EP0338886A1 - Sterile container for the collection of biological samples for analysis purposes - Google Patents
Sterile container for the collection of biological samples for analysis purposes Download PDFInfo
- Publication number
- EP0338886A1 EP0338886A1 EP89400952A EP89400952A EP0338886A1 EP 0338886 A1 EP0338886 A1 EP 0338886A1 EP 89400952 A EP89400952 A EP 89400952A EP 89400952 A EP89400952 A EP 89400952A EP 0338886 A1 EP0338886 A1 EP 0338886A1
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- Prior art keywords
- bottle
- cap
- thread
- handle
- biological sample
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/007—Devices for taking samples of body liquids for taking urine samples
Definitions
- the present invention relates to a sterile container facilitating the collection of an essentially urine biological sample, while considerably limiting the contamination of the latter by possible external germs, called "stains".
- urine sampling for a cytobacteriological examination is carried out in 95% of cases at the home of the patient who collects the urine sample himself in a simple bottle fitted with a screw cap, and brings it to the analysis laboratory.
- the present invention aims to remedy these drawbacks and proposes to create a means for improving the sampling technique, ensuring the quality of the biological sample to allow a better interpretation of the results of the biological analysis.
- the invention relates to a device of the above type, characterized in that it consists of a bottle with open upper end, capped by a first closure means with closed bottom, capped by a second means of closure, the second closure means being intended to cover the open upper end after the removal of the first closure means and introduction of the biological sample into the container.
- the user first removes the closing means of the opening to introduce the sampling sample there, then, he closes this opening using the second closing means which remains in somehow in reserve at the other end of the device.
- the device can thus be closed by sterile sealing means, the sterility of the internal faces of the sealing means at level of the opening having been provided by the first sealing means.
- This invention will therefore find its application in medical biology: coproculture but especially cytobacteriological examination of urine and this latter aspect will be developed as a priority.
- the first closure means is a cover and / or a cap and the second closure means is a cap.
- the first closure means is a cover
- this can be protected from a bacteriological and mechanical point of view, in a complementary manner by a cap.
- the upper end and the lower end are provided with an identical thread and the upper and lower caps are provided with a corresponding thread to be screwed one on the thread of the upper end, the other, on the thread of the lower end in the standby position and then on the thread of the upper end after removal of the first cap and introduction of the biological sample.
- cap can be simply fitted onto the bottle, it is advantageous to screw it as in the embodiment in accordance with the above characteristics.
- the wall of the bottle has on its entire perimeter, a reinforcement outside, overhanging the lower thread, thus constituting a collar, itself hollowed out on its lower face. a gutter intended to receive the free edge of the plug over its entire circumference.
- the wall of the bottle extends downwards and a few millimeters, beyond the circular bottom of the container.
- the bottle is cylindrical with a circular section.
- the bottle has a handle and that it is notably pierced in the middle with a large window.
- the handle can be fixed integrally to the bottle or removably by a hook and window connection.
- the wall of the bottle extends downwards beyond the bottom and constitutes a free circular edge of a lower cylindrical cul de sac and the bottom of the bottle is lined with a bacteriostatic product.
- the bottle has on its wall, about 2/3 of its height, a hook at right angles open at the bottom, allowing to accept a flat handle transversely pierced with a slot at its proximal end and on the flat surface, the handle is longitudinally pierced with a large window in order to prevent possible drops of urine from reaching the fingers of the manipulator.
- the advantage of this invention consists in having a sterile bottle: - the opening of which is initially and provisionally closed hermetically by a sterile sealing means which will no longer be used to close the full bottle, since there is a high risk of having been contaminated during sampling.
- This means will therefore be disposable after opening the bottle; - whose final closure after filling will be done by another shutter means sterile quickly released from the lower part where it was previously fixed, and which will therefore not have suffered any risk of contamination.
- the assembly being provided with a handle making it possible to hold the hand holding the bottle apart from the sterile free edges thereof.
- the patient - holds the bottle by the end of its handle, - open it, and discard the stopper that initially blocked the bottle, - collect the urine sample, - quickly releases, once the bottle is full, the other sterile stopper from the lower part, for immediately and without letting go, use it to close the bottle definitively.
