EP0171333A1 - Disposable container for the packaging of pharmaceutical ampoules filled under vacuum - Google Patents

Disposable container for the packaging of pharmaceutical ampoules filled under vacuum Download PDF

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Publication number
EP0171333A1
EP0171333A1 EP85401584A EP85401584A EP0171333A1 EP 0171333 A1 EP0171333 A1 EP 0171333A1 EP 85401584 A EP85401584 A EP 85401584A EP 85401584 A EP85401584 A EP 85401584A EP 0171333 A1 EP0171333 A1 EP 0171333A1
Authority
EP
European Patent Office
Prior art keywords
tray
ampoules
uprights
vicinity
tray according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP85401584A
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German (de)
French (fr)
Other versions
EP0171333B1 (en
Inventor
Maurice Petit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EURINVAL INDUSTRIE
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EURINVAL INDUSTRIE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EURINVAL INDUSTRIE filed Critical EURINVAL INDUSTRIE
Priority to AT85401584T priority Critical patent/ATE34360T1/en
Publication of EP0171333A1 publication Critical patent/EP0171333A1/en
Application granted granted Critical
Publication of EP0171333B1 publication Critical patent/EP0171333B1/en
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/38—Baskets or like containers of skeleton or apertured construction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
    • B65D85/30—Containers, packaging elements or packages, specially adapted for particular articles or materials for articles particularly sensitive to damage by shock or pressure
    • B65D85/42—Containers, packaging elements or packages, specially adapted for particular articles or materials for articles particularly sensitive to damage by shock or pressure for ampoules; for lamp bulbs; for electronic valves or tubes

Definitions

  • the invention relates to a disposable tray for packaging pharmaceutical ampoules to be filled under vacuum.
  • One of the aims of the invention is to overcome the problems associated with dust from overpacks, and with the cleaning of crystallizers.
  • Another object of the invention is to propose crystallizers at low cost price and easy to use, suitable for stacking under vacuum.
  • the subject of the invention is a disposable tray for packaging pharmaceutical ampoules to be filled under vacuum, of the type in which the ampoules are arranged vertically side by side, characterized in that it consists of a flat square bottom, of a belt slightly wider than the bottom and oblique uprights to connect the bottom to the belt.
  • the tray according to the invention is made of plastic material resistant to autoclave temperatures, ie 120 ° C.
  • polypropylene possibly loaded with up to 20% talc, can be used.
  • This tray has a flat and square bottom 1, a belt 2 constituting the edge of the tray and uprights 3, 4, 5 on the side and 6 at an angle, to connect the bottom 1 to the belt 2.
  • the edges of the bottom 1 have a rib 7 intended to hold the tip of the ampoules to be filled, which are arranged vertically against each other in the tray.
  • This rib 7 has, in the vicinity of the angles, small grooves 8 to allow the flow of any liquid, such as a bulb filling liquid or washing water.
  • the belt 2 is slightly wider than the bottom 1.
  • the length of the uprights is such that, generally, the belt is located near the middle of the bulbs.
  • the first is that they are not straight but angular: they indeed have a first part 9 in the vicinity of the bottom, more inclined to the vertical than the second part 10 in the vicinity of the belt.
  • the articulation line 11 is visible in FIG. 3. This arrangement of the uprights facilitates stacking of the trays without deformation.
  • the tray according to the invention With the tray according to the invention, all the bulbs are at the same height because the bottom is very flat. It is therefore possible to stack several full trays without difficulty on a support plate placed on a pallet.
  • the trays located at the top of the piles can advantageously be covered with an inverted tray to protect the openings of the bulbs from external shocks.
  • the assembly is then wrapped in a retractable cover, thus protecting the assembly from any external dust.
  • the trays On arrival at the filling laboratory, the trays are handled with their ampoules and they accompany these ampoules during vacuum filling operations, autoclaving, washing, welding, etc. After packaging bulbs on easel, the trays are stacked after relative rotation of 90 °. They can be destroyed, or reused in other applications.
  • two uprights are provided, but the arrangement of which is not identical to that of the two uprights 4 and 5 on the other adjacent side, so as not to stack up on an upright.
  • a stop such as 12, so as to ensure the stacking of empty trays, without deformation.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Packaging Frangible Articles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Packages (AREA)
  • Vacuum Packaging (AREA)

Abstract

1. Disposable plastic container for the packaging of ampoules filled under vacuum, in which the ampoules are arranged vertically side by side, the tips of the ampoules being supported on a square base (1), the container having an encircling member (2) in the vicinity of the middle of the ampoules slightly wider than the base (1) and oblique uprights (3-6) connecting the base (1) to the encircling member (2), characterized in that no two adjacent sides of the container have the same number of uprights, and that the uprights are angular and comprise a first part (9) in the vicinity of the base (1) and a second part (10) in the vicinity of the encircling member (2), the first part being more inclined to the vertical than the second.

