EP0273987A4 - Nouveaux produits intermediaires noveaux et procede de preparation d'ethers de tetrahydroquinolone. - Google Patents

Nouveaux produits intermediaires noveaux et procede de preparation d'ethers de tetrahydroquinolone.

Info

Publication number
EP0273987A4
EP0273987A4 EP19870904727 EP87904727A EP0273987A4 EP 0273987 A4 EP0273987 A4 EP 0273987A4 EP 19870904727 EP19870904727 EP 19870904727 EP 87904727 A EP87904727 A EP 87904727A EP 0273987 A4 EP0273987 A4 EP 0273987A4
Authority
EP
European Patent Office
Prior art keywords
formula
preparing
tetrahydroquinolone
represented
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19870904727
Other languages
German (de)
English (en)
Other versions
EP0273987A1 (fr
Inventor
Kikuo Igarashi
Hiroshi Nakajima
Shinji Kawai
Takeshi Endo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fuji Chemical Industries Co Ltd
Original Assignee
Fuji Chemical Industries Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP16739486A external-priority patent/JPS6323883A/ja
Priority claimed from JP61167395A external-priority patent/JPS6323867A/ja
Application filed by Fuji Chemical Industries Co Ltd filed Critical Fuji Chemical Industries Co Ltd
Publication of EP0273987A1 publication Critical patent/EP0273987A1/fr
Publication of EP0273987A4 publication Critical patent/EP0273987A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procédé permet de préparer un éther de tétrahydroquinolone ayant la formule (I) et un nouveau produit intermédiaire de formule (VIII) permet de préparer ledit éther. Dans la formule (I), R1 représente un groupe alkyle à chaîne droite ou ramifiée ayant entre 1 et 4 atomes de carbone et R3 représente alkylsulfonyloxyle, arylsulfonyloxyle, acyloxyle, un groupe hydroxyle ou un atome d'halogène. Selon ce procédé, on fait réagir un oxyde de 1,2-propylène 3-substitué ou du 1,2-propanediol 3-substitué avec de l'octahydroquinoline-2,5-dione en présence d'un catalyseur acide afin de produire un composé de formule (VII), que l'on fait alors réagir avec une alkylamine de formule R1-NH2 (dans laquelle R1 est défini comme ci-dessus) afin de produire un nouveau composé de formule (VIII), dans laquelle R1 est défini comme ci-dessus, que l'on fait ensuite réagir avec un réactif déshydrogénant de rupture de chaîne fermée afin d'obtenir le composé de formule (I).
EP19870904727 1986-07-15 1987-07-15 Nouveaux produits intermediaires noveaux et procede de preparation d'ethers de tetrahydroquinolone. Withdrawn EP0273987A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP16739486A JPS6323883A (ja) 1986-07-15 1986-07-15 スピロ〔１，３−ジオキソラン−２，５′−キノリン−２′−オン〕類
JP167395/86 1986-07-15
JP61167395A JPS6323867A (ja) 1986-07-15 1986-07-15 テトラヒドロキノロンエ−テル類の新規製造法
JP167394/86 1986-07-15

Publications (2)

Publication Number Publication Date
EP0273987A1 EP0273987A1 (fr) 1988-07-13
EP0273987A4 true EP0273987A4 (fr) 1988-11-16

Family

ID=26491453

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19870904727 Withdrawn EP0273987A4 (fr) 1986-07-15 1987-07-15 Nouveaux produits intermediaires noveaux et procede de preparation d'ethers de tetrahydroquinolone.

Country Status (2)

Country Link
EP (1) EP0273987A4 (fr)
WO (1) WO1988000585A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102703021B1 (ko) 2022-05-16 2024-09-04 전북대학교산학협력단 의료기기 표면 쾌속 살균장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55118432A (en) * 1979-03-07 1980-09-11 Shionogi & Co Ltd 2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction
JPH05134169A (ja) * 1991-11-12 1993-05-28 Olympus Optical Co Ltd 焦点検出装置

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No relevant documents have been disclosed. *
See also references of WO8800585A1 *

Also Published As

Publication number Publication date
WO1988000585A1 (fr) 1988-01-28
EP0273987A1 (fr) 1988-07-13

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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TCAT At: translation of patent claims filed
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DET De: translation of patent claims
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