- the invention relates to a device intended to facilitate urine sampling, while eliminating the risks contamination of the biological sample thus collected.
- This device consists of a bottle 100 with an open upper end 101 and a closed bottom 102.
- the open upper end 101 is capped by a first closure means 103 in the form of a cap and the lower end 102 is capped by a second closure means 104 which is in a protected and waiting situation.
- the two caps 103, 104 are internally provided with a thread not shown intended to cooperate with the thread 105 of the upper end and the thread 106 of the lower end.
- the upper end is closed by a detachable cover 107, whether or not covered with the cap 103.
- this cover constitutes with or without the cap 103, the first sealing means.
- the lower end is extended beyond the bottom 102 by a circular free edge 120 forming a lower cul de sac intended to perfect the seal and ensure perfect sterility of the stopper.
- the first sealing means is removed, that is to say the cap 103 and / or the cover 107 to take the sample, then the cap 104 which was previously in a protected situation is used, to close the bottle.
- the bottle 100 can have any shape; in general, it is a cylindrical bottle with circular section.
- This bottle can be made of a rigid plastic material, more or less flexible and having a capacity of approximately 40 ml.
- the cap 104 comes under an external reinforcement 108 constituting a collar and whose lower face is hollowed out of a groove 109 which receives the upper edge 110 of the cap 104 and protects it.
- the membrane or cover 107 which closes the upper opening 101 of the bottle 100 is not covered by a cap; this cover is simply fixed by gluing or in another way on the free edge of the opening 101.
- closure means or caps 103, 104 are simply engaged by friction on the corresponding end of the bottle or even by clipping.
- Figure 2 shows another variant of fixing the lower cap 104A which has a central boss 111 threaded from being screwed into the cavity 112 of the bottom 102 of the bottle partially shown.
- the bottle 100 is provided with a handle or an integral, removable or folding handle.
- this handle is adaptable and, for this purpose, the bottle 100 has a hook 113 curved downwards and the adaptable handle 114 has a shield 115 before, in the form of a cylinder segment circular or more generally of shape corresponding to the shape of the wall of the bottle 100 and extended by a tongue 116 provided at the front with a slot 117 for receiving the hook 113 and at the rear of a large and elongated slot or window 118 over the entire length of the tab 116.
- This handle can also be foldable, for example by means of a hinge.
- the lower cap can be fixed by a paper flange or other adhesive means placed astride the edge of the cap and the flange 107.
- an upper flange not shown, in which the lower edge of the upper cap 103 is housed, always for the purpose of protection against contamination.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
La présente invention a pour objet un récipient stérile facilitant le recueil d'un échantillon biologique essentiellement urinaire, tout en limitant considérablement la contamination de ce dernier par d'éventuels germes extérieurs, dits "de souillure".The present invention relates to a sterile container facilitating the collection of an essentially urine biological sample, while considerably limiting the contamination of the latter by possible external germs, called "stains".
A l'heure actuelle, le prélèvement urinaire en vue d'un examen cytobactériologique s'effectue dans 95 % des cas au domicile du patient qui récolte lui-même l'échantillon urinaire dans un simple flacon muni d'un bouchon à vis, et l'apporte au laboratoire d'analyse.At present, urine sampling for a cytobacteriological examination is carried out in 95% of cases at the home of the patient who collects the urine sample himself in a simple bottle fitted with a screw cap, and brings it to the analysis laboratory.
Les inconvénients d'utiliser un tel flacon sont multiples :
- Au niveau de la technique de prélèvement, la main tenant le flacon sera presque toujours souillée par le jet urinaire car l'échantillon doit être prélevé au milieu de la miction.
- Au niveau de l'étude cytobactériologique, l'interprétation des résultats sera très souvent faussée par la contamination indirecte de l'échantillon urinaire, dont les causes isolées ou associées sont essentiellement :
- Le toucher ou l'effleurement digital des faces internes stériles du bouchon mais aussi et surtout du bord libre de l'ouverture du flacon.
- Le dépôt provisoire du bouchon durant le remplissage du flacon, sur un quelconque support non stérile.
