EP0539491A4 - - Google Patents

Info

Publication number
EP0539491A4
EP0539491A4 EP19910913697 EP91913697A EP0539491A4 EP 0539491 A4 EP0539491 A4 EP 0539491A4 EP 19910913697 EP19910913697 EP 19910913697 EP 91913697 A EP91913697 A EP 91913697A EP 0539491 A4 EP0539491 A4 EP 0539491A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910913697
Other versions
EP0539491A1 (en
Inventor
Fred A. Cohen
Robert A. Nissenson
Gordon J. Strewler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of EP0539491A1 publication Critical patent/EP0539491A1/en
Publication of EP0539491A4 publication Critical patent/EP0539491A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP91913697A 1990-07-13 1991-07-15 PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 Withdrawn EP0539491A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55376090A 1990-07-13 1990-07-13
US553760 1990-07-13

Publications (2)

Publication Number Publication Date
EP0539491A1 EP0539491A1 (en) 1993-05-05
EP0539491A4 true EP0539491A4 (show.php) 1994-03-23

Family

ID=24210645

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91913697A Withdrawn EP0539491A1 (en) 1990-07-13 1991-07-15 PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9

Country Status (5)

Country Link
EP (1) EP0539491A1 (show.php)
JP (1) JPH05509098A (show.php)
AU (1) AU667662B2 (show.php)
CA (1) CA2087190A1 (show.php)
WO (1) WO1992000753A1 (show.php)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5434246A (en) * 1992-03-19 1995-07-18 Takeda Chemical Industries, Ltd. Parathyroid hormone derivatives
US5814603A (en) * 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5977070A (en) * 1992-07-14 1999-11-02 Piazza; Christin Teresa Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
US6235288B1 (en) 1992-08-26 2001-05-22 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
JP3754072B2 (ja) * 1994-03-22 2006-03-08 リサーチ・コーポレーション・テクノロジーズ・インコーポレーテッド 摂食抑制ペプチド
CO4410206A1 (es) * 1994-07-28 1997-01-09 Sandoz Ag DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
US6117455A (en) 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use
EP0878201B1 (en) * 1996-02-01 2002-06-19 Chugai Seiyaku Kabushiki Kaisha Medicaments for the treatment or prevention of thrombocytopenia
CN1095681C (zh) * 1996-06-20 2002-12-11 久光制药株式会社 一种用于离子电渗疗法的装置结构
TW505654B (en) * 1996-07-30 2002-10-11 Hoffmann La Roche Synthesis of analogs of PTH and PTHrP
CN1817906B (zh) * 1996-09-26 2011-08-10 中外制药株式会社 抗人副甲状腺激素相关蛋白的抗体
TR199900666T2 (xx) 1996-09-26 1999-06-21 Chugai Seiyaku Kabushiki Kaisha �nsan paratormonu ile ilgili peptidlere kar�� antikor.
EP1004313B1 (en) * 1997-05-15 2007-05-02 Chugai Seiyaku Kabushiki Kaisha Cachexia remedy
KR20010083069A (ko) * 1998-06-26 2001-08-31 나가야마 오사무 고칼슘혈증치료제
TWI255718B (en) 1999-07-02 2006-06-01 Chugai Pharmaceutical Co Ltd Ameliorative agent for low vasopressin concentration
CA2373885A1 (en) * 1999-07-02 2001-01-11 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for diseases caused by pth or pthrp
WO2001002012A1 (fr) * 1999-07-06 2001-01-11 Chugai Seiyaku Kabushiki Kaisha Remedes contre l'hypercalcemie chimio-resistante
US20030049211A1 (en) * 2000-01-25 2003-03-13 Atsuhiko Kato Remedies and preventives for dental diseases
CA2401357A1 (en) * 2000-02-28 2001-09-07 Chugai Seiyaku Kabushiki Kaisha Tissue degradation inhibitor agent
US8029793B2 (en) 2000-04-28 2011-10-04 Chugai Seiyaku Kabushiki Kaisha Methods for inhibiting cell proliferation
CA2472472A1 (en) 2002-01-10 2003-07-24 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886132A (en) * 1972-12-21 1975-05-27 Us Health Human parathyroid hormone
US4508828A (en) * 1983-03-21 1985-04-02 Immuno Nuclear Corporation Bioassay of parathyroid hormone
US4771124A (en) * 1987-05-26 1988-09-13 Merck & Co., Inc. Parathyroid hormone antagonists with simplified synthetic methodology
US4968669A (en) * 1988-05-09 1990-11-06 Merck & Co., Inc. Parathyroid hormone antagonists

Also Published As

Publication number Publication date
AU8299091A (en) 1992-02-04
WO1992000753A1 (en) 1992-01-23
CA2087190A1 (en) 1992-01-14
JPH05509098A (ja) 1993-12-16
EP0539491A1 (en) 1993-05-05
AU667662B2 (en) 1996-04-04

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19930202

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19940202

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

RHK1 Main classification (correction)

Ipc: C07K 3/04

17Q First examination report despatched

Effective date: 19960819

GRAG Despatch of communication of intention to grant

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GRAH Despatch of communication of intention to grant a patent

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STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19980505