JPS55118432A - 2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction - Google Patents

2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction

Info

Publication number
JPS55118432A
JPS55118432A JP2701079A JP2701079A JPS55118432A JP S55118432 A JPS55118432 A JP S55118432A JP 2701079 A JP2701079 A JP 2701079A JP 2701079 A JP2701079 A JP 2701079A JP S55118432 A JPS55118432 A JP S55118432A
Authority
JP
Japan
Prior art keywords
formula
compound
spipo
ring opening
opening reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2701079A
Other languages
Japanese (ja)
Other versions
JPS6259707B2 (en
Inventor
Makiko Sakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP2701079A priority Critical patent/JPS55118432A/en
Priority to CA000346987A priority patent/CA1139760A/en
Priority to US06/127,521 priority patent/US4506079A/en
Priority to CH178780A priority patent/CH646968A5/en
Priority to FR8005051A priority patent/FR2450829A1/en
Priority to GB8007793A priority patent/GB2058745B/en
Priority to DE19803008902 priority patent/DE3008902A1/en
Priority to IT67367/80A priority patent/IT1129805B/en
Publication of JPS55118432A publication Critical patent/JPS55118432A/en
Priority to CA000407793A priority patent/CA1180326A/en
Priority to US06/684,090 priority patent/US4582905A/en
Publication of JPS6259707B2 publication Critical patent/JPS6259707B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

NEW MATERIAL:2-Spiro-1,3-dioxolane compound of formula Ia or formula Ib (X is H, or halogen; Y is halogen, amino, substituted amino, OH, or acyloxy; A is alkylene or alkeynlene which may have heteroatoms of O, N, and S in the chain and may have a substituted group; dotted lines show the presence or the absence of double bond).
EXAMPLE: 4'-Chloromethyl-5-bromo-1-benzenesulfonyl-4, 5, 6, 7-tetrahydroindol-4- spiro-2'-(1, 3)dioxolane of formula IV.
USE: Intermediate for the preparation of aromatic ethers of formula V (vasular dilators, hypotensives, etc.) having a central nervous system stimulating activity.
PROCESS: For example, a cyclohexenone compound of formula IIa or formula IIb is condensed with propanediol of formula III to afford a compound of formula Ia or formula Ib.
COPYRIGHT: (C)1980,JPO&Japio
JP2701079A 1979-03-07 1979-03-07 2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction Granted JPS55118432A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP2701079A JPS55118432A (en) 1979-03-07 1979-03-07 2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction
CA000346987A CA1139760A (en) 1979-03-07 1980-03-04 1,4-dioxaspiro¬4,5| decene compounds
US06/127,521 US4506079A (en) 1979-03-07 1980-03-05 Process for preparing indoles
CH178780A CH646968A5 (en) 1979-03-07 1980-03-06 1,4-DIOXASPIRO (4,5) DECENE COMPOUNDS AND METHOD FOR PRODUCING 2-HYDROXY-3-SUBSTITUTED PROPYLARYLAETHERS.
FR8005051A FR2450829A1 (en) 1979-03-07 1980-03-06 PROCESS FOR THE PREPARATION OF 1,4-DIOXASPIRO- (4,5) DECENE COMPOUNDS AND NOVEL PRODUCTS THUS OBTAINED
GB8007793A GB2058745B (en) 1979-03-07 1980-03-07 1,4-dioxospiro(4,5)decene compounds
DE19803008902 DE3008902A1 (en) 1979-03-07 1980-03-07 1,4-DIOXASPIRO SQUARE CLAMP ON 4.5 SQUARE CLAMP FOR DECEN DERIVATIVES
IT67367/80A IT1129805B (en) 1979-03-07 1980-03-07 COMPOUNDS OF 1 4 DIOSSASPIRO 4 5 DE CENE PARTICULARLY USEFUL AS IN TERMEDI FOR THE PREPARATION OF BETA CLINICAL LOCK
CA000407793A CA1180326A (en) 1979-03-07 1982-07-21 1,4-dioxaspiro[4,5]decene compounds
US06/684,090 US4582905A (en) 1979-03-07 1984-12-20 1,4-Dioxaspiro(4,5)decene compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2701079A JPS55118432A (en) 1979-03-07 1979-03-07 2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction

Publications (2)

Publication Number Publication Date
JPS55118432A true JPS55118432A (en) 1980-09-11
JPS6259707B2 JPS6259707B2 (en) 1987-12-12

Family

ID=12209130

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2701079A Granted JPS55118432A (en) 1979-03-07 1979-03-07 2-spipo-1,3-dioxolane compound and new synthesis of aromatic ether by its ring opening reaction

Country Status (1)

Country Link
JP (1) JPS55118432A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57131788A (en) * 1981-01-13 1982-08-14 Yasumitsu Tamura 1,7-naphthyridine derivative
JPS58105931A (en) * 1981-12-17 1983-06-24 Shionogi & Co Ltd Preparation of aryloxypropanol derivative
WO1988000585A1 (en) * 1986-07-15 1988-01-28 Fuji Kagaku Kogyo Kabushiki Kaisha Process for preparing tetrahydroquinolone ethers and novel intermediates therefor

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS643208A (en) * 1987-06-23 1989-01-09 Honda Motor Co Ltd Tappet valve system for internal combustion engine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57131788A (en) * 1981-01-13 1982-08-14 Yasumitsu Tamura 1,7-naphthyridine derivative
JPS58105931A (en) * 1981-12-17 1983-06-24 Shionogi & Co Ltd Preparation of aryloxypropanol derivative
WO1988000585A1 (en) * 1986-07-15 1988-01-28 Fuji Kagaku Kogyo Kabushiki Kaisha Process for preparing tetrahydroquinolone ethers and novel intermediates therefor

Also Published As

Publication number Publication date
JPS6259707B2 (en) 1987-12-12

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