EP0388275B1 - Compositions dermatologiques et cosmétologiques à base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite séborrhéique et/ou des troubles de la séborrhée - Google Patents

Compositions dermatologiques et cosmétologiques à base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite séborrhéique et/ou des troubles de la séborrhée Download PDF

Info

Publication number
EP0388275B1
EP0388275B1 EP90400652A EP90400652A EP0388275B1 EP 0388275 B1 EP0388275 B1 EP 0388275B1 EP 90400652 A EP90400652 A EP 90400652A EP 90400652 A EP90400652 A EP 90400652A EP 0388275 B1 EP0388275 B1 EP 0388275B1
Authority
EP
European Patent Office
Prior art keywords
zinc
process according
alkylcarboxamide
seborrheic
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP90400652A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0388275A1 (fr
Inventor
Pierre Fabre
Michel Jeanjean
Gilbert Mouzin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Dermo Cosmetique SA
Original Assignee
Pierre Fabre Dermo Cosmetique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9379610&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0388275(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pierre Fabre Dermo Cosmetique SA filed Critical Pierre Fabre Dermo Cosmetique SA
Publication of EP0388275A1 publication Critical patent/EP0388275A1/fr
Application granted granted Critical
Publication of EP0388275B1 publication Critical patent/EP0388275B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair

Definitions

  • the present invention carried out at the Pierre FABRE Dermatological and Cosmetological Research Center, relates to new topical formulations usable in dermatology and cosmetology.
  • formulations based on a combination of alkylcarboxamides and zinc salts, potentiate the anti-inflammatory, antipruritic and antiseborrhoeic effects of the active ingredients.
  • the alkylcarboxamide corresponds to the following general formula (I) in which : R represents a hydrogen atom, a C1 to C5 alkyl group or a pyridyl group.
  • R1 and R2 may be the same or different and represent a hydrogen atom or a C1 and C5 alkyl group optionally substituted by a hydroxyl.
  • These compounds of formula I can be prepared by chemical methods known to those skilled in the art and are mentioned by the applicant in patent 87 12788.
  • Alopecic composition comprising Minoxidil (Pierre FABRE, Henri COUSSE and Gilbert MOUZIN).
  • alkylcarboxamide corresponding to the following formula (II): in which R1 is a C1 to C5 alkyl group and is preferably the methyl group and more particularly: N (hydroxy 2 ethyl) acetamide N (hydroxy 3 propyl) acetamide N (hydroxy 2 ethyl) propionamide N (hydroxy 2 ethyl) isopropylacetamide
  • composition according to the invention advantageously contains from 0.5 to 10% by weight of alkylcarboxamides and from 0.1 to 2% by weight of zinc salts.
  • the condition was mainly localized in the face with flaking and pruritus in 39 cases, erythema in 40 cases.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
EP90400652A 1989-03-13 1990-03-13 Compositions dermatologiques et cosmétologiques à base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite séborrhéique et/ou des troubles de la séborrhée Expired - Lifetime EP0388275B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8903235 1989-03-13
FR8903235A FR2644063B1 (fr) 1989-03-13 1989-03-13 Compositions dermatologiques et cosmetologiques a base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite seborrheique et/ou des troubles de la seborrhee

Publications (2)

Publication Number Publication Date
EP0388275A1 EP0388275A1 (fr) 1990-09-19
EP0388275B1 true EP0388275B1 (fr) 1993-02-03

Family

ID=9379610

Family Applications (1)

Application Number Title Priority Date Filing Date
EP90400652A Expired - Lifetime EP0388275B1 (fr) 1989-03-13 1990-03-13 Compositions dermatologiques et cosmétologiques à base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite séborrhéique et/ou des troubles de la séborrhée

Country Status (7)

Country Link
EP (1) EP0388275B1 (enrdf_load_stackoverflow)
AT (1) ATE85219T1 (enrdf_load_stackoverflow)
DE (1) DE69000843T2 (enrdf_load_stackoverflow)
DK (1) DK0388275T3 (enrdf_load_stackoverflow)
ES (1) ES2054283T3 (enrdf_load_stackoverflow)
FR (1) FR2644063B1 (enrdf_load_stackoverflow)
GR (1) GR3007508T3 (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0570405B1 (de) * 1991-02-06 1995-05-24 Beiersdorf Aktiengesellschaft Stabile kosmetische mittel
TW233264B (enrdf_load_stackoverflow) * 1992-02-03 1994-11-01 Otsuka Pharma Co Ltd
FR2710264B1 (fr) * 1993-09-21 1995-12-08 Rocher Yves Biolog Vegetale Utilisation pour le traitement des peaux mixtes d'une quantité efficace de substances actives.
US5599548A (en) * 1995-05-08 1997-02-04 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides and retinol or retinyl ester
FR2740341B1 (fr) * 1995-10-26 1997-12-19 Oreal Utilisation de sel de lanthanide, d'etain, de zinc, de manganese, d'yttrium, de cobalt, de baryum, de strontium dans une composition pour la peau
US5693330A (en) * 1996-04-25 1997-12-02 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing melinamide and a retinoid
US5716627A (en) * 1996-04-25 1998-02-10 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
US5747051A (en) * 1996-09-27 1998-05-05 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid
US5955092A (en) * 1996-09-27 1999-09-21 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester
GB0617191D0 (en) * 2006-08-31 2006-10-11 York Pharma Plc Improvements in pharmaceutical compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016287A (en) * 1972-07-17 1977-04-05 Boehringer Ingelheim Gmbh Dermatological compositions containing an acylamino-carboxylic acid or an alkyl ester thereof
ZA752066B (en) * 1974-05-02 1976-03-31 Draco Ab Dermatologically active preparation
FR2599967B1 (fr) * 1986-06-16 1989-03-31 Bfb Etudes Rech Experimentale Utilisation de sel de zinc et de la vitamine b6 pour enrayer les processus alopeciques et/ou seborrheiques.
AU609090B2 (en) * 1987-02-18 1991-04-26 Milor Scientific, Ltd. Composition for treatment of acne
FR2612774B1 (fr) * 1987-03-27 1990-12-28 Bfb Etudes Rech Experimentale Compositions cosmetiques et pharmaceutiques, utilisees pour traiter le processus de l'alopecie androgenogenetique, contenant de l'acide azelaique

Also Published As

Publication number Publication date
DE69000843D1 (de) 1993-03-18
ES2054283T3 (es) 1994-08-01
FR2644063B1 (fr) 1991-06-14
GR3007508T3 (enrdf_load_stackoverflow) 1993-08-31
DE69000843T2 (de) 1993-07-15
FR2644063A1 (fr) 1990-09-14
EP0388275A1 (fr) 1990-09-19
ATE85219T1 (de) 1993-02-15
DK0388275T3 (da) 1993-03-22

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