EP0351574A2 - Embout de pipette amovible sous forme d'un récipient adapté à la forme d'un élément de réception, en particulier d'un cône de pipette - Google Patents

Embout de pipette amovible sous forme d'un récipient adapté à la forme d'un élément de réception, en particulier d'un cône de pipette Download PDF

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Publication number
EP0351574A2
EP0351574A2 EP89111346A EP89111346A EP0351574A2 EP 0351574 A2 EP0351574 A2 EP 0351574A2 EP 89111346 A EP89111346 A EP 89111346A EP 89111346 A EP89111346 A EP 89111346A EP 0351574 A2 EP0351574 A2 EP 0351574A2
Authority
EP
European Patent Office
Prior art keywords
pipette tip
wall thickness
wall
weakening
pipette
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP89111346A
Other languages
German (de)
English (en)
Other versions
EP0351574B1 (fr
EP0351574A3 (en
Inventor
Ernst Dipl.-Ing. Tennstedt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf Netheler Hinz GmbH
Eppendorf Geraetebau Netheler and Hinz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf Netheler Hinz GmbH, Eppendorf Geraetebau Netheler and Hinz GmbH filed Critical Eppendorf Netheler Hinz GmbH
Priority to AT89111346T priority Critical patent/ATE95728T1/de
Publication of EP0351574A2 publication Critical patent/EP0351574A2/fr
Publication of EP0351574A3 publication Critical patent/EP0351574A3/de
Application granted granted Critical
Publication of EP0351574B1 publication Critical patent/EP0351574B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids

