AU600433B2 - Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides - Google Patents
Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptidesInfo
- Publication number
- AU600433B2 AU600433B2 AU48687/85A AU4868785A AU600433B2 AU 600433 B2 AU600433 B2 AU 600433B2 AU 48687/85 A AU48687/85 A AU 48687/85A AU 4868785 A AU4868785 A AU 4868785A AU 600433 B2 AU600433 B2 AU 600433B2
- Authority
- AU
- Australia
- Prior art keywords
- amino acid
- carbon atoms
- neutral
- aliphatic
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 239000002243 precursor Substances 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000000159 protein binding assay Methods 0.000 description 1
- 239000012474 protein marker Substances 0.000 description 1
- 238000007388 punch biopsy Methods 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 206010041823 squamous cell carcinoma Diseases 0.000 description 1
- 210000001913 submandibular gland Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229960000814 tetanus toxoid Drugs 0.000 description 1
- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66652084A | 1984-10-30 | 1984-10-30 | |
| US666520 | 1984-10-30 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU66551/90A Division AU633377B2 (en) | 1984-10-30 | 1990-11-12 | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4868785A AU4868785A (en) | 1986-05-15 |
| AU600433B2 true AU600433B2 (en) | 1990-08-16 |
Family
ID=24674411
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU48687/85A Ceased AU600433B2 (en) | 1984-10-30 | 1985-10-23 | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
| AU66551/90A Ceased AU633377B2 (en) | 1984-10-30 | 1990-11-12 | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU66551/90A Ceased AU633377B2 (en) | 1984-10-30 | 1990-11-12 | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
Country Status (12)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5240912A (en) * | 1983-05-09 | 1993-08-31 | Todaro George J | Transforming growth factor (TGF) peptides |
| US4863899A (en) * | 1983-05-09 | 1989-09-05 | Todaro George J | Biologically active polypeptides |
| JPS63167797A (ja) * | 1985-12-18 | 1988-07-11 | マイクロジエネシス，インコ−ポレイテイド | 選択された昆虫宿主細胞中で選択されたポリペプチドを製造する方法 |
| IL89673A0 (en) * | 1988-03-24 | 1989-09-28 | Oncogen | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0046039A1 (en) * | 1980-08-05 | 1982-02-17 | G.D. Searle & Co. | Synthetic urogastrone gene, corresponding plasmid recombinants, transformed cells, production thereof and urogastrone expression |
| AU5523686A (en) * | 1985-03-25 | 1986-10-02 | Wellcome Foundation Limited, The | Epidermal growth factor production and method to depilate animals such as sheep |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE38892B1 (en) * | 1973-03-28 | 1978-06-21 | Ici Ltd | Pharmaceutical compositions |
| US4366246A (en) * | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
| US4230691A (en) * | 1978-05-23 | 1980-10-28 | The Massachusetts General Hospital | Nerve growth factor antibody and process |
| JPH064673B2 (ja) * | 1980-11-10 | 1994-01-19 | ゲネンテツク・インコ−ポレ−テツド | ハイブリド型ヒト白血球インタフエロン |
| WO1985002198A1 (en) * | 1983-11-01 | 1985-05-23 | Amgen | Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides |
-
1985
- 1985-10-23 EP EP19850905376 patent/EP0199769A4/en not_active Withdrawn
- 1985-10-23 FI FI862734A patent/FI862734A7/fi not_active IP Right Cessation
- 1985-10-23 WO PCT/US1985/002103 patent/WO1986002650A1/en not_active Application Discontinuation
- 1985-10-23 AU AU48687/85A patent/AU600433B2/en not_active Ceased
- 1985-10-23 JP JP60504725A patent/JPS62501071A/ja active Pending
- 1985-10-28 IL IL76866A patent/IL76866A0/xx unknown
- 1985-10-29 GR GR852610A patent/GR852610B/el unknown
- 1985-10-29 NZ NZ213984A patent/NZ213984A/en unknown
- 1985-10-29 ES ES548316A patent/ES8702925A1/es not_active Expired
- 1985-10-30 PH PH32995A patent/PH24603A/en unknown
- 1985-10-30 PT PT81408A patent/PT81408B/pt not_active IP Right Cessation
-
1986
- 1986-04-30 ES ES554630A patent/ES8802074A1/es not_active Expired
- 1986-04-30 ES ES554628A patent/ES8802061A1/es not_active Expired
- 1986-04-30 ES ES554629A patent/ES8802185A1/es not_active Expired
- 1986-06-27 NO NO1986862613A patent/NO862613D0/no unknown
- 1986-10-24 ES ES557145A patent/ES8707741A1/es not_active Expired
-
1987
- 1987-09-01 ES ES557710A patent/ES8801379A1/es not_active Expired
- 1987-09-01 ES ES557708A patent/ES8801378A1/es not_active Expired
-
1989
- 1989-03-27 PH PH38379A patent/PH25794A/en unknown
-
1990
- 1990-11-12 AU AU66551/90A patent/AU633377B2/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0046039A1 (en) * | 1980-08-05 | 1982-02-17 | G.D. Searle & Co. | Synthetic urogastrone gene, corresponding plasmid recombinants, transformed cells, production thereof and urogastrone expression |
| AU5523686A (en) * | 1985-03-25 | 1986-10-02 | Wellcome Foundation Limited, The | Epidermal growth factor production and method to depilate animals such as sheep |
Also Published As
| Publication number | Publication date |
|---|---|
| FI862734L (fi) | 1986-06-26 |
| JPS62501071A (ja) | 1987-04-30 |
| GR852610B (enrdf_load_stackoverflow) | 1986-03-04 |
| AU6655190A (en) | 1991-01-24 |
| ES8802074A1 (es) | 1988-03-16 |
| WO1986002650A1 (en) | 1986-05-09 |
| NO862613L (no) | 1986-06-27 |
| ES557145A0 (es) | 1987-08-16 |
| NO862613D0 (no) | 1986-06-27 |
| ES557710A0 (es) | 1988-01-01 |
| PT81408B (pt) | 1987-11-11 |
| FI862734A0 (fi) | 1986-06-26 |
| PH24603A (en) | 1990-08-17 |
| EP0199769A4 (en) | 1989-11-29 |
| ES554630A0 (es) | 1988-03-16 |
| ES8801378A1 (es) | 1988-01-01 |
| AU633377B2 (en) | 1993-01-28 |
| AU4868785A (en) | 1986-05-15 |
| PH25794A (enrdf_load_stackoverflow) | 1991-11-05 |
| ES8802185A1 (es) | 1988-04-01 |
| ES548316A0 (es) | 1987-01-16 |
| FI862734A7 (fi) | 1986-06-26 |
| NZ213984A (en) | 1991-05-28 |
| ES554628A0 (es) | 1988-03-16 |
| ES554629A0 (es) | 1988-04-01 |
| ES8702925A1 (es) | 1987-01-16 |
| PT81408A (en) | 1985-11-01 |
| ES557708A0 (es) | 1988-01-01 |
| ES8707741A1 (es) | 1987-08-16 |
| ES8801379A1 (es) | 1988-01-01 |
| IL76866A0 (en) | 1986-02-28 |
| EP0199769A1 (en) | 1986-11-05 |
| ES8802061A1 (es) | 1988-03-16 |
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