EP0086251A1 - Bouchons pour tubes à essais et similaires - Google Patents
Bouchons pour tubes à essais et similaires Download PDFInfo
- Publication number
- EP0086251A1 EP0086251A1 EP82107351A EP82107351A EP0086251A1 EP 0086251 A1 EP0086251 A1 EP 0086251A1 EP 82107351 A EP82107351 A EP 82107351A EP 82107351 A EP82107351 A EP 82107351A EP 0086251 A1 EP0086251 A1 EP 0086251A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- stopper
- annular
- flange portion
- diaphragm
- stopper apparatus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D39/00—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers
- B65D39/04—Cup-shaped plugs or like hollow flanged members
Definitions
- this invention relates to a new stopper for test tubes. More particularly, this invention relates to a new configuration of stopper for blood collection containers such as serum separation tubes, for example.
- the new stopper in accordance herewith, is configured to have dimensions relative to the diameter of the cooperating tube wherein the bulk of the stopper is substantially reduced. This, of course, is very important during the mass production of, for example, serum separation tubes wherein the stopper is inserted into the tube partially and a vacuum is applied to evacuate each of the tubes. Subsequent to this application, each stopper is finally seated in its respective tube.
- the cannula penetration diaphragm thereof has a thickness throughout the diameter thereof which is constant. That is, the diaphragm wall does not increase in thickness from the axis thereof radially outwardly of the stopper. The entire diaphragm is substantially constant in its thickness. Because of this, needle occlusion is avoided by the user to a substantial extent during insertion of the needle or cannula into the diaphragm. In essence, the effective area of the diaphragm is substantially increased for use, thus reducing the need for an exacting determination of the insertion point.
- the stopper of the invention provides a penetration diaphragm of substantially less thickness. This, in turn, reduces the penetration force necessary for cannula penetration of the diaphragm by at least ten percent.
- the reduction in thickness of the diaphragm together with this thickness being constant over the entire diameter of the diaphragm reduces the bulk of the stopper as discussed above and, in accordance with conventional mass production techniques, reduces the quantity of material utilized for each stopper.
- the amount of savings of materials over a period of production of, for example, one year is substantial.
- stoppers for test tubes in the past, and particularly blood collection tubes it is conventional in forming the puncture diaphragm centrally of the stopper for the insertion of a cannula to introduce a blood sample into a serum separation tube, to form a well in the top of the stopper.
- the walls of the well are curved from the top annular edge surface of the stopper to the central lower surface of the well at the axis of the stopper with the walls tapering gradually downwardly in a smooth curve to the axis of the stopper.
- the bottom surface of the prior art stopper includes an undercut area forming a well in the bottom surface of the stopper with generally the same gradually curved walls of the well from the annular bottom edge of the stopper to the axis of the stopper.
- the opposed wells at the top and the bottom of the stopper cooperate to provide a centrally positioned puncture diaphragm with the thinnest portion thereof being coaxial with the axis of the stopper and generally in the vicinity of the axis of the stopper.
- the new stopper in accordance herewith, which is configured to maximize the areas of the stopper diameter which are of a thickness to provide a desirable puncture diaphragm area for penetration by a blood collection cannula.
- a stopper for a test tube such as a blood collection tube
- which stopper has a cannula puncture diaphragm of substantially constant thickness throughout the diameter thereof, for reducing the penetration force necessary for penetration of the diaphragm and for reducing to a minimum cannula occlusion because of incorrect insertion of the cannula coaxially with the stopper.
- the stopper of the invention may be comprised of any conventional elastomer, such as a natural rubber, or a synthetic rubber such as acrylonitrile-butadiene-styrene terpolymer or various known butyl rubbers.
- Fig. 1 illustrates the stopper 10 of the invention in a side elevational view showing the body portion 14'of stopper 10 and an upper flange portion 16.
- the body portion 14 has tapered walls 12 extending from the annular bottom wall 26 of the stopper to a ledge 20.
- Ledge 20 has a locking groove 22 for cooperating with the lip of a tube into which the body portion 14 of stopper -10 is inserted.