Definitions

  • the invention relates to a plug-on pipette tip in the form of a correspondingly a plug-on head piece, in particular the cone of a pipette, at least in sections, in particular also conical, with an upper plug-on opening and a lower opening for receiving and dispensing a liquid, in which the sealing area, in which the pipette tip comes in contact with the plug-on head piece, is designed to be flexible at a distance from the upper end of the pipette tip with a smooth seat inside the pipette tip wall and by weakening the wall thickness in relation to the pipette tip wall.
  • the invention relates to a form of such a pipette tip in the form of an at least partially conical vessel, in which the sealing area is designed with a smooth seat at a distance from the plug-on opening at the upper end of the pipette tip.
  • a cylindrical design in the area of the plug-on head piece is also reserved.
  • the reference to the smooth seat does not rule out roughening of the surface. In this respect, there can also be slight profiles which improve the seal on the working cone. Basically, a smooth seat is preferred.
  • the plug-on head piece of a pipette can represent a cone per se, which has a passage and is inserted into the conical wall part of the pipette tip.
  • the outwardly projecting push-on headpiece has a spherical surface in its ring-shaped seating area. This also creates a sealing seat, in particular on an elastic and resilient seat surface, of the pipette tip, the elasticity causing the pipette tip to fit tightly against the annular seat region of the plug-on head piece.
  • Pipette tips with a conical seat are known for example from DE PS 10 90 449.
  • the push-on cone is conical over its entire length.
  • a flexibility of the push-on tip itself is included, but only a small tolerance compensation between the cone of the tip and the push-on cone of the pipette is possible. Therefore, leaks have been repeatedly observed in the practical use of this arrangement.
  • Such ribs do not form a secure fit or a quasi smooth seating area.
  • This known version has, for example, only a peripheral edge web at the upper edge goes through with the same wall thickness over the major part of the pipette tip length. At most, the wall thickness is reduced in the area of the lower discharge opening.
  • a pipette tip according to US Pat. No. 4,349,109 is constructed from several sections, the uppermost of which, as a truncated cone, has an inner surface with a conical shape, for example of 3 °, and forms a wedge seat on a pipette.
  • This section with the seat, which forms the sealing area, has the greatest wall thickness of the pipette tip and is therefore particularly unyielding.
  • the seat surface merges through an inclined step surface into the lower wall section of the pipette tip, which is offset with respect to the upper section with the seat surface in order to also make it possible for smaller volume pipettes to find a seat.
  • the upper edge of the lower section is particularly firm and unyielding due to the outwardly projecting wall of the upper section. In this respect, there is no adaptability and, because of the wall offset with respect to a center line, there is also no overlap of wall contours.
  • a plug-on pipette tip of the type specified above which has a wall thickness weakening in the sealing area, so that an adaptation to the conical plug-on head piece can take place.
  • the pipette tip consists of a material, in particular plastic, which is particularly elastic, at least flexible, but preferably has certain recovery properties that are caused when it expands.
  • plastic which is particularly elastic, at least flexible, but preferably has certain recovery properties that are caused when it expands.
  • polypropylene polypropylene
  • the wall thickness weakening already known in this sense has proven itself. This weakening of the wall thickness is arranged on the outside. It either runs around the circumference or is formed in places by groove-like depressions. In the case of the wall thickness weakening arranged on the outside, it is taken into account that this is made stronger at the upper edge of the sealing area than at the lower end of the pipette tip. It is taken into account that there is an annular step on the outside at the upper edge of the sealing area and that the wall thickness of the pipette tip in the sealing area decreases towards the top.
  • Such an embodiment in the arrangement on the outside is also preferably included because it is relatively easy to implement using appropriate injection molds. In practice, however, it has been shown that this measure can only be used to a limited extent from the point of view of demoldability by avoiding undercuts. Especially with slim pipette tips with low conicity, it is very difficult to find an adequate one To achieve wall thickness weakening in the sealing area and to carry out this wall thickness weakening evenly over the entire area of a defined sealing zone. Typically, the wall thickness changes over the sealing area. For this reason, the sealing area of such pipette tips is also poorly visible, which can lead to uncertainties for the user.
  • the present invention is therefore based on the task of creating the pipette tips, in which the extent of the wall thickness weakening can be chosen and produced as desired in an axially limited, clearly visible sealing area, especially with regard to the last-mentioned known embodiment, without damaging undercuts the ability to be removed affect. This applies in particular to slim pipette tips with low conicity up to at least approximately cylindrical designs.
  • the wall thickness weakening is provided by recesses in the pipette tip wall at least in the sealing area outside and inside. Weaknesses in wall thickness are arranged both inside and outside with the advantage that the wall thickness in the seat area or sealing area becomes more uniform, to the extent that an equal wall thickness is created over the entire sealing area.
  • the object is achieved in that an outer wall thickness weakening coming from below and an inner wall thickness weakening coming from above overlap in a defined sealing area.
  • the expression of a weakening of the wall thickness progressing to overlap arises in such a way that it starts directly from the wall and ultimately ends in one step in the weakening.
  • the step lies in the internal weakening of the wall thickness with respect to the insertion opening below and the outer wall thickness weakening above.