- La chute accidentelle et fréquente du bouchon.The disadvantages of using such a bottle are multiple:
- With regard to the sampling technique, the hand holding the bottle will almost always be soiled by the urine stream because the sample must be collected in the middle of urination.
- At the level of the cytobacteriological study, the interpretation of the results will very often be distorted by the indirect contamination of the urine sample, whose isolated or associated causes are essentially:
- Touch or digital touch sterile internal faces of the cap but also and above all of the free edge of the opening of the bottle.
- Temporary deposit of the stopper during filling of the bottle, on any non-sterile support.
- The accidental and frequent fall of the plug.
L'exposition prolongée de ses faces intérieures stériles à l'air libre non stérile et ce pendant toute la durée de la miction et encore davantage si le bouchon est momentanément égaré, ce qui est loin d'être rare.Prolonged exposure of its sterile inner faces to non-sterile open air throughout the duration of urination and even more if the cap is momentarily lost, which is far from rare.
La présente invention a pour but de remédier à ces inconvénients et se propose de créer un moyen permettant d'améliorer la technique de prélèvement, d'assurer la qualité de l'échantillon biologique pour permettre une meilleure interprétation des résultats de l'analyse biologique.The present invention aims to remedy these drawbacks and proposes to create a means for improving the sampling technique, ensuring the quality of the biological sample to allow a better interpretation of the results of the biological analysis.
A cet effet, l'invention concerne un dispositif du type ci-dessus, caractérisé en ce qu'il se compose d'un flacon à extrémité supérieure ouverte, coiffée par un premier moyen de fermeture à fond fermé, coiffé par un second moyen de fermeture, le second moyen de fermeture étant destiné à coiffer l'extrémité supérieure ouverte après l'enlèvement du premier moyen de fermeture et introduction de l'échantillon biologique dans le récipient.To this end, the invention relates to a device of the above type, characterized in that it consists of a bottle with open upper end, capped by a first closure means with closed bottom, capped by a second means of closure, the second closure means being intended to cover the open upper end after the removal of the first closure means and introduction of the biological sample into the container.
Ainsi, grâce à ce dispositif, l'utilisateur enlève d'abord le moyen d'obturation de l'ouverture pour y introduire l'échantillon de prélèvement puis, il referme cette ouverture à l'aide du second moyen d'obturation qui reste en quelque sorte en réserve à l'autre extrémité du dispositif. Le dispositif peut ainsi être fermé par un moyen d'obturation stérile, la stérilité des faces internes du moyen d'obturation au niveau de l'ouverture ayant été assurée par le premier moyen d'obturation.Thus, thanks to this device, the user first removes the closing means of the opening to introduce the sampling sample there, then, he closes this opening using the second closing means which remains in somehow in reserve at the other end of the device. The device can thus be closed by sterile sealing means, the sterility of the internal faces of the sealing means at level of the opening having been provided by the first sealing means.
Cette invention trouvera donc son application en biologie médicale : coproculture mais surtout examen cytobactériologique des urines et ce dernier aspect sera développé en priorité.This invention will therefore find its application in medical biology: coproculture but especially cytobacteriological examination of urine and this latter aspect will be developed as a priority.
Suivant une autre caractéristique, le premier moyen de fermeture est un opercule et/ou un capuchon et le second moyen de fermeture est un capuchon.According to another characteristic, the first closure means is a cover and / or a cap and the second closure means is a cap.
Lorsque le premier moyen de fermeture est un opercule, celui-ci peut être protégé sur le plan bactériologique et sur le plan mécanique, de manière complémentaire par un capuchon.When the first closure means is a cover, this can be protected from a bacteriological and mechanical point of view, in a complementary manner by a cap.
Suivant une autre caractéristique, l'extrémité supérieure et l'extrémité inférieure sont munies d'un filetage identique et les capuchons supérieur et inférieur sont munis d'un filetage correspondant pour être vissés l'un, sur le filetage de l'extrémité supérieure, l'autre, sur le filetage de l'extrémité inférieure en position d'attente puis sur le filetage de l'extrémité supérieure après enlèvement du premier capuchon et introduction de l'échantillon biologique.According to another characteristic, the upper end and the lower end are provided with an identical thread and the upper and lower caps are provided with a corresponding thread to be screwed one on the thread of the upper end, the other, on the thread of the lower end in the standby position and then on the thread of the upper end after removal of the first cap and introduction of the biological sample.