Description

L'invention concerne une barquette jetable pour le conditionnement des ampoules pharmaceutiques à remplir sous vide.The invention relates to a disposable tray for packaging pharmaceutical ampoules to be filled under vacuum.

Actuellement, les ampoules pharmaceutiques destinées à être remplies sous vide sont scellées d'un seul côté, et sont placées debout côte à côte dans des cristallisoirs munis de couvercles. Ces cristallisoirs fermés sont regroupés dans des suremballages en métal, ou plus généralement en carton, puis livrés aux laboratoires. Les cristallisoirs et même les suremballages sont réutilisables, et sont renvoyés au fabricant après le remplissage des ampoules et leur mise sur chevalets. Avant leur réutilisation, les cristallisoirs doivent être comptés et lavés, et les suremballages doivent être nettoyés et dépoussiérés. Le problème posé par la poussière est particulièrement aigu dans le cas des suremballages en carton.Currently, pharmaceutical ampoules intended to be filled under vacuum are sealed on one side, and are placed side by side in crystallizers equipped with lids. These closed crystallizers are grouped in metal overpacks, or more generally in cardboard, then delivered to laboratories. The crystallizers and even the overpacks are reusable, and are returned to the manufacturer after the ampoules have been filled and placed on easels. Before their reuse, the crystallizers must be counted and washed, and the overpacks must be cleaned and dusted. The dust problem is particularly acute in the case of cardboard overpacks.

L'un des buts de l'invention est de s'affranchir des problèmes liés à la poussière des suremballages, et au nettoyage des cristallisoirs. Un autre but de l'invention est de proposer des cristallisoirs à bas prix de revient et à mise en oeuvre aisée, adaptés pour le gerbage à vide.One of the aims of the invention is to overcome the problems associated with dust from overpacks, and with the cleaning of crystallizers. Another object of the invention is to propose crystallizers at low cost price and easy to use, suitable for stacking under vacuum.

L'invention a pour objet une barquette jetable pour le conditionnement des ampoules pharmaceutiques à remplir sous vide, du type dans lequel les ampoules sont disposées verticalement côte à côte, caractérisée en ce qu'elle est constituée d'un fond carré plat, d'une ceinture légèrement plus large que le fond et de montants obliques pour relier le fond à la ceinture.The subject of the invention is a disposable tray for packaging pharmaceutical ampoules to be filled under vacuum, of the type in which the ampoules are arranged vertically side by side, characterized in that it consists of a flat square bottom, of a belt slightly wider than the bottom and oblique uprights to connect the bottom to the belt.

Selon d'autres caractéristiques de l'invention :

  • - le fond est bordé d'une nervure pour assurer le maintien des ampoules ;
  • - au voisinage des angles, ladite nervure présente des saignées pour l'évacuation d'un liquide éventuel ;
  • - les montants comportent une première partie au voisinage du fond, et une seconde partie au voisinage de la ceinture, la première partie étant plus inclinée sur la verticale que la seconde ;
  • - la barquette est constituée en matière plastique du type polypropylène chargé jusqu'à 20 % de talc ;
  • - deux côtés adjacents de la barquette présentent l'un deux montants régulièrement répartis, l'autre un seul montant en son milieu ;
  • - pour le gerbage à vide, elle est décalée de 90° par rapport à la barquette inférieure pour éviter les déformations ;
  • - lorsqu'elle est pleine d'ampoules à remplir, la barquette est gerbable pour expédition sur palette, la barquette du haut de chaque pile étant recouverte d'une barquette vide retournée, et l'ensemble des piles étant scellé sous housse rétractable.
According to other characteristics of the invention:
  • - the bottom is bordered by a rib to ensure the maintenance of the bulbs;
  • - In the vicinity of the angles, said rib has grooves for the evacuation of any liquid;
  • - The uprights have a first part in the vicinity of the bottom, and a second part in the vicinity of the belt, the first part being more inclined to the vertical than the second;
  • - the tray is made of plastic of the polypropylene type loaded with up to 20% talc;
  • - Two adjacent sides of the tray have one two regularly distributed uprights, the other a single upright in the middle;
  • - for empty stacking, it is offset by 90 ° with respect to the lower tray to avoid deformation;
  • - when it is full of ampoules to be filled, the tray is stackable for shipping on a pallet, the tray at the top of each stack being covered with an empty overturned tray, and all of the batteries being sealed in a retractable cover.