  • a preferred feature in an embodiment in which the wall thickness weakening increases from the outside upwards towards the push-on opening towards an upwardly widening step surface for the transition into the normal wall thickness is that the wall thickness weakening inside in the sealing region in the opposite sense from top to bottom increases at the bottom and has a retracted ring step at the lower end. It is conveniently included that the inner conical ring step drawn in downwards has a slight slope of the order of 30 °.
  • the opposite wall thickness weakening which increases in the opposite direction, forms an essentially parallel wall section of the pipette tip in the sealing region between the outside and inside.
  • the inner ring step is preferably used as a stop for the conical plug-on head piece of the pipette tip, whereby the additional advantage of a defined, reproducible seat can be used.
  • the strength of the seat can advantageously be improved further by creating a wall section that runs obliquely to the wall center line of the conical pipette tip and that forms a cone around the central axis of the pipette tip, which forms from the top to the bottom extended and designed in the opposite direction to the cone of the continuous pipette tip wall.
  • the embodiment according to the invention with a wall thickness weakening inside and outside therefore has advantages and, in the preferred embodiment, also enables a particularly simple design of the manufacturing mold while avoiding slides or similar mechanisms that would be required for realizing undercuts.
  • the overlap of the outer and inner wall thickness weakening according to the invention arises after a corresponding design of the molding tools in a simple manner when the inner and outer shape are joined in each injection cycle.
  • the pipette tip 1 has an upper attachment opening 2, which can be widened by an edge bevel.
  • the upper section is bordered by a relatively thick wall 3. This is reinforced on the outside by ribs 4, so that stability is present here. On this wall, a web 3 'running around can still be arranged on the upper edge outside.
  • This wall thickness continues up to area 5 and is uniform. This area ends at 6. Below the transverse line 6, the wall thickness decreases. A longitudinal section, which contains the sealing region 10, adjoins the transverse line 6. This sealing area extends to the transverse line 7. Below this, the pipette tip with essentially the same wall thickness, which is present above the transverse line 6, goes down further to a lower receiving and dispensing opening 8. It should be noted that even is drawn that from the wall thickness below the sealing area 10, the wall thickness can typically taper towards the lower discharge opening.
  • the center surface of the wall of the conical body of the pipette tip 1 is shown with 9 on the whole and drawn by the dash-dotted wall center line. It runs centrally in the wall above cross line 6 and below cross line 7.
  • the sealing area 10 between the transverse lines 6 and 7 - the sealing area not having to extend exactly to these transverse lines, but rather being less in the axial length of the pipette tip - the wall thickness is reduced.
  • a wall thickness weakening 11 which has an inner axial lateral surface 12 which extends at an angle to the wall center line 9. It is at least less conical.
  • a wall thickness weakening 15 is now arranged on the inside. It starts approximately from the point of use of stage 14 and deepens downward approximately to the height of end 13, at which the external weakening of the wall thickness begins.
  • the inner wall thickness weakening 15 now increases downwards, it then passes through a conical ring ring 16 which contracts inwards into the wall 17 of the pipette tip which is of normal thickness.
  • the lower conical ring step 16 drawn in has, for example, a slope of 30 °.
  • outer wall thickness weakening 11 comes from below and the inner wall thickness weakening 15 comes from above with regard to the pipette tip, the top being determined by the plug-on opening 2. This direction results from the increasing thickness of the wall thickness weaknesses in their course, and it can also be seen that the two wall thickness weaknesses 11 and 15 overlap.
  • the wall section 18 between the wall thickness weakenings 11 on the outside and 15 on the inside has the same thickness over the length of the sealing region 10 if the surfaces forming the wall are parallel.
  • FIG. 2 shows an example of a cylindrical design of the pipette tip in the upper region.
  • the pipette tip has a wall 3 with normal, considerable wall thickness.
  • a cylindrical, inner wall thickness weakening 19 goes down to an annular step 20. This wall thickness weakening 19 comes from above.
  • a wall thickness weakening 21 comes from below and ends in an upper, ring ring 22 directed downwards.
  • the sealing area 10 is arranged, in which the two wall thickness weakenings overlap and thus create a considerable wall thickness weakening becomes.
  • This weakening of the wall thickness can be achieved by appropriate dimensioning of the inner diameter 23 and the outer diameter 24, i.e. in the end can be made arbitrarily thin by designing the wall thickness weakenings.
  • FIG. 3 shows an embodiment in which a outer wall thickness weakening 25 coming from the outside ends in an upper conical ring step 26, while an inner wall thickness weakening 27 coming from above ends in a lower conical ring step 28.
  • a wall section 29 with a smaller wall thickness than above and below the sealing area, but the seat surface in the sealing area is conical, essentially with a cone tightening of 1:15.
  • the wall section 29 has less conicity than the overall wall of the pipette tip or the wall center line.
  • the upper wall 3 below the push-on opening 2 is made thicker than the wall in the sealing area and the pipette tip according to FIG. 3 also has a wall 17 of normal thickness below the sealing area.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Closures For Containers (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP89111346A 1988-07-21 1989-06-22 Embout de pipette amovible sous forme d'un récipient adapté à la forme d'un élément de réception, en particulier d'un cône de pipette Expired - Lifetime EP0351574B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT89111346T ATE95728T1 (de) 1988-07-21 1989-06-22 Aufsteckbare pipettenspitze in form eines entsprechend einem aufsteckkopfstueck, insbesondere konus einer pipette, wenigstens abschnittsweise ausgefuehrten gefaesses.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3824767 1988-07-21
DE3824767A DE3824767A1 (de) 1988-07-21 1988-07-21 Aufsteckbare pipettenspitze in form eines entsprechend einem aufsteckkopfstueck, insbesondere konus einer pipette, wenigstens abschnittsweise ausgefuehrten gefaesses