- Upper annular flange portion 16 of stopper 10 has tapered walls 18 converging toward the axis of stopper 10 from ledge 20 to the annular top edge 24.
- stopper 10 has an annular thin puncture diaphragm 62 defined by an upper cut 64 and an opposed undercut 66.
- the puncture diaphragm 62 has a substantially constant thickness throughout the diameter thereof, with upper wall 30 and lower wall 34 thereof being substantially straight across from the tapered annular wall 32 forming the walls of the upper cut or well 64 and the annular lower wall 38 forming the lower undercut or well 66.
- annular wall 38 cooperates with annular tapered wall 12 to form an annular skirt 36 which defines the lower third of stopper 10.
- the bulk and/or thickness of this skirt 36 is substantially reduced, as will be appreciated, because of the relative vertical walls 38 which, in turn, reduce the resistance of the insertion force necessary to insert stopper 10 into a cooperating test tube.
- the lower end surface 26 of skirt 36 includes an annular tapered wall 28 which facilitates, also, insertion of stopper 10 into a tube.
- the dimensions of the stopper may vary, according to the size of the cooperating test tube for which the stopper is used.
- the diameter 42 the stopper 10 may be, for example, 17.42mm.
- the dimension 44 as shown in Fig. 4 is 16.00mm
- the dimension 46 of the upper cap portion 16 of stopper 10 is 6.35mm
- the lower body portion 14 of stopper 10 has a vertical dimension 48 of 10.20mm.
- the diameter 52 of undercut or lower well 66 in Fig. 4 is 9.32mm
- the vertical thickness 56 of puncture diaphragm 62 is 5.97mm.
- the radius 60 (Fig. 2) is 7.06mm.
- an improved stopper is provided for test tubes such as blood collection tubes, for example, which includes a puncture diaphragm which is thinner, softer and less resistant to penetration by a cannula. Because of this, it is much easier to penetrate the stopper during veni-puncture and much easier to remove and reinsert the stopper, once the tube is removed to the lab for testing of its contents. As will be appreciated, further, from the above description, the substantially constant thickness of the diameter of the diaphragm of the stopper reduces the possibility of cannula occlusion. This, of course, reduces the accuracy necessary for penetration of the puncture diaphragm of the stopper.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34933682A | 1982-02-16 | 1982-02-16 | |
US349336 | 1982-02-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0086251A1 true EP0086251A1 (fr) | 1983-08-24 |
Family
ID=23371956
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP82107351A Withdrawn EP0086251A1 (fr) | 1982-02-16 | 1982-08-13 | Bouchons pour tubes à essais et similaires |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0086251A1 (fr) |
JP (1) | JPS58142256A (fr) |
AU (1) | AU8709682A (fr) |
BR (1) | BR8204761A (fr) |
ZA (1) | ZA825774B (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985005039A1 (fr) * | 1984-05-08 | 1985-11-21 | Ballies Uwe W | Support pour eprouvettes avec dispositif d'evacuation |
EP0273114A1 (fr) * | 1986-12-29 | 1988-07-06 | Becton, Dickinson and Company | Bouchon généré par calculateur |
WO1994003373A1 (fr) * | 1992-08-07 | 1994-02-17 | The West Company, Incorporated | Bouchon a acces sans aiguille |
EP0675830A1 (fr) * | 1992-12-30 | 1995-10-11 | Abbott Laboratories | Bouchon a fine membrane pour dispositif penetrant non pointu |
EP0922648A3 (fr) * | 1997-12-09 | 1999-12-01 | Helvoet Pharma Belgium N.V. | Bouchon pour bouteilles à infusion |