D'autres caractéristiques ressortiront de la description qui suit faite avec référence au dessin annexé sur lequel on peut voir :

  • Figure 1, une vue en perspective d'un mode de réalisation d'une barquette selon l'invention ;
  • Figure 2, une vue en perspective de la barquette de la figure 1 après rotation de 90° ;
  • Figure 3, une vue en coupe selon un plan médian, de la barquette de la figure 2, à plus grande échelle.
Other characteristics will emerge from the following description made with reference to the appended drawing in which we can see:
  • Figure 1, a perspective view of an embodiment of a tray according to the invention;
  • Figure 2, a perspective view of the tray of Figure 1 after rotation of 90 °;
  • Figure 3, a sectional view along a median plane of the tray of Figure 2, on a larger scale.

En se reportant au dessin, on voit que la barquette selon l'invention est réalisée en matière plastique résistant aux températures d'autoclave, soit 120°C. Dans un exemple de réalisation particulier, on peut utiliser du polypropylène, éventuellement chargé jusqu'à 20 % de talc.Referring to the drawing, it can be seen that the tray according to the invention is made of plastic material resistant to autoclave temperatures, ie 120 ° C. In a particular embodiment, polypropylene, possibly loaded with up to 20% talc, can be used.

Cette barquette présente un fond 1 plat et carré, une ceinture 2 constituant le bord de la barquette et des montants 3, 4, 5 de côté et 6 d'angle, pour relier le fond 1 à la ceinture 2. Les bords du fond 1 présentent une nervure 7 destinée à maintenir la pointe des ampoules à remplir, qui sont disposées verticalement les unes contre les autres dans la barquette. Cette nervure 7 présente, au voisinage des angles, de petites saignées 8 pour permettre l'écoulement d'un liquide éventuel, tel qu'un liquide de remplissage d'ampoule ou une eau de lavage. Pour tenir compte de la forme des ampoules, cylindrique avec pointes axiales, la ceinture 2 est légèrement plus large que le fond 1. La longueur des montants est telle que, généralement, la ceinture se trouve au voisinage du milieu des ampoules.This tray has a flat and square bottom 1, a belt 2 constituting the edge of the tray and uprights 3, 4, 5 on the side and 6 at an angle, to connect the bottom 1 to the belt 2. The edges of the bottom 1 have a rib 7 intended to hold the tip of the ampoules to be filled, which are arranged vertically against each other in the tray. This rib 7 has, in the vicinity of the angles, small grooves 8 to allow the flow of any liquid, such as a bulb filling liquid or washing water. To take into account the shape of the bulbs, cylindrical with axial points, the belt 2 is slightly wider than the bottom 1. The length of the uprights is such that, generally, the belt is located near the middle of the bulbs.

En dehors du fait qu'ils sont disposés obliquement, les montants présentent deux particularités.Apart from the fact that they are arranged obliquely, the amounts have two particularities.

La première est qu'ils ne sont pas droits mais anguleux : ils comportent en effet une première partie 9 au voisinage du fond, plus inclinée sur la verticale que la seconde partie 10 au voisinage de la ceinture. La ligne d'articulation 11 est visible sur la figure 3. Cette disposition des montants facilite le gerbage des barquettes sans déformation.The first is that they are not straight but angular: they indeed have a first part 9 in the vicinity of the bottom, more inclined to the vertical than the second part 10 in the vicinity of the belt. The articulation line 11 is visible in FIG. 3. This arrangement of the uprights facilitates stacking of the trays without deformation.

La seconde est que deux côtés adjacents de la barquette n'ont pas le même nombre de montants. Ainsi, sur la figure 1, le côté du fond porte deux montants 4 et 5 tandis que le côté droit n'en porte qu'un, 3, qui est bien visible sur la figure 2. Cette disposition permet le gerbage après rotation d'un quart de tour de la barquette supérieure, sans déformation de la barquette. En effet, on évite ainsi de gerber montant sur montant.The second is that two adjacent sides of the tray do not have the same number of uprights. Thus, in Figure 1, the side of the bottom carries two uprights 4 and 5 while the right side carries only one, 3, which is clearly visible in Figure 2. This arrangement allows stacking after rotation of a quarter turn of the upper tray, without deformation of the tray. Indeed, it avoids stacking amount on amount.