Publications (3)

Publication Number Publication Date
EP0351574A2 true EP0351574A2 (fr) 1990-01-24
EP0351574A3 EP0351574A3 (en) 1990-11-14
EP0351574B1 EP0351574B1 (fr) 1993-10-13

Family

ID=6359207

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89111346A Expired - Lifetime EP0351574B1 (fr) 1988-07-21 1989-06-22 Embout de pipette amovible sous forme d'un récipient adapté à la forme d'un élément de réception, en particulier d'un cône de pipette

Country Status (6)

Country Link
US (1) US4961350A (fr)
EP (1) EP0351574B1 (fr)
JP (1) JP2848632B2 (fr)
AT (1) ATE95728T1 (fr)
DD (1) DD283953A5 (fr)
DE (2) DE3824767A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1862219A1 (fr) * 2006-05-29 2007-12-05 Qiagen GmbH Appareil pour retenir un embout à pipette, embout pour pipette et pipette utilisant ledit embout

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200151A (en) * 1990-05-21 1993-04-06 P B Diagnostic Systems, Inc. Fluid dispensing system having a pipette assembly with preset tip locator
US5192511A (en) * 1991-05-31 1993-03-09 Tri-Continent Scientific, Inc. Pipette tip and piston
US5232669A (en) * 1991-11-08 1993-08-03 Abbott Laboratories Pipette tip with self-aligning and self-sealing features
US5509319A (en) * 1994-06-21 1996-04-23 Geo-Microbial Technologies, Inc. Adapter for pipetter and hypodermic needle
CA2287962C (fr) * 1997-05-02 2007-01-02 Gen-Probe Incorporated Appareil de reaction comprenant plusieurs recipients
US6499363B1 (en) * 1997-12-12 2002-12-31 The Sailor Pen Co., Ltd. Tip for pipette and pipette with the same
WO2000027528A1 (fr) * 1998-11-06 2000-05-18 Rainin Instrument Co., Inc. Pipette a pointe et ensemble axe de montage ameliores
US6168761B1 (en) * 1998-11-06 2001-01-02 Rainin Instrument Co., Inc. Pipette with improved pipette tip and mounting shaft
DE99958813T1 (de) * 1998-11-06 2006-02-09 Rainin Instrument Llc., Oakland Pipette mit verbesserter Pipettenspitze und verbessertem Befestigungsschaft
US6248295B1 (en) * 1998-11-06 2001-06-19 Rainin Instrument Co., Inc. Pipette with improved pipette tip and mounting shaft combination
US6197259B1 (en) * 1998-11-06 2001-03-06 Rainin Instrument Co., Inc. Easy eject pipette tip
DE19917375C2 (de) * 1999-04-16 2001-09-27 Hamilton Bonaduz Ag Bonaduz Pipettiereinheit
US6814936B1 (en) 1999-07-01 2004-11-09 Goran Enhorning Pipette assembly having a small volume disposable tip
US6596240B2 (en) 2001-01-12 2003-07-22 Porex Corporation Pipette tip for easy mounting and ejecting from a pipette
US6973845B2 (en) 2001-01-18 2005-12-13 Beckman Coulter, Inc. Low insertion force tip/mandrel
FI20010972A0 (fi) * 2001-05-09 2001-05-09 Thermo Labsystems Oy Kärkisäiliöpipetti
US6568288B2 (en) * 2001-06-29 2003-05-27 Rainin Instrument, Llc Pipette with improved pipette tip and mounting shaft
DE10135963B4 (de) * 2001-07-24 2005-09-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zum Pipettieren einer Flüssigkeit
DE10222511B4 (de) * 2002-05-22 2005-03-17 Eppendorf Ag Pipettenspitze
US7517694B2 (en) * 2002-07-26 2009-04-14 Ortho-Clinical Diagnostics, Inc. Metering tip with internal features to control fluid meniscus and oscillation
US7641859B2 (en) * 2004-02-11 2010-01-05 Matrix Technologies Corporation Pipette tip mounting and ejection assembly and associated pipette tip
US20050255005A1 (en) * 2004-05-13 2005-11-17 Arta Motadel Stackable pipette tips having increased accuracy
CA2512353A1 (fr) * 2004-07-16 2006-01-16 Stemcell Technologies Inc. Machine a pipette automatisee
US7662344B2 (en) 2006-10-24 2010-02-16 Viaflo Corporation Locking pipette tip and mounting shaft
US7662343B2 (en) 2006-10-24 2010-02-16 Viaflo Corporation Locking pipette tip and mounting shaft
US7794664B2 (en) 2006-11-16 2010-09-14 Idexx Laboratories, Inc. Pipette tip
US8277757B2 (en) * 2009-09-29 2012-10-02 Integra Biosciences Corp. Pipette tip mounting shaft
US9486803B2 (en) 2010-01-22 2016-11-08 Biotix, Inc. Pipette tips
EP3831489A1 (fr) * 2010-01-22 2021-06-09 Biotix, Inc. Extrémités de pipette
US11559802B2 (en) * 2011-07-20 2023-01-24 Avidien Technologies, Inc. Pipette tip adapter
US8795606B2 (en) 2012-05-30 2014-08-05 Biotix, Inc. Integrated pipette tip devices
WO2018213196A1 (fr) 2017-05-17 2018-11-22 Biotix, Inc. Embouts de pipette ergonomiques