Bien que le capuchon puisse être simplement emmanché sur le flacon, il est intéressant de le vissé comme dans le mode de réalisation conforme aux caractéristiques ci-dessus.Although the cap can be simply fitted onto the bottle, it is advantageous to screw it as in the embodiment in accordance with the above characteristics.
Afin de mieux préserver la stérilité des faces internes de ce bouchon supplémentaire, la paroi du flacon comporte sur l'ensemble de son périmètre, un renforcement en dehors, surplombant le filetage inférieur, constituant ainsi une collerette, elle-même creusée sur sa face inférieure d'une gouttière destinée à recevoir le bord libre du bouchon sur toute sa circonférence.In order to better preserve the sterility of the internal faces of this additional stopper, the wall of the bottle has on its entire perimeter, a reinforcement outside, overhanging the lower thread, thus constituting a collar, itself hollowed out on its lower face. a gutter intended to receive the free edge of the plug over its entire circumference.
Toujours dans le but de préserver la stéri lité de ce bouchon ''inférieur'', la paroi du flacon se prolonge vers le bas et de quelques millimètres, au-delà du fond circulaire du récipient.Always with the aim of preserving steri lity of this "lower" stopper, the wall of the bottle extends downwards and a few millimeters, beyond the circular bottom of the container.
Suivant une autre caractéristique, le flacon est cylindrique à section circulaire.According to another characteristic, the bottle is cylindrical with a circular section.
Pour faciliter la préhension, il est intéressant que le flacon comporte un manche et que celui-ci soit notamment percé en son milieu d'une large fenêtre.To facilitate gripping, it is advantageous that the bottle has a handle and that it is notably pierced in the middle with a large window.
Le manche peut être fixé solidairement au flacon ou de manière amovible par une liaison à crochet et fenêtre.The handle can be fixed integrally to the bottle or removably by a hook and window connection.
Suivant une autre caractéristique, la paroi du flacon se prolonge vers le bas au-delà du fond et constitue un bord libre circulaire d'un cul de sac cylindrique inférieur et le fond du flacon est garni d'un produit bactériostatique.According to another characteristic, the wall of the bottle extends downwards beyond the bottom and constitutes a free circular edge of a lower cylindrical cul de sac and the bottom of the bottle is lined with a bacteriostatic product.
Ainsi, à titre d'exemple, le flacon comporte sur sa paroi, aux 2/3 environ de sa hauteur, un crochet à angle droit ouvert en bas, permettant d'accepter un manche plat transversalement percé d'une fente à son extrémité proximale et sur la surface plane, le manche est longitudinalement percé d'une large fenêtre afin d'éviter à d'éventuelles gouttes d'urines d'atteindre les doigts du manipulateur.Thus, for example, the bottle has on its wall, about 2/3 of its height, a hook at right angles open at the bottom, allowing to accept a flat handle transversely pierced with a slot at its proximal end and on the flat surface, the handle is longitudinally pierced with a large window in order to prevent possible drops of urine from reaching the fingers of the manipulator.
Ainsi, l'avantage de cette invention consiste à disposer d'un flacon stérile :
- dont l'ouverture est initialement et provisoirement close hermétiquement par un moyen d'obturation stérile qui ne servira plus à refermer le flacon plein, car risquant fort d'avoir été contaminé pendant le prélèvement. Ce moyen sera donc jetable après ouverture du flacon ;
- dont la fermeture définitive après remplissage s'effectuera par un autre moyen obturateur stérile dégagé rapidement de la partie inférieure où il était jusqu'alors fixé, et qui n'aura donc subi aucun risque de contamination.Thus, the advantage of this invention consists in having a sterile bottle:
- the opening of which is initially and provisionally closed hermetically by a sterile sealing means which will no longer be used to close the full bottle, since there is a high risk of having been contaminated during sampling. This means will therefore be disposable after opening the bottle;
- whose final closure after filling will be done by another shutter means sterile quickly released from the lower part where it was previously fixed, and which will therefore not have suffered any risk of contamination.