EP2185435A1 (fr) * | 2007-08-01 | 2010-05-19 | Hospira, Inc. | Système de mélange de médicaments |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005011495A1 (fr) | 2003-07-18 | 2005-02-10 | Sekisui Chemical Co., Ltd. | Recipient ferme hermetiquement et recipient collecteur de substance d'essai sous vide |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3898046A (en) * | 1973-04-23 | 1975-08-05 | Jintan Terumo Co | Stopper for sealing containers |
US3958572A (en) * | 1974-12-16 | 1976-05-25 | Corning Glass Works | Blood collecting and separating assembly stopper |
GB1444210A (en) * | 1974-04-26 | 1976-07-28 | Becton Dickinson Co | Stoppers for closing containers |
GB2026995A (en) * | 1978-08-01 | 1980-02-13 | Coulter Electronics | Closure Caps |
DE3106718A1 (de) * | 1980-02-25 | 1981-12-17 | Takeda Chemical Industries, Ltd., Osaka | Aus gummi bestehender verschluss fuer ein flaeschchen oder aehnliches behaeltnis |
GB2081688A (en) * | 1980-08-06 | 1982-02-24 | Sherwood Medical Ind Inc | Anticoagulant Stopper Coating |
-
1982
- 1982-08-10 ZA ZA825774A patent/ZA825774B/xx unknown
- 1982-08-12 AU AU87096/82A patent/AU8709682A/en not_active Abandoned
- 1982-08-13 EP EP82107351A patent/EP0086251A1/fr not_active Withdrawn
- 1982-08-13 BR BR8204761A patent/BR8204761A/pt unknown
- 1982-08-16 JP JP57142016A patent/JPS58142256A/ja active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3898046A (en) * | 1973-04-23 | 1975-08-05 | Jintan Terumo Co | Stopper for sealing containers |
GB1444210A (en) * | 1974-04-26 | 1976-07-28 | Becton Dickinson Co | Stoppers for closing containers |
US3958572A (en) * | 1974-12-16 | 1976-05-25 | Corning Glass Works | Blood collecting and separating assembly stopper |
GB2026995A (en) * | 1978-08-01 | 1980-02-13 | Coulter Electronics | Closure Caps |
DE3106718A1 (de) * | 1980-02-25 | 1981-12-17 | Takeda Chemical Industries, Ltd., Osaka | Aus gummi bestehender verschluss fuer ein flaeschchen oder aehnliches behaeltnis |
GB2081688A (en) * | 1980-08-06 | 1982-02-24 | Sherwood Medical Ind Inc | Anticoagulant Stopper Coating |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985005039A1 (fr) * | 1984-05-08 | 1985-11-21 | Ballies Uwe W | Support pour eprouvettes avec dispositif d'evacuation |
EP0273114A1 (fr) * | 1986-12-29 | 1988-07-06 | Becton, Dickinson and Company | Bouchon généré par calculateur |
AU593686B2 (en) * | 1986-12-29 | 1990-02-15 | Becton Dickinson & Company | Computer generated stopper |
WO1994003373A1 (fr) * | 1992-08-07 | 1994-02-17 | The West Company, Incorporated | Bouchon a acces sans aiguille |
EP0675830A1 (fr) * | 1992-12-30 | 1995-10-11 | Abbott Laboratories | Bouchon a fine membrane pour dispositif penetrant non pointu |
EP0675830A4 (fr) * | 1992-12-30 | 1997-12-29 | Abbott Lab | Bouchon a fine membrane pour dispositif penetrant non pointu. |
EP0922648A3 (fr) * | 1997-12-09 | 1999-12-01 | Helvoet Pharma Belgium N.V. | Bouchon pour bouteilles à infusion |
EP2185435A1 (fr) * | 2007-08-01 | 2010-05-19 | Hospira, Inc. | Système de mélange de médicaments |
EP2185435A4 (fr) * | 2007-08-01 | 2014-06-11 | Hospira Inc | Système de mélange de médicaments |
Also Published As
Publication number | Publication date |
---|---|
AU8709682A (en) | 1983-08-25 |
JPS58142256A (ja) | 1983-08-24 |
ZA825774B (en) | 1983-06-29 |
BR8204761A (pt) | 1984-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Designated state(s): BE DE FR GB IT LU NL SE |
|
17P | Request for examination filed |
Effective date: 19830923 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19850228 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: PERCARPIO, EDWARD P. |