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313982A1 (fr) * 1975-06-12 1977-01-07 Eppendorf Geraetebau Netheler Embout rapportable de pipette
EP0148333A1 (fr) * 1983-10-13 1985-07-17 Cetus Corporation Embout à usage unique pour pipette
US4748859A (en) * 1987-03-06 1988-06-07 Rainin Instrument Co., Inc. Disposable pipette tip

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732734A (en) * 1972-05-25 1973-05-15 Centaur Chemical Co Micropipette with disposable tips
US4349109A (en) * 1980-10-20 1982-09-14 Medical Laboratory Automation, Inc. Disposable pipette tips and trays therefor
US4679446A (en) * 1985-09-09 1987-07-14 Baxter Travenol Laboratories, Inc. Multi-volume displacement pipette

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313982A1 (fr) * 1975-06-12 1977-01-07 Eppendorf Geraetebau Netheler Embout rapportable de pipette
EP0148333A1 (fr) * 1983-10-13 1985-07-17 Cetus Corporation Embout à usage unique pour pipette
US4748859A (en) * 1987-03-06 1988-06-07 Rainin Instrument Co., Inc. Disposable pipette tip

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1862219A1 (fr) * 2006-05-29 2007-12-05 Qiagen GmbH Appareil pour retenir un embout à pipette, embout pour pipette et pipette utilisant ledit embout
WO2007137818A1 (fr) * 2006-05-29 2007-12-06 Qiagen Gmbh dispositif de maintien de pointes de pipettes, POINTE DE pipette ainsi que dispositif de pipettage
US8512650B2 (en) 2006-05-29 2013-08-20 Qiagen Gmbh Device for mounting pipette tips, pipette tip, and pipetting device
EP1862219B1 (fr) * 2006-05-29 2018-02-07 Qiagen GmbH Appareil pour retenir un embout à pipette et pipette utilisant ledit embout
EP3885046A1 (fr) 2006-05-29 2021-09-29 QIAGEN GmbH Dispositif de maintien des pointes de pipette et son utilisation

Also Published As

Publication number Publication date
ATE95728T1 (de) 1993-10-15
JPH0268148A (ja) 1990-03-07
DE58905889D1 (de) 1993-11-18
US4961350A (en) 1990-10-09
EP0351574B1 (fr) 1993-10-13
DD283953A5 (de) 1990-10-31
JP2848632B2 (ja) 1999-01-20
DE3824767A1 (de) 1990-02-01
DE3824767C2 (fr) 1990-05-10
EP0351574A3 (en) 1990-11-14

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