EP0434773A1 - Analysegerät - Google Patents

Analysegerät

Info

Publication number
EP0434773A1
EP0434773A1 EP19900904599 EP90904599A EP0434773A1 EP 0434773 A1 EP0434773 A1 EP 0434773A1 EP 19900904599 EP19900904599 EP 19900904599 EP 90904599 A EP90904599 A EP 90904599A EP 0434773 A1 EP0434773 A1 EP 0434773A1
Authority
EP
European Patent Office
Prior art keywords
sample
belt
analysis
measuring device
speed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900904599
Other languages
German (de)
English (en)
French (fr)
Inventor
Peter Dr. Med. Schulz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0434773A1 publication Critical patent/EP0434773A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/4875Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G01N33/48764Test tape taken off a spool
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00009Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with a sample supporting tape, e.g. with absorbent zones

Definitions

  • the invention relates to an analysis device for determining a parameter of a sample that can be applied to a reagent carrier and can be supplied to a measuring device, in particular liquid, with a transport device by means of which the reagent carrier carried by a band can be moved towards the measuring device by at least one sample supply.
  • DE-AS 16 73 340 describes an analyzing device for analyzing samples which are transferred from a movable sample carrier to an analysis band provided with a number of reagent positions, which is by means of a drive device at a transfer point and at an off. value device for evaluating at least one of the physical properties of the reaction mixture formed in each case is drawn in.
  • a transfer device provided with a dimensioning element, which transfers at least one dimensioned part of a sample from a sample memory, or at least one, directly to at least one reagent memory location.
  • the invention has for its object to further develop the generic device so that the samples can be properly evaluated regardless of the incubation times of the individual samples.
  • the section of the belt located between the sample supply and the measuring device is arranged in a container which is designed as an incubator and is dimensioned such that it depends on the sample volume and the incubation time on belt sections of different lengths Record length and thus absorb different speeds of different belt sections, the belt speed of the belt section evaluated by the measuring device being matched to the measuring speed of the measuring device and / or reaction speed on the reagent carrier, while the belt speed of the belt section working together with the sample supply is coordinated with the speed the sample supply is coordinated.
  • the invention is at least achieved when the analysis plates or reaction layers are on a relatively long, band-like, easily movable supports are arranged and can be transported from at least one sample feed to the measuring device by means of a transport device.
  • the actual throughput i.e. the number of samples evaluated depends essentially on two parameters: on the one hand on the measuring speed and on the other hand on the minimum time required for a reagent carrier to be able to react with the sample in such a way that the sample can be evaluated. Since the reaction rate depends, among other things, on time and temperature, it is advisable for the temperature in the incubator to be as constant as possible.
  • a particularly expedient embodiment provides that a supply module for the belt is connected upstream of the transport device.
  • the storage module is designed as a tape dispenser.
  • Such a storage module can have a band of several meters in length with a large number of analysis plates and contain a desiccator.
  • a further expedient embodiment of the invention provides that the container is followed by a collecting container designed as a waste collector.
  • a particularly expedient embodiment of the invention provides that several analysis devices are connected in parallel with one another to form an analysis system, each is provided, and in that the analysis system Zufuhi system samples cooperates with a, the sample delivery move transversely toaturs ⁇ * rect on of the bands.
  • a horizontally moving pipetting mechanism then applies successively to all stations with serum.
  • the entire system can be connected to an evaluation computer which not only controls the sample feed system, but also the transport of individual strips and enables the evaluation of the individual samples.
  • 1 is an analysis device with a transport device
  • Fig. 2 shows a portion of a tape with Ana lysep
  • Fig. 3 is an analysis system consisting of several analyzers.
  • FIG. 1 shows an analysis device for the photometric determination of a parameter of a sample 18 that can be applied to a reagent carrier 12 and determined by a measuring device 16 (cf. FIG. 2).
  • a transport device 20 is connected to the measuring and evaluation device 10, through which the reagent carriers 12 to 15 carried by a band can be moved from a sample feed 30 to the measuring device 16.
  • the section 32 of the band 22 located between the sample feed 30 and the measuring device 16 is arranged in a container 34, here an incubator. Section 32 forms a variable, loop hanging down.
  • the transport device 20 is designed such that the belt speed of the belt section 36 evaluated by the measuring device 16 is matched to the measuring speed of the measuring device 16, while the belt speed of the belt section 38 cooperating with the sample feed 30 is matched to the speed of the sample feed 30.
  • the loop 32 enables continuous operation of the measuring device 16 and the sample feed 30 because the different speeds of the belt sections 36 and 38 can be absorbed by them.
  • the distance between the measuring device 16 and the sample feed 30 is greater than the distance between two reagent carriers 12 and 13.
  • the transport device 20 is connected upstream of a supply module 21 for the belt 22.
  • the storage module 21 is designed as a tape dispenser.
  • the container 34 is followed by a collection container 40 designed as a waste collector.
  • the transport device is arranged in the container 34 and that the storage module 21, the container 34 and the collecting container 40 are designed as a modular system.
  • the sample feed 30 consists of a pipette needle 50 which is connected to a line 54 via a carrier 52.
  • the carrier 50 is actuated by a manipulator 56 which can move horizontally and transversely to the belt 22.
  • the storage container 21 has a slot 60 through which the band 22 is led out and transported under the pipette needle 50.
  • the storage container 21 is followed by the incubator 34, which also has a slot 62, on the inside of which two rollers 64 and 66 are stored and cooperate with the belt 22. These rollers 64 and 66 are controlled and move the belt 22 step by step, whenever an analysis plate 12 to 15 has been provided with a sample.
  • FIG. 3 an analysis system is shown which e.g. consists of new analysis devices 80 to 88, each of which is assigned a transport device 90 to 97.
  • This analysis system is controlled by a control unit 100.
  • the measured parameters can then be illustrated by a printer 101.
  • the analysis system consists of a primary sample module 120 with a sample room in which the samples 110, 111 and 112 are accommodated.
  • the sample is handled, for example, via a dilutor 102 and its line 54.
  • the manipulator 56 is designed such that the sample needle can be moved back and forth and vertically in the direction of the double arrow. With this arrangement, nine parameters of a sample can therefore be measured, the nine parameters being regarded as exemplary.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP19900904599 1989-03-13 1990-03-13 Analysegerät Withdrawn EP0434773A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3908123 1989-03-13
DE19893908123 DE3908123A1 (de) 1989-03-13 1989-03-13 Analysegeraet