Avec la barquette selon l'invention, toutes les ampoules sont à la même hauteur car le fond est très plat. On peut donc gerber plusieurs barquettes pleines sans difficulté sur une plaque de support posée sur une palette. Les barquettes situées en haut des piles peuvent avantageusement être recouvertes d'une barquette retournée pour protéger les ouvertures des ampoules des chocs extérieurs. L'ensemble est alors enveloppé d'une housse rétractable, mettant ainsi l'ensemble à l'abri de toute poussière extérieure.With the tray according to the invention, all the bulbs are at the same height because the bottom is very flat. It is therefore possible to stack several full trays without difficulty on a support plate placed on a pallet. The trays located at the top of the piles can advantageously be covered with an inverted tray to protect the openings of the bulbs from external shocks. The assembly is then wrapped in a retractable cover, thus protecting the assembly from any external dust.

A l'arrivée au laboratoire de remplissage, les barquettes sont manipulées avec leurs ampoules et elles accompagnent ces ampoules au cours des opérations de remplissage sous vide, de passage à l'autoclave, de lavage, de soudage, etc... Après conditionnement des ampoules sur chevalet, les barquettes sont gerbées après rotation relative de 90°. Elles peuvent être détruites, ou réutilisées dans d'autres applications.On arrival at the filling laboratory, the trays are handled with their ampoules and they accompany these ampoules during vacuum filling operations, autoclaving, washing, welding, etc. After packaging bulbs on easel, the trays are stacked after relative rotation of 90 °. They can be destroyed, or reused in other applications.

On doit remarquer que toutes les opérations effectuées au laboratoire peuvent être entièrement automatiques, y compris la destruction des barquettes, ce qui évite tout risque de pollution lié à la réutilisation.It should be noted that all the operations carried out in the laboratory can be fully automatic, including the destruction of the trays, which avoids any risk of pollution linked to reuse.

Selon une variante de réalisation, au lieu d'un seul montant 3 sur l'un de deux côtés adjacents de la barquette, on prévoit deux montants, mais dont la disposition n'est pas identique à celle des deux montants 4 et 5 de l'autre côté adjacent, de façon à ne pas faire un gerbage montant sur montant.According to an alternative embodiment, instead of a single upright 3 on one of two adjacent sides of the tray, two uprights are provided, but the arrangement of which is not identical to that of the two uprights 4 and 5 on the other adjacent side, so as not to stack up on an upright.

En outre, on peut prévoir aux angles de la barquette, une butée telle que 12, de façon à assurer le gerbage des barquettes vides, sans déformation.In addition, one can provide at the corners of the tray, a stop such as 12, so as to ensure the stacking of empty trays, without deformation.

Il demeure bien entendu que l'invention n'est pas limitée au mode de réalisation décrit ci-dessus.Obviously, the invention is not limited to the embodiment described above.

Claims (8)