L'ensemble étant muni d'un manche permettant de tenir éloignée la main tenant le flacon des bords libres stériles de celui-ci.The assembly being provided with a handle making it possible to hold the hand holding the bottle apart from the sterile free edges thereof.
Ainsi, lors du prélèvement urinaire, le patient :
- tient le flacon par l'extrémité de son manche,
- l'ouvre, et jette le bouchon qui obstruait initialement le flacon,
- récolte l'échantillon urinaire,
- dégage rapidement, une fois le flacon plein, l'autre bouchon stérile de la partie inférieure, pour immédiatement et sans le lâcher, s'en servir pour fermer définitivement le flacon.Thus, during urine sampling, the patient:
- holds the bottle by the end of its handle,
- open it, and discard the stopper that initially blocked the bottle,
- collect the urine sample,
- quickly releases, once the bottle is full, the other sterile stopper from the lower part, for immediately and without letting go, use it to close the bottle definitively.
Tous les risques de contamination de l'échantillon urinaire énumérés plus haut ont été ainsi évités.All the risks of contamination of the urine sample listed above were thus avoided.
Pour le prélèvement des selles, le même procédé sera utilisé avec surtout un flacon plus large et un manche rigide résistant et plus long.For the removal of stool, the same process will be used, especially with a larger bottle and a resistant, longer rigid handle.
Une forme simple et préférentielle de réalisation de l'invention est décrite ci-après en référence aux dessins annexés dans lesquels :
- - la figure 1 représente le dispositif selon l'invention, en coupe longitudinale et le manche en perspective,
- - la figure 2 est une vue en coupe d'une variante de l'extrémité inférieure du dispositif selon une variante.
- FIG. 1 represents the device according to the invention, in longitudinal section and the handle in perspective,
- - Figure 2 is a sectional view of a variant of the lower end of the device according to a variant.
Selon le mode de réalisation de la figure 1, l'invention concerne un dispositif destiné à faciliter le prélèvement urinaire, tout en éliminant les risques de contamination de l'échantillon biologique ainsi recueilli. Ce dispositif se compose d'un flacon 100 à extrémité supérieure 101 ouverte et à fond 102 fermé. L'extrémité supérieure ouverte 101 est coiffée par un premier moyen d'obturation 103 en forme de capuchon et l'extrémité inférieure 102 est coiffée par un second moyen d'obturation 104 qui est en situation protégée et en attente. Selon l'exemple de la figure 1, les deux capuchons 103, 104 sont munis intérieurement d'un filetage non représenté destiné à coopérer avec le filetage 105 de l'extrémité supérieure et le filetage 106 de l'extrémité inférieure.According to the embodiment of FIG. 1, the invention relates to a device intended to facilitate urine sampling, while eliminating the risks contamination of the biological sample thus collected. This device consists of a
Selon une variante, l'extrémité supérieure est fermée par un opercule 107 détachable, recouvert ou non du capuchon 103. Dans ce cas, cet opercule constitue avec ou sans le capuchon 103, le premier moyen d'obturation.According to a variant, the upper end is closed by a
A la figure 1, l'extrémité inférieure est prolongée au-delà du fond 102 par un bord libre circulaire 120 formant un cul de sac inférieur destiné à parfaire l'étanchéité et assurer la parfaite stérilité du bouchon.In FIG. 1, the lower end is extended beyond the
Pour l'utilisation, on enlève le premier moyen d'obturation, c'est-à-dire le capuchon 103 et/ou l'opercule 107 pour faire le prélèvement puis on utilise le capuchon 104 qui était jusqu'alors en situation protégée, pour refermer le flacon.For use, the first sealing means is removed, that is to say the
Selon l'invention, le flacon 100 peut avoir une forme quelconque ; de manière générale, il s'agit d'un flacon cylindrique à section circulaire. Ce flacon peut être réalisé en une matière plastique rigide, plus ou moins souple et ayant une capacité d'environ 40 ml.According to the invention, the
Selon la figure 1, le capuchon 104 vient sous un renforcement externe 108 constituant une collerette et dont la face inférieure est creusée d'une gorge 109 qui reçoit le bord supérieur 110 du capuchon 104 et le protège.According to Figure 1, the
Selon l'invention, dans le cas où les capuchons 103 et 104 sont fixés par vissage, leurs filetages sont les mêmes et les filetages 105 et 106 sont également identiques.According to the invention, in the case where the
Pour distinguer les capuchons ou plus généralement les moyens d'obturation 103 et 104, ceux-ci ont une couleur différente.To distinguish the caps or more generally the closure means 103 and 104, these have a different color.
