

Country Status (6)

Country Link
EP (1) EP0663925A4 (de)
JP (1) JPH08503698A (de)
AU (1) AU5292693A (de)
CA (1) CA2146162A1 (de)
MX (1) MX9306174A (de)
WO (1) WO1994007912A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1864999T3 (da) * 1996-11-27 2009-06-29 Genentech Inc Affinitetsoprensning af polypeptid på protein A-matrix
WO2001069258A1 (en) * 2000-03-16 2001-09-20 Biacore Ab Method for capturing analytes eluted from surface-bound ligands
US8084032B2 (en) 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
RU2012151132A (ru) 2010-05-19 2014-06-27 Ф. Хоффманн-Ля Рош Аг Хроматография с гиброфобным взаимодействием
JP6236948B2 (ja) * 2013-07-17 2017-11-29 東ソー株式会社 抗体精製用溶出液および当該溶出液を用いた抗体精製方法
HRP20160086A2 (hr) 2016-01-27 2017-08-11 Sveučilište u Zagrebu Eluens za imunoafinitetnu kromatografiju virusa i proteina

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 107, no. 17, 26 October 1987, Columbus, Ohio, US; abstract no. 150534, XP002040255 *
CHEMICAL ABSTRACTS, vol. 108, no. 11, 14 March 1988, Columbus, Ohio, US; abstract no. 91168, XP002040254 *
CHEMICAL ABSTRACTS, vol. 112, no. 15, 9 April 1990, Columbus, Ohio, US; abstract no. 135398, XP002040253 *
E SULKOWSKI: "Immobilized metal ion affinity chromatography of proteins", UCLA SYMP. MOL. CELL. BIOL., NEW SER., vol. 68, 1987, pages 149 - 162 *
M BELEW & J PORATH: "Immobilized metal ion affinity chromatography. Effect of solute structure, ligand density and salt concnetation on the retention of peptides", JOURNAL OF CHROMATOGRAPHY, vol. 516, 1990, AMSTERDAM NL, pages 333 - 354, XP002040252 *
M BELEW ET AL.: "High-performance analytical applications of immobilized metal ion affinity chromatography", ANALYTICAL BIOCHEMISTRY, vol. 164, no. 2, 1987, NEW YORK US, pages 457 - 465, XP024816831, DOI: doi:10.1016/0003-2697(87)90519-7 *
M KASTNER & D NEUBERT: "Highperformance metal chelate affinity chromatography of cytochromes P-450 using Chelating Superose", JOURNAL OF CHROMATOGRAPHY, vol. 587, 1991, AMSTERDAM NL, pages 43 - 54, XP002040251 *
See also references of WO9407912A1 *
T T YIP ET AL.: "Evaluation of the interaction of peptides with copper (II), nickel (II), and zinc (II), by high-performance immobilized metal ion affinity", ANALYTICAL BIOCHEMISTRY, vol. 183, no. 1, 1989, NEW YORK US, pages 159 - 171 *
Y NAKAGAWA ET AL.: "High-performance immobilized metal ion affinity chromatography of peptides; analytical separation of biologically active synthetic peptides", ANALYTICAL BIOCHEMISTRY, vol. 168, 1988, NEW YORK US, pages 75 - 81, XP002040250 *

Also Published As

Publication number Publication date
JPH08503698A (ja) 1996-04-23
EP0663925A1 (de) 1995-07-26
CA2146162A1 (en) 1994-04-14
AU5292693A (en) 1994-04-26
MX9306174A (es) 1995-01-31
WO1994007912A1 (en) 1994-04-14

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