1. Barquette jetable pour le conditionnement des ampoules pharmaceutiques à remplir sous vide, du type dans lequel les ampoules sont disposées verticalement côte à côte, caractérisée en ce qu'elle est constituée d'un fond carré (1) plat, d'une ceinture (2) légèrement plus large que le fond (1) et de montants obliques (3-6) pour relier le fond à la ceinture.1. Disposable tray for packaging pharmaceutical ampoules to be filled under vacuum, of the type in which the ampoules are arranged vertically side by side, characterized in that it consists of a flat square bottom (1), of a belt (2) slightly wider than the bottom (1) and oblique uprights (3-6) to connect the bottom to the belt. 2. Barquette selon la revendication 1, caractérisée en ce que le fond (1) est bordé d'une nervure (7) pour assurer le maintien des ampoules.2. Tray according to claim 1, characterized in that the bottom (1) is bordered by a rib (7) to maintain the bulbs. 3. Barquette selon la revendication 2, caractérisée en ce qu'au voisinage des angles, ladite nervure présente des saignées (8) pour l'évacuation d'un liquide éventuel.3. Tray according to claim 2, characterized in that in the vicinity of the angles, said rib has grooves (8) for the evacuation of any liquid. 4. Barquette selon la revendication 1, caractérisée en ce que les montants comportent une première partie (9) au voisinage du fond, et une seconde partie (10) au voisinage de la ceinture (2), la première partie étant plus inclinée sur la verticale que la seconde.4. Tray according to claim 1, characterized in that the uprights comprise a first part (9) in the vicinity of the bottom, and a second part (10) in the vicinity of the belt (2), the first part being more inclined on the vertical than the second. 5. Barquette selon la revendication 1, caractérisée en ce qu'elle est constituée en matière plastique du type polypropylène chargé jusqu'à 20 9 de talc.5. Tray according to claim 1, characterized in that it is made of plastic material of the polypropylene type loaded up to 20 9 talc. 6. Barquette selon la revendication 1, caractérisée en ce que deux côtés adjacents de la barquette présentent l'un deux montants (4,5) régulièrement répartis, l'autre un seul montant (3) en son milieu.6. Tray according to claim 1, characterized in that two adjacent sides of the tray have one two uprights (4,5) regularly distributed, the other a single upright (3) in the middle. 7. Barquette selon la revendication 6 , caractérisée en ce que pour le gerbage à vide, elle est décalée de 90° par rapport à la barquette inférieure pour éviter les déformations.7. Tray according to claim 6, characterized in that for empty stacking, it is offset by 90 ° relative to the lower tray to avoid deformation. 8. Barquette selon la revendication 1, caractérisée en ce que lorsqu'elle est pleine d'ampoules à remplir, la barquette est gerbable pour expédition sur palette, la barquette du haut de chaque pile étant recouverte d'une barquette vide retournée, et l'ensemble des piles étant scellé sous housse rétractable.8. Tray according to claim 1, characterized in that when it is full of ampoules to be filled, the tray is stackable for shipping on a pallet, the tray at the top of each stack being covered with an empty inverted tray, and l 'the set of batteries being sealed under a retractable cover.
EP85401584A 1984-08-08 1985-08-02 Disposable container for the packaging of pharmaceutical ampoules filled under vacuum Expired EP0171333B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT85401584T ATE34360T1 (en) 1984-08-08 1985-08-02 DISPOSABLE CONTAINERS FOR PACKAGING PHARMACEUTICAL VACUUM SEALED AMPOULES.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8412527 1984-08-08
FR8412527A FR2568858B1 (en) 1984-08-08 1984-08-08 DISPOSABLE CONTAINER FOR THE CONDITIONING OF PHARMACEUTICAL BULBS TO BE FILLED IN VACUUM

Publications (2)

Publication Number Publication Date
EP0171333A1 true EP0171333A1 (en) 1986-02-12
EP0171333B1 EP0171333B1 (en) 1988-05-18

Family

ID=9306901

Family Applications (1)

Application Number Title Priority Date Filing Date
EP85401584A Expired EP0171333B1 (en) 1984-08-08 1985-08-02 Disposable container for the packaging of pharmaceutical ampoules filled under vacuum

Country Status (7)

Country Link
EP (1) EP0171333B1 (en)
AT (1) ATE34360T1 (en)
DE (1) DE3562748D1 (en)
EG (1) EG16865A (en)
ES (1) ES288594Y (en)
FR (1) FR2568858B1 (en)
MA (1) MA20500A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609248A (en) * 1992-10-21 1997-03-11 F. H. Faulding & Co. Limited Multi-part package

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2738914A (en) * 1950-10-31 1956-03-20 Keyes Fibre Co Fruit and vegetable container
EP0037326A1 (en) * 1980-04-02 1981-10-07 Allibert Sa. A nesting and stacking container presenting skeleton-construction sides
FR2505300A1 (en) * 1981-05-11 1982-11-12 Ampoules Mecaniques Ste Fse Polypropylene tray for holding glass ampoules - has deep sidewalls, stiffening the tray and gripping the ampoules better

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2738914A (en) * 1950-10-31 1956-03-20 Keyes Fibre Co Fruit and vegetable container
EP0037326A1 (en) * 1980-04-02 1981-10-07 Allibert Sa. A nesting and stacking container presenting skeleton-construction sides
FR2505300A1 (en) * 1981-05-11 1982-11-12 Ampoules Mecaniques Ste Fse Polypropylene tray for holding glass ampoules - has deep sidewalls, stiffening the tray and gripping the ampoules better

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609248A (en) * 1992-10-21 1997-03-11 F. H. Faulding & Co. Limited Multi-part package

Also Published As

Publication number Publication date
ES288594U (en) 1986-01-16
EP0171333B1 (en) 1988-05-18
MA20500A1 (en) 1986-04-01
EG16865A (en) 1990-12-30
ATE34360T1 (en) 1988-06-15
ES288594Y (en) 1986-09-16
FR2568858A1 (en) 1986-02-14
FR2568858B1 (en) 1987-02-06
DE3562748D1 (en) 1988-06-23

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