EP0199769A4 - Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides. - Google Patents

Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides.

Info

Publication number
EP0199769A4
EP0199769A4 EP19850905376 EP85905376A EP0199769A4 EP 0199769 A4 EP0199769 A4 EP 0199769A4 EP 19850905376 EP19850905376 EP 19850905376 EP 85905376 A EP85905376 A EP 85905376A EP 0199769 A4 EP0199769 A4 EP 0199769A4
Authority
EP
European Patent Office
Prior art keywords
polypeptides
encoding
nucleic acid
acid sequences
growth factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19850905376
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0199769A1 (en
Inventor
Joseph P Brown
Daniel R Twardzik
Hans Marquardt
George J Todaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of EP0199769A1 publication Critical patent/EP0199769A1/en
Publication of EP0199769A4 publication Critical patent/EP0199769A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP19850905376 1984-10-30 1985-10-23 Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides. Withdrawn EP0199769A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66652084A 1984-10-30 1984-10-30
US666520 1984-10-30

Publications (2)

Publication Number Publication Date
EP0199769A1 EP0199769A1 (en) 1986-11-05
EP0199769A4 true EP0199769A4 (en) 1989-11-29

Family

ID=24674411

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850905376 Withdrawn EP0199769A4 (en) 1984-10-30 1985-10-23 Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides.

Country Status (12)

Country Link
EP (1) EP0199769A4 (enrdf_load_stackoverflow)
JP (1) JPS62501071A (enrdf_load_stackoverflow)
AU (2) AU600433B2 (enrdf_load_stackoverflow)
ES (7) ES8702925A1 (enrdf_load_stackoverflow)
FI (1) FI862734A7 (enrdf_load_stackoverflow)
GR (1) GR852610B (enrdf_load_stackoverflow)
IL (1) IL76866A0 (enrdf_load_stackoverflow)
NO (1) NO862613D0 (enrdf_load_stackoverflow)
NZ (1) NZ213984A (enrdf_load_stackoverflow)
PH (2) PH24603A (enrdf_load_stackoverflow)
PT (1) PT81408B (enrdf_load_stackoverflow)
WO (1) WO1986002650A1 (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240912A (en) * 1983-05-09 1993-08-31 Todaro George J Transforming growth factor (TGF) peptides
US4863899A (en) * 1983-05-09 1989-09-05 Todaro George J Biologically active polypeptides
JPS63167797A (ja) * 1985-12-18 1988-07-11 マイクロジエネシス，インコ−ポレイテイド 選択された昆虫宿主細胞中で選択されたポリペプチドを製造する方法
IL89673A0 (en) * 1988-03-24 1989-09-28 Oncogen Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE38892B1 (en) * 1973-03-28 1978-06-21 Ici Ltd Pharmaceutical compositions
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
US4230691A (en) * 1978-05-23 1980-10-28 The Massachusetts General Hospital Nerve growth factor antibody and process
DK339781A (da) * 1980-08-05 1982-02-06 Searle & Co Syntetisk gen
JPH064673B2 (ja) * 1980-11-10 1994-01-19 ゲネンテツク・インコ−ポレ−テツド ハイブリド型ヒト白血球インタフエロン
WO1985002198A1 (en) * 1983-11-01 1985-05-23 Amgen Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides
GB8507666D0 (en) * 1985-03-25 1985-05-01 Wellcome Found Epidermal growth factor production

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Journal of Biological Chemistry, Vol. 248, No. 22, November 25, 1973, pages 7669-7672; US, C.R. SAVAGE Jr. et al.: "Epidermal growth factor", Figure 1. *
Proc. Natl. Acad. Sci. USA, Vol. 81, December 1984, Biochemistry, pages 7363-7367; US, M.C. BLOMQUIST et al.: "Vaccinia virus 19-kilodalton protein: Relationship to several mammalian proteins, including two growth factors", whole article. *
Proc. of the Montreux 1989 Intern. Chemical Information Conf., Montreux, September 26-28, 1989, pages 131-139, C. SUHR: "Hypertrophic generic structures in patent claims: an extravagance and a remedy for it". *
See also references of WO8602650A1 *

Also Published As

Publication number Publication date
FI862734L (fi) 1986-06-26
JPS62501071A (ja) 1987-04-30
GR852610B (enrdf_load_stackoverflow) 1986-03-04
AU6655190A (en) 1991-01-24
ES8802074A1 (es) 1988-03-16
WO1986002650A1 (en) 1986-05-09
NO862613L (no) 1986-06-27
ES557145A0 (es) 1987-08-16
NO862613D0 (no) 1986-06-27
ES557710A0 (es) 1988-01-01
PT81408B (pt) 1987-11-11
FI862734A0 (fi) 1986-06-26
PH24603A (en) 1990-08-17
ES554630A0 (es) 1988-03-16
ES8801378A1 (es) 1988-01-01
AU633377B2 (en) 1993-01-28
AU4868785A (en) 1986-05-15
PH25794A (enrdf_load_stackoverflow) 1991-11-05
ES8802185A1 (es) 1988-04-01
ES548316A0 (es) 1987-01-16
FI862734A7 (fi) 1986-06-26
AU600433B2 (en) 1990-08-16
NZ213984A (en) 1991-05-28
ES554628A0 (es) 1988-03-16
ES554629A0 (es) 1988-04-01
ES8702925A1 (es) 1987-01-16
PT81408A (en) 1985-11-01
ES557708A0 (es) 1988-01-01
ES8707741A1 (es) 1987-08-16
ES8801379A1 (es) 1988-01-01
IL76866A0 (en) 1986-02-28
EP0199769A1 (en) 1986-11-05
ES8802061A1 (es) 1988-03-16

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19860926

A4 Supplementary search report drawn up and despatched

Effective date: 19891129

17Q First examination report despatched

Effective date: 19910212

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930309

RIN1 Information on inventor provided before grant (corrected)

Inventor name: MARQUARDT, HANS

Inventor name: TODARO, GEORGE, J.

Inventor name: BROWN, JOSEPH, P.

Inventor name: TWARDZIK, DANIEL, R.