Publications (1)

Publication Number Publication Date
EP0434773A1 true EP0434773A1 (de) 1991-07-03

Family

ID=6376233

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900904599 Withdrawn EP0434773A1 (de) 1989-03-13 1990-03-13 Analysegerät

Country Status (3)

Country Link
EP (1) EP0434773A1 (pt)
DE (1) DE3908123A1 (pt)
WO (1) WO1990010874A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4411661A1 (de) * 1994-04-05 1995-10-12 Schoettler Markus Dipl Geol Videotechnisches Multiparameter-Analyseverfahren
DE19819407A1 (de) * 1998-04-30 1999-11-11 Hendrik Priebs Teststreifenbehälter für Messgeräte, die mit Einwegteststreifen arbeiten
DE10105549A1 (de) 2001-02-06 2002-08-29 Roche Diagnostics Gmbh System zur Überwachung der Konzentration von Analyten in Körperflüssigkeiten
DE10233212B4 (de) * 2002-07-22 2006-07-06 Siemens Ag Messvorrichtung mit einer Biochip-Anordnung und Verwendung der Vorrichtung für ein Hochdurchsatzanalyseverfahren
GB0223476D0 (en) * 2002-10-09 2002-11-13 The Technology Partnership Plc Detecting apparatus
DE102006057300A1 (de) * 2006-12-05 2008-06-19 Siemens Ag Anordnung zur Aufbereitung einer Mehrzahl von Proben für eine Analyse

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3260413A (en) * 1964-08-31 1966-07-12 Scientific Industries Automatic chemical analyzer
US3526480A (en) * 1966-12-15 1970-09-01 Xerox Corp Automated chemical analyzer
US3607079A (en) * 1969-06-02 1971-09-21 Scientific Industries Analysis arrangement for chemical analyzing apparatus
CH568793A5 (pt) * 1974-02-15 1975-11-14 Mettler Instrumente Ag
DE2502350A1 (de) * 1975-01-22 1976-07-29 Heraeus Gmbh W C Einrichtung zur verteilung einer probe an mehrere analysenkanaele bei der durchfuehrung einer automatischen chemischen vielfachanalyse von fluessigkeiten
FR2353856A1 (fr) * 1976-06-02 1977-12-30 Chateau Guy Ruban destine a servir de support a une reaction par exemple chimique ou biochimique, et procede d'analyse le mettant en oeuvre
DE8033593U1 (de) * 1980-12-18 1981-07-09 Behringwerke Ag, 3550 Marburg Vorrichtung zum transport streifenfoermigen testguts unter eine messeinrichtung
US4618251A (en) * 1981-10-05 1986-10-21 Canon Kabushiki Kaisha Recording apparatus
DE3714294A1 (de) * 1987-04-29 1988-11-10 Hoechst Ag Vorrichtung zum transport von teiltemperiertem, streifenfoermigem testgut
US5004582A (en) * 1987-07-15 1991-04-02 Fuji Photo Film Co., Ltd. Biochemical analysis apparatus
EP0304921B1 (en) * 1987-08-25 1994-11-02 Fuji Photo Film Co., Ltd. Biochemical analysis apparatus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9010874A1 *

Also Published As

Publication number Publication date
DE3908123C2 (pt) 1991-07-11
WO1990010874A1 (de) 1990-09-20
DE3908123A1 (de) 1990-09-20

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