Suivant une variante non représentée, la membrane ou opercule 107 qui ferme l'ouverture 101 supérieure du flacon 100 n'est pas recouverte par un capuchon ; cet opercule est simplement fixé par collage ou d'une autre manière sur le bord libre de l'ouverture 101.According to a variant not shown, the membrane or
Suivant une autre variante non représentée, les moyens d'obturation ou capuchons 103, 104 sont simplement engagés par friction sur l'extrémité correspondante du flacon ou encore par enclipsage.According to another variant not shown, the closure means or
La figure 2 montre une autre variante de fixation du capuchon inférieur 104A qui comporte un bossage central 111 fileté venant se visser dans la cavité 112 du fond 102 du flacon partiellement représenté.Figure 2 shows another variant of fixing the lower cap 104A which has a
Selon l'invention, le flacon 100 est muni d'une poignée ou d'un manche solidaire, amovible ou rabattable. Dans l'exemple de réalisation représenté à la figure 1, ce manche est adaptable et, à cet effet, le flacon 100 comporte un crochet 113 recourbé vers le bas et le manche adaptable 114 comporte un bouclier 115 avant, en forme de segment de cylindre circulaire ou plus généralement de forme correspondant à la forme de la paroi du flacon 100 et prolongé par une languette 116 munie à l'avant d'une fente 117 pour recevoir le crochet 113 et à l'arrière d'une fente ou fenêtre importante et allongée 118 sur toute la longueur de la patte 116.According to the invention, the
Ce manche peut également être rabattable, par exemple par l'intermédiaire d'une charnière.This handle can also be foldable, for example by means of a hinge.
Selon d'autres variantes non décrites, le capuchon inférieur peut être fixé par une collerette de papier ou autre moyen adhésif placé à cheval sur le bord du capuchon et la collerette 107.According to other variants not described, the lower cap can be fixed by a paper flange or other adhesive means placed astride the edge of the cap and the
Suivant une autre variante, il est également prévu une collerette supérieure non représentée dans laquelle vient se loger le bord inférieur du capuchon supérieur 103 toujours dans un but de protection contre la contamination.According to another variant, there is also provided an upper flange, not shown, in which the lower edge of the
Enfin, il peut être intéressant d'introduire dans le flacon un produit bactériostatique pour empêcher la multiplication des germes en cas de souillure.Finally, it may be advantageous to introduce a bacteriostatic product into the bottle to prevent the multiplication of germs in the event of soiling.
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8805100 | 1988-04-18 | ||
FR8805100A FR2630000A1 (en) | 1988-04-18 | 1988-04-18 | BOTTLE FOR COLLECTING AN URINARY BIOLOGICAL SAMPLE FOR CYTOBACTERIOLOGICAL EXAMINATION |
Publications (1)
Publication Number | Publication Date |
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EP0338886A1 true EP0338886A1 (en) | 1989-10-25 |
Family
ID=9365403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP89400952A Withdrawn EP0338886A1 (en) | 1988-04-18 | 1989-04-06 | Sterile container for the collection of biological samples for analysis purposes |
Country Status (7)
Country | Link |
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US (1) | US4982615A (en) |
EP (1) | EP0338886A1 (en) |
JP (1) | JPH0216450A (en) |
DK (1) | DK187089A (en) |
FI (1) | FI891847A (en) |
FR (1) | FR2630000A1 (en) |
NO (1) | NO891568L (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5451375A (en) * | 1993-01-28 | 1995-09-19 | Chemplex Industries, Inc. | Apparatus for trimless sample cup used in X-ray spectroscopy |
US5404764A (en) * | 1994-02-07 | 1995-04-11 | Guest; Rodger L. | Liquid sample container system |
US5442970A (en) * | 1994-06-23 | 1995-08-22 | Hutchins; Charles D. | Water sampling device |
US5454020A (en) * | 1994-07-13 | 1995-09-26 | Chemplex Industries, Inc. | Sample cup adapted for upright horizontal and inclined sample plane geometry systems |
US5630989A (en) * | 1994-08-17 | 1997-05-20 | Chemplex Industries, Inc. | Apparatus for trimless sample cup used in X-ray spectroscopy |
US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US5952178A (en) | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6300077B1 (en) | 1996-08-14 | 2001-10-09 | Exact Sciences Corporation | Methods for the detection of nucleic acids |
US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
US6268136B1 (en) | 1997-06-16 | 2001-07-31 | Exact Science Corporation | Methods for stool sample preparation |
US6406857B1 (en) | 1997-06-16 | 2002-06-18 | Exact Sciences Corporation | Methods for stool sample preparation |
US20020064792A1 (en) * | 1997-11-13 | 2002-05-30 | Lincoln Stephen E. | Database for storage and analysis of full-length sequences |
US6503718B2 (en) | 1999-01-10 | 2003-01-07 | Exact Sciences Corporation | Methods for detecting mutations using primer extension for detecting disease |
US6280947B1 (en) | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
EP1155147B1 (en) | 1999-02-25 | 2006-06-14 | EXACT Sciences Corporation | Methods for preserving dna integrity |
ES2269129T3 (en) | 1999-04-09 | 2007-04-01 | Exact Sciences Corporation | PROCEDURES FOR DETECTING NUCLEIC ACIDS CANCER DEVELOPERS. |
AU4669600A (en) | 1999-05-03 | 2000-11-17 | Exact Laboratories, Inc. | Stool specimen collector |
US6849403B1 (en) | 1999-09-08 | 2005-02-01 | Exact Sciences Corporation | Apparatus and method for drug screening |
US6586177B1 (en) * | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
US6919174B1 (en) | 1999-12-07 | 2005-07-19 | Exact Sciences Corporation | Methods for disease detection |
US7368233B2 (en) * | 1999-12-07 | 2008-05-06 | Exact Sciences Corporation | Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm |
US6796194B1 (en) | 2001-10-09 | 2004-09-28 | San Diego State University | Liquid sampling device |
AU2003213107A1 (en) | 2002-02-15 | 2003-09-09 | Exact Sciences Corporation | Methods for analysis of molecular events |
US7172036B2 (en) * | 2002-06-06 | 2007-02-06 | En Novative Technologies, Inc. | Soil sample containment device and method |
US7216725B2 (en) * | 2002-06-06 | 2007-05-15 | En Novative Technologies, Inc. | Soil sampling system and method that allow headspace screening at spaced intervals without disturbing soil sample |
US20040259101A1 (en) * | 2003-06-20 | 2004-12-23 | Shuber Anthony P. | Methods for disease screening |
JP4594125B2 (en) * | 2004-02-20 | 2010-12-08 | キヤノン株式会社 | Image fixing device |
WO2005113769A1 (en) * | 2004-05-14 | 2005-12-01 | Exact Sciences Corporation | Method for stabilizing biological samples for nucleic acid analysis |
US7014231B1 (en) | 2005-01-11 | 2006-03-21 | Callen Chris D | Pool maintenance device |
US9829446B1 (en) | 2012-03-05 | 2017-11-28 | Chemplex Industries, Inc. | Sample cup and method for mounting a thin film of material across a sample cup |
US9841360B1 (en) | 2012-10-15 | 2017-12-12 | Michael C. Solazzi | Sample cup assembly, system and method for purging |
US9339954B2 (en) | 2013-10-11 | 2016-05-17 | Michael C. Solazzi | Portable sample pulverizing and pelletizing system and method |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1312447A (en) * | 1969-05-14 | 1973-04-04 | Nat Res Dev | Method of continuous addition of a component to a chemical or biological system and apparatus therefor |
US3878571A (en) * | 1973-03-02 | 1975-04-22 | Bard Inc C R | Urine collection device |
US3900019A (en) * | 1973-08-23 | 1975-08-19 | Barbara Ann Logiadis | Urine sampling device and method |
US4046138A (en) * | 1974-08-29 | 1977-09-06 | The Kendall Company | Diagnostic device for liquid samples |
US4064760A (en) * | 1976-12-15 | 1977-12-27 | Ipco Hospital Supply Corporation | Sterile urine collection device |
US4244920A (en) * | 1979-12-10 | 1981-01-13 | Plastronics, Inc. | Specimen collection assembly |
US4428384A (en) * | 1979-08-29 | 1984-01-31 | Concord Laboratories, Inc. | Method and apparatus for collecting urine |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US602324A (en) * | 1898-04-12 | Pan-lifter | ||
GB191003577A (en) * | 1910-02-14 | 1910-12-31 | Georges Lasvignes | Improvements relating to Billiard Tables. |
GB444421A (en) * | 1934-12-03 | 1936-03-20 | Alexander Kennard | A new or improved container in the form of a cup and saucer for cigarettes, foodstuffs, or other articles |
US3777739A (en) * | 1971-12-03 | 1973-12-11 | Concord Lab Inc | Method and apparatus for collecting urine |
US4336880A (en) * | 1979-01-15 | 1982-06-29 | Becton, Dickinson And Company | Preservation of urine specimens |
US4296871A (en) * | 1979-07-23 | 1981-10-27 | Ring Lock Container S. A. | Receptacle with a cover of plastics material |
US4453647A (en) * | 1983-01-26 | 1984-06-12 | Neat Benjamin C | Plastic container having threaded closure |
US4494581A (en) * | 1983-02-18 | 1985-01-22 | Whitman Medical Corporation | Isolation of forestream and midstream portions of collected urine samples |
US4643326A (en) * | 1985-05-24 | 1987-02-17 | Janler Corporation | Drinking cup construction |
-
1988
- 1988-04-18 FR FR8805100A patent/FR2630000A1/en not_active Withdrawn
-
1989
- 1989-04-06 EP EP89400952A patent/EP0338886A1/en not_active Withdrawn
- 1989-04-17 NO NO89891568A patent/NO891568L/en unknown
- 1989-04-18 JP JP1096540A patent/JPH0216450A/en active Pending
- 1989-04-18 US US07/339,652 patent/US4982615A/en not_active Expired - Fee Related
- 1989-04-18 FI FI891847A patent/FI891847A/en not_active IP Right Cessation
- 1989-04-18 DK DK187089A patent/DK187089A/en not_active Application Discontinuation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1312447A (en) * | 1969-05-14 | 1973-04-04 | Nat Res Dev | Method of continuous addition of a component to a chemical or biological system and apparatus therefor |
US3878571A (en) * | 1973-03-02 | 1975-04-22 | Bard Inc C R | Urine collection device |
US3900019A (en) * | 1973-08-23 | 1975-08-19 | Barbara Ann Logiadis | Urine sampling device and method |
US4046138A (en) * | 1974-08-29 | 1977-09-06 | The Kendall Company | Diagnostic device for liquid samples |
US4064760A (en) * | 1976-12-15 | 1977-12-27 | Ipco Hospital Supply Corporation | Sterile urine collection device |
US4428384A (en) * | 1979-08-29 | 1984-01-31 | Concord Laboratories, Inc. | Method and apparatus for collecting urine |
US4244920A (en) * | 1979-12-10 | 1981-01-13 | Plastronics, Inc. | Specimen collection assembly |
Also Published As
Publication number | Publication date |
---|---|
DK187089D0 (en) | 1989-04-18 |
NO891568D0 (en) | 1989-04-17 |
DK187089A (en) | 1989-10-19 |
FI891847A0 (en) | 1989-04-18 |
NO891568L (en) | 1989-10-19 |
FI891847A (en) | 1989-10-19 |
JPH0216450A (en) | 1990-01-19 |
FR2630000A1 (en) | 1989-10-20 |
US4982615A (en) | 1991-01-08 |
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